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lidocaine and Acute Disease

lidocaine has been researched along with Acute Disease in 243 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"This randomized study suggests that topical 1% lidocaine ear drops with paracetamol or ibuprofen seems to provide effective and rapid relief for children presenting with ear pain attributed to AOM."9.51The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media. ( Alabaz, D; Albayrak, E; Bedir, T; Bozdemir, ŞE; Büyükcam, A; Çelebi, S; Çiftçi, E; İlarslan, EÇ; Kara, A; Kara, M; Kara, SS; Kara, TT; Karakaşlılar, S; Karbuz, A; Kaya, C; Öz, FN; Özdemir, H; Sali, E; Somer, A; Sönmez, G; Sütçü, M; Tezer, H, 2022)
"An echinacea/sage preparation is as efficacious and well tolerated as a chlorhexidine/lidocaine spray in the treatment of acute sore throats."9.14Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial. ( Berger, D; Klein, P; Schapowal, A; Suter, A, 2009)
"Topical lidocaine has been recently marketed as a new treatment for post-herpetic neuralgia."9.10Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster. ( Benowitz, NL; Campbell, BJ; Davies, PS; Jacob, P; Rowbotham, M, 2002)
"Our study clearly demonstrates that the use of topical nifedipine, which at present is for treatment of cardiovascular disorders, is a reliable new option in the conservative treatment of thrombosed external hemorrhoids."9.09Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine. ( Antropoli, C; Antropoli, M; De Stefano, G; Molino, D; Perrotti, P, 2001)
"Topical application of nitroglycerine represents a new, easily handled, and effective alternative in the treatment of anal fissures."9.08Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy? ( Bacher, H; Cerwenka, H; El-Shabrawi, A; Mischinger, HJ; Pfeifer, J; Schweiger, W; Werkgartner, G, 1997)
"Fifty-five patients with shoulder pain due to rotator cuff tendinitis of less than 12 weeks' duration were randomized to receive either 40 mg methylprednisolone and lignocaine or lignocaine alone."9.07A double-blind trial comparing subacromial methylprednisolone and lignocaine in acute rotator cuff tendinitis. ( Hazleman, BL; King, RH; Vecchio, PC, 1993)
"The treatment of dyspepsia in the emergency department often consists of antacid in combination with viscous lidocaine, even though the specific etiology of the pain is frequently unknown."9.06The emergency department treatment of dyspepsia with antacids and oral lidocaine. ( Watson, WA; Welling, LR, 1990)
"In this double-blind parallel study, 99 patients with acute ventricular tachyarrhythmias after open-heart surgery were given either tocainide (50 patients) or lidocaine (49 patients) intravenously as 2 bolus injections 15 minutes apart, plus a fixed-rate infusion that started at the first bolus."9.05Efficacy and safety of intravenous tocainide compared with intravenous lidocaine for acute ventricular arrhythmias immediately after cardiac surgery. ( Harley, S; Johnson, J; MacVaugh, H; Morganroth, J; Panidis, IP; Smith, E, 1984)
"Twenty-six patients with clinically significant ventricular arrhythmias were randomly assigned to treatment with either intravenous disopyramide or lidocaine; crossover to the other agent was permitted in nine cases of primary drug failure."9.04Suppression of ventricular arrhythmias with intravenous disopyramide and lidocaine: efficacy comparison in a randomized trial. ( Fozzard, HA; Rawling, DA; Sbarbaro, JA, 1979)
"Patients with suspected or proven acute myocardial infarction complicated by ventricular arrhythmias not corrected by lidocaine therapy (bolus dose 100 mg followed by infusion 2 mg/min) were treated either with an increased dose of lidocaine (bolus dose 50 mg followed by infusion 3 mg/min) or with 600 mg N,N-bis dimethylammonium chloride (QX-572, Astra, Sweden) as an i."9.04Lidocaine and the quarternary ammonium compound QX-572 in acute myocardial infarction. A comparative study. ( Bergdahl, B; Karlsson, E; Magnusson, JO; Sonnhag, C, 1978)
"In acute myocardial infarction, lidocaine is considered the drug of choice for the treatment of malignant ventricular arrhythmias."8.78Lidocaine in the early phase of acute myocardial infarction: the controversy over prophylactic or selective use. ( Just, H; Kasper, W; Zehender, M, 1990)
"Intra-arterial lidocaine infusion into the celiac trunk decreases pancreatitis severity."7.96Efficacy of intra-arterial lidocaine infusion in the treatment of cerulein-induced acute pancreatitis. ( Antkowiak, R; Antkowiak, Ł; Arent, Z; Domosławski, P; Grzegorczyn, S; Kabała, N; Nalik-Iwaniak, K; Stęplewska, K; Warmusz-Reichman, E, 2020)
"A 37-year-old man with known intravenous drug abuse presented in the surgical ambulatory care unit with acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets into the right femoral artery."7.77Successful thrombolysis and spasmolysis of acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets. ( Bellemann, N; Boeckler, D; Hyhlik-Duerr, A; Kauczor, HU; Radeleff, B; Sommer, CM; Stampfl, U; Weber, MA, 2011)
"This case report describes an uncommon complication (blindness) occurring after an inadvertent overdosage of a frequently used local anesthetic (lidocaine) during a regional anesthetic procedure."7.71Temporary bilateral blindness after acute lidocaine toxicity. ( Sawyer, RJ; von Schroeder, H, 2002)
"In a rat model of intracranial balloon inflation, intrathecal lidocaine prevented cardiovascular collapse and neurogenic pulmonary edema."7.71Intrathecal lidocaine prevents cardiovascular collapse and neurogenic pulmonary edema in a rat model of acute intracranial hypertension. ( Ford, S; Hall, SR; Hong, M; Milne, B; Wang, L, 2002)
"Despite continuing controversies regarding its antiarrhythmic and antifibrillatory efficacy lidocaine is frequently used for the treatment of ventricular arrhythmias occurring in the early phase of acute myocardial infarction (MI)."7.69Facilitation of reentry by lidocaine in canine myocardial infarction. ( Fazekas, T; Lazzara, R; Mabo, P; Patterson, E; Scherlag, BJ, 1994)
"We evaluate the analgesic efficacy and safety of 9% (wt/vol) lidocaine (base) in petrolatum/paraffin ointment in patients with acute herpes zoster."7.69Treatment of the cutaneous pain of acute herpes zoster with 9% lidocaine (base) in petrolatum/paraffin ointment. ( Cork, RC; Dunston, A; Eyrich, J; Heitler, D; Johnson, W; Lopez-Anaya, A; Naraghi, M; Ragan, A; Riopelle, AJ; Riopelle, J, 1994)
"The effects of acute changes in plasma magnesium concentration on the threshold for lidocaine-induced seizures were evaluated in mechanically ventilated rats receiving 70% nitrous oxide and 30% oxygen."7.68Effects of acute hypermagnesemia on the threshold for lidocaine-induced seizures in the rat. ( Choi, WW; Monahan, DJ; Todd, MM; Warner, DS, 1991)
"To evaluate the pharmacodynamics of intravenous lidocaine in patients with acute-onset and chronic ventricular arrhythmias."7.68Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias. ( Destache, CJ; Hilleman, DE; Hunter, CB; Mohiuddin, SM; Mooss, AN; Sketch, MH, 1992)
" The new strategy has been illustrated in a case-control investigation of whether lidocaine prophylaxis prevents death in patients with acute myocardial infarction."7.66Improved observational method for studying therapeutic efficacy. Suggestive evidence that lidocaine prophylaxis prevents death in acute myocardial infarction. ( Feinstein, AR; Horwitz, RI, 1981)
"An acute pharyngitis is characterised by mild to severe sore throat mostly accompanied by inflammation, throat pain, pain on swallowing, and burning."6.73Lidocaine 8 mg sore throat lozenges in the treatment of acute pharyngitis. A new therapeutic option investigated in comparison to placebo treatment. ( Blume, HH; Canenbley, R; Donath, F; Helm, I; Nowak, H; Röttger-Luer, P; Schug, BS; Stauss-Grabo, M; Tran, CT; Wonnemann, M, 2007)
"This randomized study suggests that topical 1% lidocaine ear drops with paracetamol or ibuprofen seems to provide effective and rapid relief for children presenting with ear pain attributed to AOM."5.51The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media. ( Alabaz, D; Albayrak, E; Bedir, T; Bozdemir, ŞE; Büyükcam, A; Çelebi, S; Çiftçi, E; İlarslan, EÇ; Kara, A; Kara, M; Kara, SS; Kara, TT; Karakaşlılar, S; Karbuz, A; Kaya, C; Öz, FN; Özdemir, H; Sali, E; Somer, A; Sönmez, G; Sütçü, M; Tezer, H, 2022)
" High-dose topiramate combined with high-dose lidocaine infusion or high-dose phenobarbital in the acute stage might be an effective treatment option for children with AERRPS."5.35Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures. ( Hsia, SH; Lin, JJ; Lin, KL; Wang, HS; Wu, CT, 2009)
"Pretreatment with lidocaine also greatly attenuated the acute hypertension and the increase in intracranial pressure following air embolism."5.27Protective effect of lidocaine in acute cerebral ischemia induced by air embolism. ( Bradley, ME; Evans, DE; Kobrine, AI; LeGrys, DC, 1984)
"An echinacea/sage preparation is as efficacious and well tolerated as a chlorhexidine/lidocaine spray in the treatment of acute sore throats."5.14Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial. ( Berger, D; Klein, P; Schapowal, A; Suter, A, 2009)
"From this preliminary study, intravenous injection of lidocaine seems to be safe and effective in controlling intraocular pressure and eliminating symptoms in acute PACG."5.12Efficacy and safety of intravenous injection of lidocaine in the treatment of acute primary angle-closure glaucoma: a pilot study. ( Dong, XD; Jin, X; Qin, Q; Qu, J; Xue, A; Zhao, Y, 2007)
"Topical lidocaine has been recently marketed as a new treatment for post-herpetic neuralgia."5.10Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster. ( Benowitz, NL; Campbell, BJ; Davies, PS; Jacob, P; Rowbotham, M, 2002)
"Our study clearly demonstrates that the use of topical nifedipine, which at present is for treatment of cardiovascular disorders, is a reliable new option in the conservative treatment of thrombosed external hemorrhoids."5.09Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine. ( Antropoli, C; Antropoli, M; De Stefano, G; Molino, D; Perrotti, P, 2001)
"Topical application of nitroglycerine represents a new, easily handled, and effective alternative in the treatment of anal fissures."5.08Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy? ( Bacher, H; Cerwenka, H; El-Shabrawi, A; Mischinger, HJ; Pfeifer, J; Schweiger, W; Werkgartner, G, 1997)
"Fifty-five patients with shoulder pain due to rotator cuff tendinitis of less than 12 weeks' duration were randomized to receive either 40 mg methylprednisolone and lignocaine or lignocaine alone."5.07A double-blind trial comparing subacromial methylprednisolone and lignocaine in acute rotator cuff tendinitis. ( Hazleman, BL; King, RH; Vecchio, PC, 1993)
"The treatment of dyspepsia in the emergency department often consists of antacid in combination with viscous lidocaine, even though the specific etiology of the pain is frequently unknown."5.06The emergency department treatment of dyspepsia with antacids and oral lidocaine. ( Watson, WA; Welling, LR, 1990)
"In this double-blind parallel study, 99 patients with acute ventricular tachyarrhythmias after open-heart surgery were given either tocainide (50 patients) or lidocaine (49 patients) intravenously as 2 bolus injections 15 minutes apart, plus a fixed-rate infusion that started at the first bolus."5.05Efficacy and safety of intravenous tocainide compared with intravenous lidocaine for acute ventricular arrhythmias immediately after cardiac surgery. ( Harley, S; Johnson, J; MacVaugh, H; Morganroth, J; Panidis, IP; Smith, E, 1984)
"Twenty-six patients with clinically significant ventricular arrhythmias were randomly assigned to treatment with either intravenous disopyramide or lidocaine; crossover to the other agent was permitted in nine cases of primary drug failure."5.04Suppression of ventricular arrhythmias with intravenous disopyramide and lidocaine: efficacy comparison in a randomized trial. ( Fozzard, HA; Rawling, DA; Sbarbaro, JA, 1979)
"Patients with suspected or proven acute myocardial infarction complicated by ventricular arrhythmias not corrected by lidocaine therapy (bolus dose 100 mg followed by infusion 2 mg/min) were treated either with an increased dose of lidocaine (bolus dose 50 mg followed by infusion 3 mg/min) or with 600 mg N,N-bis dimethylammonium chloride (QX-572, Astra, Sweden) as an i."5.04Lidocaine and the quarternary ammonium compound QX-572 in acute myocardial infarction. A comparative study. ( Bergdahl, B; Karlsson, E; Magnusson, JO; Sonnhag, C, 1978)
"In acute myocardial infarction, lidocaine is considered the drug of choice for the treatment of malignant ventricular arrhythmias."4.78Lidocaine in the early phase of acute myocardial infarction: the controversy over prophylactic or selective use. ( Just, H; Kasper, W; Zehender, M, 1990)
" Early and adequate intravenous antiarrhythmic prophylaxis with lidocaine to raise the fibrillation threshold in the setting of coronary insufficiency can prevent primary ventricular fibrillation."4.75The management of acute coronary insufficiency. ( Baker, J; Greenfield, JC; Wagner, GS, 1977)
