lidocaine has been researched along with Acute Disease in 243 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Acute Disease: Disease having a short and relatively severe course.
Excerpt | Relevance | Reference |
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"This randomized study suggests that topical 1% lidocaine ear drops with paracetamol or ibuprofen seems to provide effective and rapid relief for children presenting with ear pain attributed to AOM." | 9.51 | The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media. ( Alabaz, D; Albayrak, E; Bedir, T; Bozdemir, ŞE; Büyükcam, A; Çelebi, S; Çiftçi, E; İlarslan, EÇ; Kara, A; Kara, M; Kara, SS; Kara, TT; Karakaşlılar, S; Karbuz, A; Kaya, C; Öz, FN; Özdemir, H; Sali, E; Somer, A; Sönmez, G; Sütçü, M; Tezer, H, 2022) |
"An echinacea/sage preparation is as efficacious and well tolerated as a chlorhexidine/lidocaine spray in the treatment of acute sore throats." | 9.14 | Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial. ( Berger, D; Klein, P; Schapowal, A; Suter, A, 2009) |
"Topical lidocaine has been recently marketed as a new treatment for post-herpetic neuralgia." | 9.10 | Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster. ( Benowitz, NL; Campbell, BJ; Davies, PS; Jacob, P; Rowbotham, M, 2002) |
"Our study clearly demonstrates that the use of topical nifedipine, which at present is for treatment of cardiovascular disorders, is a reliable new option in the conservative treatment of thrombosed external hemorrhoids." | 9.09 | Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine. ( Antropoli, C; Antropoli, M; De Stefano, G; Molino, D; Perrotti, P, 2001) |
"Topical application of nitroglycerine represents a new, easily handled, and effective alternative in the treatment of anal fissures." | 9.08 | Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy? ( Bacher, H; Cerwenka, H; El-Shabrawi, A; Mischinger, HJ; Pfeifer, J; Schweiger, W; Werkgartner, G, 1997) |
"Fifty-five patients with shoulder pain due to rotator cuff tendinitis of less than 12 weeks' duration were randomized to receive either 40 mg methylprednisolone and lignocaine or lignocaine alone." | 9.07 | A double-blind trial comparing subacromial methylprednisolone and lignocaine in acute rotator cuff tendinitis. ( Hazleman, BL; King, RH; Vecchio, PC, 1993) |
"The treatment of dyspepsia in the emergency department often consists of antacid in combination with viscous lidocaine, even though the specific etiology of the pain is frequently unknown." | 9.06 | The emergency department treatment of dyspepsia with antacids and oral lidocaine. ( Watson, WA; Welling, LR, 1990) |
"In this double-blind parallel study, 99 patients with acute ventricular tachyarrhythmias after open-heart surgery were given either tocainide (50 patients) or lidocaine (49 patients) intravenously as 2 bolus injections 15 minutes apart, plus a fixed-rate infusion that started at the first bolus." | 9.05 | Efficacy and safety of intravenous tocainide compared with intravenous lidocaine for acute ventricular arrhythmias immediately after cardiac surgery. ( Harley, S; Johnson, J; MacVaugh, H; Morganroth, J; Panidis, IP; Smith, E, 1984) |
"Twenty-six patients with clinically significant ventricular arrhythmias were randomly assigned to treatment with either intravenous disopyramide or lidocaine; crossover to the other agent was permitted in nine cases of primary drug failure." | 9.04 | Suppression of ventricular arrhythmias with intravenous disopyramide and lidocaine: efficacy comparison in a randomized trial. ( Fozzard, HA; Rawling, DA; Sbarbaro, JA, 1979) |
"Patients with suspected or proven acute myocardial infarction complicated by ventricular arrhythmias not corrected by lidocaine therapy (bolus dose 100 mg followed by infusion 2 mg/min) were treated either with an increased dose of lidocaine (bolus dose 50 mg followed by infusion 3 mg/min) or with 600 mg N,N-bis dimethylammonium chloride (QX-572, Astra, Sweden) as an i." | 9.04 | Lidocaine and the quarternary ammonium compound QX-572 in acute myocardial infarction. A comparative study. ( Bergdahl, B; Karlsson, E; Magnusson, JO; Sonnhag, C, 1978) |
"In acute myocardial infarction, lidocaine is considered the drug of choice for the treatment of malignant ventricular arrhythmias." | 8.78 | Lidocaine in the early phase of acute myocardial infarction: the controversy over prophylactic or selective use. ( Just, H; Kasper, W; Zehender, M, 1990) |
"Intra-arterial lidocaine infusion into the celiac trunk decreases pancreatitis severity." | 7.96 | Efficacy of intra-arterial lidocaine infusion in the treatment of cerulein-induced acute pancreatitis. ( Antkowiak, R; Antkowiak, Ł; Arent, Z; Domosławski, P; Grzegorczyn, S; Kabała, N; Nalik-Iwaniak, K; Stęplewska, K; Warmusz-Reichman, E, 2020) |
"A 37-year-old man with known intravenous drug abuse presented in the surgical ambulatory care unit with acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets into the right femoral artery." | 7.77 | Successful thrombolysis and spasmolysis of acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets. ( Bellemann, N; Boeckler, D; Hyhlik-Duerr, A; Kauczor, HU; Radeleff, B; Sommer, CM; Stampfl, U; Weber, MA, 2011) |
"This case report describes an uncommon complication (blindness) occurring after an inadvertent overdosage of a frequently used local anesthetic (lidocaine) during a regional anesthetic procedure." | 7.71 | Temporary bilateral blindness after acute lidocaine toxicity. ( Sawyer, RJ; von Schroeder, H, 2002) |
"In a rat model of intracranial balloon inflation, intrathecal lidocaine prevented cardiovascular collapse and neurogenic pulmonary edema." | 7.71 | Intrathecal lidocaine prevents cardiovascular collapse and neurogenic pulmonary edema in a rat model of acute intracranial hypertension. ( Ford, S; Hall, SR; Hong, M; Milne, B; Wang, L, 2002) |
"Despite continuing controversies regarding its antiarrhythmic and antifibrillatory efficacy lidocaine is frequently used for the treatment of ventricular arrhythmias occurring in the early phase of acute myocardial infarction (MI)." | 7.69 | Facilitation of reentry by lidocaine in canine myocardial infarction. ( Fazekas, T; Lazzara, R; Mabo, P; Patterson, E; Scherlag, BJ, 1994) |
"We evaluate the analgesic efficacy and safety of 9% (wt/vol) lidocaine (base) in petrolatum/paraffin ointment in patients with acute herpes zoster." | 7.69 | Treatment of the cutaneous pain of acute herpes zoster with 9% lidocaine (base) in petrolatum/paraffin ointment. ( Cork, RC; Dunston, A; Eyrich, J; Heitler, D; Johnson, W; Lopez-Anaya, A; Naraghi, M; Ragan, A; Riopelle, AJ; Riopelle, J, 1994) |
"The effects of acute changes in plasma magnesium concentration on the threshold for lidocaine-induced seizures were evaluated in mechanically ventilated rats receiving 70% nitrous oxide and 30% oxygen." | 7.68 | Effects of acute hypermagnesemia on the threshold for lidocaine-induced seizures in the rat. ( Choi, WW; Monahan, DJ; Todd, MM; Warner, DS, 1991) |
"To evaluate the pharmacodynamics of intravenous lidocaine in patients with acute-onset and chronic ventricular arrhythmias." | 7.68 | Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias. ( Destache, CJ; Hilleman, DE; Hunter, CB; Mohiuddin, SM; Mooss, AN; Sketch, MH, 1992) |
" The new strategy has been illustrated in a case-control investigation of whether lidocaine prophylaxis prevents death in patients with acute myocardial infarction." | 7.66 | Improved observational method for studying therapeutic efficacy. Suggestive evidence that lidocaine prophylaxis prevents death in acute myocardial infarction. ( Feinstein, AR; Horwitz, RI, 1981) |
"An acute pharyngitis is characterised by mild to severe sore throat mostly accompanied by inflammation, throat pain, pain on swallowing, and burning." | 6.73 | Lidocaine 8 mg sore throat lozenges in the treatment of acute pharyngitis. A new therapeutic option investigated in comparison to placebo treatment. ( Blume, HH; Canenbley, R; Donath, F; Helm, I; Nowak, H; Röttger-Luer, P; Schug, BS; Stauss-Grabo, M; Tran, CT; Wonnemann, M, 2007) |
"This randomized study suggests that topical 1% lidocaine ear drops with paracetamol or ibuprofen seems to provide effective and rapid relief for children presenting with ear pain attributed to AOM." | 5.51 | The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media. ( Alabaz, D; Albayrak, E; Bedir, T; Bozdemir, ŞE; Büyükcam, A; Çelebi, S; Çiftçi, E; İlarslan, EÇ; Kara, A; Kara, M; Kara, SS; Kara, TT; Karakaşlılar, S; Karbuz, A; Kaya, C; Öz, FN; Özdemir, H; Sali, E; Somer, A; Sönmez, G; Sütçü, M; Tezer, H, 2022) |
" High-dose topiramate combined with high-dose lidocaine infusion or high-dose phenobarbital in the acute stage might be an effective treatment option for children with AERRPS." | 5.35 | Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures. ( Hsia, SH; Lin, JJ; Lin, KL; Wang, HS; Wu, CT, 2009) |
"Pretreatment with lidocaine also greatly attenuated the acute hypertension and the increase in intracranial pressure following air embolism." | 5.27 | Protective effect of lidocaine in acute cerebral ischemia induced by air embolism. ( Bradley, ME; Evans, DE; Kobrine, AI; LeGrys, DC, 1984) |
"An echinacea/sage preparation is as efficacious and well tolerated as a chlorhexidine/lidocaine spray in the treatment of acute sore throats." | 5.14 | Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial. ( Berger, D; Klein, P; Schapowal, A; Suter, A, 2009) |
"From this preliminary study, intravenous injection of lidocaine seems to be safe and effective in controlling intraocular pressure and eliminating symptoms in acute PACG." | 5.12 | Efficacy and safety of intravenous injection of lidocaine in the treatment of acute primary angle-closure glaucoma: a pilot study. ( Dong, XD; Jin, X; Qin, Q; Qu, J; Xue, A; Zhao, Y, 2007) |
"Topical lidocaine has been recently marketed as a new treatment for post-herpetic neuralgia." | 5.10 | Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster. ( Benowitz, NL; Campbell, BJ; Davies, PS; Jacob, P; Rowbotham, M, 2002) |
"Our study clearly demonstrates that the use of topical nifedipine, which at present is for treatment of cardiovascular disorders, is a reliable new option in the conservative treatment of thrombosed external hemorrhoids." | 5.09 | Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine. ( Antropoli, C; Antropoli, M; De Stefano, G; Molino, D; Perrotti, P, 2001) |
"Topical application of nitroglycerine represents a new, easily handled, and effective alternative in the treatment of anal fissures." | 5.08 | Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy? ( Bacher, H; Cerwenka, H; El-Shabrawi, A; Mischinger, HJ; Pfeifer, J; Schweiger, W; Werkgartner, G, 1997) |
"Fifty-five patients with shoulder pain due to rotator cuff tendinitis of less than 12 weeks' duration were randomized to receive either 40 mg methylprednisolone and lignocaine or lignocaine alone." | 5.07 | A double-blind trial comparing subacromial methylprednisolone and lignocaine in acute rotator cuff tendinitis. ( Hazleman, BL; King, RH; Vecchio, PC, 1993) |
"The treatment of dyspepsia in the emergency department often consists of antacid in combination with viscous lidocaine, even though the specific etiology of the pain is frequently unknown." | 5.06 | The emergency department treatment of dyspepsia with antacids and oral lidocaine. ( Watson, WA; Welling, LR, 1990) |
"In this double-blind parallel study, 99 patients with acute ventricular tachyarrhythmias after open-heart surgery were given either tocainide (50 patients) or lidocaine (49 patients) intravenously as 2 bolus injections 15 minutes apart, plus a fixed-rate infusion that started at the first bolus." | 5.05 | Efficacy and safety of intravenous tocainide compared with intravenous lidocaine for acute ventricular arrhythmias immediately after cardiac surgery. ( Harley, S; Johnson, J; MacVaugh, H; Morganroth, J; Panidis, IP; Smith, E, 1984) |
"Twenty-six patients with clinically significant ventricular arrhythmias were randomly assigned to treatment with either intravenous disopyramide or lidocaine; crossover to the other agent was permitted in nine cases of primary drug failure." | 5.04 | Suppression of ventricular arrhythmias with intravenous disopyramide and lidocaine: efficacy comparison in a randomized trial. ( Fozzard, HA; Rawling, DA; Sbarbaro, JA, 1979) |
"Patients with suspected or proven acute myocardial infarction complicated by ventricular arrhythmias not corrected by lidocaine therapy (bolus dose 100 mg followed by infusion 2 mg/min) were treated either with an increased dose of lidocaine (bolus dose 50 mg followed by infusion 3 mg/min) or with 600 mg N,N-bis dimethylammonium chloride (QX-572, Astra, Sweden) as an i." | 5.04 | Lidocaine and the quarternary ammonium compound QX-572 in acute myocardial infarction. A comparative study. ( Bergdahl, B; Karlsson, E; Magnusson, JO; Sonnhag, C, 1978) |
"In acute myocardial infarction, lidocaine is considered the drug of choice for the treatment of malignant ventricular arrhythmias." | 4.78 | Lidocaine in the early phase of acute myocardial infarction: the controversy over prophylactic or selective use. ( Just, H; Kasper, W; Zehender, M, 1990) |
" Early and adequate intravenous antiarrhythmic prophylaxis with lidocaine to raise the fibrillation threshold in the setting of coronary insufficiency can prevent primary ventricular fibrillation." | 4.75 | The management of acute coronary insufficiency. ( Baker, J; Greenfield, JC; Wagner, GS, 1977) |
"Intra-arterial lidocaine infusion into the celiac trunk decreases pancreatitis severity." | 3.96 | Efficacy of intra-arterial lidocaine infusion in the treatment of cerulein-induced acute pancreatitis. ( Antkowiak, R; Antkowiak, Ł; Arent, Z; Domosławski, P; Grzegorczyn, S; Kabała, N; Nalik-Iwaniak, K; Stęplewska, K; Warmusz-Reichman, E, 2020) |
