lidocaine has been researched along with Ache in 2407 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the incidence of pain upon injection of 1% propofol (Propofol-Lipuro 1%, B." | 10.21 | [Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides]. ( Ayuso, MA; Fernández, J; Gomar, C; Luis, M; Sala, X, 2004) |
| "Children who received lidocaine-prilocaine emulsion reported less pain (mean FPS score = 1." | 10.17 | Age-related response to lidocaine-prilocaine (EMLA) emulsion and effect of music distraction on the pain of intravenous cannulation. ( Abu-Saad, HH; Arts, SE; Champion, GD; Crawford, MR; Fisher, RJ; Juniper, KH; Ziegler, JB, 1994) |
| "Since one of the nurse's duties is to employ different methods to reduce pain caused by treatment procedures, this study was conducted to determine the effect of lidocaine spray and ice spray on pain intensity at the muscle injection site." | 9.69 | Comparative Study of the Effect of Lidocaine Spray and Ice Spray on the Pain Intensity During Intramuscular Injection: A Randomized Clinical Trial. ( Bordbar, R; Hasheminik, M; Jamalinik, M; Khaleghipour, M; Khorashadizadeh, F; Lakziyan, R; Paivar, B; Shafigh, N; Siavoshi, M, 2023) |
| "To compare effectiveness of ice pack to topical lidocaine-prilocaine for pain reduction during axillary laser hair removal." | 9.69 | Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial. ( Alam, M; Anvery, N; Brieva, JC; Christensen, RE; Dirr, MA; Geisler, A; Roongpisuthipong, W; Schaeffer, M; Waldman, A, 2023) |
| "The aim of this prospective, double-blind, randomized controlled trial was to compare the effect of oral premedication of meloxicam, ketorolac, dexamethasone, ibuprofen, or placebo on the success of inferior alveolar nerve blocks (IANB) of mandibular posterior teeth in patients experiencing symptomatic irreversible pulpitis." | 9.69 | Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial. ( Elnaghy, AM; Elsaka, SE; Elshazli, AH, 2023) |
| "Compound lidocaine/prilocaine cream combined with tetracaine may be a more effective approach for preventing coughing and stabilising circulation during extubation following general anaesthesia." | 9.69 | Compound lidocaine/prilocaine cream combined with tetracaine prevents cough caused by extubation after general anaesthesia: a randomised controlled trial. ( Gao, J; Li, T; Li, Y; Wang, M; Zhang, E; Zhang, H; Zhang, L; Zhao, X, 2023) |
| "This study aimed to compare the effects of cooling and lidocaine sprays on needle insertion pain in hemodialysis patients." | 9.69 | Cooling spray or lidocaine spray and needle insertion pain in hemodialysis patients: an open-label cross-over randomized clinical trial. ( Armat, MR; Eshghi, M; Hejazi, S; Hoseini Azizi, T; Kameli, A; Khosravi Pour, A, 2023) |
| " Pain scores were reduced at 1 hour for the lidocaine (OR 4." | 9.69 | Topical Lidocaine or Lidocaine/Diltiazem Ointment Following Rubber Band Ligation of Hemorrhoids: A Prospective 3-Armed Randomized Controlled Trial. ( Carroll, R; Draganic, B; Kwok, AMF; Leigh, L; Smith, SR; Zhao, J, 2023) |
| "No study has assessed the effects of the incorporation of isolated lidocaine into botulinum toxin for reducing its pain or complications." | 9.69 | Effects of lidocaine incorporation (without epinephrine) on pain and 2-week complications of botulinum toxin: a double-blind randomized placebo-controlled clinical trial. ( Bagheri, D; Fateh, A; Kahali, R; Rakhshan, V; Sarkarat, F, 2023) |
| "Analgesia, Fentanyl, Lidocaine spray, Pain, Rib fracture, Tramadol." | 9.69 | Comparison of the Analgesic Efficacy of Lidocaine Spray versus Tramadol and Fentanyl for Pain Control in Rib Fractures. ( Donmez, S; Erdem, AB; Sener, A, 2023) |
| "Regardless of the positive attributes of propofol, it is frequently associated with pain on injection." | 9.69 | Prevention of pain on injection of propofol using ice gel pack versus pre-treatment with lignocaine: a randomized controlled trial. ( Chauhan, R; Karki, Y; Luthra, A; Meena, SC; Sarna, R; Singh, N; Thappa, P, 2023) |
| "The local use of lidocaine spray in patients with TIVAP is effective, acceptable, and safe to alleviate the pain caused by non-coring needle puncture." | 9.69 | Effect of lidocaine spray on reliving non-coring needle puncture-related pain in patients with totally implantable venous access port: a randomized controlled trial. ( Chang, J; Niu, S; Ye, L; Zhang, H; Zhang, Y; Zhu, Y, 2023) |
| "The use of an endotracheal tube (ET) cuff filled with alkalized lidocaine (AL) can suppress ET-induced emergence phenomena, such as hypertension, tachycardia and coughing, and postoperative sore throat (POST) and hoarseness (PH)." | 9.69 | Alkalized lidocaine in a tapered cuff suppresses endotracheal tube-induced hemodynamic changes: a randomized controlled trial. ( Ishida, K; Ito, M; Kawamata, M; Maruyama, Y; Shen, D; Tanaka, S; Yoshiyama, Y, 2023) |
| "Intravertebral injections of lidocaine during PKP can successfully reduce intraoperative pain." | 9.69 | Intraoperative analgesic effect of intravertebral lidocaine injection during percutaneous kyphoplasty in the treatment of thoracolumbar compression fractures in elderly patients. ( Chang, X; Liu, J; Wang, J; Yan, H; Yin, J; Zhang, Y; Zhao, X, 2023) |
| "To investigate the possible advantage of topical lidocaine and intravenous midazolam in preventing spasm and pain related to the radial artery." | 9.69 | Topical Lidocaine And Or/ Intravenous Midazolam Before Radial Coronary Angiography To Prevent Radial Artery Spasm. ( Elattar, MM; Haseeb, WA; NBiomy, R; Salama, MK, 2023) |
| "The analgesic efficacy of lidocaine 10% spray, etofenamate spray, and placebo spray used together with standard dexketoprofen 50 mg intravenous treatment in the pain management of rib fractures were similar to each other and although there was a difference at the 120th min, this difference was not statistically significant." | 9.69 | Placebo-controlled randomized double-blind comparison of the analgesic efficacy of lidocaine spray and etofenamate spray in pain control of rib fractures. ( Altas, F; Dönmez, S; Erdem, AB; Mutlu, Rİ; Şener, A, 2023) |
| "In women who underwent breast surgery, IV lidocaine bolus administered just before extubation attenuated bucking, cough and sore throat, and PONV for 24 hours after general anesthesia, without prolonging the emergence." | 9.69 | Effects of an intravenous lidocaine bolus before tracheal extubation on recovery after breast surgery - Lidocaine at the End (LATE) study: a randomized controlled clinical trial. ( Mraovic, B; Šimurina, T, 2023) |
| "We tested the following hypothesis: The addition of intranasal fentanyl to the standard practice of local infiltration with lidocaine would provide better pain control than lidocaine alone for adult ED patients undergoing I&D." | 9.51 | A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess. ( Baer, J; Feliciano, C; Friedman, BW; Gupta, C; Latev, A; Sharpe, S, 2022) |
| "Successful anesthesia (defined as no or mild pain during any of steps and no need for additional injection) is obtained in 12% of patients in the lidocaine group, while DEX-lidocaine group increased the success rate of IANB to 72% (p-value = 0." | 9.51 | Efficacy of adding dexmedetomidine to lidocaine to enhance inferior alveolar nerve block in patients with asymptomatic irreversible pulpitis: double-blind randomized clinical trial. ( Moshari, A; Moshari, M; Vahedi, Z, 2022) |
| "This randomized study suggests that topical 1% lidocaine ear drops with paracetamol or ibuprofen seems to provide effective and rapid relief for children presenting with ear pain attributed to AOM." | 9.51 | The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media. ( Alabaz, D; Albayrak, E; Bedir, T; Bozdemir, ŞE; Büyükcam, A; Çelebi, S; Çiftçi, E; İlarslan, EÇ; Kara, A; Kara, M; Kara, SS; Kara, TT; Karakaşlılar, S; Karbuz, A; Kaya, C; Öz, FN; Özdemir, H; Sali, E; Somer, A; Sönmez, G; Sütçü, M; Tezer, H, 2022) |
| "The primary outcome was the efficacy of ondansetron compared to lidocaine and placebo for the reduction of propofol injection pain." | 9.51 | A comparison of ondansetron and lidocaine in reducing injection pain of propofol: a randomized controlled study. ( Chaofan, S; Kosem, R; Plansangkate, P; Tanasansuttiporn, J; Termthong, S; Wasinwong, W, 2022) |
| "In this study, we aimed to evaluate the effect of administering lidocaine as a local anesthetic at the puncture site prior cannulation on reduction of pain during intravenous cannulation (IVC)." | 9.51 | Padded Dressing with Lidocaine HCL for Reducing Pain during Intravenous Cannulation in Adult Patients: A Randomized Controlled Clinical Trial. ( Kartufan, FF, 2022) |
| "The aim of this study was to assess inferior alveolar nerve block (IANB) success of 2% mepivacaine (Scandonest 2%, Septodont, France) and 4% articaine (Septanest 4%, Septodont) in patients with symptomatic irreversible pulpitis (SIP) in mandibular molars during access cavity preparation and instrumentation." | 9.51 | Inferior alveolar nerve block success of 2% mepivacaine versus 4% articaine in patients with symptomatic irreversible pulpitis in mandibular molars: A randomized double-blind single-centre clinical trial. ( Amin, SAW; Bedier, MM; El Boghdadi, RM; Ezzat, K; Fouda, MY; Gawdat, SI; Habib, MFOM; Marzouk, A; Tarek, S; Teama, SME, 2022) |
| " Adult patients who presented with the complaint of pain after a scorpion sting and did not have systemic findings were randomly assigned to 1 of the following 4 groups: IV paracetamol, IV dexketoprofen trometamol, topical lidocaine, and placebo." | 9.51 | Comparison of Intravenous Paracetamol, Dexketoprofen Trometamol, or Topical Lidocaine Use for Pain Relief in Scorpion Stings: A Placebo-Controlled, Randomized Study. ( Aktaş, N; Arslan, E; Aydın, İ; Gülaçtı, U; Sönmez, C; Turgut, K; Yavuz, E, 2022) |
| "To compare the effect of intra-cuff lidocaine versus alkalinized lidocaine in the prevention of post-operative sore throat." | 9.51 | Comparison of intra-cuff lidocaine vs alkalinized lidocaine effects for prevention of post-operative sore throat. ( Abbas, N; Asghar, A; Hassan, SU; Naqvi, N; Rafique, M; Tariq, S, 2022) |
| "The objective of this study was to assess the efficacy of lidocaine 4% cream as pain management during immunizations and to evaluate satisfaction of caregivers and nursing staff." | 9.51 | Use of Lidocaine Cream for Pain Management During Immunizations of Infants at an Urban Health Clinic. ( Alshehry, AO; Fischetti, B; Lepa, T; Morgan, EP; Sessa, K; Valentine, M, 2022) |
| "Lidocaine/tetracaine 7%/7% peel cream (L/T-pC) is very effective in reducing pain in several dermatological procedures, such as hair or tattoo laser removal or conventional photodynamic therapy associated pain." | 9.51 | Assessment of clinical efficacy of lidocaine/tetracaine 7%/7% peel cream in fractional microablative laser procedure-associated pain for facial skin aging treatment. A randomized, controlled, single-blind trial. ( Caprari, E; Milani, M; Viciguerra, MT, 2022) |
| "To determine whether the addition of inhaled methoxyflurane to periprostatic infiltration of local anaesthetic (PILA) during transrectal ultrasonography-guided prostate biopsies (TRUSBs) improved pain and other aspects of the experience." | 9.51 | 'Pain-free TRUS B': a phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography-guided prostate biopsy (ANZUP 1501). ( Buchan, N; Chalasani, V; Davis, ID; Espinoza, D; Ford, KS; Frydenberg, M; Gilling, P; Gordon, B; Grummet, J; Hawks, C; Hayne, D; Konstantatos, A; Martin, AJ; McCombie, SP; Nixon, A; O'Brien, C; Patel, MI; Sengupta, S; Shahbaz, S; Stockler, MR; Subramaniam, S; Williams, S; Woo, HH, 2022) |
| "Propofol-induced injection pain (PIP) is a well-known problem in general anesthesia." | 9.41 | Efficacy of Pre-Treatment with Remimazolam on Prevention of Propofol-Induced Injection Pain in Patients Undergoing Abortion or Curettage: A Prospective, Double-Blinded, Randomized and Placebo-Controlled Clinical Trial. ( Cao, H; Gong, X; Guan, X; Huang, X; Jiao, Z; Lan, H; Lin, C; Liu, S; Tan, Y; Xu, B, 2021) |
| "To compare the effectiveness of suppository diclofenac (100mg), cervical lidocaine 25mg -prilocaine 25mg cream (5% EMLA) and placebo in pain relief for hysterosalpingography." | 9.41 | Pain Relief for Hysterosalpingography: A Randomized Controlled, Double Blinded Trial Comparing Suppository Diclofenac, Prilocaine/Lignocaine (EMLA) Cream And Placebo. ( Agboghoroma, OC; Babandi, RM; Durojaiye, KW; Essiet, EA; Jimoh, KO, 2021) |
| "10% lidocaine spray was found to be an effective local anaesthetic method for reducing pain during insertion of Cu-IUD." | 9.41 | 10% lidocaine spray for pain control during intrauterine device insertion: a randomised, double-blind, placebo-controlled trial. ( Mongkornthong, T; Panichyawat, N; Sirimai, K; Wongwananuruk, T, 2021) |
| "To determine the median effective dose (ED50) of prophylactic intravenous lidocaine for the prevention of propofol medium-chain triglyceride/long-chain triglyceride (MCT/LCT) emulsion injection pain." | 9.41 | Median Effective Dose of Lidocaine for the Prevention of Pain Caused by the Injection of Propofol Formulated with Medium- and Long-Chain Triglycerides Based on Lean Body Weight. ( Ma, R; Shan, Q; Sui, W; Tan, C; Tian, S; Xing, Z; Zhang, D; Zhang, Z; Zhou, W, 2021) |
| "Lidocaine coinfusion could effectively alleviate vascular pain induced by hypertonic saline infusion." | 9.41 | Lidocaine coinfusion alleviates vascular pain induced by hypertonic saline infusion: a randomized, placebo-controlled trial. ( Chen, S; Liao, Z; Shi, X; Song, Z; Zhang, Y; Zhao, N, 2021) |
| "In recent years, lidocaine infusion for pain management during long operations is becoming more widespread in anesthesiology practice." | 9.41 | Does intravenous lidocaine added to nonsteroidal anti-inflammatory drugs reduce pain during colposcopy? A prospective randomized double-blind study. ( Ates, I; Aydin, ME; Oral Ahiskalioglu, E; Topdagi Yilmaz, EP; Topdaği, YE, 2021) |
| " Lidocaine given intravenously has been shown in two small, uncontrolled studies to have an appreciable effect on pain after burns." | 9.34 | Lidocaine infusion has a 25% opioid-sparing effect on background pain after burns: A prospective, randomised, double-blind, controlled trial. ( Abdelrahman, I; Elmasry, M; Sjoberg, F; Steinvall, I, 2020) |
| " The objective of the current study was to evaluate the effectiveness of topical lidocaine in relieving pain related to INM administration." | 9.34 | The effectiveness of topical lidocaine in relieving pain related to intranasal midazolam sedation: a randomized, placebo-controlled clinical trial. ( Khalil, W; Raslan, N, 2020) |
| "The 3P-trial has demonstrated that the preventive application of the self-occlusive lidocaine 7%-tetracaine 7% cream is very effective in reducing the procedure-associated pain during MAL-cPDT for the treatment of AK lesions." | 9.34 | Efficacy of lidocaine 7 %, tetracaine 7 % self-occlusive cream in reducing MAL-cPDT-associated pain in subjects with actinic keratosis: A randomized, single-blind, vehicle-controlled trial (The "3P-Trial"). ( Brumana, MB; Milani, M; Puviani, M, 2020) |
| "2% of subjects who were treated with HAF-Lidocaine reported reduced pain when compared with those who were treated with HAF and the mean VAS score difference was 38." | 9.34 | Reduced pain with injection of hyaluronic acid with pre-incorporated lidocaine for nasolabial fold correction: A multicenter, double-blind, randomized, active-controlled, split-face designed, clinical study. ( Choi, SY; Han, HS; Kim, BJ; Lee, JS; Lee, YW; Yoo, KH, 2020) |
| "Determine if low-dose lidocaine as a diluent during CIESI causes clinically meaningful (1) upper extremity weakness and (2) immediate pain relief when compared with saline." | 9.34 | Effect of low-dose lidocaine on objective upper extremity strength and immediate pain relief following cervical interlaminar epidural injections: a double-blinded randomized controlled trial. ( Bougie, D; Burnham, T; Cunningham, S; Kendall, RW; McCormick, ZL; Teramoto, M; Walega, DR, 2020) |
| "We compared the analgesic effects of intravenous (IV) lidocaine and IV morphine for the treatment of severe pain in the emergency department (ED)." | 9.30 | Intravenous Lidocaine Provides Similar Analgesia to Intravenous Morphine for Undifferentiated Severe Pain in the Emergency Department: A Pilot, Unblinded Randomized Controlled Trial. ( Clattenburg, EJ; Flores, S; Hailozian, C; Herring, AA; Louie, D; Nguyen, A; Yoo, T, 2019) |
| "To determine the effect of cold therapy, music therapy and lidocaine spray on pain and anxiety following chest tube removal (CTR)." | 9.30 | The use of cold therapy, music therapy and lidocaine spray for reducing pain and anxiety following chest tube removal. ( Aktaş, YY; Karabulut, N, 2019) |
| "To determine the analgesic efficacy and analgesic duration of lidocaine 20 mg and 40 mg on eliminating the vascular pain associated with hypertonic saline infusion." | 9.30 | The analgesic efficacy and duration of lidocaine on vascular pain induced by hypertonic saline infusion: a double-blinded, randomized control trial. ( Liu, Z; Song, Z; Zhang, Y, 2019) |
| "To evaluate the effect of doxepin mouthwash or diphenhydramine-lidocaine-antacid mouthwash for the treatment of oral mucositis-related pain." | 9.30 | Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial. ( Curtis, A; Ko, SJ; Le-Rademacher, JG; Leenstra, JL; Loprinzi, CL; Martenson, JA; Miller, RC; Novotny, PJ; Qin, R; Reiter, PL; Rine, G; Singh, AK; Sio, TT; Tan, AD, 2019) |
| "To compare the safety and efficacy of xylocaine gel and ketorolac as opioid-sparing analgesia compared with pethidine for shock wave lithotripsy (SWL) pain." | 9.30 | Efficacy of pethidine, ketorolac, and lidocaine gel as analgesics for pain control in shockwave lithotripsy: A single-blinded randomized controlled trial. ( Abol-Enein, H; Atwa, AM; El-Assmy, A; Elbaset, MA; Fadallah, M; Ghobrial, FK; Hashem, A; Laymon, M; Sheir, KZ, 2019) |
| "Lidocaine alleviates propofol injection pain." | 9.27 | Intravenous Lidocaine Alleviates the Pain of Propofol Injection by Local Anesthetic and Central Analgesic Effects. ( Cai, J; Hei, Z; Liang, L; Luo, C; Xing, J; Zhou, S, 2018) |
| "05 mol/L GABA, 1% lidocaine) was investigated for the amelioration of pain and sensitivity induced by application of capsaicin (1%, 2 min) to the tongue of thirty healthy male and female subjects in this four-session, randomized, placebo-controlled, double-blinded, cross-over study." | 9.27 | γ-Aminobutyric acid (GABA) oral rinse reduces capsaicin-induced burning mouth pain sensation: An experimental quantitative sensory testing study in healthy subjects. ( Arendt-Nielsen, L; Cairns, BE; Wang, K; Zhang, Y, 2018) |
| "Lidocaine is used to alleviate procedural pain but paradoxically increases pain during injection." | 9.27 | Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial. ( Doman, ER; Hall, JB; Kress, JP; Patel, BK; Patel, SB; Pohlman, AS; Wendlandt, BN; Wolfe, KS, 2018) |
| "Nociceptive thresholds and supra-threshold pain ratings as well as their reduction upon local injection with lidocaine were compared between healthy subjects and patients with erythromelalgia (EM)." | 9.24 | Pain thresholds, supra-threshold pain and lidocaine sensitivity in patients with erythromelalgia, including the I848Tmutation in Na ( Helås, T; Jönsson, B; Jørum, E; Kleggetveit, IP; Quiding, H; Sagafos, D; Salter, H; Schmelz, M; Segerdahl, M; Zhang, Z, 2017) |
| "Propofol causes injection pain." | 9.24 | Preventive effect of a vapocoolant spray on propofol-induced pain: a prospective, double-blind, randomized study. ( Kim, DH; Lee, MY; Moon, YE, 2017) |
| " The purpose of this study was to determine the influence of lidocaine temperature on pain during subcutaneous injection." | 9.24 | The influence of Lidocaine temperature on pain during subcutaneous injection. ( Ballo, S; Finsen, V; Foss, OA; Hjelseng, T; Lundbom, JS; Skarsvåg, TI; Tangen, LF; Wågø, KJ, 2017) |
| "The objective was to investigate the analgesic effect of cervical lidocaine-prilocaine (LP) cream in alleviating pain during copper T380A intrauterine device (IUD) insertion among parous women." | 9.24 | Effect of cervical lidocaine-prilocaine cream on pain perception during copper T380A intrauterine device insertion among parous women: A randomized double-blind controlled trial. ( Abbas, AM; Abdellah, MS; Abdellah, NH; Abdelmagied, AM; Ali, MK; Bahloul, M; Khalaf, M, 2017) |
| "To assess efficacy of two different techniques of lidocaine injection in the uterine arteries to reduce pain following uterine artery embolization (UAE) for leiomyomas." | 9.24 | Intraarterial Lidocaine for Pain Control in Uterine Artery Embolization: A Prospective, Randomized Study. ( Mironov, O; Noel-Lamy, M; Rajan, DK; Simons, ME; Sniderman, KW; Tan, KT, 2017) |
| "To study the benefit of applying topical anesthetics or a 1:1 mixture of 1% lidocaine and TA at the TA injection site to alleviate pain during keloid treatment." | 9.24 | A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial. ( Burusapat, C; Usanakornkul, A, 2017) |
| "Significant pain reduction during IUD insertion can be achieved by using 10% lidocaine spray alone." | 9.22 | Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial. ( Açmaz, G; Aksoy, H; Aksoy, Ü; Babayigit, M; Ozyurt, S, 2016) |
| "Administration of 300 mg MgSO4 plus 40 mg lidocaine reduces propofol injection pain very well." | 9.22 | Magnesium Sulfate Plus Lidocaine Reduces Propofol Injection Pain: A Double-blind, Randomized Study. ( Lin, W; Sun, J; Wang, W; Zhou, J; Zhou, R, 2016) |
| "To evaluate the efficacy of topical lidocaine 2% gel in reducing the pain associated with the insertion of nasal continuous positive airway pressure (nCPAP) prongs in preterm infants." | 9.22 | Does Topical Lidocaine Reduce the Pain Associated With the Insertion of Nasal Continuous Positive Airway Pressure Prongs in Preterm Infants?: A Randomized, Controlled Pilot Trial. ( Abdel-Hady, H; Elsharkawy, A; Soliman, H, 2016) |
| "Research on the safety and efficacy of continuous lidocaine infusions (CLIs) for the treatment of pain in the pediatric setting is limited." | 9.22 | Continuous Lidocaine Infusions to Manage Opioid-Refractory Pain in a Series of Cancer Patients in a Pediatric Hospital. ( Beckman, EJ; DeMonbrun, A; Gibbons, K; Hakel, S; Keefer, P; Liu, M; Niedner, M; Saul, D; Stewart, M; Wagner, D, 2016) |
| "To determine the effectiveness of diclofenac potassium combined with 2% lidocaine gel in reducing the pain of intrauterine device (IUD) insertion." | 9.22 | Diclofenac plus lidocaine gel for pain relief during intrauterine device insertion. A randomized, double-blinded, placebo-controlled study. ( Elsetohy, KA; Fouda, UM; Salah Eldin, NM; Shaban, MM; Sobh, SM; Tolba, HA, 2016) |
| "Premedication with 2 mg of IV midazolam reduces pain of NGT insertion in ED patients without the need for full procedural sedation." | 9.22 | Does Routine Midazolam Administration Prior to Nasogastric Tube Insertion in the Emergency Department Decrease Patients' Pain? (A Pilot Study). ( Buinewicz, JD; Freeman, K; Gutierrez, K; Manning, CT; O'Keefe, MF; Sewatsky, TP; Zgonis, E, 2016) |
| "The combination of 240 mg of intravenous lidocaine (once a week for 4 weeks) with 25 mg of amitriptyline for 8 weeks had no meaningful impact in fibromyalgia patients." | 9.22 | Effect of intravenous lidocaine combined with amitriptyline on pain intensity, clinical manifestations and the concentrations of IL-1, IL-6 and IL-8 in patients with fibromyalgia: A randomized double-blind study. ( Albertoni Giraldes, AL; Brunialti, MK; Leal, PD; Sakata, RK; Salomão, R, 2016) |
| "Lidocaine reduces pain that occurs upon the intravenous injection of propofol." | 9.22 | Comparison of the effects of lidocaine pre-administration and local warming of the intravenous access site on propofol injection pain: Randomized, double-blind controlled trial. ( Jeong, M; Yoon, H, 2016) |
| "To compare pain control at various time points during first-trimester surgical abortion using a patient-administered lidocaine gel compared with a traditional lidocaine paracervical block." | 9.22 | Self-Administered Lidocaine Gel for Pain Control With First-Trimester Surgical Abortion: A Randomized Controlled Trial. ( Blumenthal, PD; Conti, JA; Lerma, K; Shaw, KA, 2016) |
| "Although liposomal bupivacaine had some effect on soft tissue anesthesia, it did not reduce pain to manageable clinical levels in patients presenting with untreated, symptomatic irreversible pulpitis." | 9.22 | Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial. ( Beck, M; Bultema, K; Drum, M; Fowler, S; Nusstein, J; Reader, A, 2016) |
| "Pretreatment with oral pregabalin 150 mg and intravenous lidocaine 40 mg with venous occlusion equally reduced pain from propofol injection." | 9.22 | Comparative study between 2 different doses of pregabalin and lidocaine on pain following propofol injection: A double-blind, randomized clinical consort study. ( Choi, E; Jeon, Y; Kim, D, 2016) |
| "To compare the pain perception between intraurethral instillation of 2% lidocaine gel and liquid paraffin during Urodynamic study in men." | 9.20 | Liquid paraffin is superior to 2% lidocaine gel in reducing urethral pain during urodynamic study in men: A pilot study. ( Beberashvili, I; Sabler, IM; Siegel, YI; Stav, K; Taleb, E; Zisman, A, 2015) |
| "The incidence of propofol injection pain is high in children, but no methods have been found to suppress it completely." | 9.20 | Preemptive dexmedetomidine to prevent propofol injection pain in children. ( Dong, C; Lu, Y; Yu, J; Zhang, Y, 2015) |
| "In this double-blind, placebo-controlled, randomized trial, the combination of intravenous magnesium sulfate and lidocaine offered no additional benefit for the relief of propofol injection pain compared to intravenous lidocaine alone." | 9.20 | Magnesium sulfate with lidocaine for preventing propofol injection pain: a randomized, double-blind, placebo-controlled trial. ( Galgon, RE; Groth, J; Heier, J; Schroeder, KM; Strube, P; Wang, S, 2015) |
| "To compare the effectiveness of intravenous lidocaine and intravenous morphine in decreasing pain in patients with critical limb ischaemia." | 9.20 | Comparison of intravenous lidocaine versus morphine in alleviating pain in patients with critical limb ischaemia. ( Aghaie Meybodi, M; Saeedi, M; Shakoor, D; Vahidi, E, 2015) |
| " Significant reduction in pain intensity was observed with topical lidocaine group when compared with the ice application group (p < 0." | 9.20 | A randomized trial comparing intravenous paracetamol, topical lidocaine, and ice application for treatment of pain associated with scorpion stings. ( Aksel, G; Çorbacioğlu, ŞK; Doğan, NÖ; Güler, S, 2015) |
| "The purpose of this prospective, randomized, double-blind study was to compare the anesthetic efficacy of buffered with nonbuffered 2% lidocaine with 1:80,000 epinephrine solution for inferior alveolar nerve (IAN) block in patients with mandibular posterior teeth experiencing symptomatic irreversible pulpitis." | 9.20 | Effect of sodium bicarbonate-buffered lidocaine on the success of inferior alveolar nerve block for teeth with symptomatic irreversible pulpitis: a prospective, randomized double-blind study. ( Baghaei, B; Khademi, A; Noormohammadi, H; Saatchi, M, 2015) |
| " Pain relief was observed with lidocaine vs." | 9.20 | Novel topical formulation of lidocaine provides significant pain relief for intrauterine device insertion: pharmacokinetic evaluation and randomized placebo-controlled trial. ( Conner, P; Ekman-Ordeberg, G; Liliecreutz, C; Tingåker, BK; Tornblom-Paulander, S; Werner, A; Wessel, H, 2015) |
| "This study aims to analyze the efficiency of EMLA cream and ethyl chloride spray application for pain alleviation before botulinum toxin injection." | 9.20 | A Clinical Comparison of EMLA Cream and Ethyl Chloride Spray Application for Pain Relief of Forehead Botulinum Toxin Injection. ( Irkoren, S; Karaca, H; Ozkan, HS, 2015) |
| "Hyaluronic acid (HA) fillers are sometimes mixed with lidocaine to mitigate pain." | 9.20 | A blinded, randomized, split-face pilot study of bruising and pain with hyaluronic acid for correction of perioral lines using no lidocaine, lidocaine alone, and lidocaine and epinephrine. ( Howell, DJ; Moradi, A; Moradi-Poehler, J; Shirazi, A; Turner, J, 2015) |
| "To evaluate the efficacy of tramadol, lidocaine, and a combination of tramadol with lidocaine in pain relief using periprostatic nerve block technique by guidance of transrectal ultrasound (TRUS) before the prostate biopsy (PBx)." | 9.20 | Combination of Tramadol and Lidocaine for Pain Control During Transrectal Ultrasound-guided Prostate Biopsy: A Randomized Double-blinded Study. ( Bayrak, O; Erturhan, S; Seckiner, I; Sen, E; Sen, H; Yagci, F, 2015) |
| "Pre-cooling could induce similar injection pain relief to that of buffered lidocaine while maintaining longer postoperative anesthetic results than buffered lidocaine." | 9.20 | Prospective evaluation of pain and follow-up results when pre-cooling skin versus buffering lidocaine for upper blepharoplasty. ( Huang, L, 2015) |
| "We aimed to compare the effectiveness of esmolol 1 mg/kg and lidocaine 1 mg/kg for injection pain and for the prevention of rocuronium-induced withdrawal response." | 9.20 | Effects of pretreatment with esmolol and lidocaine on injection pain and rocuronium-induced withdrawal response. ( Akinci, M; Bumin Aydin, G; Ergil, J; Gürel, A; Kavak Akelma, F; Özkan, D, 2015) |
| "The results of our study showed that lidocaine puffs provided the best pain relief than the other analgesics used." | 9.20 | Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, pethidine & diclofenac sodium application for pain relief during fractional curettage: A randomized controlled trial. ( Acmaz, G; Aksoy, H; Başer, M; Bayraktar, E; Müderris, İİ; Yilmaz, MO, 2015) |
| "The aim of this study was to assess the efficacy in pain reduction of topical 2 % lidocaine compared to a placebo cream in children with oral mucosal lesions due to trauma or aphthous ulcers or in the prevention of clamp placement pain." | 9.19 | Phase III, randomized, double-blind, placebo-controlled trial of topical 2 % lidocaine for the prevention and treatment of oral mucosal pain in children. ( Artaud, C; Baaroun, V; Coudert, AE; Descroix, V; Druo, JP; Ifi-Naulin, C; Ostertag, A; Princ, G, 2014) |
| "To investigate the efficacy of pretreatment with cisatracurium for prevention of pain associated with propofol injection, and compare its efficacy with that of lidocaine." | 9.19 | Cisatracurium pretreatment with tourniquet reduces propofol injection pain: a double-blind randomized controlled trial. ( Kim, YH; Lim, CH; Namgung, J, 2014) |
| "5 mg/kg lidocaine with venous occlusion is recommended to prevent pain following injection of lipid emulsion propofol." | 9.19 | Intravenous lidocaine pretreatment with venous occlusion for reducing microemulsion propofol induced pain: comparison of three doses of lidocaine. ( Chae, YJ; Chang, HS; Joe, HB; Kim, DH; Kim, JA, 2014) |
| "We studied the analgesia provided by a lidocaine/tetracaine patch compared to injectable lidocaine during incision and drainage (I&D) of skin abscesses." | 9.19 | Injectable lidocaine provides similar analgesia compared to transdermal lidocaine/tetracaine patch for the incision and drainage of skin abscesses: a randomized, controlled trial. ( Bourne, CL; Brewer, KL; House, J, 2014) |
| "To determine if intrauterine administration of 5 cc of 2% lidocaine in addition to paracervical block reduces pain during laminaria insertion, when compared with paracervical block and saline placebo." | 9.19 | Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial. ( Liberty, A; Mercier, RJ, 2014) |
| "The combination of 3% mepivacaine plus 2% lidocaine with 1:100,000 epinephrine was equivalent to the combination of 2 cartridges of 2% lidocaine with 1:100,000 epinephrine in terms of injection pain, onset time, and pulpal anesthetic success for the IAN block." | 9.19 | Does the combination of 3% mepivacaine plain plus 2% lidocaine with epinephrine improve anesthesia and reduce the pain of anesthetic injection for the inferior alveolar nerve block? A prospective, randomized, double-blind study. ( Beck, M; Drum, M; Fowler, S; Lammers, E; Nusstein, J; Reader, A, 2014) |
| "The incidence of propofol-induced pain was significantly higher in the control group (39%) than in the other three groups (17% in the cooling group, 16% in the lidocaine group and 8% in the lidocaine plus cooling group)." | 9.19 | [Effectiveness of local cooling and lidocaine administration for prevention of pain upon injection of propofol]. ( Fujinaka, W; Takatori, M; Takubo, I; Terada, N, 2014) |
| "The results from our study indicate that injecting subcutaneous buffered lidocaine before intradermal injection of (99m)Tc-SC for breast lymphoscintigraphy significantly decreases patient pain without interfering with lymph node visualization." | 9.19 | Administration of subcutaneous buffered lidocaine prior to breast lymphoscintigraphy reduces pain without decreasing lymph node visualization. ( Baird, GL; Hawkins, AS; Movson, JS; Noto, RB; Powers, K; Yoo, DC, 2014) |
| "Between January 2006 and April 2009, 140 patients with early breast cancer were randomly assigned (1:1:1:1) to receive standard topical 4 % lidocaine cream and intradermal Tc-99m (control) or to one of three other study groups: topical placebo cream and injection of Tc-99m containing sodium bicarbonate (NaHCO3), 1 % lidocaine, or both." | 9.17 | Technical effects of adding 1 % lidocaine to technetium sulfur colloid for sentinel lymphatic mapping in early breast cancer: analysis of data from a double-blind randomized controlled trial. ( Arciero, CA; Avital, I; Bilchik, AJ; Buckenmaier Iii, CC; Henry, LR; Howard, RS; Peoples, GE; Stojadinovic, A, 2013) |
| "The authors tested the primary hypothesis that perioperative IV lidocaine administration during spine surgery (and in the postanesthesia care unit for no more than 8 h) decreases pain and/or opioid requirements in the initial 48 postoperative hours." | 9.17 | Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery. ( Benzel, E; Bingaman, W; Dalton, JE; Farag, E; Ghobrial, M; Kurz, A; Lee, JH; Liu, J; Sessler, DI; Zaky, S, 2013) |
| "The aim of this study was to determine whether pretreatment with alkalinised lignocaine reduced the incidence and severity of pain during propofol injection." | 9.17 | Effect of alkalinisation of lignocaine for propofol injection pain: a prospective, randomised, double-blind study. ( Aydogan, MS; Begec, Z; Colak, C; Erdogan, MA; Ozgul, U; Sanli, M, 2013) |
| "The study aimed to evaluate the effects of the pretreatment with lidocaine, fentanyl, and remifentanil using a venous occlusion technique in preventing pain caused by intravenous injection of rocuronium during induction of general anesthesia." | 9.17 | Comparison of three methods of preventing rocuronium induced pain on injection using venous occlusion technique: a randomized prospective double blind controlled study. ( Abu-Halaweh, NS; Abu-Halaweh, SA; Al-Hussami, MO; Al-Mustafa, M; Aloweidi, AK; Atyat, BS; Qudaisat, IY, 2013) |
| " There was a significantly lower mean pain score due to probe insertion in those patients who received topical diltiazem than in the placebo group (p<0." | 9.17 | Evaluation of the efficacy of a combination of diltiazem and periprostatic nerve block in pain control during transrectal ultrasonography-guided biopsy of the prostate. ( Biswas, G; Jindal, T; Karmakar, D; Mandal, SN, 2013) |
| "Treating minor lacerations with lidocaine-epinephrine-tetracaine before wound closure with tissue adhesive reduced ratings of pain and increased the proportion of pain-free repairs among children aged 3 months to 17 years." | 9.17 | Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children: a randomized controlled trial. ( Duncan, MJ; Harman, S; Petrcich, W; Ying, Y; Zemek, R, 2013) |
| "Lidocaine spray is an effective and practical alternative measure for reducing pain associated with electrical excision of the cervix during LEEP." | 9.17 | Lidocaine spray compared with submucosal injection for reducing pain during loop electrosurgical excision procedure: a randomized controlled trial. ( Charoenkwan, K; Vanichtantikul, A, 2013) |
| "Topical capsaicin 8% was developed for the treatment of peripheral neuropathic pain." | 9.17 | Comparison of cooling and EMLA to reduce the burning pain during capsaicin 8% patch application: a randomized, double-blind, placebo-controlled study. ( Knolle, E; Kovacs, GG; Medwed, S; Scharbert, G; Schemper, M; Zadrazil, M, 2013) |
| "Pertubation with lidocaine has been shown to reduce pain (on a VAS-scale) in women with endometriosis." | 9.17 | Quality of life in patients with endometriosis and the effect of pertubation with lidocaine - a randomized controlled trial. ( Bruse, C; Edelstam, G; Sjösten, A; Spira, J; Wickström, K, 2013) |
| "The goal of this study was to evaluate the effect of different methods of tourniquet application and lidocaine administration on MP injection pain." | 9.17 | Reducing the pain of microemulsion propofol injections: a double-blind, randomized study of three methods of tourniquet and lidocaine. ( Kim, HZ; Kim, K; Kim, NS; Kong, MH; Lee, DK; Lee, IO; Lim, BG; Sung Kim, Y, 2013) |
| "High efficacy of intrathecal methylprednisolone acetate (MPA) with lidocaine has been reported in a large patient group suffering from intractable postherpetic neuralgia (PHN)." | 9.17 | No beneficial effect of intrathecal methylprednisolone acetate in postherpetic neuralgia patients. ( Kalkman, CJ; Kavelaars, A; Meulenhoff, PC; Rijsdijk, M; van der Tweel, I; van Wijck, AJ, 2013) |
| "The lidocaine-ketamine combination is most effective for decreasing the pain on propofol injection." | 9.17 | A prospective, randomized, double-blind study to compare the efficacy of lidocaine + metoclopramide and lidocaine + ketamine combinations in preventing pain on propofol injection. ( Chaudhary, K; Gogia, AR; Gupta, P, 2013) |
| "This study was designed to evaluate the role of epidural methadone-lidocaine in cancer pain combined or not to epidural dexamethasone." | 9.17 | Epidural methadone results in dose-dependent analgesia in cancer pain, further enhanced by epidural dexamethasone. ( Lauretti, GR; Mattos, AL; Rizzo, CC; Rodrigues, SW, 2013) |
| "Post-operative pain scores and incision site reactions were compared in healthy dogs undergoing routine castration at a county animal shelter and assigned to two treatment groups, namely: (1) lidocaine/bupivacaine (1mg/kg lidocaine+1mg/kg bupivacaine mixture; n=17), or (2) placebo (0." | 9.17 | Comparison of the effect of intratesticular lidocaine/bupivacaine vs. saline placebo on pain scores and incision site reactions in dogs undergoing routine castration. ( Jones, CA; Lascelles, BD; Posner, LP; Stevens, BJ, 2013) |
| "Topical capsaicin and eutectic mixture of local anesthetics (EMLA) have been found to be equally effective in minimizing the pain of venipuncture." | 9.17 | A comparative evaluation of local application of the combination of eutectic mixture of local anesthetics and capsaicin for attenuation of venipuncture pain. ( Agarwal, A; Gupta, D; Kishore, K; Rastogi, S; Singh, PK; Singh, U, 2013) |
| "Lidocaine showed significantly reduced pain compared to placebo at all assessment points." | 9.16 | Local anesthetic effects of Lidocaine cream: randomized controlled trial using a standardized prick pain. ( Augustin, M; Herberger, K; Krause, K; Maier, K; Radtke, M; Zschocke, I, 2012) |
| "What's known on the subject? and What does the study add? Study Type - Harm Reduction RCT Level of Evidence 1b The combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block effectively counteracts probe and sampling related pain during transrectal prostate biopsy, but not pain due to periprostatic infiltration." | 9.16 | Combined perianal-intrarectal (PI) lidocaine-prilocaine (LP) cream and lidocaine-ketorolac gel provide better pain relief than combined PI LP cream and periprostatic nerve block during transrectal prostate biopsy. ( Bufo, P; Carrieri, G; Cormio, L; Lorusso, F; Pagliarulo, V; Perrone, A; Sanguedolce, F; Selvaggio, O, 2012) |
| "The aim of this study was to compare pain levels from arterial blood gas (ABG) sampling performed with or without application of lidocaine via jet injector." | 9.16 | Less painful arterial blood gas sampling using jet injection of 2% lidocaine: a randomized controlled clinical trial. ( Eslami, V; Farahmand, S; Hajiseyedjavady, H; Saeedi, M; Shahsavarinia, K, 2012) |
| "It has been reported in an open-label study that the combination of alkalinized lidocaine and heparin can immediately relieve the symptoms of urinary urgency, frequency, and pain associated with interstitial cystitis (IC)." | 9.16 | Alkalinized lidocaine and heparin provide immediate relief of pain and urgency in patients with interstitial cystitis. ( Davis, E; Franklin, A; Garner, WJ; Giesing, D; Kahn, BS; Koziol, J; Lakin, CM; Parsons, CL; Proctor, J; Zupkas, P, 2012) |
| " This study aimed to measure the incidence of propofol injection pain and evaluate the effect of lidocaine on pain caused during sedative upper GI endoscopic examinations." | 9.16 | Incidence of propofol injection pain and effect of lidocaine pretreatment during upper gastrointestinal endoscopy. ( Cho, KB; Chung, WJ; Hwang, JS; Jang, BK; Kim, ES; Kim, TY; Kwon, JS; Lee, JE; Park, KS; Park, WY, 2012) |
| "The aim of this randomized, double-blind, placebo-controlled study was to evaluate the effect of ephedrine pretreatment on the intensity of rocuronium injection pain when rocuronium was applied by timing principle and also to compare this effect with lidocaine and placebo." | 9.16 | Can ephedrine pretreatment be effective in alleviating rocuronium injection pain? ( Akcaboy, EY; Akcaboy, ZN; Gogus, N; Soyal, OB; Turhan, G, 2012) |
| "Although pretreatment with a 5% lidocaine patch was found to be a safe, effective, and simple method of preventing venipuncture pain in children, this method did not reduce drug injection pain during the induction of anesthesia." | 9.16 | Availability of a 5% lidocaine patch used prophylactically for venipuncture- or injection-related pain in children. ( Byeon, GJ; Kim, CH; Lee, HJ; Shin, SW; Yoon, JU; Yoon, JY, 2012) |
| "A significantly higher proportion of patients in the placebo group (83 %) experienced pain compared to the lidocaine and combination groups (43 and 7 %, respectively; both, P < 0." | 9.16 | Reduction of pain on injection of propofol: combination of nitroglycerin and lidocaine. ( Jeon, Y, 2012) |
| "To test the hypothesis that using Listerine mouthwash prior to administration of topical nasal lidocaine will result in improved pain and comfort outcomes during flexible nasolaryngoscopy (FNL)." | 9.16 | Pain and discomfort during flexible nasolaryngoscopy: a randomized, controlled trial assessing the efficacy of oral mouthwash and topical lidocaine. ( Bonaparte, JP; Corsten, M; Kilty, S; Odell, M, 2012) |
| "Intravenous perioperative lidocaine decreases the incidence and severity of PPSP after breast cancer surgery." | 9.16 | Perioperative intravenous lidocaine decreases the incidence of persistent pain after breast surgery. ( Grigoras, A; Lee, P; Sattar, F; Shorten, G, 2012) |
| "To compare the efficacy of pretreatment with parecoxib and lidocaine to prevent rocuronium injection pain." | 9.16 | Prevention of pain on injection of rocuronium: a comparison of lidocaine with different doses of parecoxib. ( Liu, J; Xiang, Y; Zhang, Y, 2012) |
| "To compare the effect of 1% lidocaine-epinephrine [1:100,000] buffered with sodium bicarbonate with skin cooling for 2 minutes with ice in reducing the pain of infiltration of anesthetic solution." | 9.16 | Prospective comparison between buffered 1% lidocaine-epinephrine and skin cooling in reducing the pain of local anesthetic infiltration. ( Al Shahwan, MA, 2012) |
