Page last updated: 2024-10-28

lidocaine and Acute Brain Injuries

lidocaine has been researched along with Acute Brain Injuries in 16 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Combined infusion of high doses of lidocaine and thiopental in a comatose patient induced major latency and amplitude BAEP changes, which progressed to complete BAEP abolition."3.67Transient drug-induced abolition of BAEPs in coma. ( Artru, F; Bertrand, O; García-Larrea, L; Mauguière, F; Pernier, J, 1988)
"The latency to convulsion and survival rate were significantly longer and higher, respectively, in the brain-injured group than in the sham-operated one."1.30Prior brain injury protects death from local anaesthetic-induced convulsion. ( Baba, H; Endoh, H; Fukuda, S; Kumagai, Y; Sato, K; Shimoji, K; Taga, K; Yamakura, T, 1997)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's4 (25.00)18.2507
2000's3 (18.75)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-López, A1
López-Alonso, I1
Pickerodt, PA1
von Haefen, C1
Amado-Rodríguez, L1
Reimann, H1
Niendorf, T1
Kuebler, W1
Albaiceta, GM1
Francis, RCE1
Spies, CD1
Gala, PK1
Henretig, FM1
Alpern, ER1
Sampayo, EM1
Maggiolini, E1
Viaro, R1
Franchi, G1
Lin, CC2
Yu, JH1
Li, WC1
Weng, YM1
Chen, SY1
FRIEDMAN, E1
Bozeman, WP1
Idris, AH1
White, PF1
Schlobohm, RM1
Pitts, LH1
Lindauer, JM1
Muir, JK2
Lyeth, BG1
Hamm, RJ2
Ellis, EF3
Temple, MD1
Pike, BR1
Endoh, H1
Kumagai, Y1
Baba, H1
Yamakura, T1
Taga, K1
Sato, K1
Fukuda, S1
Shimoji, K1
Clancy, MJ1
Rotem, M1
Constantini, S1
Shir, Y1
Cotev, S1
Brand, HA1
Matsko, TA1
Avart, HN1
García-Larrea, L1
Artru, F1
Bertrand, O1
Pernier, J1
Mauguière, F1
Floyd, JB1

Trials

1 trial available for lidocaine and Acute Brain Injuries

ArticleYear
A randomized study of drugs for preventing increases in intracranial pressure during endotracheal suctioning.
    Anesthesiology, 1982, Volume: 57, Issue:3

    Topics: Brain Injuries; Fentanyl; Humans; Intracranial Pressure; Intubation, Intratracheal; Lidocaine; Rando

1982

Other Studies

15 other studies available for lidocaine and Acute Brain Injuries

ArticleYear
Lung Purinoceptor Activation Triggers Ventilator-Induced Brain Injury.
    Critical care medicine, 2019, Volume: 47, Issue:11

    Topics: Anesthetics, Local; Animals; Brain Injuries; Cell Line; Disease Models, Animal; Hippocampus; Humans;

2019
An interesting case of a unilaterally dilated pupil.
    Pediatric emergency care, 2013, Volume: 29, Issue:5

    Topics: Anesthetics, Local; Anisocoria; Brain Injuries; Child, Preschool; Diagnosis, Differential; Epinephri

2013
Suppression of activity in the forelimb motor cortex temporarily enlarges forelimb representation in the homotopic cortex in adult rats.
    The European journal of neuroscience, 2008, Volume: 27, Issue:10

    Topics: Action Potentials; Anesthetics, Local; Animals; Brain Injuries; Brain Mapping; Denervation; Dominanc

2008
Postintubation hemodynamic effects of intravenous lidocaine in severe traumatic brain injury.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:9

    Topics: Anesthesia, General; Blood Pressure; Brain Injuries; Emergency Service, Hospital; Female; Heart Rate

2012
Chronic postconcussion syndrome.
    Medical trial technique quarterly, 1962, Volume: 8

    Topics: Brain; Brain Injuries; Lidocaine; Neurologic Manifestations; Post-Concussion Syndrome; Procaine; Ver

1962
Intracranial pressure changes during rapid sequence intubation: a swine model.
    The Journal of trauma, 2005, Volume: 58, Issue:2

    Topics: Animals; Brain Injuries; Cross-Over Studies; Disease Models, Animal; Emergency Treatment; Intracrani

2005
The effect of acute cocaine or lidocaine on behavioral function following fluid percussion brain injury in rats.
    Journal of neurotrauma, 1995, Volume: 12, Issue:1

    Topics: Animals; Behavior, Animal; Body Weight; Brain Injuries; Cocaine; Lidocaine; Male; Maze Learning; Mot

1995
Acute cocaine administration alters posttraumatic blood pressure and cerebral blood flow in rats.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Animals; Blood Pressure; Brain Injuries; Carbon Dioxide; Cerebrovascular Circulation; Cocaine; Hydro

1995
The effect of postinjury administration of polyethylene glycol-conjugated superoxide dismutase (pegorgotein, Dismutec) or lidocaine on behavioral function following fluid-percussion brain injury in rats.
    Journal of neurotrauma, 1996, Volume: 13, Issue:6

    Topics: Anesthetics, Local; Animals; Antioxidants; Behavior, Animal; Body Weight; Brain Injuries; Lidocaine;

1996
Prior brain injury protects death from local anaesthetic-induced convulsion.
    Brain research, 1997, Aug-29, Volume: 767, Issue:1

    Topics: Anesthetics, Local; Animals; Brain Injuries; Lidocaine; Male; Mice; Reaction Time; Seizures; Surviva

1997
A new way of demonstrating how close the evidence is to the question you asked.
    Emergency medicine journal : EMJ, 2001, Volume: 18, Issue:6

    Topics: Brain Injuries; Evidence-Based Medicine; Humans; Lidocaine; Treatment Outcome

2001
Life-threatening torsade de pointes arrhythmia associated with head injury.
    Neurosurgery, 1988, Volume: 23, Issue:1

    Topics: Aged; Brain Injuries; Cerebral Hemorrhage; Heart Ventricles; Hematoma; Humans; Lidocaine; Male; Tach

1988
Speech prosthesis retention problems in dysarthria: case report.
    Archives of physical medicine and rehabilitation, 1988, Volume: 69, Issue:3 Pt 1

    Topics: Adaptation, Physiological; Administration, Topical; Adult; Anesthesia, Local; Brain Injuries; Dysart

1988
Transient drug-induced abolition of BAEPs in coma.
    Neurology, 1988, Volume: 38, Issue:9

    Topics: Adult; Brain Injuries; Brain Stem; Coma; Drug Combinations; Evoked Potentials, Auditory; Female; Hum

1988
Traumatic cerebral edema relieved by stellate ganglion anesthesia.
    Southern medical journal, 1987, Volume: 80, Issue:10

    Topics: Adolescent; Autonomic Nerve Block; Brain Edema; Brain Injuries; Ganglia, Sympathetic; Humans; Lidoca

1987