"A 37-year-old man with known intravenous drug abuse presented in the surgical ambulatory care unit with acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets into the right femoral artery." | 3.77 | Successful thrombolysis and spasmolysis of acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets. ( Bellemann, N; Boeckler, D; Hyhlik-Duerr, A; Kauczor, HU; Radeleff, B; Sommer, CM; Stampfl, U; Weber, MA, 2011) |
" Subdiaphragmatic vagotomy and abdominal perivagal lidocaine administration, or lidocaine injection into the nucleus tractus solitarius (NTS) prevented LPS hypotension." | 3.74 | Lipopolysaccharide-induced hypotension is mediated by a neural pathway involving the vagus nerve, the nucleus tractus solitarius and alpha-adrenergic receptors in the preoptic anterior hypothalamic area. ( Cutrera, RA; Feleder, C; Goktalay, G; Millington, WR; Myer, BS; Yilmaz, MS, 2008) |
"In a rat model of intracranial balloon inflation, intrathecal lidocaine prevented cardiovascular collapse and neurogenic pulmonary edema." | 3.71 | Intrathecal lidocaine prevents cardiovascular collapse and neurogenic pulmonary edema in a rat model of acute intracranial hypertension. ( Ford, S; Hall, SR; Hong, M; Milne, B; Wang, L, 2002) |
"This case report describes an uncommon complication (blindness) occurring after an inadvertent overdosage of a frequently used local anesthetic (lidocaine) during a regional anesthetic procedure." | 3.71 | Temporary bilateral blindness after acute lidocaine toxicity. ( Sawyer, RJ; von Schroeder, H, 2002) |
"Metaanalysis of data from 20 years of randomized trials of lidocaine prophylaxis in preventing primary ventricular fibrillation (VF) in myocardial infarction used separate data for control and active-treatment groups to model the risk of VF as a function of year of publication and other study characteristics." | 3.69 | Advantages and limitations of metaanalytic regressions of clinical trials data. ( Antman, EM; Berlin, JA, 1994) |
"The aim of this study was to elucidate whether the electrophysiologic properties of pilsicainide, a novel class IC drug with slow kinetic properties, could be altered in the presence of acute myocardial ischemia." | 3.69 | Ischemia enhances use-dependent sodium channel blockade by pilsicainide, a class IC antiarrhythmic agent. ( Ogawa, S; Sadanaga, T, 1994) |
"We evaluate the analgesic efficacy and safety of 9% (wt/vol) lidocaine (base) in petrolatum/paraffin ointment in patients with acute herpes zoster." | 3.69 | Treatment of the cutaneous pain of acute herpes zoster with 9% lidocaine (base) in petrolatum/paraffin ointment. ( Cork, RC; Dunston, A; Eyrich, J; Heitler, D; Johnson, W; Lopez-Anaya, A; Naraghi, M; Ragan, A; Riopelle, AJ; Riopelle, J, 1994) |
"Despite continuing controversies regarding its antiarrhythmic and antifibrillatory efficacy lidocaine is frequently used for the treatment of ventricular arrhythmias occurring in the early phase of acute myocardial infarction (MI)." | 3.69 | Facilitation of reentry by lidocaine in canine myocardial infarction. ( Fazekas, T; Lazzara, R; Mabo, P; Patterson, E; Scherlag, BJ, 1994) |
"An equal degree of acute hypertension induced by these three different vasopressors may play a role in reducing the threshold (plasma and brain lidocaine concentrations) as well as the cumulative convulsant doses associated with lidocaine-induced convulsions." | 3.69 | Effect of vasoconstrictive agents added to lidocaine on intravenous lidocaine-induced convulsions in rats. ( Goto, H; Hirakawa, M; Yokoyama, M, 1995) |
"To evaluate the pharmacodynamics of intravenous lidocaine in patients with acute-onset and chronic ventricular arrhythmias." | 3.68 | Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias. ( Destache, CJ; Hilleman, DE; Hunter, CB; Mohiuddin, SM; Mooss, AN; Sketch, MH, 1992) |
"The effects of acute changes in plasma magnesium concentration on the threshold for lidocaine-induced seizures were evaluated in mechanically ventilated rats receiving 70% nitrous oxide and 30% oxygen." | 3.68 | Effects of acute hypermagnesemia on the threshold for lidocaine-induced seizures in the rat. ( Choi, WW; Monahan, DJ; Todd, MM; Warner, DS, 1991) |
"Patients with acute hepatitis and patients with compensated or decompensated cirrhosis of the liver have a decreased plasma clearance of hexobarbital." | 3.66 | [Drug metabolism in patients with liver disease (author's transl)]. ( Epping, J; Fuchshofen-Röckel, M; Heusler, H; Richter, E; Zilly, W, 1980) |
"Technetium-99m dimethyl acetanilide iminodiacetic acid (HIDA) cholescintigraphy was performed on 90 patients with suspected acute cholecystitis." | 3.66 | Rapid and accurate diagnosis of acute cholecystitis with 99mTc-HIDA cholescintigraphy. ( Bernstein, LH; Frank, MS; Freeman, LM; Weissmann, HS, 1979) |
" The new strategy has been illustrated in a case-control investigation of whether lidocaine prophylaxis prevents death in patients with acute myocardial infarction." | 3.66 | Improved observational method for studying therapeutic efficacy. Suggestive evidence that lidocaine prophylaxis prevents death in acute myocardial infarction. ( Feinstein, AR; Horwitz, RI, 1981) |
"The effect of administration of lidocaine on left ventricular performance was studied using systolic time intervals in nine normal subjects, eight patients with stable angina, and 15 patients with acute myocardial infarction." | 3.65 | Negative inotropic effect of lidocaine in patients with coronary arterial disease and normal subjects. ( Boudoulas, H; DeGreen, P; Kates, RE; Lewis, RP; Schaal, SF; Welch, TG, 1977) |
"Included patients met the migraine criteria of the International Headache Society." | 2.84 | Intranasal Lidocaine in Acute Treatment of Migraine: A Randomized Controlled Trial. ( Akalın, LE; Alyeşil, C; Avcu, N; Doğan, NÖ; Pekdemir, M; Yaka, E; Yılmaz, S, 2017) |
"Local methylcobalamin combined with lidocaine, optimally administered within 4-7 days of onset, may be an effective therapeutic option for acute herpetic neuralgia." | 2.82 | Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia. ( Cheng, C; Tang, WZ; Xǔ, G; Xu, J; Xu, S, 2016) |
"Early repair of rotator cuff tears leads to superior results." | 2.75 | The value of clinical tests in acute full-thickness tears of the supraspinatus tendon: does a subacromial lidocaine injection help in the clinical diagnosis? A prospective study. ( Bak, K; Jørgensen, U; Krarup, AL; Nygaard, M; Pedersen, ST; Sloth, C; Sørensen, AK; Thune, C, 2010) |
"An acute pharyngitis is characterised by mild to severe sore throat mostly accompanied by inflammation, throat pain, pain on swallowing, and burning." | 2.73 | Lidocaine 8 mg sore throat lozenges in the treatment of acute pharyngitis. A new therapeutic option investigated in comparison to placebo treatment. ( Blume, HH; Canenbley, R; Donath, F; Helm, I; Nowak, H; Röttger-Luer, P; Schug, BS; Stauss-Grabo, M; Tran, CT; Wonnemann, M, 2007) |
"No differences were noted in postoperative pain, the total number of analgesic doses per day, the quantity of narcotic medication administered, and the length of hospital stay." | 2.68 | Preemptive analgesia in patients undergoing appendectomy. ( Alcantara, A; Hiyama, D; Ko, CY; Thompson, JE, 1997) |
"Subjects scored the intensity of headache and nausea on separate visual analogue scales before the injection and at 10 and 20 min after injection." | 2.67 | Is intravenous lidocaine clinically effective in acute migraine? ( Fatovich, DM; Prentice, DA; Reutens, DC; Stewart-Wynne, EG, 1991) |
"It is effective against ventricular arrhythmias, both parenterally and orally, and has been used in acute myocardial infarction, in the convalescence following myocardial infarction and in ventricular arrhythmias of different aetiology." | 2.65 | Mexiletine in clinical practice. ( Boyle, DM, 1980) |
"Lidocaine should not be used to treat painful mouth lesions in children until further safety data are available." | 2.39 | Lidocaine overdose: another preventable case? ( Druckenbrod, RW; Gonzalez del Rey, J; Wason, S, 1994) |
"Ventricular arrhythmias represent a common precursor of ventricular fibrillation in acute myocardial infarction in man." | 2.36 | [Prognostic significance of arrhythmias in acute myocardial infarction (author's transl)]. ( Breithardt, G; Loogen, F; Seipel, L, 1977) |
" High-dose topiramate combined with high-dose lidocaine infusion or high-dose phenobarbital in the acute stage might be an effective treatment option for children with AERRPS." | 1.35 | Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures. ( Hsia, SH; Lin, JJ; Lin, KL; Wang, HS; Wu, CT, 2009) |
"Biliary acute pancreatitis or postendoscopic iatrogenia acute pancreatitis (AP) are likely triggered by autonomous arc reflexes (AAR) initiated in the peri-Vaterian duodenum (PV-D)." | 1.32 | Acute pancreatitis possible initial triggering mechanism and prophylaxis. ( Binker, MG; Cosen-Binker, LI; Negri, G; Tiscornia, O, 2003) |
"Because the patient developed acute renal failure and furosemide did not show diuretic effect, hemodialysis was used." | 1.30 | [Perioperative management for acute abdominal aortic obstruction in a patient with acute myocardial reinfarction associated with acute renal failure]. ( Ishiyama, T; Tsujitou, T, 1997) |
" From these findings, the present Bayesian method implemented with the estimates of pharmacokinetic parameters in a Swiss patient population is useful for sufficiently accurate and precise assessment of individual dosage requirement within a few hours after starting lidocaine therapy." | 1.29 | A prospective study for validation of Bayesian prediction approach to adjust individual lidocaine dosage. ( Hirayama, H; Kosuge, K; Nakashima, M; Uematsu, T; Umemura, K, 1994) |
"The predictive performance of two computer programs for lidocaine dosing were evaluated." | 1.28 | Predictive performance of Bayesian and nonlinear least-squares regression programs for lidocaine. ( Destache, CJ; Hilleman, DE; Lang, PT; Mohiuddin, SJ, 1992) |
"A case is reported of acute respiratory failure occurring during upper abdominal surgery in a patient not previously known to have chronic respiratory failure." | 1.28 | [Transient acute respiratory failure and thoracic epidural anesthesia]. ( Joyau, FH; Maries, H, 1989) |
"Pretreatment with lidocaine also greatly attenuated the acute hypertension and the increase in intracranial pressure following air embolism." | 1.27 | Protective effect of lidocaine in acute cerebral ischemia induced by air embolism. ( Bradley, ME; Evans, DE; Kobrine, AI; LeGrys, DC, 1984) |
"A case is reported in which acute airway obstruction followed the injection of Teflon paste into a paralysed vocal cord." | 1.27 | Respiratory obstruction following vocal cord injection of Teflon paste. ( Bates, GJ; Curley, JW; Ward, ME, 1984) |
" The absence of correlation between pharmacokinetic parameters of the disposition of lidocaine and indocyanine green indicates that the influence of hepatic disease on the hepatic processes that lead to the elimination of each compound is not predictable." | 1.26 | Influence of viral hepatitis on the disposition of two compounds with high hepatic clearance: lidocaine and indocyanine green. ( Blaschke, TF; Meffin, PJ; Melmon, KL; Rowland, M; Williams, RL, 1976) |
"The occipital pain and headache of cervical arthritis also often respond to injection of 2 to 3 ml of long-acting anesthetic into the greater and lesser occipital nerves at the sites where they pierce the trapezius." | 1.26 | Relieving pain with nerve blocks. ( Carron, H, 1978) |
" In ten of them the main pharmacokinetic parameters were determined; the average value of lidocain clearance was 0." | 1.26 | [Lidocaine pharmacokinetics and substantiation of the new method of its administration in myocardial infarct]. ( Mazur, NA; Metelitsa, VI; Piotrovskiĭ, VK; Riabokon', OS; Smirnova, EB, 1979) |
"Furthermore dangerous arrhythmias are reported in 1600 cases treated with floating catheters." | 1.26 | [Arrhythmias during catheterization of patients with acute myocardial infarction (author's transl)]. ( Enenkel, W; Jobst, C; Kiss, E; Mayer, B; Nobis, H; Pollak, H; Prachar, H; Spiel, R, 1977) |
" In a guarded ward for coronary diseases since 1972 all patients with a fresh myocardial infarction or suspicion of infarction were treated with a continuous intravenous lidocain drip in a dosage of 100 mg/per hour for 48 hours." | 1.25 | [Possibilities of a routine prevention of arrhythmia in the early phase of acute myocardial infarct]. ( Fiehring, H; Kulick, B; Schaedel, H; Steffen, V, 1975) |
"Of particular importance are the arrhythmias observed immediately after experimentally induced acute myocardial infarction (AMI)." | 1.25 | Pharmacological modification of arrhythmias after experimentally induced acute myocardial infarction. Drugs acting on the nervous system. ( Kniffen, FJ; Lucchesi, BR, 1975) |
"This arrhythmia always appeared within the first 24 hours after the beginning of the pain, and lasted usually a few hours." | 1.25 | Ventricular parasystole in acute myocardial infarction. ( McKendrick, CS; Salazar, J, 1970) |
"Nine of these had ventricular arrhythmia refractory to drugs." | 1.25 | Atrial pacing to control heart rate and rhythm in acute cardiac conditions. ( Friesen, WG, 1971) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 145 (59.67) | 18.7374 |
1990's | 40 (16.46) | 18.2507 |
2000's | 35 (14.40) | 29.6817 |
2010's | 21 (8.64) | 24.3611 |
2020's | 2 (0.82) | 2.80 |
Authors | Studies |
---|---|
Kara, A | 1 |
Büyükcam, A | 1 |
Sütçü, M | 1 |
Sali, E | 1 |
Bozdemir, ŞE | 1 |
Kara, M | 1 |
İlarslan, EÇ | 1 |
Kaya, C | 1 |
Karakaşlılar, S | 1 |
Sönmez, G | 1 |
Kara, SS | 1 |
Bedir, T | 1 |
Albayrak, E | 1 |