| "kg(-1) and lidocaine 20 mg mixture significantly reduced propofol pain when compared with control group." | 9.16 | Prevention of propofol injection pain in children: a comparison of pretreatment with tramadol and propofol-lidocaine mixture. ( Borazan, H; Et, T; Kececioglu, A; Otelcioglu, S; Sahin, O; Uluer, MS, 2012) |
| " Pain scores among lidocaine and placebo arms were similar at tenaculum placement (lidocaine and placebo: median, 4; range, 0-10; P = ." | 9.16 | Cervical lidocaine for IUD insertional pain: a randomized controlled trial. ( Allsworth, JE; Madden, T; McNicholas, CP; Peipert, JF; Secura, G; Zhao, Q, 2012) |
| "To compare the level of pain and discomfort associated with subcutaneous infiltration of lidocaine diluted with normal saline to that associated with traditionally buffered lidocaine." | 9.16 | Virtually painless local anesthesia: diluted lidocaine proves to be superior to buffered lidocaine for subcutaneous infiltration. ( Aguilera, SB; Caperton, C; Chimento, S; Zaiac, M; Zaulyanov-Scanlan, L, 2012) |
| "02 mg, % 2 lidocaine 40 mg, metoclopramide 10 mg, and ketamine 100 microg/kg yields propofol induced pain 38%, 76%, 76%, and 58% respectively." | 9.16 | The effects of remifentanil, lidocaine, metoclopramide, or ketamine pretreatment on propofol injection pain. ( Aktay, M; Ozlü, O; Polat, R, 2012) |
| "This study evaluated the effects of topical lidocaine on skin sensation and on intradermal capsaicin-induced pain and hyperalgesia." | 9.15 | Effects of lidocaine patch on intradermal capsaicin-induced pain: a double-blind, controlled trial. ( Lam, VY; Schulteis, G; Wallace, M, 2011) |
| "To determine technical and clinical factors associated with pain when using an analgesic protocol with 50% nitrous oxide/oxygen and anesthetic cream (lidocaine and prilocaine, Emla(®)) for children with cerebral palsy undergoing botulinum toxin injections." | 9.15 | Determining the technical and clinical factors associated with pain for children undergoing botulinum toxin injections under nitrous oxide and anesthetic cream. ( Blajan, V; Brochard, S; Garlantezec, R; Houx, L; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2011) |
| "The lidocaine/flurbiprofen axetil combination, compared with lidocaine 40 mg or flurbiprofen 50 mg, effectively reduces pain during the injection of propofol." | 9.15 | Efficacy of the lidocaine/flurbiprofen axetil combination for reducing pain during the injection of propofol. ( Fujii, Y; Itakura, M, 2011) |
| " We intended to evaluate whether the addition of 10% lidocaine spray to a paracervical block decreases pain during cervical dilation and uterine aspiration." | 9.15 | Lidocaine spray in addition to paracervical block reduces pain during first-trimester surgical abortion: a placebo-controlled clinical trial. ( Alanbay, I; Başer, I; Ercan, CM; Karasahin, KE; Mesten, Z; Simsek, C, 2011) |
| "To determine the relative effectiveness of liposomal lidocaine, sucrose, and their combination for reducing pain in term newborns." | 9.15 | Effect of liposomal lidocaine and sucrose alone and in combination for venipuncture pain in newborns. ( Hogan, ME; Katz, J; Kikuta, A; Koren, G; Parvez, E; Shah, V; Stephens, D; Taddio, A, 2011) |
| " High dose intravenous opioids form the mainstay of procedural burns pain management; however it was suggested that intravenous lidocaine assists with minimising the pain experience." | 9.15 | Adjuvant use of intravenous lidocaine for procedural burn pain relief: a randomized double-blind, placebo-controlled, cross-over trial. ( Cleland, H; Costello, V; Ferraro, F; Konstantatos, A; Paul, E; Spinks, A; Wasiak, J, 2011) |
| "The aim of the present randomized clinical study was to assess the efficacy of simplex lidocaine in local anesthesia for inguinal hernia mesh-repairs, compare analgesia of three different concentrations of lidocaine, and explore use of lower concentrations of lidocaine in local anesthesia for inguinal hernia mesh-repairs." | 9.15 | Comparison of three concentrations of simplex lidocaine in local anesthesia for inguinal hernia mesh-repairs. ( Ban, LJ; Gong, YP; Lei, WZ; Liu, Y; Yang, L; Zeng, Y; Zhang, W, 2011) |
| "Pain frequency was 90% in the saline group, whereas the frequencies were significantly lower in the lidocaine and methylene blue groups (26." | 9.15 | Pain on injection of propofol: a comparison of methylene blue and lidocaine. ( Akinci, SB; Aypar, Ü; Salman, AE; Salman, MA; Saricaoglu, F, 2011) |
| "Pretreatment with combination of small-dose ephedrine and lidocaine could reduce the incidence and intensity of propofol-induced pain and also result in more stable hemodynamic profile, but however, the combination of two drugs failed to work better in further reduction of pain." | 9.15 | The effect of combined ephedrine and lidocaine pretreatment on pain and hemodynamic changes due to propofol injection. ( Kayalha, H; Khezri, MB, 2011) |
| "The addition of 3% sevoflurane at the time of preoxygenation for 1 min along with routine use of lidocaine-tourniquet completely prevented pain upon propofol injection, whereas sevoflurane by itself provided similar analgesia to premixed lidocaine with propofol." | 9.15 | Sevoflurane to alleviate pain on propofol injection. ( Ali, MS; DeSousa, K, 2011) |
| "Rapid injection was less painful than after pretreatment with lidocaine 0." | 9.15 | Rapid injection of propofol reduces vascular pain and facilitates Laryngeal Mask Airway insertion. ( Inomata, S; Shimizu, T; Tanaka, M, 2011) |
| "This trial will define the role of 2% lidocaine in the treatment of painful infectious mouth conditions." | 9.15 | A double blind, randomised placebo controlled trial of topical 2% viscous lidocaine in improving oral intake in children with painful infectious mouth conditions. ( Babl, FE; Hopper, SM; Lee, KJ; McCarthy, M; Oakley, E; Tancharoen, C, 2011) |
| "To determine if the intravenous co-administration of equal volumes of lidocaine and nalbuphine, with undiluted normal saline, prevents injection pain caused by nalbuphine." | 9.15 | Equal volumes of undiluted nalbuphine and lidocaine and normal diluted saline prevents nalbuphine-induced injection pain. ( Chau, SW; Chen, MK; Cheng, KI; Feng, YT; Ku, CL; Shen, YC; Wang, FY, 2011) |
| "The aim of this study was to compare the efficacy of topical piroxicam and EMLA cream on pain control and subsequent inflammation in neodymium:yttrium-aluminum-garnet (Nd:YAG) 1,064 nm laser hair removal in female volunteers." | 9.14 | A clinical comparison of topical piroxicam and EMLA cream for pain relief and inflammation in laser hair removal. ( Akinturk, S; Eroglu, A, 2009) |
| "To determine the effectiveness of lidocaine 2% gel vstetracaine 1% drops in primary pterygium surgery." | 9.14 | Randomised controlled trial on the effectiveness of lidocaine gel vs tetracaine drops as the sole topical anaesthetic agent for primary pterygium surgery. ( Cheng, LL; Lam, DS; Lam, PT; Lau, TT; Leung, GY; Young, AL, 2009) |
| "Our findings suggest that the combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block provides better pain control than the 2 modalities alone during the sampling part of transrectal ultrasound guided prostate biopsy with no increase in the complication rate." | 9.14 | Combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block for pain control during transrectal ultrasound guided prostate biopsy: a randomized, controlled trial. ( Autorino, R; Barbone, F; De Maria, M; Di Lorenzo, G; Giannarini, G; Manassero, F; Mogorovich, A; Morelli, G; Selli, C; Valent, F, 2009) |
| "Sodium amobarbital decreased spontaneous pain by 73% (vs 46% with lidocaine) and normalized sensory abnormalities at or above the level of injury in 3 patients (as compared to just 1 patient with lidocaine), 2 of whom had transitional zone allodynia/hyperalgesia." | 9.14 | Effects of intravenous sodium amobarbital vs lidocaine on pain and sensory abnormalities in patients with spinal cord injury. ( Bharatwal, B; Krassioukov, AV; Mailis-Gagnon, A; Yegneswaran, B, 2009) |
| "A common drawback of propofol is pain on injection and lignocaine is commonly mixed with propofol to reduce the incidence and severity of this pain." | 9.14 | Prevention of propofol pain: a comparative study. ( Jayaraman, L; Sethi, M; Sethi, N; Sharma, S; Sood, J, 2009) |
| "A metered-dose 8% lidocaine pump spray produced prompt analgesia in patients with PBFD-related pain without severe side effects." | 9.14 | 8% Lidocaine pump spray relieves pain associated with peripheral blood flow disorders. ( Kanai, A; Suzuki, A, 2009) |
| "The aim of this study was to evaluate whether the use of lidocaine 10% spray was effective in pain control during hysterosalpingography (HSG)." | 9.14 | Lidocaine 10% spray reduces pain during hysterosalpingography: a randomized controlled trial. ( Alanbay, I; Baser, I; Gezginc, K; Karasahin, E; Keskin, U, 2009) |
| "The objectives were to determine whether pretreatment with needleless jet-delivered lidocaine decreases self-reported pain in children undergoing needle insertion in the emergency department (ED) and to explore whether pretreatment with a jet device decreases self-reported pain in children undergoing needle insertion in the ED." | 9.14 | A randomized, double-blind controlled study of jet lidocaine compared to jet placebo for pain relief in children undergoing needle insertion in the emergency department. ( Auerbach, M; Mojica, M; Tunik, M, 2009) |
| "Perianal anesthesia with lidocaine-prilocaine cream may solely be sufficient to decrease the pain during prostate biopsy." | 9.14 | Is only perianal anesthesia with lidocaine-prilocaine cream sufficient to decrease the pain during transrectal ultrasound-guided prostate biopsy? A prospective randomized study. ( Kandirali, E; Metin, A; Semercioz, A; Serin, E; Ulukaradag, E; Uysal, B, 2009) |
| "In patients with PHN and painful DPN failing to respond to monotherapy, combination therapy with 5% lidocaine medicated plaster and pregabalin provides additional clinically relevant pain relief and is safe and well-tolerated." | 9.14 | Efficacy and safety of combination therapy with 5% lidocaine medicated plaster and pregabalin in post-herpetic neuralgia and diabetic polyneuropathy. ( Baron, R; Binder, A; Leijon, G; Mayoral, V; Serpell, M; Steigerwald, I, 2009) |
| "To compare efficacy and safety of 5% lidocaine medicated plaster with pregabalin in patients with post-herpetic neuralgia (PHN) or painful diabetic polyneuropathy (DPN)." | 9.14 | 5% lidocaine medicated plaster versus pregabalin in post-herpetic neuralgia and diabetic polyneuropathy: an open-label, non-inferiority two-stage RCT study. ( Baron, R; Binder, A; Leijon, G; Mayoral, V; Serpell, M; Steigerwald, I, 2009) |
| "Our study demonstrated that the combination treatment of two different analgesic modalities, alfentanil and lidocaine, could prevent the moderate and severe pain on propofol injection, and reduce the incidence of mild pain compared with each drug alone." | 9.14 | Prevention of propofol-induced pain in children: combination of alfentanil and lidocaine vs alfentanil or lidocaine alone. ( Kim, JS; Kim, JY; Kwak, HJ; Min, SK, 2009) |
| "The purpose of this study was to compare the effectiveness of topically applied lidocaine-prilocaine (EMLA) cream with local anesthetic infiltration in the reduction of pain during perineal suturing after childbirth." | 9.14 | Comparison between lidocaine-prilocaine cream (EMLA) and mepivacaine infiltration for pain relief during perineal repair after childbirth: a randomized trial. ( Cromi, A; Franchi, M; Gaudino, F; Ghezzi, F; Scarperi, S; Siesto, G, 2009) |
| "We conducted a prospective randomized study to assess the effects of preceding lidocaine on the incidence and intensity of propofol-induced pain." | 9.14 | [Effects of the injection method of lidocaine on preventing injection pain during anesthesia induction by target controlled infusion with propofol]. ( Kajiyama, S; Okada, Y; Osawa, Y, 2009) |
| "To investigate the alleviation effect of vein pretreatment and granisetron/lidocaine combination on propofol injection-induced pain." | 9.14 | [Effects of granisetron/lidocaine combination on propofol injection-induced pain: a double-blind randomized clinical trial]. ( Lin, XM; Ma, YS; Zhou, J, 2009) |
| "It is a common practice for medical practitioners to use subcutaneous infiltration of lidocaine to alleviate the pain of intravenous cannulation or line insertion." | 9.14 | The effect of needle bevel position on pain for subcutaneous lidocaine injection. ( Arheart, KL; Birnbach, DJ; Candiotti, K; Curia, L; Koyyalamudi, P; Rodriguez, Y, 2009) |
| "Between Jan 13, 2006, and April 30, 2009, 140 patients with early breast cancer were randomly assigned in a 1:1:1:1 fashion to receive the standard topical 4% lidocaine cream and injection of [(99m)Tc]Tc-sulfur colloid (n=35), or to one of three other study groups: topical placebo cream and injection of Tc-sulfur colloid containing either sodium bicarbonate (n=35), 1% lidocaine (n=35), or sodium bicarbonate and 1% lidocaine (n=35)." | 9.14 | Standard versus pH-adjusted and lidocaine supplemented radiocolloid for patients undergoing sentinel-lymph-node mapping and biopsy for early breast cancer (PASSION-P trial): a double-blind, randomised controlled trial. ( Buckenmaier, CC; Henry, LR; Howard, RS; Jurgens, JS; Kwon, KH; Peoples, GE; Schuyler, B; Shriver, CD; Stojadinovic, A, 2009) |
| "5 mg kg(-1) for prevention of propofol induced pain." | 9.14 | Prevention of pain on injection of propofol: a comparison of lidocaine with different doses of paracetamol. ( Borazan, H; Erdem, TB; Kececioglu, M; Otelcioglu, S, 2010) |
| " Patients receiving lidocaine reported less pain than control patients during the dressing change (4." | 9.14 | The impact of topical lidocaine on pain level assessment during and after vacuum-assisted closure dressing changes: a double-blind, prospective, randomized study. ( Agarwal, JP; Drum, M; Franczyk, M; Gottlieb, LJ; Lohman, RF; Rupani, G, 2009) |
| "The objective of this study was to compare the efficiency oflidocaine with that of plain saline for paracervical pain relief during fractional curettage." | 9.14 | Comparison of lidocaine 1% and normal saline in paracervical anesthesia for decreasing of pain in curettage. ( Alavi, A; Aliabadi, E; Amirian, M; Rajai, M; Zare, S, 2009) |
| "The aim of this study was to compare the efficacy of intravenous pretreatment with fentanyl 50 microg, fentanyl 100 microg, and lidocaine 40 mg, preceded by venous occlusion, for reducing pain on injection of propofol in adult Japanese surgical patients." | 9.14 | A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients. ( Fujii, Y; Itakura, M, 2009) |
| " Each of the four propofol solutions was administered 88 times; of patients receiving Baxter propofol+saline, 74 (84%) had pain; when mixed with 2% lidocaine 45 (50." | 9.14 | Pain on injection from propofol may be avoided by changing its formulation. ( Alcover, J; Aldrete, JA; Johnson, SC; Montpetit, FH; Otero, P; Parietti, A; Quiroga, D; Torrieri, A, 2010) |
| "The lidocaine patch 5% does not significantly improve pain control in polytrauma patients with traumatic rib fractures." | 9.14 | Randomized, double-blind, placebo-controlled trial using lidocaine patch 5% in traumatic rib fractures. ( Bettendorf, M; Frye, I; Horton, ZA; Ingalls, NK; Rodriguez, C, 2010) |
| "Topical lidocaine (LDC) treatment using a gel or patch preparation is effective in the treatment of postherpetic neuralgia (PHN), but neither is suited for the eye in patients with ophthalmic PHN." | 9.14 | Lidocaine eye drops attenuate pain associated with ophthalmic postherpetic neuralgia. ( Kanai, A; Niki, Y; Okamoto, H; Okamoto, T; Suzuki, K, 2010) |
| "The aim of this study was to evaluate the efficacy of a combined topical and local anesthesia consisting of a transrectal lidocaine suppository followed by periprostatic nerve block (PNB) in comparison to the combination of transrectally applied lidocaine gel followed by PNB and PNB alone as methods of reducing pain during transrectal prostate biopsy." | 9.14 | Addition of lidocaine suppositories to periprostatic nerve block enhances pain control in prostate biopsies: a placebo-controlled randomized trial. ( Fink, KG; Paras, L; Szlauer, R, 2010) |
| "Injection pain during propofol administration can be particularly distressing in children." | 9.14 | Does the newer preparation of propofol, an emulsion of medium/long chain triglycerides cause less injection pain in children when premixed with lignocaine? ( Krishna, HM; Nittala, A; Varghese, E, 2010) |
| "To compare the effectiveness of a combination of intrauterine lignocaine and vaginal misoprostol in reducing pain at hysteroscopy and endometrial aspiration (EA)." | 9.14 | Efficacy of intrauterine lignocaine plus vaginal misoprostol for pain relief in premenopausal women undergoing endometrial aspiration and ambulatory hysteroscopy. ( Dadhwal, V; Gupta, B; Gupta, N; Mittal, S, 2010) |
| " lidocaine in reducing pain from i." | 9.14 | Vapocoolant spray vs subcutaneous lidocaine injection for reducing the pain of intravenous cannulation: a randomized, controlled, clinical trial. ( Page, DE; Taylor, DM, 2010) |
| "In a randomized double-blinded clinical trial, 150 patients (50 per group) with irreversible pulpitis were given placebo, 600 mg ibuprofen, or 75 mg indomethacin 1 hour before local anesthesia." | 9.14 | The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis. ( Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR, 2010) |
| "Pain score results showed that the use of intrarectal lidocaine spray provided significantly better pain control than cream and anaesthetic gel." | 9.14 | Lidocaine spray administration during transrectal ultrasound guided prostate biopsy modified the discomfort and pain of the procedure: results of a randomized clinical trial. ( Daniele, C; Dell'Atti, L, 2010) |
| "The addition of lidocaine substantially reduces the pain of LGP-HA injection without altering safety." | 9.14 | A lidocaine-containing formulation of large-gel particle hyaluronic acid alleviates pain. ( Bank, D; Brandt, F; Cross, SL; Weiss, R, 2010) |
| "To compare the efficacy of 2% lidocaine "timing" on alleviation of pain upon induction using propofol or etomidate." | 9.14 | Does lidocaine more effectively prevent pain upon induction with propofol or etomidate when given preemptively than when mixed with the drug? ( Brock, MF; Grace, BE; Groban, L; Hillegass, G; Houle, TT; Morley, B, 2010) |
| "To compare the efficacy and side effects profile of topical 2% lidocaine gel with injectable 2% lidocaine solution as local anaesthetics for incision and curettage of chalazion." | 9.14 | Comparison of topical lidocaine [2% gel] and injectable lidocaine [2% solution] for incision and curettage of chalazion in Ilorin, Nigeria. ( Bolaji, BO; Mahmoud, AO; Osayande, OO, 2010) |
| "To determine the effect of lidocaine gel on pain from TCu-380AIUD insertion." | 9.14 | Effect of lidocaine gel on pain from copper IUD insertion: a randomized double-blind controlled trial. ( Kazemi, F; Mohammad-Alizadeh-Charandabi, S; Seidi, S, 2010) |
| "Pain on injection limits the use of propofol in children." | 9.13 | Avoiding propofol injection pain in children: a prospective, randomized, double-blinded, placebo-controlled study. ( Boufroukh, D; Bringuier, S; Capdevila, X; Dadure, C; Hocquet, AF; Lubrano, JF; Raux, O; Rochette, A, 2008) |
| "The overall incidence of pain on injection was 31/133 (23%) in the propofol-MCT/LCT plus lidocaine group vs." | 9.13 | Does addition of lidocaine to medium- and long-chain triglyceride propofol emulsions significantly reduce pain on injection? ( Jamjamrat, G; Kosittanasan, S; Krobbuaban, B; Kumkeaw, S; Siriwan, D; Tanomsat, M; Thanetses, K, 2008) |
| "To compare the efficacy of oral naproxen with intrauterine instillation of 1% lignocaine for pain relief in women undergoing hysterosalpingography (HSG) as an infertility investigation." | 9.13 | Comparison of oral naproxen and intrauterine lignocaine instillation for pain relief during hysterosalpingography. ( Ghosh, B; Gupta, N; Mittal, S, 2008) |
| "To study the effect of the venous occlusion duration using lidocaine on the incidence and severity of propofol induced pain." | 9.13 | Duration of venous occlusion with lidocaine for preventing propofol induced pain. ( Abu-Ali, HM; Al-Ghanem, SA; Ammari, BA; Badran, IZ; Daradkeh, SS; Massad, IM, 2008) |
| " With respect to pain intensity, mean pain score was significantly less in the combination group than in the lidocaine or dexamethasone groups (P<0." | 9.13 | Efficacy of combination intravenous lidocaine and dexamethasone on propofol injection pain: a randomized, double-blind, prospective study in adult Korean surgical patients. ( Ha, J; Jeon, Y; Kim, Y; Kwak, KH, 2008) |
| "The use of intrarectal lidocaine gel did not demonstrated being more effective in pain control in our series than the use of lubricant gel, but lidocaine injected into the apex and seminal vesicles was." | 9.13 | [Ultrasound guided transrectal prostatic biopsy and pain. Prospective randomized study comparing lubricant gel, lidocaine gel, and anesthetic blockage of the neurovascular bundles with 1% lidocaine]. ( Argüelles Salido, E; Campoy Martínez, P; Conde Sánchez, JM; Congregado Ruiz, CB; Medina López, RA; Ruiz Zafra, V, 2008) |
| "We studied the effect of fentanyl pretreatment on alleviating pain during the injection of Propofol-Lipuro." | 9.13 | Fentanyl pre-treatment alleviates pain during injection of propofol-lipuro premixed with lignocaine. ( Ahmad, N; Balan, S; Zanariah, Y, 2008) |
| "To compare pain control results between periprostatic nerve block alone and combined with topical prilocaine-lidocaine cream as local anesthesia of prostate biopsy." | 9.13 | Topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial. ( Briganti, A; Dehò, F; Di Girolamo, V; Gallina, A; Montorsi, F; Raber, M; Rigatti, P; Roscigno, M; Salonia, A; Scattoni, V, 2008) |
| " acetaminophen seems to be effective in attenuating pain during i." | 9.13 | Efficacy of intravenous acetaminophen and lidocaine on propofol injection pain. ( Arun, O; Canbay, O; Celebi, N; Karagöz, AH; Ozgen, S; Saricaoğlu, F, 2008) |
| "Oral amitriptyline, a tricyclic antidepressant, is effective for treating neuropathic pain." | 9.13 | Topical amitriptyline versus lidocaine in the treatment of neuropathic pain. ( Ho, KY; Huh, BK; Miller, EJ; White, WD; Yeh, CC, 2008) |
| "The aim of this study was to compare the efficacy of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients." | 9.13 | Comparison of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, parallel-group, placebo-controlled study. ( Fujii, Y; Itakura, M, 2008) |
| "The Comparison of Venipuncture and Venous Cannulation Pain After Fast-Onset Needle-Free Powder Lidocaine or Placebo Treatment trial was a randomized, single-dose, double-blind, phase 3 study investigating whether a needle-free powder lidocaine delivery system (a sterile, prefilled, disposable system that delivers lidocaine powder into the epidermis) produces effective local analgesia within 1 to 3 minutes for venipuncture and peripheral venous cannulation procedures in children." | 9.13 | Needle-free powder lidocaine delivery system provides rapid effective analgesia for venipuncture or cannulation pain in children: randomized, double-blind Comparison of Venipuncture and Venous Cannulation Pain After Fast-Onset Needle-Free Powder Lidocaine ( Bean-Lijewski, J; Gennevois, DJ; Kauffman, RE; Koh, JL; Malviya, SV; Richards, PT; Rose, JB; Zempsky, WT, 2008) |
| " Mean +/- SD Modified Behavioral Pain Scale pain scores for EMLA, nitrous oxide/oxygen, and nitrous oxide/oxygen plus EMLA were, respectively, 9." | 9.13 | EMLA cream and nitrous oxide to alleviate pain induced by palivizumab (Synagis) intramuscular injections in infants and young children. ( Annequin, D; Biran, V; Carbajal, R; Cimerman, P; Epaud, R; Fauroux, B; Gold, F; Lenclen, R; Thibault, P, 2008) |
| "To systematically and meta-analytically examine the efficacy of ropivacaine versus lidocaine infiltration for controlling postpartum perineal pain secondary to spontaneous tear or selective episiotomy." | 9.12 | Ropivacaine versus lidocaine infiltration for postpartum perineal pain: A systematic review and meta-analysis. ( Abu-Zaid, A; Abuzaid, M; Al-Badawi, IA; Alomar, O; Baradwan, S; Kadah, KA; Magzoub, D; Salem, H, 2021) |
| "A research was performed to review the effect of pharmacological interventions to control the propofol injection pain." | 9.12 | Pharmacological control of pain during propofol injection: a systematic review and meta-analysis. ( Bakhtiari, E; Gharavi Fard, M; Mousavi, SH, 2021) |
| "Our purpose was to compare the pain induced by infiltration of the skin with 1% lidocaine with epinephrine 1:100,000 buffered with sodium bicarbonate (buffered) versus 1% lidocaine freshly mixed with epinephrine (fresh)." | 9.12 | Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine. ( Brown, MD; Burns, CA; Cooper, JZ; Feng, C; Ferris, G, 2006) |
| "Ketamine significantly reduced ongoing pain and evoked pain to brush and pinprick, whereas lidocaine only reduced evoked pain to repetitive pinprick stimuli." | 9.12 | Differential effect of ketamine and lidocaine on spontaneous and mechanical evoked pain in patients with nerve injury pain. ( Bach, FW; Gottrup, H; Jensen, TS; Juhl, G, 2006) |
| "To compare the level of pain experienced by patients during transrectal ultrasound-guided prostatic biopsy using intrarectal 2% lidocaine gel versus plain lubricant gel." | 9.12 | Intrarectal administration of lidocaine gel versus plain lubricant gel for pain control during transrectal ultrasound-guided extensive 10-core prostate biopsy in Hong Kong Chinese population: prospective double-blind randomised controlled trial. ( Cheung, MC; Ho, KL; Lee, FC; Leung, SY; Tam, PC; Wong, BB, 2006) |
| "To evaluate the effectiveness and acceptability of a lidocaine spray in reducing perineal pain during spontaneous vaginal delivery." | 9.12 | Effectiveness and acceptability of lidocaine spray in reducing perineal pain during spontaneous vaginal delivery: randomised controlled trial. ( Campbell, R; Peters, TJ; Sanders, J, 2006) |
| "Previous studies found that lidocaine addition to propofol long-chain triglyceride was associated with a lower incidence of injection pain than medium-chain triglyceride/long-chain triglyceride formulation, but the incidence was still high (31-40%)." | 9.12 | Preventing pain during injection of propofol: effects of a new emulsion with lidocaine addition. ( Bachmann-Mennenga, B; Boedeker, RH; Heesen, M; Mann, M; Mühlenbruch, B; Ohlmer, A, 2007) |
| "Of the 4 methods studied, the optimal method to decrease the incidence and intensity of pain resulting from propofol injection is to inject lidocaine while applying venous occlusion for 60 seconds prior to administering propofol." | 9.12 | Venous occlusion with lidocaine for preventing propofol induced pain. A prospective double-blind randomized study. ( Abu-Ali, HM; Abu-Halaweh, SA; Badran, IZ; Massad, IM, 2006) |
| "Propofol is associated with a high incidence of injection pain in children, even if given together with lidocaine." | 9.12 | Etomidate-Lipuro is associated with considerably less injection pain in children compared with propofol with added lidocaine. ( Eksborg, S; Lönnqvist, PA; Nyman, Y; Palm, C; Von Hofsten, K, 2006) |
| "Administering 75 mg tramadol/650 mg acetaminophen orally with periprostatic 1% lidocaine before transrectal ultrasound guided prostate biopsy is a safe, easy and effective method of controlling pain during the biopsy procedure." | 9.12 | Combination of oral tramadol, acetaminophen and 1% lidocaine induced periprostatic nerve block for pain control during transrectal ultrasound guided biopsy of the prostate: a prospective, randomized, controlled trial. ( Carvin, DM; Costa, J; Pendleton, J; Rosser, CJ; Wludyka, P, 2006) |
| "We examined the effect of lidocaine pretreatment before propofol administration on the incidence of transient motor disturbances and on propofol requirements for anesthesia induction in infants and children undergoing repeated painful diagnostic and therapeutic hematological procedures." | 9.12 | Lidocaine pretreatment for the prevention of propofol-induced transient motor disturbances in children during anesthesia induction: a randomized controlled trial in children undergoing invasive hematologic procedures. ( Annino, L; Bilotta, F; Favaro, R; Ferri, F; Rosa, G; Soriano, SG, 2006) |
| "To evaluate the influence of aging on lidocaine requirements for propofol-induced pain on injection." | 9.12 | Influence of aging on lidocaine requirements for pain on injection of propofol. ( Fujii, Y; Shiga, Y, 2006) |
| "Previous injection of diphenhydramine with venous occlusion can be considered as an alternative to lidocaine for reducing the prevalence of pain caused by injection of propofol into peripheral veins." | 9.12 | Comparison of diphenhydramine and lidocaine for prevention of pain after injection of propofol: a double-blind, placebo-controlled, randomized study. ( Apiliogullari, B; Apiliogullari, S; Balasar, M; Duman, A; Keles, B; Yilmaz, H, 2007) |
| "35 microg kg(-1) min(-1)) and a premixture of lidocaine with propofol (mixture of propofol 1% and lidocaine 1% in a 10:1 ratio) was compared with either treatment alone in the prevention of pain on propofol injection." | 9.12 | Reduction of pain on injection of propofol: combination of pretreatment of remifentanil and premixture of lidocaine with propofol. ( Baek, W; Jeon, Y; Kim, J; Kim, S; Kwak, K; Lim, D; Park, S, 2007) |
| " The addition of epinephrine to lidocaine significantly reduced superficial bleeding." | 9.12 | Local infiltration of epinephrine-containing lidocaine with bicarbonate reduces superficial bleeding and pain during labor epidural catheter insertion: a randomized trial. ( Brummel, C; Carvalho, B; Cohen, SE; Fuller, A, 2007) |
| "To compare the efficacy and tolerance profile of saline-diluted botulinum toxin A and lidocaine-diluted botulinum toxin A in patients with axillary hyperhidrosis." | 9.12 | Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline: a randomized, side-by-side, double-blind study. ( Simonart, T; Vadoud-Seyedi, J, 2007) |
| "Topical application of EMLA and Oraqix before palatal anesthetic infiltration is associated with less pain than with benzocaine gel." | 9.12 | Comparison of topical anesthetics (EMLA/Oraqix vs. benzocaine) on pain experienced during palatal needle injection. ( Al-Melh, MA; Andersson, L, 2007) |
| "To compare the efficacy and side effects of transdermal diclofenac patch with eutectic mixture of local anesthetic (EMLA) cream in attenuating venous cannulation pain." | 9.12 | Transdermal diclofenac patch vs eutectic mixture of local anesthetics for venous cannulation pain. ( Agarwal, A; Gautam, S; Gupta, D; Singh, U, 2007) |
| "The aim of the study was to demonstrate that repeated anorectal administration of a 5% lidocaine ointment (CAS 137-58-6; LidoPosterine Salbe, Posterisan akut Rektalsalbe) in the treatment of patients with acute anorectal pain does not result in systemically efficacious plasma concentrations of lidocaine." | 9.12 | Proof of systemic safety of a lidocaine ointment in the treatment of patients with anorectal pain. ( Mazur, D; Schlegelmilch, R; Seiler, D; Vens-Cappell, B; Zimmermann, J, 2007) |
| "We conducted this randomized double-blind trial to determine the extent of further pain reduction by adding lidocaine to Lipuro propofol." | 9.12 | Lidocaine is more efficient than the choice of propofol formulations to reduce incidence of pain on induction. ( Elliot, SC; Krishnan, K; Mallick, A; Vucevic, M, 2007) |
| "To our knowledge, this is the first study demonstrating that the needle-free delivery of lidocaine is an effective, useful, and noninvasive method of providing local anesthesia for the FNAB of thyroid nodules." | 9.12 | Needle-free delivery of lidocaine for reducing the pain associated with the fine-needle aspiration biopsy of thyroid nodules: time-saving and efficacious procedure. ( Demirag, NG; Demirer, AN; Ertugrul, DT; Gursoy, A; Sahin, M; Tutuncu, NB, 2007) |
| "The combination of two different analgesic modalities, remifentanil and lidocaine completely abolishes moderate and severe pain associated with propofol injection, and significantly reduces the incidence of mild pain when compared with each drug used alone." | 9.12 | Multimodal analgesia to prevent propofol-induced pain: pretreatment with remifentanil and lidocaine versus remifentanil or lidocaine alone. ( Al-Alami, AA; Aouad, MT; Baraka, AS; Siddik-Sayyid, SM, 2007) |
| "7%) complained of pain in the lidocaine plus remifentanil group compared with 15 (35." | 9.12 | A combination of lidocaine (lignocaine) and remifentanil reduces pain during propofol injection. ( Choi, G; Chung, H; Han, C; Jeon, Y; Kim, S; Kwak, K; Lim, C; Lim, D, 2007) |
| "Injection pain was twice as common with ketamine-propofol admixture than with lidocaine-propofol admixture." | 9.12 | A ketamine-propofol admixture does not reduce the pain on injection compared with a lidocaine-propofol admixture. ( Abdelaziz, AB; Cherif, R; Chettaoui, O; Kaabachi, O; Kokki, H; Ouezini, R, 2007) |
| "Pain on injection is a recognized adverse event (AE) with propofol, an agent used to induce general anesthesia in surgical patients." | 9.12 | Prevention of pain due to injection of propofol with IV administration of lidocaine 40 mg + metoclopramide 2.5, 5, or 10 mg or saline: a randomized, double-blind study in Japanese adult surgical patients. ( Fujii, Y; Nakayama, M, 2007) |
| "The incidence of pain on injection of propofol MCT/LCT was not different from that caused by propofol LCT with pretreatment of lidocaine and the intensity of pain on propofol MCT/LCT injection decreased significantly when using lidocaine pretreatment." | 9.12 | Pain on injection of propofol: propofol LCT vs propofol MCT/LCT with or without lidocaine pretreatment. ( Burimsittichai, R; Charuluxananan, S; Kumwilaisuk, K; Premsamran, P; Sathapanawath, N; Tingthanathikul, W, 2006) |
| "Various strategies have been studied to reduce the discomfort of rocuronium pain." | 9.12 | Effect of narcotic pretreatment on pain after rocuronium injection: a randomized, double-blind controlled comparison with lidocaine. ( Bithal, PK; Chauhan, H; Dash, HH; Prabhakar, H; Rath, GP; Singh, M, 2007) |
| "Propofol, a commonly used anesthetic, often causes pain on injection." | 9.12 | Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine. ( Boker, A; Ertok, E; Saadawy, I, 2007) |
| " We evaluated the patient's perception of pain/discomfort experienced during the procedure in terms of the type of anesthesia used: periprostatic infiltration with 2% lidocaine, or intrarectal instillation of lidocaine-prilocain cream." | 9.11 | Pain during transrectal ultrasonography guided prostate biopsy: a randomized prospective trial comparing periprostatic infiltration with lidocaine with the intrarectal instillation of lidocaine-prilocain cream. ( Adamakis, I; Alamanis, C; Giannopoulos, A; Haritopoulos, K; Mitropoulos, D; Stravodimos, K, 2004) |
| "Pain on injection caused by Propofol-LCT with pre-treatment of lidocaine and Propofol-MCT/LCT alone is shown to be equivalent." | 9.11 | [Propofol-LCT versus propofol-MCT/LCT with or without lidocaine - a comparison on pain on injection]. ( Haaf-Von-Below, S; Kuhlen, R; Kunitz, O; Lösing, R; Rossaint, R; Schulz-Stübner, S, 2004) |
| "To investigate the effects of IV lidocaine on spontaneous and evoked pain (allodynia and hyperalgesia) due to peripheral nerve injury (postherpetic neuralgia or nerve trauma) using quantitative sensory testing." | 9.11 | Systemic lidocaine in pain due to peripheral nerve injury and predictors of response. ( Attal, N; Bouhassira, D; Brasseur, L; Chauvin, M; Rouaud, J, 2004) |
| "Intravenous magnesium and lidocaine pretreatment are equally effective in attenuating propofol-induced pain." | 9.11 | Vein pretreatment with magnesium sulfate to prevent pain on injection of propofol is not justified. ( Agarwal, A; Dhiraj, S; Gupta, D; Pandey, CK; Pandey, R; Raza, M; Singh, PK; Singh, U, 2004) |
| "The purpose of this prospective, randomized, double-blind study was to compare injection pain and postinjection pain of 2% lidocaine with 1:100,000 epinephrine and 3% mepivacaine using the computer-assisted Wand Plus injection system to administer the palatal-anterior superior alveolar (P-ASA) injection." | 9.11 | Injection pain and postinjection pain of the palatal-anterior superior alveolar injection, administered with the Wand Plus system, comparing 2% lidocaine with 1:100,000 epinephrine to 3% mepivacaine. ( Beck, M; Burns, Y; Nusstein, J; Reader, A; Weaver, J, 2004) |
| "Propofol causes pain on IV injection in 28%-90% of patients." | 9.11 | Pretreatment with thiopental for prevention of pain associated with propofol injection. ( Agarwal, A; Ansari, MF; Dhiraj, S; Gupta, D; Pandey, R; Raza, M; Singh, PK; Singh, U, 2004) |
| "Ketamine but not lidocaine showed a significant analgesic effect in patients with neuropathic pain after spinal cord injury." | 9.11 | The analgesic effect of intravenous ketamine and lidocaine on pain after spinal cord injury. ( Gordh, T; Karlsten, R; Kvarnström, A; Quiding, H, 2004) |
| "We found no difference in pain between the intrauterine-lidocaine and placebo groups." | 9.11 | The use of intrauterine lidocaine to minimize pain during hysterosalpingography: a randomized trial. ( Frishman, GN; Plosker, S; Shafi, F; Spencer, PK; Weitzen, S, 2004) |
| "To study the effects of an intrauterine lidocaine infusion on perceived patient pain in first-trimester abortions and to measure serum lidocaine levels." | 9.11 | Intrauterine lidocaine infusion for pain management in first-trimester abortions. ( Astley, S; Edelman, A; Jensen, JT; Leclair, C; Nichols, MD; Shy, K, 2004) |
| "To clarify whether the therapeutic indication for a lidocaine patch to treat postherpetic neuralgia can be extended to include other focal peripheral neuropathic pain syndromes, we performed a subgroup analysis of a placebo-controlled, double-blind randomized study." | 9.11 | [Reduction of chronic pain for non-postherpetic peripheral neuropathies after topical treatment with a lidocaine patch]. ( Faust, M; Hüppe, M; Meier, T; Schmucker, P, 2004) |
| "Propofol causes pain or discomfort on injection in 28%-90% of patients." | 9.11 | Pain during injection of propofol: the effect of prior administration of butorphanol. ( Agarwal, A; Dhiraaj, S; Gupta, D; Pandey, CK; Pandey, R; Raza, M; Singh, PK; Singh, U, 2004) |
| "Propofol is well known for its association with pain on injection." | 9.11 | Propofol-induced injection pain: comparison of a modified propofol emulsion to standard propofol with premixed lidocaine. ( Adam, S; Dirckx, M; Jonsson, D; Klein, J; Pelka, M; van Bommel, J, 2004) |
| "To evaluate the efficacy of lidocaine tape in reducing pain during botulinum toxin injection." | 9.11 | Lidocaine tape (Penles) reduces the pain of botulinum toxin injection for Meige syndrome. ( Dogru, M; Onguchi, T; Ono, M; Takano, Y; Tsubota, K, 2004) |
| "A common drawback of propofol is pain on injection and lidocaine is commonly mixed with propofol to reduce its incidence and severity." | 9.11 | Comparison of Propofol-Lipuro with propofol mixed with lidocaine 10 mg on propofol injection pain. ( Abdul-Latif, MS; Kam, E; McCluskey, A, 2004) |
| "The incidence of pain on injection of propofol has been reported to be 70%." | 9.11 | Pain on injection: a double-blind comparison of propofol with lidocaine pretreatment versus propofol formulated with long- and medium-chain triglycerides. ( Kern, C; Landau, R; Schaub, E, 2004) |
| "To determine the impact of the lidocaine patch 5% on distinct pain qualities associated with osteoarthritis (OA) through use of the Neuropathic Pain Scale (NPS), an assessment tool designed to assess intensity of various pain qualities (i." | 9.11 | Lidocaine patch 5% and its positive impact on pain qualities in osteoarthritis: results of a pilot 2-week, open-label study using the Neuropathic Pain Scale. ( Argoff, CE; Galer, BS; Gammaitoni, AR; Jensen, MP; Onawola, R, 2004) |
| "To determine the effectiveness of lidocaine-adrenaline-tetracaine (LAT) in providing adequate anesthesia for the repair of finger lacerations and to monitor the risk of digital ischemia following application of LAT gel to finger lacerations." | 9.11 | The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations. ( Bergholte, J; Brousseau, DC; Hennes, H; Kim, MK; White, NJ, 2004) |
| "A randomized double-blind study compared two methods of preventing the pain from injection of propofol, lignocaine pre-treatment followed by propofol and lignocaine added to propofol." | 9.11 | Preventing pain on injection of propofol: a comparison between lignocaine pre-treatment and lignocaine added to propofol. ( Lee, P; Russell, WJ, 2004) |
| ") ketamine sedation administered by nonanesthetist physicians for painful procedures." | 9.11 | Intravenous ketamine sedation for painful oncology procedures. ( Barbour, K; Evans, D; Kobe, J; Montgomery, CJ; Rogers, P; Turnham, L; Vandebeek, C; Wilson, L, 2005) |
| " We studied its efficacy in decreasing the pain associated with IV administration of propofol and compared it with mixing lidocaine with propofol." | 9.11 | Bacteriostatic saline containing benzyl alcohol decreases the pain associated with the injection of propofol. ( Minogue, SC; Sun, DA, 2005) |
| "To compare the pain induced by outpatient flexible cystoscopy in men having local lidocaine jelly application or plain lubricant." | 9.11 | Randomized double-blind comparison of lidocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy. ( Chen, YT; Hsiao, PJ; Hsieh, CH; Wang, CC; Wong, WY; Yang, SS, 2005) |
| "Twenty-four spinal cord injury patients with neuropathic pain at or below the level of injury were randomized and completed a double-blind crossover trial of 5 mg/kg lidocaine and placebo infused over 30 min." | 9.11 | Intravenous lidocaine relieves spinal cord injury pain: a randomized controlled trial. ( Bach, FW; Biering-Sørensen, F; Finnerup, NB; Jensen, TS; Johannesen, IL; Juhl, GI; Kristensen, AD; Sindrup, SH; Terkelsen, AJ, 2005) |
| "To compare the efficacy of topical eutectic mixture of local anesthetics (EMLA) versus topical lidocaine (LMX) in pain control for Nd:YAG 1,064 nm laser hair removal." | 9.11 | Direct comparison of EMLA versus lidocaine for pain control in Nd:YAG 1,064 nm laser hair removal. ( Guardiano, RA; Norwood, CW, 2005) |
| "25 patients (83%) complained of pain in the placebo group, compared with 12 (40%) in the lidocaine group (P < 0." | 9.11 | A lidocaine/metoclopramide combination decreases pain on injection of propofol. ( Fujii, Y; Nakayama, M, 2005) |
| " lidocaine and nitrous oxide (N2O) in oxygen (O2) inhalation pre-treatment was compared with either treatment alone in the prevention of pain on propofol injection." | 9.11 | A combination of lidocaine and nitrous oxide in oxygen is more effective in preventing pain on propofol injection than either treatment alone. ( Elsaigh, I; Galvin, E; Harmon, D; Leonard, I; Niazi, A; Wahid, Z, 2005) |
| "A new MCT-LCT propofol formulation as a plain solution was associated with a higher incidence of injection pain than LCT propofol with added lidocaine when used for induction of anaesthesia in children." | 9.11 | Propofol injection pain in children: a prospective randomized double-blind trial of a new propofol formulation versus propofol with added lidocaine. ( Eksborg, S; Georgiadi, A; Lönnqvist, PA; Nyman, Y; von Hofsten, K, 2005) |
| "Propofol formulated in medium- and long-chain triglycerides (MCT/LCT) is thought to cause less pain on injection." | 9.11 | The effects of intravenous lidocaine on pain during injection of medium- and long-chain triglyceride propofol emulsions. ( Chong, SY; Goh, MH; Tan, KH; Yew, WS, 2005) |
| "In a randomized, double-blind, prospective trial we compared the efficacy of pre-treatment with nitrous oxide (with or without premixed lignocaine in propofol) for the prevention of propofol-induced pain." | 9.11 | Effect of nitrous oxide in reducing pain of propofol injection in adult patients. ( Neema, PK; Rathod, RC; Sinha, PK, 2005) |