"Intra-arterial lidocaine infusion into the celiac trunk decreases pancreatitis severity."3.96Efficacy of intra-arterial lidocaine infusion in the treatment of cerulein-induced acute pancreatitis. ( Antkowiak, R; Antkowiak, Ł; Arent, Z; Domosławski, P; Grzegorczyn, S; Kabała, N; Nalik-Iwaniak, K; Stęplewska, K; Warmusz-Reichman, E, 2020)
"A 37-year-old man with known intravenous drug abuse presented in the surgical ambulatory care unit with acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets into the right femoral artery."3.77Successful thrombolysis and spasmolysis of acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets. ( Bellemann, N; Boeckler, D; Hyhlik-Duerr, A; Kauczor, HU; Radeleff, B; Sommer, CM; Stampfl, U; Weber, MA, 2011)
" Subdiaphragmatic vagotomy and abdominal perivagal lidocaine administration, or lidocaine injection into the nucleus tractus solitarius (NTS) prevented LPS hypotension."3.74Lipopolysaccharide-induced hypotension is mediated by a neural pathway involving the vagus nerve, the nucleus tractus solitarius and alpha-adrenergic receptors in the preoptic anterior hypothalamic area. ( Cutrera, RA; Feleder, C; Goktalay, G; Millington, WR; Myer, BS; Yilmaz, MS, 2008)
"In a rat model of intracranial balloon inflation, intrathecal lidocaine prevented cardiovascular collapse and neurogenic pulmonary edema."3.71Intrathecal lidocaine prevents cardiovascular collapse and neurogenic pulmonary edema in a rat model of acute intracranial hypertension. ( Ford, S; Hall, SR; Hong, M; Milne, B; Wang, L, 2002)
"This case report describes an uncommon complication (blindness) occurring after an inadvertent overdosage of a frequently used local anesthetic (lidocaine) during a regional anesthetic procedure."3.71Temporary bilateral blindness after acute lidocaine toxicity. ( Sawyer, RJ; von Schroeder, H, 2002)
"Metaanalysis of data from 20 years of randomized trials of lidocaine prophylaxis in preventing primary ventricular fibrillation (VF) in myocardial infarction used separate data for control and active-treatment groups to model the risk of VF as a function of year of publication and other study characteristics."3.69Advantages and limitations of metaanalytic regressions of clinical trials data. ( Antman, EM; Berlin, JA, 1994)
"The aim of this study was to elucidate whether the electrophysiologic properties of pilsicainide, a novel class IC drug with slow kinetic properties, could be altered in the presence of acute myocardial ischemia."3.69Ischemia enhances use-dependent sodium channel blockade by pilsicainide, a class IC antiarrhythmic agent. ( Ogawa, S; Sadanaga, T, 1994)
"We evaluate the analgesic efficacy and safety of 9% (wt/vol) lidocaine (base) in petrolatum/paraffin ointment in patients with acute herpes zoster."3.69Treatment of the cutaneous pain of acute herpes zoster with 9% lidocaine (base) in petrolatum/paraffin ointment. ( Cork, RC; Dunston, A; Eyrich, J; Heitler, D; Johnson, W; Lopez-Anaya, A; Naraghi, M; Ragan, A; Riopelle, AJ; Riopelle, J, 1994)
"Despite continuing controversies regarding its antiarrhythmic and antifibrillatory efficacy lidocaine is frequently used for the treatment of ventricular arrhythmias occurring in the early phase of acute myocardial infarction (MI)."3.69Facilitation of reentry by lidocaine in canine myocardial infarction. ( Fazekas, T; Lazzara, R; Mabo, P; Patterson, E; Scherlag, BJ, 1994)
"An equal degree of acute hypertension induced by these three different vasopressors may play a role in reducing the threshold (plasma and brain lidocaine concentrations) as well as the cumulative convulsant doses associated with lidocaine-induced convulsions."3.69Effect of vasoconstrictive agents added to lidocaine on intravenous lidocaine-induced convulsions in rats. ( Goto, H; Hirakawa, M; Yokoyama, M, 1995)
"To evaluate the pharmacodynamics of intravenous lidocaine in patients with acute-onset and chronic ventricular arrhythmias."3.68Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias. ( Destache, CJ; Hilleman, DE; Hunter, CB; Mohiuddin, SM; Mooss, AN; Sketch, MH, 1992)
"The effects of acute changes in plasma magnesium concentration on the threshold for lidocaine-induced seizures were evaluated in mechanically ventilated rats receiving 70% nitrous oxide and 30% oxygen."3.68Effects of acute hypermagnesemia on the threshold for lidocaine-induced seizures in the rat. ( Choi, WW; Monahan, DJ; Todd, MM; Warner, DS, 1991)
"Patients with acute hepatitis and patients with compensated or decompensated cirrhosis of the liver have a decreased plasma clearance of hexobarbital."3.66[Drug metabolism in patients with liver disease (author's transl)]. ( Epping, J; Fuchshofen-Röckel, M; Heusler, H; Richter, E; Zilly, W, 1980)
"Technetium-99m dimethyl acetanilide iminodiacetic acid (HIDA) cholescintigraphy was performed on 90 patients with suspected acute cholecystitis."3.66Rapid and accurate diagnosis of acute cholecystitis with 99mTc-HIDA cholescintigraphy. ( Bernstein, LH; Frank, MS; Freeman, LM; Weissmann, HS, 1979)
" The new strategy has been illustrated in a case-control investigation of whether lidocaine prophylaxis prevents death in patients with acute myocardial infarction."3.66Improved observational method for studying therapeutic efficacy. Suggestive evidence that lidocaine prophylaxis prevents death in acute myocardial infarction. ( Feinstein, AR; Horwitz, RI, 1981)
"The effect of administration of lidocaine on left ventricular performance was studied using systolic time intervals in nine normal subjects, eight patients with stable angina, and 15 patients with acute myocardial infarction."3.65Negative inotropic effect of lidocaine in patients with coronary arterial disease and normal subjects. ( Boudoulas, H; DeGreen, P; Kates, RE; Lewis, RP; Schaal, SF; Welch, TG, 1977)
"Included patients met the migraine criteria of the International Headache Society."2.84Intranasal Lidocaine in Acute Treatment of Migraine: A Randomized Controlled Trial. ( Akalın, LE; Alyeşil, C; Avcu, N; Doğan, NÖ; Pekdemir, M; Yaka, E; Yılmaz, S, 2017)
"Local methylcobalamin combined with lidocaine, optimally administered within 4-7 days of onset, may be an effective therapeutic option for acute herpetic neuralgia."2.82Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia. ( Cheng, C; Tang, WZ; Xǔ, G; Xu, J; Xu, S, 2016)
"Early repair of rotator cuff tears leads to superior results."2.75The value of clinical tests in acute full-thickness tears of the supraspinatus tendon: does a subacromial lidocaine injection help in the clinical diagnosis? A prospective study. ( Bak, K; Jørgensen, U; Krarup, AL; Nygaard, M; Pedersen, ST; Sloth, C; Sørensen, AK; Thune, C, 2010)
"An acute pharyngitis is characterised by mild to severe sore throat mostly accompanied by inflammation, throat pain, pain on swallowing, and burning."2.73Lidocaine 8 mg sore throat lozenges in the treatment of acute pharyngitis. A new therapeutic option investigated in comparison to placebo treatment. ( Blume, HH; Canenbley, R; Donath, F; Helm, I; Nowak, H; Röttger-Luer, P; Schug, BS; Stauss-Grabo, M; Tran, CT; Wonnemann, M, 2007)
"No differences were noted in postoperative pain, the total number of analgesic doses per day, the quantity of narcotic medication administered, and the length of hospital stay."2.68Preemptive analgesia in patients undergoing appendectomy. ( Alcantara, A; Hiyama, D; Ko, CY; Thompson, JE, 1997)
"Subjects scored the intensity of headache and nausea on separate visual analogue scales before the injection and at 10 and 20 min after injection."2.67Is intravenous lidocaine clinically effective in acute migraine? ( Fatovich, DM; Prentice, DA; Reutens, DC; Stewart-Wynne, EG, 1991)
"It is effective against ventricular arrhythmias, both parenterally and orally, and has been used in acute myocardial infarction, in the convalescence following myocardial infarction and in ventricular arrhythmias of different aetiology."2.65Mexiletine in clinical practice. ( Boyle, DM, 1980)
"Lidocaine should not be used to treat painful mouth lesions in children until further safety data are available."2.39Lidocaine overdose: another preventable case? ( Druckenbrod, RW; Gonzalez del Rey, J; Wason, S, 1994)
"Ventricular arrhythmias represent a common precursor of ventricular fibrillation in acute myocardial infarction in man."2.36[Prognostic significance of arrhythmias in acute myocardial infarction (author's transl)]. ( Breithardt, G; Loogen, F; Seipel, L, 1977)
" High-dose topiramate combined with high-dose lidocaine infusion or high-dose phenobarbital in the acute stage might be an effective treatment option for children with AERRPS."1.35Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures. ( Hsia, SH; Lin, JJ; Lin, KL; Wang, HS; Wu, CT, 2009)
"Biliary acute pancreatitis or postendoscopic iatrogenia acute pancreatitis (AP) are likely triggered by autonomous arc reflexes (AAR) initiated in the peri-Vaterian duodenum (PV-D)."1.32Acute pancreatitis possible initial triggering mechanism and prophylaxis. ( Binker, MG; Cosen-Binker, LI; Negri, G; Tiscornia, O, 2003)
"Because the patient developed acute renal failure and furosemide did not show diuretic effect, hemodialysis was used."1.30[Perioperative management for acute abdominal aortic obstruction in a patient with acute myocardial reinfarction associated with acute renal failure]. ( Ishiyama, T; Tsujitou, T, 1997)
" From these findings, the present Bayesian method implemented with the estimates of pharmacokinetic parameters in a Swiss patient population is useful for sufficiently accurate and precise assessment of individual dosage requirement within a few hours after starting lidocaine therapy."1.29A prospective study for validation of Bayesian prediction approach to adjust individual lidocaine dosage. ( Hirayama, H; Kosuge, K; Nakashima, M; Uematsu, T; Umemura, K, 1994)
"The predictive performance of two computer programs for lidocaine dosing were evaluated."1.28Predictive performance of Bayesian and nonlinear least-squares regression programs for lidocaine. ( Destache, CJ; Hilleman, DE; Lang, PT; Mohiuddin, SJ, 1992)
"A case is reported of acute respiratory failure occurring during upper abdominal surgery in a patient not previously known to have chronic respiratory failure."1.28[Transient acute respiratory failure and thoracic epidural anesthesia]. ( Joyau, FH; Maries, H, 1989)
"Pretreatment with lidocaine also greatly attenuated the acute hypertension and the increase in intracranial pressure following air embolism."1.27Protective effect of lidocaine in acute cerebral ischemia induced by air embolism. ( Bradley, ME; Evans, DE; Kobrine, AI; LeGrys, DC, 1984)
"A case is reported in which acute airway obstruction followed the injection of Teflon paste into a paralysed vocal cord."1.27Respiratory obstruction following vocal cord injection of Teflon paste. ( Bates, GJ; Curley, JW; Ward, ME, 1984)
" The absence of correlation between pharmacokinetic parameters of the disposition of lidocaine and indocyanine green indicates that the influence of hepatic disease on the hepatic processes that lead to the elimination of each compound is not predictable."1.26Influence of viral hepatitis on the disposition of two compounds with high hepatic clearance: lidocaine and indocyanine green. ( Blaschke, TF; Meffin, PJ; Melmon, KL; Rowland, M; Williams, RL, 1976)
"The occipital pain and headache of cervical arthritis also often respond to injection of 2 to 3 ml of long-acting anesthetic into the greater and lesser occipital nerves at the sites where they pierce the trapezius."1.26Relieving pain with nerve blocks. ( Carron, H, 1978)
" In ten of them the main pharmacokinetic parameters were determined; the average value of lidocain clearance was 0."1.26[Lidocaine pharmacokinetics and substantiation of the new method of its administration in myocardial infarct]. ( Mazur, NA; Metelitsa, VI; Piotrovskiĭ, VK; Riabokon', OS; Smirnova, EB, 1979)
"Furthermore dangerous arrhythmias are reported in 1600 cases treated with floating catheters."1.26[Arrhythmias during catheterization of patients with acute myocardial infarction (author's transl)]. ( Enenkel, W; Jobst, C; Kiss, E; Mayer, B; Nobis, H; Pollak, H; Prachar, H; Spiel, R, 1977)
" In a guarded ward for coronary diseases since 1972 all patients with a fresh myocardial infarction or suspicion of infarction were treated with a continuous intravenous lidocain drip in a dosage of 100 mg/per hour for 48 hours."1.25[Possibilities of a routine prevention of arrhythmia in the early phase of acute myocardial infarct]. ( Fiehring, H; Kulick, B; Schaedel, H; Steffen, V, 1975)
"Of particular importance are the arrhythmias observed immediately after experimentally induced acute myocardial infarction (AMI)."1.25Pharmacological modification of arrhythmias after experimentally induced acute myocardial infarction. Drugs acting on the nervous system. ( Kniffen, FJ; Lucchesi, BR, 1975)
"This arrhythmia always appeared within the first 24 hours after the beginning of the pain, and lasted usually a few hours."1.25Ventricular parasystole in acute myocardial infarction. ( McKendrick, CS; Salazar, J, 1970)
"Nine of these had ventricular arrhythmia refractory to drugs."1.25Atrial pacing to control heart rate and rhythm in acute cardiac conditions. ( Friesen, WG, 1971)