Kara, TT | 1 |
Çelebi, S | 1 |
Öz, FN | 1 |
Karbuz, A | 1 |
Somer, A | 1 |
Alabaz, D | 1 |
Tezer, H | 1 |
Özdemir, H | 1 |
Çiftçi, E | 1 |
Chi, PW | 2 |
Hsieh, KY | 2 |
Chen, KY | 1 |
Hsu, CW | 2 |
Bai, CH | 2 |
Chen, C | 2 |
Hsu, YP | 2 |
Antkowiak, R | 1 |
Antkowiak, Ł | 1 |
Grzegorczyn, S | 1 |
Nalik-Iwaniak, K | 1 |
Kabała, N | 1 |
Arent, Z | 1 |
Warmusz-Reichman, E | 1 |
Stęplewska, K | 1 |
Domosławski, P | 1 |
Fujii, K | 1 |
Tsai, CW | 1 |
Morgan, A | 1 |
Jessop, V | 1 |
Sun, JJ | 1 |
Chu, ZJ | 1 |
Liu, WF | 1 |
Qi, SF | 1 |
Yang, YH | 1 |
Ge, PL | 1 |
Zhang, XH | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Sphenopalatine Ganglion Blocks for Headaches in the Emergency Department[NCT04255420] | Phase 4 | 84 participants (Anticipated) | Interventional | 2020-02-21 | Recruiting | ||
Multicentric Randomized Double Blind Double Dummy Placebo Controlled Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray in Comparison to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats[NCT00707902] | Phase 3 | 154 participants (Actual) | Interventional | 2006-02-28 | Completed | ||
Double-blind Randomized Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo, in the Outpatients Area.[NCT03676556] | Phase 3 | 46 participants (Anticipated) | Interventional | 2021-06-16 | Recruiting | ||
Randomised, Double-blind Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo[NCT02584335] | Phase 4 | 7 participants (Actual) | Interventional | 2015-07-31 | Terminated (stopped due to Difficulties with the recruitment) | ||
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Lidocaine For Neuroprotection During Cardiac Surgery[NCT00938964] | 550 participants (Actual) | Interventional | 2009-07-31 | Completed | |||
Clinical Outcome in Subacute Stroke Patients With Hemiplegic Shoulder Pain and Rotator Cuff Injuries After Hyaluronic Acid Injection[NCT02465853] | 42 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
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Transdermal Microneedle Patch To Enhance Topical Anaesthesia Before Intravenous Line Insertion for Blood Transfusion In Paediatric Thalassemia Patients[NCT05078463] | Phase 2 | 20 participants (Actual) | Interventional | 2021-09-15 | Completed | ||
Intravenous Pantoprazole vs Ranitidine in Dyspepsia in Emergency Department: A Randomized Controlled Trial.[NCT01737840] | Phase 4 | 66 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
Randomized Controlled Trial Comparing the Efficacy of Polyethylene Glycol Alone and Polyethylene Glycol Combined With Topical Diltiazem in Treating Anal fissure in Children[NCT02419534] | Phase 4 | 46 participants (Anticipated) | Interventional | 2014-11-30 | Recruiting | ||
Transcranial Direct Current Stimulation for the Treatment of Parkinson's Disease[NCT00082342] | Phase 2 | 25 participants (Actual) | Interventional | 2003-03-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The primary outcome of interest will be development of acute pancreatitis defined as new or worsening abdominal pain post-ERCP associated with an increase in serum amylase at least 3 times the upper limit of normal. (NCT00953199)
Timeframe: 24-48 hours post-procedure
Intervention | participants (Number) |
---|---|
Lidocaine | 26 |
Normal Saline | 20 |
serum amylase levels are measure by a blood draw (NCT00953199)
Timeframe: measurement is taken 2 hrs after ERCP
Intervention | units/liter (Mean) |
---|---|
Lidocaine | 130 |
Normal Saline | 128 |
(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)
Intervention | minutes (Mean) |
---|---|
1:1000 Epinephrine Plus Saline | 72.05 |
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 54.23 |
(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)
Intervention | mL (Mean) |
---|---|
1:1000 Epinephrine Plus Saline | 95.25 |
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 91.63 |
Participants indicated number of days with bloody nasal discharge postoperatively using the 1-week postoperative bleeding questionnaire. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)
Intervention | days (Mean) |
---|---|
1:1000 Epinephrine Plus Saline | 2.85 |
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 2.73 |
A pledget is a small wad of absorbent material used to stop bleeding. (NCT05867342)
Timeframe: intraoperatively (up to 3 hours)
Intervention | pledgets (Mean) |
---|---|
1:1000 Epinephrine Plus Saline | 3.25 |
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 2.63 |
Number of nostrils with excessive fresh bleeding postoperatively using the 1-week postoperative bleeding questionnaire. Continuous fresh bleeding was defined as bleeding for over 15 minutes. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)
Intervention | nostrils (Count of Units) |
---|---|
1:1000 Epinephrine Plus Saline | 7 |
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 5 |
Grading of postoperative bloody discharge postoperatively assessed by patient using the 1-week postoperative bleeding questionnaire. Scores range from 0 (no bleeding) to 5 (continuous heavy bleeding necessitating medical care). (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)
Intervention | score on a scale (Mean) |
---|---|
1:1000 Epinephrine Plus Saline | 2.38 |
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 2.2 |
The video recording of the endoscopic sinus surgery of the participant was graded by another otolaryngology specialist postoperatively and graded according to Wormald Surgical Field Grading Scale. Scores range from 0 (no bleeding) to 10 (severe bleeding with nasal cavity filling rapidly). (NCT05867342)
Timeframe: postoperatively (approximately 20 minutes to assess)
Intervention | score on a scale (Mean) |
---|---|
1:1000 Epinephrine Plus Saline | 3.54 |
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 3.23 |
"Center for Epidemiological Studies Depression Scale (CES-D). The CES-D is a 20-item self-report examination designed to measure symptoms of depression. Subjects rate the degree to which they have experienced a range of symptoms of depression, such as I had crying spells and I felt lonely. Scores range from 0 to 60, with higher scores indicating greater depressive symptoms. Scores greater than 16 are typically considered indicative of clinically significant depression." (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | -1.27 |
Placebo | -0.89 |
"Center for Epidemiological Studies Depression Scale (CES-D). The CES-D is a 20-item self-report examination designed to measure symptoms of depression. Subjects rate the degree to which they have experienced a range of symptoms of depression, such as I had crying spells and I felt lonely. Scores range from 0 to 60, with higher scores indicating greater depressive symptoms. Scores greater than 16 are typically considered indicative of clinically significant depression." (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 0.57 |
Placebo | 0.16 |
To characterize cognitive function over time, while minimizing potential redundancy in the cognitive measures, a factor analysis was performed on the 14 cognitive test scores from baseline. We chose a five-factor solution, which represents 5 cognitive domains: structured verbal memory, unstructured verbal memory, executive function, visual memory and attention/concentration. To quantify overall cognitive function, a baseline cognitive index was first calculated as the mean of the 5 preoperative domain scores. The cognitive index score has a mean of zero, thus any positive score is above the mean, any negative score is below the mean. A continuous change score was then calculated by subtracting the baseline from the 1 year cognitive index. The resulting outcome measure is unbounded with standard deviation of 0.35. A negative change score indicating decline and a positive score indicating improvement (NCT00938964)
Timeframe: 1 year after surgery
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 0.09 |
Placebo | 0.07 |
To characterize cognitive function over time, while minimizing potential redundancy in the cognitive measures, a factor analysis was performed on the 14 cognitive test scores from baseline. We chose a five-factor solution, which represents 5 cognitive domains: structured verbal memory, unstructured verbal memory, executive function, visual memory and attention/concentration. To quantify overall cognitive function, a baseline cognitive index was first calculated as the mean of the 5 preoperative domain scores. The cognitive index score has a mean of zero, thus any positive score is above the mean, any negative score is below the mean. A continuous change score was then calculated by subtracting the baseline from the 6-week cognitive index. The resulting outcome measure is unbounded with standard deviation of 0.35. A negative change score indicating decline and a positive score indicating improvement. (NCT00938964)
Timeframe: Preoperative to 6 weeks after surgery
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 0.07 |
Placebo | 0.07 |
"The DASI is a 12-item scale of functional capacity that has been found to correlate well with objective measures of maximal exercise capacity. Items reflect activities of personal care, ambulation, household tasks, sexual function, and recreational activities. Activities done with no difficulty receive scores, which are weighted and summed, for a quantitative measure of functional status. Scores range from 0 to 60; a higher-weighted score indicates better function." (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 6.3 |
Placebo | 6.96 |
"The DASI is a 12-item scale of functional capacity that has been found to correlate well with objective measures of maximal exercise capacity. Items reflect activities of personal care, ambulation, household tasks, sexual function, and recreational activities. Activities done with no difficulty receive scores, which are weighted and summed, for a quantitative measure of functional status. Scores range from 0 to 60; a higher-weighted score indicates better function." (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | -10.98 |
Placebo | -11.67 |
The National Institutes of Health Stroke Scale (NIHSS) is a 15-item neurologic examination stroke scale used to evaluate the effect of acute cerebral infarction on the levels of consciousness, language, neglect, visual-field loss, extraocular movement, motor strength, ataxia, dysarthria, and sensory loss. A trained observer rates the patent's ability to answer questions and perform activities. Ratings for each item are scored with 3 to 5 grades with 0 as normal, and there is an allowance for untestable items. The range of scores is from 0 (normal) to 42 (profound effect of stroke on patient). (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 0.05 |
Placebo | 0.07 |
The National Institutes of Health Stroke Scale (NIHSS) is a 15-item neurologic examination stroke scale used to evaluate the effect of acute cerebral infarction on the levels of consciousness, language, neglect, visual-field loss, extraocular movement, motor strength, ataxia, dysarthria, and sensory loss. A trained observer rates the patent's ability to answer questions and perform activities. Ratings for each item are scored with 3 to 5 grades with 0 as normal, and there is an allowance for untestable items. The range of scores is from 0 (normal) to 42 (profound effect of stroke on patient). (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 0.05 |
Placebo | 0.04 |
The Western perioperative neurologic scale was designed to detect neurologic deficits after cardiac surgery. It includes 14 items classified into eight domains (mentation, speech, cranial nerve function, motor weakness, sensation and cerebellum, reflexes, and gait). Each item is scored from 0 (severe deficit) to3 (normal), and a maximum score of 42 indicates normal neurological function. (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 0.02 |
Placebo | -0.02 |
The Western perioperative neurologic scale was designed to detect neurologic deficits after cardiac surgery. It includes 14 items classified into eight domains (mentation, speech, cranial nerve function, motor weakness, sensation and cerebellum, reflexes, and gait). Each item is scored from 0 (severe deficit) to3 (normal), and a maximum score of 42 indicates normal neurological function. (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 0.04 |
Placebo | -0.01 |
"Perceived Social Support Scale: Twelve items indicate how strongly subjects agree that there is a special person who is around when I am in need and my family really tries to help me. Choices range from very strongly disagree to very strongly agree. Items are summed for a range of 12 to 84, with a high score meaning more social support." (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 0.71 |
Placebo | -1.16 |
"Perceived Social Support Scale: Twelve items indicate how strongly subjects agree that there is a special person who is around when I am in need and my family really tries to help me. Choices range from very strongly disagree to very strongly agree. Items are summed for a range of 12 to 84, with a high score meaning more social support." (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 1.23 |
Placebo | -0.49 |
"Social Activity: This measure consisted of eight items that indicate the degree of social interaction. Sample items are How often do you talk on the telephone with friends and relatives? and How often do you attend meetings of social groups, clubs, or civic organizations? Scores range from 8 to 32. A lower score indicates more social activity." (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | -0.20 |
Placebo | 0.03 |