| "Use of liposomal lidocaine was associated with a higher intravenous cannulation success rate, less pain, shorter total procedure time and minor dermal changes among children undergoing cannulation." | 9.11 | Liposomal lidocaine to improve procedural success rates and reduce procedural pain among children: a randomized controlled trial. ( Koren, G; Schuh, S; Scolnik, D; Soin, HK; Taddio, A, 2005) |
| "To compare intraoperative pain responses following intraovarian versus mesovarian injection of lidocaine in mares undergoing laparoscopic ovariectomy." | 9.11 | Intraoperative pain responses following intraovarian versus mesovarian injection of lidocaine in mares undergoing laparoscopic ovariectomy. ( Farstvedt, EG; Hendrickson, DA, 2005) |
| "5% are significantly more effective than 20% benzocaine in reducing pain from needle stick in the maxillary vestibular mucosa." | 9.11 | Reduction of pain from needle stick in the oral mucosa by topical anesthetics: a comparative study between lidocaine/prilocaine and benzocaine. ( Abu Al-Melh, M; Andersson, L; Behbehani, E, 2005) |
| "We conducted a randomized, double-blind, placebo-controlled trial comparing pain scores during bladder catheterization with 2% lidocaine gel versus nonanesthetic lubricant." | 9.11 | Does lidocaine gel alleviate the pain of bladder catheterization in young children? A randomized, controlled trial. ( Bush, A; Paton, EA; Pershad, J; Vaughan, M, 2005) |
| "The numbers of patients with severe and mild pain were larger in the order: LCT group (10 and 31 patients, respectively) > flurbiprofen 1 group (3 and 19) > or = MCT/LCT group (1 and 14) > or = lidocaine group (2 and 11) > flurbiprofen group (0 and 0)." | 9.11 | How to decrease pain at rapid injection of propofol: effectiveness of flurbiprofen. ( Nishiyama, T, 2005) |
| "Pain on injection, reported in 28-90% of patients, is one of the most described side effects of the intravenous application of propofol." | 9.11 | Comparison on pain on injection of a small particle size-lipid emulsion of propofol and standard propofol with or without lidocaine. ( Diregpoke, S; Krobbuaban, B; Kumkeaw, S; Tanomsat, M, 2005) |
| "Topical lidocaine-prilocaine (EMLA) effectively decreases the pain associated with minor procedures including immunization, although the effect on the antibody response to diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b conjugate (DTaP-IPV-Hib) and hepatitis B vaccines has not been assessed." | 9.10 | Use of lidocaine-prilocaine patch to decrease intramuscular injection pain does not adversely affect the antibody response to diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b conjugate and hepatitis B vaccines in ( Halperin, BA; Halperin, SA; Houston, T; McGrath, P; Smith, B, 2002) |
| "The use of intrarectal lidocaine is not superior to placebo during transrectal prostate biopsy for pain control." | 9.10 | Lack of effect of intrarectal lidocaine for pain control during transrectal prostate biopsy: a randomized prospective study. ( Akdaş, A; Cevik, I; Dillioglugil, O; Ozveri, H, 2002) |
| "To evaluate patients' perceptions and preferences concerning pain control during intravenous (IV) catheterization, a sample of 50 adult patients received subcutaneous lidocaine (0." | 9.10 | Subcutaneous lidocaine delivered by jet-injector for pain control before IV catheterization in the ED: the patients' perception and preference. ( Frasure, HE; Peter, DJ; Scott, JP; Watkins, HC, 2002) |
| "Although it is well-known that 2% lidocaine has an effective action for preventing propofol-induced pain, it has been unclear whether or not lidocaine of the concentration below 2% has the effective action similar to 2% lidocaine." | 9.10 | [Effects of concentration and dosage of lidocaine on preventing the pain on injection of propofol]. ( Adachi, H; Harada, T; Hirosawa, J; Inagaki, Y; Ishibe, Y; Otsuki, A; Tsubokura, H, 2002) |
| "We compared the ability of metoclopramide with IV lidocaine pretreatment to abolish pain from a diazepam injection." | 9.10 | A comparison of metoclopramide and lidocaine for preventing pain on injection of diazepam. ( Hassannasab, B; Khan, ZH; Majedi, H; Rabiee, M, 2002) |
| " Based on the clinical evidence of pain alleviation by topical morphine in patients with some inflammatory and painful conditions, a clinical study was undertaken to determine this effect on mucositis-associated pain." | 9.10 | Effect of topical morphine for mucositis-associated pain following concomitant chemoradiotherapy for head and neck carcinoma. ( Bonomi, MR; Cerchietti, LC; Menéndez, PR; Navigante, AH; Pogany, CE; Roth, BM; Zaderajko, MA, 2002) |
| "We conducted a randomized, double blinded, placebo controlled trial to evaluate the effectiveness of EMLA cream together with intraperitoneal lidocaine for pain relief in postpartum tubal ligation." | 9.10 | EMLA cream and intraperitoneal lidocaine decrease intraoperative pain during postpartum tubal sterilization. ( Apidechakul, P; Ariyanon, P; Latthikaviboon, U; Limsakul, A; Parakkamodom, S; Permpolprasert, L; Pethpaisit, N; Santivarangkana, T; Sirilertmakasakul, P; Visalyaputra, S, 2002) |
| "To estimate the efficacy of lidocaine ointment in relieving pain after a vaginal delivery with an episiotomy or perineal laceration." | 9.10 | Randomized trial of lidocaine ointment versus placebo for the treatment of postpartum perineal pain. ( Jazayeri, A; Minassian, VA; Prien, SD; Stumbo, K; Timmons, RL, 2002) |
| "To investigate if 50% nitrous oxide reduces the pain during injection of propofol mixed with lidocaine in children." | 9.10 | In children, nitrous oxide decreases pain on injection of propofol mixed with lidocaine. ( Beh, T; Kim, J; Splinter, W, 2002) |
| "When compared with rocuronium alone, only the addition of saline failed to significantly reduce the pain reported by patients." | 9.10 | Comparison of four strategies to reduce the pain associated with intravenous administration of rocuronium. ( Chiarella, AB; Clanachan, AS; Huston, CM; Jolly, DT, 2003) |
| " Without analgesia (control) 26 of 45 patients (58%) reported pain on injection compared with 11 of 45 patients (24%) in both the nitrous oxide (95% CI: 14-52%, P = 0." | 9.10 | Nitrous oxide/oxygen mixture and the prevention of pain during injection of propofol. ( Harmon, D; Lowe, D; Rozario, C, 2003) |
| "25 microg x kg(-1) x min(-1) with 40 mg lidocaine and placebo in the prevention of injection pain due to intravenous propofol administration (1." | 9.10 | Prevention of propofol-induced injection pain by remifentanil: a placebo-controlled comparison with lidocaine. ( Boldt, J; Maleck, WH; Piper, SN; Roehm, KD, 2003) |
| "Pain is often experienced when propofol is injected, and intravenous lidocaine is often effective in preventing such pain." | 9.10 | Pain on injection of propofol: comparison of metoprolol with lidocaine. ( Aşik, I; Gülay, I; Tulunay, M; Yörükoğlu, D, 2003) |
| "In terms of pain control, lidocaine 2% gel alone is a superior topical anesthetic for one-stage adjustable suture strabismus surgery when compared with amethocaine 1% eyedrops." | 9.10 | Comparison of lidocaine 2% gel versus amethocaine as the sole anesthetic agent for strabismus surgery. ( Fan, DS; Lam, DS; Wong, VW; Yip, WW; Yu, CB, 2003) |
| "We compared the efficacy of magnesium sulphate, lignocaine, sodium bicarbonate or alfentanil in minimizing pain due to injection of rocuronium in 250 patients." | 9.10 | The prevention of pain from injection of rocuronium by magnesium sulphate, lignocaine, sodium bicarbonate and alfentanil. ( Karamanlioglu, B; Memis, D; Pamukcu, Z; Sut, N; Turan, A, 2003) |
| "The authors conducted this study to compare the pain on injection of the three mandibular block techniques and to determine the effect that the delivery of nitrous oxide:oxygen, or N2O:O2, had on this pain." | 9.10 | Injection pain: comparison of three mandibular block techniques and modulation by nitrous oxide:oxygen. ( Haas, DA; Jacobs, S; May, S; Meechan, JG, 2003) |
| "Topical anesthesia using 60% lidocaine tape reduces the incidence of propofol injection pain." | 9.10 | The efficacy of 5% lidocaine-prilocaine (EMLA) cream on pain during intravenous injection of propofol. ( Currer, BA; McCluskey, A; Sayeed, I, 2003) |
| "Pain scores with piroxicam gel were higher on cannulation and on advancement of the cannula (P < 0." | 9.10 | Piroxicam gel, compared to EMLA cream is associated with less pain after venous cannulation in volunteers. ( Dutta, A; Puri, GD; Wig, J, 2003) |
| "The incidence of pain of the infusion was significantly lower in patients pretreated with ketamine (8% vs 37%, P = 0." | 9.10 | Pretreatment with intravenous ketamine reduces propofol injection pain. ( Barbi, E; Gagliardo, A; Gerarduzzi, T; Marchetti, F; Neri, E; Sarti, A; Ventura, A, 2003) |
| "To assess the effectiveness and safety of the lidocaine patch 5%, a targeted peripheral analgesic, in the treatment of postherpetic neuralgia, painful diabetic neuropathy, and low back pain patients with incomplete responses to their current analgesic treatment regimen containing gabapentin." | 9.10 | Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain. ( Drass, M; Nalamachu, S; Patel, N; White, WT, 2003) |
| "Using 2-chloroprocaine can diminish pain caused by the intradermal injection of lidocaine." | 9.10 | Chloroprocaine is less painful than lidocaine for skin infiltration anesthesia. ( Janosky, JE; Marica, LS; Nystrom, EU; O'Day, T, 2002) |
| "We compared the efficacy of ondansetron, lidocaine, tramadol, and fentanyl in minimizing pain caused by the injection of rocuronium in 250 patients." | 9.10 | The prevention of pain from injection of rocuronium by ondansetron, lidocaine, tramadol, and fentanyl. ( Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Süt, N; Turan, A, 2002) |
| "To compare the effects of nitrous oxide with lidocaine on pain on injection caused by propofol in children." | 9.10 | [Prevention of pain on injection with propofol in children: comparison of nitrous oxide with lidocaine]. ( Ecoffey, C; Geslot, D; Lembert, N; Wodey, E, 2002) |
| "A double-randomized, blinded crossover trial was performed to assess the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics (EMLA) for pain relief during pediatric venipuncture procedures." | 9.10 | A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children. ( Cunningham, BB; Eichenfield, LF; Fallon-Friedlander, S; Funk, A, 2002) |
| "The iontophoretic application of lidocaine was compared with intravenous lidocaine to assess the relative efficacy of reducing pain during propofol administration." | 9.10 | Iontophoretically applied lidocaine and the prevention of pain associated with the injection of intravenous propofol: a comparison with intravenous lidocaine. ( Asif, M; Rowbotham, DJ; Sharpe, P; Victoria, A, 2002) |
| " retention of metoclopramide with tourniquet is as good as lidocaine and may be a useful alternative for reducing pain on propofol injection." | 9.09 | Pain on injection of propofol: the mitigating influence of metoclopramide using different techniques. ( Chang, DP; Hwang, MH; Liaw, WJ; Pang, WW, 1999) |
| "Nine patients with Complex Regional Pain Syndrome types I and/or II (CRPS), previously known as reflex sympathetic dystrophy (RSD) and causalgia, respectively, were selected for treatment with a continuous four to eight week subcutaneous infusion of 10% lidocaine." | 9.09 | Subcutaneous infusion of lidocaine provides effective pain relief for CRPS patients. ( Linchitz, RM; Raheb, JC, 1999) |
| "We conducted a randomized, double-blinded, placebo-controlled trial to evaluate the effectiveness of intraperitoneal lidocaine, IM morphine, or both drugs together for pain relief in postpartum tubal ligation." | 9.09 | Intraperitoneal lidocaine decreases intraoperative pain during postpartum tubal ligation. ( Lertakyamanee, J; Parakkamodom, S; Pethpaisit, N; Somprakit, P; Suwanapeum, P; Visalyaputra, S, 1999) |
| "To compare efficacy and cost of lidocaine cutaneous anesthesia by two jet injectors to routine needle infiltration for pain relief of intravenous (i." | 9.09 | Painless intravenous catheterization by intradermal jet injection of lidocaine: a randomized trial. ( Darby, P; Goll, EF; Koenig, HM; Zsigmond, EK, 1999) |
| "This study investigated the effect of intravenous lidocaine at two doses (1 mg/kg and 5 mg/kg over 2 hours) and an intravenous saline placebo on the pain and allodynia of postherpetic neuralgia (PHN)." | 9.09 | A trial of intravenous lidocaine on the pain and allodynia of postherpetic neuralgia. ( Baranowski, AP; Bonello, E; De Courcey, J, 1999) |
| "We have compared iontophoretically and locally applied lidocaine for relief of pain on propofol injection." | 9.09 | Iontophoretically applied lidocaine reduces pain on propofol injection. ( Liddle, A; Maslowski, P; Rowbotham, DJ; Sadler, PJ; Thompson, HM, 1999) |
| "To determine the optimal concentration of lidocaine that reduces pain on injection of a propofol-lidocaine mixture." | 9.09 | The optimal effective concentration of lidocaine to reduce pain on injection of propofol. ( Chu, CC; Ho, CM; Lee, TY; Sun, MS; Tsou, MY, 1999) |
| "The purpose of this study was to compare the effect of premixed 5% dextrose in Ringer's acetate solution and premixed lidocaine with propofpl on the reduction of pain during injection of propofol in adult patients." | 9.09 | [Premixing of 5% dextrose in Ringer's acetate solution with propofol reduces incidence and severity of pain on propofol injection]. ( Kashimoto, S; Kumazawa, T; Nonaka, A; Oguchi, T; Sugawara, T; Tamaki, F, 1999) |
| " The pain which occurs as a response to an intravenous injection of Propofol is one of the main obstacles to its use as an anesthetic." | 9.09 | [Administration of propofol. Addition of lidocaine eases the pain]. ( Fernández, V; Hernández, S; López, S; Santamaría, R, 1999) |
| "Intravenous lidocaine and diphenhydramine had no significant effect on the cool, warm, or cold pain thresholds." | 9.09 | Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II. ( Gerayli, A; Leung, AY; Ridgeway, BM; Wallace, MS; Yaksh, TL, 2000) |
| "To elucidate the mechanism of propofol-induced pain on injection, we performed several studies using nafamostat mesilate, a kallikrein inhibitor, or lidocaine." | 9.09 | A potential mechanism of propofol-induced pain on injection based on studies using nafamostat mesilate. ( Iwama, H; Nakane, M, 1999) |
| "To investigate the effects of systemic administration of lidocaine on different components of neuropathic central pains by quantitative sensory testing." | 9.09 | Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study. ( Attal, N; Bouhassira, D; Brasseur, L; Dupuy, M; Gaudé, V; Guirimand, F; Parker, F, 2000) |
| "A prospective, randomized, double-blind study was conducted to determine whether cooled intravenous propofol reduces the incidence of pain on induction of anaesthesia in children." | 9.09 | Propofol and pain on induction: the effect of injectate temperature in children. ( Burden, J; Lewis, I; Pickford, A, 2000) |
| "We have assessed the incidence of pain on injection of rocuronium and evaluated if pretreatment with lidocaine i." | 9.09 | Pain on injection of rocuronium: influence of two doses of lidocaine pretreatment. ( Cheong, KF; Wong, WH, 2000) |
| "This investigation evaluated the use and efficacy of prilocaine HCl (4% plain Citanest) for minimizing pain associated with the intraoral administration of local anesthesia." | 9.09 | Evaluation of prilocaine for the reduction of pain associated with transmucosal anesthetic administration. ( Eleazer, PD; Kramp, LF; Scheetz, JP, 1999) |
| "Although effective in neuropathic pain, the efficacy of systemic lidocaine in non-neuropathic pain remains uncertain." | 9.09 | The effect of systemic lidocaine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers. ( Dahl, JB; Dirks, J; Fabricius, P; Petersen, KL; Rowbotham, MC, 2000) |
| "A mixture of 40 mg of triamcinolone acetonide and 1 ml of 2 percent lidocaine was injected into the tenderest point transanally in 104 patients (33 males; mean age, 51 years) with levator syndrome from December 1996 to May 1998 at Daehang Clinic." | 9.09 | Transanally injected triamcinolone acetonide in levator syndrome. ( Cho, HJ; Jeong, SY; Kang, YS; Kim, DS; Kim, TS; Lee, DH, 2000) |
| "Our goal was to perform a pilot study to assess the effectiveness and tolerability of a topical lidocaine patch (Lidoderm) for the treatment of peripheral neuropathic pain conditions other than postherpetic neuralgia." | 9.09 | Topical lidocaine patch relieves a variety of neuropathic pain conditions: an open-label study. ( Devers, A; Galer, BS, 2000) |
| "There was minimal change in the degree of pain in the lidocaine-only and control groups during and after the treatment period." | 9.09 | Intrathecal methylprednisolone for intractable postherpetic neuralgia. ( Asai, M; Hashimoto, H; Kimura, F; Kotani, N; Kushikata, T; Matsuki, A; Muraoka, M; Yodono, M, 2000) |
| "Analgesic efficacy of repeated application of a lidocaine cream formula was investigated in herpes zoster patients with subacute pain with no further improvement after continued treatment since their acute stage (S-HZ group, n = 23), and in patients to whom past treatments had not provided adequate pain relief (PHN group, n = 28)." | 9.09 | [Relief of subacute herpetic pain and postherpetic neuralgia with repeated application of 10% lidocaine cream]. ( Iseki, M; Mitsuhata, H; Miyazaki, T; Toriumi, E; Yoshino, K, 2000) |
| "The purpose of this study was to compare the younger and older patients in the incidence and the severity of the pain during injection of propofol." | 9.09 | [Effect of pre-mixed lidocaine with propofol on propofol injection pain in elderly patients]. ( Kumazawa, T; Nonaka, A; Suzuki, M; Suzuki, S; Tamaki, F, 2000) |
| "To compare the relative efficacy of oral sucrose versus EMLA cream for pain relief during venepuncture, 51 full-term newborns (38M, 13F; postnatal age <4 d) in a stable condition were randomly allocated to one of four treatment groups: placebo (2 ml spring water); 2 ml sucrose 24% w/v; 1 g lidocaine-prilocaine 5% cream (EMLA); or EMLA plus sucrose." | 9.09 | Oral sucrose compares favourably with lidocaine-prilocaine cream for pain relief during venepuncture in neonates. ( Abad, F; Díaz-Gómez, NM; Domenech, E; Feria, M; González, D; Robayna, M, 2001) |
| "To determine whether epidural lidocaine reduces the severity of propofol injection pain compared with iv lidocaine." | 9.09 | Epidural anesthesia with lidocaine reduces propofol injection pain. ( Inoue, T; Ogawa, R; Ogura, A; Wajima, Z; Yoshikawa, T, 2001) |
| "Propofol is frequently associated with pain on injection." | 9.09 | Role of tramadol in reducing pain on propofol injection. ( Cheong, KF; Wong, WH, 2001) |
| "In a randomised, controlled, double-blinded trial to study the effect of ondansetron pretreatment on the pain produced after intravenous injection of rocuronium and propofol in comparison with lidocaine, 60 patients were randomly assigned to one of three groups." | 9.09 | Effect of ondansetron pretreatment on pain after rocuronium and propofol injection: a randomised, double-blind controlled comparison with lidocaine. ( Chen, FG; Ng, HP; Reddy, MS, 2001) |
| "To compare the efficiency of lidocaine with that of plain saline for paracervical pain relief during fractional curettage." | 9.09 | Lidocaine versus plain saline for pain relief in fractional curettage: a randomized controlled trial. ( Chanrachakul, B; Herabutya, Y; Likittanasombut, P; O-Prasertsawat, P, 2001) |
| "To evaluate differences in pain, photophobia, retinal and optic nerve function in test eyes given intracameral lidocaine compared with control eyes given intracameral saline after phacoemulsification under topical anesthesia." | 9.09 | Pain, photophobia, and retinal and optic nerve function after phacoemulsification with intracameral lidocaine. ( Fujimoto, DK; Pang, MP; Wilkens, LR, 2001) |
| "To investigate the effect of simultaneous bolus injection of 2% lidocaine 2 ml on preventing the pain on propofol injection, 80 patients were randomly assigned to one of four study groups; Group I received simultaneous bolus injection of 2% lidocaine 2 ml with infusion of propofol; Group II received bolus injection of saline 2 ml, 10 s before the start of infusion of propofol-lidocaine mixture; Groups III and IV received bolus injections of lidocaine and saline, separately 10 s before starting propofol infusion." | 9.09 | [Efficacy of simultaneous bolus injection of lidocaine with propofol on pain caused by propofol injection]. ( Adachi, H; Harada, T; Hirosawa, J; Inagaki, Y; Ishibe, Y; Otsuki, A; Tsubokura, H, 2001) |
| "To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes." | 9.08 | The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial. ( Delaney, G; Heck, C; Janzen, V; McCain, GA; Russell, AL; Scudds, RA; Teasell, RW; Varkey, G; Woodbury, GM, 1995) |
| "To determine whether topical lidocaine attenuates the pain of buffered lidocaine infiltration." | 9.08 | Does topical lidocaine attenuate the pain of infiltration of buffered lidocaine? ( Bartfield, JM; Raccio-Robak, N; Salluzzo, RF, 1995) |
| " Buffering lidocaine with sodium bicarbonate significantly reduced pain scores reported by 46 women who participated in this randomized, double-blind study." | 9.08 | Neutralizing pH of lidocaine reduces pain during Norplant system insertion procedure. ( Nelson, AL, 1995) |
| "Lidocaine 1% can be safely and usefully combined with intracorporeal prostaglandin E1 in the treatment of erectile dysfunction with alleviation of pain and enhancement of erectile effect." | 9.08 | Double-blind randomized crossover study comparing intracorporeal prostaglandin E1 with combination of prostaglandin E1 and lidocaine in the treatment of organic impotence. ( Kattan, S, 1995) |
| "Propofol, which is commonly used for outpatient anaesthesia, may evoke pain during infusion." | 9.08 | Prilocaine reduces injection pain caused by propofol. ( Eriksson, M, 1995) |
| " Our aim was to compare EMLA and placebo to assess the efficacy of EMLA in decreasing the pain of venipuncture in children premedicated with oral midazolam 0." | 9.08 | [Efficacy of the EMLA cream in the reduction of pain caused by venipuncture in children premedicated with oral midazolam]. ( Cassinello, F; de Stefano, J; Herrero, E; Martín-Celemín, R; Palencia, J; Pérez-Gallardo, A, 1995) |
| "This study investigated propofol injection pain in patients undergoing ambulatory anaesthesia." | 9.08 | Thiopentone pretreatment for propofol injection pain in ambulatory patients. ( Haugen, RD; Merrick, PM; Vaghadia, H; Waters, T, 1995) |
| "Pain intensity, muscle strength, static muscle endurance, pressure pain threshold, and pain tolerance at tender points and control points were assessed in 31 patients with fibromyalgia (FM), before and after intravenous administration of morphine (9 patients), lidocaine (11 patients), and ketamine (11 patients)." | 9.08 | Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine. ( Bäckman, E; Bengtsson, A; Bengtsson, M; Henriksson, KG; Sörensen, J, 1995) |
| "We undertook a randomized, placebo-controlled, double-blind study to compare the use of alfentanil 1 mg and lidocaine 40 mg for the reduction of pain during injection of propofol." | 9.08 | Prevention of pain on injection of propofol: a comparison of lidocaine with alfentanil. ( Gajraj, NM; Nathanson, MH; Russell, JA, 1996) |
| "9% saline (1 ml) on a double-blind basis, as pretreatment to reduce pain on injection of propofol." | 9.08 | Modification of pain on injection of propofol. A comparison of pethidine and lignocaine. ( Flynn, C; Lohan, D; Lyons, B; McCarroll, M, 1996) |
| "This study was performed in order to determine concentration-effect, and graded and quantal dose-response relationships for the clinical administration of intravenous (IV) lidocaine to patients with neuropathic pain." | 9.08 | The analgesic response to intravenous lidocaine in the treatment of neuropathic pain. ( Arthur, GR; Cherukuri, S; Ferrante, FM; Paggioli, J, 1996) |
| "Twenty patients with chronic pain who previously had obtained analgesia from epidural clonidine and lignocaine agreed to participate in a double-blind crossover study of lumbar epidural clonidine (150 micrograms), lignocaine (40 mg) and the combination of clonidine (150 microgram) and lignocaine (40 mg), all drugs were given in a volume of 3 ml." | 9.08 | A double-blind randomised comparison of the effects of epidural clonidine, lignocaine and the combination of clonidine and lignocaine in patients with chronic pain. ( Glynn, C; O'Sullivan, K, 1996) |
| "We evaluated the effect of lidocaine containing adhesive tape (LT) on the venipuncture pain by using visual analogue scale (VAS)." | 9.08 | [Skillfulness is essential to improve venipuncture pain in combination with lidocaine containing adhesive tape]. ( Nakao, M; Onji, I, 1996) |
| " Eleven patients suffering from neuropathic pain after peripheral nerve injury received both a lidocaine and saline infusion in separate study sessions." | 9.08 | Computer-controlled lidocaine infusion for the evaluation of neuropathic pain after peripheral nerve injury. ( Dyck, BJ; Rossi, SS; Wallace, MS; Yaksh, TL, 1996) |
| "A randomised, controlled, single-blind study was performed on 100 patients to investigate a new method of reducing pain on propofol injection." | 9.08 | Injection pain with propofol. Reduction with aspiration of blood. ( Jameson, P; McDonald, DS, 1996) |
| "A randomised, double-blind, controlled trial was undertaken to compare three different methods of reducing pain during the intravenous injection of propofol." | 9.08 | The effect of pretreatment with ketorolac on pain during intravenous injection of propofol. ( Power, I; Smith, AJ, 1996) |
| "To define the optimal dose of lidocaine to be added to propofol to reduce the incidence of pain during its injection." | 9.08 | Preventing pain during injection of propofol: the optimal dose of lidocaine. ( Gajraj, NM; Nathanson, MH, 1996) |
| "To determine whether topical tetracaine attenuates the pain of buffered lidocaine infiltration." | 9.08 | Topical tetracaine attenuates the pain of infiltration of buffered lidocaine. ( Asher, SL; Bartfield, JM; Lee, FS; Raccio-Robak, N; Salluzzo, RF, 1996) |
| "There is no clear evidence that intraurethral lidocaine jelly decreases pain and/or makes rigid cystoscopy more tolerable for patients." | 9.08 | Randomized, prospective, double-blind study of the effects on pain perception of lidocaine jelly versus plain lubricant during outpatient rigid cystoscopy. ( Cromie, WJ; Gerber, GS; Goldfischer, ER; Karrison, TG; Naszkiewicz, L, 1997) |
| "To compare the local efficacy of lidocaine and fentanyl in reducing propofol injection pain (PIP), we conducted a prospective randomized double-blind study in 75 ASA I and II adult patients." | 9.08 | Reduction of propofol pain--fentanyl vs lidocaine. ( Alyafi, WA; Rangasami, J, 1996) |
| "To evaluate the effect of buffered lidocaine with self reporting of pain elicited during maxillary labial and palatal infiltrations of permanent canines." | 9.08 | Pain elicited during intraoral infiltration with buffered lidocaine. ( Primosch, RE; Robinson, L, 1996) |
| "The efficacy of tetracaine cream versus that of lidocaine-prilocaine cream for the prevention of pain in children undergoing venipuncture was studied." | 9.08 | Tetracaine versus lidocaine-prilocaine for preventing venipuncture-induced pain in children. ( Egberts, AC; Lenderink, AW; Rijnvos, WP; ter Pelkwijk, NJ; van Kan, HJ, 1997) |
| "To investigate the efficacy of lidocaine tape, a new preparation of lidocaine for cutaneous topical anaesthesia in the form of a self-adhesive tape, in alleviating the pain of needle insertion during stellate ganglion block." | 9.08 | Lidocaine tape relieves pain due to needle insertion during stellate ganglion block. ( Inada, K; Inada, T; Kawachi, S; Uesugi, F, 1997) |
| ") lidocaine and topical nitroglycerin ointment in preventing pain during propofol injection." | 9.08 | Effects of topical nitroglycerin and intravenous lidocaine on propofol-induced pain on injection. ( Beven, M; Carpenter, T; Laseter, JT; Mascha, E; Maurer, WG; O'Hara, JR; Sprung, J, 1997) |
| "Lidocaine-prilocaine cream is efficacious and safe for the prevention of pain from circumcision in neonates." | 9.08 | Efficacy and safety of lidocaine-prilocaine cream for pain during circumcision. ( Ben-David, S; Craig, K; Koren, G; Mulligan, P; Rastogi, P; Shennan, A; Stevens, B; Taddio, A, 1997) |
| "The purpose of this study was to confirm the effect of premixed lidocaine for the reduction of pain during injection of propofol in adult patients." | 9.08 | [Premixing lidocaine reduces the incidence and severity of pain on injection of propofol]. ( Akazawa, S; Fukuda, H; Inoue, S; Kasuda, H; Kawakami, T; Konishi, R; Mitsuhata, H; Saitoh, J; Saitoh, K; Shimizu, R; Suzuki, H, 1997) |
| "Pain is a well known complication of propofol injection." | 9.08 | [Effect of lidocaine administration mode on decreasing injection pain caused by propofol]. ( Bornscheuer, A; Goldmann, R; Kirchner, E, 1997) |
| "Propofol has the disadvantage of pain on injection." | 9.08 | Effect of lignocaine and pH on propofol-induced pain. ( Englesson, S; Eriksson, M; Hartvig, P; Niklasson, F, 1997) |
| "We determined whether pretreatment with topical 60% lidocaine tape reduced the incidence of pain on injection of propofol compared with mixing intravenous lidocaine with propofol." | 9.08 | Pretreatment with topical 60% lidocaine tape reduces pain on injection of propofol. ( Hosoda, R; Kimura, T; Komatsu, T; Komura, Y; Nishiwaki, K; Shimada, Y; Yokota, S, 1997) |
| "Intraoral lidocaine patches have recently been approved by the US Food and Drug Administration for the production of topical anesthesia before superficial dental procedures and for the reduction of pain associated with local anesthetic injections." | 9.08 | An evaluation of intraoral lidocaine patches in reducing needle-insertion pain. ( Heins, P; Houpt, MI; Lamster, I; Stone, C; Wolff, MS, 1997) |
| "Despite current clinical practice, there is no objective evidence to demonstrate the efficacy or pain on injection when hyaluronidase is added to lidocaine as an anesthetic combination for local anesthesia." | 9.08 | The effects of hyaluronidase on the efficacy and on the pain of administration of 1% lidocaine. ( Nevarre, DR; Tzarnas, CD, 1998) |
| "Propofol is frequently associated with pain on injection." | 9.08 | Pain on injection of propofol. A comparison of cold propofol with propofol premixed with lignocaine. ( Koay, CK; Parmar, AK, 1998) |
| ") retention of fentanyl and lidocaine in reducing the pain on i." | 9.08 | Comparison of intravenous retention of fentanyl and lidocaine on local analgesia in propofol injection pain. ( Chang, DP; Chung, YT; Hong, MH; Huang, S; Lin, SS; Pang, WW, 1997) |
| "To evaluate five different preoperative anxiolytic regimens in cataract surgery performed under regional anesthesia; to quantify the pain associated with combined peri- and retrobulbar injection (PRBI) of local anesthetic drugs; and to describe a technique of painless eye block." | 9.08 | Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery. ( Berry, RA; Boezaart, AP; Laubscher, JJ; Nell, ML, 1998) |
| "To evaluate the efficacy of continuous administration of 50% nitrous oxide in oxygen for reducing pain during flexible fiberoptic bronchoscopy 32 children aged 3-60 months were randomly assigned to an experimental or a control group." | 9.08 | [Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination]. ( Dupont, D; Garcia, J; Hayem, C; Roure, P, 1998) |
| "This study compared the pain from intradermal infiltration of (1) plain lidocaine, (2) warmed lidocaine, (3) buffered lidocaine, and (4) warmed, buffered lidocaine." | 9.08 | Pain reduction in lidocaine administration through buffering and warming. ( Colaric, KB; Moore, K; Overton, DT, 1998) |
| "Pain on injection is one of the well-known side effects of propofol." | 9.08 | [Pain-free injection of propofol]. ( Ichimiya, T; Kamada, Y; Kobayashi, Y; Kumagai, A; Namiki, A; Seki, S; Tsuchida, H, 1998) |
| "We evaluated the efficacy of the 60% lidocaine tape in alleviating pain associated with intravenous propofol administration in 71 gynecological patients." | 9.08 | [Sixty percent lidocaine tape alleviates pain on injection of propofol after diminishing venipuncture pain]. ( Akatsuka, M; Doi, Y; Inamori, K; Kunimasa, K; Minami, T; Mori, H; Ohnaka, M; Ohtsuka, M; Uda, R, 1998) |
| "We compared the effect of fentanyl and lidocaine on pain during injection of propofol." | 9.08 | [Reduction of pain on injection of propofol: a comparison of fentanyl with lidocaine]. ( Aketa, K; Ichimiya, T; Kobayashi, Y; Naganuma, R; Namiki, A; Seki, S, 1998) |
| "The purpose of the present study is to compare the injection pain of propofol with that of benzodiazepines when used for intravenous sedation." | 9.08 | Pain following intravenous administration of sedative agents: a comparison of propofol with three benzodiazepines. ( Fukuda, K; Ichinohe, T; Kaneko, Y; Kasahara, M; Mamiya, H; Noma, T, 1998) |
| "9% sodium chloride containing the preservative benzyl alcohol with lidocaine hydrochloride 1% as an intradermal pretreatment for the relief of pain associated with intravenous cannulation." | 9.08 | Intradermal bacteriostatic 0.9% sodium chloride containing the preservative benzyl alcohol compared with intradermal lidocaine hydrochloride 1% for attenuation of intravenous cannulation pain. ( McNelis, KA, 1998) |
| "To investigate the effects of warming vs buffering, and warming with buffering, on the pain of lidocaine infiltration." | 9.08 | The effects of warming and buffering on pain of infiltration of lidocaine. ( Bartfield, JM; Crisafulli, KM; Raccio-Robak, N; Salluzzo, RF, 1995) |
| "Lignocaine has been shown to reduce the incidence of pain on injection of propofol." | 9.07 | Propofol injection pain: comparing the addition of lignocaine or metoclopramide. ( Mecklem, DW, 1994) |
| "A prospective, randomised, double-masked, placebo-controlled study was carried out on 169 patients undergoing cataract extraction to compare the topical anaesthetic cream amethocaine with EMLA (eutetic mixture of local anaesthetic, lignocaine and prilocaine) and placebo in reducing pain during retrobulbar injection." | 9.07 | A comparison of amethocaine cream with lignocaine-prilocaine cream (EMLA) for reducing pain during retrobulbar injection. ( Joyce, PW; Kirby, J; Sunderraj, P; Villada, J; Watson, A, 1994) |
| "Benzyl alcohol is reported to be painless on injection and to provide limited dermal anesthesia." | 9.07 | Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia. ( Howe, NR; Williams, JM, 1994) |
| "A controlled, double-blind study was performed to compare the prior administration of intravenous saline 4 ml (n = 36), lignocaine 20 mg (n = 36) or thiopentone 100 mg (n = 43) on the pain produced by intravenous injection of propofol." | 9.07 | Pain during injection of propofol. The effect of prior administration of thiopentone. ( Lee, TW; Loewenthal, AE; Strachan, JA; Todd, BD, 1994) |
| "A randomized double-blind study was made of 60 children aged 5 to 11 years to assess the efficacy of a eutectic mixture of local anaesthetics (EMLA), lidocaine and prilocaine, and placebo cream in reducing venepuncture pain." | 9.07 | Placebo effect of eutectic mixture of lidocaine and prilocaine (EMLA) cream in reducing venepuncture pain in children. ( Lurngnateetape, A; Tritrakarn, T, 1994) |
| "5% bupivacaine, and 2% lidocaine for pain of injection and duration of anesthesia." | 9.07 | Pain of injection and duration of anesthesia for intradermal infiltration of lidocaine, bupivacaine, and etidocaine. ( Howe, NR; Williams, JM, 1994) |
| "A controlled randomized double-blinded clinical study was undertaken to evaluate and compare the efficacy of three methods of preventing pain during injection of propofol on induction of anesthesia." | 9.07 | Pain on injection of propofol. ( Chen, GT; Chen, TY; Hwang, MH; Lin, JC; Lin, SS, 1994) |
| "To compare the pain associated with ceftriaxone sodium injections by using two different diluents, ie, lidocaine hydrochloride and sterile water." | 9.07 | Lidocaine as a diluent for ceftriaxone in the treatment of gonorrhea. Does it reduce the pain of the injection? ( Bernstein, B; Fitzgerald, J; Schechter, N; Schichor, A; Weinerman, H; Yordan, E, 1994) |
| "To determine whether use of lidocaine-prilocaine 5% cream (EMLA) decreases pain associated with diphtheria-pertussis-tetanus (DPT) vaccination in infants." | 9.07 | Use of lidocaine-prilocaine cream for vaccination pain in infants. ( Goldbach, M; Ipp, M; Koren, G; Nulman, I; Taddio, A, 1994) |
| "A double-blind study was set up to investigate the effect of pretreatment with lignocaine on the incidence of potassium chloride infusion pain." | 9.07 | Efficacy of lignocaine in alleviating potassium chloride infusion pain. ( Khoo, ST; Kloo, ST; Lim, ET; Tweed, WA, 1992) |
| "We have conducted a randomized, double-blind study in 255 ASA I and II patients to compare the efficacy of lignocaine and metoclopramide in minimizing the pain of injection of i." | 9.07 | Pain on injection of propofol: comparison of lignocaine with metoclopramide. ( Fee, JP; Ganta, R, 1992) |
| "kg-1 on reducing injection pain caused by propofol was compared with lignocaine 10 mg mixed with propofol (Lign)." | 9.07 | Injection pain, cardiovascular changes and recovery following induction of anaesthesia with propofol in combination with alfentanil or lignocaine in children. ( Hiller, A; Saarnivaara, L, 1992) |
| "The clinical benefits of transdermal 10% lidocaine base gels with and without 3% glycyrrhetinic acid monohemiphthalate disodium (GAMHPh) for reduction of pain at venous cannulation were compared in a randomized, double-blind fashion in 24 surgical patients." | 9.07 | A comparative study of transdermal 10% lidocaine gel with and without glycyrrhetinic acid monohemiphthalate disodium for pain reduction at venous cannulation. ( Hashiguchi, A; Kano, T; Mishima, M; Morioka, T; Nakamura, M; Nakano, M, 1992) |
| "In a single-blind study of 100 children aged 1 to 10 years, the minimum effective dose of lignocaine required to prevent injection pain due to propofol was 0." | 9.07 | The minimum effective dose of lignocaine to prevent injection pain due to propofol in children. ( Cameron, E; Crofts, S; Johnston, G; Morton, NS, 1992) |
| "Propofol has a high incidence of pain with injection, particularly into small veins." | 9.07 | Lidocaine for the prevention of pain due to injection of propofol. ( Davis, FM; King, SY; Murchison, DJ; Pryor, PJ; Wells, JE, 1992) |
| "We evaluated the efficacy of intravenous lidocaine, with and without a tourniquet, to decrease the intensity of pain during intravenous propofol injection in 82 patients undergoing general anesthesia." | 9.07 | Tourniquet at 50 mm Hg followed by intravenous lidocaine diminishes hand pain associated with propofol injection. ( Holak, EJ; Mangar, D, 1992) |
| "A single-blind, randomised, controlled study was undertaken to compare the efficacy of three methods of preventing pain during injection of propofol on induction of anaesthesia." | 9.07 | Effect of prior administration of cold saline on pain during propofol injection. A comparison with cold propofol and propofol with lignocaine. ( Barker, P; Langton, JA; Murphy, P; Rowbotham, DJ, 1991) |
| "Pain on injection of propofol was assessed in a controlled, randomised study of 273 patients." | 9.07 | Modification of pain on injection of propofol--a comparison between lignocaine and procaine. ( A'Hern, RP; Edwards, J; Moriarty, J; Nicol, ME; Robbie, DS, 1991) |
| "A randomised, placebo controlled, double-masked study was undertaken in 115 patients undergoing cataract surgery to assess the efficacy of the anaesthetic cream EMLA (eutetic mixture of local anaesthetic, lignocaine-prilocaine) in alleviating the pain of retrobulbar injection." | 9.07 | A double-masked evaluation of lignocaine-prilocaine cream (EMLA) used to alleviate the pain of retrobulbar injection. ( Joyce, PW; Kirby, J; Sunderraj, P; Watson, A, 1991) |
| "The purpose of this study was to define the optimum dose of lignocaine required to reduce pain on injection of propofol." | 9.07 | Optimal dose of lignocaine for preventing pain on injection of propofol. ( Gehan, G; Karoubi, P; Leroy, A; Pourriat, JL; Quinet, F; Rathat, C, 1991) |
| "Previous reports have suggested that pain associated with the injection of lidocaine is related to the acidic pH of the solution." | 9.07 | Reduction in injection pain using buffered lidocaine as a local anesthetic before cardiac catheterization. ( Dehmer, GJ; Petrozzi, R; Sapin, P, 1991) |
| "A quantitative comparison was made of the effect of infiltration of local analgesics and topical analgesic cream (EMLA) on laser-induced pain and histamine-induced wheal, flare and itch." | 9.06 | A quantitative comparison of the effect of local analgesics on argon laser induced cutaneous pain and on histamine induced wheal, flare and itch. ( Arendt-Nielsen, L; Bjerring, P, 1990) |
| "The incidence of tourniquet pain was evaluated in two groups of patients with 20 each undergoing orthopedic surgery of the lower extremities during epidural anesthesia using plain solution of either 2% lidocaine or 0." | 9.06 | [The effect of epidural anesthesia on tourniquet pain: a comparison of 2% lidocaine and 0.5% bupivacaine]. ( Lai, KB; Lee, Y; Pan, PM; Tung, MC; Wei, TT; Who, LH; Wong, KL; Wu, KH, 1990) |
| "A prospective study with 161 patients was performed to investigate the effects of intravenous local anaesthetics on the pain of injection following etomidate injection." | 9.06 | [The modification of injection pain and the incidence of thrombophlebitis following etomidate]. ( Maier, C; Rühmann, I, 1990) |
| "A controlled randomised double-blind design was used to study the effect of lignocaine on the pain produced by intravenous injection of propofol." | 9.06 | Pain on injection of propofol. Methods of alleviation. ( Chadwick, S; Harper, NJ; Johnson, RA; Vohra, A, 1990) |
| "One hundred and twenty unpremedicated patients undergoing gynaecological surgery were randomly allocated to one of three equal treatment groups to assess the effectiveness of ethyl chloride in producing instant skin anaesthesia to prevent the pain of venepuncture from a 20 G cannula." | 9.06 | Ethyl chloride and venepuncture pain: a comparison with intradermal lidocaine. ( Armstrong, P; McKeown, D; Young, C, 1990) |
| "The aim of the study was to evaluate the effect of a lidocaine-prilocaine cream (EMLA cream, Astra) in relieving pain during arterial cannulation." | 9.06 | EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream. ( Danielson, K; Engberg, G; Henneberg, S; Nilsson, A, 1990) |
| "The prophylactic use of lidocaine in the patient with cardiac chest pain has been reported to reduce the incidence of sudden death from ventricular dysrhythmias in the hospital setting, but few studies have been done in the early prehospital phase." | 9.06 | Prophylactic lidocaine in the prehospital patient with chest pain of suspected cardiac origin. ( Aprahamian, C; Darin, J; Hargarten, KM; Mateer, JR; Stueven, HA; Thompson, BM, 1986) |
| "Both regional intravenous guanethidine and reserpine have been reported as effective in the treatment of reflex sympathetic dystrophy." | 9.06 | A comparison of regional intravenous guanethidine and reserpine in reflex sympathetic dystrophy. A controlled, randomized, double-blind crossover study. ( Gallo, JP; Kaul, AF; Lief, PA; Reisman, RM; Rocco, AG, 1989) |
| "The efficacy of lignocaine (1%) mixed with propofol in reducing pain on injection with propofol was studied in 40 children undergoing elective surgery in a double-blind, randomized comparison with glucose (5%)." | 9.06 | Propofol as an induction agent in children: pain on injection and pharmacokinetics. ( Iisalo, E; Kanto, J; Rosenberg, P; Valtonen, M, 1989) |