Research

Studies (243)

TimeframeStudies, this research(%)All Research%
pre-1990145 (59.67)18.7374
1990's40 (16.46)18.2507
2000's35 (14.40)29.6817
2010's21 (8.64)24.3611
2020's2 (0.82)2.80

Authors

AuthorsStudies
Kara, A1
Büyükcam, A1
Sütçü, M1
Sali, E1
Bozdemir, ŞE1
Kara, M1
İlarslan, EÇ1
Kaya, C1
Karakaşlılar, S1
Sönmez, G1
Kara, SS1
Bedir, T1
Albayrak, E1
Kara, TT1
Çelebi, S1
Öz, FN1
Karbuz, A1
Somer, A1
Alabaz, D1
Tezer, H1
Özdemir, H1
Çiftçi, E1
Chi, PW2
Hsieh, KY2
Chen, KY1
Hsu, CW2
Bai, CH2
Chen, C2
Hsu, YP2
Antkowiak, R1
Antkowiak, Ł1
Grzegorczyn, S1
Nalik-Iwaniak, K1
Kabała, N1
Arent, Z1
Warmusz-Reichman, E1
Stęplewska, K1
Domosławski, P1
Fujii, K1
Tsai, CW1
Morgan, A1
Jessop, V1
Sun, JJ1
Chu, ZJ1
Liu, WF1
Qi, SF1
Yang, YH1
Ge, PL1
Zhang, XH1
Li, WS1
Yang, C1
Zhang, YM1
Kiselev, AB1
Chaukina, VA1
Harris, R1
Thompson, TM1
Theobald, JL1
Xǔ, G2
Xu, S1
Tang, WZ1
Cheng, C1
Xu, J1
Kwak, J1
Chung, H1
Lee, S1
Kim, Y1
Cho, S1
Seo, T1
Jo, W1
Shin, J1
Avcu, N1
Doğan, NÖ1
Pekdemir, M1
Yaka, E1
Yılmaz, S1
Alyeşil, C1
Akalın, LE1
Bharti, B1
Bharti, S1
Yilmaz, MS1
Goktalay, G1
Millington, WR1
Myer, BS1
Cutrera, RA1
Feleder, C1
Boulos, PR1
Rubin, PA1
Watson, J2
Helliwell, P2
Morton, V2
Adebajo, A2
Dickson, J2
Russell, I2
Torgerson, D2
Lin, JJ1
Lin, KL1
Wang, HS1
Hsia, SH1
Wu, CT1
McKenna, C1
Bojke, L1
Manca, A1
Rosado Caracena, R1
Uña Orejón, R1
Garrido Ortega, P1
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Antoni Schoenenberger, J1
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Henderson, LA1
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Dhinakharan, SR1
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Hong, M1
Wittke, R1
Campbell, BJ1
Rowbotham, M1
Davies, PS1
Jacob, P1
Benowitz, NL1
Sawyer, RJ1
von Schroeder, H1
Boudoulas, H1
Schaal, SF1
Lewis, RP1
Welch, TG1
DeGreen, P1
Kates, RE1
Rood, JP1
Leshchinskiĭ, LA1
Lazarenko, VG1
Schley, G1
Beckmann, R1
Hengstebeck, W1
Weissmann, HS1
Frank, MS1
Bernstein, LH1
Freeman, LM1
Carron, H1
Aleksandrow, W1
Burkart, F1
Heierli, B1
Renggli, I1
Ritz, R1
Scheidegger, F1
Schweizer, W1
Zutter, W1
Baker, J1
Wagner, GS1
Greenfield, JC1
Breithardt, G1
Seipel, L1
Loogen, F1
Bergdahl, B1
Karlsson, E1
Magnusson, JO1
Sonnhag, C1
Noneman, JW1
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Oltmanns, D1
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Sclarovsky, S1
Strasberg, B1
Lahav, M1
Lewin, RF1
Agmon, J1
Piotrovskiĭ, VK1
Smirnova, EB1
Riabokon', OS1
Mazur, NA1
Metelitsa, VI1
Sbarbaro, JA1
Rawling, DA1
Fozzard, HA1
Bray, A1
Montinaro, A1
Lombardi, R1
Calabrese, G1
De Giorgi, V1
Spirito, F1
Bacca, F1
Spiel, R1
Pollak, H1
Jobst, C1
Kiss, E1
Mayer, B1
Nobis, H1
Prachar, H1
Enenkel, W1
Kinnunen, PK1
Lempinen, M1
Lie, KI2
Bernard, R3
Vainsel, H1
Dereume, G1
de Hemptinne, J1
Smets, P1
Englert, M1
Prescott, LF1
Forrest, JA1
Adjepon-Yamoah, KK1
Finlayson, ND1
Müller, G1
Chalabi, G1
Löfmark, R1
Orinius, E2
Meytes, I1
Laniado, S1
Lehman, JS1
Basch, PF1
Burton, JR1
Mathew, MT1
Armstrong, PW1
Williams, RL1
Blaschke, TF1
Meffin, PJ1
Melmon, KL1
Rowland, M1
Rajagopalan, RS1
Appu, KS1
Kader Sultan, S1
Krämer, B1
Stephan, K1
Meesmann, W1
Hussey, HH1
Stofer, AR1
Ulrich, L1
Steinsiepe, KF1
Egger, G1
Werkö, L2
Lucchesi, BR1
Kniffen, FJ1
Wirth, F1
Kenderesi, P1
Lukl, J1
Cernosek, B1
Steffen, V1
Fiehring, H1
Kulick, B1
Schaedel, H1
Klein, MD1
Singh, JB1
Kocot, SL1
Singh, BN1
Destache, CJ2
Hilleman, DE2
Mohiuddin, SJ1
Lang, PT1
Mohiuddin, SM1
Mooss, AN1
Hunter, CB1
Sketch, MH1
Currey, TA1
Dalsania, J1
Reutens, DC1
Fatovich, DM1
Stewart-Wynne, EG1
Prentice, DA1
Braunwald, E1
Choi, WW1
Warner, DS1
Monahan, DJ1
Todd, MM1
Ceylan, S2
Kalelioğlu, M1
Aktürk, G1
Aktürk, F1
Black, RJ1
Dawson, TA1
Strang, WC1
Welling, LR1
Watson, WA1
Zehender, M1
Kasper, W1
Just, H1
Koplatadze, AM1
Lytkin, IuI1
Bondarev, IuA1
Pugachev, IuN1
Kamalov, MA1
Maries, H1
Joyau, FH1
Jensen, SL1
Thomson, AH2
Murdoch, G1
Pottage, A1
Kelman, AW2
Whiting, B2
Hillis, WS2
Abrosimov, VN1
Miralles, FS1
Lopez-Soriano, F1
Puig, MM1
Perez, D1
Lopez-Rodriguez, F1
Braun, BL1
de Vane, PJ1
Grek, OR1
Sharapov, VI1
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Dahlerup, J1
Williams, RT1
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Fothergill, WT1
Ninaber, V1
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Anderson, ST1
Allen, JD1
Geddes, JS2
James, RG1
Webb, SW1
Zaidi, SA1
Shubin, H1
Weil, MH1
Vetter, NJ1
Strange, RC1
Adams, W1
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Kühn, P1
Koller, H1
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Plante, JM1
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Valentine, PA1
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Sloman, JG1
Mueller, HS1
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Religa, A1
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Szilagyi, A2
Szeplaki, Z1
Boszormenyi, E2
Barsi, B2
Maté, K2
Lewinson, H1
Renta, C1
Thys, JP2
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Baird, CL1
Randall, RE1
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Clinical Trials (17)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sphenopalatine Ganglion Blocks for Headaches in the Emergency Department[NCT04255420]Phase 484 participants (Anticipated)Interventional2020-02-21Recruiting
Multicentric Randomized Double Blind Double Dummy Placebo Controlled Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray in Comparison to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats[NCT00707902]Phase 3154 participants (Actual)Interventional2006-02-28Completed
Double-blind Randomized Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo, in the Outpatients Area.[NCT03676556]Phase 346 participants (Anticipated)Interventional2021-06-16Recruiting
Randomised, Double-blind Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo[NCT02584335]Phase 47 participants (Actual)Interventional2015-07-31Terminated (stopped due to Difficulties with the recruitment)
A Randomized Controlled Trial Comparing Quadratus Lumborum Block and Paravertebral Block for Postoperative Analgesia in Laparoscopic Hepatectomy and Open Hepatectomy[NCT03540537]180 participants (Anticipated)Interventional2018-05-09Recruiting
A Single Center, Randomized, Double-Blind Controlled Study of Topical Endoluminal Pancreatic Duct Lidocaine for Prevention of Post-ERCP Pancreatitis[NCT00953199]506 participants (Actual)Interventional2010-03-31Completed
Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery[NCT05867342]Phase 440 participants (Actual)Interventional2017-05-12Completed
Lidocaine For Neuroprotection During Cardiac Surgery[NCT00938964]550 participants (Actual)Interventional2009-07-31Completed
Clinical Outcome in Subacute Stroke Patients With Hemiplegic Shoulder Pain and Rotator Cuff Injuries After Hyaluronic Acid Injection[NCT02465853]42 participants (Actual)Interventional2015-01-31Completed
A Randomized Controlled Trial of IV Ketorolac to Prevent Post-ERCP Pancreatitis[NCT02465138]Phase 40 participants (Actual)Interventional2023-11-30Withdrawn (stopped due to Lack of Funding)
Effects of High Intra-procedural Oxygen Fraction on Post-ERCP Pancreatitis: A Randomized Clinical Trial[NCT04876768]25 participants (Actual)Interventional2021-05-18Completed
Evaluation of Analgesia With the Use of Eutectic Mixture of Local Anesthetics (Lidocaine and Prilocaine) and Oral Solution of Glucose to 25% in Preterm Neonates During Arterial Puncture and / or the Installation of Percutaneous Catheter[NCT00808054]Phase 460 participants (Actual)Interventional2008-11-30Completed
Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444]Phase 213 participants (Actual)Interventional2017-05-23Terminated (stopped due to Efficacy was not seen after interim analysis)
Transdermal Microneedle Patch To Enhance Topical Anaesthesia Before Intravenous Line Insertion for Blood Transfusion In Paediatric Thalassemia Patients[NCT05078463]Phase 220 participants (Actual)Interventional2021-09-15Completed
Intravenous Pantoprazole vs Ranitidine in Dyspepsia in Emergency Department: A Randomized Controlled Trial.[NCT01737840]Phase 466 participants (Actual)Interventional2012-10-31Completed
Randomized Controlled Trial Comparing the Efficacy of Polyethylene Glycol Alone and Polyethylene Glycol Combined With Topical Diltiazem in Treating Anal fissure in Children[NCT02419534]Phase 446 participants (Anticipated)Interventional2014-11-30Recruiting
Transcranial Direct Current Stimulation for the Treatment of Parkinson's Disease[NCT00082342]Phase 225 participants (Actual)Interventional2003-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Post ERCP Pancreatitis is the Primary Outcome.

The primary outcome of interest will be development of acute pancreatitis defined as new or worsening abdominal pain post-ERCP associated with an increase in serum amylase at least 3 times the upper limit of normal. (NCT00953199)
Timeframe: 24-48 hours post-procedure

Interventionparticipants (Number)
Lidocaine26
Normal Saline20

Serum Amylase Levels

serum amylase levels are measure by a blood draw (NCT00953199)
Timeframe: measurement is taken 2 hrs after ERCP

Interventionunits/liter (Mean)
Lidocaine130
Normal Saline128

Duration of Surgery

(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

Interventionminutes (Mean)
1:1000 Epinephrine Plus Saline72.05
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine54.23

Estimated Blood Loss During Surgery

(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

InterventionmL (Mean)
1:1000 Epinephrine Plus Saline95.25
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine91.63

Number of Days With Postoperative Bloody Nasal Discharge

Participants indicated number of days with bloody nasal discharge postoperatively using the 1-week postoperative bleeding questionnaire. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventiondays (Mean)
1:1000 Epinephrine Plus Saline2.85
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.73

Number of Extra Pledgets Used

A pledget is a small wad of absorbent material used to stop bleeding. (NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

Interventionpledgets (Mean)
1:1000 Epinephrine Plus Saline3.25
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.63

Number of Nostrils With Continuous Fresh Bleeding

Number of nostrils with excessive fresh bleeding postoperatively using the 1-week postoperative bleeding questionnaire. Continuous fresh bleeding was defined as bleeding for over 15 minutes. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventionnostrils (Count of Units)
1:1000 Epinephrine Plus Saline7
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine5

Postoperative Bloody Discharge Grading Score

Grading of postoperative bloody discharge postoperatively assessed by patient using the 1-week postoperative bleeding questionnaire. Scores range from 0 (no bleeding) to 5 (continuous heavy bleeding necessitating medical care). (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventionscore on a scale (Mean)
1:1000 Epinephrine Plus Saline2.38
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.2

Surgical Field Grading Score

The video recording of the endoscopic sinus surgery of the participant was graded by another otolaryngology specialist postoperatively and graded according to Wormald Surgical Field Grading Scale. Scores range from 0 (no bleeding) to 10 (severe bleeding with nasal cavity filling rapidly). (NCT05867342)
Timeframe: postoperatively (approximately 20 minutes to assess)

Interventionscore on a scale (Mean)
1:1000 Epinephrine Plus Saline3.54
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine3.23

Change in Center for Epidemiological Studies Depression Scale (CES-D)

"Center for Epidemiological Studies Depression Scale (CES-D). The CES-D is a 20-item self-report examination designed to measure symptoms of depression. Subjects rate the degree to which they have experienced a range of symptoms of depression, such as I had crying spells and I felt lonely. Scores range from 0 to 60, with higher scores indicating greater depressive symptoms. Scores greater than 16 are typically considered indicative of clinically significant depression." (NCT00938964)
Timeframe: baseline, 1-year

Interventionunits on a scale (Mean)
Lidocaine-1.27
Placebo-0.89

Change in Center for Epidemiological Studies Depression Scale (CES-D)

"Center for Epidemiological Studies Depression Scale (CES-D). The CES-D is a 20-item self-report examination designed to measure symptoms of depression. Subjects rate the degree to which they have experienced a range of symptoms of depression, such as I had crying spells and I felt lonely. Scores range from 0 to 60, with higher scores indicating greater depressive symptoms. Scores greater than 16 are typically considered indicative of clinically significant depression." (NCT00938964)
Timeframe: baseline, 6-weeks

Interventionunits on a scale (Mean)
Lidocaine0.57
Placebo0.16

Change in Cognitive Function From Baseline

To characterize cognitive function over time, while minimizing potential redundancy in the cognitive measures, a factor analysis was performed on the 14 cognitive test scores from baseline. We chose a five-factor solution, which represents 5 cognitive domains: structured verbal memory, unstructured verbal memory, executive function, visual memory and attention/concentration. To quantify overall cognitive function, a baseline cognitive index was first calculated as the mean of the 5 preoperative domain scores. The cognitive index score has a mean of zero, thus any positive score is above the mean, any negative score is below the mean. A continuous change score was then calculated by subtracting the baseline from the 1 year cognitive index. The resulting outcome measure is unbounded with standard deviation of 0.35. A negative change score indicating decline and a positive score indicating improvement (NCT00938964)
Timeframe: 1 year after surgery

Interventionunits on a scale (Mean)
Lidocaine0.09
Placebo0.07

Change in Cognitive Function From Baseline Characterized as Continuous Cognitive Change

To characterize cognitive function over time, while minimizing potential redundancy in the cognitive measures, a factor analysis was performed on the 14 cognitive test scores from baseline. We chose a five-factor solution, which represents 5 cognitive domains: structured verbal memory, unstructured verbal memory, executive function, visual memory and attention/concentration. To quantify overall cognitive function, a baseline cognitive index was first calculated as the mean of the 5 preoperative domain scores. The cognitive index score has a mean of zero, thus any positive score is above the mean, any negative score is below the mean. A continuous change score was then calculated by subtracting the baseline from the 6-week cognitive index. The resulting outcome measure is unbounded with standard deviation of 0.35. A negative change score indicating decline and a positive score indicating improvement. (NCT00938964)
Timeframe: Preoperative to 6 weeks after surgery

Interventionunits on a scale (Mean)
Lidocaine0.07
Placebo0.07

Change in Duke Activity Status Index (DASI)

"The DASI is a 12-item scale of functional capacity that has been found to correlate well with objective measures of maximal exercise capacity. Items reflect activities of personal care, ambulation, household tasks, sexual function, and recreational activities. Activities done with no difficulty receive scores, which are weighted and summed, for a quantitative measure of functional status. Scores range from 0 to 60; a higher-weighted score indicates better function." (NCT00938964)
Timeframe: baseline, 1-year

Interventionunits on a scale (Mean)
Lidocaine6.3
Placebo6.96

Change in Duke Activity Status Index (DASI)

"The DASI is a 12-item scale of functional capacity that has been found to correlate well with objective measures of maximal exercise capacity. Items reflect activities of personal care, ambulation, household tasks, sexual function, and recreational activities. Activities done with no difficulty receive scores, which are weighted and summed, for a quantitative measure of functional status. Scores range from 0 to 60; a higher-weighted score indicates better function." (NCT00938964)
Timeframe: baseline, 6-weeks

Interventionunits on a scale (Mean)
Lidocaine-10.98
Placebo-11.67

Change in Neurological Function, as Measured by the National Institutes of Health Stroke Scale (NIHSS)

The National Institutes of Health Stroke Scale (NIHSS) is a 15-item neurologic examination stroke scale used to evaluate the effect of acute cerebral infarction on the levels of consciousness, language, neglect, visual-field loss, extraocular movement, motor strength, ataxia, dysarthria, and sensory loss. A trained observer rates the patent's ability to answer questions and perform activities. Ratings for each item are scored with 3 to 5 grades with 0 as normal, and there is an allowance for untestable items. The range of scores is from 0 (normal) to 42 (profound effect of stroke on patient). (NCT00938964)
Timeframe: baseline, 1-year

Interventionunits on a scale (Mean)
Lidocaine0.05
Placebo0.07

Change in Neurological Function, as Measured by the National Institutes of Health Stroke Scale (NIHSS)

The National Institutes of Health Stroke Scale (NIHSS) is a 15-item neurologic examination stroke scale used to evaluate the effect of acute cerebral infarction on the levels of consciousness, language, neglect, visual-field loss, extraocular movement, motor strength, ataxia, dysarthria, and sensory loss. A trained observer rates the patent's ability to answer questions and perform activities. Ratings for each item are scored with 3 to 5 grades with 0 as normal, and there is an allowance for untestable items. The range of scores is from 0 (normal) to 42 (profound effect of stroke on patient). (NCT00938964)
Timeframe: baseline, 6-weeks

Interventionunits on a scale (Mean)
Lidocaine0.05
Placebo0.04

Change in Neurological Function, as Measured by the Western Perioperative Neurologic Scale (WPNS)

The Western perioperative neurologic scale was designed to detect neurologic deficits after cardiac surgery. It includes 14 items classified into eight domains (mentation, speech, cranial nerve function, motor weakness, sensation and cerebellum, reflexes, and gait). Each item is scored from 0 (severe deficit) to3 (normal), and a maximum score of 42 indicates normal neurological function. (NCT00938964)
Timeframe: baseline, 1-year

Interventionunits on a scale (Mean)
Lidocaine0.02
Placebo-0.02

Change in Neurological Function, as Measured by the Western Perioperative Neurologic Scale (WPNS)

The Western perioperative neurologic scale was designed to detect neurologic deficits after cardiac surgery. It includes 14 items classified into eight domains (mentation, speech, cranial nerve function, motor weakness, sensation and cerebellum, reflexes, and gait). Each item is scored from 0 (severe deficit) to3 (normal), and a maximum score of 42 indicates normal neurological function. (NCT00938964)
Timeframe: baseline, 6-weeks

Interventionunits on a scale (Mean)
Lidocaine0.04
Placebo-0.01

Change in Perceived Social Support

"Perceived Social Support Scale: Twelve items indicate how strongly subjects agree that there is a special person who is around when I am in need and my family really tries to help me. Choices range from very strongly disagree to very strongly agree. Items are summed for a range of 12 to 84, with a high score meaning more social support." (NCT00938964)
Timeframe: baseline, 1-year