"Social Activity: This measure consisted of eight items that indicate the degree of social interaction. Sample items are How often do you talk on the telephone with friends and relatives? and How often do you attend meetings of social groups, clubs, or civic organizations? Scores range from 8 to 32. A lower score indicates more social activity." (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 0.95 |
Placebo | 1.59 |
"Spielberger State Anxiety Inventory (STAI): The STAI consists of two 20-item scales that measure anxiety. Representative items include statements such as I feel nervous and I feel worried. These items are rated on a 4-point scale, based on how well they describe the patient's current or typical mood, from not at all to very much so. Scores range from 20 to 80, with higher scores indicating greater anxiety." (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | -6.70 |
Placebo | -6.39 |
"Spielberger State Anxiety Inventory (STAI): The STAI consists of two 20-item scales that measure anxiety. Representative items include statements such as I feel nervous and I feel worried. These items are rated on a 4-point scale, based on how well they describe the patient's current or typical mood, from not at all to very much so. Scores range from 20 to 80, with higher scores indicating greater anxiety." (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | -7.12 |
Placebo | -6.31 |
Symptom limitations: Patients were given a list of eight symptoms and asked to rate the degree to which the symptom limited daily activities. The symptoms were angina, shortness of breath, arthritis, back trouble, leg pains, headaches, fatigue, and other. Scores range from 8 to 32, with higher scores indicating greater limitations. (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | -1.39 |
Placebo | -1.48 |
Symptom limitations: Patients were given a list of eight symptoms and asked to rate the degree to which the symptom limited daily activities. The symptoms were angina, shortness of breath, arthritis, back trouble, leg pains, headaches, fatigue, and other. Scores range from 8 to 32, with higher scores indicating greater limitations. (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | -0.67 |
Placebo | -0.8 |
"Cognitive Difficulties Scale: a 39-item scale, is a self-report assessment of perceived problems in long- and short-term memory, concentration, attention, and psycho-motor coordination. Sample items are I forget errands I planned to do and I fail to recognize people I know. Scores range from 39 to 164, with higher scores indicating greater cognitive difficulty." (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | -0.46 |
Placebo | -1.02 |
"Cognitive Difficulties Scale: a 39-item scale, is a self-report assessment of perceived problems in long- and short-term memory, concentration, attention, and psycho-motor coordination. Sample items are I forget errands I planned to do and I fail to recognize people I know. Scores range from 39 to 164, with higher scores indicating greater cognitive difficulty." (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | -3 |
Placebo | -3.21 |
"Duke Older Americans Resources and Services Procedures- Instrumental Activities of Daily Living (OARS-IADL): This measure contains six items that assess the ability to perform important tasks for daily living (e.g., Could you prepare your own meals? Could you drive a car?). Scores range from 6 to 24. Higher scores indicate increasing difficulty in engaging in daily activities." (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | -0.15 |
Placebo | -0.31 |
"Duke Older Americans Resources and Services Procedures- Instrumental Activities of Daily Living (OARS-IADL): This measure contains six items that assess the ability to perform important tasks for daily living (e.g., Could you prepare your own meals? Could you drive a car?). Scores range from 6 to 24. Higher scores indicate increasing difficulty in engaging in daily activities." (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) |
---|---|
Lidocaine | 2.46 |
Placebo | 2.1 |
To characterize cognitive function over time, while minimizing potential redundancy in the cognitive measures, a factor analysis was performed on the 14 cognitive test scores from baseline. We chose a five-factor solution, which represents 5 cognitive domains: structured verbal memory, unstructured verbal memory, executive function, visual memory and attention/concentration. Each domain score is normally distributed with a mean of zero. A change score was calculated for each domain by subtracting the baseline from the 6-week score. A dichotomous outcome variable of post-operative cognitive deficit was defined as a decline of ≥1 standard deviation in 1 or more of the 5 domains. (NCT00938964)
Timeframe: Preoperative to 6 weeks after surgery
Intervention | Participants (Count of Participants) |
---|---|
Lidocaine | 87 |
Placebo | 83 |
The Medical Outcomes Study 36-Item Short Form Health Survey (SF-36): The SF-36 was designed to measure general health status. Two scales were used: Work Activities (four items) and General Health (one item). For the work activities scale, the reported score was the sum of four questions, each with values ranging from 1 to 4, the total score could range from 4 to 16. A higher score on Work Activities indicates more health-related problems For the general health question, the patients ranked their health from Excellent (1) to poor (5), the scale ranged from 1 to 5 with 1 being best health and 5 being worst. A high score in General Health indicates poorer health state. (NCT00938964)
Timeframe: baseline, 1-year
Intervention | units on a scale (Mean) | |
---|---|---|
1 year Change Work Activities | 1 year Change General health perception | |
Lidocaine | -1.37 | -0.28 |
Placebo | -1.42 | -0.43 |
The Medical Outcomes Study 36-Item Short Form Health Survey (SF-36): The SF-36 was designed to measure general health status. Two scales were used: Work Activities (four items) and General Health (one item). For the work activities scale, the reported score was the sum of four questions, each with values ranging from 1 to 4, the total score could range from 4 to 16. A higher score on Work Activities indicates more health-related problems For the general health question, the patients ranked their health from Excellent (1) to poor (5), the scale ranged from 1 to 5 with 1 being best health and 5 being worst. A high score in General Health indicates poorer health state. (NCT00938964)
Timeframe: baseline, 6-weeks
Intervention | units on a scale (Mean) | |
---|---|---|
6-Week Change Work activities | 6-Week Change General health perception | |
Lidocaine | 2.71 | -0.004 |
Placebo | 3 | -0.03 |
Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removalime points and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal
Intervention | Mean linear fluorescence intensity-MLFI (Mean) | |||
---|---|---|---|---|
Baseline | Cross-clamp removal | End of Bypass | 6 hours post cross-clamp removal | |
Lidocaine | -0.15 | 0.02 | -0.73 | -0.10 |
Placebo | -0.43 | -0.73 | -0.40 | 0.19 |
Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removalime points and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal
Intervention | Mean linear fluorescence intensity-MLFI (Mean) | |||
---|---|---|---|---|
Baseline | Cross-clamp removal | End of Bypass | 6 hours post cross-clamp removal | |
Lidocaine | -4.22 | -2.46 | -0.34 | 1.21 |
Placebo | -0.04 | 1.83 | 2.64 | 0.54 |
Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removal and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal
Intervention | Mean linear fluorescence intensity-MLFI (Mean) | |||
---|---|---|---|---|
Baseline | Cross-clamp removal | End of Bypass | 6 hours post cross-clamp removal | |
Lidocaine | -2.02 | 0.56 | 0.58 | 1.04 |
Placebo | -0.08 | 0.17 | 1.19 | -0.68 |
Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removalime points and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal
Intervention | Mean linear fluorescence intensity-MLFI (Mean) | |||
---|---|---|---|---|
Baseline | Cross-clamp removal | End of Bypass | 6 hours post cross-clamp removal | |
Lidocaine | -0.03 | 0.03 | 0.33 | 0.37 |
Placebo | 0.35 | 0.43 | 0.05 | 0.27 |
"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes
Intervention | Intensity score (Mean) |
---|---|
Topical KeAmLi Combo | 62.7 |
Topical Ketamine | 63.1 |
Topical Amitriptyline | 69.2 |
Topical Lidocaine | 65.8 |
Topical Vehicle | 61.9 |
Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes
Intervention | mN (Mean) | |
---|---|---|
Mechanical Detection Threshold | Mechanical Pain Threshold | |
Topical Amitriptyline | 3.573423965 | 152.4768146 |
Topical KeAmLi Combo | 3.519376956 | 152.3293608 |
Topical Ketamine | 3.464204768 | 135.9 |
Topical Lidocaine | 3.546037659 | 126.9 |
Topical Vehicle | 3.525692637 | 148.7138273 |
Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes
Intervention | Degrees celsius (Mean) | |
---|---|---|
Warm Detection Threshold | Heat Pain Threshold | |
Topical Amitriptyline | 33.9 | 40.0 |
Topical KeAmLi Combo | 33.6 | 39.8 |
Topical Ketamine | 34.0 | 40.0 |
Topical Lidocaine | 33.7 | 39.4 |
Topical Vehicle | 33.8 | 39.7 |
The investigators are measuring the need for additional drug at the end of 60 minutes. (NCT01737840)
Timeframe: 60 th minute
Intervention | participants (Number) |
---|---|
Pantoprazole | 13 |
Ranitidine | 8 |
The investigators are measuring the change of pain from the baseline to the 30th and 60th minutes by visual anologue scale (VAS). Visual Analogue Scale measurement is between 0 (no pain) and 100 (worst pain). A decrease of 13 or 16 mm in VAS score is accepted as a minimum clinically significant change in pain. (NCT01737840)
Timeframe: 30th and 60th minutes
Intervention | Visual Analogue Scale (Mean) | |
---|---|---|
VAS score changes at 60 minutes | VAS scores changes at 30 minutes | |
Pantoprazole | 39.6 | 27.6 |
Ranitidine | 42.3 | 28.3 |
Bradykinesia refers to the slowness in executing a movement. Bradykinesia was assessed by measuring the time in seconds it takes to do the following sequence, 10 times: 1) hand closing and opening while squeezing a ball 2) elbow flexion 3) hand closing and opening, and 4) elbow extension. Subjects were allowed to practice these hand and arm movements until performance appeared not to get faster, and then were abstained from further practice to minimize learning effects. The time it takes subjects to execute the entire sequence 10 times with either the left or right arm/hand was measured. Means are reported for each group. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, 3 months post tDCS
Intervention | seconds (Mean) | |||
---|---|---|---|---|
Baseline | 1 day post tDCS | 1 month post tDCS | 3 months post tDCS | |
Real tDCS While Off Medication | 14.5 | 8.9 | 9.4 | 9.7 |
Real tDCS While on Medication | 12.3 | 8.5 | 9.1 | 9.0 |
Sham tDCS While Off Medication | 14.4 | 11.1 | 11.7 | 11.6 |
Sham tDCS While on Medication | 12.3 | 10.5 | 10.5 | 10.4 |
Gait speed was measured by the time it took the subject to walk 10m. Subjects were instructed to walk at a fast pace without taking the risk of falling, wearing the same shoes and using assistive devices consistently if needed. Gait speed was measured at baseline and post-tDCS. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, 3 months post-tDCS
Intervention | Seconds (Mean) | |||
---|---|---|---|---|
Baseline | One day post tDCS | One month post tDCS | Three month post tDCS | |
Real tDCS While Off Medication | 9.7 | 7.5 | 7.6 | 9.0 |
Real tDCS While on Medication | 8.7 | 7.2 | 7.0 | 7.2 |
Sham tDCS While Off Medication | 9.5 | 9.8 | 10.9 | 9.7 |
Sham tDCS While on Medication | 8.6 | 7.6 | 8.7 | 8.8 |
The Motor Unified Parkinson's Disease Rating Scale (UPDRS) includes only the motor assessment of the UPDRS (Part III) and examines speech, facial expression, tremor at rest, action tremor, rigidity, finger taps, hand movements, hand pronation and supination, leg agility, arising from chair, posture, gait, postural stability and body bradykinesia. The scores range from 0 (no motor impairment) to 108 (severe motor impairment). The Motor UPDRS was administred at baseline and at 1 day post, 1 month post, and 3 months post tDCS or sham. Subjects were assessed on medication and off medication. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, and 3 months post real and sham tDCS
Intervention | units on a scale (Mean) | |||
---|---|---|---|---|
Baseline | 1 day post tDCS | 1 month post tDCS | 3 months post tDCS | |
Real tDCS While Off Medication | 34.0 | 31.5 | 31.4 | 34.0 |
Real tDCS While on Medication | 22.2 | 20.4 | 22.7 | 23.1 |
Sham tDCS While Off Medication | 26.5 | 29.0 | 29.0 | 27.1 |
Sham tDCS While on Medication | 17.5 | 15.6 | 18.6 | 17.6 |
The Total Unified Parkinson's Disease Rating Scale (UPDRS) is an overall clinical rating scale that quantifies the signs and symptoms of Parkinson's disease. The total UPDRS score was obtained from subject examination, subject interviews and questionnaires. The UPDRS encompasses measurement of mentation, behavior, mood, activities of daily living and motor skills. The total UPDRS scores ranges from 0 (not affected) to 176 (most severely affected). The UPDRS was administred at baseline and at 1 day post, 1 month post, and 3 months post tDCS or sham, while on medication and off medication. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, 3 months post-tDCS
Intervention | units on a scale (Mean) | |||
---|---|---|---|---|
Baseline | 1 day post tDCS | 1 month post tDCS | 3 months post tDCS | |
Real tDCS While Off Medication | 58.4 | 54.1 | 56.1 | 60.1 |
Real tDCS While on Medication | 42.5 | 36.9 | 42.5 | 43.4 |
Sham tDCS While Off Medication | 53.6 | 50.4 | 54.4 | 52.4 |
Sham tDCS While on Medication | 39.5 | 32.0 | 36.1 | 35.5 |
16 reviews available for lidocaine and Acute Disease
Article | Year |
---|---|
Intranasal lidocaine for acute migraine: A meta-analysis of randomized controlled trials.