| "Eight modes of administration of propofol were assessed in order to minimise the pain of injection." | 9.06 | Propofol: clinical strategies for preventing the pain of injection. ( Norman, J; Saunders, DA; Scott, RP, 1988) |
| "The local analgesic efficacy of a cream formulation of lidocaine and prilocaine (EMLA) in reducing pain at venous cannulation was investigated in children scheduled for elective surgery." | 9.06 | Reduction of pain at venous cannulation in children with a eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication. ( Iisalo, E; Kanto, J; Lindberg, R; Manner, T; Scheinin, M; Viinamäki, O, 1987) |
| "The effect of the topical application of a lignocaine-prilocaine cream (EMLA) on the pain of venous cannulation was tested in a double-blind manner." | 9.06 | Double-blind evaluation of a lignocaine-prilocaine cream (EMLA) in children. Effect on the pain associated with venous cannulation. ( Korpela, R; Maunuksela, EL, 1986) |
| "Twenty-four patients with localized myofascial pain were treated with injections, 11 with 2 ml lidocaine 1% and 13 with 2 ml diclofenac (Voltaren) (50 mg) given in the trigger-point." | 9.06 | Diclofenac versus lidocaine as injection therapy in myofascial pain. ( Frost, A, 1986) |
| "In a randomized double-blind, cross-over study the effect of intravenous lidocaine (5 mg/kg body weight) on the symptoms and signs of painful diabetic neuropathy of more than 6 months duration has been evaluated." | 9.06 | Intravenous lidocaine infusion--a new treatment of chronic painful diabetic neuropathy? ( Angelo, HR; Dejgård, A; Hilsted, J; Kastrup, J; Petersen, P, 1987) |
| "A shortcut review was carried out to establish whether topical lidocaine was effective at reducing pain and improving oral intake in children with painful oral lesions." | 9.05 | BET 2: Does topical lidocaine improve oral intake in children with painful mouth ulcers? ( Daniel, RMD; Jason, SDO; Jeffrey, SJ, 2020) |
| " When compared to lidocaine, the preventive effect was not so excellent as the latter but injection pain induced by prophylactic occurred less." | 9.05 | The efficacy of Antipyretic Analgesics administration intravenously for Preventing Rocuronium-Associated Pain/Withdrawal Response: a systematic review and meta-analysis. ( Chen, J; Cui, Y; Liu, B; Wang, J, 2020) |
| "The aim of this study was to systematically review the effects of lidocaine mixed with epinephrine and bicarbonate in plastic surgery in terms of onset, duration, and the pain score." | 9.05 | Onset, Duration, and Pain Score Obtained Using Lidocaine Mixed With Epinephrine and Bicarbonate in Plastic Surgery. ( Hwang, K; Kim, H, 2020) |
| " A randomised double-blind study was performed to determine the efficacy of lidocaine in reducing pain and discomfort associated with venography." | 9.05 | Lidocaine and the reduction of post-venographic pain. ( Gent, M; Hirsh, J; Hull, RD; McLaughlin, D; Ockelford, PA; Powers, PJ; Strasberg, Z, 1984) |
| "In a study including a total of 175 children, ranging in age from 3 months to 3 years and suffering from otitis media, the analgesic effect of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol) syrup was compared with that of lidocaine 0." | 9.05 | Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. ( Michos, N; Stocker, H; Weippl, G, 1985) |
| "A 5% lidocaine-prilocaine local anaesthetic cream, EMLA (Eutectic Mixture of Local Anaesthetics), has proved to be an effective remedy for alleviation of venipuncture pain when applied to intact skin for 60 min." | 9.05 | [Pain relief in vein puncture. Application time and effectiveness of lidocaine-prilocaine-cream]. ( Dohlwitz, A; Uppfeldt, A, 1985) |
| "We studied 41 consecutive patients receiving intravenous (IV) diazepam in the preoperative holding area to evaluate whether low-dose IV lidocaine could ameliorate pain of the diazepam injection." | 9.05 | Lidocaine reduces intravenous diazepam pain. ( Ampel, L; Herr, RD; Natonson, R, 1985) |
| "Intra-arterial lidocaine has been utilized to decrease pain by administration prior to contrast material injections during aortofemoral arteriography in over 600 patients." | 9.04 | The use of intra-arterial lidocaine to control pain due to aortofemoral arteriography. ( Robbins, AH; Singer, RJ; Widrich, WC, 1977) |
| "Systematic review and meta-analysis to assess the effects of uterine or paracervical lidocaine application on pain control during IUD insertion." | 8.98 | Uterine or paracervical lidocaine application for pain control during intrauterine contraceptive device insertion: a meta-analysis of randomised controlled trials. ( Hernandez, AV; Martinez-Dominguez, SJ; Perez-Lopez, FR; Perez-Roncero, GR, 2018) |
| "To evaluate the effect and safety of 5-hydroxytryptamine (5-HT) receptor antagonist in alleviating the pain of patients under general anesthesia induced by rocuronium injection and preemptive analgesia." | 8.98 | The Effect of 5-Hydroxytryptamine Receptor Antagonist in Preventing Pain/Limb Shrinkage Reaction Associated with Rocuronium Injection. ( He, Q; Zhou, C; Zhu, Y, 2018) |
| "Pain on injection of lidocaine is often considered a necessary evil, but it can be reduced by simple means." | 8.95 | Reduced pain when injecting lidocaine. ( Finsen, V, 2017) |
| " All randomized controlled trials that using lidocaine for propofol injection pain in children were enrolled." | 8.95 | Efficacy of lidocaine on preventing incidence and severity of pain associated with propofol using in pediatric patients: A PRISMA-compliant meta-analysis of randomized controlled trials. ( Fu, YZ; Lang, BC; Yang, CS; Zhang, LL; Zhang, WS, 2017) |
| "The objectives of this review were to assess the ability of both pharmacological and non-pharmacological interventions to reduce or eliminate the pain that accompanies rocuronium bromide administration." | 8.93 | Pharmacological and non-pharmacological interventions for reducing rocuronium bromide induced pain on injection in children and adults. ( Ali, Z; Kalaivani, M; Prabhakar, H; Singh, GP; Smith, MA, 2016) |
| "The objective of this review was to determine the efficacy and adverse effects of lidocaine in preventing high-intensity pain on propofol injection." | 8.93 | Lidocaine for reducing propofol-induced pain on induction of anaesthesia in adults. ( Dej-Arkom, S; Euasobhon, P; Lumbiganon, P; Muangman, S; Pattanittum, P; Siriussawakul, A; Sriraj, W, 2016) |
| "68) indicating lidocaine was more effective than BaNS in providing pain relief (P < ." | 8.90 | Intradermal lidocaine or bacteriostatic normal saline to decrease pain before intravenous catheter insertion: a meta-analysis. ( Cook, P; Fink, R; Hoffecker, L; Kleiner, C; Makic, MB; Mancuso, M; Oman, KS; Schmiege, S; Wenger, B, 2014) |
| " The one small randomised double-blind placebo-controlled cross-over trial found in 2012, which included only 45 participants and compared intravenous lidocaine against placebo as a means of pain relief in people with burns still remains central to this review." | 8.90 | Intravenous lidocaine for the treatment of background or procedural burn pain. ( Cleland, H; Danilla, S; Mahar, PD; McGuinness, SK; Spinks, A; Tan, HB; Wasiak, J, 2014) |
| "This update identified one new randomised, double-blind, placebo-controlled, cross-over trial which included 45 participants and compared intravenous lidocaine against placebo as a means of pain relief in those with burns." | 8.88 | Intravenous lidocaine for the treatment of background or procedural burn pain. ( Cleland, H; Danilla, S; Mahar, P; McGuinness, SK; Spinks, A; Wasiak, J, 2012) |
| "Lidocaine administration produces pain due to its acidic pH." | 8.86 | Adjusting the pH of lidocaine for reducing pain on injection. ( Arora Gandhi, P; Cepeda, MS; Hudcova, J; Schumann, R; Thackrey, M; Tzortzopoulou, A, 2010) |
| "We reviewed previous reports cited in PubMed, Biosis and the Cochrane Library, identified by a professional librarian searching for English language-only randomized controlled studies involving the keywords, lidocaine, cystoscopy, gel and pain, yielding 14 studies." | 8.85 | Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief? ( Aaronson, DS; Davies, BJ; Hsieh, MH; Konety, BR; Smith, JF; Walsh, TJ, 2009) |
| "All RCTs and quasi-RCTs reporting use of cyclobenzaprine for treating MP with pain assessment as a primary or secondary outcome." | 8.85 | Cyclobenzaprine for the treatment of myofascial pain in adults. ( Andriolo, RB; Atallah, AN; da Silva, EM; El Dib, R; Grossmann, E; Januzzi, E; Leite, FM, 2009) |
| "Lidocaine is a use-dependent sodium channel blocker that produces analgesia when administered intravenously to patients with neuropathic pain." | 8.84 | Intravenous lidocaine for neuropathic pain: diagnostic utility and therapeutic efficacy. ( Carroll, I, 2007) |
| "A reasonable body of evidence, along with extensive clinical experience, suggests that intravenous lidocaine can have a useful pain-relieving effect and is worth consideration in palliative care patients." | 8.84 | Intravenous lidocaine: an outdated or underutilized treatment for pain? ( McCleane, G, 2007) |
| "To assess the safety and effectiveness of intravenous lidocaine as a means of pain relief versus no therapy, placebo, other drugs or two or more of the above therapies in combination in patients exposed to burn injury." | 8.84 | Lidocaine for pain relief in burn injured patients. ( Cleland, H; Wasiak, J, 2007) |
| "To determine the relative efficacy of lidocaine-prilocaine and tetracaine for procedural pain in children." | 8.81 | Lidocaine-prilocaine cream versus tetracaine gel for procedural pain in children. ( Gurguis, MG; Koren, G; Taddio, A, 2002) |
| "Pain on injection of propofol is a common problem, the cause of which remains unknown." | 8.80 | Pain on injection of propofol. ( Onsiong, MK; Tan, CH, 1998) |
| "The best intervention to prevent pain on injection with propofol is unknown." | 8.80 | Prevention of pain on injection with propofol: a quantitative systematic review. ( Picard, P; Tramèr, MR, 2000) |
| "Lidocaine aerosol sprayed on oral and/or nasal mucosa is beneficial for immediate pain relief in patients with acute trigeminal neuralgia exacerbations." | 8.31 | Lidocaine aerosol sprayed on oral and/or nasal mucosa for the rescue of acute trigeminal neuralgia exacerbations: A retrospective study. ( Luo, F; Shen, Y; Zhao, C; Zhou, X, 2023) |
| "When comparing with topical lidocaine/prilocaine (EMLA) cream, a 1:1 mixture of 1% lidocaine and epinephrine significantly alleviated pain during and after the corticosteroid injection." | 8.31 | Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study. ( Park, TH, 2023) |
| "To compare the onset, anesthesia depth, and duration of topical 10% lidocaine and EMLA cream." | 8.12 | Comparison of the onset, depth, and duration of cutaneous anesthesia between topical 10% lidocaine and EMLA creams: a randomized, intraindividual, comparative trial. ( Deewongkij, P; Junputipong, N; Kamanamool, N; Rojhirunsakool, S; Udompataikul, M, 2022) |
| "Lidocaine hydrochloride is frequently used for management of painful wounds." | 8.12 | 5% Lidocaine Hydrochloride Cream for Wound Pain Relief: A Multicentre Observational Study. ( Arnez, ZM; Davini, G; Dini, V; Janowska, A; Oranges, T; Papa, G; Romanelli, M; Stocco, C, 2022) |
| "In patients pretreated with lidocaine, no pain 56 (87." | 8.02 | Lidocaine for Reduction of Pain Induced by Propofol in a Tertiary Care Hospital: A Descriptive Cross-sectional Study. ( Bahadur Chand, M; Ghimire, B, 2021) |
| "To determine the effect of escalating doses of lidocaine infusion with or without added magnesium on pain levels and the duration of pain relief in patients with fibromyalgia (FM)." | 7.96 | Repeated Intravenous Lidocaine Infusions for Patients with Fibromyalgia: Higher Doses of Lidocaine Have a Stronger and Longer-Lasting Effect on Pain Reduction. ( Perelman, VS; Pugacheva, O; Voznyak, Y; Wansbrough, MCT; Wilderman, I; Zolnierczyk, L, 2020) |
| "To evaluate whether administration of lidocaine into the uterine artery for anesthesia immediately after uterine artery embolization (UAE) with trisacryl gelatin microspheres (TAGM) for leiomyoma is safe and effective." | 7.96 | Intra-Arterial Lidocaine Administration for Anesthesia after Uterine Artery Embolization with Trisacryl Gelatin Microspheres for Leiomyoma. ( Asato, A; Katsumori, T; Kotera, Y; Miura, H; Seri, S; Yoshikawa, T, 2020) |
| "To determine the efficacy of lidocaine versus bupivacaine when performing intranasal sphenopalatine ganglion (SPG) block for the treatment of headaches." | 7.96 | Lidocaine Versus Bupivacaine in the Treatment of Headache with Intranasal Sphenopalatine Nerve Block. ( Alli, A; Clark, L; Collins, Z; Fahrbach, T; Kirkpatrick, DL; Lemons, S; Madarang, EJ; Reeves, A; Townsend, T; Walter, C, 2020) |
| "Lidocaine infusion is often used as part of a perioperative, multimodal pain management plan." | 7.96 | Continuous Intravenous Lidocaine Provides Effective Pain Control in a Palliative Child: A Case Report. ( Bell, M; Kim, E; Le, S; Lo, C, 2020) |
| "The purpose of this study was to describe the therapeutic effectiveness/pain relief of moderate-dose lidocaine infusions in patients with chronic neuropathic pain." | 7.91 | Intravenous Lidocaine for Relief of Chronic Neuropathic Pain. ( Albala, MZ; Hudson, A; Lancaster, RJ; Leavitt, K; Margelosky, K; Walesh, M; Wren, K, 2019) |
| "Herein, it was investigated whether a complex of lidocaine with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) would present a better antinociceptive profile in vivo when compared with plain lidocaine in models of orofacial pain." | 7.91 | Comparison of antinociceptive effects of plain lidocaine versus lidocaine complexed with hydroxypropyl-β-cyclodextrin in animal models of acute and persistent orofacial pain. ( Araya, EI; Chichorro, JG; Claudino, RF; de Oliveira, SB; Ferreira, LEN; Franz-Montan, M; Gambeta, E, 2019) |
| "A short review was carried out to see if mixing lidocaine with propofol is a safe and effective method in reducing the commonly reported pain at the injection site." | 7.85 | BET 1: Lidocaine with propofol to reduce pain on injection. ( Baombe, JP; Howard, L, 2017) |
| "The aim of this study was to compare the pain-relieving effect of intracervical lidocaine gel with that of lidocaine spray or no local anaesthesia in decreasing pain during insertion of the intrauterine contraceptive device (IUCD)." | 7.85 | Lidocaine gel vs lidocaine spray in reducing pain during insertion of the intrauterine contraceptive device. ( Ahmed, A; Dief, O; El-Desouky, ES; Moussa, A; Torky, H, 2017) |
| "To evaluate topical treatment with clobetasol propionate and lidocaine in women with urethral pain syndrome (UPS) in a retrospective pilot study." | 7.83 | Urethral instillations of clobetasol propionate and lidocaine: a promising treatment of urethral pain syndrome. ( Hellberg, D; Lindström, AK; Lindström, BE, 2016) |
| " In this study, we investigated spontaneous pain and mechanical allodynia in a preclinical model of oral ulcerative mucositis after systemic administration of the chemotherapy drug 5-fluorouracil, using our proprietary pain assay system for conscious rats." | 7.83 | Distinct TRPV1- and TRPA1-based mechanisms underlying enhancement of oral ulcerative mucositis-induced pain by 5-fluorouracil. ( Goto, T; Harano, N; Hitomi, S; Inenaga, K; Inoue, H; Ito, M; Matoba, M; Miyano, K; Nodai, T; Ono, K; Uezono, Y; Watanabe, S; Yamaguchi, K, 2016) |
| "The aim of this study was to determine whether systemic administration of QX-314 reduces bone cancer pain through selective inhibition of transient receptor potential vanilloid subfamily 1 (TRPV1)-expressing afferents." | 7.83 | Systemic QX-314 Reduces Bone Cancer Pain through Selective Inhibition of Transient Receptor Potential Vanilloid Subfamily 1-expressing Primary Afferents in Mice. ( Fuseya, S; Kawamata, M; Kawamata, T; Minemura, H; Yamamoto, K; Yamaori, S, 2016) |
| "This study was designed to evaluate the efficacy and safety of CT-guided embolization of internal iliac artery aneurysm (IIAA) after repair of abdominal aortic aneurysm by transretroperitoneal approach using the lidocaine injection technique to iliacus muscle, making window for safe needle path for three patients for whom CT-guided embolization of IIAA was performed by transretroperitoneal approach with intramuscular lidocaine injection technique." | 7.81 | Transretroperitoneal CT-guided embolization of growing internal iliac artery aneurysm after repair of abdominal aortic aneurysm: a transretroperitoneal approach with intramuscular lidocaine injection technique. ( Choi, SJ; Chung, SY; Kim, HO; Kim, JK; Kim, SJ; Kim, YT; Lee, HK; Lim, NY; Park, JY, 2015) |
| "We investigated the analgesic effects of lidocaine (LDC) and lidocane derivative, QX-572, co-application on the evoked pain behaviour (complete Freund's Adjuvant (CFA)-induced) and spontaneous pain behaviour (formalin-induced) in mice." | 7.81 | Co-application of lidocaine and QX-572 induces divergent pain behaviours in mice. ( Gao, Y; Jin, D; Shao, CJ; Wang, D; Wang, DQ; Zhao, L, 2015) |
| "To compare the use of lubricant gel with lidocaine versus lubricant gel without anesthetic in flexible cystoscopy in terms of pain and tolerability." | 7.81 | Use of Lidocaine 2% Gel Does Not Reduce Pain during Flexible Cystoscopy and Is Not Cost-Effective. ( Arrabal-Martin, M; Arrabal-Polo, MA; Cano-Garcia, Mdel C; Casares-Perez, R; Merino-Salas, S, 2015) |
| "To compare retrospective use of oral sucrose (SUC) vs oral sucrose plus lidocaine ring block (SUC + RB) in the management of pain during neonatal circumcision." | 7.80 | Pre-emptive penile ring block with sucrose analgesia reduces pain response to neonatal circumcision. ( Fogel, J; Hsu, CD; Roman-Rodriguez, CF; Sherlock, DJ; Toussaint, T, 2014) |
| "5% lidocaine medicated plasters are a topical option in the treatment of peripheral neuropathic pain, as monotherapy or as an adjunct to systemic medication." | 7.80 | Use of 5% lidocaine medicated plasters for the treatment of pain in routine hospital practice: patient reported pain, functioning and satisfaction. ( Kadambande, S; Khot, S; Morgan, CL; Poole, CD, 2014) |
| "This study shows that lidocaine, a peripheral analgesic, significantly altered DMN connectivity and affected its relationship with pain-related networks." | 7.79 | Functional connectivity of the default mode network and its association with pain networks in irritable bowel patients assessed via lidocaine treatment. ( Craggs, JG; Letzen, JE; Perlstein, WM; Price, DD; Robinson, ME, 2013) |
| " Prior to the procedure, subjects rated anxiety on a numerical rating scale (NRS) from 0 (no anxiety) to 3 (extreme anxiety), and received standardized subcutaneous injections of lidocaine (using 25-G needle to infiltrate 2 cc 1% lidocaine) as local anesthesia." | 7.77 | Judging pain sensitivity with subcutaneous lidocaine injections. ( Hunt, P; Manabat, ER; Pujol, LA; Wang, D, 2011) |
| "Pretreatment with 60% lidocaine tape significantly reduces the pain associated with intralesional injection of TA." | 7.75 | Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid. ( Hyakusoku, H; Murakami, M; Tosa, M, 2009) |
| "The use of lidocaine gel intrarectal 2% before a prostate biopsy guided by ultrasound did not diminish the sensation of pain from the procedure in our patients, which was increased by the use of sterilized needles." | 7.75 | [Pain during transrectal ultrasound guided needle biopsy of the prostate: comparison of the use or not of lidocaine gel]. ( Destefano Urrutia, V; Díaz Pérez, GA; Meza Montoya, L; Morante Deza, C; Pow-Sang Godoy, M, 2009) |
| "The aim of this study was to establish the effect of lidocaine, a local anesthetic, on pain and itch using formalin-induced nociception and kappa opioid antagonist-induced scratching models in mice." | 7.75 | Inhibitory effect of lidocaine on pain and itch using formalin-induced nociception and 5'-guanidinonaltrindole-induced scratching models in mice: behavioral and neuroanatomical evidence. ( Cowan, A; Dun, NJ; Inan, S, 2009) |
| "The present study investigated the effects of different doses of intrathecal lidocaine on established thermal hyperalgesia and tactile allodynia in the chronic constriction injury model of neuropathic pain, defined the effective drug dose range, the duration of pain-relief effects, and the influence of this treatment on the body and tissues." | 7.75 | Effects of intrathecal lidocaine on hyperalgesia and allodynia following chronic constriction injury in rats. ( Gu, Y; Su, D; Tian, J; Wang, X; Wu, Y, 2009) |
| "The objective of the present study was to investigate the pain on injection of articaine with adrenaline, prilocaine with phenylpressin , and lidocaine with adrenaline." | 7.74 | A comparison of injection pain with articaine with adrenaline, prilocaine with phenylpressin and lidocaine with adrenaline. ( Celebi, N; Misir, F; Muğlali, M; Sumer, M, 2008) |
| "The proportion of chronic pain patients with suspected neuropathic pain who will have clinically meaningful pain relief with intravenous (IV) lidocaine and the clinical characteristics that identify these patients have not been described previously." | 7.74 | Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesia. ( Carroll, I; Gaeta, R; Mackey, S, 2007) |
| "To compare pain responses in stallions undergoing standing laparoscopic cryptorchidectomy following intratesticular or mesorchial infiltration of lidocaine." | 7.73 | Comparison of intraoperative pain responses following intratesticular or mesorchial injection of lidocaine in standing horses undergoing laparoscopic cryptorchidectomy. ( Hendrickson, DA; Joyce, J, 2006) |
| "Systemic lidocaine can relieve various forms of neuropathic pain that develop after nerve injury." | 7.72 | Multiple phases of relief from experimental mechanical allodynia by systemic lidocaine: responses to early and late infusions. ( Araujo, MC; Sinnott, CJ; Strichartz, GR, 2003) |
| "Amiodarone was found to produce a statistically significant decrease in heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain after intraperitoneal injection." | 7.72 | Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain. ( Datta, S; Glusman, S; Torres, M; Waghray, T, 2004) |
| "We present a case of persistent central pain after encephalitis in a patient who had long-term pain relief after a series of IV lidocaine infusions." | 7.72 | The long-term effect of repeated intravenous lidocaine on central pain and possible correlation in positron emission tomography measurements. ( Annoni, JM; Cahana, A; Carota, A; Montadon, ML, 2004) |
| " Three studies are presented that provide preliminary evidence for the utility of the NPS for characterizing distinct pain qualities and changes in pain qualities in patients treated with the lidocaine patch 5% for a variety of neuropathic and non-neuropathic chronic pain conditions, including low-back pain, osteoarthritis, post-herpetic neuralgia, and painful diabetic neuropathy." | 7.72 | Introduction: chronic pain studies of the lidocaine patch 5% using the Neuropathic Pain Scale. ( Jensen, MP, 2004) |
| "Parenteral lidocaine has been reported to relieve neuropathic pain and/or pain refractory to opioid therapy." | 7.72 | Intravenous lidocaine relieves severe pain: results of an inpatient hospice chart review. ( Cox, MC; Kronenberg, R; Naco, GC; Thomas, J; von Gunten, CF; Wallace, M, 2004) |
| "This study examined the safety, tolerability, and efficacy of iontophoresis with 30 mA of lidocaine for dermal anesthesia in children younger than 84 months in the emergency department and the usefulness of a modified version of the Pre-verbal, Early Verbal Pediatric Pain Scale (M-PEPPS)." | 7.71 | Safety, tolerability, and efficacy of iontophoresis with lidocaine for dermal anesthesia in ED pediatric patients. ( Jordan, P; Schultz, AA; Strout, TD; Worthing, B, 2002) |
| "Lidocaine infiltration was performed if any sign of pain was observed." | 7.71 | [Suture of skin lacerations using LAT gel (lidocaine, adrenaline, tetracaine)]. ( Alió Y Sanz, JL; Chipont Benabent, E; García-Hermosa, P, 2001) |
| "Repeated application of capsaicin on the tongue has been used as a human oral pain model to assess topical anesthetic-analgesic drugs." | 7.71 | A human oral capsaicin pain model to assess topical anesthetic-analgesic drugs. ( Dallel, R; Dubray, C; Ngom, PI; Woda, A, 2001) |
| "Eighty-five patients (90%), responders to lidocaine, had a pain relief and 71 patients (85%), no responders to lidocaine, did not have improvement by taking oral drugs." | 7.70 | [The predictive lidocaine test in treatment of neuropathic pain]. ( Trentin, L; Visentin, M, 2000) |
| " Specifically, the actions of brainstem cholecystokinin and the possible importance of sustained afferent input from injured nerve fibers were determined using pharmacological and physiological approaches in rats with SNL." | 7.70 | Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat. ( Kovelowski, CJ; Lai, J; Malan, TP; Ossipov, MH; Porreca, F; Sun, H, 2000) |
| " Recently, observations have been made that associate the use of hyperbaric lidocaine with bilateral leg pain." | 7.69 | Bilateral leg pain following lidocaine spinal anaesthesia. ( Chadwick, HS; Lowmiller, M; Pinczower, GR; Woodland, R, 1995) |
| "We evaluate the analgesic efficacy and safety of 9% (wt/vol) lidocaine (base) in petrolatum/paraffin ointment in patients with acute herpes zoster." | 7.69 | Treatment of the cutaneous pain of acute herpes zoster with 9% lidocaine (base) in petrolatum/paraffin ointment. ( Cork, RC; Dunston, A; Eyrich, J; Heitler, D; Johnson, W; Lopez-Anaya, A; Naraghi, M; Ragan, A; Riopelle, AJ; Riopelle, J, 1994) |
| "Lidocaine administered intravenously is efficacious in treating neuropathic pain at doses that do not cause sedation or other side effects." | 7.69 | Derivation and cross-validation of pharmacokinetic parameters for computer-controlled infusion of lidocaine in pain therapy. ( Brose, W; Gaeta, R; Gregg, KM; Minto, CF; Schnider, TW; Shafer, SL, 1996) |
| "To assess the benefit of ketamine addition to a morphine-clonidine-lidocaine mixture administered continuously by the intrathecal route for the treatment of cancer pain." | 7.69 | [Cancer pain: beneficial effect of ketamine addition to spinal administration of morphine-clonidine-lidocaine mixture]. ( Lemos, D; Muller, A, 1996) |
| " We report two cases of bilateral pain in the lower extremities appearing 20-24 h after intradural anesthesia with 2% hyperbaric lidocaine." | 7.69 | [Pain in the lower extremities after subarachnoid block with lidocaine]. ( Gómez, E; Masip, R; Rull, M; Sala, P; Saludes, J, 1996) |
| "In this study, 8 patients with central pain syndromes, 6 with hemispheric lesions, and 2 with spinal cord lesions were treated with a 1 mg/kg dose of intravenous lidocaine." | 7.68 | Response of central pain syndromes to intravenous lidocaine. ( Backonja, M; Gombar, KA, 1992) |
| "We have developed transdermally applicable 10% lidocaine aqueous gel containing an absorption promoter and applied it for 15 patients suffering from severe pain in acute or subacute phase of herpes zoster." | 7.68 | [Transdermal application of 10% lidocaine-gel for management of pain associated with herpes zoster]. ( Ikuta, Y; Kano, T; Mishima, M; Morioka, T; Nakano, M; Shimoda, O; Takaki, M; Tashima, T; Tashiro, M, 1993) |
| "The author studied the use of intravenous Propofol for the relief of pain." | 7.68 | [Changes in the pain produced by the peripheral venous injection of propofol when it is combined with lidocaine or fentanyl]. ( Croston, J; de Henriquez, L; de Jiménez, L; Espinosa, V, 1992) |
| "The effect of pH neutralization on the pain experienced during intradermal lidocaine administration was investigated in a prospective blind study of 20 adult volunteers." | 7.68 | Neutralized lidocaine: use in pain reduction in local anesthesia. ( Bancroft, JW; Becker, GJ; Benenati, JF; Katzen, BT; Zemel, G, 1992) |
| "The analgesic effect of a lidocaine/prilocaine cream (EMLA) for the curettage of molluscum contagiosum was evaluated in 55 children aged 3-14 years." | 7.67 | Curettage of molluscum contagiosum in children: analgesia by topical application of a lidocaine/prilocaine cream (EMLA). ( Edmar, B; Gisslén, H; Lillieborg, S; Nordin, P; Rosdahl, I, 1988) |
| "Intravenous infusion of lidocaine has a pain-relieving effect in patients with painful diabetic neuropathy." | 7.67 | Lidocaine treatment of painful diabetic neuropathy and endogenous opioid peptides in plasma. ( Angelo, H; Bach, FW; Dejgård, A; Ekman, R; Jensen, S; Kastrup, J; Petersen, P, 1989) |
| "Assessment of pain on injection of the emulsified formulation of di-isopropylphenol (propofol, 'Diprivan') was undertaken in 120 unpremedicated patients and comparison made with thiopentone." | 7.67 | Assessment and modification of pain on induction with propofol (Diprivan). ( Lees, NW; McCulloch, MJ, 1985) |
| "In 50 patients subjected to aorto-femoral arteriography, the examination was carried out with and without the addition of 1 cm3 of 2% lidocaine per 10 cm3 of contrast medium; in 43/50 lidocaine led to a more or less notable reduction in pain without side-effects." | 7.66 | [The intra-arterial use of lidocaine to reduce pain in aorto-femoral arteriography (author's transl)]. ( Caresano, A; Del Favero, C; Lanocita, M; Magistretti, G; Martinenghi, CO; Neri, C, 1978) |
| "Surgical incisions were infiltrated subcutaneously with lidocaine without adrenaline or NaCl (placebo)." | 7.30 | Evaluation of primary wound healing and potential complications after perioperative infiltration with lidocaine without adrenaline in surgical incisions in dogs and cats. ( Bergström, AF; Engdahl, KS; Herlofson, EAG; Tavola, F, 2023) |
| "Pain was measured using the Visual Analogue Scale." | 7.30 | Pain Relief Durations of Different Concentrations of Lidocaine in Wide Awake Hand Surgery: A Prospective Randomised Clinical Trial. ( Ahmad, H; Bashir, MM; Jan, SN; Shami, HB; Tayab, Z, 2023) |
| "Lidocaine gel was an effective drug that can be used to attenuate the incidence rate of post-operative sore throat." | 7.30 | Comparing the effectiveness of topical dexamethasone emollient, lidocaine gel, and glycerin emollient on the endotracheal tube for postoperative hoarseness of voice, sore throat, and laryngospasm. ( Jabbar, ML; Mahboba, JH; Meazher, N, 2023) |
| "Cutaneous warts are treated by different treatments with various efficacy." | 7.11 | Comparison of the efficacy of intralesional 5-fluorouracil/lidocaine/epinephrine injection with cryotherapy to treat common and palmoplantar warts: A randomized, controlled trial. ( Bagheri, Z; Sarani, MB; Sepaskhah, M, 2022) |
| "Lidocaine spray treatment significantly lowered the pain scores compared with placebo (p < 0." | 6.82 | Effect of lidocaine spray in pain management during office-based endometrial sampling: A randomised placebo-controlled trial. ( Acmaz, G; Aksoy, H; Aksoy, U; Aydin, T; Babayigit, MA; Ozyurt, S; Yücel, B, 2016) |
| "Pain was evaluated with Visual Analog Scale, when the cervical canal was passed, while within the cavity and at 10 min after procedure." | 6.82 | The Effect of Intrauterine Lidocaine and Rectal Indomethacin on Pain during Office Vaginoscopic Hysteroscopy: Randomized Double-Blind Controlled Study. ( Babaoğlu, B; Guraslan, H; Polat, M; Senturk, MB; Yaşar, L, 2016) |
| "Primary mechanical hyperalgesia at the shoulders and buttocks decreased significantly more after lidocaine than saline injections (p = 0." | 6.79 | Analgesic and anti-hyperalgesic effects of muscle injections with lidocaine or saline in patients with fibromyalgia syndrome. ( Bartley, E; Price, DD; Robinson, ME; Staud, R; Weyl, EE, 2014) |
| "Pain was evaluated using a visual analog scale." | 6.78 | The evaluation of hyaluronic acid, with and without lidocaine, in the filling of nasolabial folds as measured by ultrastructural changes and pain management. ( Cornejo, P; Cruz, I; Isarría, MJ; Moreno-Moraga, J; Muñoz, E; Pérez, G; Royo de la Torre, J, 2013) |
| "Propofol is a widely used anesthetic drug because of its minor complication and also its fast effect." | 6.77 | Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial. ( Ayatollahi, V; Behdad, S; Kargar, S; Yavari, T, 2012) |
| "Opioid-refractory pain is distressing because it is notoriously difficult to treat." | 6.74 | A phase II pilot study to evaluate use of intravenous lidocaine for opioid-refractory pain in cancer patients. ( Haji, AG; Jain, D; Palat, G; Rajagopal, MR; Sharma, S; Singh, C, 2009) |
| "Fibromyalgia Impact Questionnaire (FIQ), Health Assessment Questionnaire, and a visual analog scale (VAS) for pain were applied before the first lidocaine infusion, immediately after the fifth infusion and 30 days after the fifth infusion." | 6.74 | Intravenous lidocaine for fibromyalgia syndrome: an open trial. ( Harth, F; Kaiber, F; Machado, F; Malucelli, T; Schafranski, MD; Schmidt, C; Takeshi, H, 2009) |
| "The lidocaine patch 5% was generally well tolerated and no patients discontinued due to treatment-related adverse events." | 6.71 | Topical lidocaine patch 5% may target a novel underlying pain mechanism in osteoarthritis. ( Burch, F; Codding, C; Galer, BS; Gammaitoni, AR; Patel, N; Sheldon, E, 2004) |
| " In groups 6 and 7, additional fentanyl doses were lower than in the other groups, but only in group 7 was the total fentanyl dosage low." | 6.71 | Effectiveness of eutectic mixture of local anesthetic cream and occlusive dressing with low dosage of fentanyl for pain control during shockwave lithotripsy. ( Basar, H; Basar, MM; Batislam, E; Ozcan, S; Tuglu, D; Yilmaz, E, 2005) |
| "The pain was rated by each patient on a 100-mm visual analogue scale (VAS)." | 6.69 | Lidocaine-prilocaine cream (EMLA Cream) as a topical anaesthetic for the cleansing of leg ulcers. The effect of length of application time. ( Holst, RG; Kristofferson, A, 1998) |
| "Pain was not different in the two groups after tourniquet release." | 6.69 | Adding clonidine to lidocaine for intravenous regional anesthesia prevents tourniquet pain. ( Bernard, JM; Bonnet, F; Gentili, M, 1999) |
| " The authors conclude that EMLA is safe but not efficacious for relieving pain from heel lance in preterm infants." | 6.69 | Management of pain from heel lance with lidocaine-prilocaine (EMLA) cream: is it safe and efficacious in preterm infants? ( Aranda, J; Jack, A; Johnston, C; Koren, G; Narciso, J; Stevens, B; Stremler, R; Taddio, A, 1999) |
| "Pain was assessed by determination of heart rate, respiratory rate, and behavioral distress scoring." | 6.69 | A randomized, controlled trial of a eutectic mixture of local anesthetic cream (lidocaine and prilocaine) versus penile nerve block for pain relief during circumcision. ( deBlieck, E; Fortune, K; Generelli, P; Howard, CR; Howard, FM; tenHoopen, C; Zolnoun, D, 1999) |
| "Pain was assessed according to a verbal rating scale and on a 100 mm visual analogue scale." | 6.67 | Pain control in the surgical debridement of leg ulcers by the use of a topical lidocaine--prilocaine cream, EMLA. ( Andrén, B; Grafford, K; Holm, J, 1990) |
| "In 10 cancer patients with cutaneous allodynia, intravenous lidocaine (5 mg/kg body weight) or 0." | 6.66 | Trial of intravenous lidocaine on painful neuropathy in cancer patients. ( Banning, AM; Ellemann, K; Geertsen, P; Jensen, TS; Sjögren, P; Smith, T, 1989) |
| "Three of 4 patients with accompanying phantom limb pain noted an increase in pain after the injection of gallamine." | 6.66 | Pain responses to perineuromal injection of normal saline, gallamine, and lidocaine in humans. ( Burchiel, KJ; Chabal, C; Jacobson, L; Russell, LC, 1989) |
| "Dercum's disease (adiposis dolorosa) is associated with very painful subcutaneous fatty deposits normally localized to the lower extremities in which pain treatment is usually unsuccessful." | 6.66 | Dercum's disease (adiposis dolorosa). Treatment of the severe pain with intravenous lidocaine. ( Kastrup, J; Petersen, P, 1987) |
| "Pain was evaluated using a three-graded verbal rating scale." | 6.66 | A lignocaine-prilocaine cream reduces venipuncture pain. ( Möller, C, 1985) |
| "Pain was registered on a 10-cm visual analogue scale." | 6.66 | Clinical study of a lignocaine-prilocaine cream to relieve the pain of venepuncture. ( Carlsson, P; Hallén, B; Uppfeldt, A, 1985) |
| "To study the incidence of pain upon injection of 1% propofol (Propofol-Lipuro 1%, B." | 6.21 | [Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides]. ( Ayuso, MA; Fernández, J; Gomar, C; Luis, M; Sala, X, 2004) |
| "To determine whether application of topical aqueous lidocaine to a laceration attenuates the pain from the subsequent lidocaine injection in children." | 6.18 | Use of topical lidocaine in pediatric laceration repair: a review of topical anesthetics. ( Rosenberg, NM; Simpson, P; Stewart, GM, 1998) |
| "Children who received lidocaine-prilocaine emulsion reported less pain (mean FPS score = 1." | 6.17 | Age-related response to lidocaine-prilocaine (EMLA) emulsion and effect of music distraction on the pain of intravenous cannulation. ( Abu-Saad, HH; Arts, SE; Champion, GD; Crawford, MR; Fisher, RJ; Juniper, KH; Ziegler, JB, 1994) |
| "Intravesical instillation of TRG-100 was found to be safe and efficient in reducing pain and irritative bladder symptoms in our study population." | 5.91 | Open Label, Pilot Evaluation of the Safety and Efficacy of Intravesical Sustained Release System of Lidocaine and Oxybutynin (TRG-100) for Patients With Interstitial Cystitis/Bladder Pain Syndrome, Overactive Bladder and Patients With Retained Ureteral St ( Ala-Adin, N; Chertin, B; Dothan, D; Gordon, A; Hatumi, S; Kafka, I; Malchi, N; Moldwin, R; Nassar, T; Perez, D; Raisin, G; Shenfeld, O; Touitou, D, 2023) |
| "Headache after subarachnoid hemorrhage and corresponding craniotomy with aneurysm clipping can be severe and difficult to treat." | 5.72 | Lidocaine Infusion for the Treatment of Headache Associated With Subarachnoid Hemorrhage: A Case Report. ( Crowley, JW; Dickerson, JR; Douangpraseuth, S; Newton, FA; Salgado, F, 2022) |
| "Since one of the nurse's duties is to employ different methods to reduce pain caused by treatment procedures, this study was conducted to determine the effect of lidocaine spray and ice spray on pain intensity at the muscle injection site." | 5.69 | Comparative Study of the Effect of Lidocaine Spray and Ice Spray on the Pain Intensity During Intramuscular Injection: A Randomized Clinical Trial. ( Bordbar, R; Hasheminik, M; Jamalinik, M; Khaleghipour, M; Khorashadizadeh, F; Lakziyan, R; Paivar, B; Shafigh, N; Siavoshi, M, 2023) |
| "To compare effectiveness of ice pack to topical lidocaine-prilocaine for pain reduction during axillary laser hair removal." | 5.69 | Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial. ( Alam, M; Anvery, N; Brieva, JC; Christensen, RE; Dirr, MA; Geisler, A; Roongpisuthipong, W; Schaeffer, M; Waldman, A, 2023) |
| "The aim of this prospective, double-blind, randomized controlled trial was to compare the effect of oral premedication of meloxicam, ketorolac, dexamethasone, ibuprofen, or placebo on the success of inferior alveolar nerve blocks (IANB) of mandibular posterior teeth in patients experiencing symptomatic irreversible pulpitis." | 5.69 | Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial. ( Elnaghy, AM; Elsaka, SE; Elshazli, AH, 2023) |
| "IV Lidocaine did not meet the criteria for non-inferiority with lower prehospital pain reduction than fentanyl but was safe and better tolerated as analgesia in ST-elevation myocardial infarction (STEMI)." | 5.69 | LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial. ( Andrew, E; Bernard, S; Brennan, A; Dinh, D; Fernando, H; Lefkovits, J; Milne, C; Myles, PS; Nehme, Z; O'Brien, J; Peter, K; Smith, K; Stephenson, M; Stub, D; Taylor, AJ, 2023) |
| "Compound lidocaine/prilocaine cream combined with tetracaine may be a more effective approach for preventing coughing and stabilising circulation during extubation following general anaesthesia." | 5.69 | Compound lidocaine/prilocaine cream combined with tetracaine prevents cough caused by extubation after general anaesthesia: a randomised controlled trial. ( Gao, J; Li, T; Li, Y; Wang, M; Zhang, E; Zhang, H; Zhang, L; Zhao, X, 2023) |
| "This randomized double-blinded trial aimed to compare the anesthetic success of inferior alveolar nerve blocks (IANBs) with 2% lidocaine in mandibular molars with symptomatic irreversible pulpitis (SIP) after oral premedication of prednisolone, dexamethasone, and ketorolac with placebo." | 5.69 | Effect of Preoperative Oral Steroids in Comparison to Anti-inflammatory on Anesthetic Success of Inferior Alveolar Nerve Block in Mandibular Molars with Symptomatic Irreversible Pulpitis-A Double-blinded Randomized Clinical Trial. ( Hegde, V; Kulkarni, V; Nagendrababu, V; Setzer, FC; Shaikh, S; Shanmugasundaram, S; Suresh, N, 2023) |
| "This study aimed to compare the effects of cooling and lidocaine sprays on needle insertion pain in hemodialysis patients." | 5.69 | Cooling spray or lidocaine spray and needle insertion pain in hemodialysis patients: an open-label cross-over randomized clinical trial. ( Armat, MR; Eshghi, M; Hejazi, S; Hoseini Azizi, T; Kameli, A; Khosravi Pour, A, 2023) |
| " Pain scores were reduced at 1 hour for the lidocaine (OR 4." | 5.69 | Topical Lidocaine or Lidocaine/Diltiazem Ointment Following Rubber Band Ligation of Hemorrhoids: A Prospective 3-Armed Randomized Controlled Trial. ( Carroll, R; Draganic, B; Kwok, AMF; Leigh, L; Smith, SR; Zhao, J, 2023) |
| "This study compared the level of lubricity and pain reduction of a novel shea lubricant to 2% lidocaine gel during digital rectal examination (DRE)." | 5.69 | Comparing the effectiveness and lubricity of a novel Shea lubricant to 2% lidocaine gel for digital rectal examination: a randomized non-inferiority trial. ( Adanu, KK; Adedia, D; Ali, MA; Amegan-Aho, K; Iroko, D; Kpodonu, J; Ndudiri, OV; Oyortey, MA, 2023) |
| "No study has assessed the effects of the incorporation of isolated lidocaine into botulinum toxin for reducing its pain or complications." | 5.69 | Effects of lidocaine incorporation (without epinephrine) on pain and 2-week complications of botulinum toxin: a double-blind randomized placebo-controlled clinical trial. ( Bagheri, D; Fateh, A; Kahali, R; Rakhshan, V; Sarkarat, F, 2023) |
| "Analgesia, Fentanyl, Lidocaine spray, Pain, Rib fracture, Tramadol." | 5.69 | Comparison of the Analgesic Efficacy of Lidocaine Spray versus Tramadol and Fentanyl for Pain Control in Rib Fractures. ( Donmez, S; Erdem, AB; Sener, A, 2023) |
| "Regardless of the positive attributes of propofol, it is frequently associated with pain on injection." | 5.69 | Prevention of pain on injection of propofol using ice gel pack versus pre-treatment with lignocaine: a randomized controlled trial. ( Chauhan, R; Karki, Y; Luthra, A; Meena, SC; Sarna, R; Singh, N; Thappa, P, 2023) |
| "The local use of lidocaine spray in patients with TIVAP is effective, acceptable, and safe to alleviate the pain caused by non-coring needle puncture." | 5.69 | Effect of lidocaine spray on reliving non-coring needle puncture-related pain in patients with totally implantable venous access port: a randomized controlled trial. ( Chang, J; Niu, S; Ye, L; Zhang, H; Zhang, Y; Zhu, Y, 2023) |
| "The use of an endotracheal tube (ET) cuff filled with alkalized lidocaine (AL) can suppress ET-induced emergence phenomena, such as hypertension, tachycardia and coughing, and postoperative sore throat (POST) and hoarseness (PH)." | 5.69 | Alkalized lidocaine in a tapered cuff suppresses endotracheal tube-induced hemodynamic changes: a randomized controlled trial. ( Ishida, K; Ito, M; Kawamata, M; Maruyama, Y; Shen, D; Tanaka, S; Yoshiyama, Y, 2023) |
| "Intravertebral injections of lidocaine during PKP can successfully reduce intraoperative pain." | 5.69 | Intraoperative analgesic effect of intravertebral lidocaine injection during percutaneous kyphoplasty in the treatment of thoracolumbar compression fractures in elderly patients. ( Chang, X; Liu, J; Wang, J; Yan, H; Yin, J; Zhang, Y; Zhao, X, 2023) |