Interventionunits on a scale (Mean)
Lidocaine0.71
Placebo-1.16

Change in Perceived Social Support

"Perceived Social Support Scale: Twelve items indicate how strongly subjects agree that there is a special person who is around when I am in need and my family really tries to help me. Choices range from very strongly disagree to very strongly agree. Items are summed for a range of 12 to 84, with a high score meaning more social support." (NCT00938964)
Timeframe: baseline, 6-weeks

Interventionunits on a scale (Mean)
Lidocaine1.23
Placebo-0.49

Change in Social Activity

"Social Activity: This measure consisted of eight items that indicate the degree of social interaction. Sample items are How often do you talk on the telephone with friends and relatives? and How often do you attend meetings of social groups, clubs, or civic organizations? Scores range from 8 to 32. A lower score indicates more social activity." (NCT00938964)
Timeframe: baseline, 1-year

Interventionunits on a scale (Mean)
Lidocaine-0.20
Placebo0.03

Change in Social Activity

"Social Activity: This measure consisted of eight items that indicate the degree of social interaction. Sample items are How often do you talk on the telephone with friends and relatives? and How often do you attend meetings of social groups, clubs, or civic organizations? Scores range from 8 to 32. A lower score indicates more social activity." (NCT00938964)
Timeframe: baseline, 6-weeks

Interventionunits on a scale (Mean)
Lidocaine0.95
Placebo1.59

Change in Spielberger State Anxiety Inventory (STAI)

"Spielberger State Anxiety Inventory (STAI): The STAI consists of two 20-item scales that measure anxiety. Representative items include statements such as I feel nervous and I feel worried. These items are rated on a 4-point scale, based on how well they describe the patient's current or typical mood, from not at all to very much so. Scores range from 20 to 80, with higher scores indicating greater anxiety." (NCT00938964)
Timeframe: baseline, 1-year

Interventionunits on a scale (Mean)
Lidocaine-6.70
Placebo-6.39

Change in Spielberger State Anxiety Inventory (STAI)

"Spielberger State Anxiety Inventory (STAI): The STAI consists of two 20-item scales that measure anxiety. Representative items include statements such as I feel nervous and I feel worried. These items are rated on a 4-point scale, based on how well they describe the patient's current or typical mood, from not at all to very much so. Scores range from 20 to 80, with higher scores indicating greater anxiety." (NCT00938964)
Timeframe: baseline, 6-weeks

Interventionunits on a scale (Mean)
Lidocaine-7.12
Placebo-6.31

Change in Symptom Limitations

Symptom limitations: Patients were given a list of eight symptoms and asked to rate the degree to which the symptom limited daily activities. The symptoms were angina, shortness of breath, arthritis, back trouble, leg pains, headaches, fatigue, and other. Scores range from 8 to 32, with higher scores indicating greater limitations. (NCT00938964)
Timeframe: baseline, 1-year

Interventionunits on a scale (Mean)
Lidocaine-1.39
Placebo-1.48

Change in Symptom Limitations

Symptom limitations: Patients were given a list of eight symptoms and asked to rate the degree to which the symptom limited daily activities. The symptoms were angina, shortness of breath, arthritis, back trouble, leg pains, headaches, fatigue, and other. Scores range from 8 to 32, with higher scores indicating greater limitations. (NCT00938964)
Timeframe: baseline, 6-weeks

Interventionunits on a scale (Mean)
Lidocaine-0.67
Placebo-0.8

Change in the Cognitive Difficulties Scale

"Cognitive Difficulties Scale: a 39-item scale, is a self-report assessment of perceived problems in long- and short-term memory, concentration, attention, and psycho-motor coordination. Sample items are I forget errands I planned to do and I fail to recognize people I know. Scores range from 39 to 164, with higher scores indicating greater cognitive difficulty." (NCT00938964)
Timeframe: baseline, 1-year

Interventionunits on a scale (Mean)
Lidocaine-0.46
Placebo-1.02

Change in the Cognitive Difficulties Scale

"Cognitive Difficulties Scale: a 39-item scale, is a self-report assessment of perceived problems in long- and short-term memory, concentration, attention, and psycho-motor coordination. Sample items are I forget errands I planned to do and I fail to recognize people I know. Scores range from 39 to 164, with higher scores indicating greater cognitive difficulty." (NCT00938964)
Timeframe: baseline, 6-weeks

Interventionunits on a scale (Mean)
Lidocaine-3
Placebo-3.21

Change in the Duke Older Americans Resources and Services Procedures- Instrumental Activities of Daily Living (OARS-IADL)

"Duke Older Americans Resources and Services Procedures- Instrumental Activities of Daily Living (OARS-IADL): This measure contains six items that assess the ability to perform important tasks for daily living (e.g., Could you prepare your own meals? Could you drive a car?). Scores range from 6 to 24. Higher scores indicate increasing difficulty in engaging in daily activities." (NCT00938964)
Timeframe: baseline, 1-year

Interventionunits on a scale (Mean)
Lidocaine-0.15
Placebo-0.31

Change in the Duke Older Americans Resources and Services Procedures- Instrumental Activities of Daily Living (OARS-IADL)

"Duke Older Americans Resources and Services Procedures- Instrumental Activities of Daily Living (OARS-IADL): This measure contains six items that assess the ability to perform important tasks for daily living (e.g., Could you prepare your own meals? Could you drive a car?). Scores range from 6 to 24. Higher scores indicate increasing difficulty in engaging in daily activities." (NCT00938964)
Timeframe: baseline, 6-weeks

Interventionunits on a scale (Mean)
Lidocaine2.46
Placebo2.1

Count of Participants With a Decline of Greater Than or Equal to One Standard Deviation in One or More of Five Cognitive Domain Scores Reported as a Dichotomous Post-operative Cognitive Deficit (POCD) Outcome

To characterize cognitive function over time, while minimizing potential redundancy in the cognitive measures, a factor analysis was performed on the 14 cognitive test scores from baseline. We chose a five-factor solution, which represents 5 cognitive domains: structured verbal memory, unstructured verbal memory, executive function, visual memory and attention/concentration. Each domain score is normally distributed with a mean of zero. A change score was calculated for each domain by subtracting the baseline from the 6-week score. A dichotomous outcome variable of post-operative cognitive deficit was defined as a decline of ≥1 standard deviation in 1 or more of the 5 domains. (NCT00938964)
Timeframe: Preoperative to 6 weeks after surgery

InterventionParticipants (Count of Participants)
Lidocaine87
Placebo83

Change in Study 36-Item Short Form Health Survey (SF-36)

The Medical Outcomes Study 36-Item Short Form Health Survey (SF-36): The SF-36 was designed to measure general health status. Two scales were used: Work Activities (four items) and General Health (one item). For the work activities scale, the reported score was the sum of four questions, each with values ranging from 1 to 4, the total score could range from 4 to 16. A higher score on Work Activities indicates more health-related problems For the general health question, the patients ranked their health from Excellent (1) to poor (5), the scale ranged from 1 to 5 with 1 being best health and 5 being worst. A high score in General Health indicates poorer health state. (NCT00938964)
Timeframe: baseline, 1-year

,
Interventionunits on a scale (Mean)
1 year Change Work Activities1 year Change General health perception
Lidocaine-1.37-0.28
Placebo-1.42-0.43

Change in Study 36-Item Short Form Health Survey (SF-36)

The Medical Outcomes Study 36-Item Short Form Health Survey (SF-36): The SF-36 was designed to measure general health status. Two scales were used: Work Activities (four items) and General Health (one item). For the work activities scale, the reported score was the sum of four questions, each with values ranging from 1 to 4, the total score could range from 4 to 16. A higher score on Work Activities indicates more health-related problems For the general health question, the patients ranked their health from Excellent (1) to poor (5), the scale ranged from 1 to 5 with 1 being best health and 5 being worst. A high score in General Health indicates poorer health state. (NCT00938964)
Timeframe: baseline, 6-weeks

,
Interventionunits on a scale (Mean)
6-Week Change Work activities6-Week Change General health perception
Lidocaine2.71-0.004
Placebo3-0.03

Transcerebral Activation Gradient of Platelet-neutrophil Conjugates

Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removalime points and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal

,
InterventionMean linear fluorescence intensity-MLFI (Mean)
BaselineCross-clamp removalEnd of Bypass6 hours post cross-clamp removal
Lidocaine-0.150.02-0.73-0.10
Placebo-0.43-0.73-0.400.19

Transcerebral Activation Gradients of Monocytes

Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removalime points and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal

,
InterventionMean linear fluorescence intensity-MLFI (Mean)
BaselineCross-clamp removalEnd of Bypass6 hours post cross-clamp removal
Lidocaine-4.22-2.46-0.341.21
Placebo-0.041.832.640.54

Transcerebral Activation Gradients of Neutrophils

Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removal and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal

,
InterventionMean linear fluorescence intensity-MLFI (Mean)
BaselineCross-clamp removalEnd of Bypass6 hours post cross-clamp removal
Lidocaine-2.020.560.581.04
Placebo-0.080.171.19-0.68

Transcerebral Activation Gradients of Platelets

Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removalime points and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal

,
InterventionMean linear fluorescence intensity-MLFI (Mean)
BaselineCross-clamp removalEnd of Bypass6 hours post cross-clamp removal
Lidocaine-0.030.030.330.37
Placebo0.350.430.050.27

Peak Itch Intensity Between the Vehicle and Active Treatments (Individual and KeAmLi-combo).

"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes

InterventionIntensity score (Mean)
Topical KeAmLi Combo62.7
Topical Ketamine63.1
Topical Amitriptyline69.2
Topical Lidocaine65.8
Topical Vehicle61.9

Mechanical Thresholds (Mechanical Detection and Pain).

Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes

,,,,
InterventionmN (Mean)
Mechanical Detection ThresholdMechanical Pain Threshold
Topical Amitriptyline3.573423965152.4768146
Topical KeAmLi Combo3.519376956152.3293608
Topical Ketamine3.464204768135.9
Topical Lidocaine3.546037659126.9
Topical Vehicle3.525692637148.7138273

Thermal Threshold Detection (Warmth and Heat Pain)

Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes

,,,,
InterventionDegrees celsius (Mean)
Warm Detection ThresholdHeat Pain Threshold
Topical Amitriptyline33.940.0
Topical KeAmLi Combo33.639.8
Topical Ketamine34.040.0
Topical Lidocaine33.739.4
Topical Vehicle33.839.7

Need for Additional Drug

The investigators are measuring the need for additional drug at the end of 60 minutes. (NCT01737840)
Timeframe: 60 th minute

Interventionparticipants (Number)
Pantoprazole13
Ranitidine8

Visual Analogue Scale Score

The investigators are measuring the change of pain from the baseline to the 30th and 60th minutes by visual anologue scale (VAS). Visual Analogue Scale measurement is between 0 (no pain) and 100 (worst pain). A decrease of 13 or 16 mm in VAS score is accepted as a minimum clinically significant change in pain. (NCT01737840)
Timeframe: 30th and 60th minutes

,
InterventionVisual Analogue Scale (Mean)
VAS score changes at 60 minutesVAS scores changes at 30 minutes
Pantoprazole39.627.6
Ranitidine42.328.3

Bradykinesia Measure Before and After Real and Sham tDCS.

Bradykinesia refers to the slowness in executing a movement. Bradykinesia was assessed by measuring the time in seconds it takes to do the following sequence, 10 times: 1) hand closing and opening while squeezing a ball 2) elbow flexion 3) hand closing and opening, and 4) elbow extension. Subjects were allowed to practice these hand and arm movements until performance appeared not to get faster, and then were abstained from further practice to minimize learning effects. The time it takes subjects to execute the entire sequence 10 times with either the left or right arm/hand was measured. Means are reported for each group. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, 3 months post tDCS

,,,
Interventionseconds (Mean)
Baseline1 day post tDCS1 month post tDCS3 months post tDCS
Real tDCS While Off Medication14.58.99.49.7
Real tDCS While on Medication12.38.59.19.0
Sham tDCS While Off Medication14.411.111.711.6
Sham tDCS While on Medication12.310.510.510.4

Gait Speed Before and After Real and Sham tDCS.

Gait speed was measured by the time it took the subject to walk 10m. Subjects were instructed to walk at a fast pace without taking the risk of falling, wearing the same shoes and using assistive devices consistently if needed. Gait speed was measured at baseline and post-tDCS. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, 3 months post-tDCS

,,,
InterventionSeconds (Mean)
BaselineOne day post tDCSOne month post tDCSThree month post tDCS
Real tDCS While Off Medication9.77.57.69.0
Real tDCS While on Medication8.77.27.07.2
Sham tDCS While Off Medication9.59.810.99.7
Sham tDCS While on Medication8.67.68.78.8

UPDRS Motor Scores Before and After Real tDCS Course and After Sham tDCS Course.

The Motor Unified Parkinson's Disease Rating Scale (UPDRS) includes only the motor assessment of the UPDRS (Part III) and examines speech, facial expression, tremor at rest, action tremor, rigidity, finger taps, hand movements, hand pronation and supination, leg agility, arising from chair, posture, gait, postural stability and body bradykinesia. The scores range from 0 (no motor impairment) to 108 (severe motor impairment). The Motor UPDRS was administred at baseline and at 1 day post, 1 month post, and 3 months post tDCS or sham. Subjects were assessed on medication and off medication. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, and 3 months post real and sham tDCS

,,,
Interventionunits on a scale (Mean)
Baseline1 day post tDCS1 month post tDCS3 months post tDCS
Real tDCS While Off Medication34.031.531.434.0
Real tDCS While on Medication22.220.422.723.1
Sham tDCS While Off Medication26.529.029.027.1
Sham tDCS While on Medication17.515.618.617.6

UPDRS Total Scores Before and After Real tDCS Course and After Sham tDCS Course.