Topics: Acute Disease; Administration, Intranasal; Humans; Lidocaine; Migraine Disorders; Randomized Control | 2019 |
A case of acute pilsicainide intoxication mimicking viral encephalitis.
Topics: Acute Disease; Anti-Arrhythmia Agents; Diagnosis, Differential; Electrocardiography; Encephalitis, V | 2017 |
Intranasal lidocaine for acute migraine: A protocol for the systematic review of randomized clinical trials.
Topics: Acute Disease; Administration, Intranasal; Anesthetics, Local; Humans; Lidocaine; Migraine Disorders | 2019 |
Best BETs from the Manchester Royal Infirmary. BET 2: should intranasal lidocaine be used in patients with acute cluster headache?
Topics: Acute Disease; Administration, Intranasal; Anesthetics, Local; Cluster Headache; Evidence-Based Emer | 2013 |
Severe needle phobia in the perianesthesia setting.
Topics: Acute Disease; Adult; Ambulatory Surgical Procedures; Desensitization, Psychologic; Epilepsies, Part | 2007 |
Recent advances in acute pain management.
Topics: Acute Disease; Administration, Oral; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; | 1995 |
Lidocaine overdose: another preventable case?
Topics: Acute Disease; Administration, Topical; Drug Overdose; Humans; Infant; Infant, Newborn; Lidocaine; M | 1994 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
The management of acute coronary insufficiency.
Topics: Acute Disease; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Arteriosclerosis; Aspartate Aminotr | 1977 |
[Prognostic significance of arrhythmias in acute myocardial infarction (author's transl)].
Topics: Acute Disease; Arrhythmias, Cardiac; Coronary Care Units; Electrocardiography; Humans; Lidocaine; My | 1977 |
Should lidocaine be administered routinely to all patients after acute myocardial infarction?
Topics: Acute Disease; Age Factors; Arrhythmias, Cardiac; Coronary Care Units; Critical Care; Electrocardiog | 1978 |
Lidocaine prophylaxis in acute myocardial infarction.
Topics: Acute Disease; Double-Blind Method; Heart Rate; Humans; Lidocaine; Myocardial Infarction; Risk; Time | 1978 |
Drug metabolism in liver disease.
Topics: Acetaminophen; Acute Disease; Antipyrine; Chemical and Drug Induced Liver Injury; Chronic Disease; H | 1975 |
Lidocaine in the early phase of acute myocardial infarction: the controversy over prophylactic or selective use.
Topics: Acute Disease; Arrhythmias, Cardiac; Humans; Lidocaine; Myocardial Infarction; Time Factors; Ventric | 1990 |
Practical considerations in the management of shock complicating acute myocardial infarction. A summary of current practice.
Topics: Acute Disease; Arrhythmias, Cardiac; Atropine; Blood Pressure Determination; Central Venous Pressure | 1970 |
The prophylactic use of anti-arrhythmic drugs in acute myocardial infarction.
Topics: Acute Disease; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Death, Sud | 1973 |
51 trials available for lidocaine and Acute Disease
Article | Year |
---|---|
The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media.
Topics: Acetaminophen; Acute Disease; Analgesics; Anti-Bacterial Agents; Child; Child, Preschool; Earache; H | 2022 |
Perirenal space blocking restores gastrointestinal function in patients with severe acute pancreatitis.
Topics: Abdominal Pain; Acute Disease; Adult; Anesthetics, Local; Celiac Plexus; China; Female; Gastrointest | 2013 |
[The comparative study of the of clinical effectiveness of the Candibiotic, Otipax, and Anauran ear drops for the treatment of acute external and middle ear otitis].
Topics: Acute Disease; Administration, Topical; Adolescent; Adult; Aged; Aminopyrine; Anti-Bacterial Agents; | 2013 |
Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
Topics: Acute Disease; Aged; Anesthetics, Local; Drug Therapy, Combination; Female; Humans; Injections, Subc | 2016 |
Intranasal Lidocaine in Acute Treatment of Migraine: A Randomized Controlled Trial.
Topics: Acute Disease; Administration, Intranasal; Adult; Anesthetics, Local; Antiemetics; Double-Blind Meth | 2017 |
Shoulder acute pain in primary healthcare: is retraining effective for GP principals? SAPPHIRE--a randomized controlled trial.
Topics: Acute Disease; Adult; Aged; Anesthetics, Local; Education, Medical, Continuing; Epidemiologic Method | 2008 |
Shoulder acute pain in primary health care: is retraining GPs effective? The SAPPHIRE randomized trial: a cost-effectiveness analysis.
Topics: Acute Disease; Anesthetics, Local; Anti-Inflammatory Agents; Cortisone; Cost-Benefit Analysis; Drug | 2009 |
Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial.
Topics: Acute Disease; Administration, Intranasal; Adult; Anesthetics, Local; Anti-Infective Agents, Local; | 2009 |
Rapid relief of acute sore throat with AMC/DCBA throat lozenges: randomised controlled trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Analgesics; Analysis of Variance; Anti-Infective Agents; Dou | 2010 |
The value of clinical tests in acute full-thickness tears of the supraspinatus tendon: does a subacromial lidocaine injection help in the clinical diagnosis? A prospective study.
Topics: Acute Disease; Adult; Aged; Arthroscopy; Emergencies; Female; Humans; Lidocaine; Male; Middle Aged; | 2010 |
Glycerol lidocaine eardrops for the treatment of acute abacterial otitis externa.
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthetics, Local; Double-Blind Method; Germany; Glycerol; | 2010 |
Blockade of branches of the ophthalmic nerve in the management of acute attack of migraine.
Topics: Acute Disease; Adult; Anesthetics, Local; Epinephrine; Female; Humans; Lidocaine; Middle Aged; Migra | 2002 |
Efficacy and safety of intravenous injection of lidocaine in the treatment of acute primary angle-closure glaucoma: a pilot study.
Topics: Acute Disease; Aged; Anesthetics, Intravenous; Antihypertensive Agents; Blood Pressure; Drug Therapy | 2007 |
Topical lignocaine for pain relief in acute otitis media: results of a double-blind placebo-controlled randomised trial.
Topics: Acute Disease; Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Dou | 2008 |
Lidocaine 8 mg sore throat lozenges in the treatment of acute pharyngitis. A new therapeutic option investigated in comparison to placebo treatment.
Topics: Acute Disease; Administration, Oral; Adult; Anesthetics, Local; Area Under Curve; Double-Blind Metho | 2007 |
Epinephrine/Lidocaine injection vs. saline during endoscopic sinus surgery.
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Local; Blood Loss, Surgical | 2008 |
Drugs and the heart. VII. Which drug for which disease?
Topics: Acute Disease; Adrenergic beta-Antagonists; Angina Pectoris; Anti-Arrhythmia Agents; Antihypertensiv | 1980 |
The anal dilator in the conservative management of acute anal fissures.
Topics: Acute Disease; Adolescent; Adult; Aged; Clinical Trials as Topic; Dilatation; Female; Fissure in Ano | 1983 |
Efficacy and safety of intravenous tocainide compared with intravenous lidocaine for acute ventricular arrhythmias immediately after cardiac surgery.
Topics: Acute Disease; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Surgical Procedure | 1984 |
Mexiletine in clinical practice.
Topics: Acute Disease; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Lidoc | 1980 |
[Hemodynamic effects of lidocaine and mexiletine in acute heart infarction].
Topics: Acute Disease; Female; Hemodynamics; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial In | 1982 |
A double-blind trial comparing subacromial methylprednisolone and lignocaine in acute rotator cuff tendinitis.
Topics: Acute Disease; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Huma | 1993 |
Comparison of intra-articular lignocaine and a suprascapular nerve block for acute anterior shoulder dislocation.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Fe | 1997 |
Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy?
Topics: Acute Disease; Administration, Rectal; Administration, Topical; Adult; Anal Canal; Anesthetics, Loca | 1997 |
Preemptive analgesia in patients undergoing appendectomy.
Topics: Acute Disease; Adolescent; Adult; Analgesia; Anesthetics, Local; Appendicitis; Bupivacaine; Double-B | 1997 |
Treatment of acute supraspinatus tendinitis: physiotherapy or steroid injection?
Topics: Acute Disease; Adult; Anesthetics, Local; Anti-Inflammatory Agents; Humans; Lidocaine; Methylprednis | 1997 |
Intra-articular lignocaine versus Entonox for reduction of acute anterior shoulder dislocation.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Local; Female; | 1999 |
Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine.
Topics: Acute Disease; Administration, Topical; Adult; Female; Hemorrhoids; Humans; Lidocaine; Male; Middle | 2001 |
Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster.
Topics: Acute Disease; Administration, Cutaneous; Administration, Topical; Adult; Aged; Aged, 80 and over; A | 2002 |
Anti-dysrhythmic treatment in acute myocardial infarction.
Topics: Acute Disease; Administration, Oral; Atenolol; Clinical Trials as Topic; Disopyramide; Double-Blind | 1979 |
Lidocaine and the quarternary ammonium compound QX-572 in acute myocardial infarction. A comparative study.
Topics: Acute Disease; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; | 1978 |
Lidocaine prophylaxis in acute myocardial infarction.
Topics: Acute Disease; Double-Blind Method; Heart Rate; Humans; Lidocaine; Myocardial Infarction; Risk; Time | 1978 |
Suppression of ventricular arrhythmias with intravenous disopyramide and lidocaine: efficacy comparison in a randomized trial.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Humans; Injections | 1979 |
[Treatment of acute rheumatic diseases with Probaphen in private medicine].
Topics: Acetaminophen; Acute Disease; Aminopyrine; Clinical Trials as Topic; Dipyrone; Drug Combinations; Dr | 1976 |
Editorial: Lidocaine: prophylactic value in myocardial infarction.
Topics: Acute Disease; Adult; Clinical Trials as Topic; Female; Humans; Injections, Intramuscular; Injection | 1975 |
A controlled trial of intramuscular lidocaine in the prevention of premature ventricular contractions associated with acute myocardial infarction.
Topics: Acute Disease; Arrhythmias, Cardiac; Blood Pressure; Female; Heart Ventricles; Humans; Injections, I | 1976 |
Is intravenous lidocaine clinically effective in acute migraine?
Topics: Acute Disease; Adult; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; | 1991 |
The emergency department treatment of dyspepsia with antacids and oral lidocaine.