| "To investigate the possible advantage of topical lidocaine and intravenous midazolam in preventing spasm and pain related to the radial artery." | 5.69 | Topical Lidocaine And Or/ Intravenous Midazolam Before Radial Coronary Angiography To Prevent Radial Artery Spasm. ( Elattar, MM; Haseeb, WA; NBiomy, R; Salama, MK, 2023) |
| "The current study compares articaine 4% with lidocaine 2% in terms of injection pain and effectiveness of anesthesia when treating permanent mandibular first molars (PMFMs) affected by molar incisor hypomineralization (MIH)." | 5.69 | Comparative study of articaine 4% versus lidocaine 2% in the local anesthesia of permanent mandibular first molars affected by MIH: a randomized controlled trial. ( Haidar, M; Raslan, N, 2023) |
| " In this clinical trial, we conducted a comparative analysis of the pain-related behavioral, physiological, and hematological performance of calves that were administered with either lidocaine plus normal saline (n = 15) or lidocaine plus meloxicam (n = 15) before undergoing disbudding operations." | 5.69 | A Clinical Trial on the Welfare Effects of Administering Meloxicam to 10 to 21 Day Dairy Calves Following Caustic Paste Disbudding. ( Cui, H; Deng, J; Fang, J; Geng, Y; Guo, H; Hu, Y; Huang, F; Kumbhar, MA; Li, Z; Qi, J; Ren, Z; Shah, AM; Shen, L; Yu, S; Zuo, Z, 2023) |
| "The analgesic efficacy of lidocaine 10% spray, etofenamate spray, and placebo spray used together with standard dexketoprofen 50 mg intravenous treatment in the pain management of rib fractures were similar to each other and although there was a difference at the 120th min, this difference was not statistically significant." | 5.69 | Placebo-controlled randomized double-blind comparison of the analgesic efficacy of lidocaine spray and etofenamate spray in pain control of rib fractures. ( Altas, F; Dönmez, S; Erdem, AB; Mutlu, Rİ; Şener, A, 2023) |
| "In women who underwent breast surgery, IV lidocaine bolus administered just before extubation attenuated bucking, cough and sore throat, and PONV for 24 hours after general anesthesia, without prolonging the emergence." | 5.69 | Effects of an intravenous lidocaine bolus before tracheal extubation on recovery after breast surgery - Lidocaine at the End (LATE) study: a randomized controlled clinical trial. ( Mraovic, B; Šimurina, T, 2023) |
| "Methylene blue (MB) is a blue cationic thiazine dye and currently used in different medical settings." | 5.62 | Methylene blue induces an analgesic effect by significantly decreasing neural firing rates and improves pain behaviors in rats. ( Han, HC; Lee, SW; Moon, SW; Park, JS; Suh, HR, 2021) |
| " We affirm the fact that the combination of EMLA + Sucrose + RB is highly effective for managing pain during circumcision and further reduction of already low scores might not be possible." | 5.51 | Music as an adjunct to combination analgesia for neonatal circumcision: A randomized controlled trial. ( Abi-Gerges, C; Charafeddine, L; El-Hout, Y; Fayad, J; Hafez, B; Lakissian, Z; Sharara-Chami, R; Tamim, H; Tazian, V; Zaghal, A, 2022) |
| "We tested the following hypothesis: The addition of intranasal fentanyl to the standard practice of local infiltration with lidocaine would provide better pain control than lidocaine alone for adult ED patients undergoing I&D." | 5.51 | A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess. ( Baer, J; Feliciano, C; Friedman, BW; Gupta, C; Latev, A; Sharpe, S, 2022) |
| "The results of this study showed that target-controlled plasma infusion of lidocaine can reduce propofol consumption in patients undergoing vocal cord polypectomy by supporting laryngoscopy, and the hemodynamics are more stable and reduce the coughing reaction in the wake period and throat pain after extubation without adverse events." | 5.51 | The effects of target-controlled infusion of lidocaine undergoing vocal cord polypectomy: A randomized controlled trial (CONSORT compliant). ( Bi, X; Cai, C; Hang, Q; Qi, Y; Wu, R; Zhou, L, 2022) |
| "Successful anesthesia (defined as no or mild pain during any of steps and no need for additional injection) is obtained in 12% of patients in the lidocaine group, while DEX-lidocaine group increased the success rate of IANB to 72% (p-value = 0." | 5.51 | Efficacy of adding dexmedetomidine to lidocaine to enhance inferior alveolar nerve block in patients with asymptomatic irreversible pulpitis: double-blind randomized clinical trial. ( Moshari, A; Moshari, M; Vahedi, Z, 2022) |
| "This randomized study suggests that topical 1% lidocaine ear drops with paracetamol or ibuprofen seems to provide effective and rapid relief for children presenting with ear pain attributed to AOM." | 5.51 | The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media. ( Alabaz, D; Albayrak, E; Bedir, T; Bozdemir, ŞE; Büyükcam, A; Çelebi, S; Çiftçi, E; İlarslan, EÇ; Kara, A; Kara, M; Kara, SS; Kara, TT; Karakaşlılar, S; Karbuz, A; Kaya, C; Öz, FN; Özdemir, H; Sali, E; Somer, A; Sönmez, G; Sütçü, M; Tezer, H, 2022) |
| "199 adults aged ≥40 years with hip osteoarthritis and at least moderate pain: 67 were randomly assigned to receive advice and education (best current treatment (BCT)), 66 to BCT plus ultrasound guided injection of triamcinolone and lidocaine, and 66 to BCT plus ultrasound guided injection of lidocaine." | 5.51 | Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial. ( Bromley, K; Cherrington, A; Foster, NE; Hall, A; Hennings, S; Holden, MA; Hughes, E; Hughes, G; Jinks, C; Kigozi, J; Lewis, M; Mallen, CD; Menon, A; Oppong, R; Paskins, Z; Peat, G; Roberts, P; Roddy, E; Stevenson, K, 2022) |
| "The primary outcome was the efficacy of ondansetron compared to lidocaine and placebo for the reduction of propofol injection pain." | 5.51 | A comparison of ondansetron and lidocaine in reducing injection pain of propofol: a randomized controlled study. ( Chaofan, S; Kosem, R; Plansangkate, P; Tanasansuttiporn, J; Termthong, S; Wasinwong, W, 2022) |
| "In this study, we aimed to evaluate the effect of administering lidocaine as a local anesthetic at the puncture site prior cannulation on reduction of pain during intravenous cannulation (IVC)." | 5.51 | Padded Dressing with Lidocaine HCL for Reducing Pain during Intravenous Cannulation in Adult Patients: A Randomized Controlled Clinical Trial. ( Kartufan, FF, 2022) |
| "To compare pain scores with preprocedure oral phenazopyridine vs intravesical lidocaine in women undergoing intradetrusor onabotulinumtoxinA injections for idiopathic overactive bladder." | 5.51 | Oral phenazopyridine vs intravesical lidocaine for bladder onabotulinumtoxinA analgesia: a randomized controlled trial. ( Jacobs, KM; Raker, CA; Siddique, M; Stewart, LE; Sung, VW, 2022) |
| " We randomized participants presenting for office dilation and aspiration under minimal sedation stratified by procedural indication (induced abortion vs early pregnancy loss) to a 20-mL buffered 1% lidocaine paracervical block or a 40-mL buffered 0." | 5.51 | Effect of Paracervical Block Volume on Pain Control for Dilation and Aspiration: A Randomized Controlled Trial. ( Averbach, S; Crouthamel, B; Economou, N; Kully, G; Meckstroth, K; Mody, SK; Rible, R, 2022) |
| " Therefore, we designed a randomized, double-blind, placebo-controlled clinical trial with a 2-period crossover design to study (1) behavioral incentives to promote exercise and (2) corticosteroid injections to reduce pain and improve function in patients with KOA when compared to lidocaine only." | 5.51 | Protocol for a multi-center randomized controlled trial to evaluate the benefits of exercise incentives and corticosteroid injections in osteoarthritis of the knee (MOVE-OK). ( Baker, JF; Doherty, C; England, BR; Kerr, G; Leach, W; Neogi, T; Ogdie, A; Olave, M; Quinones, M; Scanzello, CR; White, D; Wysham, K, 2022) |
| "The aim of this study was to assess inferior alveolar nerve block (IANB) success of 2% mepivacaine (Scandonest 2%, Septodont, France) and 4% articaine (Septanest 4%, Septodont) in patients with symptomatic irreversible pulpitis (SIP) in mandibular molars during access cavity preparation and instrumentation." | 5.51 | Inferior alveolar nerve block success of 2% mepivacaine versus 4% articaine in patients with symptomatic irreversible pulpitis in mandibular molars: A randomized double-blind single-centre clinical trial. ( Amin, SAW; Bedier, MM; El Boghdadi, RM; Ezzat, K; Fouda, MY; Gawdat, SI; Habib, MFOM; Marzouk, A; Tarek, S; Teama, SME, 2022) |
| "Two randomized, double-blinded, split-face trials aimed to demonstrate noninferiority of specific hyaluronic acid fillers incorporating mepivacaine (RHA-M) versus their lidocaine controls, at providing pain relief." | 5.51 | Patient Comfort, Safety, and Effectiveness of Resilient Hyaluronic Acid Fillers Formulated With Different Local Anesthetics. ( Dayan, SH; Eaton, L; Joseph, JH; Kaufman-Janette, J; Maffert, P; Smith, S, 2022) |
| " Adult patients who presented with the complaint of pain after a scorpion sting and did not have systemic findings were randomly assigned to 1 of the following 4 groups: IV paracetamol, IV dexketoprofen trometamol, topical lidocaine, and placebo." | 5.51 | Comparison of Intravenous Paracetamol, Dexketoprofen Trometamol, or Topical Lidocaine Use for Pain Relief in Scorpion Stings: A Placebo-Controlled, Randomized Study. ( Aktaş, N; Arslan, E; Aydın, İ; Gülaçtı, U; Sönmez, C; Turgut, K; Yavuz, E, 2022) |
| "Key messagesPeripheral lidocaine and oestradiol and centrally-targeted nortriptyline medications are used for the treatment of pain in women with VBD, but there is a lack of data from well-powered RCTs." | 5.51 | Rationale and design of a multicenter randomized clinical trial of vestibulodynia: understanding pathophysiology and determining appropriate treatments (vestibulodynia: UPDATe). ( Akaninwor, J; Bortsov, A; Carey, ET; Cutting, H; DeLaRosa, J; Farb, D; Geller, EJ; Luo, S; McNulty, S; Merrill, P; Nackley, AG; Rapkin, A; Stirling, C; Zakroysky, P, 2022) |
| "To compare the effect of intra-cuff lidocaine versus alkalinized lidocaine in the prevention of post-operative sore throat." | 5.51 | Comparison of intra-cuff lidocaine vs alkalinized lidocaine effects for prevention of post-operative sore throat. ( Abbas, N; Asghar, A; Hassan, SU; Naqvi, N; Rafique, M; Tariq, S, 2022) |
| "To compare the effectiveness of the topical agents in providing a more comfortable experience for the patient, allowing the practitioner to advance the endoscope with less friction, pain and discomfort for the patient using 10% lidocaine spray, 2% lidocaine gel, 4% lidocaine with xylometazoline (1:1) soaked pledgets, or aqueous gel." | 5.51 | Transnasal Flexible Laryngoscopy Using Different Topical Preparations and Methods of Application-A Randomized Study. ( Albert, RRA; Joy, AK; Mathews, SS; Philip, A, 2022) |
| "The objective of this study was to assess the efficacy of lidocaine 4% cream as pain management during immunizations and to evaluate satisfaction of caregivers and nursing staff." | 5.51 | Use of Lidocaine Cream for Pain Management During Immunizations of Infants at an Urban Health Clinic. ( Alshehry, AO; Fischetti, B; Lepa, T; Morgan, EP; Sessa, K; Valentine, M, 2022) |
| "Lidocaine cream, cryotherapy and cutaneous stimulation therapy all reduced cancer patients' pain levels during insertion of an implanted central venous access chemoport needle." | 5.51 | Comparing the effectiveness of three pain relief methods for inserting a needle into the implanted venous access chemoport: A randomized controlled trial. ( Kim, GS; Shin, J; Sim, H, 2022) |
| "Lidocaine/tetracaine 7%/7% peel cream (L/T-pC) is very effective in reducing pain in several dermatological procedures, such as hair or tattoo laser removal or conventional photodynamic therapy associated pain." | 5.51 | Assessment of clinical efficacy of lidocaine/tetracaine 7%/7% peel cream in fractional microablative laser procedure-associated pain for facial skin aging treatment. A randomized, controlled, single-blind trial. ( Caprari, E; Milani, M; Viciguerra, MT, 2022) |
| "To determine whether the addition of inhaled methoxyflurane to periprostatic infiltration of local anaesthetic (PILA) during transrectal ultrasonography-guided prostate biopsies (TRUSBs) improved pain and other aspects of the experience." | 5.51 | 'Pain-free TRUS B': a phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography-guided prostate biopsy (ANZUP 1501). ( Buchan, N; Chalasani, V; Davis, ID; Espinoza, D; Ford, KS; Frydenberg, M; Gilling, P; Gordon, B; Grummet, J; Hawks, C; Hayne, D; Konstantatos, A; Martin, AJ; McCombie, SP; Nixon, A; O'Brien, C; Patel, MI; Sengupta, S; Shahbaz, S; Stockler, MR; Subramaniam, S; Williams, S; Woo, HH, 2022) |
| " These results provide approaches to apply longer acting LA with a higher analgesic potency in an appropriate dosage and with an appropriate method of application." | 5.51 | [Pain and distress response of suckling piglets to injection and castration under local anaesthesia with procaine and licocaine - Part 2: Defence behaviour, catecholamines, coordination of movements]. ( Harlizius, J; Hofmann, K; Numberger, J; Otten, W; Rauh, A; Ritzmann, M; Scholz, T; Schulze-Horsel, T; Weiß, C; Zöls, S, 2019) |
| "Menthol inhibited phototoxicity-evoked APs and reduced pain behavior when applied topically to mice." | 5.48 | Menthol reduces phototoxicity pain in a mouse model of photodynamic therapy. ( Baptista-Hon, D; Bull, F; Dalgaty, F; Gallacher, M; Hales, TG; Ibbotson, SH; Wright, L, 2018) |
| " No systemic adverse event due to topical lidocaine were observed." | 5.46 | Lidocaine controls pain and allows safe wound bed preparation and debridement of digital ulcers in systemic sclerosis: a retrospective study. ( Bartoli, F; Braschi, F; Bruni, C; De Paulis, A; Fantauzzo, C; Fiori, G; Matucci-Cerinic, M; Paganelli, L; Rasero, L, 2017) |
| "More than 90% of spinal cord injuries are caused by traumatic accidents and are often associated with other tissue damage (polytrauma) that can provide a source of continued pain input during recovery." | 5.46 | Pain Input Impairs Recovery after Spinal Cord Injury: Treatment with Lidocaine. ( Aceves, M; Grau, JW; Hook, MA; Huang, YJ; Reynolds, JA; Strain, MM; Turtle, JD, 2017) |
| "Delirium is a common complication among hospitalized elderly individuals." | 5.43 | Delirium Associated With Lidocaine Patch Administration: A Case Presentation. ( Berry, KM; Byun, EK; Lee, A; Oh-Park, M, 2016) |
| "This was secondary analysis of prospectively obtained data from a randomized controlled trial comparing vapocoolant spray with jet-injected lidocaine for venipuncture pain." | 5.41 | An Evaluation of High Preprocedural Anxiety and Venipuncture Pain Experienced by Young Children. ( Bolin, AE; Drendel, AL; Lunoe, MM, 2021) |
| "Propofol-induced injection pain (PIP) is a well-known problem in general anesthesia." | 5.41 | Efficacy of Pre-Treatment with Remimazolam on Prevention of Propofol-Induced Injection Pain in Patients Undergoing Abortion or Curettage: A Prospective, Double-Blinded, Randomized and Placebo-Controlled Clinical Trial. ( Cao, H; Gong, X; Guan, X; Huang, X; Jiao, Z; Lan, H; Lin, C; Liu, S; Tan, Y; Xu, B, 2021) |
| "To compare the effectiveness of suppository diclofenac (100mg), cervical lidocaine 25mg -prilocaine 25mg cream (5% EMLA) and placebo in pain relief for hysterosalpingography." | 5.41 | Pain Relief for Hysterosalpingography: A Randomized Controlled, Double Blinded Trial Comparing Suppository Diclofenac, Prilocaine/Lignocaine (EMLA) Cream And Placebo. ( Agboghoroma, OC; Babandi, RM; Durojaiye, KW; Essiet, EA; Jimoh, KO, 2021) |
| " When compared to PRP, CSI with lignocaine/lidocaine had significantly higher mean difference on visual analogue scale (VAS) pain scores at 3 months (0." | 5.41 | The role of corticosteroid injections in treating plantar fasciitis: A systematic review and meta-analysis. ( Bedi, H; Bulloch, G; Gibson, D; Lower, K; Rastogi, A; Rodwell, A; Seth, I; Seth, N, 2023) |
| "The evidence is very uncertain about the effect of topical anesthetics (lidocaine) compared to no anesthesia on successful lumbar puncture on first attempt, the number of attempts per lumbar puncture, episodes of bradycardia, episodes of desaturation, and occurrence of apnea." | 5.41 | Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants. ( Bruschettini, M; Hedayati, E; Olsson, E; Pessano, S; Romantsik, O, 2023) |
| "Subcutaneous single-injection digital block with 2 ml of 1% lidocaine was highly effective in reducing pain associated with injection of corticosteroid for trigger finger." | 5.41 | Reduction in pain from corticosteroid injection for the treatment of trigger finger with subcutaneous single-injection digital block: a randomized controlled trial. ( Kosiyatrakul, A; Luenam, S; Songchou, K, 2021) |
| "10% lidocaine spray was found to be an effective local anaesthetic method for reducing pain during insertion of Cu-IUD." | 5.41 | 10% lidocaine spray for pain control during intrauterine device insertion: a randomised, double-blind, placebo-controlled trial. ( Mongkornthong, T; Panichyawat, N; Sirimai, K; Wongwananuruk, T, 2021) |
| "To determine the median effective dose (ED50) of prophylactic intravenous lidocaine for the prevention of propofol medium-chain triglyceride/long-chain triglyceride (MCT/LCT) emulsion injection pain." | 5.41 | Median Effective Dose of Lidocaine for the Prevention of Pain Caused by the Injection of Propofol Formulated with Medium- and Long-Chain Triglycerides Based on Lean Body Weight. ( Ma, R; Shan, Q; Sui, W; Tan, C; Tian, S; Xing, Z; Zhang, D; Zhang, Z; Zhou, W, 2021) |
| "To evaluate the efficacy of flushing the uterine cavity with lidocaine before hysterosalpingo-foam sonography (HyFoSy) to reduce procedure-related pain." | 5.41 | Analgesic Efficacy of Intrauterine Lidocaine Flushing in Hysterosalpingo-foam Sonography: A Double-blind Randomized Controlled Trial. ( Gal-Kochav, M; Levinsohn-Tavor, O; Maymon, R; Melcer, Y; Nimrodi, M; Pekar-Zlotin, M, 2021) |
| "To determine whether a microneedle patch combined with 5% topical lidocaine reduces dental injection pain more than a patch without microneedles combined with 5% topical lidocaine." | 5.41 | Randomised controlled trial of a microneedle patch with a topical anaesthetic for relieving the pain of dental injections. ( Addy, M; Claydon, NCA; Daly, S; Newcombe, RG; Seong, J; West, NX, 2021) |
| "Lidocaine coinfusion could effectively alleviate vascular pain induced by hypertonic saline infusion." | 5.41 | Lidocaine coinfusion alleviates vascular pain induced by hypertonic saline infusion: a randomized, placebo-controlled trial. ( Chen, S; Liao, Z; Shi, X; Song, Z; Zhang, Y; Zhao, N, 2021) |
| "In recent years, lidocaine infusion for pain management during long operations is becoming more widespread in anesthesiology practice." | 5.41 | Does intravenous lidocaine added to nonsteroidal anti-inflammatory drugs reduce pain during colposcopy? A prospective randomized double-blind study. ( Ates, I; Aydin, ME; Oral Ahiskalioglu, E; Topdagi Yilmaz, EP; Topdaği, YE, 2021) |
| "Routine use of lidocaine before esophageal function tests does not reduce pain during catheter insertion but may provide other modest benefits with limited toxicity." | 5.41 | Lidocaine before esophageal manometry and ambulatory pH monitoring: A randomized controlled trial. ( Ayuso, É; Bouin, M; Clément, M; Courbette, O; Eouani, BD; Jutras, G; Liu Chen Kiow, J; Neshkova, E; Wahba, G; Willems, P, 2021) |
| "Intent-to-treat multilevel analyses showed that for women, CBCT yielded significantly more improvements than lidocaine in pain unpleasantness at 6-month follow-up, pain anxiety and pain catastrophizing at post-treatment and 6-month follow-up, and sexual distress at post-treatment, and resulted in better treatment satisfaction and global sexuality improvements at both time points." | 5.41 | Cognitive-behavioral couple therapy versus lidocaine for provoked vestibulodynia: A randomized clinical trial. ( Bergeron, S; Corsini-Munt, S; Delisle, I; Mayrand, MH; Rosen, NO; Steben, M; Vaillancourt-Morel, MP, 2021) |
| "The purpose of this study was to compare techniques and pain scales that assess tenderness in the vulvar vestibule in provoked vestibulodynia, using the cotton swab test and a vulvalgesiometer, and assess topical lidocaine solution with each." | 5.41 | Comparing Vestibule Examination Techniques: Light Touch, Serial Forces, and the Lidocaine Test. ( Goetsch, MF; Leclair, CM; Stenson, AL, 2021) |
| " After 5 g XJ was applied to the patients, their level of lidocaine in blood was reduced to within the safe zone, and no undesirable effects were observed." | 5.38 | [Efficacy and safety of lidocaine hydrochloride jelly for the treatment of pain caused by breast cancer metastases to the skin]. ( Enomoto, T; Kikuchi, M; Kosaka, Y; Kuranami, M; Nishimiya, H; Sengoku, N; Waraya, M; Watanabe, M, 2012) |
| "Lidocaine patches are a safe, effective adjunct for rib fracture pain." | 5.37 | Lidocaine patches reduce pain in trauma patients with rib fractures. ( Mayberry, JC; Peck, EG; Schreiber, MA; Zink, KA, 2011) |
| "Spastic diplegia is present in three-fourths of children with cerebral palsy, interfering with gait and frequently accompanied by severe pain." | 5.36 | Coupled obturator neurotomies and lidocaine intrathecal infusion to treat bilateral adductor spasticity and drug-refractory pain. ( Andrade, P; Carrillo-Ruiz, JD; Castro, G; Godínez-Cubillos, N; Jiménez, F; Montes-Castillo, ML; Velasco, AL; Velasco, F, 2010) |
| "Facial burns are quite common among children." | 5.36 | Usage of lidocaine-prilocaine cream in the treatment of postburn pain in pediatric patients. ( Kargi, E; Tekerekoğlu, B, 2010) |
| "Pain was evaluated with the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS), the Visual Analogue Scale (VAS) and the Face Pain Scale (FPS) for the children and with a VAS for the parents." | 5.35 | Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children. ( Blajan, V; Brochard, S; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2009) |
| "Cold detection threshold, warm detection threshold, cold pain threshold, heat pain threshold, mechanical detection threshold, mechanical pain threshold, wind-up ratio and pressure pain threshold were assessed on the skin overlying the masseter at three consecutive days (baseline and immediately after lidocaine 4%/placebo cream)." | 5.34 | Topical anaesthesia degree is reduced in temporomandibular disorders patients: A novel approach to assess underlying mechanisms of the somatosensory alterations. ( Baad-Hansen, L; Bonjardim, LR; Conti, PCR; Costa, YM; Ferreira, DMAO; Svensson, P, 2020) |
| " Lidocaine given intravenously has been shown in two small, uncontrolled studies to have an appreciable effect on pain after burns." | 5.34 | Lidocaine infusion has a 25% opioid-sparing effect on background pain after burns: A prospective, randomised, double-blind, controlled trial. ( Abdelrahman, I; Elmasry, M; Sjoberg, F; Steinvall, I, 2020) |
| " The objective of the current study was to evaluate the effectiveness of topical lidocaine in relieving pain related to INM administration." | 5.34 | The effectiveness of topical lidocaine in relieving pain related to intranasal midazolam sedation: a randomized, placebo-controlled clinical trial. ( Khalil, W; Raslan, N, 2020) |
| "6-mL 2% lidocaine intracervical block reduces pain at tenaculum placement and levonorgestrel-releasing intrauterine system insertion among nulligravidas; and, in addition, to assess whether the intracervical block has any effect on the ease of device insertion and on the overall experience with the procedure." | 5.34 | Intracervical block for levonorgestrel-releasing intrauterine system placement among nulligravid women: a randomized double-blind controlled trial. ( Bahamondes, L; De Nadai, MN; Franceschini, SA; Juliato, CRT; Monteiro, IMU; Poli-Neto, OB; Santana, LF; Troncon, JK; Vieira, CS; Yamaguti, EMM, 2020) |
| "To compare pain control during vulvar biopsy after either application of 5% lidocaine-prilocaine cream or injection of 1% lidocaine." | 5.34 | Lidocaine-Prilocaine Cream Compared With Injected Lidocaine for Vulvar Biopsy: A Randomized Controlled Trial. ( Havrilesky, LJ; Lorenzo, A; Moss, H; Pieper, C; Weber, JM; Williams, LK, 2020) |
| "The 3P-trial has demonstrated that the preventive application of the self-occlusive lidocaine 7%-tetracaine 7% cream is very effective in reducing the procedure-associated pain during MAL-cPDT for the treatment of AK lesions." | 5.34 | Efficacy of lidocaine 7 %, tetracaine 7 % self-occlusive cream in reducing MAL-cPDT-associated pain in subjects with actinic keratosis: A randomized, single-blind, vehicle-controlled trial (The "3P-Trial"). ( Brumana, MB; Milani, M; Puviani, M, 2020) |
| "2% of subjects who were treated with HAF-Lidocaine reported reduced pain when compared with those who were treated with HAF and the mean VAS score difference was 38." | 5.34 | Reduced pain with injection of hyaluronic acid with pre-incorporated lidocaine for nasolabial fold correction: A multicenter, double-blind, randomized, active-controlled, split-face designed, clinical study. ( Choi, SY; Han, HS; Kim, BJ; Lee, JS; Lee, YW; Yoo, KH, 2020) |
| "Determine if low-dose lidocaine as a diluent during CIESI causes clinically meaningful (1) upper extremity weakness and (2) immediate pain relief when compared with saline." | 5.34 | Effect of low-dose lidocaine on objective upper extremity strength and immediate pain relief following cervical interlaminar epidural injections: a double-blinded randomized controlled trial. ( Bougie, D; Burnham, T; Cunningham, S; Kendall, RW; McCormick, ZL; Teramoto, M; Walega, DR, 2020) |
| " The toxic reactions associated with an accidental overdose have been reported in pediatric cases." | 5.31 | Lidocaine toxicity during frequent viscous lidocaine use for painful tongue ulcer. ( Kakiuchi, Y; Miyabe, M; Sato, S; Yamaguchi, H; Yamashita, S, 2002) |
| "Intraurethral administration of 4% lidocaine did not decrease VE compared to placebo and did not change pain scores following catheterization." | 5.30 | Randomized Controlled Trial to Assess the Impact of High Concentration Intraurethral Lidocaine on Urodynamic Voiding Parameters. ( Amundsen, CL; Gonzalez, EJ; Grill, WM; McKee, DC, 2019) |
| "We compared the analgesic effects of intravenous (IV) lidocaine and IV morphine for the treatment of severe pain in the emergency department (ED)." | 5.30 | Intravenous Lidocaine Provides Similar Analgesia to Intravenous Morphine for Undifferentiated Severe Pain in the Emergency Department: A Pilot, Unblinded Randomized Controlled Trial. ( Clattenburg, EJ; Flores, S; Hailozian, C; Herring, AA; Louie, D; Nguyen, A; Yoo, T, 2019) |
| "One hundred six adult patients with symptomatic irreversible pulpitis in a mandibular first or second molar received an initial inferior alveolar nerve block with 2% lidocaine with 1:80,000 epinephrine." | 5.30 | Efficacy of Articaine Versus Lidocaine Administered as Supplementary Intraligamentary Injection after a Failed Inferior Alveolar Nerve Block: A Randomized Double-blind Study. ( Aggarwal, V; Kohli, S; Miglani, S; Singla, M, 2019) |
| "To determine the effect of cold therapy, music therapy and lidocaine spray on pain and anxiety following chest tube removal (CTR)." | 5.30 | The use of cold therapy, music therapy and lidocaine spray for reducing pain and anxiety following chest tube removal. ( Aktaş, YY; Karabulut, N, 2019) |
| "To determine the analgesic efficacy and analgesic duration of lidocaine 20 mg and 40 mg on eliminating the vascular pain associated with hypertonic saline infusion." | 5.30 | The analgesic efficacy and duration of lidocaine on vascular pain induced by hypertonic saline infusion: a double-blinded, randomized control trial. ( Liu, Z; Song, Z; Zhang, Y, 2019) |
| "To evaluate Neosaxitoxin (NeoSTX) as a local anesthetic drug, for pain control during and after piglet castration." | 5.30 | Evaluation of Neosaxitoxin as a local anesthetic during piglet castration: A potential alternative for Lidocaine. ( Bustamante, T; Del Campo, M; Lagos, N; Muñoz, V; Piron, R; Sánchez, A; Sepúlveda, JM; Simbaina, JC; Torres, C; Valenzuela, C, 2019) |
| "To evaluate the effect of doxepin mouthwash or diphenhydramine-lidocaine-antacid mouthwash for the treatment of oral mucositis-related pain." | 5.30 | Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial. ( Curtis, A; Ko, SJ; Le-Rademacher, JG; Leenstra, JL; Loprinzi, CL; Martenson, JA; Miller, RC; Novotny, PJ; Qin, R; Reiter, PL; Rine, G; Singh, AK; Sio, TT; Tan, AD, 2019) |
| "Pain levels are generally low for MRI-guided in-bore biopsy using either PPNB or intrarectal instillation of lidocaine gel." | 5.30 | Comparison of analgesic techniques in MRI-guided in-bore prostate biopsy. ( Albers, P; Antoch, G; Arsov, C; Blondin, D; Hiester, A; Quentin, M; Schimmöller, L; Ullrich, T; Valentin, B, 2019) |
| "To compare the safety and efficacy of xylocaine gel and ketorolac as opioid-sparing analgesia compared with pethidine for shock wave lithotripsy (SWL) pain." | 5.30 | Efficacy of pethidine, ketorolac, and lidocaine gel as analgesics for pain control in shockwave lithotripsy: A single-blinded randomized controlled trial. ( Abol-Enein, H; Atwa, AM; El-Assmy, A; Elbaset, MA; Fadallah, M; Ghobrial, FK; Hashem, A; Laymon, M; Sheir, KZ, 2019) |
| "Lidocaine alleviates propofol injection pain." | 5.27 | Intravenous Lidocaine Alleviates the Pain of Propofol Injection by Local Anesthetic and Central Analgesic Effects. ( Cai, J; Hei, Z; Liang, L; Luo, C; Xing, J; Zhou, S, 2018) |
| "05 mol/L GABA, 1% lidocaine) was investigated for the amelioration of pain and sensitivity induced by application of capsaicin (1%, 2 min) to the tongue of thirty healthy male and female subjects in this four-session, randomized, placebo-controlled, double-blinded, cross-over study." | 5.27 | γ-Aminobutyric acid (GABA) oral rinse reduces capsaicin-induced burning mouth pain sensation: An experimental quantitative sensory testing study in healthy subjects. ( Arendt-Nielsen, L; Cairns, BE; Wang, K; Zhang, Y, 2018) |
| " An open, randomized, prospective, longitudinal, comparative, and experimental clinical study was conducted to evaluate the efficacy of subcostal nerve block with lidocaine, comparing it in combination with tramadol or diclofenac for pain control during ESWL." | 5.27 | Comparison of three analgesic drug regimens with twelfth subcostal nerve block for pain control during extracorporeal shock wave lithotripsy. ( Del Rosario-Santiago, M; Garduño-Arteaga, LM; Jaspersen-Gastelum, J; Maldonado-Avila, M; Rios-Davila, V; Vela-Mollinedo, RA; Virgen-Gutierrez, F, 2018) |
| "Intraurethral lidocaine for TUBC for urine collection using a blunt tipped applicator did not improve procedural pain scores." | 5.27 | Randomized Clinical Trial of Lidocaine Analgesia for Transurethral Bladder Catheterization Delivered via Blunt Tipped Applicator in Young Children. ( Bradford, MC; Colton, TL; Follmer, K; Gritton, J; Klein, EJ; Merguerian, PA; Strelitz, B; Uspal, NG, 2018) |
| "The aim of the study was to compare the effectiveness of pain control between lidocaine spray (LS) and paracervical block (PB) with lidocaine during the loop electrosurgical excision procedure (LEEP)." | 5.27 | Lidocaine Spray Versus Paracervical Block During Loop Electrosurgical Excision Procedure: A Randomized Trial. ( Buapaichit, K; Chalapati, W; Limwatanapan, N; Saenpoch, S; Songthamwat, M; Songthamwat, S, 2018) |
| "To compare the anaesthetic efficacy for pain and behaviour during treatment with mandibular infiltration using 4% articaine (BI) with inferior dental nerve clock (IDNB) using 2% lidocaine for extraction or pulp therapy in mandibular primary molars." | 5.27 | Anaesthetic efficacy of 4% articaine and 2% lidocaine for extraction and pulpotomy of mandibular primary molars: an equivalence parallel prospective randomized controlled trial. ( Alzahrani, F; Duggal, MS; Munyombwe, T; Tahmassebi, JF, 2018) |
| "Lidocaine is used to alleviate procedural pain but paradoxically increases pain during injection." | 5.27 | Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial. ( Doman, ER; Hall, JB; Kress, JP; Patel, BK; Patel, SB; Pohlman, AS; Wendlandt, BN; Wolfe, KS, 2018) |
| " A combination of xylocaine and bupivacaine is recommended to overcome the accompanying pain of the procedure." | 5.27 | Syringes versus Chinese cups in harvesting suction-induced blister graft: a randomized split-body study. ( Abdel-Rahman, AT; Anbar, TS; El-Fakahany, HM; El-Khayyat, MAM; Moftah, NH; Saad, EK, 2018) |
| "Prehospital management of traumatic pain is commonly based on morphine while locoregional analgesia techniques, especially the femoral nerve block (FNB), can be safely and efficiently used." | 5.27 | Magnesium Sulfate as Adjuvant in Prehospital Femoral Nerve Block for a Patient with Diaphysial Femoral Fracture: A Randomized Controlled Trial. ( Chebili, N; Ferhi, F; Hassine, N; Jaouadi, MA; Jebali, C; Kahloul, M; Naija, W, 2018) |
| "Nociceptive thresholds and supra-threshold pain ratings as well as their reduction upon local injection with lidocaine were compared between healthy subjects and patients with erythromelalgia (EM)." | 5.24 | Pain thresholds, supra-threshold pain and lidocaine sensitivity in patients with erythromelalgia, including the I848Tmutation in Na ( Helås, T; Jönsson, B; Jørum, E; Kleggetveit, IP; Quiding, H; Sagafos, D; Salter, H; Schmelz, M; Segerdahl, M; Zhang, Z, 2017) |
| " The aim of this study is to investigate the combined effect of intraurethral lidocaine gel and intraglandular injection of lidocaine 2% on pain during and after cystoscopy." | 5.24 | A Randomized Control Trial Comparing Combined Glandular Lidocaine Injection and Intraurethral Lidocaine Gel with Intraurethral Lidocaine Gel Alone in Cystoscopy and Urethral Dilatation. ( Bahrami, S; Behtash, N; Fakhr Yasseri, AM; Gooran, S; Javid, A; Pourfakhr, P; Pourmand, G, 2017) |
| "Local anaesthesia with 1-2 ml lidocaine at subcutaneous fat level reduced pain and provided optimal image quality in direct shoulder magnetic resonance arthrography." | 5.24 | Direct shoulder magnetic resonance arthrography for superior labral anterior-to-posterior (SLAP) and Bankart lesions: investigation into the appropriate dose and level of local anesthesia. ( Jo, HH; Kim, DH; Lee, SH; Park, YS; Song, JG; Yun, SJ, 2017) |
| "Propofol causes injection pain." | 5.24 | Preventive effect of a vapocoolant spray on propofol-induced pain: a prospective, double-blind, randomized study. ( Kim, DH; Lee, MY; Moon, YE, 2017) |
| "A randomized, controlled trial of fully factorial design was performed to study pain during venipuncture after local anesthesia either with intra - dermally injected lidocaine or with a vapocoolant spray, in comparison to placebo." | 5.24 | Pain During Venous Cannulation. ( Hj Eberhart, L; Koch, T; Rüsch, D; Spies, M, 2017) |
| "Neonatal Infant Pain Scale scores were significantly lower in the intervention groups (EMLA + sucrose, mean [SD]: 3." | 5.24 | Combination Analgesia for Neonatal Circumcision: A Randomized Controlled Trial. ( Charafeddine, L; El-Hout, Y; Lakissian, Z; Milad, N; Sharara-Chami, R, 2017) |
| " The purpose of this study was to determine the influence of lidocaine temperature on pain during subcutaneous injection." | 5.24 | The influence of Lidocaine temperature on pain during subcutaneous injection. ( Ballo, S; Finsen, V; Foss, OA; Hjelseng, T; Lundbom, JS; Skarsvåg, TI; Tangen, LF; Wågø, KJ, 2017) |
| "Local infiltration with lidocaine is a frequently used measure to prevent pain during arterial cannulation." | 5.24 | Vapocoolant Spray Versus Lidocaine Infiltration for Radial Artery Cannulation: A Prospective, Randomized, Controlled Clinical Trial. ( Eberhart, L; Koch, T; Rüsch, D; Seel, F, 2017) |
| "The objective was to investigate the analgesic effect of cervical lidocaine-prilocaine (LP) cream in alleviating pain during copper T380A intrauterine device (IUD) insertion among parous women." | 5.24 | Effect of cervical lidocaine-prilocaine cream on pain perception during copper T380A intrauterine device insertion among parous women: A randomized double-blind controlled trial. ( Abbas, AM; Abdellah, MS; Abdellah, NH; Abdelmagied, AM; Ali, MK; Bahloul, M; Khalaf, M, 2017) |
| "To assess efficacy of two different techniques of lidocaine injection in the uterine arteries to reduce pain following uterine artery embolization (UAE) for leiomyomas." | 5.24 | Intraarterial Lidocaine for Pain Control in Uterine Artery Embolization: A Prospective, Randomized Study. ( Mironov, O; Noel-Lamy, M; Rajan, DK; Simons, ME; Sniderman, KW; Tan, KT, 2017) |
| "To study the benefit of applying topical anesthetics or a 1:1 mixture of 1% lidocaine and TA at the TA injection site to alleviate pain during keloid treatment." | 5.24 | A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial. ( Burusapat, C; Usanakornkul, A, 2017) |
| "4% articaine BI showed comparable results in terms of pain relief and success rate in comparison with 2% lidocaine IANB or 4% articaine IANB." | 5.22 | EFFICACY OF 4% ARTICAINE BUCCAL INFILTRATION VERSUS INFERIOR ALVEOLAR NERVE BLOCK FOR MANDIBULAR MOLARS WITH SYMPTOMATIC IRREVERSIBLE PULPITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. ( Abuiriban, RW; Al-Hamed, FS; Almadhoon, HW; Almassri, H, 2022) |
| " The network meta-analysis revealed that "bicarbonate-buffered lidocaine with epinephrine" led to a significant decrease in injection pain (preference question) compared to "prilocaine with felypressin" and "lidocaine with epinephrine," whereas no significant differences were detected in the analysis of injection pain measured using the VAS." | 5.22 | Patient Comfort with Various Local Infiltration Anesthetics for Minor Oculoplastic Surgery: A Systematic Review and Network Meta-Analysis. ( Chen, C; Chiu, WK; Kang, YN; Liou, CM; Liu, HM; Wu, TJ, 2022) |
| "Intra-articular lidocaine may have similar effectiveness as IV sedation in the successful reduction of anterior shoulder dislocations in the ED with fewer adverse events, shorter ED length of stay, and no difference in pain scores or ease of reduction." | 5.22 | Intra-articular lidocaine versus intravenous sedation for closed reduction of acute anterior shoulder dislocation in the emergency department: a systematic review and meta-analysis. ( Grewal, K; McLeod, S; Sithamparapillai, A; Thompson, C; Walsh, C, 2022) |
| "The purpose of this study was to determine the effectiveness of topical liposomal lidocaine in reducing the pain perceived by children undergoing percutaneous intraosseous pin (PP) removal in the outpatient orthopaedic clinic." | 5.22 | Does Topical Anesthetic Reduce Pain During Intraosseous Pin Removal in Children? A Randomized Controlled Trial. ( Al-Mansoori, K; Beaupre, LA; Cave, D; Dulai, SK; Firth, K; Kemp, KA; Saraswat, MK; Silveira, A, 2016) |
| "Significant pain reduction during IUD insertion can be achieved by using 10% lidocaine spray alone." | 5.22 | Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial. ( Açmaz, G; Aksoy, H; Aksoy, Ü; Babayigit, M; Ozyurt, S, 2016) |
| "The objective of this study was to evaluate the efficacy of bilateral endoscopic injection of lidocaine with epinephrine in the sphenopalatine ganglion at the end of endoscopic sinus surgery (ESS) in controlling postoperative pain and rescue analgesic requirements." | 5.22 | Endoscopic sphenopalatine ganglion blockade efficacy in pain control after endoscopic sinus surgery. ( Al-Qudah, M, 2016) |
| "Administration of 300 mg MgSO4 plus 40 mg lidocaine reduces propofol injection pain very well." | 5.22 | Magnesium Sulfate Plus Lidocaine Reduces Propofol Injection Pain: A Double-blind, Randomized Study. ( Lin, W; Sun, J; Wang, W; Zhou, J; Zhou, R, 2016) |
| "To evaluate the efficacy of topical lidocaine 2% gel in reducing the pain associated with the insertion of nasal continuous positive airway pressure (nCPAP) prongs in preterm infants." | 5.22 | Does Topical Lidocaine Reduce the Pain Associated With the Insertion of Nasal Continuous Positive Airway Pressure Prongs in Preterm Infants?: A Randomized, Controlled Pilot Trial. ( Abdel-Hady, H; Elsharkawy, A; Soliman, H, 2016) |
| "Research on the safety and efficacy of continuous lidocaine infusions (CLIs) for the treatment of pain in the pediatric setting is limited." | 5.22 | Continuous Lidocaine Infusions to Manage Opioid-Refractory Pain in a Series of Cancer Patients in a Pediatric Hospital. ( Beckman, EJ; DeMonbrun, A; Gibbons, K; Hakel, S; Keefer, P; Liu, M; Niedner, M; Saul, D; Stewart, M; Wagner, D, 2016) |
| "To determine the effectiveness of diclofenac potassium combined with 2% lidocaine gel in reducing the pain of intrauterine device (IUD) insertion." | 5.22 | Diclofenac plus lidocaine gel for pain relief during intrauterine device insertion. A randomized, double-blinded, placebo-controlled study. ( Elsetohy, KA; Fouda, UM; Salah Eldin, NM; Shaban, MM; Sobh, SM; Tolba, HA, 2016) |
| "Premedication with 2 mg of IV midazolam reduces pain of NGT insertion in ED patients without the need for full procedural sedation." | 5.22 | Does Routine Midazolam Administration Prior to Nasogastric Tube Insertion in the Emergency Department Decrease Patients' Pain? (A Pilot Study). ( Buinewicz, JD; Freeman, K; Gutierrez, K; Manning, CT; O'Keefe, MF; Sewatsky, TP; Zgonis, E, 2016) |
| "Injecting lidocaine by jet injector is less painful than infiltrating it by needle and syringe." | 5.22 | Comparison of local anesthetic effect of lidocaine by jet injection vs needle infiltration in lumbar puncture. ( Arabinejhad, A; Hajimaghsoudi, M; Momeni, M; Saeedi, M; Vahidi, E, 2016) |
| "The combination of ibuprofen/paracetamol, taken immediately after initial endodontic therapy and root canal preparation in teeth with irreversible pulpitis, reduced post-endodontic pain (ClinicalTrials." | 5.22 | Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain. ( Abubakr, NH; Elzaki, WM; Ibrahim, YE; Ziada, HM, 2016) |
| "The combination of 240 mg of intravenous lidocaine (once a week for 4 weeks) with 25 mg of amitriptyline for 8 weeks had no meaningful impact in fibromyalgia patients." | 5.22 | Effect of intravenous lidocaine combined with amitriptyline on pain intensity, clinical manifestations and the concentrations of IL-1, IL-6 and IL-8 in patients with fibromyalgia: A randomized double-blind study. ( Albertoni Giraldes, AL; Brunialti, MK; Leal, PD; Sakata, RK; Salomão, R, 2016) |
| "Lidocaine reduces pain that occurs upon the intravenous injection of propofol." | 5.22 | Comparison of the effects of lidocaine pre-administration and local warming of the intravenous access site on propofol injection pain: Randomized, double-blind controlled trial. ( Jeong, M; Yoon, H, 2016) |
| "To compare pain control at various time points during first-trimester surgical abortion using a patient-administered lidocaine gel compared with a traditional lidocaine paracervical block." | 5.22 | Self-Administered Lidocaine Gel for Pain Control With First-Trimester Surgical Abortion: A Randomized Controlled Trial. ( Blumenthal, PD; Conti, JA; Lerma, K; Shaw, KA, 2016) |
| "To evaluate self-administration of vaginal lidocaine gel to decrease pain with intrauterine device (IUD) insertion in nulliparous women." | 5.22 | Self-Administered Lidocaine Gel for Intrauterine Device Insertion in Nulliparous Women: A Randomized Controlled Trial. ( Achilles, SL; Boraas, CM; Chen, BA; Cremer, M; Meyn, L; Rapkin, RB; Schwarz, EB, 2016) |
| "Although liposomal bupivacaine had some effect on soft tissue anesthesia, it did not reduce pain to manageable clinical levels in patients presenting with untreated, symptomatic irreversible pulpitis." | 5.22 | Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial. ( Beck, M; Bultema, K; Drum, M; Fowler, S; Nusstein, J; Reader, A, 2016) |