The Total Unified Parkinson's Disease Rating Scale (UPDRS) is an overall clinical rating scale that quantifies the signs and symptoms of Parkinson's disease. The total UPDRS score was obtained from subject examination, subject interviews and questionnaires. The UPDRS encompasses measurement of mentation, behavior, mood, activities of daily living and motor skills. The total UPDRS scores ranges from 0 (not affected) to 176 (most severely affected). The UPDRS was administred at baseline and at 1 day post, 1 month post, and 3 months post tDCS or sham, while on medication and off medication. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, 3 months post-tDCS

,,,
Interventionunits on a scale (Mean)
Baseline1 day post tDCS1 month post tDCS3 months post tDCS
Real tDCS While Off Medication58.454.156.160.1
Real tDCS While on Medication42.536.942.543.4
Sham tDCS While Off Medication53.650.454.452.4
Sham tDCS While on Medication39.532.036.135.5

Reviews

16 reviews available for lidocaine and Acute Disease

ArticleYear
Intranasal lidocaine for acute migraine: A meta-analysis of randomized controlled trials.
    PloS one, 2019, Volume: 14, Issue:10

    Topics: Acute Disease; Administration, Intranasal; Humans; Lidocaine; Migraine Disorders; Randomized Control

2019
A case of acute pilsicainide intoxication mimicking viral encephalitis.
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2017, Volume: 30, Issue:1

    Topics: Acute Disease; Anti-Arrhythmia Agents; Diagnosis, Differential; Electrocardiography; Encephalitis, V

2017
Intranasal lidocaine for acute migraine: A protocol for the systematic review of randomized clinical trials.
    Medicine, 2019, Volume: 98, Issue:20

    Topics: Acute Disease; Administration, Intranasal; Anesthetics, Local; Humans; Lidocaine; Migraine Disorders

2019
Best BETs from the Manchester Royal Infirmary. BET 2: should intranasal lidocaine be used in patients with acute cluster headache?
    Emergency medicine journal : EMJ, 2013, Volume: 30, Issue:9

    Topics: Acute Disease; Administration, Intranasal; Anesthetics, Local; Cluster Headache; Evidence-Based Emer

2013
Severe needle phobia in the perianesthesia setting.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2007, Volume: 22, Issue:5

    Topics: Acute Disease; Adult; Ambulatory Surgical Procedures; Desensitization, Psychologic; Epilepsies, Part

2007
Recent advances in acute pain management.
    Current problems in pediatrics, 1995, Volume: 25, Issue:3

    Topics: Acute Disease; Administration, Oral; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics;

1995
Lidocaine overdose: another preventable case?
    Pediatric emergency care, 1994, Volume: 10, Issue:6

    Topics: Acute Disease; Administration, Topical; Drug Overdose; Humans; Infant; Infant, Newborn; Lidocaine; M

1994
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
    Pediatrics, 1998, Volume: 101, Issue:2

    Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan

1998
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
    Pediatrics, 1998, Volume: 101, Issue:2

    Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan

1998
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
    Pediatrics, 1998, Volume: 101, Issue:2

    Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan

1998
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
    Pediatrics, 1998, Volume: 101, Issue:2

    Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan

1998
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
    Pediatrics, 1998, Volume: 101, Issue:2

    Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan

1998
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
    Pediatrics, 1998, Volume: 101, Issue:2

    Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan

1998
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
    Pediatrics, 1998, Volume: 101, Issue:2

    Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan

1998
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
    Pediatrics, 1998, Volume: 101, Issue:2

    Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan

1998
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
    Pediatrics, 1998, Volume: 101, Issue:2

    Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan

1998
The management of acute coronary insufficiency.
    Disease-a-month : DM, 1977, Volume: 23, Issue:8

    Topics: Acute Disease; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Arteriosclerosis; Aspartate Aminotr

1977
[Prognostic significance of arrhythmias in acute myocardial infarction (author's transl)].
    Zeitschrift fur Kardiologie, 1977, Volume: 66, Issue:6

    Topics: Acute Disease; Arrhythmias, Cardiac; Coronary Care Units; Electrocardiography; Humans; Lidocaine; My

1977
Should lidocaine be administered routinely to all patients after acute myocardial infarction?
    Circulation, 1978, Volume: 58, Issue:4

    Topics: Acute Disease; Age Factors; Arrhythmias, Cardiac; Coronary Care Units; Critical Care; Electrocardiog

1978
Lidocaine prophylaxis in acute myocardial infarction.
    Medicine, 1978, Volume: 57, Issue:6

    Topics: Acute Disease; Double-Blind Method; Heart Rate; Humans; Lidocaine; Myocardial Infarction; Risk; Time

1978
Drug metabolism in liver disease.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1975, Volume: 9

    Topics: Acetaminophen; Acute Disease; Antipyrine; Chemical and Drug Induced Liver Injury; Chronic Disease; H

1975
Lidocaine in the early phase of acute myocardial infarction: the controversy over prophylactic or selective use.
    Clinical cardiology, 1990, Volume: 13, Issue:8

    Topics: Acute Disease; Arrhythmias, Cardiac; Humans; Lidocaine; Myocardial Infarction; Time Factors; Ventric

1990
Practical considerations in the management of shock complicating acute myocardial infarction. A summary of current practice.
    The American journal of cardiology, 1970, Volume: 26, Issue:6

    Topics: Acute Disease; Arrhythmias, Cardiac; Atropine; Blood Pressure Determination; Central Venous Pressure

1970
The prophylactic use of anti-arrhythmic drugs in acute myocardial infarction.
    Singapore medical journal, 1973, Volume: 14, Issue:3

    Topics: Acute Disease; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Death, Sud

1973

Trials

51 trials available for lidocaine and Acute Disease

ArticleYear
The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media.
    International journal of pediatric otorhinolaryngology, 2022, Volume: 156

    Topics: Acetaminophen; Acute Disease; Analgesics; Anti-Bacterial Agents; Child; Child, Preschool; Earache; H

2022
Perirenal space blocking restores gastrointestinal function in patients with severe acute pancreatitis.
    World journal of gastroenterology, 2013, Dec-14, Volume: 19, Issue:46

    Topics: Abdominal Pain; Acute Disease; Adult; Anesthetics, Local; Celiac Plexus; China; Female; Gastrointest

2013
[The comparative study of the of clinical effectiveness of the Candibiotic, Otipax, and Anauran ear drops for the treatment of acute external and middle ear otitis].
    Vestnik otorinolaringologii, 2013, Issue:6

    Topics: Acute Disease; Administration, Topical; Adolescent; Adult; Aged; Aminopyrine; Anti-Bacterial Agents;

2013
Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Pain medicine (Malden, Mass.), 2016, Volume: 17, Issue:3

    Topics: Acute Disease; Aged; Anesthetics, Local; Drug Therapy, Combination; Female; Humans; Injections, Subc

2016
Intranasal Lidocaine in Acute Treatment of Migraine: A Randomized Controlled Trial.
    Annals of emergency medicine, 2017, Volume: 69, Issue:6

    Topics: Acute Disease; Administration, Intranasal; Adult; Anesthetics, Local; Antiemetics; Double-Blind Meth

2017
Shoulder acute pain in primary healthcare: is retraining effective for GP principals? SAPPHIRE--a randomized controlled trial.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:12

    Topics: Acute Disease; Adult; Aged; Anesthetics, Local; Education, Medical, Continuing; Epidemiologic Method

2008
Shoulder acute pain in primary health care: is retraining GPs effective? The SAPPHIRE randomized trial: a cost-effectiveness analysis.
    Rheumatology (Oxford, England), 2009, Volume: 48, Issue:5

    Topics: Acute Disease; Anesthetics, Local; Anti-Inflammatory Agents; Cortisone; Cost-Benefit Analysis; Drug

2009
Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial.
    European journal of medical research, 2009, Sep-01, Volume: 14, Issue:9

    Topics: Acute Disease; Administration, Intranasal; Adult; Anesthetics, Local; Anti-Infective Agents, Local;

2009
Rapid relief of acute sore throat with AMC/DCBA throat lozenges: randomised controlled trial.
    International journal of clinical practice, 2010, Volume: 64, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Analgesics; Analysis of Variance; Anti-Infective Agents; Dou

2010
The value of clinical tests in acute full-thickness tears of the supraspinatus tendon: does a subacromial lidocaine injection help in the clinical diagnosis? A prospective study.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2010, Volume: 26, Issue:6

    Topics: Acute Disease; Adult; Aged; Arthroscopy; Emergencies; Female; Humans; Lidocaine; Male; Middle Aged;

2010
Glycerol lidocaine eardrops for the treatment of acute abacterial otitis externa.
    Arzneimittel-Forschung, 2010, Volume: 60, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Anesthetics, Local; Double-Blind Method; Germany; Glycerol;

2010
Blockade of branches of the ophthalmic nerve in the management of acute attack of migraine.
    Middle East journal of anaesthesiology, 2002, Volume: 16, Issue:5

    Topics: Acute Disease; Adult; Anesthetics, Local; Epinephrine; Female; Humans; Lidocaine; Middle Aged; Migra

2002
Efficacy and safety of intravenous injection of lidocaine in the treatment of acute primary angle-closure glaucoma: a pilot study.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2007, Volume: 245, Issue:11

    Topics: Acute Disease; Aged; Anesthetics, Intravenous; Antihypertensive Agents; Blood Pressure; Drug Therapy

2007
Topical lignocaine for pain relief in acute otitis media: results of a double-blind placebo-controlled randomised trial.
    Archives of disease in childhood, 2008, Volume: 93, Issue:1

    Topics: Acute Disease; Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Dou

2008
Lidocaine 8 mg sore throat lozenges in the treatment of acute pharyngitis. A new therapeutic option investigated in comparison to placebo treatment.
    Arzneimittel-Forschung, 2007, Volume: 57, Issue:11

    Topics: Acute Disease; Administration, Oral; Adult; Anesthetics, Local; Area Under Curve; Double-Blind Metho

2007
Epinephrine/Lidocaine injection vs. saline during endoscopic sinus surgery.
    The Laryngoscope, 2008, Volume: 118, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Local; Blood Loss, Surgical

2008
Drugs and the heart. VII. Which drug for which disease?
    Lancet (London, England), 1980, May-10, Volume: 1, Issue:8176

    Topics: Acute Disease; Adrenergic beta-Antagonists; Angina Pectoris; Anti-Arrhythmia Agents; Antihypertensiv

1980
The anal dilator in the conservative management of acute anal fissures.
    The British journal of surgery, 1983, Volume: 70, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Clinical Trials as Topic; Dilatation; Female; Fissure in Ano

1983
Efficacy and safety of intravenous tocainide compared with intravenous lidocaine for acute ventricular arrhythmias immediately after cardiac surgery.
    The American journal of cardiology, 1984, Dec-01, Volume: 54, Issue:10

    Topics: Acute Disease; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Surgical Procedure

1984
Mexiletine in clinical practice.
    Acta cardiologica. Supplementum, 1980, Issue:25

    Topics: Acute Disease; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Lidoc

1980
[Hemodynamic effects of lidocaine and mexiletine in acute heart infarction].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1982, Aug-01, Volume: 37, Issue:15

    Topics: Acute Disease; Female; Hemodynamics; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial In

1982
A double-blind trial comparing subacromial methylprednisolone and lignocaine in acute rotator cuff tendinitis.
    British journal of rheumatology, 1993, Volume: 32, Issue:8

    Topics: Acute Disease; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Huma

1993
Comparison of intra-articular lignocaine and a suprascapular nerve block for acute anterior shoulder dislocation.
    Injury, 1997, Volume: 28, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Fe

1997
Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy?
    Diseases of the colon and rectum, 1997, Volume: 40, Issue:7

    Topics: Acute Disease; Administration, Rectal; Administration, Topical; Adult; Anal Canal; Anesthetics, Loca

1997
Preemptive analgesia in patients undergoing appendectomy.
    Archives of surgery (Chicago, Ill. : 1960), 1997, Volume: 132, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Analgesia; Anesthetics, Local; Appendicitis; Bupivacaine; Double-B

1997
Treatment of acute supraspinatus tendinitis: physiotherapy or steroid injection?
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 1997, Volume: 4, Issue:3

    Topics: Acute Disease; Adult; Anesthetics, Local; Anti-Inflammatory Agents; Humans; Lidocaine; Methylprednis

1997
Intra-articular lignocaine versus Entonox for reduction of acute anterior shoulder dislocation.
    Injury, 1999, Volume: 30, Issue:6

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Local; Female;

1999
Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:3

    Topics: Acute Disease; Administration, Topical; Adult; Female; Hemorrhoids; Humans; Lidocaine; Male; Middle

2001
Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster.
    Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:5

    Topics: Acute Disease; Administration, Cutaneous; Administration, Topical; Adult; Aged; Aged, 80 and over; A

2002
Anti-dysrhythmic treatment in acute myocardial infarction.
    Lancet (London, England), 1979, Jan-27, Volume: 1, Issue:8109

    Topics: Acute Disease; Administration, Oral; Atenolol; Clinical Trials as Topic; Disopyramide; Double-Blind

1979
Lidocaine and the quarternary ammonium compound QX-572 in acute myocardial infarction. A comparative study.
    Acta medica Scandinavica, 1978, Volume: 204, Issue:4

    Topics: Acute Disease; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic;

1978
Lidocaine prophylaxis in acute myocardial infarction.
    Medicine, 1978, Volume: 57, Issue:6

    Topics: Acute Disease; Double-Blind Method; Heart Rate; Humans; Lidocaine; Myocardial Infarction; Risk; Time

1978
Suppression of ventricular arrhythmias with intravenous disopyramide and lidocaine: efficacy comparison in a randomized trial.
    The American journal of cardiology, 1979, Volume: 44, Issue:3

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Humans; Injections

1979
[Treatment of acute rheumatic diseases with Probaphen in private medicine].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1976, Oct-10, Volume: 52, Issue:28

    Topics: Acetaminophen; Acute Disease; Aminopyrine; Clinical Trials as Topic; Dipyrone; Drug Combinations; Dr

1976
Editorial: Lidocaine: prophylactic value in myocardial infarction.
    JAMA, 1975, Feb-10, Volume: 231, Issue:6

    Topics: Acute Disease; Adult; Clinical Trials as Topic; Female; Humans; Injections, Intramuscular; Injection

1975
A controlled trial of intramuscular lidocaine in the prevention of premature ventricular contractions associated with acute myocardial infarction.
    American heart journal, 1976, Volume: 91, Issue:4

    Topics: Acute Disease; Arrhythmias, Cardiac; Blood Pressure; Female; Heart Ventricles; Humans; Injections, I

1976
Is intravenous lidocaine clinically effective in acute migraine?
    Cephalalgia : an international journal of headache, 1991, Volume: 11, Issue:6

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male;

1991
The emergency department treatment of dyspepsia with antacids and oral lidocaine.
    Annals of emergency medicine, 1990, Volume: 19, Issue:7

    Topics: Acute Disease; Aluminum Hydroxide; Antacids; Drug Combinations; Drug Therapy, Combination; Dyspepsia

1990
Treatment of first episodes of acute anal fissure: prospective randomised study of lignocaine ointment versus hydrocortisone ointment or warm sitz baths plus bran.
    British medical journal (Clinical research ed.), 1986, May-03, Volume: 292, Issue:6529

    Topics: Acute Disease; Adult; Baths; Clinical Trials as Topic; Dietary Fiber; Female; Fissure in Ano; Humans

1986
Postoperative analgesia induced by subarachnoid lidocaine plus calcitonin.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:7

    Topics: Acute Disease; Analgesia; Calcitonin; Clinical Trials as Topic; Double-Blind Method; Female; Humans;

1987
Lignocaine given prophylactically to patients with acute myocardial infarction.
    Lancet (London, England), 1971, Mar-27, Volume: 1, Issue:7700

    Topics: Acute Disease; Arrhythmias, Cardiac; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans

1971
[Clinical experiments with a new derivative of 6-aminopenicillanic acid: hetacillin potassium].
    Minerva medica, 1972, Nov-17, Volume: 63, Issue:82

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Ampicillin; Anti-Bacterial Agents; Bacterial Infec

1972
[Lidocaine in ventricular tachycardia caused by acute myocardial infarct].
    Minerva cardioangiologica, 1974, Volume: 22, Issue:2

    Topics: Acute Disease; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Heart Ventricles; Humans; Li

1974
Prophylactic lignocaine in hospitalized patients with acute myocardial infarction.
    The Medical journal of Australia, 1973, Aug-11, Volume: 2, Issue:1

    Topics: Acute Disease; Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Lidocaine; Myocardial Infarct

1973
A double-blind trial of lidocaine in acute myocardial infarction.
    The Medical journal of Australia, 1973, Aug-11, Volume: 2, Issue:1

    Topics: Acute Disease; Age Factors; Arrhythmias, Cardiac; Clinical Trials as Topic; Female; Humans; Lidocain

1973
Propranolol in the treatment of acute myocardial infarction. Effect on myocardial oxygenation and hemodynamics.
    Circulation, 1974, Volume: 49, Issue:6

    Topics: Acute Disease; Adult; Aged; Blood Pressure; Cardiac Catheterization; Cardiac Output; Clinical Trials

1974
Anti-ischemic effect of lidocain in the acute state of myocardial infarction.
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1973, Volume: 14, Issue:5

    Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Injections, I

1973
Antiarrhythmic prophylaxis with procainamide in acute myocardial infarction.
    The New England journal of medicine, 1969, Dec-04, Volume: 281, Issue:23

    Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Blood Pressure; Clinical Trials as Topic; Electrocardiogr