Topics: Acute Disease; Aluminum Hydroxide; Antacids; Drug Combinations; Drug Therapy, Combination; Dyspepsia | 1990 |
Treatment of first episodes of acute anal fissure: prospective randomised study of lignocaine ointment versus hydrocortisone ointment or warm sitz baths plus bran.
Topics: Acute Disease; Adult; Baths; Clinical Trials as Topic; Dietary Fiber; Female; Fissure in Ano; Humans | 1986 |
Postoperative analgesia induced by subarachnoid lidocaine plus calcitonin.
Topics: Acute Disease; Analgesia; Calcitonin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; | 1987 |
Lignocaine given prophylactically to patients with acute myocardial infarction.
Topics: Acute Disease; Arrhythmias, Cardiac; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans | 1971 |
[Clinical experiments with a new derivative of 6-aminopenicillanic acid: hetacillin potassium].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Ampicillin; Anti-Bacterial Agents; Bacterial Infec | 1972 |
[Lidocaine in ventricular tachycardia caused by acute myocardial infarct].
Topics: Acute Disease; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Heart Ventricles; Humans; Li | 1974 |
Prophylactic lignocaine in hospitalized patients with acute myocardial infarction.
Topics: Acute Disease; Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Lidocaine; Myocardial Infarct | 1973 |
A double-blind trial of lidocaine in acute myocardial infarction.
Topics: Acute Disease; Age Factors; Arrhythmias, Cardiac; Clinical Trials as Topic; Female; Humans; Lidocain | 1973 |
Propranolol in the treatment of acute myocardial infarction. Effect on myocardial oxygenation and hemodynamics.
Topics: Acute Disease; Adult; Aged; Blood Pressure; Cardiac Catheterization; Cardiac Output; Clinical Trials | 1974 |
Anti-ischemic effect of lidocain in the acute state of myocardial infarction.
Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Injections, I | 1973 |
Antiarrhythmic prophylaxis with procainamide in acute myocardial infarction.
Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Blood Pressure; Clinical Trials as Topic; Electrocardiogr | 1969 |
Prophylaxis of ventricular dysrhythmias following acute myocardial infarction: a double-blind trial of continuous intravenous infusion of lignocaine.
Topics: Acute Disease; Arrhythmias, Cardiac; Clinical Trials as Topic; Female; Humans; Injections, Intraveno | 1971 |
Lignocaine therapy for ventricular ectopic activity after acute myocardial infarction: a double-blind trial.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Gas Analysis; Clinical Trials as Topic; Elec | 1971 |
Antiarrhythmic prophylaxis in acute myocardial infarction.
Topics: Acute Disease; Administration, Oral; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Care U | 1971 |
177 other studies available for lidocaine and Acute Disease
Article | Year |
---|---|
Efficacy of intra-arterial lidocaine infusion in the treatment of cerulein-induced acute pancreatitis.
Topics: Acute Disease; Animals; Ceruletide; Infusions, Intra-Arterial; Lidocaine; Pancreas; Pancreatitis; Ra | 2020 |
Greater palatine block in the treatment of acute epistaxis.
Topics: Acute Disease; Anesthetics, Local; Cautery; Epinephrine; Epistaxis; Humans; Injections; Lidocaine; P | 2015 |
Hoigne syndrome: a little-known adverse effect of lidocaine.
Topics: Acute Disease; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Syndrome; Young | 2016 |
A new endovascular strategy utilizing a hybrid procedure for long segmental occlusion by acute arterial thromboembolism in the lower extremity.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Computed Tomography Angiography; | 2016 |
Is topical lignocaine for pain relief in acute otitis media really effective?
Topics: Acute Disease; Administration, Topical; Anesthetics, Local; Child; Humans; Lidocaine; Otitis Media; | 2008 |
Lipopolysaccharide-induced hypotension is mediated by a neural pathway involving the vagus nerve, the nucleus tractus solitarius and alpha-adrenergic receptors in the preoptic anterior hypothalamic area.
Topics: Acute Disease; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Hypotension; Lidocaine; Li | 2008 |
A lacrimal sac abscess incision and drainage technique.
Topics: Abscess; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, | 2008 |
Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures.
Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography | 2009 |
[Convulsions in the operating room in a man with AIDS].
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; AIDS-Related Opportunistic Infections; Anti-HIV A | 2009 |
[Acute transient ataxia caused by local lidocaine injection during insertion of a pleural catheter].
Topics: Acute Disease; Anesthetics, Local; Catheterization; Cerebellar Ataxia; Community-Acquired Infections | 2009 |
[Acute bilateral palpebral necrosis: a rare complication of local anaesthesia].
Topics: Acute Disease; Adolescent; Anesthetics, Local; Chalazion; Corneal Ulcer; Epinephrine; Eyelid Disease | 2010 |
[Acute bilateral palpebral necrosis: a rare complication of local anaesthesia].
Topics: Acute Disease; Adolescent; Anesthetics, Local; Chalazion; Corneal Ulcer; Epinephrine; Eyelid Disease | 2010 |
[Acute bilateral palpebral necrosis: a rare complication of local anaesthesia].
Topics: Acute Disease; Adolescent; Anesthetics, Local; Chalazion; Corneal Ulcer; Epinephrine; Eyelid Disease | 2010 |
[Acute bilateral palpebral necrosis: a rare complication of local anaesthesia].
Topics: Acute Disease; Adolescent; Anesthetics, Local; Chalazion; Corneal Ulcer; Epinephrine; Eyelid Disease | 2010 |
Acute bilateral retinal hemorrhages and unilateral sixth cranial nerve palsy after inadvertent epidural anaesthetic injection and subsequent dural puncture.
Topics: Abducens Nerve Diseases; Acute Disease; Analgesia, Epidural; Anesthetics, Local; Diplopia; Female; F | 2010 |
Epidural analgesia provides better pain management after live liver donation: a retrospective study.
Topics: Acute Disease; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesth | 2011 |
Successful thrombolysis and spasmolysis of acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets.
Topics: Acute Disease; Adult; Alprostadil; Anesthetics, Local; Anti-Anxiety Agents; Fibrinolytic Agents; Flu | 2011 |
Acute bullous irritant contact dermatitis caused by EMLA® cream.
Topics: Acute Disease; Anesthetics, Local; Blister; Dermatitis, Irritant; Drug Hypersensitivity; Eczema; Emo | 2011 |
Acute lumbar spondylolysis in intercollegiate athletes.
Topics: Acute Disease; Athletes; Athletic Injuries; Bone Screws; Disability Evaluation; Female; Humans; Inje | 2012 |
[Estimation of efficacy of Hexalyse used for the treatment of acute pharyngitis].
Topics: Acute Disease; Adult; Anesthetics, Local; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Stero | 2011 |
Problems related to epidural analgesia for postoperative pain control.
Topics: Acute Disease; Adult; Aged; Amides; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Catheteri | 2002 |
Acute pancreatitis possible initial triggering mechanism and prophylaxis.
Topics: Acute Disease; Anesthetics, Local; Animals; Disease Models, Animal; Duodenum; Lidocaine; Male; Pancr | 2003 |
[Use of the drug otipax in acute otitis media in newborns and infants].
Topics: Acute Disease; Age Factors; Aminopyrine; Drug Combinations; Female; Humans; Infant; Infant, Newborn; | 2004 |
Mexiletine protects myocardium during acute ischemia by opening sarcolemmal K-ATP channel: studies in closed-chest acute ischemia model in rabbits.
Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; ATP-Binding Cassette Transporters; Disease Models, A | 2004 |
Experimental acute lung injury. Effects of methylprednisolone and lidocaine on histopathology and neutrophils.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Chemotaxis, Leukocyte; Hydrochloric Acid; Lidocain | 2004 |
Plain talk about wound pain.
Topics: Acute Disease; Anesthetics, Local; Attitude to Health; Chronic Disease; Humans; Lidocaine; Nursing A | 2005 |
Transdermal Lidoderm for acute headache?
Topics: Acute Disease; Administration, Cutaneous; Anesthetics, Local; Headache; Humans; Lidocaine | 2006 |
Acute parotiditis and facial nerve palsy--unusual side effects of Xylocaine spray.
Topics: Acute Disease; Anesthetics, Local; Dyspepsia; Endoscopy, Digestive System; Facial Paralysis; Female; | 2007 |
Superior laryngeal neuralgia after acute laryngitis and treatment with a single injection of a local anesthetic.
Topics: Acute Disease; Adult; Anesthetics, Local; Epinephrine; Humans; Injections; Laryngeal Nerves; Laryngi | 2007 |
Local anesthetic treatment significantly attenuates acute pain responding but does not prevent the neonatal injury-induced reduction in adult spinal behavioral plasticity.
Topics: Acute Disease; Anesthetics, Local; Animals; Animals, Newborn; Behavior, Animal; Electroshock; Inject | 2007 |
Interleukin-8 is increased in gingival crevicular fluid from patients with acute pulpitis.
Topics: Acute Disease; Adult; Anesthetics, Local; Female; Gingival Crevicular Fluid; Humans; Interleukin-8; | 2008 |
[Allergic contact dermatitis from lidocaine in ear drops].
Topics: Acute Disease; Aged; Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Ear; Face; Hu | 2008 |
[Treatment of acute myocardial infarction].
Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Humans; Hyaluronoglucosaminidase; | 1980 |
[Therapeutic and preventive effect of oral lidocaine in extrasystole].
Topics: Acute Disease; Administration, Oral; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Dru | 1982 |
Paranoid psychosis induced by tocainide.
Topics: Acute Disease; Anti-Arrhythmia Agents; Humans; Lidocaine; Male; Middle Aged; Paranoid Disorders; Tim | 1984 |
[Use of lidocaine peridural anesthesia in patients in the acute phase of a myocardial infarct].
Topics: Acute Disease; Aged; Anesthesia, Epidural; Blood Pressure; Cardiac Output; Female; Heart Rate; Human | 1984 |
[Prophylaxis of primary ventricular fibrillation in the acute phase of acute myocardial infarct].
Topics: Acute Disease; Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1984 |
Respiratory obstruction following vocal cord injection of Teflon paste.
Topics: Acute Disease; Airway Obstruction; Humans; Lidocaine; Male; Middle Aged; Polytetrafluoroethylene; Po | 1984 |
[Clinical usefulness of celiac plexus block].
Topics: Acute Disease; Autonomic Nerve Block; Celiac Plexus; Humans; Intestinal Obstruction; Intestinal Pseu | 1984 |
Saliva concentrations of lignocaine in patients with acute myocardial ischaemia.
Topics: Acute Disease; Adult; Aged; Coronary Disease; Humans; Lidocaine; Male; Middle Aged; Saliva; Time Fac | 1983 |
Protective effect of lidocaine in acute cerebral ischemia induced by air embolism.
Topics: Acute Disease; Animals; Brain; Brain Ischemia; Cats; Embolism, Air; Evoked Potentials, Somatosensory | 1984 |
[Intensive monitoring ward for coronary patients].
Topics: Acute Disease; Coronary Care Units; Hospitalization; Humans; Lidocaine; Monitoring, Physiologic; Myo | 1984 |
Acute pulmonary edema after regional anesthesia with lidocaine and epinephrine in a patient with chronic renal failure.
Topics: Acute Disease; Adult; Anesthesia, Conduction; Epinephrine; Humans; Kidney Failure, Chronic; Lidocain | 1984 |
A simple method of treatment for the acute headache.
Topics: Acute Disease; Headache; Humans; Injections, Intravenous; Lidocaine; Procaine | 1984 |
[The immediate treatment of acute myocardial infarct].
Topics: Acute Disease; Arrhythmias, Cardiac; First Aid; Furosemide; Hemodynamics; Humans; Isosorbide Dinitra | 1981 |
Should prophylactic antiarrhythmic drug therapy be used in acute myocardial infarction?
Topics: Acute Disease; Humans; Lidocaine; Metabolism; Methods; Myocardial Infarction; Time Factors; Ventricu | 1982 |
[Emergency therapy of cardiac arrhythmias. Statistico-clinical evaluation of verapamil (clinical note)].
Topics: Acute Disease; Adult; Aged; Ajmaline; Arrhythmias, Cardiac; Bunaftine; Female; Humans; Lidocaine; Ma | 1982 |
[The place of lidocaine in the treatment of acute attacks of intracranial hypertension].
Topics: Acute Disease; Adult; Aged; Female; Humans; Intracranial Pressure; Lidocaine; Male; Middle Aged; Pse | 1982 |
[Standard therapy of acute myocardial infarction.--I: General management (author's transl)].
Topics: Acute Disease; Analgesics; Arrhythmias, Cardiac; Coronary Care Units; Early Ambulation; Hemodynamics | 1981 |
The effects of lidocaine on intracellular and extracellular potentials, activation, and ventricular arrhythmias during acute regional ischemia in the isolated porcine heart.
Topics: Action Potentials; Acute Disease; Animals; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Corona | 1981 |
[Anti-arrhythmia effect of flecainide in acute myocardial infarct in comparison with lidocaine].