| "Pretreatment with oral pregabalin 150 mg and intravenous lidocaine 40 mg with venous occlusion equally reduced pain from propofol injection." | 5.22 | Comparative study between 2 different doses of pregabalin and lidocaine on pain following propofol injection: A double-blind, randomized clinical consort study. ( Choi, E; Jeon, Y; Kim, D, 2016) |
| "To compare the pain perception between intraurethral instillation of 2% lidocaine gel and liquid paraffin during Urodynamic study in men." | 5.20 | Liquid paraffin is superior to 2% lidocaine gel in reducing urethral pain during urodynamic study in men: A pilot study. ( Beberashvili, I; Sabler, IM; Siegel, YI; Stav, K; Taleb, E; Zisman, A, 2015) |
| "The incidence of propofol injection pain is high in children, but no methods have been found to suppress it completely." | 5.20 | Preemptive dexmedetomidine to prevent propofol injection pain in children. ( Dong, C; Lu, Y; Yu, J; Zhang, Y, 2015) |
| "In this double-blind, placebo-controlled, randomized trial, the combination of intravenous magnesium sulfate and lidocaine offered no additional benefit for the relief of propofol injection pain compared to intravenous lidocaine alone." | 5.20 | Magnesium sulfate with lidocaine for preventing propofol injection pain: a randomized, double-blind, placebo-controlled trial. ( Galgon, RE; Groth, J; Heier, J; Schroeder, KM; Strube, P; Wang, S, 2015) |
| "To compare the effectiveness of intravenous lidocaine and intravenous morphine in decreasing pain in patients with critical limb ischaemia." | 5.20 | Comparison of intravenous lidocaine versus morphine in alleviating pain in patients with critical limb ischaemia. ( Aghaie Meybodi, M; Saeedi, M; Shakoor, D; Vahidi, E, 2015) |
| " Significant reduction in pain intensity was observed with topical lidocaine group when compared with the ice application group (p < 0." | 5.20 | A randomized trial comparing intravenous paracetamol, topical lidocaine, and ice application for treatment of pain associated with scorpion stings. ( Aksel, G; Çorbacioğlu, ŞK; Doğan, NÖ; Güler, S, 2015) |
| "The purpose of this prospective, randomized, double-blind study was to compare the anesthetic efficacy of buffered with nonbuffered 2% lidocaine with 1:80,000 epinephrine solution for inferior alveolar nerve (IAN) block in patients with mandibular posterior teeth experiencing symptomatic irreversible pulpitis." | 5.20 | Effect of sodium bicarbonate-buffered lidocaine on the success of inferior alveolar nerve block for teeth with symptomatic irreversible pulpitis: a prospective, randomized double-blind study. ( Baghaei, B; Khademi, A; Noormohammadi, H; Saatchi, M, 2015) |
| " Pain relief was observed with lidocaine vs." | 5.20 | Novel topical formulation of lidocaine provides significant pain relief for intrauterine device insertion: pharmacokinetic evaluation and randomized placebo-controlled trial. ( Conner, P; Ekman-Ordeberg, G; Liliecreutz, C; Tingåker, BK; Tornblom-Paulander, S; Werner, A; Wessel, H, 2015) |
| "This study aims to analyze the efficiency of EMLA cream and ethyl chloride spray application for pain alleviation before botulinum toxin injection." | 5.20 | A Clinical Comparison of EMLA Cream and Ethyl Chloride Spray Application for Pain Relief of Forehead Botulinum Toxin Injection. ( Irkoren, S; Karaca, H; Ozkan, HS, 2015) |
| " Addition of sodium bicarbonate lowers the acidity of anesthetic solutions, which might cause less pain." | 5.20 | Prospective study of a single treatment strategy for local tumescent anesthesia in Muller phlebectomy. ( Bouwman, LH; Dekkers, P; Krasznai, AG; Sigterman, TA; Sikkink, CJ; Snoeijs, MG; Willems, CE; Wittens, CH, 2015) |
| "Alkalinized lidocaine and heparin have been reported to provide relief from pain and urgency symptoms associated with IC." | 5.20 | Heparin and alkalinized lidocaine versus alkalinized lidocaine for treatment of interstitial cystitis symptoms. ( Argade, S; Koziol, JA; Parsons, CL; Proctor, JG; Zupkas, P, 2015) |
| "Hyaluronic acid (HA) fillers are sometimes mixed with lidocaine to mitigate pain." | 5.20 | A blinded, randomized, split-face pilot study of bruising and pain with hyaluronic acid for correction of perioral lines using no lidocaine, lidocaine alone, and lidocaine and epinephrine. ( Howell, DJ; Moradi, A; Moradi-Poehler, J; Shirazi, A; Turner, J, 2015) |
| "To evaluate the efficacy of tramadol, lidocaine, and a combination of tramadol with lidocaine in pain relief using periprostatic nerve block technique by guidance of transrectal ultrasound (TRUS) before the prostate biopsy (PBx)." | 5.20 | Combination of Tramadol and Lidocaine for Pain Control During Transrectal Ultrasound-guided Prostate Biopsy: A Randomized Double-blinded Study. ( Bayrak, O; Erturhan, S; Seckiner, I; Sen, E; Sen, H; Yagci, F, 2015) |
| "Pre-cooling could induce similar injection pain relief to that of buffered lidocaine while maintaining longer postoperative anesthetic results than buffered lidocaine." | 5.20 | Prospective evaluation of pain and follow-up results when pre-cooling skin versus buffering lidocaine for upper blepharoplasty. ( Huang, L, 2015) |
| "To determine whether lidocaine is superior to nonanesthetic lubricant (NAL) for relieving pain in children undergoing urethral catheterization (UC)." | 5.20 | Intraurethral Lidocaine for Urethral Catheterization in Children: A Randomized Controlled Trial. ( Ali, S; Castelo, M; Gerges, S; Langford, C; Lepore, N; Li, J; Manji, K; Matsui, D; Poonai, N; Qui, T; Rieder, M; Stitt, L; Taddio, A; Teefy, J, 2015) |
| "We aimed to compare the effectiveness of esmolol 1 mg/kg and lidocaine 1 mg/kg for injection pain and for the prevention of rocuronium-induced withdrawal response." | 5.20 | Effects of pretreatment with esmolol and lidocaine on injection pain and rocuronium-induced withdrawal response. ( Akinci, M; Bumin Aydin, G; Ergil, J; Gürel, A; Kavak Akelma, F; Özkan, D, 2015) |
| "The results of our study showed that lidocaine puffs provided the best pain relief than the other analgesics used." | 5.20 | Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, pethidine & diclofenac sodium application for pain relief during fractional curettage: A randomized controlled trial. ( Acmaz, G; Aksoy, H; Başer, M; Bayraktar, E; Müderris, İİ; Yilmaz, MO, 2015) |
| " Subcutaneously injected lidocaine anesthesia did not reduce the median pain of radial artery puncture (control 1." | 5.20 | Radial artery blood gas sampling: a randomized controlled trial of lidocaine local anesthesia. ( Crawfurd, J; Holland, R; Wade, D; Wade, RG, 2015) |
| "Our study evaluated whether buffering reduces pain from lidocaine injection for loop electrosurgical excisional procedures (LEEPs) of the cervix when compared to unbuffered lidocaine." | 5.19 | A randomized trial of buffered versus nonbuffered lidocaine with epinephrine for cervical loop excision. ( Ioffe, Y; Kizer, NT; Massad, LS; Peipert, JF; Zhao, Q, 2014) |
| "The aim of this study was to assess the efficacy in pain reduction of topical 2 % lidocaine compared to a placebo cream in children with oral mucosal lesions due to trauma or aphthous ulcers or in the prevention of clamp placement pain." | 5.19 | Phase III, randomized, double-blind, placebo-controlled trial of topical 2 % lidocaine for the prevention and treatment of oral mucosal pain in children. ( Artaud, C; Baaroun, V; Coudert, AE; Descroix, V; Druo, JP; Ifi-Naulin, C; Ostertag, A; Princ, G, 2014) |
| "To determine optimum duration of intraurethral 2% lidocaine jelly for pain relief during outpatient rigid cystoscopy." | 5.19 | Effect of intraurethral dwell time of local anesthetic jelly on pain perception in men undergoing outpatient rigid cystoscopy: a randomized prospective study. ( Jha, SK; Kumar, A; Kumar, N; Kumar, R; Mohanty, A; Nanda, B; Singh, H; Vasudeva, P, 2014) |
| "To investigate the efficacy of pretreatment with cisatracurium for prevention of pain associated with propofol injection, and compare its efficacy with that of lidocaine." | 5.19 | Cisatracurium pretreatment with tourniquet reduces propofol injection pain: a double-blind randomized controlled trial. ( Kim, YH; Lim, CH; Namgung, J, 2014) |
| "5 mg/kg lidocaine with venous occlusion is recommended to prevent pain following injection of lipid emulsion propofol." | 5.19 | Intravenous lidocaine pretreatment with venous occlusion for reducing microemulsion propofol induced pain: comparison of three doses of lidocaine. ( Chae, YJ; Chang, HS; Joe, HB; Kim, DH; Kim, JA, 2014) |
| "This study used a 60-s venous occlusion technique to evaluate the effectiveness of pretreatment with lidocaine, fentanyl, or remifentanil in preventing pain-induced withdrawal caused by intravenous injection of rocuronium bromide during the induction of general anesthesia." | 5.19 | Pretreatment with remifentanil, fentanyl, or lidocaine to prevent withdrawal after rocuronium using venous occlusion technique in children and adolescents: a prospective randomized placebo-controlled double-blind study. ( Abu-Halaweh, AS; Abu-Halaweh, SA; Al Zaben, KR; Al-Hussami, MO; Aloweidi, AK; Qudaisat, IY, 2014) |
| "We studied the analgesia provided by a lidocaine/tetracaine patch compared to injectable lidocaine during incision and drainage (I&D) of skin abscesses." | 5.19 | Injectable lidocaine provides similar analgesia compared to transdermal lidocaine/tetracaine patch for the incision and drainage of skin abscesses: a randomized, controlled trial. ( Bourne, CL; Brewer, KL; House, J, 2014) |
| " Before fracture reduction, children 3 to 17 years of age randomly received 2% lidocaine (L) or normal saline (NS) into the hematoma of their fracture site during sedation with intravenous ketamine and midazolam." | 5.19 | Evaluating the hematoma block as an adjunct to procedural sedation for closed reduction of distal forearm fractures. ( Constantine, E; Eberson, CP; Linakis, JG; Machan, JT; Steele, DW; Tsze, DS, 2014) |
| "In a double-blind, multisite trial, we randomly assigned 400 patients who had lumbar central spinal stenosis and moderate-to-severe leg pain and disability to receive epidural injections of glucocorticoids plus lidocaine or lidocaine alone." | 5.19 | A randomized trial of epidural glucocorticoid injections for spinal stenosis. ( Akuthota, V; Annaswamy, T; Avins, AL; Bauer, Z; Bresnahan, BW; Chen, A; Comstock, BA; Deyo, RA; Diehn, F; Firtch, W; Friedly, JL; Gerges, FJ; Gilligan, C; Goldberg, H; Heagerty, PJ; Jarvik, JG; Kennedy, DJ; Kessler, L; Mandel, S; Nedeljkovic, SS; Nerenz, DR; Sanders, W; Sibell, D; Smuck, M; Standaert, C; Sullivan, SD; Turner, JA; Tyburski, M; Wasan, A; Won, L, 2014) |
| "We designed the present study to determine whether JetPeel™-3, a medical device used for transdermal delivery of drugs by jet nebulization, could be used to deliver lidocaine prior to the standard multiple BTX-A injections or deliver lidocaine together with BTX-A in order to determine the protocol giving better results in terms of procedure-related pain, sweating, and patient satisfaction in subjects affected by primary axillary, palmar or plantar hyperhidrosis." | 5.19 | A preliminary study of painless and effective transdermal botulinum toxin A delivery by jet nebulization for treatment of primary hyperhidrosis. ( Aspiro, A; Di Cerbo, A; Iannitti, T; Palmieri, B, 2014) |
| "To determine if intrauterine administration of 5 cc of 2% lidocaine in addition to paracervical block reduces pain during laminaria insertion, when compared with paracervical block and saline placebo." | 5.19 | Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial. ( Liberty, A; Mercier, RJ, 2014) |
| "The combination of 3% mepivacaine plus 2% lidocaine with 1:100,000 epinephrine was equivalent to the combination of 2 cartridges of 2% lidocaine with 1:100,000 epinephrine in terms of injection pain, onset time, and pulpal anesthetic success for the IAN block." | 5.19 | Does the combination of 3% mepivacaine plain plus 2% lidocaine with epinephrine improve anesthesia and reduce the pain of anesthetic injection for the inferior alveolar nerve block? A prospective, randomized, double-blind study. ( Beck, M; Drum, M; Fowler, S; Lammers, E; Nusstein, J; Reader, A, 2014) |
| "The incidence of propofol-induced pain was significantly higher in the control group (39%) than in the other three groups (17% in the cooling group, 16% in the lidocaine group and 8% in the lidocaine plus cooling group)." | 5.19 | [Effectiveness of local cooling and lidocaine administration for prevention of pain upon injection of propofol]. ( Fujinaka, W; Takatori, M; Takubo, I; Terada, N, 2014) |
| "The results from our study indicate that injecting subcutaneous buffered lidocaine before intradermal injection of (99m)Tc-SC for breast lymphoscintigraphy significantly decreases patient pain without interfering with lymph node visualization." | 5.19 | Administration of subcutaneous buffered lidocaine prior to breast lymphoscintigraphy reduces pain without decreasing lymph node visualization. ( Baird, GL; Hawkins, AS; Movson, JS; Noto, RB; Powers, K; Yoo, DC, 2014) |
| "Between January 2006 and April 2009, 140 patients with early breast cancer were randomly assigned (1:1:1:1) to receive standard topical 4 % lidocaine cream and intradermal Tc-99m (control) or to one of three other study groups: topical placebo cream and injection of Tc-99m containing sodium bicarbonate (NaHCO3), 1 % lidocaine, or both." | 5.17 | Technical effects of adding 1 % lidocaine to technetium sulfur colloid for sentinel lymphatic mapping in early breast cancer: analysis of data from a double-blind randomized controlled trial. ( Arciero, CA; Avital, I; Bilchik, AJ; Buckenmaier Iii, CC; Henry, LR; Howard, RS; Peoples, GE; Stojadinovic, A, 2013) |
| "The authors tested the primary hypothesis that perioperative IV lidocaine administration during spine surgery (and in the postanesthesia care unit for no more than 8 h) decreases pain and/or opioid requirements in the initial 48 postoperative hours." | 5.17 | Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery. ( Benzel, E; Bingaman, W; Dalton, JE; Farag, E; Ghobrial, M; Kurz, A; Lee, JH; Liu, J; Sessler, DI; Zaky, S, 2013) |
| "We investigated the efficacy of 5% lidocaine 25 mg-prilocaine 25 mg/g cream (EMLA(®) ) applied to the uterine cervix for reducing pain during diagnostic or operative hysteroscopy, using a visual analogue scale (VAS) for pain in a prospective randomized, non-blinded, controlled study in 92 successive patients." | 5.17 | Lidocaine-prilocaine (EMLA(®) ) cream as analgesia in hysteroscopy practice: a prospective, randomized, non-blinded, controlled study. ( Arnau, B; Canals, M; Jiménez, E; Jovell, E; Mir, V; Redón, S, 2013) |
| "The aim of this study was to determine whether pretreatment with alkalinised lignocaine reduced the incidence and severity of pain during propofol injection." | 5.17 | Effect of alkalinisation of lignocaine for propofol injection pain: a prospective, randomised, double-blind study. ( Aydogan, MS; Begec, Z; Colak, C; Erdogan, MA; Ozgul, U; Sanli, M, 2013) |
| "The combination of periprostatic nerve blockade and intrarectal lidocain gel provides a more meaningful pain relief compared to group of patients undergoing intrarectal lidocaine gel." | 5.17 | The effectivity of periprostatic nerve blockade for the pain control during transrectal ultrasound guided prostate biopsy. ( Besiroglu, H; Cakir, SS; Can Polat, E; Dursun, M; Karadeniz, T; Otunctemur, A; Ozbek, E, 2013) |
| "The study aimed to evaluate the effects of the pretreatment with lidocaine, fentanyl, and remifentanil using a venous occlusion technique in preventing pain caused by intravenous injection of rocuronium during induction of general anesthesia." | 5.17 | Comparison of three methods of preventing rocuronium induced pain on injection using venous occlusion technique: a randomized prospective double blind controlled study. ( Abu-Halaweh, NS; Abu-Halaweh, SA; Al-Hussami, MO; Al-Mustafa, M; Aloweidi, AK; Atyat, BS; Qudaisat, IY, 2013) |
| " There was a significantly lower mean pain score due to probe insertion in those patients who received topical diltiazem than in the placebo group (p<0." | 5.17 | Evaluation of the efficacy of a combination of diltiazem and periprostatic nerve block in pain control during transrectal ultrasonography-guided biopsy of the prostate. ( Biswas, G; Jindal, T; Karmakar, D; Mandal, SN, 2013) |
| "Treating minor lacerations with lidocaine-epinephrine-tetracaine before wound closure with tissue adhesive reduced ratings of pain and increased the proportion of pain-free repairs among children aged 3 months to 17 years." | 5.17 | Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children: a randomized controlled trial. ( Duncan, MJ; Harman, S; Petrcich, W; Ying, Y; Zemek, R, 2013) |
| "Lidocaine spray is an effective and practical alternative measure for reducing pain associated with electrical excision of the cervix during LEEP." | 5.17 | Lidocaine spray compared with submucosal injection for reducing pain during loop electrosurgical excision procedure: a randomized controlled trial. ( Charoenkwan, K; Vanichtantikul, A, 2013) |
| "Topical capsaicin 8% was developed for the treatment of peripheral neuropathic pain." | 5.17 | Comparison of cooling and EMLA to reduce the burning pain during capsaicin 8% patch application: a randomized, double-blind, placebo-controlled study. ( Knolle, E; Kovacs, GG; Medwed, S; Scharbert, G; Schemper, M; Zadrazil, M, 2013) |
| "To determine the effectiveness of 6 mL of 2% lidocaine cervical gel for pain during intrauterine device (IUD) insertion." | 5.17 | Higher dose cervical 2% lidocaine gel for IUD insertion: a randomized controlled trial. ( Allen, RH; Goyal, V; Raker, C, 2013) |
| "Pertubation with lidocaine has been shown to reduce pain (on a VAS-scale) in women with endometriosis." | 5.17 | Quality of life in patients with endometriosis and the effect of pertubation with lidocaine - a randomized controlled trial. ( Bruse, C; Edelstam, G; Sjösten, A; Spira, J; Wickström, K, 2013) |
| "To compare the clinical efficacy between locally applied diclofenac diethylamine gel, EMLA cream and systemically given diclofenac sodium for the pain relief during extracorporeal shock wave lithotripsy (SWL) using Dornier Delta Compact Lithotripter." | 5.17 | Comparative study between three analgesic agents for the pain management during extracorporeal shock wave lithotripsy. ( Liu, J; Zang, YJ, 2013) |
| " The purpose of this prospective, randomized, double-blind study was to compare the pain of infiltration and pain of an incision and drainage procedure by using a buffered versus a nonbuffered 2% lidocaine with 1:100,000 epinephrine solution in symptomatic patients with a diagnosis of pulpal necrosis and associated acute swelling." | 5.17 | Buffered lidocaine for incision and drainage: a prospective, randomized double-blind study. ( Balasco, M; Beck, M; Drum, M; Nusstein, J; Reader, A, 2013) |
| "The goal of this study was to evaluate the effect of different methods of tourniquet application and lidocaine administration on MP injection pain." | 5.17 | Reducing the pain of microemulsion propofol injections: a double-blind, randomized study of three methods of tourniquet and lidocaine. ( Kim, HZ; Kim, K; Kim, NS; Kong, MH; Lee, DK; Lee, IO; Lim, BG; Sung Kim, Y, 2013) |
| "Lidocaine-prilocaine cream was most effective on probe-related pain, whereas lidocaine-ketorolac gel was most effective on sampling-related pain." | 5.17 | Noninfiltrative anesthesia for transrectal prostate biopsy: a randomized prospective study comparing lidocaine-prilocaine cream and lidocaine-ketorolac gel. ( Bufo, P; Carrieri, G; Cormio, L; Lorusso, F; Pagliarulo, V; Perrone, A; Sanguedolce, F; Selvaggio, O, 2013) |
| "The aim of the study was to assess the differences in reported pain from venipuncture comparing liposomal 4% lidocaine with placebo cream in a pediatric population." | 5.17 | A randomized, controlled trial to evaluate topical anesthetic for 15 minutes before venipuncture in pediatrics. ( Bokovoy, J; Boucher, J; Brenner, SM; Dusza, SW; Rupp, V; Weaver, K, 2013) |
| "High efficacy of intrathecal methylprednisolone acetate (MPA) with lidocaine has been reported in a large patient group suffering from intractable postherpetic neuralgia (PHN)." | 5.17 | No beneficial effect of intrathecal methylprednisolone acetate in postherpetic neuralgia patients. ( Kalkman, CJ; Kavelaars, A; Meulenhoff, PC; Rijsdijk, M; van der Tweel, I; van Wijck, AJ, 2013) |
| "Further studies are required to demonstrate whether tramadol or neostigmine have a role in the management of post operative pain when coadministered with lidocaine." | 5.17 | Efficacy of epidural lidocaine combined with tramadol or neostigmine on perineal analgesia in the horse. ( DeRossi, R; Maciel, FB; Módolo, TJ; Pagliosa, RC, 2013) |
| "The lidocaine-ketamine combination is most effective for decreasing the pain on propofol injection." | 5.17 | A prospective, randomized, double-blind study to compare the efficacy of lidocaine + metoclopramide and lidocaine + ketamine combinations in preventing pain on propofol injection. ( Chaudhary, K; Gogia, AR; Gupta, P, 2013) |
| "This study was designed to evaluate the role of epidural methadone-lidocaine in cancer pain combined or not to epidural dexamethasone." | 5.17 | Epidural methadone results in dose-dependent analgesia in cancer pain, further enhanced by epidural dexamethasone. ( Lauretti, GR; Mattos, AL; Rizzo, CC; Rodrigues, SW, 2013) |
| " Bedside VAC removal can be a source of great pain for patients, which we hypothesize can be decreased by topical lidocaine application." | 5.17 | Lidocaine analgesia for removal of wound vacuum-assisted closure dressings: a randomized double-blinded placebo-controlled trial. ( Christensen, TJ; Kubiak, EN; Thorum, T, 2013) |
| "Post-operative pain scores and incision site reactions were compared in healthy dogs undergoing routine castration at a county animal shelter and assigned to two treatment groups, namely: (1) lidocaine/bupivacaine (1mg/kg lidocaine+1mg/kg bupivacaine mixture; n=17), or (2) placebo (0." | 5.17 | Comparison of the effect of intratesticular lidocaine/bupivacaine vs. saline placebo on pain scores and incision site reactions in dogs undergoing routine castration. ( Jones, CA; Lascelles, BD; Posner, LP; Stevens, BJ, 2013) |
| "Topical capsaicin and eutectic mixture of local anesthetics (EMLA) have been found to be equally effective in minimizing the pain of venipuncture." | 5.17 | A comparative evaluation of local application of the combination of eutectic mixture of local anesthetics and capsaicin for attenuation of venipuncture pain. ( Agarwal, A; Gupta, D; Kishore, K; Rastogi, S; Singh, PK; Singh, U, 2013) |
| "This study tested the hypothesis that minimally invasive microneedles cause less pain during injection of lidocaine, but induce local anesthesia in humans with the same rapid onset and efficacy as intradermal lidocaine injection using hypodermic needles." | 5.16 | Rapid local anesthesia in humans using minimally invasive microneedles. ( Denson, DD; Felner, EI; Gupta, J; Prausnitz, MR, 2012) |
| "Lidocaine showed significantly reduced pain compared to placebo at all assessment points." | 5.16 | Local anesthetic effects of Lidocaine cream: randomized controlled trial using a standardized prick pain. ( Augustin, M; Herberger, K; Krause, K; Maier, K; Radtke, M; Zschocke, I, 2012) |
| "Topical lidocaine (5%) leads to sufficient pain relief in only 29%-80% of treated patients, presumably by small-fiber block." | 5.16 | Lidocaine patch (5%) produces a selective, but incomplete block of Aδ and C fibers. ( Krumova, EK; Maier, C; Westermann, A; Zeller, M, 2012) |
| "What's known on the subject? and What does the study add? Study Type - Harm Reduction RCT Level of Evidence 1b The combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block effectively counteracts probe and sampling related pain during transrectal prostate biopsy, but not pain due to periprostatic infiltration." | 5.16 | Combined perianal-intrarectal (PI) lidocaine-prilocaine (LP) cream and lidocaine-ketorolac gel provide better pain relief than combined PI LP cream and periprostatic nerve block during transrectal prostate biopsy. ( Bufo, P; Carrieri, G; Cormio, L; Lorusso, F; Pagliarulo, V; Perrone, A; Sanguedolce, F; Selvaggio, O, 2012) |
| "The aim of this study was to compare pain levels from arterial blood gas (ABG) sampling performed with or without application of lidocaine via jet injector." | 5.16 | Less painful arterial blood gas sampling using jet injection of 2% lidocaine: a randomized controlled clinical trial. ( Eslami, V; Farahmand, S; Hajiseyedjavady, H; Saeedi, M; Shahsavarinia, K, 2012) |
| "It has been reported in an open-label study that the combination of alkalinized lidocaine and heparin can immediately relieve the symptoms of urinary urgency, frequency, and pain associated with interstitial cystitis (IC)." | 5.16 | Alkalinized lidocaine and heparin provide immediate relief of pain and urgency in patients with interstitial cystitis. ( Davis, E; Franklin, A; Garner, WJ; Giesing, D; Kahn, BS; Koziol, J; Lakin, CM; Parsons, CL; Proctor, J; Zupkas, P, 2012) |
| " This study aimed to measure the incidence of propofol injection pain and evaluate the effect of lidocaine on pain caused during sedative upper GI endoscopic examinations." | 5.16 | Incidence of propofol injection pain and effect of lidocaine pretreatment during upper gastrointestinal endoscopy. ( Cho, KB; Chung, WJ; Hwang, JS; Jang, BK; Kim, ES; Kim, TY; Kwon, JS; Lee, JE; Park, KS; Park, WY, 2012) |
| "1% gentamicin cream is not an effective alternative to reduce significant bacteriuria and prevent urinary infection in patients who undergo clean intermittent catheterization." | 5.16 | [Clean vesical intermittent catheterization: lubrication of vesical catheter through lidocaine or gentamicine?]. ( Liotta, RF; Tarantino, ML, 2012) |
| "Intracervical 2% lidocaine gel does not decrease IUD insertion pain." | 5.16 | Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial. ( Davis, A; Maguire, K; Rosario Tejeda, L; Westhoff, C, 2012) |
| "The aim of this randomized, double-blind, placebo-controlled study was to evaluate the effect of ephedrine pretreatment on the intensity of rocuronium injection pain when rocuronium was applied by timing principle and also to compare this effect with lidocaine and placebo." | 5.16 | Can ephedrine pretreatment be effective in alleviating rocuronium injection pain? ( Akcaboy, EY; Akcaboy, ZN; Gogus, N; Soyal, OB; Turhan, G, 2012) |
| "Although pretreatment with a 5% lidocaine patch was found to be a safe, effective, and simple method of preventing venipuncture pain in children, this method did not reduce drug injection pain during the induction of anesthesia." | 5.16 | Availability of a 5% lidocaine patch used prophylactically for venipuncture- or injection-related pain in children. ( Byeon, GJ; Kim, CH; Lee, HJ; Shin, SW; Yoon, JU; Yoon, JY, 2012) |
| "A significantly higher proportion of patients in the placebo group (83 %) experienced pain compared to the lidocaine and combination groups (43 and 7 %, respectively; both, P < 0." | 5.16 | Reduction of pain on injection of propofol: combination of nitroglycerin and lidocaine. ( Jeon, Y, 2012) |
| "A trial was conducted, from January 2006 to April 2009, where 140 breast cancer patients were randomly assigned to standard topical lidocaine-4% cream and 99mTc-sulfur colloid injection, or to one of three other groups: placebo cream and 99mTc-sulfur colloid injection containing NaHCO3, 1% lidocaine, or NaHCO3 + 1% lidocaine." | 5.16 | Pain ratings by patients and their providers of radionucleotide injection for breast cancer lymphatic mapping. ( Baines, L; Buckenmaier, CC; Howard, RS; Radowsky, JS; Shriver, CD; Stojadinovic, A, 2012) |
| "To compare same-day and next-day pain control and safety of two anesthetic techniques utilizing 4% liquid lidocaine applied with sterile cotton swabs versus 3." | 5.16 | Randomized clinical trial of two anesthetic techniques for intravitreal injections: 4% liquid lidocaine on cotton swabs versus 3.5% lidocaine gel. ( Feuer, WJ; Goldhardt, R; Gregori, NZ; Hernandez, V; Kelley, L; Mattis, CA; Schiffman, JC; Shi, W; Vega, E; Weiss, MJ, 2012) |
| "To test the hypothesis that using Listerine mouthwash prior to administration of topical nasal lidocaine will result in improved pain and comfort outcomes during flexible nasolaryngoscopy (FNL)." | 5.16 | Pain and discomfort during flexible nasolaryngoscopy: a randomized, controlled trial assessing the efficacy of oral mouthwash and topical lidocaine. ( Bonaparte, JP; Corsten, M; Kilty, S; Odell, M, 2012) |
| " access, and blood sampling pain and stress affect hormone values, treatment with N(2)O or midazolam influence the glucose and stress hormone levels differently." | 5.16 | Effects of midazolam and nitrous oxide on endocrine and metabolic measurements in children. ( Ekbom, K; Jakobsson, J; Kalman, S; Marcus, C, 2012) |
| "Intravenous perioperative lidocaine decreases the incidence and severity of PPSP after breast cancer surgery." | 5.16 | Perioperative intravenous lidocaine decreases the incidence of persistent pain after breast surgery. ( Grigoras, A; Lee, P; Sattar, F; Shorten, G, 2012) |
| " Subcutaneous injection of lidocaine before LP for local anesthesia is not a pain-free procedure." | 5.16 | Needle-free jet injection of lidocaine for local anesthesia during lumbar puncture: a randomized controlled trial. ( Bryson, M; Bulloch, B; Ferayorni, A; Yniguez, R, 2012) |
| "To compare the efficacy of pretreatment with parecoxib and lidocaine to prevent rocuronium injection pain." | 5.16 | Prevention of pain on injection of rocuronium: a comparison of lidocaine with different doses of parecoxib. ( Liu, J; Xiang, Y; Zhang, Y, 2012) |
| "VAS pain scores during arterial puncture were comparable in both groups and Rapydan was non-inferior to subcutaneous lidocaine." | 5.16 | Lidocaine/tetracaine patch (Rapydan) for topical anaesthesia before arterial access: a double-blind, randomized trial. ( Dunkler, D; Golescu, A; Grubhofer, G; Hoeferl, M; Hutschala, D; Jaeger, W; Mayer, L; Ruetzler, K; Sessler, DI; Sima, B; You, J, 2012) |
| "To compare the effect of 1% lidocaine-epinephrine [1:100,000] buffered with sodium bicarbonate with skin cooling for 2 minutes with ice in reducing the pain of infiltration of anesthetic solution." | 5.16 | Prospective comparison between buffered 1% lidocaine-epinephrine and skin cooling in reducing the pain of local anesthetic infiltration. ( Al Shahwan, MA, 2012) |
| "Epidural lignocaine injection produced longer duration of antinociception with lower frequency of pain-associated behavioural changes; while treatment with epidural tramadol injection allowed the goats to continue grazing once the rubber ring has been applied." | 5.16 | Effect of epidural tramadol and lignocaine on physiological and behavioural changes in goats subjected to castration with a high tension band. ( Ajadi, RA; Gazal, OS; Martins, MM; Owanikin, AO, 2012) |
| "kg(-1) and lidocaine 20 mg mixture significantly reduced propofol pain when compared with control group." | 5.16 | Prevention of propofol injection pain in children: a comparison of pretreatment with tramadol and propofol-lidocaine mixture. ( Borazan, H; Et, T; Kececioglu, A; Otelcioglu, S; Sahin, O; Uluer, MS, 2012) |
| " Pain scores among lidocaine and placebo arms were similar at tenaculum placement (lidocaine and placebo: median, 4; range, 0-10; P = ." | 5.16 | Cervical lidocaine for IUD insertional pain: a randomized controlled trial. ( Allsworth, JE; Madden, T; McNicholas, CP; Peipert, JF; Secura, G; Zhao, Q, 2012) |
| "To compare the level of pain and discomfort associated with subcutaneous infiltration of lidocaine diluted with normal saline to that associated with traditionally buffered lidocaine." | 5.16 | Virtually painless local anesthesia: diluted lidocaine proves to be superior to buffered lidocaine for subcutaneous infiltration. ( Aguilera, SB; Caperton, C; Chimento, S; Zaiac, M; Zaulyanov-Scanlan, L, 2012) |
| " Pain was approximately 2/10 with the use of 5% lidocaine numbing cream applied approximately 45 minutes before each procedure." | 5.16 | Treatment of benign pigmented lesions using a long-pulse alexandrite laser. ( Blalock, T; Houghton, N; Ross, EV; Winstanley, D, 2012) |
| "02 mg, % 2 lidocaine 40 mg, metoclopramide 10 mg, and ketamine 100 microg/kg yields propofol induced pain 38%, 76%, 76%, and 58% respectively." | 5.16 | The effects of remifentanil, lidocaine, metoclopramide, or ketamine pretreatment on propofol injection pain. ( Aktay, M; Ozlü, O; Polat, R, 2012) |
| "The aim of the study was to evaluate the efficacy of topical 2% lidocaine gel in reducing pain and discomfort associated with nasogastric tube insertion (NGTI) and compare lidocaine to ordinary lubricant gel in the ease in carrying out the procedure." | 5.15 | Lidocaine gel as an anesthetic protocol for nasogastric tube insertion in the ED. ( Behrbalk, E; Haim, A; Halpern, P; Uri, O; Yosefov, L, 2011) |
| "This study evaluated the effects of topical lidocaine on skin sensation and on intradermal capsaicin-induced pain and hyperalgesia." | 5.15 | Effects of lidocaine patch on intradermal capsaicin-induced pain: a double-blind, controlled trial. ( Lam, VY; Schulteis, G; Wallace, M, 2011) |
| "The objective of the study was to compare the efficacy of dimethyl sulfoxide (DMSO) mixed with lignocaine and eutectic mixture of local anesthetics (EMLA) cream as topically applied surface anesthetics in relieving pain during shock wave lithotripsy (SWL) in a prospective randomized study." | 5.15 | Dimethyl sulfoxide with lignocaine versus eutectic mixture of local anesthetics: prospective randomized study to compare the efficacy of cutaneous anesthesia in shock wave lithotripsy. ( Ganesamoni, R; Kumar, S; Mandal, AK; Prasad, S; Singh, SK, 2011) |
| "To determine the analgesic effect of supplemental intracameral lidocaine 1% during phacoemulsification under topical anaesthesia, and to assess the risk factors associated with pain." | 5.15 | Analgesic effect of supplemental intracameral lidocaine during phacoemulsification under topical anaesthesia: a randomised controlled trial. ( Au Eong, KG; Fam, HB; Heng, WJ; Lee, HM; Saw, SM; Tan, CS, 2011) |
| "The combination of fentanyl and lidocaine before pin fixation is useful in preventing severe hemodynamic response to pain stimuli, such as pin fixation, and in increasing total antioxidant levels in the post-fixational period during craniotomy in adults." | 5.15 | Efficacy of fentanyl and/or lidocaine on total antioxidants and total oxidants during craniotomy. ( Alptekin, M; Erkutlu, I; Geyik, M; Gok, A; Mizrak, A; Oner, U; Sen, E, 2011) |
| "In a randomized, double-blind, parallel-design, quasiexperimental study, we compared pain ratings of adult patients receiving either intradermal buffered lidocaine or intradermal bacteriostatic normal saline before IV catheterization." | 5.15 | Local anesthesia before IV catheterization. ( Burke, SD; Bye, RO; Desmond, PC; Rees, YW; Vercler, SJ, 2011) |
| "To determine technical and clinical factors associated with pain when using an analgesic protocol with 50% nitrous oxide/oxygen and anesthetic cream (lidocaine and prilocaine, Emla(®)) for children with cerebral palsy undergoing botulinum toxin injections." | 5.15 | Determining the technical and clinical factors associated with pain for children undergoing botulinum toxin injections under nitrous oxide and anesthetic cream. ( Blajan, V; Brochard, S; Garlantezec, R; Houx, L; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2011) |
| "The lidocaine/flurbiprofen axetil combination, compared with lidocaine 40 mg or flurbiprofen 50 mg, effectively reduces pain during the injection of propofol." | 5.15 | Efficacy of the lidocaine/flurbiprofen axetil combination for reducing pain during the injection of propofol. ( Fujii, Y; Itakura, M, 2011) |
| " We intended to evaluate whether the addition of 10% lidocaine spray to a paracervical block decreases pain during cervical dilation and uterine aspiration." | 5.15 | Lidocaine spray in addition to paracervical block reduces pain during first-trimester surgical abortion: a placebo-controlled clinical trial. ( Alanbay, I; Başer, I; Ercan, CM; Karasahin, KE; Mesten, Z; Simsek, C, 2011) |
| "To determine the relative effectiveness of liposomal lidocaine, sucrose, and their combination for reducing pain in term newborns." | 5.15 | Effect of liposomal lidocaine and sucrose alone and in combination for venipuncture pain in newborns. ( Hogan, ME; Katz, J; Kikuta, A; Koren, G; Parvez, E; Shah, V; Stephens, D; Taddio, A, 2011) |
| " Local forearm/wrist pain is relatively frequent in this setting, and is not significantly prevented by intra-arterial lidocaine." | 5.15 | Intra-arterial lidocaine versus saline to reduce peri-procedural discomfort in patients undergoing percutaneous trans-radial or trans-ulnar coronary procedures. ( Agostoni, P; Biondi-Zoccai, GG; Moretti, C; Omedè, P; Romagnoli, E; Sangiorgi, G; Sciuto, F; Sheiban, I, 2011) |
| " High dose intravenous opioids form the mainstay of procedural burns pain management; however it was suggested that intravenous lidocaine assists with minimising the pain experience." | 5.15 | Adjuvant use of intravenous lidocaine for procedural burn pain relief: a randomized double-blind, placebo-controlled, cross-over trial. ( Cleland, H; Costello, V; Ferraro, F; Konstantatos, A; Paul, E; Spinks, A; Wasiak, J, 2011) |
| "The aim of the present randomized clinical study was to assess the efficacy of simplex lidocaine in local anesthesia for inguinal hernia mesh-repairs, compare analgesia of three different concentrations of lidocaine, and explore use of lower concentrations of lidocaine in local anesthesia for inguinal hernia mesh-repairs." | 5.15 | Comparison of three concentrations of simplex lidocaine in local anesthesia for inguinal hernia mesh-repairs. ( Ban, LJ; Gong, YP; Lei, WZ; Liu, Y; Yang, L; Zeng, Y; Zhang, W, 2011) |
| "Pain frequency was 90% in the saline group, whereas the frequencies were significantly lower in the lidocaine and methylene blue groups (26." | 5.15 | Pain on injection of propofol: a comparison of methylene blue and lidocaine. ( Akinci, SB; Aypar, Ü; Salman, AE; Salman, MA; Saricaoglu, F, 2011) |
| "Pretreatment with combination of small-dose ephedrine and lidocaine could reduce the incidence and intensity of propofol-induced pain and also result in more stable hemodynamic profile, but however, the combination of two drugs failed to work better in further reduction of pain." | 5.15 | The effect of combined ephedrine and lidocaine pretreatment on pain and hemodynamic changes due to propofol injection. ( Kayalha, H; Khezri, MB, 2011) |
| "The addition of 3% sevoflurane at the time of preoxygenation for 1 min along with routine use of lidocaine-tourniquet completely prevented pain upon propofol injection, whereas sevoflurane by itself provided similar analgesia to premixed lidocaine with propofol." | 5.15 | Sevoflurane to alleviate pain on propofol injection. ( Ali, MS; DeSousa, K, 2011) |
| "To test the hypothesis that using lidocaine nasal spray will result in improved pain and comfort outcomes during an extended flexible endoscopic nasal examination." | 5.15 | A double-blind randomised controlled trial assessing the efficacy of topical lidocaine in extended flexible endoscopic nasal examinations. ( Bonaparte, JP; Javidnia, H; Kilty, S, 2011) |
| " The purpose of this study was to evaluate efficacy of lidocaine/prilocaine cream in decreasing the pain of injection for sentinel lymph node biopsy." | 5.15 | Do topical anesthetics reduce periareolar injectional pain before sentinel lymph node biopsy? ( Cusick, TE; Helmer, SD; O'Connor, JM; Osland, JS; Tenofsky, PL, 2011) |
| "Rapid injection was less painful than after pretreatment with lidocaine 0." | 5.15 | Rapid injection of propofol reduces vascular pain and facilitates Laryngeal Mask Airway insertion. ( Inomata, S; Shimizu, T; Tanaka, M, 2011) |
| " This study aimed to determine whether the success rate and pain of intravenous cannulation is affected by prior injection of intradermal lidocaine." | 5.15 | Effect of intradermal anaesthesia on success rate and pain of intravenous cannulation: a randomized non-blind crossover study. ( Checketts, MR; Hendry, F; McLeod, GA, 2011) |
| "This trial will define the role of 2% lidocaine in the treatment of painful infectious mouth conditions." | 5.15 | A double blind, randomised placebo controlled trial of topical 2% viscous lidocaine in improving oral intake in children with painful infectious mouth conditions. ( Babl, FE; Hopper, SM; Lee, KJ; McCarthy, M; Oakley, E; Tancharoen, C, 2011) |
| "To determine if the intravenous co-administration of equal volumes of lidocaine and nalbuphine, with undiluted normal saline, prevents injection pain caused by nalbuphine." | 5.15 | Equal volumes of undiluted nalbuphine and lidocaine and normal diluted saline prevents nalbuphine-induced injection pain. ( Chau, SW; Chen, MK; Cheng, KI; Feng, YT; Ku, CL; Shen, YC; Wang, FY, 2011) |
| "5% bupivacaine, in a double-blinded manner for pain on intradermal injection and pain during subsequent intravenous (IV) cannulation with an 18-gauge catheter." | 5.15 | A comparison of the pain perceived during intravenous catheter insertion after injection with various local anesthetics. ( Barber, MK; Beck, RM; Engoren, M; Thomas, R; Zbierajewski, FJ, 2011) |
| "The aim of this study was to compare the efficacy of topical piroxicam and EMLA cream on pain control and subsequent inflammation in neodymium:yttrium-aluminum-garnet (Nd:YAG) 1,064 nm laser hair removal in female volunteers." | 5.14 | A clinical comparison of topical piroxicam and EMLA cream for pain relief and inflammation in laser hair removal. ( Akinturk, S; Eroglu, A, 2009) |
| "Breast-feeding in infants under age 6 months and use of sucrose or lidocaine-prilocaine in children age 6 to 48 months significantly reduced crying time and pain scores compared with controls." | 5.14 | Interventions to reduce pain during vaccination in infancy. ( Dallar, Y; Dilli, D; Küçük, IG, 2009) |
| "To determine the effectiveness of lidocaine 2% gel vstetracaine 1% drops in primary pterygium surgery." | 5.14 | Randomised controlled trial on the effectiveness of lidocaine gel vs tetracaine drops as the sole topical anaesthetic agent for primary pterygium surgery. ( Cheng, LL; Lam, DS; Lam, PT; Lau, TT; Leung, GY; Young, AL, 2009) |
| "Our findings suggest that the combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block provides better pain control than the 2 modalities alone during the sampling part of transrectal ultrasound guided prostate biopsy with no increase in the complication rate." | 5.14 | Combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block for pain control during transrectal ultrasound guided prostate biopsy: a randomized, controlled trial. ( Autorino, R; Barbone, F; De Maria, M; Di Lorenzo, G; Giannarini, G; Manassero, F; Mogorovich, A; Morelli, G; Selli, C; Valent, F, 2009) |
| "To determine whether a difference exists in perceived pain during preprocedure anesthetic injection for bone marrow biopsy between buffered and unbuffered lidocaine, to determine whether pain levels change over time, and to investigate relationships between perceived pain scores and other variables." | 5.14 | Use of buffered lidocaine in bone marrow biopsies: a randomized, controlled trial. ( Curran, CR; Lamb, T; Ruegg, TA, 2009) |
| "75% was more effective than lidocaine 2% in preventing pain and improving patient and surgeon comfort during cataract surgery, with similar toxicity." | 5.14 | Comparative study of topical anaesthesia with lidocaine 2% vs levobupivacaine 0.75% in cataract surgery. ( Dios, E; Diz, JC; Fernández, SA, 2009) |
| "To compare injection pain of a HA gel with preincorporated lidocaine with that with a non-lidocaine formulation." | 5.14 | Comparison of injection comfort of a new category of cohesive hyaluronic acid filler with preincorporated lidocaine and a hyaluronic acid filler alone. ( De Boulle, K; Levy, PM; Raspaldo, H, 2009) |