1969
Prophylaxis of ventricular dysrhythmias following acute myocardial infarction: a double-blind trial of continuous intravenous infusion of lignocaine.
    Guy's Hospital reports, 1971, Volume: 120, Issue:1

    Topics: Acute Disease; Arrhythmias, Cardiac; Clinical Trials as Topic; Female; Humans; Injections, Intraveno

1971
Lignocaine therapy for ventricular ectopic activity after acute myocardial infarction: a double-blind trial.
    British medical journal, 1971, Sep-18, Volume: 3, Issue:5776

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Gas Analysis; Clinical Trials as Topic; Elec

1971
Antiarrhythmic prophylaxis in acute myocardial infarction.
    The New England journal of medicine, 1971, Oct-28, Volume: 285, Issue:18

    Topics: Acute Disease; Administration, Oral; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Care U

1971

Other Studies

177 other studies available for lidocaine and Acute Disease

ArticleYear
Efficacy of intra-arterial lidocaine infusion in the treatment of cerulein-induced acute pancreatitis.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2020, Volume: 29, Issue:5

    Topics: Acute Disease; Animals; Ceruletide; Infusions, Intra-Arterial; Lidocaine; Pancreas; Pancreatitis; Ra

2020
Greater palatine block in the treatment of acute epistaxis.
    Annals of the Royal College of Surgeons of England, 2015, Volume: 97, Issue:2

    Topics: Acute Disease; Anesthetics, Local; Cautery; Epinephrine; Epistaxis; Humans; Injections; Lidocaine; P

2015
Hoigne syndrome: a little-known adverse effect of lidocaine.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:3

    Topics: Acute Disease; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Syndrome; Young

2016
A new endovascular strategy utilizing a hybrid procedure for long segmental occlusion by acute arterial thromboembolism in the lower extremity.
    Japanese journal of radiology, 2016, Volume: 34, Issue:7

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Computed Tomography Angiography;

2016
Is topical lignocaine for pain relief in acute otitis media really effective?
    Archives of disease in childhood, 2008, Volume: 93, Issue:8

    Topics: Acute Disease; Administration, Topical; Anesthetics, Local; Child; Humans; Lidocaine; Otitis Media;

2008
Lipopolysaccharide-induced hypotension is mediated by a neural pathway involving the vagus nerve, the nucleus tractus solitarius and alpha-adrenergic receptors in the preoptic anterior hypothalamic area.
    Journal of neuroimmunology, 2008, Oct-15, Volume: 203, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Hypotension; Lidocaine; Li

2008
A lacrimal sac abscess incision and drainage technique.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2008, Volume: 126, Issue:9

    Topics: Abscess; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics,

2008
Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures.
    Brain & development, 2009, Volume: 31, Issue:8

    Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography

2009
[Convulsions in the operating room in a man with AIDS].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Acute Disease; AIDS-Related Opportunistic Infections; Anti-HIV A

2009
[Acute transient ataxia caused by local lidocaine injection during insertion of a pleural catheter].
    Archivos de bronconeumologia, 2009, Volume: 45, Issue:9

    Topics: Acute Disease; Anesthetics, Local; Catheterization; Cerebellar Ataxia; Community-Acquired Infections

2009
[Acute bilateral palpebral necrosis: a rare complication of local anaesthesia].
    Annales de dermatologie et de venereologie, 2010, Volume: 137, Issue:1

    Topics: Acute Disease; Adolescent; Anesthetics, Local; Chalazion; Corneal Ulcer; Epinephrine; Eyelid Disease

2010
[Acute bilateral palpebral necrosis: a rare complication of local anaesthesia].
    Annales de dermatologie et de venereologie, 2010, Volume: 137, Issue:1

    Topics: Acute Disease; Adolescent; Anesthetics, Local; Chalazion; Corneal Ulcer; Epinephrine; Eyelid Disease

2010
[Acute bilateral palpebral necrosis: a rare complication of local anaesthesia].
    Annales de dermatologie et de venereologie, 2010, Volume: 137, Issue:1

    Topics: Acute Disease; Adolescent; Anesthetics, Local; Chalazion; Corneal Ulcer; Epinephrine; Eyelid Disease

2010
[Acute bilateral palpebral necrosis: a rare complication of local anaesthesia].
    Annales de dermatologie et de venereologie, 2010, Volume: 137, Issue:1

    Topics: Acute Disease; Adolescent; Anesthetics, Local; Chalazion; Corneal Ulcer; Epinephrine; Eyelid Disease

2010
Acute bilateral retinal hemorrhages and unilateral sixth cranial nerve palsy after inadvertent epidural anaesthetic injection and subsequent dural puncture.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2010, Volume: 45, Issue:5

    Topics: Abducens Nerve Diseases; Acute Disease; Analgesia, Epidural; Anesthetics, Local; Diplopia; Female; F

2010
Epidural analgesia provides better pain management after live liver donation: a retrospective study.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2011, Volume: 17, Issue:3

    Topics: Acute Disease; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesth

2011
Successful thrombolysis and spasmolysis of acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets.
    Cardiovascular and interventional radiology, 2011, Volume: 34, Issue:5

    Topics: Acute Disease; Adult; Alprostadil; Anesthetics, Local; Anti-Anxiety Agents; Fibrinolytic Agents; Flu

2011
Acute bullous irritant contact dermatitis caused by EMLA® cream.
    Contact dermatitis, 2011, Volume: 65, Issue:3

    Topics: Acute Disease; Anesthetics, Local; Blister; Dermatitis, Irritant; Drug Hypersensitivity; Eczema; Emo

2011
Acute lumbar spondylolysis in intercollegiate athletes.
    Journal of spinal disorders & techniques, 2012, Volume: 25, Issue:8

    Topics: Acute Disease; Athletes; Athletic Injuries; Bone Screws; Disability Evaluation; Female; Humans; Inje

2012
[Estimation of efficacy of Hexalyse used for the treatment of acute pharyngitis].
    Vestnik otorinolaringologii, 2011, Issue:6

    Topics: Acute Disease; Adult; Anesthetics, Local; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Stero

2011
Problems related to epidural analgesia for postoperative pain control.
    Annals of the Academy of Medicine, Singapore, 2002, Volume: 31, Issue:4

    Topics: Acute Disease; Adult; Aged; Amides; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Catheteri

2002
Acute pancreatitis possible initial triggering mechanism and prophylaxis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2003, Volume: 3, Issue:6

    Topics: Acute Disease; Anesthetics, Local; Animals; Disease Models, Animal; Duodenum; Lidocaine; Male; Pancr

2003
[Use of the drug otipax in acute otitis media in newborns and infants].
    Vestnik otorinolaringologii, 2004, Issue:4

    Topics: Acute Disease; Age Factors; Aminopyrine; Drug Combinations; Female; Humans; Infant; Infant, Newborn;

2004
Mexiletine protects myocardium during acute ischemia by opening sarcolemmal K-ATP channel: studies in closed-chest acute ischemia model in rabbits.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:6

    Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; ATP-Binding Cassette Transporters; Disease Models, A

2004
Experimental acute lung injury. Effects of methylprednisolone and lidocaine on histopathology and neutrophils.
    Saudi medical journal, 2004, Volume: 25, Issue:12

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Chemotaxis, Leukocyte; Hydrochloric Acid; Lidocain

2004
Plain talk about wound pain.
    Ostomy/wound management, 2005, Volume: 51, Issue:11A Suppl

    Topics: Acute Disease; Anesthetics, Local; Attitude to Health; Chronic Disease; Humans; Lidocaine; Nursing A

2005
Transdermal Lidoderm for acute headache?
    Headache, 2006, Volume: 46, Issue:4

    Topics: Acute Disease; Administration, Cutaneous; Anesthetics, Local; Headache; Humans; Lidocaine

2006
Acute parotiditis and facial nerve palsy--unusual side effects of Xylocaine spray.
    Endoscopy, 2007, Volume: 39 Suppl 1

    Topics: Acute Disease; Anesthetics, Local; Dyspepsia; Endoscopy, Digestive System; Facial Paralysis; Female;

2007
Superior laryngeal neuralgia after acute laryngitis and treatment with a single injection of a local anesthetic.
    Archives of otolaryngology--head & neck surgery, 2007, Volume: 133, Issue:9

    Topics: Acute Disease; Adult; Anesthetics, Local; Epinephrine; Humans; Injections; Laryngeal Nerves; Laryngi

2007
Local anesthetic treatment significantly attenuates acute pain responding but does not prevent the neonatal injury-induced reduction in adult spinal behavioral plasticity.
    Behavioral neuroscience, 2007, Volume: 121, Issue:5

    Topics: Acute Disease; Anesthetics, Local; Animals; Animals, Newborn; Behavior, Animal; Electroshock; Inject

2007
Interleukin-8 is increased in gingival crevicular fluid from patients with acute pulpitis.
    Journal of endodontics, 2008, Volume: 34, Issue:2

    Topics: Acute Disease; Adult; Anesthetics, Local; Female; Gingival Crevicular Fluid; Humans; Interleukin-8;

2008
[Allergic contact dermatitis from lidocaine in ear drops].
    Actas dermo-sifiliograficas, 2008, Volume: 99, Issue:5

    Topics: Acute Disease; Aged; Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Ear; Face; Hu

2008
[Treatment of acute myocardial infarction].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1980, Apr-10, Volume: 100, Issue:10

    Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Humans; Hyaluronoglucosaminidase;

1980
[Therapeutic and preventive effect of oral lidocaine in extrasystole].
    Vutreshni bolesti, 1982, Volume: 21, Issue:6

    Topics: Acute Disease; Administration, Oral; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Dru

1982
Paranoid psychosis induced by tocainide.
    British medical journal (Clinical research ed.), 1984, Feb-25, Volume: 288, Issue:6417

    Topics: Acute Disease; Anti-Arrhythmia Agents; Humans; Lidocaine; Male; Middle Aged; Paranoid Disorders; Tim

1984
[Use of lidocaine peridural anesthesia in patients in the acute phase of a myocardial infarct].
    Kardiologiia, 1984, Volume: 24, Issue:8

    Topics: Acute Disease; Aged; Anesthesia, Epidural; Blood Pressure; Cardiac Output; Female; Heart Rate; Human

1984
[Prophylaxis of primary ventricular fibrillation in the acute phase of acute myocardial infarct].
    Revue medicale de Bruxelles, 1984, Volume: 5, Issue:8

    Topics: Acute Disease; Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation

1984
Respiratory obstruction following vocal cord injection of Teflon paste.
    Anaesthesia, 1984, Volume: 39, Issue:12

    Topics: Acute Disease; Airway Obstruction; Humans; Lidocaine; Male; Middle Aged; Polytetrafluoroethylene; Po

1984
[Clinical usefulness of celiac plexus block].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1984, Jun-15, Volume: 37, Issue:12

    Topics: Acute Disease; Autonomic Nerve Block; Celiac Plexus; Humans; Intestinal Obstruction; Intestinal Pseu

1984
Saliva concentrations of lignocaine in patients with acute myocardial ischaemia.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:2

    Topics: Acute Disease; Adult; Aged; Coronary Disease; Humans; Lidocaine; Male; Middle Aged; Saliva; Time Fac

1983
Protective effect of lidocaine in acute cerebral ischemia induced by air embolism.
    Journal of neurosurgery, 1984, Volume: 60, Issue:2

    Topics: Acute Disease; Animals; Brain; Brain Ischemia; Cats; Embolism, Air; Evoked Potentials, Somatosensory

1984
[Intensive monitoring ward for coronary patients].
    Kardiologiia, 1984, Volume: 24, Issue:1

    Topics: Acute Disease; Coronary Care Units; Hospitalization; Humans; Lidocaine; Monitoring, Physiologic; Myo

1984
Acute pulmonary edema after regional anesthesia with lidocaine and epinephrine in a patient with chronic renal failure.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:3

    Topics: Acute Disease; Adult; Anesthesia, Conduction; Epinephrine; Humans; Kidney Failure, Chronic; Lidocain

1984
A simple method of treatment for the acute headache.
    Headache, 1984, Volume: 24, Issue:1

    Topics: Acute Disease; Headache; Humans; Injections, Intravenous; Lidocaine; Procaine

1984
[The immediate treatment of acute myocardial infarct].
    Medizinische Klinik, 1981, Mar-27, Volume: 76, Issue:7

    Topics: Acute Disease; Arrhythmias, Cardiac; First Aid; Furosemide; Hemodynamics; Humans; Isosorbide Dinitra

1981
Should prophylactic antiarrhythmic drug therapy be used in acute myocardial infarction?
    JAMA, 1982, Apr-09, Volume: 247, Issue:14

    Topics: Acute Disease; Humans; Lidocaine; Metabolism; Methods; Myocardial Infarction; Time Factors; Ventricu

1982
[Emergency therapy of cardiac arrhythmias. Statistico-clinical evaluation of verapamil (clinical note)].
    Minerva cardioangiologica, 1982, Volume: 30, Issue:4

    Topics: Acute Disease; Adult; Aged; Ajmaline; Arrhythmias, Cardiac; Bunaftine; Female; Humans; Lidocaine; Ma

1982
[The place of lidocaine in the treatment of acute attacks of intracranial hypertension].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1982, Volume: 23, Issue:C

    Topics: Acute Disease; Adult; Aged; Female; Humans; Intracranial Pressure; Lidocaine; Male; Middle Aged; Pse

1982
[Standard therapy of acute myocardial infarction.--I: General management (author's transl)].
    Herz, 1981, Volume: 6, Issue:1

    Topics: Acute Disease; Analgesics; Arrhythmias, Cardiac; Coronary Care Units; Early Ambulation; Hemodynamics

1981
The effects of lidocaine on intracellular and extracellular potentials, activation, and ventricular arrhythmias during acute regional ischemia in the isolated porcine heart.
    Circulation research, 1981, Volume: 49, Issue:3

    Topics: Action Potentials; Acute Disease; Animals; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Corona

1981
[Anti-arrhythmia effect of flecainide in acute myocardial infarct in comparison with lidocaine].
    Die Medizinische Welt, 1981, Jul-17, Volume: 32, Issue:29

    Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Dogs; Flecainide; Lidocaine; Myocardial Infarction; Pi

1981
Recurrence of ventricular fibrillation in acute ischemic heart disease.
    Circulation, 1981, Volume: 64, Issue:6

    Topics: Acute Disease; Anti-Arrhythmia Agents; Coronary Disease; Female; Heart Arrest; Humans; Lidocaine; Ma

1981
Improved observational method for studying therapeutic efficacy. Suggestive evidence that lidocaine prophylaxis prevents death in acute myocardial infarction.
    JAMA, 1981, Nov-27, Volume: 246, Issue:21

    Topics: Acute Disease; Aged; Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Lidocaine; Male;

1981
[Treatment of peripheral lesions of the facial nerve with a lidocaine block].
    Sovetskaia meditsina, 1980, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Cervical Plexus; Facial Nerve; Facial Neuralgia; Facial Paralysis;

1980
[Dangerous bradycardia after xylocaine treatment of acute myocardial infarct].
    Kardiologia polska, 1980, Volume: 23, Issue:5

    Topics: Acute Disease; Bradycardia; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction

1980
[Intramuscular administration of lignocaine for prevention of life-threatening arrhythmia in acute myocardial infarct].
    Kardiologia polska, 1980, Volume: 23, Issue:7

    Topics: Acute Disease; Adult; Aged; Female; Humans; Injections, Intramuscular; Lidocaine; Male; Middle Aged;

1980
First-aid treatment for acute coronary thrombosis.
    British medical journal, 1980, Jan-26, Volume: 280, Issue:6209

    Topics: Acute Disease; Coronary Disease; Digoxin; Humans; Lidocaine; Tachycardia; Ventricular Fibrillation