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Dogs; Flecainide; Lidocaine; Myocardial Infarction; Pi | 1981 |
Recurrence of ventricular fibrillation in acute ischemic heart disease.
Topics: Acute Disease; Anti-Arrhythmia Agents; Coronary Disease; Female; Heart Arrest; Humans; Lidocaine; Ma | 1981 |
Improved observational method for studying therapeutic efficacy. Suggestive evidence that lidocaine prophylaxis prevents death in acute myocardial infarction.
Topics: Acute Disease; Aged; Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Lidocaine; Male; | 1981 |
[Treatment of peripheral lesions of the facial nerve with a lidocaine block].
Topics: Acute Disease; Adolescent; Adult; Cervical Plexus; Facial Nerve; Facial Neuralgia; Facial Paralysis; | 1980 |
[Dangerous bradycardia after xylocaine treatment of acute myocardial infarct].
Topics: Acute Disease; Bradycardia; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction | 1980 |
[Intramuscular administration of lignocaine for prevention of life-threatening arrhythmia in acute myocardial infarct].
Topics: Acute Disease; Adult; Aged; Female; Humans; Injections, Intramuscular; Lidocaine; Male; Middle Aged; | 1980 |
First-aid treatment for acute coronary thrombosis.
Topics: Acute Disease; Coronary Disease; Digoxin; Humans; Lidocaine; Tachycardia; Ventricular Fibrillation | 1980 |
Postpartum acute subdural hematoma; a probable complication of saddle block analgesia.
Topics: Acute Disease; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Female; Hematoma, Subdural; Human | 1980 |
The treatment of acute myocardial infarction.
Topics: Acute Disease; Atropine; Bradycardia; Humans; Lidocaine; Myocardial Infarction; Surveys and Question | 1980 |
[Drug metabolism in patients with liver disease (author's transl)].
Topics: Acute Disease; Adult; Antipyrine; Biological Availability; Biotransformation; Cholestasis; Female; H | 1980 |
Facilitation of reentry by lidocaine in canine myocardial infarction.
Topics: Acute Disease; Animals; Chronic Disease; Dogs; Electrocardiography; Electrophysiology; Heart Conduct | 1994 |
Effect of vasoconstrictive agents added to lidocaine on intravenous lidocaine-induced convulsions in rats.
Topics: Acute Disease; Animals; Blood Gas Analysis; Blood Glucose; Blood Pressure; Dose-Response Relationshi | 1995 |
Treatment of the cutaneous pain of acute herpes zoster with 9% lidocaine (base) in petrolatum/paraffin ointment.
Topics: Acute Disease; Administration, Cutaneous; Adult; Drug Evaluation; Female; Herpes Zoster; Humans; Lid | 1994 |
Ischemia enhances use-dependent sodium channel blockade by pilsicainide, a class IC antiarrhythmic agent.
Topics: Acute Disease; Aged; Analysis of Variance; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chi-Square | 1994 |
Advantages and limitations of metaanalytic regressions of clinical trials data.
Topics: Acute Disease; Confounding Factors, Epidemiologic; Crohn Disease; Humans; Immunosuppression Therapy; | 1994 |
A prospective study for validation of Bayesian prediction approach to adjust individual lidocaine dosage.
Topics: Acute Disease; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Bayes Theorem; Female; Humans; Infusio | 1994 |
Lidocaine and acute coronary care.
Topics: Acute Disease; Arrhythmias, Cardiac; Coronary Care Units; Humans; Lidocaine | 1993 |
Cortical facilitatory action on centralis lateralis thalamic activity during the development of carrageenin-produced inflammation.
Topics: Acute Disease; Afferent Pathways; Anesthetics, Local; Animals; Carrageenan; Chronic Disease; Edema; | 1996 |
Intranasal lidocaine for treatment of migraine.
Topics: Acute Disease; Administration, Intranasal; Humans; Lidocaine; Migraine Disorders | 1996 |
Intranasal lidocaine for treatment of migraine.
Topics: Acute Disease; Diagnosis, Differential; Humans; Lidocaine; Migraine Disorders; Tomography, X-Ray Com | 1996 |
Intranasal lidocaine for treatment of migraine.
Topics: Acute Disease; Administration, Intranasal; Humans; Lidocaine; Migraine Disorders | 1996 |
Intranasal lidocaine for treatment of migraine.
Topics: Acute Disease; Administration, Inhalation; Humans; Lidocaine; Migraine Disorders | 1996 |
Sphenopalatine ganglion block: a safe and easy method for the management of orofacial pain.
Topics: Acute Disease; Administration, Intranasal; Anesthetics, Local; Autonomic Nerve Block; Chronic Diseas | 1995 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
[Perioperative management for acute abdominal aortic obstruction in a patient with acute myocardial reinfarction associated with acute renal failure].
Topics: Acute Disease; Acute Kidney Injury; Aged; Anesthesia, General; Anesthetics, Combined; Aorta, Abdomin | 1997 |
Tumescent infiltration of corticosteroids, lidocaine, and epinephrine into dermatomes of acute herpetic pain or postherpetic neuralgia.
Topics: Acute Disease; Anesthetics, Local; Epinephrine; Glucocorticoids; Herpes Zoster; Humans; Injections; | 1998 |
Hypotension following acute hypovolaemia depends on the caudal midline medulla.
Topics: Acute Disease; Anesthetics, Local; Animals; Blood Pressure; Cobalt; Hemorrhage; Hypotension; Lidocai | 1998 |
Cellular mechanisms underlying spontaneous interictal spikes in an acute model of focal cortical epileptogenesis.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Acute Disease; | 1999 |
Sight-threatening acute orbital swelling from peribulbar local anesthesia.
Topics: Acute Disease; Aged; Anesthetics, Local; Drug Hypersensitivity; Edema; Female; Follow-Up Studies; Gl | 1999 |
[The patient with back pain and the family physician. Problem solving with simple methods].
Topics: Acute Disease; Anesthetics, Local; Back Pain; Chiropractic; Humans; Lidocaine; Male; Manipulation, S | 1999 |
Central retinal artery occlusion after a local anesthetic with adrenaline on nasal mucosa.
Topics: Acute Disease; Aged; Anesthetics, Local; Blindness; Drug Combinations; Epinephrine; Humans; Lacrimal | 2000 |
The influence of lidocaine on the permeability of the blood-cerebrospinal fluid barrier in experimental acute hypercapnia in the rabbit.
Topics: Acute Disease; Anesthetics, Local; Animals; Anti-Bacterial Agents; Blood Pressure; Blood-Brain Barri | 2001 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Intra-articular lidocaine for acute anterior shoulder dislocation reduction.
Topics: Acute Disease; Anesthetics, Local; Evidence-Based Medicine; Humans; Injections, Intra-Articular; Lid | 2002 |
Intrathecal lidocaine prevents cardiovascular collapse and neurogenic pulmonary edema in a rat model of acute intracranial hypertension.
Topics: Acute Disease; Anesthetics, Local; Animals; Blood Pressure; Brain; Electrocardiography; Heart Rate; | 2002 |
[Emergencies in the practice. Acute lumbago: diagnosis and therapy].
Topics: Acute Disease; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents; Chiropractic; Diagn | 2002 |
Temporary bilateral blindness after acute lidocaine toxicity.
Topics: Acute Disease; Adult; Anesthetics, Local; Blindness; Female; Fractures, Bone; GABA Modulators; Hand | 2002 |
Negative inotropic effect of lidocaine in patients with coronary arterial disease and normal subjects.
Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Angina Pectoris; Coronary Disease; Depression, Ch | 1977 |
The use of buffered lignocaine solution in the presence of acute inflammation.
Topics: Acute Disease; Anesthesia, Dental; Anesthesia, Local; Buffers; Humans; Hydrogen-Ion Concentration; L | 1977 |
[Effectiveness and comparative evaluation of various means of arrhythmia prophylaxis in acute period of myocardial infarction].
Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Female; Humans; Lidocaine; Male; M | 1979 |
[The treatment of acute cardiac dysrhythmias with atenolol (Tenormin) particularly after myocardial infarction (author's transl)].
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Atenolol; Atrial Fibrillation; Atrial Flutter; Car | 1978 |
Rapid and accurate diagnosis of acute cholecystitis with 99mTc-HIDA cholescintigraphy.
Topics: Acetates; Acute Disease; Adult; Cholecystitis; Cholelithiasis; Cystic Duct; Diagnosis, Differential; | 1979 |
Relieving pain with nerve blocks.
Topics: Acute Disease; Aged; Back Pain; Bursitis; Humans; Intervertebral Disc; Joint Diseases; Lidocaine; Mi | 1978 |
[Pharmacological treatment of arrhythmia following acute myocardial infarct].
Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bretylium Compounds; Humans; Lidoc | 1975 |
[Myocardial infarct in the municipal hospital. Report on 1087 cases].
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Creatine Kinase; Exercise Test; Female; Hemodynami | 1977 |
[Pharmacokinetics of lidocaine after intramuscular injection in patients with acute myocardial infarction (author's transl)].
Topics: Acute Disease; Arrhythmias, Cardiac; Half-Life; Humans; Injections, Intramuscular; Lidocaine; Myocar | 1979 |
Premature ventricular contractions in acute myocardial infarction. Correlation between their origin and the location of infarction.
Topics: Acute Disease; Arrhythmias, Cardiac; Electrocardiography; Humans; Lidocaine; Myocardial Infarction | 1979 |
[Lidocaine pharmacokinetics and substantiation of the new method of its administration in myocardial infarct].
Topics: Acute Disease; Adult; Aged; Biological Availability; Female; Humans; Infusions, Parenteral; Isotonic | 1979 |
[Preventive effectiveness of verapamil in ventricular fibrillation in the first 24 hours after myocardial infarct].
Topics: Acute Disease; Adult; Aged; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Ven | 1979 |
[Arrhythmias during catheterization of patients with acute myocardial infarction (author's transl)].
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Cardiac Catheterization; Female; Humans; Lidocaine | 1977 |
Xylocaine treatment in experimental pancreatitis in pigs.
Topics: Acute Disease; Animals; Drug Evaluation, Preclinical; Hemorrhage; Infusions, Parenteral; Lidocaine; | 1978 |
[Current viewpoints on prevention and treatment of ventricular fibrillation in acute heart infarct].
Topics: Acute Disease; Digoxin; Drug Therapy, Combination; Electric Countershock; Humans; Lidocaine; Myocard | 1978 |
[Primary ventricular fibrillation during the acute phase of myocardial infarction (author's transl)].
Topics: Acute Disease; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Humans; Lidocaine; Middle Aged; Myo | 1978 |
[Stosstherapy with steroid-containing combination preparation "Ambene" in the acute stages of rheumatic diseases].
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aluminum; Aminopyrine; Anti-Inflammato | 1975 |
Restricted lignocaine prophylaxis in acute myocardial infarction.
Topics: Acute Disease; Adult; Aged; Coronary Care Units; Humans; Lidocaine; Male; Middle Aged; Myocardial In | 1977 |
[Lidocaine in acute myocardial infarction].
Topics: Acute Disease; Humans; Lidocaine; Myocardial Infarction | 1977 |
Ventricular fibrillation and acute myocardial infarction.
Topics: Acute Disease; Adult; Aged; Electric Countershock; Humans; Lidocaine; Middle Aged; Myocardial Infarc | 1977 |
Acute myocardial infarction in an American traveler in China.
Topics: Acute Disease; Adult; China; Emergency Medical Services; Heart Arrest; Humans; Infusions, Parenteral | 1976 |
Comparative effects of lidocaine and procainamide on acutely impaired hemodynamics.
Topics: Acute Disease; Adult; Aged; Blood Pressure; Cardiac Output; Depression, Chemical; Electrocardiograph | 1976 |
Influence of viral hepatitis on the disposition of two compounds with high hepatic clearance: lidocaine and indocyanine green.
Topics: Acute Disease; Adult; Half-Life; Hepatitis A; Humans; Indocyanine Green; Kinetics; Lidocaine; Liver; | 1976 |
Significance of ventricular premature beats as a potential life threatening arrhythmia in acute myocardial infarction.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Humans; Lidocaine; Middle Aged; Myocardial Infarct | 1976 |
[Lidocaine therapy in the early phase of arrhythmia after acute myocardial infarct without influence on the fibrillatory threshold and on the spontaneous ventricular fibrillation of the heart].
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Dogs; Lidocaine; Myocardial Infarction; Time Factors; | 1976 |
[Clinical and experimental contribution to the pathogenesis of acute life-threatening incidents following neck anesthesia].
Topics: Acute Disease; Anaphylaxis; Anesthesia, Epidural; Anesthesia, Local; Anesthetics; Drug Hypersensitiv | 1975 |
[Editorial: Prevention of fatal arrhythmia].