| "A topical lidocaine patch is effective in the treatment of posttraumatic peripheral neuropathy (PTPN), but it is not suited for breakthrough pain because of difficulty with an additional application." | 5.14 | The analgesic effect of a metered-dose 8% lidocaine pump spray in posttraumatic peripheral neuropathy: a pilot study. ( Kanai, A; Koto, M; Okamoto, H; Okamoto, T; Segawa, Y, 2009) |
| "To determine whether adding ephedrine to propofol is as effective as adding lidocaine at reducing injection pain, and its effects on hemodynamics." | 5.14 | Admixture of ephedrine to offset side effects of propofol: a randomized, controlled trial. ( Austin, JD; Parke, TJ, 2009) |
| "Sodium amobarbital decreased spontaneous pain by 73% (vs 46% with lidocaine) and normalized sensory abnormalities at or above the level of injury in 3 patients (as compared to just 1 patient with lidocaine), 2 of whom had transitional zone allodynia/hyperalgesia." | 5.14 | Effects of intravenous sodium amobarbital vs lidocaine on pain and sensory abnormalities in patients with spinal cord injury. ( Bharatwal, B; Krassioukov, AV; Mailis-Gagnon, A; Yegneswaran, B, 2009) |
| "A common drawback of propofol is pain on injection and lignocaine is commonly mixed with propofol to reduce the incidence and severity of this pain." | 5.14 | Prevention of propofol pain: a comparative study. ( Jayaraman, L; Sethi, M; Sethi, N; Sharma, S; Sood, J, 2009) |
| "A metered-dose 8% lidocaine pump spray produced prompt analgesia in patients with PBFD-related pain without severe side effects." | 5.14 | 8% Lidocaine pump spray relieves pain associated with peripheral blood flow disorders. ( Kanai, A; Suzuki, A, 2009) |
| "The aim of this study was to evaluate whether the use of lidocaine 10% spray was effective in pain control during hysterosalpingography (HSG)." | 5.14 | Lidocaine 10% spray reduces pain during hysterosalpingography: a randomized controlled trial. ( Alanbay, I; Baser, I; Gezginc, K; Karasahin, E; Keskin, U, 2009) |
| "For women undergoing first-trimester suction curettage with conscious sedation, there was no clinically meaningful difference in pain relief between paracervical and intracervical lidocaine." | 5.14 | Paracervical compared with intracervical lidocaine for suction curettage: a randomized controlled trial. ( Kingston, J; Lukacz, ES; Mankowski, JL; Moran, T; Nager, CW, 2009) |
| "This study compared the efficacy in terms of pain of injection, time of onset and duration of action of digital blocks of bupivacaine 0." | 5.14 | Comparison of bupivacaine and lidocaine with epinephrine for digital nerve blocks. ( Al-Hamid, S; Al-Mulhim, M; Al-Salamah, M; Alhelail, M, 2009) |
| "The objectives were to determine whether pretreatment with needleless jet-delivered lidocaine decreases self-reported pain in children undergoing needle insertion in the emergency department (ED) and to explore whether pretreatment with a jet device decreases self-reported pain in children undergoing needle insertion in the ED." | 5.14 | A randomized, double-blind controlled study of jet lidocaine compared to jet placebo for pain relief in children undergoing needle insertion in the emergency department. ( Auerbach, M; Mojica, M; Tunik, M, 2009) |
| "Perianal anesthesia with lidocaine-prilocaine cream may solely be sufficient to decrease the pain during prostate biopsy." | 5.14 | Is only perianal anesthesia with lidocaine-prilocaine cream sufficient to decrease the pain during transrectal ultrasound-guided prostate biopsy? A prospective randomized study. ( Kandirali, E; Metin, A; Semercioz, A; Serin, E; Ulukaradag, E; Uysal, B, 2009) |
| "In this prospective and randomized study, we aimed to compare the efficacy of a eutectic mixture of local anesthetics (EMLA) cream, diclofenac sodium (DS) and EMLA in combination with DS (EMLA+DS) for pain management during extracorporeal shock wave lithotripsy (ESWL)." | 5.14 | Comparison of three analgesic treatment protocols for pain management during extracorporeal shock wave lithotripsy. ( Eryildirim, B; Faydaci, G; Kuyumcuoğlu, U; Tarhan, F; Uruç, F, 2009) |
| "Infiltration anaesthesia with articaine, a local anaesthetic able to penetrate bone, may relieve procedural pain better than lidocaine in bone marrow aspiration and biopsy." | 5.14 | Comparison of articaine and lidocaine for infiltration anaesthesia in patients undergoing bone marrow aspiration and biopsy. ( Elonen, E; Kuivalainen, AM; Niemi-Murola, L; Rosenberg, PH; Widenius, T, 2010) |
| "In patients with PHN and painful DPN failing to respond to monotherapy, combination therapy with 5% lidocaine medicated plaster and pregabalin provides additional clinically relevant pain relief and is safe and well-tolerated." | 5.14 | Efficacy and safety of combination therapy with 5% lidocaine medicated plaster and pregabalin in post-herpetic neuralgia and diabetic polyneuropathy. ( Baron, R; Binder, A; Leijon, G; Mayoral, V; Serpell, M; Steigerwald, I, 2009) |
| "To compare efficacy and safety of 5% lidocaine medicated plaster with pregabalin in patients with post-herpetic neuralgia (PHN) or painful diabetic polyneuropathy (DPN)." | 5.14 | 5% lidocaine medicated plaster versus pregabalin in post-herpetic neuralgia and diabetic polyneuropathy: an open-label, non-inferiority two-stage RCT study. ( Baron, R; Binder, A; Leijon, G; Mayoral, V; Serpell, M; Steigerwald, I, 2009) |
| "Lidocaine injections increased local pain thresholds and decreased remote secondary heat hyperalgesia in FM patients, emphasizing the important role of peripheral impulse input in maintaining central sensitization in this chronic pain syndrome; similar to other persistent pain conditions such as irritable bowel syndrome and complex regional pain syndrome." | 5.14 | Enhanced central pain processing of fibromyalgia patients is maintained by muscle afferent input: a randomized, double-blind, placebo-controlled study. ( Nagel, S; Price, DD; Robinson, ME; Staud, R, 2009) |
| "Our study demonstrated that the combination treatment of two different analgesic modalities, alfentanil and lidocaine, could prevent the moderate and severe pain on propofol injection, and reduce the incidence of mild pain compared with each drug alone." | 5.14 | Prevention of propofol-induced pain in children: combination of alfentanil and lidocaine vs alfentanil or lidocaine alone. ( Kim, JS; Kim, JY; Kwak, HJ; Min, SK, 2009) |
| "The purpose of this study was to compare the effectiveness of topically applied lidocaine-prilocaine (EMLA) cream with local anesthetic infiltration in the reduction of pain during perineal suturing after childbirth." | 5.14 | Comparison between lidocaine-prilocaine cream (EMLA) and mepivacaine infiltration for pain relief during perineal repair after childbirth: a randomized trial. ( Cromi, A; Franchi, M; Gaudino, F; Ghezzi, F; Scarperi, S; Siesto, G, 2009) |
| "The NTG adding to lidocaine in intravenous regional anesthesia shortens onset times of sensory and motor block and decreases the tourniquet and postoperative pain, without any side effect." | 5.14 | The effect of nitroglycerin as an adjuvant to lidocaine in intravenous regional anesthesia. ( Abbasivash, R; Aghdashi, MM; Hassani, E; Shirvani, M, 2009) |
| "We conducted a prospective randomized study to assess the effects of preceding lidocaine on the incidence and intensity of propofol-induced pain." | 5.14 | [Effects of the injection method of lidocaine on preventing injection pain during anesthesia induction by target controlled infusion with propofol]. ( Kajiyama, S; Okada, Y; Osawa, Y, 2009) |
| "To investigate the alleviation effect of vein pretreatment and granisetron/lidocaine combination on propofol injection-induced pain." | 5.14 | [Effects of granisetron/lidocaine combination on propofol injection-induced pain: a double-blind randomized clinical trial]. ( Lin, XM; Ma, YS; Zhou, J, 2009) |
| "It is a common practice for medical practitioners to use subcutaneous infiltration of lidocaine to alleviate the pain of intravenous cannulation or line insertion." | 5.14 | The effect of needle bevel position on pain for subcutaneous lidocaine injection. ( Arheart, KL; Birnbach, DJ; Candiotti, K; Curia, L; Koyyalamudi, P; Rodriguez, Y, 2009) |
| "Between Jan 13, 2006, and April 30, 2009, 140 patients with early breast cancer were randomly assigned in a 1:1:1:1 fashion to receive the standard topical 4% lidocaine cream and injection of [(99m)Tc]Tc-sulfur colloid (n=35), or to one of three other study groups: topical placebo cream and injection of Tc-sulfur colloid containing either sodium bicarbonate (n=35), 1% lidocaine (n=35), or sodium bicarbonate and 1% lidocaine (n=35)." | 5.14 | Standard versus pH-adjusted and lidocaine supplemented radiocolloid for patients undergoing sentinel-lymph-node mapping and biopsy for early breast cancer (PASSION-P trial): a double-blind, randomised controlled trial. ( Buckenmaier, CC; Henry, LR; Howard, RS; Jurgens, JS; Kwon, KH; Peoples, GE; Schuyler, B; Shriver, CD; Stojadinovic, A, 2009) |
| "Topical TetraVisc solution was superior to lidocaine 2% gel for pain control in patients undergoing clear corneal phacoemulsification." | 5.14 | Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery. ( Agarwal, S; Chalam, KV; Grover, S; Gupta, SK; Murthy, RK, 2009) |
| "5 mg kg(-1) for prevention of propofol induced pain." | 5.14 | Prevention of pain on injection of propofol: a comparison of lidocaine with different doses of paracetamol. ( Borazan, H; Erdem, TB; Kececioglu, M; Otelcioglu, S, 2010) |
| "To compare the pain perception between lidocaine and plain aqueous gel during assessment of postvoid residual volume and the Q-tip test." | 5.14 | Lidocaine jelly and plain aqueous gel for urethral straight catheterization and the Q-tip test: a randomized controlled trial. ( Ayaz, R; Harmanli, OH; Knee, A; Okafor, O, 2009) |
| "We consider the injection of intracapsular lidocaine a reproductible technique and effective for both improving tolerance and diminishing the pain related to transrectal ultrasound-guided prostate biopsy without increasing morbidity." | 5.14 | [Prospective randomized study on the use of lidocaine local anesthesia in prostate biopsy]. ( Alvarez Barrera, A; Fabuel Deltoro, M; Juan Escudero, J; Marques Vidal, E; Montoliu García, A; Ramos de Campos, M; Serrano de la Cruz Torrijos, F, 2009) |
| " Patients receiving lidocaine reported less pain than control patients during the dressing change (4." | 5.14 | The impact of topical lidocaine on pain level assessment during and after vacuum-assisted closure dressing changes: a double-blind, prospective, randomized study. ( Agarwal, JP; Drum, M; Franczyk, M; Gottlieb, LJ; Lohman, RF; Rupani, G, 2009) |
| "The dermal filler formulated with lidocaine is effective in reducing procedural pain during correction of facial wrinkles and folds while maintaining a similar safety and effectiveness profile to the filler without lidocaine." | 5.14 | A multi-center, double-blind, randomized controlled study of the safety and effectiveness of Juvéderm injectable gel with and without lidocaine. ( Bank, DE; Boyd, CM; Gold, MH; Murphy, DK; Thomas, JA; Weinkle, SH, 2009) |
| "The combination of intrarectal lidocaine gel and periprostatic longer-acting LA agents significantly reduces the pain related to prostate biopsy, whereas intrarectal lidocaine gel administration alone does not reduce pain." | 5.14 | Topical and long-acting local anesthetic for prostate biopsy: a prospective randomized placebo-controlled study. ( Kilic, O; Kilinc, M; Serarslan, A; Taspinar, B; Yurdakul, T, 2009) |
| "The objective of this study was to compare the efficiency oflidocaine with that of plain saline for paracervical pain relief during fractional curettage." | 5.14 | Comparison of lidocaine 1% and normal saline in paracervical anesthesia for decreasing of pain in curettage. ( Alavi, A; Aliabadi, E; Amirian, M; Rajai, M; Zare, S, 2009) |
| "To examine the efficacy and safety of a new topical anesthetic containing a disinfection ingredient (LidoDin cream) in reducing the pain associated with venipuncture by comparing it with the proven eutectic mixture of lidocaine 2." | 5.14 | Lidocaine-based topical anesthetic with disinfectant (LidoDin) versus EMLA for venipuncture: a randomized controlled trial. ( Hadash, A; Kassis, I; Knaani-Levinz, H; Shachor-Meyouhas, Y; Shavit, I, 2009) |
| "The aim of this study was to compare the efficacy of intravenous pretreatment with fentanyl 50 microg, fentanyl 100 microg, and lidocaine 40 mg, preceded by venous occlusion, for reducing pain on injection of propofol in adult Japanese surgical patients." | 5.14 | A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients. ( Fujii, Y; Itakura, M, 2009) |
| "To study the effects of a paracervical block with combined ketorolac and lidocaine on perceived pain during first-trimester surgical abortion." | 5.14 | Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial. ( Burke, A; Cansino, C; Edelman, A; Jamshidi, R, 2009) |
| " Each of the four propofol solutions was administered 88 times; of patients receiving Baxter propofol+saline, 74 (84%) had pain; when mixed with 2% lidocaine 45 (50." | 5.14 | Pain on injection from propofol may be avoided by changing its formulation. ( Alcover, J; Aldrete, JA; Johnson, SC; Montpetit, FH; Otero, P; Parietti, A; Quiroga, D; Torrieri, A, 2010) |
| " The lidocaine group showed significantly lower pain scores for tenaculum placement (mean+/-standard deviation: 0." | 5.14 | Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial. ( Chudnoff, S; Einstein, M; Levie, M, 2010) |
| "The lidocaine patch 5% does not significantly improve pain control in polytrauma patients with traumatic rib fractures." | 5.14 | Randomized, double-blind, placebo-controlled trial using lidocaine patch 5% in traumatic rib fractures. ( Bettendorf, M; Frye, I; Horton, ZA; Ingalls, NK; Rodriguez, C, 2010) |
| "Topical lidocaine (LDC) treatment using a gel or patch preparation is effective in the treatment of postherpetic neuralgia (PHN), but neither is suited for the eye in patients with ophthalmic PHN." | 5.14 | Lidocaine eye drops attenuate pain associated with ophthalmic postherpetic neuralgia. ( Kanai, A; Niki, Y; Okamoto, H; Okamoto, T; Suzuki, K, 2010) |
| "The aim of this study was to evaluate the efficacy of a combined topical and local anesthesia consisting of a transrectal lidocaine suppository followed by periprostatic nerve block (PNB) in comparison to the combination of transrectally applied lidocaine gel followed by PNB and PNB alone as methods of reducing pain during transrectal prostate biopsy." | 5.14 | Addition of lidocaine suppositories to periprostatic nerve block enhances pain control in prostate biopsies: a placebo-controlled randomized trial. ( Fink, KG; Paras, L; Szlauer, R, 2010) |
| "No statistically significant difference was found among the mean pain scores of women during the procedure in the dexketoprofen and saline, placebo and lidocaine, and dexketoprofen and lidocaine groups." | 5.14 | Comparison of oral nonsteroidal analgesic and intrauterine local anesthetic for pain relief in uterine fractional curettage: a randomized, double-blind, placebo-controlled trial. ( Api, M; Api, O; Emeksiz, MB; Ergen, B; Ugurel, V; Unal, O, 2010) |
| "Injection pain during propofol administration can be particularly distressing in children." | 5.14 | Does the newer preparation of propofol, an emulsion of medium/long chain triglycerides cause less injection pain in children when premixed with lignocaine? ( Krishna, HM; Nittala, A; Varghese, E, 2010) |
| "This study determined, in humans, the effects of (i) the number of within-session task repetitions (72 or 144 over a period of 15 or 30 min, respectively) on the time course of motor learning in a long-term (seven consecutive daily motor-training sessions and a 1-week post-follow-up) novel tongue-task training regime and (ii) somatosensory manipulations (capsaicin-induced intra-oral pain or lidocaine-induced sensory loss of the tongue tip) on motor learning in a short-term (single motor-training session consisting of 72 within-session task repetitions over a period of 15 min) novel tongue-task training regime." | 5.14 | The effects of training time, sensory loss and pain on human motor learning. ( Arendt-Nielsen, L; Boudreau, SA; Hennings, K; Sessle, BJ; Svensson, P, 2010) |
| " LABEL is a trial determining the efficacy of pain relief of an injection of lidocaine and bupivacaine at the site of painful osteoporotic vertebral compression fractures in unblinded patients." | 5.14 | Local Anesthesia with Bupivacaine and Lidocaine for Vertebral Fracture trial (LABEL): a report of outcomes and comparison with the Investigational Vertebroplasty Efficacy and Safety Trial (INVEST). ( Brinjikji, W; Comstock, BA; Gray, L; Kallmes, DF, 2010) |
| "To compare the effectiveness of a combination of intrauterine lignocaine and vaginal misoprostol in reducing pain at hysteroscopy and endometrial aspiration (EA)." | 5.14 | Efficacy of intrauterine lignocaine plus vaginal misoprostol for pain relief in premenopausal women undergoing endometrial aspiration and ambulatory hysteroscopy. ( Dadhwal, V; Gupta, B; Gupta, N; Mittal, S, 2010) |
| " lidocaine in reducing pain from i." | 5.14 | Vapocoolant spray vs subcutaneous lidocaine injection for reducing the pain of intravenous cannulation: a randomized, controlled, clinical trial. ( Page, DE; Taylor, DM, 2010) |
| "In a randomized double-blinded clinical trial, 150 patients (50 per group) with irreversible pulpitis were given placebo, 600 mg ibuprofen, or 75 mg indomethacin 1 hour before local anesthesia." | 5.14 | The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis. ( Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR, 2010) |
| "Pain score results showed that the use of intrarectal lidocaine spray provided significantly better pain control than cream and anaesthetic gel." | 5.14 | Lidocaine spray administration during transrectal ultrasound guided prostate biopsy modified the discomfort and pain of the procedure: results of a randomized clinical trial. ( Daniele, C; Dell'Atti, L, 2010) |
| "No differences in overall pain sensation between the substances were detected during and after liposuction except a more rapid onset with lidocaine (less pain after 15 min, p < 0." | 5.14 | Double-blind, randomized, intraindividual comparison study of the efficacy of prilocaine and lidocaine in tumescent local anesthesia. ( Augustin, M; Herberger, K; Maier, K; Sattler, G; Sommer, B, 2010) |
| "The addition of lidocaine substantially reduces the pain of LGP-HA injection without altering safety." | 5.14 | A lidocaine-containing formulation of large-gel particle hyaluronic acid alleviates pain. ( Bank, D; Brandt, F; Cross, SL; Weiss, R, 2010) |
| "To compare the efficacy of 2% lidocaine "timing" on alleviation of pain upon induction using propofol or etomidate." | 5.14 | Does lidocaine more effectively prevent pain upon induction with propofol or etomidate when given preemptively than when mixed with the drug? ( Brock, MF; Grace, BE; Groban, L; Hillegass, G; Houle, TT; Morley, B, 2010) |
| "To compare the efficacy and side effects profile of topical 2% lidocaine gel with injectable 2% lidocaine solution as local anaesthetics for incision and curettage of chalazion." | 5.14 | Comparison of topical lidocaine [2% gel] and injectable lidocaine [2% solution] for incision and curettage of chalazion in Ilorin, Nigeria. ( Bolaji, BO; Mahmoud, AO; Osayande, OO, 2010) |
| "To determine the effect of lidocaine gel on pain from TCu-380AIUD insertion." | 5.14 | Effect of lidocaine gel on pain from copper IUD insertion: a randomized double-blind controlled trial. ( Kazemi, F; Mohammad-Alizadeh-Charandabi, S; Seidi, S, 2010) |
| "Pain on injection limits the use of propofol in children." | 5.13 | Avoiding propofol injection pain in children: a prospective, randomized, double-blinded, placebo-controlled study. ( Boufroukh, D; Bringuier, S; Capdevila, X; Dadure, C; Hocquet, AF; Lubrano, JF; Raux, O; Rochette, A, 2008) |
| "The overall incidence of pain on injection was 31/133 (23%) in the propofol-MCT/LCT plus lidocaine group vs." | 5.13 | Does addition of lidocaine to medium- and long-chain triglyceride propofol emulsions significantly reduce pain on injection? ( Jamjamrat, G; Kosittanasan, S; Krobbuaban, B; Kumkeaw, S; Siriwan, D; Tanomsat, M; Thanetses, K, 2008) |
| "To compare the efficacy of oral naproxen with intrauterine instillation of 1% lignocaine for pain relief in women undergoing hysterosalpingography (HSG) as an infertility investigation." | 5.13 | Comparison of oral naproxen and intrauterine lignocaine instillation for pain relief during hysterosalpingography. ( Ghosh, B; Gupta, N; Mittal, S, 2008) |
| "To study the effect of the venous occlusion duration using lidocaine on the incidence and severity of propofol induced pain." | 5.13 | Duration of venous occlusion with lidocaine for preventing propofol induced pain. ( Abu-Ali, HM; Al-Ghanem, SA; Ammari, BA; Badran, IZ; Daradkeh, SS; Massad, IM, 2008) |
| " With respect to pain intensity, mean pain score was significantly less in the combination group than in the lidocaine or dexamethasone groups (P<0." | 5.13 | Efficacy of combination intravenous lidocaine and dexamethasone on propofol injection pain: a randomized, double-blind, prospective study in adult Korean surgical patients. ( Ha, J; Jeon, Y; Kim, Y; Kwak, KH, 2008) |
| "The use of intrarectal lidocaine gel did not demonstrated being more effective in pain control in our series than the use of lubricant gel, but lidocaine injected into the apex and seminal vesicles was." | 5.13 | [Ultrasound guided transrectal prostatic biopsy and pain. Prospective randomized study comparing lubricant gel, lidocaine gel, and anesthetic blockage of the neurovascular bundles with 1% lidocaine]. ( Argüelles Salido, E; Campoy Martínez, P; Conde Sánchez, JM; Congregado Ruiz, CB; Medina López, RA; Ruiz Zafra, V, 2008) |
| "Melatonin is an effective premedication before IVRA since it reduced patient anxiety, decreased tourniquet-related pain, and improved perioperative analgesia." | 5.13 | Melatonin improves tourniquet tolerance and enhances postoperative analgesia in patients receiving intravenous regional anesthesia. ( Ismail, SA; Mowafi, HA, 2008) |
| " To compare local anesthesia (1% lidocaine) with forced coughing as pain relief, we quantified the actual pain experienced during cervical punch biopsies." | 5.13 | Forced coughing versus local anesthesia and pain associated with cervical biopsy: a randomized trial. ( Hefler, L; Heinze, G; Pils, S; Reinthaller, A; Schmid, BC; Speiser, P, 2008) |
| "To determine whether the use of ethyl chloride and subcutaneous lidocaine are associated with a reduction in pain during arterial blood sampling compared with using no local anaesthesia." | 5.13 | Anaesthesia for arterial puncture in the emergency department: a randomized trial of subcutaneous lidocaine, ethyl chloride or nothing. ( Beech, FJ; Benger, JR; France, JE; Jakeman, N, 2008) |
| "We studied the effect of fentanyl pretreatment on alleviating pain during the injection of Propofol-Lipuro." | 5.13 | Fentanyl pre-treatment alleviates pain during injection of propofol-lipuro premixed with lignocaine. ( Ahmad, N; Balan, S; Zanariah, Y, 2008) |
| "To compare pain control results between periprostatic nerve block alone and combined with topical prilocaine-lidocaine cream as local anesthesia of prostate biopsy." | 5.13 | Topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial. ( Briganti, A; Dehò, F; Di Girolamo, V; Gallina, A; Montorsi, F; Raber, M; Rigatti, P; Roscigno, M; Salonia, A; Scattoni, V, 2008) |
| " acetaminophen seems to be effective in attenuating pain during i." | 5.13 | Efficacy of intravenous acetaminophen and lidocaine on propofol injection pain. ( Arun, O; Canbay, O; Celebi, N; Karagöz, AH; Ozgen, S; Saricaoğlu, F, 2008) |
| "Oral amitriptyline, a tricyclic antidepressant, is effective for treating neuropathic pain." | 5.13 | Topical amitriptyline versus lidocaine in the treatment of neuropathic pain. ( Ho, KY; Huh, BK; Miller, EJ; White, WD; Yeh, CC, 2008) |
| "Subjects receiving the needle-free powder lidocaine delivery system exhibited mean pain reductions (effect size) of 33% to 46% relative to sham placebo." | 5.13 | A novel needle-free powder lidocaine delivery system for rapid local analgesia. ( Leong, MS; Richards, PT; Robbins, B; Schechter, NL; Zempsky, WT, 2008) |
| "Skin infiltration with lidocaine, although brief, can be very stressful, painful, and may perpetuate anxiety." | 5.13 | Brief report: a randomized controlled trial of Synera versus lidocaine for epidural needle insertion in labouring parturients. ( Allen, TK; George, RB; Habib, AS; Muir, HA, 2008) |
| "The aim of this study was to compare the efficacy of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients." | 5.13 | Comparison of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, parallel-group, placebo-controlled study. ( Fujii, Y; Itakura, M, 2008) |
| "We compare the pain of intravenous (IV) cannulation in pediatric emergency department (ED) patients after applying a topical lidocaine/tetracaine patch versus placebo." | 5.13 | Warm lidocaine/tetracaine patch versus placebo before pediatric intravenous cannulation: a randomized controlled trial. ( Chipley, J; Chisena, EN; Gupta, N; Singer, AJ; Taira, BR, 2008) |
| "The Comparison of Venipuncture and Venous Cannulation Pain After Fast-Onset Needle-Free Powder Lidocaine or Placebo Treatment trial was a randomized, single-dose, double-blind, phase 3 study investigating whether a needle-free powder lidocaine delivery system (a sterile, prefilled, disposable system that delivers lidocaine powder into the epidermis) produces effective local analgesia within 1 to 3 minutes for venipuncture and peripheral venous cannulation procedures in children." | 5.13 | Needle-free powder lidocaine delivery system provides rapid effective analgesia for venipuncture or cannulation pain in children: randomized, double-blind Comparison of Venipuncture and Venous Cannulation Pain After Fast-Onset Needle-Free Powder Lidocaine ( Bean-Lijewski, J; Gennevois, DJ; Kauffman, RE; Koh, JL; Malviya, SV; Richards, PT; Rose, JB; Zempsky, WT, 2008) |
| " Mean +/- SD Modified Behavioral Pain Scale pain scores for EMLA, nitrous oxide/oxygen, and nitrous oxide/oxygen plus EMLA were, respectively, 9." | 5.13 | EMLA cream and nitrous oxide to alleviate pain induced by palivizumab (Synagis) intramuscular injections in infants and young children. ( Annequin, D; Biran, V; Carbajal, R; Cimerman, P; Epaud, R; Fauroux, B; Gold, F; Lenclen, R; Thibault, P, 2008) |
| "The aim of this randomized prospective and partially double-blind study was to evaluate the efficacy of transrectal lidocaine applied as suppositories in comparison to periprostatic infiltration as methods of reducing pain during transrectal prostate biopsy." | 5.13 | Comparison of lidocaine suppositories and periprostatic nerve block during transrectal prostate biopsy. ( Fink, KG; Gnad, A; Gotschl, R; Meissner, P; Paras, L; Schmeller, NT; Szlauer, R, 2008) |
| "To systematically and meta-analytically examine the efficacy of ropivacaine versus lidocaine infiltration for controlling postpartum perineal pain secondary to spontaneous tear or selective episiotomy." | 5.12 | Ropivacaine versus lidocaine infiltration for postpartum perineal pain: A systematic review and meta-analysis. ( Abu-Zaid, A; Abuzaid, M; Al-Badawi, IA; Alomar, O; Baradwan, S; Kadah, KA; Magzoub, D; Salem, H, 2021) |
| "A research was performed to review the effect of pharmacological interventions to control the propofol injection pain." | 5.12 | Pharmacological control of pain during propofol injection: a systematic review and meta-analysis. ( Bakhtiari, E; Gharavi Fard, M; Mousavi, SH, 2021) |
| " Additionally, hemodialysis patients exhibit reduced barrier function and can experience pain associated with repeated needle insertion; the repeated use of lidocaine tape to manage the pain can cause further skin damage." | 5.12 | Onset Mechanism and Pharmaceutical Management of Dry Skin. ( Ooi, K, 2021) |
| "Our purpose was to compare the pain induced by infiltration of the skin with 1% lidocaine with epinephrine 1:100,000 buffered with sodium bicarbonate (buffered) versus 1% lidocaine freshly mixed with epinephrine (fresh)." | 5.12 | Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine. ( Brown, MD; Burns, CA; Cooper, JZ; Feng, C; Ferris, G, 2006) |
| "Ketamine significantly reduced ongoing pain and evoked pain to brush and pinprick, whereas lidocaine only reduced evoked pain to repetitive pinprick stimuli." | 5.12 | Differential effect of ketamine and lidocaine on spontaneous and mechanical evoked pain in patients with nerve injury pain. ( Bach, FW; Gottrup, H; Jensen, TS; Juhl, G, 2006) |
| "To compare the level of pain experienced by patients during transrectal ultrasound-guided prostatic biopsy using intrarectal 2% lidocaine gel versus plain lubricant gel." | 5.12 | Intrarectal administration of lidocaine gel versus plain lubricant gel for pain control during transrectal ultrasound-guided extensive 10-core prostate biopsy in Hong Kong Chinese population: prospective double-blind randomised controlled trial. ( Cheung, MC; Ho, KL; Lee, FC; Leung, SY; Tam, PC; Wong, BB, 2006) |
| "To determine whether brief, focal pretreatment of children's skin with low-frequency ultrasound followed by a 5-minute application of a 4% lidocaine topical anesthetic decreases the pain of intravenous (IV) catheter placement." | 5.12 | Brief focal ultrasound with topical anesthetic decreases the pain of intravenous placement in children. ( Bates, A; Becker, BM; Lovgren, K; Minugh, PA; Skarbek-Borowska, S, 2006) |
| "To evaluate the effectiveness and acceptability of a lidocaine spray in reducing perineal pain during spontaneous vaginal delivery." | 5.12 | Effectiveness and acceptability of lidocaine spray in reducing perineal pain during spontaneous vaginal delivery: randomised controlled trial. ( Campbell, R; Peters, TJ; Sanders, J, 2006) |
| "Intrauterine lidocaine appears to be effective in decreasing pain in women undergoing the removal procedure of a "lost" IUD." | 5.12 | Efficacy of intrauterine lidocaine for removal of a "lost" intrauterine device: a randomized, controlled trial. ( Güney, M; Mungan, T; Oral, B, 2006) |
| "Previous studies found that lidocaine addition to propofol long-chain triglyceride was associated with a lower incidence of injection pain than medium-chain triglyceride/long-chain triglyceride formulation, but the incidence was still high (31-40%)." | 5.12 | Preventing pain during injection of propofol: effects of a new emulsion with lidocaine addition. ( Bachmann-Mennenga, B; Boedeker, RH; Heesen, M; Mann, M; Mühlenbruch, B; Ohlmer, A, 2007) |
| "Of the 4 methods studied, the optimal method to decrease the incidence and intensity of pain resulting from propofol injection is to inject lidocaine while applying venous occlusion for 60 seconds prior to administering propofol." | 5.12 | Venous occlusion with lidocaine for preventing propofol induced pain. A prospective double-blind randomized study. ( Abu-Ali, HM; Abu-Halaweh, SA; Badran, IZ; Massad, IM, 2006) |
| "The routine use of fentanyl and midazolam prior to sheath removal leads to a reduction in pain perception and vasovagal incidence, whilst the routine use of local infiltration during sheath removal should be discouraged as it leads to more pain and a trend to more vasovagal reactions." | 5.12 | Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention. ( French, JK; Juergens, CP; Kiat Ang, C; Leung, DY; Lo, S, 2007) |
| "Propofol is associated with a high incidence of injection pain in children, even if given together with lidocaine." | 5.12 | Etomidate-Lipuro is associated with considerably less injection pain in children compared with propofol with added lidocaine. ( Eksborg, S; Lönnqvist, PA; Nyman, Y; Palm, C; Von Hofsten, K, 2006) |
| "Administering 75 mg tramadol/650 mg acetaminophen orally with periprostatic 1% lidocaine before transrectal ultrasound guided prostate biopsy is a safe, easy and effective method of controlling pain during the biopsy procedure." | 5.12 | Combination of oral tramadol, acetaminophen and 1% lidocaine induced periprostatic nerve block for pain control during transrectal ultrasound guided biopsy of the prostate: a prospective, randomized, controlled trial. ( Carvin, DM; Costa, J; Pendleton, J; Rosser, CJ; Wludyka, P, 2006) |
| "To determine if topical gel is superior to subconjunctival injection of lidocaine in relieving pain of intravitreous injection of corticosteroid." | 5.12 | Topical gel vs subconjunctival lidocaine for intravitreous injection: a randomized clinical trial. ( Friedman, SM; Margo, CE, 2006) |
| " To evaluate the responsivity of the PQAS items to pain treatment, secondary analyses were conducted on data from a trial that compared the efficacy of lidocaine patch 5% versus a single steroid injection in 40 patients with carpal tunnel syndrome." | 5.12 | The pain quality assessment scale: assessment of pain quality in carpal tunnel syndrome. ( Galer, BS; Gammaitoni, AR; Jensen, MP; Nalamachu, SR; Olaleye, DO; Oleka, N, 2006) |
| "The present report evaluates the incidence of pain on intravenous injection and the condition of tracheal intubation at one minute following the administration of cisatracurium or rocuronium versus rocuronium-cisatracurium combination." | 5.12 | Cisatracurium or rocuronium versus rocuronium-cisatracurium combination. ( Baraka, A; Maaliki, H; Nahle, N; Zeidan, A, 2006) |
| "We examined the effect of lidocaine pretreatment before propofol administration on the incidence of transient motor disturbances and on propofol requirements for anesthesia induction in infants and children undergoing repeated painful diagnostic and therapeutic hematological procedures." | 5.12 | Lidocaine pretreatment for the prevention of propofol-induced transient motor disturbances in children during anesthesia induction: a randomized controlled trial in children undergoing invasive hematologic procedures. ( Annino, L; Bilotta, F; Favaro, R; Ferri, F; Rosa, G; Soriano, SG, 2006) |
| "To evaluate the influence of aging on lidocaine requirements for propofol-induced pain on injection." | 5.12 | Influence of aging on lidocaine requirements for pain on injection of propofol. ( Fujii, Y; Shiga, Y, 2006) |
| "To compare the pain of injection and biopsy when lidocaine is injected periprostatically either at a basal or apical site, as the former is commonly used to anaesthetise the prostate, based on several reports showing that it can eliminate most of the pain associated with prostate biopsy, and this site has been favoured over apical injection because the nerves enter the prostate from the basal aspect." | 5.12 | Comparison of traditional basal and apical periprostatic block: impact on injection pain and biopsy pain. ( Jones, JS; Nguyen, CT, 2007) |
| "Periprostatic lidocaine infiltration provides local anesthesia that results in improved visual analog scale pain scores." | 5.12 | Combined "periprostatic and periapical" local anesthesia is not superior to "periprostatic" anesthesia alone in reducing pain during Tru-Cut prostate biopsy. ( Akdas, A; Cevik, I; Dillioglugil, O; Zisman, A, 2006) |
| "To estimate whether an intracervical block of 1% lidocaine decreased pain perception compared with placebo during the performance of a hysterosalpingogram." | 5.12 | Intracervical block and pain perception during the performance of a hysterosalpingogram: a randomized controlled trial. ( Arthur, NA; Bates, GW; Casablanca, Y; Pagano, KE; Propst, AM; Robinson, RD, 2007) |
| "Previous injection of diphenhydramine with venous occlusion can be considered as an alternative to lidocaine for reducing the prevalence of pain caused by injection of propofol into peripheral veins." | 5.12 | Comparison of diphenhydramine and lidocaine for prevention of pain after injection of propofol: a double-blind, placebo-controlled, randomized study. ( Apiliogullari, B; Apiliogullari, S; Balasar, M; Duman, A; Keles, B; Yilmaz, H, 2007) |
| "35 microg kg(-1) min(-1)) and a premixture of lidocaine with propofol (mixture of propofol 1% and lidocaine 1% in a 10:1 ratio) was compared with either treatment alone in the prevention of pain on propofol injection." | 5.12 | Reduction of pain on injection of propofol: combination of pretreatment of remifentanil and premixture of lidocaine with propofol. ( Baek, W; Jeon, Y; Kim, J; Kim, S; Kwak, K; Lim, D; Park, S, 2007) |
| " The addition of epinephrine to lidocaine significantly reduced superficial bleeding." | 5.12 | Local infiltration of epinephrine-containing lidocaine with bicarbonate reduces superficial bleeding and pain during labor epidural catheter insertion: a randomized trial. ( Brummel, C; Carvalho, B; Cohen, SE; Fuller, A, 2007) |
| "To compare the efficacy and tolerance profile of saline-diluted botulinum toxin A and lidocaine-diluted botulinum toxin A in patients with axillary hyperhidrosis." | 5.12 | Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline: a randomized, side-by-side, double-blind study. ( Simonart, T; Vadoud-Seyedi, J, 2007) |
| " A statistically significant difference in pain scores was noted in premenopausal women during the procedure (lidocaine, 4." | 5.12 | Intrauterine lidocaine plus buccal misoprostol in the endometrial biopsy. ( Güney, M; Mungan, T; Oral, B, 2007) |
| "Topical application of EMLA and Oraqix before palatal anesthetic infiltration is associated with less pain than with benzocaine gel." | 5.12 | Comparison of topical anesthetics (EMLA/Oraqix vs. benzocaine) on pain experienced during palatal needle injection. ( Al-Melh, MA; Andersson, L, 2007) |
| "To compare the efficacy and side effects of transdermal diclofenac patch with eutectic mixture of local anesthetic (EMLA) cream in attenuating venous cannulation pain." | 5.12 | Transdermal diclofenac patch vs eutectic mixture of local anesthetics for venous cannulation pain. ( Agarwal, A; Gautam, S; Gupta, D; Singh, U, 2007) |
| "The aim of the study was to demonstrate that repeated anorectal administration of a 5% lidocaine ointment (CAS 137-58-6; LidoPosterine Salbe, Posterisan akut Rektalsalbe) in the treatment of patients with acute anorectal pain does not result in systemically efficacious plasma concentrations of lidocaine." | 5.12 | Proof of systemic safety of a lidocaine ointment in the treatment of patients with anorectal pain. ( Mazur, D; Schlegelmilch, R; Seiler, D; Vens-Cappell, B; Zimmermann, J, 2007) |
| "We conducted this randomized double-blind trial to determine the extent of further pain reduction by adding lidocaine to Lipuro propofol." | 5.12 | Lidocaine is more efficient than the choice of propofol formulations to reduce incidence of pain on induction. ( Elliot, SC; Krishnan, K; Mallick, A; Vucevic, M, 2007) |
| "A block randomised, non-blinded trial was performed to see if injecting lidocaine down a surgical drain could reduce the pain associated with its removal." | 5.12 | Randomised trial showing that lidocaine should be "squirted" through a peritoneal drain before it is removed. ( Jess, C; Johnson, N; Makins, A, 2007) |
| "To our knowledge, this is the first study demonstrating that the needle-free delivery of lidocaine is an effective, useful, and noninvasive method of providing local anesthesia for the FNAB of thyroid nodules." | 5.12 | Needle-free delivery of lidocaine for reducing the pain associated with the fine-needle aspiration biopsy of thyroid nodules: time-saving and efficacious procedure. ( Demirag, NG; Demirer, AN; Ertugrul, DT; Gursoy, A; Sahin, M; Tutuncu, NB, 2007) |
| "Topical lidocaine and epinephrine "sequential layered application" is an effective, safe, and less painful method of anesthesia for a wide variety of lacerations." | 5.12 | Expanding the use of topical anesthesia in wound management: sequential layered application of topical lidocaine with epinephrine. ( Gaufberg, SV; Walta, MJ; Workman, TP, 2007) |
| "The purpose of the present study was to evaluate clinically the effect of an anaesthetic gel (lidocaine 20 mg/g as active agent) on pain sensitivity and early wound healing following nonsurgical periodontal therapy." | 5.12 | Effectiveness of a topical salve (Dynexan) on pain sensitivity and early wound healing following nonsurgical periodontal therapy. ( Heib, A; Kasaj, A; Willershausen, B, 2007) |
| "The combination of two different analgesic modalities, remifentanil and lidocaine completely abolishes moderate and severe pain associated with propofol injection, and significantly reduces the incidence of mild pain when compared with each drug used alone." | 5.12 | Multimodal analgesia to prevent propofol-induced pain: pretreatment with remifentanil and lidocaine versus remifentanil or lidocaine alone. ( Al-Alami, AA; Aouad, MT; Baraka, AS; Siddik-Sayyid, SM, 2007) |
| "7%) complained of pain in the lidocaine plus remifentanil group compared with 15 (35." | 5.12 | A combination of lidocaine (lignocaine) and remifentanil reduces pain during propofol injection. ( Choi, G; Chung, H; Han, C; Jeon, Y; Kim, S; Kwak, K; Lim, C; Lim, D, 2007) |
| "Injection pain was twice as common with ketamine-propofol admixture than with lidocaine-propofol admixture." | 5.12 | A ketamine-propofol admixture does not reduce the pain on injection compared with a lidocaine-propofol admixture. ( Abdelaziz, AB; Cherif, R; Chettaoui, O; Kaabachi, O; Kokki, H; Ouezini, R, 2007) |
| "Pain on injection is a recognized adverse event (AE) with propofol, an agent used to induce general anesthesia in surgical patients." | 5.12 | Prevention of pain due to injection of propofol with IV administration of lidocaine 40 mg + metoclopramide 2.5, 5, or 10 mg or saline: a randomized, double-blind study in Japanese adult surgical patients. ( Fujii, Y; Nakayama, M, 2007) |
| "A prospective, double-blind, mixed, crossover study was conducted to determine the perception of pain associated with intradermal lidocaine and chloroprocaine for insertion of an 18-gauge intravenous catheter." | 5.12 | A study comparing chloroprocaine with lidocaine for skin infiltration before intravenous catheter insertion. ( Ales, R; May, D; Whitney, L, 2007) |
| "The incidence of pain on injection of propofol MCT/LCT was not different from that caused by propofol LCT with pretreatment of lidocaine and the intensity of pain on propofol MCT/LCT injection decreased significantly when using lidocaine pretreatment." | 5.12 | Pain on injection of propofol: propofol LCT vs propofol MCT/LCT with or without lidocaine pretreatment. ( Burimsittichai, R; Charuluxananan, S; Kumwilaisuk, K; Premsamran, P; Sathapanawath, N; Tingthanathikul, W, 2006) |
| " Lidocaine administration was the most painful element of the procedure, while probe insertion was the least." | 5.12 | Preventing pain during office biopsy of the prostate: a single center, prospective, double-blind, 3-arm, parallel group, randomized clinical trial. ( Ashley, RA; Blute, ML; Gettman, MT; Inman, BA; Krambeck, AE; Mynderse, LA; Routh, JC; Siddiqui, SA, 2007) |
| "We evaluated the efficacy of topical Myolaxin (capsaican ointment, Geno, Mumbai) ointment over EMLA (eutectic mixture of lignocaine, prilocaine; Neon, Goa) cream for attenuating venous cannulation pain in this prospective, randomised, double blind study." | 5.12 | Comparative evaluation of myolaxin and EMLA cream for attenuation of venous cannulation pain: a prospective, randomised, double blind study. ( Agarwal, A; Dhiraaj, S; Gupta, D; Singh, PK; Tandon, M; Yadav, G, 2007) |
| "Various strategies have been studied to reduce the discomfort of rocuronium pain." | 5.12 | Effect of narcotic pretreatment on pain after rocuronium injection: a randomized, double-blind controlled comparison with lidocaine. ( Bithal, PK; Chauhan, H; Dash, HH; Prabhakar, H; Rath, GP; Singh, M, 2007) |
| "Propofol, a commonly used anesthetic, often causes pain on injection." | 5.12 | Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine. ( Boker, A; Ertok, E; Saadawy, I, 2007) |