1980
Postpartum acute subdural hematoma; a probable complication of saddle block analgesia.
    Neurosurgery, 1980, Volume: 7, Issue:4

    Topics: Acute Disease; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Female; Hematoma, Subdural; Human

1980
The treatment of acute myocardial infarction.
    Scottish medical journal, 1980, Volume: 25, Issue:3

    Topics: Acute Disease; Atropine; Bradycardia; Humans; Lidocaine; Myocardial Infarction; Surveys and Question

1980
[Drug metabolism in patients with liver disease (author's transl)].
    Leber, Magen, Darm, 1980, Volume: 10, Issue:5

    Topics: Acute Disease; Adult; Antipyrine; Biological Availability; Biotransformation; Cholestasis; Female; H

1980
Facilitation of reentry by lidocaine in canine myocardial infarction.
    Acta physiologica Hungarica, 1994, Volume: 82, Issue:3

    Topics: Acute Disease; Animals; Chronic Disease; Dogs; Electrocardiography; Electrophysiology; Heart Conduct

1994
Effect of vasoconstrictive agents added to lidocaine on intravenous lidocaine-induced convulsions in rats.
    Anesthesiology, 1995, Volume: 82, Issue:2

    Topics: Acute Disease; Animals; Blood Gas Analysis; Blood Glucose; Blood Pressure; Dose-Response Relationshi

1995
Treatment of the cutaneous pain of acute herpes zoster with 9% lidocaine (base) in petrolatum/paraffin ointment.
    Journal of the American Academy of Dermatology, 1994, Volume: 30, Issue:5 Pt 1

    Topics: Acute Disease; Administration, Cutaneous; Adult; Drug Evaluation; Female; Herpes Zoster; Humans; Lid

1994
Ischemia enhances use-dependent sodium channel blockade by pilsicainide, a class IC antiarrhythmic agent.
    Journal of the American College of Cardiology, 1994, Volume: 23, Issue:6

    Topics: Acute Disease; Aged; Analysis of Variance; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chi-Square

1994
Advantages and limitations of metaanalytic regressions of clinical trials data.
    The Online journal of current clinical trials, 1994, Jun-04, Volume: Doc No 134

    Topics: Acute Disease; Confounding Factors, Epidemiologic; Crohn Disease; Humans; Immunosuppression Therapy;

1994
A prospective study for validation of Bayesian prediction approach to adjust individual lidocaine dosage.
    International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:1

    Topics: Acute Disease; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Bayes Theorem; Female; Humans; Infusio

1994
Lidocaine and acute coronary care.
    Critical care medicine, 1993, Volume: 21, Issue:2

    Topics: Acute Disease; Arrhythmias, Cardiac; Coronary Care Units; Humans; Lidocaine

1993
Cortical facilitatory action on centralis lateralis thalamic activity during the development of carrageenin-produced inflammation.
    Archives of medical research, 1996,Autumn, Volume: 27, Issue:3

    Topics: Acute Disease; Afferent Pathways; Anesthetics, Local; Animals; Carrageenan; Chronic Disease; Edema;

1996
Intranasal lidocaine for treatment of migraine.
    JAMA, 1996, Nov-20, Volume: 276, Issue:19

    Topics: Acute Disease; Administration, Intranasal; Humans; Lidocaine; Migraine Disorders

1996
Intranasal lidocaine for treatment of migraine.
    JAMA, 1996, Nov-20, Volume: 276, Issue:19

    Topics: Acute Disease; Diagnosis, Differential; Humans; Lidocaine; Migraine Disorders; Tomography, X-Ray Com

1996
Intranasal lidocaine for treatment of migraine.
    JAMA, 1996, Nov-20, Volume: 276, Issue:19

    Topics: Acute Disease; Administration, Intranasal; Humans; Lidocaine; Migraine Disorders

1996
Intranasal lidocaine for treatment of migraine.
    JAMA, 1996, Nov-20, Volume: 276, Issue:19

    Topics: Acute Disease; Administration, Inhalation; Humans; Lidocaine; Migraine Disorders

1996
Sphenopalatine ganglion block: a safe and easy method for the management of orofacial pain.
    Cranio : the journal of craniomandibular practice, 1995, Volume: 13, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Anesthetics, Local; Autonomic Nerve Block; Chronic Diseas

1995
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste

1997
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste

1997
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste

1997
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste

1997
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste

1997
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste

1997
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste

1997
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste

1997
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste

1997
[Perioperative management for acute abdominal aortic obstruction in a patient with acute myocardial reinfarction associated with acute renal failure].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:9

    Topics: Acute Disease; Acute Kidney Injury; Aged; Anesthesia, General; Anesthetics, Combined; Aorta, Abdomin

1997
Tumescent infiltration of corticosteroids, lidocaine, and epinephrine into dermatomes of acute herpetic pain or postherpetic neuralgia.
    Archives of dermatology, 1998, Volume: 134, Issue:3

    Topics: Acute Disease; Anesthetics, Local; Epinephrine; Glucocorticoids; Herpes Zoster; Humans; Injections;

1998
Hypotension following acute hypovolaemia depends on the caudal midline medulla.
    Neuroreport, 1998, Jun-01, Volume: 9, Issue:8

    Topics: Acute Disease; Anesthetics, Local; Animals; Blood Pressure; Cobalt; Hemorrhage; Hypotension; Lidocai

1998
Cellular mechanisms underlying spontaneous interictal spikes in an acute model of focal cortical epileptogenesis.
    Neuroscience, 1999, Volume: 88, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Acute Disease;

1999
Sight-threatening acute orbital swelling from peribulbar local anesthesia.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:3

    Topics: Acute Disease; Aged; Anesthetics, Local; Drug Hypersensitivity; Edema; Female; Follow-Up Studies; Gl

1999
[The patient with back pain and the family physician. Problem solving with simple methods].
    MMW Fortschritte der Medizin, 1999, Jun-03, Volume: 141, Issue:22

    Topics: Acute Disease; Anesthetics, Local; Back Pain; Chiropractic; Humans; Lidocaine; Male; Manipulation, S

1999
Central retinal artery occlusion after a local anesthetic with adrenaline on nasal mucosa.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2000, Volume: 20, Issue:4

    Topics: Acute Disease; Aged; Anesthetics, Local; Blindness; Drug Combinations; Epinephrine; Humans; Lacrimal

2000
The influence of lidocaine on the permeability of the blood-cerebrospinal fluid barrier in experimental acute hypercapnia in the rabbit.
    Acta neurobiologiae experimentalis, 2001, Volume: 61, Issue:2

    Topics: Acute Disease; Anesthetics, Local; Animals; Anti-Bacterial Agents; Blood Pressure; Blood-Brain Barri

2001
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Intra-articular lidocaine for acute anterior shoulder dislocation reduction.
    Emergency medicine journal : EMJ, 2002, Volume: 19, Issue:2

    Topics: Acute Disease; Anesthetics, Local; Evidence-Based Medicine; Humans; Injections, Intra-Articular; Lid

2002
Intrathecal lidocaine prevents cardiovascular collapse and neurogenic pulmonary edema in a rat model of acute intracranial hypertension.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:4

    Topics: Acute Disease; Anesthetics, Local; Animals; Blood Pressure; Brain; Electrocardiography; Heart Rate;

2002
[Emergencies in the practice. Acute lumbago: diagnosis and therapy].
    MMW Fortschritte der Medizin, 2002, Feb-28, Volume: 144, Issue:9

    Topics: Acute Disease; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents; Chiropractic; Diagn

2002
Temporary bilateral blindness after acute lidocaine toxicity.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:1

    Topics: Acute Disease; Adult; Anesthetics, Local; Blindness; Female; Fractures, Bone; GABA Modulators; Hand

2002
Negative inotropic effect of lidocaine in patients with coronary arterial disease and normal subjects.
    Chest, 1977, Volume: 71, Issue:2

    Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Angina Pectoris; Coronary Disease; Depression, Ch

1977
The use of buffered lignocaine solution in the presence of acute inflammation.
    Journal of dentistry, 1977, Volume: 5, Issue:2

    Topics: Acute Disease; Anesthesia, Dental; Anesthesia, Local; Buffers; Humans; Hydrogen-Ion Concentration; L

1977
[Effectiveness and comparative evaluation of various means of arrhythmia prophylaxis in acute period of myocardial infarction].
    Terapevticheskii arkhiv, 1979, Volume: 51, Issue:1

    Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Female; Humans; Lidocaine; Male; M

1979
[The treatment of acute cardiac dysrhythmias with atenolol (Tenormin) particularly after myocardial infarction (author's transl)].
    Zeitschrift fur Kardiologie, 1978, Volume: 67, Issue:4

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Atenolol; Atrial Fibrillation; Atrial Flutter; Car

1978
Rapid and accurate diagnosis of acute cholecystitis with 99mTc-HIDA cholescintigraphy.
    AJR. American journal of roentgenology, 1979, Volume: 132, Issue:4

    Topics: Acetates; Acute Disease; Adult; Cholecystitis; Cholelithiasis; Cystic Duct; Diagnosis, Differential;

1979
Relieving pain with nerve blocks.
    Geriatrics, 1978, Volume: 33, Issue:4

    Topics: Acute Disease; Aged; Back Pain; Bursitis; Humans; Intervertebral Disc; Joint Diseases; Lidocaine; Mi

1978
[Pharmacological treatment of arrhythmia following acute myocardial infarct].
    Kardiologia polska, 1975, Volume: 18, Issue:1

    Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bretylium Compounds; Humans; Lidoc

1975
[Myocardial infarct in the municipal hospital. Report on 1087 cases].
    Schweizerische medizinische Wochenschrift. Supplementum, 1977, Volume: 107 Suppl 6

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Creatine Kinase; Exercise Test; Female; Hemodynami

1977
[Pharmacokinetics of lidocaine after intramuscular injection in patients with acute myocardial infarction (author's transl)].
    Zeitschrift fur Kardiologie, 1979, Volume: 68, Issue:3

    Topics: Acute Disease; Arrhythmias, Cardiac; Half-Life; Humans; Injections, Intramuscular; Lidocaine; Myocar

1979
Premature ventricular contractions in acute myocardial infarction. Correlation between their origin and the location of infarction.
    Journal of electrocardiology, 1979, Volume: 12, Issue:2

    Topics: Acute Disease; Arrhythmias, Cardiac; Electrocardiography; Humans; Lidocaine; Myocardial Infarction

1979
[Lidocaine pharmacokinetics and substantiation of the new method of its administration in myocardial infarct].
    Kardiologiia, 1979, Volume: 19, Issue:7

    Topics: Acute Disease; Adult; Aged; Biological Availability; Female; Humans; Infusions, Parenteral; Isotonic

1979
[Preventive effectiveness of verapamil in ventricular fibrillation in the first 24 hours after myocardial infarct].
    Bollettino della Societa italiana di cardiologia, 1979, Volume: 24, Issue:3

    Topics: Acute Disease; Adult; Aged; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Ven

1979
[Arrhythmias during catheterization of patients with acute myocardial infarction (author's transl)].
    Wiener klinische Wochenschrift, 1977, Dec-09, Volume: 89, Issue:23

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Cardiac Catheterization; Female; Humans; Lidocaine

1977
Xylocaine treatment in experimental pancreatitis in pigs.
    Scandinavian journal of gastroenterology, 1978, Volume: 13, Issue:7

    Topics: Acute Disease; Animals; Drug Evaluation, Preclinical; Hemorrhage; Infusions, Parenteral; Lidocaine;

1978
[Current viewpoints on prevention and treatment of ventricular fibrillation in acute heart infarct].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1978, Volume: 40, Issue:5

    Topics: Acute Disease; Digoxin; Drug Therapy, Combination; Electric Countershock; Humans; Lidocaine; Myocard

1978
[Primary ventricular fibrillation during the acute phase of myocardial infarction (author's transl)].
    Annales de cardiologie et d'angeiologie, 1978, Volume: 27, Issue:6

    Topics: Acute Disease; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Humans; Lidocaine; Middle Aged; Myo

1978
[Stosstherapy with steroid-containing combination preparation "Ambene" in the acute stages of rheumatic diseases].
    MMW, Munchener medizinische Wochenschrift, 1975, Mar-07, Volume: 117, Issue:10

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aluminum; Aminopyrine; Anti-Inflammato

1975
Restricted lignocaine prophylaxis in acute myocardial infarction.
    Acta medica Scandinavica, 1977, Volume: 201, Issue:1-2

    Topics: Acute Disease; Adult; Aged; Coronary Care Units; Humans; Lidocaine; Male; Middle Aged; Myocardial In

1977
[Lidocaine in acute myocardial infarction].
    Harefuah, 1977, May-01, Volume: 92, Issue:9

    Topics: Acute Disease; Humans; Lidocaine; Myocardial Infarction

1977
Ventricular fibrillation and acute myocardial infarction.
    Comprehensive therapy, 1977, Volume: 3, Issue:8

    Topics: Acute Disease; Adult; Aged; Electric Countershock; Humans; Lidocaine; Middle Aged; Myocardial Infarc

1977
Acute myocardial infarction in an American traveler in China.
    Archives of internal medicine, 1976, Volume: 136, Issue:7

    Topics: Acute Disease; Adult; China; Emergency Medical Services; Heart Arrest; Humans; Infusions, Parenteral

1976
Comparative effects of lidocaine and procainamide on acutely impaired hemodynamics.
    The American journal of medicine, 1976, Volume: 61, Issue:2

    Topics: Acute Disease; Adult; Aged; Blood Pressure; Cardiac Output; Depression, Chemical; Electrocardiograph

1976
Influence of viral hepatitis on the disposition of two compounds with high hepatic clearance: lidocaine and indocyanine green.
    Clinical pharmacology and therapeutics, 1976, Volume: 20, Issue:3

    Topics: Acute Disease; Adult; Half-Life; Hepatitis A; Humans; Indocyanine Green; Kinetics; Lidocaine; Liver;

1976
Significance of ventricular premature beats as a potential life threatening arrhythmia in acute myocardial infarction.
    Indian heart journal, 1976, Volume: 28, Issue:2

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Humans; Lidocaine; Middle Aged; Myocardial Infarct

1976
[Lidocaine therapy in the early phase of arrhythmia after acute myocardial infarct without influence on the fibrillatory threshold and on the spontaneous ventricular fibrillation of the heart].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 2

    Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Dogs; Lidocaine; Myocardial Infarction; Time Factors;

1976
[Clinical and experimental contribution to the pathogenesis of acute life-threatening incidents following neck anesthesia].
    Schweizerische medizinische Wochenschrift, 1975, Jan-11, Volume: 105, Issue:2

    Topics: Acute Disease; Anaphylaxis; Anesthesia, Epidural; Anesthesia, Local; Anesthetics; Drug Hypersensitiv

1975
[Editorial: Prevention of fatal arrhythmia].
    Lakartidningen, 1975, Jun-18, Volume: 72, Issue:25

    Topics: Acute Disease; Arrhythmias, Cardiac; Humans; Lidocaine; Myocardial Infarction

1975
Pharmacological modification of arrhythmias after experimentally induced acute myocardial infarction. Drugs acting on the nervous system.
    Circulation, 1975, Volume: 52, Issue:6 Suppl

    Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Chlordiaz

1975
[Letter: The value of preventive lidocaine therapy in acute myocardial infarct].
    Orvosi hetilap, 1975, Dec-14, Volume: 116, Issue:50

    Topics: Acute Disease; Humans; Lidocaine; Myocardial Infarction

1975
[Effect of mesocaine on the heart conduction system in acute myocardial infarct].
    Vnitrni lekarstvi, 1975, Volume: 21, Issue:11

    Topics: Acute Disease; Adult; Aged; Female; Heart Conduction System; Heart Rate; Humans; Lidocaine; Male; Mi