Topics: Acute Disease; Arrhythmias, Cardiac; Humans; Lidocaine; Myocardial Infarction | 1975 |
Pharmacological modification of arrhythmias after experimentally induced acute myocardial infarction. Drugs acting on the nervous system.
Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Chlordiaz | 1975 |
[Letter: The value of preventive lidocaine therapy in acute myocardial infarct].
Topics: Acute Disease; Humans; Lidocaine; Myocardial Infarction | 1975 |
[Effect of mesocaine on the heart conduction system in acute myocardial infarct].
Topics: Acute Disease; Adult; Aged; Female; Heart Conduction System; Heart Rate; Humans; Lidocaine; Male; Mi | 1975 |
[Possibilities of a routine prevention of arrhythmia in the early phase of acute myocardial infarct].
Topics: Acute Disease; Arrhythmias, Cardiac; Heart Block; Humans; Injections, Intravenous; Lidocaine; Myocar | 1975 |
The management of acute myocardial infarction.
Topics: Acute Disease; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Glycosides; Humans; Lidocaine | 1975 |
Routine prophylactic lidocaine administration in acute myocardial infarction. An idea whose time is all but gone?
Topics: Acute Disease; Cardiology; Humans; Lidocaine; Myocardial Infarction | 1992 |
Predictive performance of Bayesian and nonlinear least-squares regression programs for lidocaine.
Topics: Acute Disease; Arrhythmias, Cardiac; Bayes Theorem; Chronic Disease; Humans; Least-Squares Analysis; | 1992 |
Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias.
Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Chronic Disease; Female; Heart Ventricles; Humans; Infusi | 1992 |
Treatment for herpes zoster ophthalmicus: stellate ganglion block as a treatment for acute pain and prevention of postherpetic neuralgia.
Topics: Acute Disease; Aged; Aged, 80 and over; Autonomic Nerve Block; Bupivacaine; Female; Herpes Zoster Op | 1991 |
Acute MI management in the 1990s.
Topics: Acute Disease; Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Angiotensin-Converting E | 1990 |
Effects of acute hypermagnesemia on the threshold for lidocaine-induced seizures in the rat.
Topics: Acute Disease; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; | 1991 |
Medical treatment of acute spinal cord injuries.
Topics: Acute Disease; Animals; Cats; Female; Lidocaine; Male; Naloxone; Spinal Cord Injuries; Thyrotropin-R | 1990 |
Contact sensitivity to lignocaine and prilocaine.
Topics: Acute Disease; Administration, Topical; Adult; Cross Reactions; Dermatitis, Contact; Drug Eruptions; | 1990 |
[Use of sacral anesthesia, prolonged by opiates, in patients with acute proctologic diseases].
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, Caudal; Anesthesia, Epidural; Anus Diseases; Fem | 1989 |
[Transient acute respiratory failure and thoracic epidural anesthesia].
Topics: Acute Disease; Anesthesia, Epidural; Bupivacaine; Female; Fentanyl; Horner Syndrome; Humans; Intraop | 1989 |
The pharmacokinetics of R- and S-tocainide in patients with acute ventricular arrhythmias.
Topics: Acute Disease; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Humans; Kinetics; Lidocai | 1986 |
[Inhalation of lidocaine in pulmonology].
Topics: Acute Disease; Administration, Inhalation; Adult; Bronchitis; Cough; Dyspnea; Female; Humans; Hyperv | 1988 |
Reduction of experimental intracranial hypertension by lidocaine.
Topics: Acute Disease; Animals; Blood Pressure; Brain Ischemia; Cats; Embolism, Air; Female; Infusions, Intr | 1987 |
Treatment of an acute anterior disk displacement in the temporomandibular joint. A case report.
Topics: Acute Disease; Aged; Dexamethasone; Female; Humans; Iontophoresis; Lidocaine; Physical Therapy Modal | 1987 |
Changes in lignocaine disposition during long-term infusion in patients with acute ventricular arrhythmias.
Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Bayes Theorem; Female; Humans; Lidocaine; Male; Metabolic | 1987 |
[Prevention, using alpha-tocopherol and lidocaine, of damage to the monooxygenase system activity and ultrastructure of hepatocytes following acute ischemia of the liver].
Topics: Acute Disease; Animals; Ischemia; Lidocaine; Liver; Male; Oxygenases; Rats; Vitamin E | 1987 |
[Drugs in acute heart disease. 1].
Topics: Acute Disease; Epinephrine; Heart Diseases; Humans; Lidocaine | 1985 |
Anesthesia for acute epiglottitis.
Topics: Acute Disease; Anesthesia; Child, Preschool; Epiglottitis; Humans; Intubation, Intratracheal; Laryng | 1986 |
Workshop II: Cost containment issues in acute myocardial infarction and coronary care management--points of view.
Topics: Acute Disease; Arrhythmias, Cardiac; Coronary Care Units; Cost Control; Health Workforce; Heart Fail | 1985 |
Acute calcification in the fingers.
Topics: Acute Disease; Calcinosis; Female; Finger Joint; Humans; Lidocaine; Middle Aged; Radiography; Splint | 1985 |
A treatment of herpes zoster.
Topics: Acute Disease; Adolescent; Adult; Aged; Autonomic Nerve Block; Female; Herpes Zoster; Humans; Lidoca | 1985 |
Acute phase of myocardial infarction.
Topics: Acute Disease; Adult; Age Factors; Aged; Arrhythmias, Cardiac; Atropine; Cardiac Complexes, Prematur | 1971 |
Initial metabolic and hormonal response to acute myocardial infarction.
Topics: Acute Disease; Adult; Aged; Blood Glucose; Blood Specimen Collection; Catecholamines; Cholesterol; C | 1974 |
[Arrhythmias in acute myocardial infarct].
Topics: Acidosis; Acute Disease; Arrhythmias, Cardiac; Aspartic Acid; Atrial Fibrillation; Atrial Flutter; B | 1973 |
[Combined drug therapy in highly acute attacks of pain in the course of rheumatic diseases].
Topics: Acute Disease; Aminopyrine; Arthritis, Rheumatoid; Dexamethasone; Drug Combinations; Female; Humans; | 1974 |
Amours M d',+AMOURS M: [Treatment of acute lumbalgia].
Topics: Acute Disease; Back Pain; Drug Synergism; Female; Humans; Hydrocortisone; Injections; Intervertebral | 1969 |
Management of acute myocardial infarction.
Topics: Acute Disease; Arkansas; Arrhythmias, Cardiac; Coronary Care Units; Heart Block; Humans; Hypotension | 1971 |
[Respiratory effects of bone cement with a methyl-methacrylate basis (author's transl)].
Topics: Action Potentials; Acute Disease; Animals; Apnea; Bone Cements; Bronchodilator Agents; Dogs; Dose-Re | 1974 |
Comparison of the effect of propranolol, lignocaine, and other drugs on normal and raised intraocular pressure in man.
Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesthetics, Local; C | 1971 |
Effects of a long-acting antiarrhythmic agent--QX-572--on therapy resistant ventricular tachyarrhythmias.
Topics: Acute Disease; Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; | 1974 |
[Hemodynamic effects of xylocaine and ajmaline in myocardial infarction].
Topics: Acute Disease; Adult; Aged; Ajmaline; Cardiac Output; Central Venous Pressure; Heart Rate; Humans; L | 1972 |
Acute sodium fluoride poisoning.
Topics: Acute Disease; Adult; Calcium; Diazepam; Diuretics; Electric Countershock; Esophageal Stenosis; Fluo | 1972 |
Pre-hospital management of acute myocardial infarction.
Topics: Acute Disease; Anxiety; Atropine; Communication; Heart Massage; Heparin; Home Care Services; Humans; | 1973 |
[Anti-arrhythmia agents. Prehospital therapy and prevention of arrhythmia in acute myocardial infarct. What advice should the general practitioner get?].
Topics: Acute Disease; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Emergency Medical Services; F | 1973 |
Experimental acute myocardial infarction. Characterization and treatment of the malignant premature ventricular contraction.
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Atropine; Coronary Vessels; Dogs; Injections, Intraven | 1973 |
Acute myocardial infarction occurring during continuous ECG recording.
Topics: Acute Disease; Alanine Transaminase; Arrhythmias, Cardiac; Aspartate Aminotransferases; Coronary Car | 1973 |
Blood lidocaine levels and kinetics following high-dose intramuscular administration.
Topics: Acute Disease; Adult; Aged; Arm; Buttocks; Humans; Injections, Intramuscular; Kinetics; Lidocaine; M | 1973 |
[Use of xylocaine in the prevention and treatment of arrhythmias during an acute myocardial infarct].
Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Injections, Intraven | 1973 |
Treatment of pain: organization of a pain clinic: treatment of acute herpes zoster.
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, Conduction; Child; Follow-Up Studies; Ganglia, A | 1973 |
[Anti-ischemic effect of lidocaine in the acute phase of myocardial infarct without shock].
Topics: Acute Disease; Adult; Aged; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction | 1974 |
Serum enzyme values following intramuscular administration of lidocaine.
Topics: Acute Disease; Adult; Alanine Transaminase; Arrhythmias, Cardiac; Aspartate Aminotransferases; Creat | 1974 |
Multiple episodes of ventricular fibrillation in acute myocardial infarction.
Topics: Acute Disease; Electric Countershock; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; P | 1972 |
Lidocaine in obstructive pulmonary disease.
Topics: Acute Disease; Chronic Disease; Humans; Injections, Intravenous; Lidocaine; Lung Diseases, Obstructi | 1972 |
Limitations of lignocaine in control of early ventricular dysrhythmias complicating acute myocardial infarction.
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Heart Ventricles; Humans; Lidocaine; Myocardial Infarc | 1972 |
Acute myocardial infarction complications and management.
Topics: Acute Disease; Arrhythmias, Cardiac; Atropine; Digitalis Glycosides; Electric Countershock; Humans; | 1971 |
[Lignocaine in the treatment of arrhythmia in acute myocardial infarct].
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Evaluation Studies as Topic; Female; Heart Ventric | 1971 |
The use of epidural block in acute pancreatitis: a report of eight cases.
Topics: Acute Disease; Adult; Aged; Anesthesia, Spinal; Electrocardiography; Electrolytes; Female; Humans; L | 1969 |
[Therapeutic results in acute reduction of hearing].
Topics: Acute Disease; Autonomic Nerve Block; Deafness; Hearing; Hearing Disorders; Humans; Lidocaine; Nicot | 1969 |
[Ventricular fibrillation in acute myocardial infarct. Apropos of 7 cases with recovery].
Topics: Acute Disease; Aged; Electric Countershock; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial | 1969 |
Ventricular parasystole in acute myocardial infarction.
Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Digitalis Glycosides; Electrocardiography; Female; Humans | 1970 |
Some observations in the management of 300 cases of acute myocardial infarction treated in the intensive coronary care unit.
Topics: Acute Disease; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atropine; Coronary Care Units; Female; Human | 1970 |
[Acute cardiac arrhythmia].
Topics: Acute Disease; Arrhythmias, Cardiac; Digitalis Glycosides; Electric Countershock; Female; Humans; Li | 1971 |
Immediate treatment of myocardial infarction.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Atropine; Electrocardiography; Hospitalization; Hu | 1971 |
[Personal experiences with prolonged administration of drip infusions of xylocaine in the early period of myocardial infarct].
Topics: Acute Disease; Arrhythmias, Cardiac; Female; Humans; Infusions, Parenteral; Lidocaine; Male; Myocard | 1971 |
Primary ventricular fibrillation complicating acute myocardial infarction.
Topics: Acute Disease; Adult; Age Factors; Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; | 1971 |
[Lidocaine in the acute phase of myocardial infarct].
Topics: Acute Disease; Humans; Lidocaine; Myocardial Infarction | 1971 |
Atrial pacing to control heart rate and rhythm in acute cardiac conditions.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Volume; Bradycardia; Cardiac Catheterization | 1971 |
Pre-hospital phase of an acute coronary attack. Treatment with combination of intravenous and intramuscular lidocaine.
Topics: Acute Disease; Coronary Disease; Hospitalization; Humans; Injections, Intramuscular; Injections, Int | 1971 |
[Adverse effects of lidocaine as an anti-arrhythmic drug].
Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Lidocaine; Male; Mid | 1971 |
Intractable hiccuping in acute myocardial infarction.
Topics: Acute Disease; Aged; Chlorpromazine; Hiccup; Humans; Injections, Intramuscular; Lidocaine; Male; Myo | 1971 |
[Lidocaine as an anti-arrhythmia agent. Experiences with 68 patients].
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Injections, I | 1969 |
The long-term prognosis for patients resuscitated after cardiac arrest. A follow-up study.
Topics: Acute Disease; Adult; Aged; Coronary Disease; Follow-Up Studies; Heart Arrest; Heart Massage; Humans | 1969 |