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lidocaine and Acidosis, Respiratory

lidocaine has been researched along with Acidosis, Respiratory in 10 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Acidosis, Respiratory: Respiratory retention of carbon dioxide. It may be chronic or acute.

Research Excerpts

ExcerptRelevanceReference
"To test the hypothesis that acidosis can increase the toxicity of bupivacaine more than that of lidocaine by increasing the distribution into the brain, myocardium, or both, studies were performed to measure the in vivo tissue:blood partition coefficients during continuous steady state intravenous infusions of these agents in anesthetized sheep during normal acid-base status and during combined respiratory-metabolic acidosis."7.67The influence of acidosis on the distribution of lidocaine and bupivacaine into the myocardium and brain of the sheep. ( Mather, LE; Nancarrow, C; Plummer, JL; Runciman, WB; Upton, RN, 1987)
"To test the hypothesis that acidosis can increase the toxicity of bupivacaine more than that of lidocaine by increasing the distribution into the brain, myocardium, or both, studies were performed to measure the in vivo tissue:blood partition coefficients during continuous steady state intravenous infusions of these agents in anesthetized sheep during normal acid-base status and during combined respiratory-metabolic acidosis."3.67The influence of acidosis on the distribution of lidocaine and bupivacaine into the myocardium and brain of the sheep. ( Mather, LE; Nancarrow, C; Plummer, JL; Runciman, WB; Upton, RN, 1987)
"Lidocaine was infused in 4 different doses: 2 mg."1.29[Effect of intravenous lidocaine infusion on arterial baroreflex]. ( Yoneda, I, 1993)
"The conclusion of this study was that a respiratory acidosis increased the central nervous system toxicity of local anaesthetics and that the underlying metabolic conditions modified this increase."1.25Central nervous system effects of local anaesthetic agents. ( Englesson, S; Matousek, M, 1975)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BENDIXEN, HH1
LAVER, MB1
FLACKE, WE1
Yoneda, I1
Englesson, S1
Matousek, M1
Moore, EN1
Spear, JF1
Nancarrow, C1
Runciman, WB1
Mather, LE1
Upton, RN1
Plummer, JL1
Rosen, MA1
Thigpen, JW1
Shnider, SM1
Foutz, SE1
Levinson, G1
Koike, M1
Katz, RL1
Bigger, JT1
Crawford, JS1
Mckenna, G1
Engle, RP1
Brooks, H1
Dalen, J1
Fox, GS1
Houle, GL1

Reviews

1 review available for lidocaine and Acidosis, Respiratory

ArticleYear
Cardiac arrhythmias during anesthesia and operation.
    Anesthesiology, 1970, Volume: 33, Issue:2

    Topics: Acidosis, Respiratory; Age Factors; Anesthesia; Anesthetics; Animals; Arrhythmia, Sinus; Arrhythmias

1970

Other Studies

9 other studies available for lidocaine and Acidosis, Respiratory

ArticleYear
INFLUENCE OF RESPIRATORY ACIDOSIS ON CIRCULATORY EFFECT OF EPINEPHRINE IN DOGS.
    Circulation research, 1963, Volume: 13

    Topics: Acidosis; Acidosis, Respiratory; Animals; Atropine; Blood Circulation; Blood Pressure; Carbon Dioxid

1963
[Effect of intravenous lidocaine infusion on arterial baroreflex].
    Masui. The Japanese journal of anesthesiology, 1993, Volume: 42, Issue:5

    Topics: Acidosis, Respiratory; Animals; Dogs; Infusions, Intravenous; Lidocaine; Pressoreceptors; Reflex

1993
Central nervous system effects of local anaesthetic agents.
    British journal of anaesthesia, 1975, Volume: 47 suppl

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Allyl Compounds; Amines; Anesthetics, Local; Anilides;

1975
Ventricular fibrillation threshold; its physiological and pharmacological importance.
    Archives of internal medicine, 1975, Volume: 135, Issue:3

    Topics: Acidosis, Respiratory; Action Potentials; Aminophylline; Animals; Digitalis Glycosides; Dogs; Electr

1975
The influence of acidosis on the distribution of lidocaine and bupivacaine into the myocardium and brain of the sheep.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:10

    Topics: Acidosis; Acidosis, Respiratory; Animals; Brain; Bupivacaine; Female; Hydrogen-Ion Concentration; Li

1987
Bupivacaine-induced cardiotoxicity in hypoxic and acidotic sheep.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:11

    Topics: Acidosis, Respiratory; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Dose-Response Rel

1985
The anaesthetist's contribution to maternal mortality.
    British journal of anaesthesia, 1970, Volume: 42, Issue:1

    Topics: Acidosis, Respiratory; Anesthesia, Obstetrical; Cesarean Section; Diet; Female; Gastroesophageal Ref

1970
Cardiac arrhythmias during electroshock therapy: significance, prevention, and treatment.
    The American journal of psychiatry, 1970, Volume: 127, Issue:4

    Topics: Acidosis, Respiratory; Aged; Arrhythmias, Cardiac; Blood Gas Analysis; Coronary Disease; Electrocard

1970
Acid-base studies in elective caesarean sections during epidural and general anaesthesia.
    Canadian Anaesthetists' Society journal, 1971, Volume: 18, Issue:1

    Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Anesthesia, Inhalation; Anesthesia, Obstetri

1971