Page last updated: 2024-10-28

lidocaine and Active Hyperemia

lidocaine has been researched along with Active Hyperemia in 18 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"The goal of this study was to evaluate the effect of different methods of tourniquet application and lidocaine administration on MP injection pain."9.17Reducing the pain of microemulsion propofol injections: a double-blind, randomized study of three methods of tourniquet and lidocaine. ( Kim, HZ; Kim, K; Kim, NS; Kong, MH; Lee, DK; Lee, IO; Lim, BG; Sung Kim, Y, 2013)
" Endoluminal SP caused mucosal hyperemia in the perfused jejunal segment that was not blocked by preperfusion of the segment with lidocaine (2% or 4%) or tetrodotoxin (3 X 10(-7) M)."7.66Endoluminal substance P as a cause of mucosal hyperemia in the feline gut by a nonneural mechanism. ( Gronstad, KO; Jaffe, BM; Yeo, CJ; Zinner, MJ, 1983)
"The goal of this study was to evaluate the effect of different methods of tourniquet application and lidocaine administration on MP injection pain."5.17Reducing the pain of microemulsion propofol injections: a double-blind, randomized study of three methods of tourniquet and lidocaine. ( Kim, HZ; Kim, K; Kim, NS; Kong, MH; Lee, DK; Lee, IO; Lim, BG; Sung Kim, Y, 2013)
"The capsaicin-sensitive afferent nerves mediate in part the HCl-induced mesenteric hyperemia."3.68Primary sensory nerves mediate in part the protective mesenteric hyperemia after intraduodenal acidification in rats. ( Leung, FW, 1993)
" Endoluminal SP caused mucosal hyperemia in the perfused jejunal segment that was not blocked by preperfusion of the segment with lidocaine (2% or 4%) or tetrodotoxin (3 X 10(-7) M)."3.66Endoluminal substance P as a cause of mucosal hyperemia in the feline gut by a nonneural mechanism. ( Gronstad, KO; Jaffe, BM; Yeo, CJ; Zinner, MJ, 1983)
"Induction of post-occlusive reactive hyperemia in malignant tumors is therefore a novel investigational approach that could lead to a new adjuvant tool to increase the efficacy of chemotherapy and radiotherapy, respectively through the synchronized temporary increase of tumor perfusion and oxygenation."2.77Post-occlusive reactive hyperemia in basal cell carcinoma and its potential application to improve the efficacy of solid tumor therapies. ( Fourme, E; Guihard, T; Le Masurier, P; Lebas, N; Reyal, J; Vilmer, C, 2012)
"Hyperemia was elicited in the anesthetized rat anterior mesenteric artery after cessation of intravenous norepinephrine infusion at 0."1.29Multifactorial mediation of post norepinephrine induced intestinal hyperemia. ( Hottenstein, OD; Jacobson, ED; Remak, G, 1994)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's4 (22.22)18.2507
2000's4 (22.22)29.6817
2010's6 (33.33)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Turner, CG1
Walker, DC1
Wong, BJ1
Kim, K1
Sung Kim, Y1
Lee, DK1
Lim, BG1
Kim, HZ1
Kong, MH1
Kim, NS1
Lee, IO1
Wiles, MD2
Dickson, E1
Moppett, IK2
Chatziralli, IP1
Papazisis, L1
Sergentanis, TN1
Dobson, SA1
Wilkins, BW1
Reyal, J1
Lebas, N1
Fourme, E1
Guihard, T1
Vilmer, C1
Le Masurier, P1
Cracowski, JL3
Gaillard-Bigot, F1
Cracowski, C1
Sors, C1
Roustit, M2
Millet, C1
Lorenzo, S2
Minson, CT2
Simmons, GH1
Carpentier, P1
Zinner, MJ1
Yeo, CJ1
Gronstad, KO1
Jaffe, BM1
Bühler-Singer, S1
Hiller, D1
Boateng, B1
Albrecht, HP1
Seidel, C1
Hornstein, OP1
Remak, G1
Hottenstein, OD1
Jacobson, ED1
Leung, FW1
Zochodne, DW1
Ho, LT1
Treister, G1
Bárány, EH1
Lokken, P1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Identification of Transient Receptor Potential (TRP) Channels as New Potential Therapeutic Targets in Primary and Secondary Raynaud's Phenomenon.[NCT03211325]29 participants (Actual)Interventional2016-10-18Completed
Etude peropératoire de la Perfusion Sanguine Des Carcinomes Basocellulaires Par Imageur Laser Doppler, au Cours de la Manipulation de l'Influx artériel Tumoral - Recherche d'un phénomène d'hyperémie Tumorale Post-occlusive[NCT01455363]12 participants (Actual)Interventional2011-06-30Completed
The Effect Of A Neurodynamic Treatment On Nerve Conduction In Clients With Low Back Pain[NCT01402895]9 participants (Actual)Interventional2011-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

7 trials available for lidocaine and Active Hyperemia

ArticleYear
Reducing the pain of microemulsion propofol injections: a double-blind, randomized study of three methods of tourniquet and lidocaine.
    Clinical therapeutics, 2013, Volume: 35, Issue:11