1975
[Possibilities of a routine prevention of arrhythmia in the early phase of acute myocardial infarct].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1975, Oct-01, Volume: 30, Issue:19

    Topics: Acute Disease; Arrhythmias, Cardiac; Heart Block; Humans; Injections, Intravenous; Lidocaine; Myocar

1975
The management of acute myocardial infarction.
    Comprehensive therapy, 1975, Volume: 1, Issue:7

    Topics: Acute Disease; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Glycosides; Humans; Lidocaine

1975
Routine prophylactic lidocaine administration in acute myocardial infarction. An idea whose time is all but gone?
    Circulation, 1992, Volume: 86, Issue:3

    Topics: Acute Disease; Cardiology; Humans; Lidocaine; Myocardial Infarction

1992
Predictive performance of Bayesian and nonlinear least-squares regression programs for lidocaine.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:4

    Topics: Acute Disease; Arrhythmias, Cardiac; Bayes Theorem; Chronic Disease; Humans; Least-Squares Analysis;

1992
Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:6

    Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Chronic Disease; Female; Heart Ventricles; Humans; Infusi

1992
Treatment for herpes zoster ophthalmicus: stellate ganglion block as a treatment for acute pain and prevention of postherpetic neuralgia.
    Annals of ophthalmology, 1991, Volume: 23, Issue:5

    Topics: Acute Disease; Aged; Aged, 80 and over; Autonomic Nerve Block; Bupivacaine; Female; Herpes Zoster Op

1991
Acute MI management in the 1990s.
    Hospital practice (Office ed.), 1990, Jul-15, Volume: 25, Issue:7

    Topics: Acute Disease; Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Angiotensin-Converting E

1990
Effects of acute hypermagnesemia on the threshold for lidocaine-induced seizures in the rat.
    American journal of obstetrics and gynecology, 1991, Volume: 164, Issue:2

    Topics: Acute Disease; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography;

1991
Medical treatment of acute spinal cord injuries.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1990, Volume: 190, Issue:2

    Topics: Acute Disease; Animals; Cats; Female; Lidocaine; Male; Naloxone; Spinal Cord Injuries; Thyrotropin-R

1990
Contact sensitivity to lignocaine and prilocaine.
    Contact dermatitis, 1990, Volume: 23, Issue:2

    Topics: Acute Disease; Administration, Topical; Adult; Cross Reactions; Dermatitis, Contact; Drug Eruptions;

1990
[Use of sacral anesthesia, prolonged by opiates, in patients with acute proctologic diseases].
    Klinicheskaia khirurgiia, 1989, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, Caudal; Anesthesia, Epidural; Anus Diseases; Fem

1989
[Transient acute respiratory failure and thoracic epidural anesthesia].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:2

    Topics: Acute Disease; Anesthesia, Epidural; Bupivacaine; Female; Fentanyl; Horner Syndrome; Humans; Intraop

1989
The pharmacokinetics of R- and S-tocainide in patients with acute ventricular arrhythmias.
    British journal of clinical pharmacology, 1986, Volume: 21, Issue:2

    Topics: Acute Disease; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Humans; Kinetics; Lidocai

1986
[Inhalation of lidocaine in pulmonology].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:12

    Topics: Acute Disease; Administration, Inhalation; Adult; Bronchitis; Cough; Dyspnea; Female; Humans; Hyperv

1988
Reduction of experimental intracranial hypertension by lidocaine.
    Neurosurgery, 1987, Volume: 20, Issue:4

    Topics: Acute Disease; Animals; Blood Pressure; Brain Ischemia; Cats; Embolism, Air; Female; Infusions, Intr

1987
Treatment of an acute anterior disk displacement in the temporomandibular joint. A case report.
    Physical therapy, 1987, Volume: 67, Issue:8

    Topics: Acute Disease; Aged; Dexamethasone; Female; Humans; Iontophoresis; Lidocaine; Physical Therapy Modal

1987
Changes in lignocaine disposition during long-term infusion in patients with acute ventricular arrhythmias.
    Therapeutic drug monitoring, 1987, Volume: 9, Issue:3

    Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Bayes Theorem; Female; Humans; Lidocaine; Male; Metabolic

1987
[Prevention, using alpha-tocopherol and lidocaine, of damage to the monooxygenase system activity and ultrastructure of hepatocytes following acute ischemia of the liver].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 104, Issue:12

    Topics: Acute Disease; Animals; Ischemia; Lidocaine; Liver; Male; Oxygenases; Rats; Vitamin E

1987
[Drugs in acute heart disease. 1].
    Sygeplejersken, 1985, Mar-13, Volume: 85, Issue:11

    Topics: Acute Disease; Epinephrine; Heart Diseases; Humans; Lidocaine

1985
Anesthesia for acute epiglottitis.
    Anesthesiology, 1986, Volume: 64, Issue:5

    Topics: Acute Disease; Anesthesia; Child, Preschool; Epiglottitis; Humans; Intubation, Intratracheal; Laryng

1986
Workshop II: Cost containment issues in acute myocardial infarction and coronary care management--points of view.
    The American journal of cardiology, 1985, Aug-23, Volume: 56, Issue:5

    Topics: Acute Disease; Arrhythmias, Cardiac; Coronary Care Units; Cost Control; Health Workforce; Heart Fail

1985
Acute calcification in the fingers.
    Journal of hand surgery (Edinburgh, Scotland), 1985, Volume: 10, Issue:2

    Topics: Acute Disease; Calcinosis; Female; Finger Joint; Humans; Lidocaine; Middle Aged; Radiography; Splint

1985
A treatment of herpes zoster.
    The Practitioner, 1985, Volume: 229, Issue:1406

    Topics: Acute Disease; Adolescent; Adult; Aged; Autonomic Nerve Block; Female; Herpes Zoster; Humans; Lidoca

1985
Acute phase of myocardial infarction.
    Lancet (London, England), 1971, Sep-04, Volume: 2, Issue:7723

    Topics: Acute Disease; Adult; Age Factors; Aged; Arrhythmias, Cardiac; Atropine; Cardiac Complexes, Prematur

1971
Initial metabolic and hormonal response to acute myocardial infarction.
    Lancet (London, England), 1974, Feb-23, Volume: 1, Issue:7852

    Topics: Acute Disease; Adult; Aged; Blood Glucose; Blood Specimen Collection; Catecholamines; Cholesterol; C

1974
[Arrhythmias in acute myocardial infarct].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1973, Volume: 54, Issue:10

    Topics: Acidosis; Acute Disease; Arrhythmias, Cardiac; Aspartic Acid; Atrial Fibrillation; Atrial Flutter; B

1973
[Combined drug therapy in highly acute attacks of pain in the course of rheumatic diseases].
    MMW, Munchener medizinische Wochenschrift, 1974, Jul-05, Volume: 116, Issue:27

    Topics: Acute Disease; Aminopyrine; Arthritis, Rheumatoid; Dexamethasone; Drug Combinations; Female; Humans;

1974
Amours M d',+AMOURS M: [Treatment of acute lumbalgia].
    Laval medical, 1969, Volume: 40, Issue:3

    Topics: Acute Disease; Back Pain; Drug Synergism; Female; Humans; Hydrocortisone; Injections; Intervertebral

1969
Management of acute myocardial infarction.
    The Journal of the Arkansas Medical Society, 1971, Volume: 68, Issue:3

    Topics: Acute Disease; Arkansas; Arrhythmias, Cardiac; Coronary Care Units; Heart Block; Humans; Hypotension

1971
[Respiratory effects of bone cement with a methyl-methacrylate basis (author's transl)].
    Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1974, Volume: 112, Issue:5

    Topics: Action Potentials; Acute Disease; Animals; Apnea; Bone Cements; Bronchodilator Agents; Dogs; Dose-Re

1974
Comparison of the effect of propranolol, lignocaine, and other drugs on normal and raised intraocular pressure in man.
    American journal of ophthalmology, 1971, Volume: 72, Issue:4

    Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesthetics, Local; C

1971
Effects of a long-acting antiarrhythmic agent--QX-572--on therapy resistant ventricular tachyarrhythmias.
    British heart journal, 1974, Volume: 36, Issue:8

    Topics: Acute Disease; Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure;

1974
[Hemodynamic effects of xylocaine and ajmaline in myocardial infarction].
    Archives des maladies du coeur et des vaisseaux, 1972, Volume: 65, Issue:10

    Topics: Acute Disease; Adult; Aged; Ajmaline; Cardiac Output; Central Venous Pressure; Heart Rate; Humans; L

1972
Acute sodium fluoride poisoning.
    JAMA, 1972, Nov-13, Volume: 222, Issue:7

    Topics: Acute Disease; Adult; Calcium; Diazepam; Diuretics; Electric Countershock; Esophageal Stenosis; Fluo

1972
Pre-hospital management of acute myocardial infarction.
    The Medical clinics of North America, 1973, Volume: 57, Issue:1

    Topics: Acute Disease; Anxiety; Atropine; Communication; Heart Massage; Heparin; Home Care Services; Humans;

1973
[Anti-arrhythmia agents. Prehospital therapy and prevention of arrhythmia in acute myocardial infarct. What advice should the general practitioner get?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Feb-10, Volume: 93, Issue:4

    Topics: Acute Disease; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Emergency Medical Services; F

1973
Experimental acute myocardial infarction. Characterization and treatment of the malignant premature ventricular contraction.
    Circulation, 1973, Volume: 47, Issue:3

    Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Atropine; Coronary Vessels; Dogs; Injections, Intraven

1973
Acute myocardial infarction occurring during continuous ECG recording.
    Acta medica Scandinavica, 1973, Volume: 193, Issue:3

    Topics: Acute Disease; Alanine Transaminase; Arrhythmias, Cardiac; Aspartate Aminotransferases; Coronary Car

1973
Blood lidocaine levels and kinetics following high-dose intramuscular administration.
    Circulation, 1973, Volume: 47, Issue:5

    Topics: Acute Disease; Adult; Aged; Arm; Buttocks; Humans; Injections, Intramuscular; Kinetics; Lidocaine; M

1973
[Use of xylocaine in the prevention and treatment of arrhythmias during an acute myocardial infarct].
    Wiener klinische Wochenschrift, 1973, Jun-08, Volume: 85, Issue:23

    Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Injections, Intraven

1973
Treatment of pain: organization of a pain clinic: treatment of acute herpes zoster.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, Conduction; Child; Follow-Up Studies; Ganglia, A

1973
[Anti-ischemic effect of lidocaine in the acute phase of myocardial infarct without shock].
    Orvosi hetilap, 1974, Mar-24, Volume: 115, Issue:12

    Topics: Acute Disease; Adult; Aged; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction

1974
Serum enzyme values following intramuscular administration of lidocaine.
    Archives of internal medicine, 1974, Volume: 134, Issue:1

    Topics: Acute Disease; Adult; Alanine Transaminase; Arrhythmias, Cardiac; Aspartate Aminotransferases; Creat

1974
Multiple episodes of ventricular fibrillation in acute myocardial infarction.
    Postgraduate medicine, 1972, Volume: 51, Issue:2

    Topics: Acute Disease; Electric Countershock; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; P

1972
Lidocaine in obstructive pulmonary disease.
    JAMA, 1972, Jun-12, Volume: 220, Issue:11

    Topics: Acute Disease; Chronic Disease; Humans; Injections, Intravenous; Lidocaine; Lung Diseases, Obstructi

1972
Limitations of lignocaine in control of early ventricular dysrhythmias complicating acute myocardial infarction.
    British heart journal, 1972, Volume: 34, Issue:9

    Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Heart Ventricles; Humans; Lidocaine; Myocardial Infarc

1972
Acute myocardial infarction complications and management.
    Polish medical journal, 1971, Volume: 10, Issue:5

    Topics: Acute Disease; Arrhythmias, Cardiac; Atropine; Digitalis Glycosides; Electric Countershock; Humans;

1971
[Lignocaine in the treatment of arrhythmia in acute myocardial infarct].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1971, Volume: 24, Issue:19

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Evaluation Studies as Topic; Female; Heart Ventric

1971
The use of epidural block in acute pancreatitis: a report of eight cases.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:5

    Topics: Acute Disease; Adult; Aged; Anesthesia, Spinal; Electrocardiography; Electrolytes; Female; Humans; L

1969
[Therapeutic results in acute reduction of hearing].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1969, Dec-22, Volume: 194, Issue:2

    Topics: Acute Disease; Autonomic Nerve Block; Deafness; Hearing; Hearing Disorders; Humans; Lidocaine; Nicot

1969
[Ventricular fibrillation in acute myocardial infarct. Apropos of 7 cases with recovery].
    Acta clinica Belgica, 1969, Volume: 24, Issue:4

    Topics: Acute Disease; Aged; Electric Countershock; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial

1969
Ventricular parasystole in acute myocardial infarction.
    British heart journal, 1970, Volume: 32, Issue:3

    Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Digitalis Glycosides; Electrocardiography; Female; Humans

1970
Some observations in the management of 300 cases of acute myocardial infarction treated in the intensive coronary care unit.
    The Journal of the Association of Physicians of India, 1970, Volume: 18, Issue:5

    Topics: Acute Disease; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atropine; Coronary Care Units; Female; Human

1970
[Acute cardiac arrhythmia].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1971, Jan-25, Volume: 26, Issue:4

    Topics: Acute Disease; Arrhythmias, Cardiac; Digitalis Glycosides; Electric Countershock; Female; Humans; Li

1971
Immediate treatment of myocardial infarction.
    Wisconsin medical journal, 1971, Volume: 70, Issue:4

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Atropine; Electrocardiography; Hospitalization; Hu

1971
[Personal experiences with prolonged administration of drip infusions of xylocaine in the early period of myocardial infarct].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1971, Jun-15, Volume: 24, Issue:12

    Topics: Acute Disease; Arrhythmias, Cardiac; Female; Humans; Infusions, Parenteral; Lidocaine; Male; Myocard

1971
Primary ventricular fibrillation complicating acute myocardial infarction.
    The American journal of cardiology, 1971, Volume: 27, Issue:4

    Topics: Acute Disease; Adult; Age Factors; Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans;

1971
[Lidocaine in the acute phase of myocardial infarct].
    Laval medical, 1971, Volume: 42, Issue:3

    Topics: Acute Disease; Humans; Lidocaine; Myocardial Infarction

1971
Atrial pacing to control heart rate and rhythm in acute cardiac conditions.
    Canadian Medical Association journal, 1971, May-22, Volume: 104, Issue:10

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Volume; Bradycardia; Cardiac Catheterization

1971
Pre-hospital phase of an acute coronary attack. Treatment with combination of intravenous and intramuscular lidocaine.
    Rocky Mountain medical journal, 1971, Volume: 68, Issue:4

    Topics: Acute Disease; Coronary Disease; Hospitalization; Humans; Injections, Intramuscular; Injections, Int

1971
[Adverse effects of lidocaine as an anti-arrhythmic drug].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1971, Apr-10, Volume: 91, Issue:10

    Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Lidocaine; Male; Mid

1971
Intractable hiccuping in acute myocardial infarction.
    British medical journal, 1971, May-29, Volume: 2, Issue:5760

    Topics: Acute Disease; Aged; Chlorpromazine; Hiccup; Humans; Injections, Intramuscular; Lidocaine; Male; Myo

1971
[Lidocaine as an anti-arrhythmia agent. Experiences with 68 patients].
    Ugeskrift for laeger, 1969, Mar-20, Volume: 131, Issue:12

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Injections, I

1969
The long-term prognosis for patients resuscitated after cardiac arrest. A follow-up study.
    American heart journal, 1969, Volume: 78, Issue:4

    Topics: Acute Disease; Adult; Aged; Coronary Disease; Follow-Up Studies; Heart Arrest; Heart Massage; Humans

1969