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female;

2013
Transient hyperaemic response to assess vascular reactivity of skin: effect of topical anaesthesia.
    British journal of anaesthesia, 2008, Volume: 101, Issue:3

    Topics: Adult; Anesthetics, Local; Blood Flow Velocity; Forearm; Humans; Hyperemia; Laser-Doppler Flowmetry;

2008
Lidocaine 2% jelly versus lidocaine 2%-sodium hyaluronate 0.3% drops in phacoemulsification surgery.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2010, Volume: 248, Issue:1

    Topics: Anesthetics, Local; Conjunctival Diseases; Drug Combinations; Humans; Hyaluronic Acid; Hyperemia; Le

2010
The effect of a new topical local anaesthetic delivery system on forearm skin blood flow reactivity.
    Anaesthesia, 2010, Volume: 65, Issue:2

    Topics: Administration, Cutaneous; Adult; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Band

2010
Post-occlusive reactive hyperemia in basal cell carcinoma and its potential application to improve the efficacy of solid tumor therapies.
    The Tohoku journal of experimental medicine, 2012, Volume: 227, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia; Carcinoma, Basal Cell; Female; Health; Humans; Hyperemia

2012
Involvement of cytochrome epoxygenase metabolites in cutaneous postocclusive hyperemia in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Jan-15, Volume: 114, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Adult; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Female;

2013
Effects of local anaesthesia on subdermal needle insertion pain and subsequent tests of microvascular function in human.
    European journal of pharmacology, 2007, Mar-22, Volume: 559, Issue:2-3

    Topics: Administration, Topical; Adult; Anesthetics, Combined; Anesthetics, Local; Blood Flow Velocity; Dose

2007

Other Studies

11 other studies available for lidocaine and Active Hyperemia

ArticleYear
Contribution of sensory nerves to cutaneous reactive hyperaemia in non-Hispanic Black and White young adults.
    Experimental physiology, 2023, Volume: 108, Issue:6

    Topics: Black or African American; Humans; Hyperemia; Lidocaine; Nitric Oxide; Regional Blood Flow; Sensory

2023
Bring on the heat: transient receptor potential vanilloid type-1 (TRPV-1) channels as a sensory link for local thermal hyperaemia.
    The Journal of physiology, 2010, Nov-01, Volume: 588, Issue:Pt 21

    Topics: Anesthetics, Local; Capsaicin; Hot Temperature; Humans; Hyperemia; Lidocaine; Lidocaine, Prilocaine

2010
Human cutaneous reactive hyperaemia: role of BKCa channels and sensory nerves.
    The Journal of physiology, 2007, Nov-15, Volume: 585, Issue:Pt 1

    Topics: Adult; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Hyperemia; Ketorolac; Large-Con

2007
Abnormal digital neurovascular response to local heating in systemic sclerosis.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Axons; Female; Fingers; Forearm; Hot Temperature; Human

2008
Endoluminal substance P as a cause of mucosal hyperemia in the feline gut by a nonneural mechanism.
    Surgery, 1983, Volume: 94, Issue:2

    Topics: Animals; Cats; Hyperemia; Intestinal Mucosa; Jejunum; Lidocaine; Male; Microspheres; Perfusion; Peri

1983
[Disordered cutaneous microcirculation in diabetic neuropathic foot ulcer. Is modification by retrograde transvenous perfusion therapy possible?].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1995, Volume: 46, Issue:6

    Topics: Adult; Aged; Blood Flow Velocity; Chemotherapy, Cancer, Regional Perfusion; Dexamethasone; Diabetic

1995
Multifactorial mediation of post norepinephrine induced intestinal hyperemia.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1994, Volume: 45, Issue:2

    Topics: Adenosine Deaminase; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists

1994
Primary sensory nerves mediate in part the protective mesenteric hyperemia after intraduodenal acidification in rats.
    Gastroenterology, 1993, Volume: 105, Issue:6

    Topics: Animals; Capsaicin; Duodenum; Hydrochloric Acid; Hyperemia; Lidocaine; Male; Mesenteric Artery, Supe

1993
Stimulation-induced peripheral nerve hyperemia: mediation by fibers innervating vasa nervorum?
    Brain research, 1991, Apr-12, Volume: 546, Issue:1

    Topics: Acidosis; Animals; Blood Gas Analysis; Blood Vessels; Electric Stimulation; Hydrogen-Ion Concentrati

1991
Degeneration mydriasis and hyperemia of the iris after superior cervical ganglionectomy in the rabbit. Evidence for release of more than norepinephrine during degeneration of adrenergic terminals.
    Investigative ophthalmology, 1970, Volume: 9, Issue:11

    Topics: Accommodation, Ocular; Adrenergic alpha-Antagonists; Animals; Atropine; Bretylium Compounds; Chlorpr

1970
[Local anesthetics and their pharmacology].
    Den Norske tannlaegeforenings tidende, 1968, Volume: 78, Issue:10

    Topics: Action Potentials; Anesthetics, Local; Chemistry, Pharmaceutical; Hyperemia; Hypersensitivity; Injec

1968