| " We evaluated the patient's perception of pain/discomfort experienced during the procedure in terms of the type of anesthesia used: periprostatic infiltration with 2% lidocaine, or intrarectal instillation of lidocaine-prilocain cream." | 5.11 | Pain during transrectal ultrasonography guided prostate biopsy: a randomized prospective trial comparing periprostatic infiltration with lidocaine with the intrarectal instillation of lidocaine-prilocain cream. ( Adamakis, I; Alamanis, C; Giannopoulos, A; Haritopoulos, K; Mitropoulos, D; Stravodimos, K, 2004) |
| "Pain on injection caused by Propofol-LCT with pre-treatment of lidocaine and Propofol-MCT/LCT alone is shown to be equivalent." | 5.11 | [Propofol-LCT versus propofol-MCT/LCT with or without lidocaine - a comparison on pain on injection]. ( Haaf-Von-Below, S; Kuhlen, R; Kunitz, O; Lösing, R; Rossaint, R; Schulz-Stübner, S, 2004) |
| "To investigate the effects of IV lidocaine on spontaneous and evoked pain (allodynia and hyperalgesia) due to peripheral nerve injury (postherpetic neuralgia or nerve trauma) using quantitative sensory testing." | 5.11 | Systemic lidocaine in pain due to peripheral nerve injury and predictors of response. ( Attal, N; Bouhassira, D; Brasseur, L; Chauvin, M; Rouaud, J, 2004) |
| "Intravenous magnesium and lidocaine pretreatment are equally effective in attenuating propofol-induced pain." | 5.11 | Vein pretreatment with magnesium sulfate to prevent pain on injection of propofol is not justified. ( Agarwal, A; Dhiraj, S; Gupta, D; Pandey, CK; Pandey, R; Raza, M; Singh, PK; Singh, U, 2004) |
| "The purpose of this prospective, randomized, double-blind study was to compare injection pain and postinjection pain of 2% lidocaine with 1:100,000 epinephrine and 3% mepivacaine using the computer-assisted Wand Plus injection system to administer the palatal-anterior superior alveolar (P-ASA) injection." | 5.11 | Injection pain and postinjection pain of the palatal-anterior superior alveolar injection, administered with the Wand Plus system, comparing 2% lidocaine with 1:100,000 epinephrine to 3% mepivacaine. ( Beck, M; Burns, Y; Nusstein, J; Reader, A; Weaver, J, 2004) |
| "Propofol causes pain on IV injection in 28%-90% of patients." | 5.11 | Pretreatment with thiopental for prevention of pain associated with propofol injection. ( Agarwal, A; Ansari, MF; Dhiraj, S; Gupta, D; Pandey, R; Raza, M; Singh, PK; Singh, U, 2004) |
| "Intravenous cannulation in children aged 6-12 years is less painful after a 90-min application of a Lidocaine/ Prilocaine cream followed by a 30-min interval without cream, than cannulation immediately after a 60-min application." | 5.11 | Improved application of Lidocaine/Prilocaine cream in children. A randomized and prospectively controlled study of two application regimes. ( Culmsee, M; Gad, LN; Lysgaard, AB; Olsen, KS, 2004) |
| "Ketamine but not lidocaine showed a significant analgesic effect in patients with neuropathic pain after spinal cord injury." | 5.11 | The analgesic effect of intravenous ketamine and lidocaine on pain after spinal cord injury. ( Gordh, T; Karlsten, R; Kvarnström, A; Quiding, H, 2004) |
| "During application of lidocaine, pain ratings were less for vaginal gel than paracervical block." | 5.11 | Lidocaine vaginal gel versus lidocaine paracervical block for analgesia during oocyte retrieval. ( Lee, C; Martin, J; Newton, C; Tummon, I, 2004) |
| "Periprostatic lidocaine infiltration and/or intravenous synthetic opioid analgesics are not beneficial in significantly reducing pain during biopsy." | 5.11 | Periprostatic lidocaine infiltration and/or synthetic opioid (meperidine or tramadol) administration have no analgesic benefit during prostate biopsy. A prospective randomized double-blind placebo-controlled study comparing different methods. ( Akbay, E; Atici, S; Bozlu, M; Canpolat, B; Cayan, S; Oral, U; Schellhammer, PF; Ulusoy, E, 2004) |
| "We found no difference in pain between the intrauterine-lidocaine and placebo groups." | 5.11 | The use of intrauterine lidocaine to minimize pain during hysterosalpingography: a randomized trial. ( Frishman, GN; Plosker, S; Shafi, F; Spencer, PK; Weitzen, S, 2004) |
| "To study the effects of an intrauterine lidocaine infusion on perceived patient pain in first-trimester abortions and to measure serum lidocaine levels." | 5.11 | Intrauterine lidocaine infusion for pain management in first-trimester abortions. ( Astley, S; Edelman, A; Jensen, JT; Leclair, C; Nichols, MD; Shy, K, 2004) |
| "To compare pain and discomfort ratings of female patients undergoing urethral catheterization randomized to topical application of plain lubricant versus lidocaine gel prior to the procedure." | 5.11 | Factors affecting pain scores during female urethral catheterization. ( Anderson, J; Johnson, D; Metcalf, S; Ring-Hurn, E; Steinmann, R; Tanabe, P, 2004) |
| "To clarify whether the therapeutic indication for a lidocaine patch to treat postherpetic neuralgia can be extended to include other focal peripheral neuropathic pain syndromes, we performed a subgroup analysis of a placebo-controlled, double-blind randomized study." | 5.11 | [Reduction of chronic pain for non-postherpetic peripheral neuropathies after topical treatment with a lidocaine patch]. ( Faust, M; Hüppe, M; Meier, T; Schmucker, P, 2004) |
| "This prospective, randomized study assessed the effectiveness of buffering lidocaine with sodium bicarbonate for reducing the pain associated with local anaesthetic infiltration for open carpal tunnel decompression." | 5.11 | Reducing the pain associated with local anaesthetic infiltration for open carpal tunnel decompression. ( Badras, LS; Paleochorlidis, I; Stavroulaki, P; Vossinakis, IC, 2004) |
| "The sub-Tenon's anaesthesia group and the lidocaine 2% jelly group did not vary significantly in subjective pain score (18." | 5.11 | Prospective study comparing lidocaine 2% jelly versus sub-Tenon's anaesthesia for trabeculectomy surgery. ( Buys, YM; Carrillo, MM; Faingold, D; Trope, GE, 2004) |
| "Propofol causes pain or discomfort on injection in 28%-90% of patients." | 5.11 | Pain during injection of propofol: the effect of prior administration of butorphanol. ( Agarwal, A; Dhiraaj, S; Gupta, D; Pandey, CK; Pandey, R; Raza, M; Singh, PK; Singh, U, 2004) |
| "Propofol is well known for its association with pain on injection." | 5.11 | Propofol-induced injection pain: comparison of a modified propofol emulsion to standard propofol with premixed lidocaine. ( Adam, S; Dirckx, M; Jonsson, D; Klein, J; Pelka, M; van Bommel, J, 2004) |
| "Although the equimolecular mixture of oxygen and nitrous oxide (EMONO) seems a good choice to relieve procedure-related pain in children, it has not been evaluated for insertion of central venous catheters in children." | 5.11 | Effectiveness of fixed 50% nitrous oxide oxygen mixture and EMLA cream for insertion of central venous catheters in children. ( Abdeladhim, AB; Abdelkefi, A; Abdennebi, YB; Aouf, S; Béjaoui, M; Ladeb, S; Mellouli, F; Othman, TB; Torjman, L, 2004) |
| " Subjects in the lidocaine infiltration group reported significantly more pain (mean, 4." | 5.11 | Reducing pain in ED patients during lumbar puncture: the efficacy and feasibility of iontophoresis, collaborative approach. ( Baumann, MR; Burton, JH; Jordan, PJ; Schultz, AA; Strout, TD; Worthing, B, 2004) |
| "To evaluate the efficacy of lidocaine tape in reducing pain during botulinum toxin injection." | 5.11 | Lidocaine tape (Penles) reduces the pain of botulinum toxin injection for Meige syndrome. ( Dogru, M; Onguchi, T; Ono, M; Takano, Y; Tsubota, K, 2004) |
| "To evaluate if dissolution of asparaginase in lidocaine can relieve pain of an intramuscular injection in children without changes in bioavailability." | 5.11 | Pain intensity and bioavailability of intramuscular asparaginase and a local anesthetic: a double-blinded study. ( Albertsen, BK; Clausen, N; Hasle, H; Jakobsen, P; Schrøder, H, 2005) |
| "A common drawback of propofol is pain on injection and lidocaine is commonly mixed with propofol to reduce its incidence and severity." | 5.11 | Comparison of Propofol-Lipuro with propofol mixed with lidocaine 10 mg on propofol injection pain. ( Abdul-Latif, MS; Kam, E; McCluskey, A, 2004) |
| "The incidence of pain on injection of propofol has been reported to be 70%." | 5.11 | Pain on injection: a double-blind comparison of propofol with lidocaine pretreatment versus propofol formulated with long- and medium-chain triglycerides. ( Kern, C; Landau, R; Schaub, E, 2004) |
| "To determine the impact of the lidocaine patch 5% on distinct pain qualities associated with osteoarthritis (OA) through use of the Neuropathic Pain Scale (NPS), an assessment tool designed to assess intensity of various pain qualities (i." | 5.11 | Lidocaine patch 5% and its positive impact on pain qualities in osteoarthritis: results of a pilot 2-week, open-label study using the Neuropathic Pain Scale. ( Argoff, CE; Galer, BS; Gammaitoni, AR; Jensen, MP; Onawola, R, 2004) |
| "To determine the effectiveness of lidocaine-adrenaline-tetracaine (LAT) in providing adequate anesthesia for the repair of finger lacerations and to monitor the risk of digital ischemia following application of LAT gel to finger lacerations." | 5.11 | The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations. ( Bergholte, J; Brousseau, DC; Hennes, H; Kim, MK; White, NJ, 2004) |
| "To investigate the analgesic efficacy and safety of 5% lidocaine gel in painful HIV-associated distal sensory polyneuropathy (DSP)." | 5.11 | A randomized controlled trial of 5% lidocaine gel for HIV-associated distal symmetric polyneuropathy. ( Carter, K; Estanislao, L; McArthur, J; Olney, R; Simpson, D, 2004) |
| "Intravesical treatment with combined heparin and alkalinized lidocaine immediately reduced the pain and urgency of IC in most patients treated for newly diagnosed IC." | 5.11 | Successful downregulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis. ( Parsons, CL, 2005) |
| "The use of 40% DMSO with lidocaine instilled into the rectal vault for 10 minutes avoids any need for injection and is capable of decreasing the discomfort or pain experienced during probe insertion and prostate biopsy comparable to the perianal and periprostatic protocols." | 5.11 | Comparison of different local anesthesia techniques during TRUS-guided biopsies: a prospective pilot study. ( Ben-Dor, D; Cytron, S; Dorfman, D; Kesari, D; Kravchick, S; Peled, R, 2005) |
| "A randomized double-blind study compared two methods of preventing the pain from injection of propofol, lignocaine pre-treatment followed by propofol and lignocaine added to propofol." | 5.11 | Preventing pain on injection of propofol: a comparison between lignocaine pre-treatment and lignocaine added to propofol. ( Lee, P; Russell, WJ, 2004) |
| ") ketamine sedation administered by nonanesthetist physicians for painful procedures." | 5.11 | Intravenous ketamine sedation for painful oncology procedures. ( Barbour, K; Evans, D; Kobe, J; Montgomery, CJ; Rogers, P; Turnham, L; Vandebeek, C; Wilson, L, 2005) |
| ", Salt Lake City, UT), a eutectic mixture of lidocaine and tetracaine, for pain relief during venipuncture in children." | 5.11 | A randomized controlled trial to evaluate S-Caine patch for reducing pain associated with vascular access in children. ( Berde, CB; Hannallah, RS; Sethna, NF; Solodiuk, JC; Verghese, ST; Zurakowski, D, 2005) |
| " We studied its efficacy in decreasing the pain associated with IV administration of propofol and compared it with mixing lidocaine with propofol." | 5.11 | Bacteriostatic saline containing benzyl alcohol decreases the pain associated with the injection of propofol. ( Minogue, SC; Sun, DA, 2005) |
| " Lidocaine EMDA is superior to alkalized lidocaine in that it allows for a greater distention of the bladder for a longer period of time but does not eliminate the pain of bladder distention." | 5.11 | Pilot study of the feasibility of in-office bladder distention using electromotive drug adminstration (EMDA). ( Azevedo, K; Payne, CK; Rose, AE, 2005) |
| "To compare the pain induced by outpatient flexible cystoscopy in men having local lidocaine jelly application or plain lubricant." | 5.11 | Randomized double-blind comparison of lidocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy. ( Chen, YT; Hsiao, PJ; Hsieh, CH; Wang, CC; Wong, WY; Yang, SS, 2005) |
| "The SonoPrep ultrasound device applied to skin for 15 seconds followed by 5 minutes of 4% liposomal lidocaine cream significantly reduced patients' perception of the pain of an IV start when compared with standard care." | 5.11 | Ultrasound with topical anesthetic rapidly decreases pain of intravenous cannulation. ( Baker, E; Becker, BM; Helfrich, S; Lovgren, K; Machan, JT; Minugh, PA, 2005) |
| "Twenty-four spinal cord injury patients with neuropathic pain at or below the level of injury were randomized and completed a double-blind crossover trial of 5 mg/kg lidocaine and placebo infused over 30 min." | 5.11 | Intravenous lidocaine relieves spinal cord injury pain: a randomized controlled trial. ( Bach, FW; Biering-Sørensen, F; Finnerup, NB; Jensen, TS; Johannesen, IL; Juhl, GI; Kristensen, AD; Sindrup, SH; Terkelsen, AJ, 2005) |
| "To compare the efficacy of topical eutectic mixture of local anesthetics (EMLA) versus topical lidocaine (LMX) in pain control for Nd:YAG 1,064 nm laser hair removal." | 5.11 | Direct comparison of EMLA versus lidocaine for pain control in Nd:YAG 1,064 nm laser hair removal. ( Guardiano, RA; Norwood, CW, 2005) |
| "25 patients (83%) complained of pain in the placebo group, compared with 12 (40%) in the lidocaine group (P < 0." | 5.11 | A lidocaine/metoclopramide combination decreases pain on injection of propofol. ( Fujii, Y; Nakayama, M, 2005) |
| " lidocaine and nitrous oxide (N2O) in oxygen (O2) inhalation pre-treatment was compared with either treatment alone in the prevention of pain on propofol injection." | 5.11 | A combination of lidocaine and nitrous oxide in oxygen is more effective in preventing pain on propofol injection than either treatment alone. ( Elsaigh, I; Galvin, E; Harmon, D; Leonard, I; Niazi, A; Wahid, Z, 2005) |
| "A new MCT-LCT propofol formulation as a plain solution was associated with a higher incidence of injection pain than LCT propofol with added lidocaine when used for induction of anaesthesia in children." | 5.11 | Propofol injection pain in children: a prospective randomized double-blind trial of a new propofol formulation versus propofol with added lidocaine. ( Eksborg, S; Georgiadi, A; Lönnqvist, PA; Nyman, Y; von Hofsten, K, 2005) |
| "Propofol formulated in medium- and long-chain triglycerides (MCT/LCT) is thought to cause less pain on injection." | 5.11 | The effects of intravenous lidocaine on pain during injection of medium- and long-chain triglyceride propofol emulsions. ( Chong, SY; Goh, MH; Tan, KH; Yew, WS, 2005) |
| "In a randomized, double-blind, prospective trial we compared the efficacy of pre-treatment with nitrous oxide (with or without premixed lignocaine in propofol) for the prevention of propofol-induced pain." | 5.11 | Effect of nitrous oxide in reducing pain of propofol injection in adult patients. ( Neema, PK; Rathod, RC; Sinha, PK, 2005) |
| "Use of liposomal lidocaine was associated with a higher intravenous cannulation success rate, less pain, shorter total procedure time and minor dermal changes among children undergoing cannulation." | 5.11 | Liposomal lidocaine to improve procedural success rates and reduce procedural pain among children: a randomized controlled trial. ( Koren, G; Schuh, S; Scolnik, D; Soin, HK; Taddio, A, 2005) |
| "Patients receiving lidocaine gel experienced statistically less pain than the lidocaine injection group for mean VAS 1 (0." | 5.11 | Which anaesthesia should be recommended for prostate biopsy? ( Blanchet, P; Braud, F; Clervil, M; Fofana, M; Humbert, M; Mallick, S, 2005) |
| "To compare intraoperative pain responses following intraovarian versus mesovarian injection of lidocaine in mares undergoing laparoscopic ovariectomy." | 5.11 | Intraoperative pain responses following intraovarian versus mesovarian injection of lidocaine in mares undergoing laparoscopic ovariectomy. ( Farstvedt, EG; Hendrickson, DA, 2005) |
| " The mean pain of cannulation after laser-assisted lidocaine application (13 mm, 95% CI = 8 to 19) was significantly less than after application of sham laser (29 mm, 95% CI = 22 to 36; mean difference, 15 mm, 95% CI = 6 to 24)." | 5.11 | Laser-assisted anesthesia prior to intravenous cannulation in volunteers: a randomized, controlled trial. ( Regev, R; Singer, AJ; Tlockowski, DS; Weeks, R, 2005) |
| "5% are significantly more effective than 20% benzocaine in reducing pain from needle stick in the maxillary vestibular mucosa." | 5.11 | Reduction of pain from needle stick in the oral mucosa by topical anesthetics: a comparative study between lidocaine/prilocaine and benzocaine. ( Abu Al-Melh, M; Andersson, L; Behbehani, E, 2005) |
| "The pretreatment with nitrous oxide is a time effective and safe method for use at paediatric outpatient departments to reduce pain, facilitate venous cannulation, and thereby reduce the number of costly cancellations of planned procedures." | 5.11 | Nitrous oxide inhalation is a safe and effective way to facilitate procedures in paediatric outpatient departments. ( Ekbom, K; Jakobsson, J; Marcus, C, 2005) |
| "We conducted a randomized, double-blind, placebo-controlled trial comparing pain scores during bladder catheterization with 2% lidocaine gel versus nonanesthetic lubricant." | 5.11 | Does lidocaine gel alleviate the pain of bladder catheterization in young children? A randomized, controlled trial. ( Bush, A; Paton, EA; Pershad, J; Vaughan, M, 2005) |
| "Intrarectal diclofenac suppository administration is a simple, safe, and effective procedure to reduce pain and improve patients' tolerance of transrectal ultrasound-guided prostate biopsy." | 5.11 | Diclofenac suppository administration in conjunction with lidocaine gel during transrectal ultrasound-guided prostate biopsy: prospective, randomized, placebo-controlled study. ( Aslan, G; Celebi, I; Goktay, Y; Gulcu, A; Irer, B, 2005) |
| "The numbers of patients with severe and mild pain were larger in the order: LCT group (10 and 31 patients, respectively) > flurbiprofen 1 group (3 and 19) > or = MCT/LCT group (1 and 14) > or = lidocaine group (2 and 11) > flurbiprofen group (0 and 0)." | 5.11 | How to decrease pain at rapid injection of propofol: effectiveness of flurbiprofen. ( Nishiyama, T, 2005) |
| "Topical anaesthesia with prilocaine-lidocaine cream significantly reduced pain at transrectal probe insertion and during the biopsy procedure." | 5.11 | Perianal and intrarectal anaesthesia for transrectal biopsy of the prostate: a prospective randomized study comparing lidocaine-prilocaine cream and placebo. ( Montorsi, F; Raber, M; Rigatti, P; Roscigno, M; Scattoni, V, 2005) |
| "To determine whether preprocedural application of lidocaine 4% topical anesthetic cream to the injection site will reduce pain on injection of BTX-A for the treatment of crow's feet." | 5.11 | Single-center, double-blind, randomized study to evaluate the efficacy of 4% lidocaine cream versus vehicle cream during botulinum toxin type A treatments. ( Carruthers, A; Carruthers, J, 2005) |
| "Pain on injection, reported in 28-90% of patients, is one of the most described side effects of the intravenous application of propofol." | 5.11 | Comparison on pain on injection of a small particle size-lipid emulsion of propofol and standard propofol with or without lidocaine. ( Diregpoke, S; Krobbuaban, B; Kumkeaw, S; Tanomsat, M, 2005) |
| "Topical lidocaine-prilocaine (EMLA) effectively decreases the pain associated with minor procedures including immunization, although the effect on the antibody response to diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b conjugate (DTaP-IPV-Hib) and hepatitis B vaccines has not been assessed." | 5.10 | Use of lidocaine-prilocaine patch to decrease intramuscular injection pain does not adversely affect the antibody response to diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b conjugate and hepatitis B vaccines in ( Halperin, BA; Halperin, SA; Houston, T; McGrath, P; Smith, B, 2002) |
| " This study is the first to examine the adult medical inpatient pain response associated with peripheral IVC for patients receiving subcutaneous buffered lidocaine 1%, subcutaneous normal saline 0." | 5.10 | Comparison of intravenous cannulation injectable preanesthetics in an adult medical inpatient population. ( Hattula, JL; McGovern, EK; Neumann, TL, 2002) |
| "05) less painful than either lidocaine hydrochloride or diphenhydramine and equivalent to placebo." | 5.10 | Comparison of effects of lidocaine hydrochloride, buffered lidocaine, diphenhydramine, and normal saline after intradermal injection. ( Chen, E; McSweeney, TD; Reilley, TE; Tibbits, DL; Xia, Y, 2002) |
| "The use of intrarectal lidocaine is not superior to placebo during transrectal prostate biopsy for pain control." | 5.10 | Lack of effect of intrarectal lidocaine for pain control during transrectal prostate biopsy: a randomized prospective study. ( Akdaş, A; Cevik, I; Dillioglugil, O; Ozveri, H, 2002) |
| "Comparing the combined lidocaine preparations to placebo, there was a statistically significant reduction in pain when the LAD was employed (P < 0." | 5.10 | Laser assisted delivery of topical anesthesia for intramuscular needle insertion in adults. ( Bar-Or, D; Harris, L; Hetzel, FW; Shapiro, H, 2002) |
| "To evaluate patients' perceptions and preferences concerning pain control during intravenous (IV) catheterization, a sample of 50 adult patients received subcutaneous lidocaine (0." | 5.10 | Subcutaneous lidocaine delivered by jet-injector for pain control before IV catheterization in the ED: the patients' perception and preference. ( Frasure, HE; Peter, DJ; Scott, JP; Watkins, HC, 2002) |
| "Although it is well-known that 2% lidocaine has an effective action for preventing propofol-induced pain, it has been unclear whether or not lidocaine of the concentration below 2% has the effective action similar to 2% lidocaine." | 5.10 | [Effects of concentration and dosage of lidocaine on preventing the pain on injection of propofol]. ( Adachi, H; Harada, T; Hirosawa, J; Inagaki, Y; Ishibe, Y; Otsuki, A; Tsubokura, H, 2002) |
| "We compared the ability of metoclopramide with IV lidocaine pretreatment to abolish pain from a diazepam injection." | 5.10 | A comparison of metoclopramide and lidocaine for preventing pain on injection of diazepam. ( Hassannasab, B; Khan, ZH; Majedi, H; Rabiee, M, 2002) |
| " Based on the clinical evidence of pain alleviation by topical morphine in patients with some inflammatory and painful conditions, a clinical study was undertaken to determine this effect on mucositis-associated pain." | 5.10 | Effect of topical morphine for mucositis-associated pain following concomitant chemoradiotherapy for head and neck carcinoma. ( Bonomi, MR; Cerchietti, LC; Menéndez, PR; Navigante, AH; Pogany, CE; Roth, BM; Zaderajko, MA, 2002) |
| "We conducted a randomized, double blinded, placebo controlled trial to evaluate the effectiveness of EMLA cream together with intraperitoneal lidocaine for pain relief in postpartum tubal ligation." | 5.10 | EMLA cream and intraperitoneal lidocaine decrease intraoperative pain during postpartum tubal sterilization. ( Apidechakul, P; Ariyanon, P; Latthikaviboon, U; Limsakul, A; Parakkamodom, S; Permpolprasert, L; Pethpaisit, N; Santivarangkana, T; Sirilertmakasakul, P; Visalyaputra, S, 2002) |
| "Pain scores were significantly lower using the novel lidocaine/tetracaine-based cream peel formulation compared with the EMLA cream." | 5.10 | Evaluation of a novel topical anesthetic agent for cutaneous laser resurfacing: a randomized comparison study. ( Alster, TS; Lupton, JR, 2002) |
| "To estimate the efficacy of lidocaine ointment in relieving pain after a vaginal delivery with an episiotomy or perineal laceration." | 5.10 | Randomized trial of lidocaine ointment versus placebo for the treatment of postpartum perineal pain. ( Jazayeri, A; Minassian, VA; Prien, SD; Stumbo, K; Timmons, RL, 2002) |
| "To investigate if 50% nitrous oxide reduces the pain during injection of propofol mixed with lidocaine in children." | 5.10 | In children, nitrous oxide decreases pain on injection of propofol mixed with lidocaine. ( Beh, T; Kim, J; Splinter, W, 2002) |
| "The pain and distress ratings of patients undergoing BMAs (n = 73) and LPs (n = 105) were examined in a comparison of 3 different interventions: (1) a topical eutectic mixture of lidocaine and prilocaine (EMLA cream), (2) oral midazolam and EMLA cream, or (3) propofol/fentanyl general anesthesia." | 5.10 | Pain and distress from bone marrow aspirations and lumbar punctures. ( Doran, NH; Frost, JD; Holdsworth, MT; Mathew, P; Moro, MA; Pankey, JM; Phillips, J; Raisch, DW; Winter, SS, 2003) |
| "To determine whether topical 2% lignocaine (lidocaine) gel is an effective anaesthetic agent for chalazion surgery." | 5.10 | Efficacy of lignocaine 2% gel in chalazion surgery. ( Lai, JS; Lam, DS; Lau, EM; Law, RW; Li, RT; Ng, JS, 2003) |
| "The objectives of this study were to compare the incidence, onset, duration and pain scores of transient neurologic symptoms (TNS) with 1% versus 5% hyperbaric lidocaine in spinal anesthesia for short urological procedures in a large prospective study." | 5.10 | Prospective study on incidence and functional impact of transient neurologic symptoms associated with 1% versus 5% hyperbaric lidocaine in short urologic procedures. ( Bremang, J; Chung, F; Friedlander, M; Mezei, G; Streiner, D; Tong, D; Wong, J, 2003) |
| "When compared with rocuronium alone, only the addition of saline failed to significantly reduce the pain reported by patients." | 5.10 | Comparison of four strategies to reduce the pain associated with intravenous administration of rocuronium. ( Chiarella, AB; Clanachan, AS; Huston, CM; Jolly, DT, 2003) |
| "To evaluate the efficacy of eutectic lidocaine/prilocaine cream (EMLA) in reducing the pain associated with steroid joint injection in children with juvenile arthritis." | 5.10 | Evaluation of eutectic lidocaine/prilocaine cream (EMLA) for steroid joint injection in children with juvenile rheumatoid arthritis: a double blind, randomized, placebo controlled trial. ( Berkovitch, M; Gazarian, M; Koren, G; Laxer, RM; Schneider, R; Silverman, ED; Uziel, Y, 2003) |
| " Without analgesia (control) 26 of 45 patients (58%) reported pain on injection compared with 11 of 45 patients (24%) in both the nitrous oxide (95% CI: 14-52%, P = 0." | 5.10 | Nitrous oxide/oxygen mixture and the prevention of pain during injection of propofol. ( Harmon, D; Lowe, D; Rozario, C, 2003) |
| "25 microg x kg(-1) x min(-1) with 40 mg lidocaine and placebo in the prevention of injection pain due to intravenous propofol administration (1." | 5.10 | Prevention of propofol-induced injection pain by remifentanil: a placebo-controlled comparison with lidocaine. ( Boldt, J; Maleck, WH; Piper, SN; Roehm, KD, 2003) |
| "Injection of lidocaine resulted in a reduction in pain scores for cervical biopsies (4." | 5.10 | Local anesthetic reduces the pain of colposcopic biopsies: a randomized trial. ( Frattarelli, LC; Kessel, B; Oyama, IA; Wakabayashi, MT, 2003) |
| "We compared the effect of lidocaine injection with lidocaine iontophoresis for pain relief during radial artery cannulation prior to induction of anaesthesia." | 5.10 | Analgesia during radial artery cannulation: comparison of the effects of lidocaine applied by local injection or iontophoresis. ( Awad, IT; Liddle, AM; Rowbotham, DJ; Sadler, PJ; Sherwin, J, 2003) |
| "Pain is often experienced when propofol is injected, and intravenous lidocaine is often effective in preventing such pain." | 5.10 | Pain on injection of propofol: comparison of metoprolol with lidocaine. ( Aşik, I; Gülay, I; Tulunay, M; Yörükoğlu, D, 2003) |
| "The objective of this study is to determine whether use of lidocaine-prilocaine 5% cream (EMLA) and oral glucose decreases pain associated with diphteria-pertussis-tetanus (DPT) immunization in 3-month-old infants." | 5.10 | EMLA cream and oral glucose for immunization pain in 3-month-old infants. ( Blomquist, HK; Håkansson, S; Lindh, V; Wiklund, U, 2003) |
| "In terms of pain control, lidocaine 2% gel alone is a superior topical anesthetic for one-stage adjustable suture strabismus surgery when compared with amethocaine 1% eyedrops." | 5.10 | Comparison of lidocaine 2% gel versus amethocaine as the sole anesthetic agent for strabismus surgery. ( Fan, DS; Lam, DS; Wong, VW; Yip, WW; Yu, CB, 2003) |
| "Lidocaine is used to reduce pain associated with propofol injection, either mixed with propofol or preceding it as a separate injection." | 5.10 | The effect of mixing lidocaine with propofol on the dose of propofol required for induction of anesthesia. ( Hwang, NC; Tan, LH, 2003) |
| "We compared the efficacy of magnesium sulphate, lignocaine, sodium bicarbonate or alfentanil in minimizing pain due to injection of rocuronium in 250 patients." | 5.10 | The prevention of pain from injection of rocuronium by magnesium sulphate, lignocaine, sodium bicarbonate and alfentanil. ( Karamanlioglu, B; Memis, D; Pamukcu, Z; Sut, N; Turan, A, 2003) |
| "The authors conducted this study to compare the pain on injection of the three mandibular block techniques and to determine the effect that the delivery of nitrous oxide:oxygen, or N2O:O2, had on this pain." | 5.10 | Injection pain: comparison of three mandibular block techniques and modulation by nitrous oxide:oxygen. ( Haas, DA; Jacobs, S; May, S; Meechan, JG, 2003) |
| "Topical anesthesia using 60% lidocaine tape reduces the incidence of propofol injection pain." | 5.10 | The efficacy of 5% lidocaine-prilocaine (EMLA) cream on pain during intravenous injection of propofol. ( Currer, BA; McCluskey, A; Sayeed, I, 2003) |
| "In order to investigate external factors that may influence the magnitude of placebo analgesia as well as psychological factors that mediate placebo analgesia, 13 irritable bowl syndrome (IBS) patients rated evoked rectal distension and cutaneous heat pain under the conditions of natural history (NH), rectal placebo (RP), rectal nocebo (RN), rectal lidocaine (RL) and oral lidocaine (OL)." | 5.10 | The contributions of suggestion, desire, and expectation to placebo effects in irritable bowel syndrome patients. An empirical investigation. ( Price, DD; Robinson, ME; Vase, L; Verne, GN, 2003) |
| " Six patients who received contact-topical anaesthesia reported mild discomfort during delivery of the anaesthetic agent, while 43 patients complained of mild to severe pain during the injection of bupivacaine (p < 0." | 5.10 | Contact versus peribulbar anaesthesia in trabeculectomy: a prospective randomized clinical study. ( Ferreras, A; Gómez, ML; Honrubia, FM; Pablo, LE; Pérez-Oliván, S; Polo, V, 2003) |
| "Pain scores with piroxicam gel were higher on cannulation and on advancement of the cannula (P < 0." | 5.10 | Piroxicam gel, compared to EMLA cream is associated with less pain after venous cannulation in volunteers. ( Dutta, A; Puri, GD; Wig, J, 2003) |
| "Data from the 2 trials showed that there was a 62% pain reduction with laser pretreatment plus lidocaine compared with laser pretreatment plus placebo, and a 61% pain reduction with laser pretreatment plus lidocaine, compared with lidocaine alone." | 5.10 | Laser-assisted penetration of topical anesthetic in adults. ( Bar-Or, D; Baron, ED; Harris, L; Hetzel, F; Morley, G; Redpath, WS; Shapiro, H; Stevens, SR, 2003) |
| "The incidence of pain of the infusion was significantly lower in patients pretreated with ketamine (8% vs 37%, P = 0." | 5.10 | Pretreatment with intravenous ketamine reduces propofol injection pain. ( Barbi, E; Gagliardo, A; Gerarduzzi, T; Marchetti, F; Neri, E; Sarti, A; Ventura, A, 2003) |
| "To assess the effectiveness and safety of the lidocaine patch 5%, a targeted peripheral analgesic, in the treatment of postherpetic neuralgia, painful diabetic neuropathy, and low back pain patients with incomplete responses to their current analgesic treatment regimen containing gabapentin." | 5.10 | Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain. ( Drass, M; Nalamachu, S; Patel, N; White, WT, 2003) |
| "Using 2-chloroprocaine can diminish pain caused by the intradermal injection of lidocaine." | 5.10 | Chloroprocaine is less painful than lidocaine for skin infiltration anesthesia. ( Janosky, JE; Marica, LS; Nystrom, EU; O'Day, T, 2002) |
| "The purpose of this study was to determine whether lidocaine that is instilled onto the Fallopian tubes reduces pain scores in awake patients who undergo laparoscopic sterilization with Filshie clips." | 5.10 | Tubal surface lidocaine mediates pre-emptive analgesia in awake laparoscopic sterilization: a prospective, randomized clinical trial. ( Garwood, S; Guillebaud, J; Mackenzie, IZ; Reeder, M, 2002) |
| "In this randomized, double-blinded, placebo-controlled study, we evaluated the safety and efficacy of lidocaine iontophoresis for the prevention of pain associated with venipuncture in 59 children aged 6-17 yr." | 5.10 | A study of lidocaine iontophoresis for pediatric venipuncture. ( Chiavacci, RM; Galinkin, JL; Jantzen, EC; Rose, JB, 2002) |
| "We compared the efficacy of ondansetron, lidocaine, tramadol, and fentanyl in minimizing pain caused by the injection of rocuronium in 250 patients." | 5.10 | The prevention of pain from injection of rocuronium by ondansetron, lidocaine, tramadol, and fentanyl. ( Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Süt, N; Turan, A, 2002) |
| "To compare the effects of nitrous oxide with lidocaine on pain on injection caused by propofol in children." | 5.10 | [Prevention of pain on injection with propofol in children: comparison of nitrous oxide with lidocaine]. ( Ecoffey, C; Geslot, D; Lembert, N; Wodey, E, 2002) |
| "A double-randomized, blinded crossover trial was performed to assess the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics (EMLA) for pain relief during pediatric venipuncture procedures." | 5.10 | A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children. ( Cunningham, BB; Eichenfield, LF; Fallon-Friedlander, S; Funk, A, 2002) |
| "The iontophoretic application of lidocaine was compared with intravenous lidocaine to assess the relative efficacy of reducing pain during propofol administration." | 5.10 | Iontophoretically applied lidocaine and the prevention of pain associated with the injection of intravenous propofol: a comparison with intravenous lidocaine. ( Asif, M; Rowbotham, DJ; Sharpe, P; Victoria, A, 2002) |
| "The mean pain scores, comparing responses from groups 2 (topical lidocaine) and 3 (periprostatic) individually with those from group 1 (control), were not statistically different for any of the preprocedural questions." | 5.10 | Comparison of local anesthesia techniques during transrectal ultrasound-guided biopsies. ( Carothers, GG; Maatman, TJ; Shockley, KF; Stirling, BN, 2002) |
| "To determine whether the application of a eutectic mixture of anesthetic cream (EMLA cream) can decrease the pain of lidocaine injection during vasectomy." | 5.10 | Use of EMLA cream with vasectomy. ( Cooper, TP, 2002) |
| "This multicentre, double-blind, placebo-controlled, parallel-group study assessed the efficacy and safety of using Emla (lignocaine/prilocaine) anaesthetic cream to achieve pain control during sharp debridement of chronic leg ulcers of arterial, venous or arteriovenous aetiology." | 5.09 | Using a topical anaesthetic cream to reduce pain during sharp debridement of chronic leg ulcers. ( Baxter, M; Gottschalk, R; Lycka, B; Murphy, F; Nevin, K; Rosenthal, D, 2001) |
| " retention of metoclopramide with tourniquet is as good as lidocaine and may be a useful alternative for reducing pain on propofol injection." | 5.09 | Pain on injection of propofol: the mitigating influence of metoclopramide using different techniques. ( Chang, DP; Hwang, MH; Liaw, WJ; Pang, WW, 1999) |
| " The injection of these agents is often associated with pain, and it is not uncommon for sclerotherapists to include lidocaine with the sclerosants in an attempt to reduce the pain associated with treatment." | 5.09 | Evaluation of lidocaine as an analgesic when added to hypertonic saline for sclerotherapy. ( Bukhari, RH; Cranley, RD; Hearn, AT; Lohr, JM; Paget, DS, 1999) |
| "Pain on injection of rocuronium in pediatric patients can be alleviated by pretreatment with i." | 5.09 | The use of lidocaine for preventing the withdrawal associated with the injection of rocuronium in children and adolescents. ( Choudhry, DK; Jocson, JC; McRae, VA; Rehman, M; Schwartz, RE; Shevchenko, Y; Stayer, SA, 1999) |
| "Nine patients with Complex Regional Pain Syndrome types I and/or II (CRPS), previously known as reflex sympathetic dystrophy (RSD) and causalgia, respectively, were selected for treatment with a continuous four to eight week subcutaneous infusion of 10% lidocaine." | 5.09 | Subcutaneous infusion of lidocaine provides effective pain relief for CRPS patients. ( Linchitz, RM; Raheb, JC, 1999) |
| "We conducted a randomized, double-blinded, placebo-controlled trial to evaluate the effectiveness of intraperitoneal lidocaine, IM morphine, or both drugs together for pain relief in postpartum tubal ligation." | 5.09 | Intraperitoneal lidocaine decreases intraoperative pain during postpartum tubal ligation. ( Lertakyamanee, J; Parakkamodom, S; Pethpaisit, N; Somprakit, P; Suwanapeum, P; Visalyaputra, S, 1999) |
| "To compare efficacy and cost of lidocaine cutaneous anesthesia by two jet injectors to routine needle infiltration for pain relief of intravenous (i." | 5.09 | Painless intravenous catheterization by intradermal jet injection of lidocaine: a randomized trial. ( Darby, P; Goll, EF; Koenig, HM; Zsigmond, EK, 1999) |
| "This study investigated the effect of intravenous lidocaine at two doses (1 mg/kg and 5 mg/kg over 2 hours) and an intravenous saline placebo on the pain and allodynia of postherpetic neuralgia (PHN)." | 5.09 | A trial of intravenous lidocaine on the pain and allodynia of postherpetic neuralgia. ( Baranowski, AP; Bonello, E; De Courcey, J, 1999) |
| "We have compared iontophoretically and locally applied lidocaine for relief of pain on propofol injection." | 5.09 | Iontophoretically applied lidocaine reduces pain on propofol injection. ( Liddle, A; Maslowski, P; Rowbotham, DJ; Sadler, PJ; Thompson, HM, 1999) |
| "Lidocaine-prilocaine cream (EMLA) is currently standard therapy to alleviate procedural pain in children." | 5.09 | Relative efficacy of amethocaine gel and lidocaine-prilocaine cream for Port-a-Cath puncture in children. ( Bar-Oz, B; Bishai, R; Freedman, MH; Koren, G; Taddio, A, 1999) |
| "To determine the optimal concentration of lidocaine that reduces pain on injection of a propofol-lidocaine mixture." | 5.09 | The optimal effective concentration of lidocaine to reduce pain on injection of propofol. ( Chu, CC; Ho, CM; Lee, TY; Sun, MS; Tsou, MY, 1999) |
| "The purpose of this study was to compare the effect of premixed 5% dextrose in Ringer's acetate solution and premixed lidocaine with propofpl on the reduction of pain during injection of propofol in adult patients." | 5.09 | [Premixing of 5% dextrose in Ringer's acetate solution with propofol reduces incidence and severity of pain on propofol injection]. ( Kashimoto, S; Kumazawa, T; Nonaka, A; Oguchi, T; Sugawara, T; Tamaki, F, 1999) |
| " The pain which occurs as a response to an intravenous injection of Propofol is one of the main obstacles to its use as an anesthetic." | 5.09 | [Administration of propofol. Addition of lidocaine eases the pain]. ( Fernández, V; Hernández, S; López, S; Santamaría, R, 1999) |
| "The efficacy of lignocaine-prilocaine cream (EMLA) and amethocaine gel (Ametop) in reducing the pain and distress of venepuncture was compared in a single-blind randomized study of 34 children aged 1-14 y." | 5.09 | Comparison of lignocaine-prilocaine cream and amethocaine gel for local analgesia before venepuncture in children. ( Choy, L; Collier, J; Watson, AR, 1999) |
| "To compare the effectiveness of a steroid injection (25 mg/ml prednisolone acetate) with a local anaesthetic control in the treatment of heel pain and to determine any advantage for patients' comfort of using a posterior tibial nerve block to anesthetize the heel prior to infiltration." | 5.09 | Steroid injection for heel pain: evidence of short-term effectiveness. A randomized controlled trial. ( Atkins, D; Crawford, F; Edwards, J; Young, P, 1999) |
| " Prilocaine plus lidocaine cream was more effective than lidocaine spray in decreasing pain at placement of the tenaculum and shoulder pain after the procedure." | 5.09 | Topical anesthesia for office hysteroscopy. A prospective, randomized study comparing two modalities. ( Di Carlo, C; Fabrizio, A; Nappi, C; Pellicano, M; Stigliano, CM; Zullo, F, 1999) |
| "To evaluate whether alkalizing local anesthetic with sodium bicarbonate reduces pain related to infiltration of local anesthetic during dorsal penile nerve block for circumcision." | 5.09 | Alkalinizing local anesthetic does not decrease pain during injection for dorsal penile nerve block. ( Ben Yehuda, Y; Boaz, M; Levine, A; Mandelberg, A; Mori, J; Serour, F, 1999) |
| "Intravenous lidocaine and diphenhydramine had no significant effect on the cool, warm, or cold pain thresholds." | 5.09 | Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II. ( Gerayli, A; Leung, AY; Ridgeway, BM; Wallace, MS; Yaksh, TL, 2000) |
| "To test the hypothesis that adjunctive intracameral 1% lidocaine reduces intraoperative pain during phacoemulsification using topical anesthesia." | 5.09 | A randomized controlled trial of intracameral lidocaine during phacoemulsification under topical anesthesia. ( Baer, RM; Boulton, JE; Lopatatzidis, A; Luck, J, 2000) |
| "To elucidate the mechanism of propofol-induced pain on injection, we performed several studies using nafamostat mesilate, a kallikrein inhibitor, or lidocaine." | 5.09 | A potential mechanism of propofol-induced pain on injection based on studies using nafamostat mesilate. ( Iwama, H; Nakane, M, 1999) |
| "A randomised, prospective trial was conducted to assess the efficacy of various means of alleviating the pain of subcutaneous lidocaine infiltration." | 5.09 | Towards a pain-free venepuncture. ( Koay, CK; Lim, NL; Ong, EL, 2000) |
| "To investigate the effects of systemic administration of lidocaine on different components of neuropathic central pains by quantitative sensory testing." | 5.09 | Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study. ( Attal, N; Bouhassira, D; Brasseur, L; Dupuy, M; Gaudé, V; Guirimand, F; Parker, F, 2000) |
| "To determine the efficacy of intrauterine lidocaine for decreasing pain associated with endometrial biopsy using the Pipelle instrument (Unimar; Wilton, CT)." | 5.09 | Anesthetic efficacy of intrauterine lidocaine for endometrial biopsy: a randomized double-masked trial. ( Fishburne, C; McGrady, S; Trolice, MP, 2000) |
| "A prospective, randomized, double-blind study was conducted to determine whether cooled intravenous propofol reduces the incidence of pain on induction of anaesthesia in children." | 5.09 | Propofol and pain on induction: the effect of injectate temperature in children. ( Burden, J; Lewis, I; Pickford, A, 2000) |
| "We have assessed the incidence of pain on injection of rocuronium and evaluated if pretreatment with lidocaine i." | 5.09 | Pain on injection of rocuronium: influence of two doses of lidocaine pretreatment. ( Cheong, KF; Wong, WH, 2000) |
| "Pain of circumcision is only partially relieved by single modalities, such as penile nerve block, lidocaine-prilocaine cream, and sucrose pacifiers." | 5.09 | Combined analgesia and local anesthesia to minimize pain during circumcision. ( Gilbert-MacLeod, C; Koren, G; Ohlsson, K; Pollock, N; Taddio, A, 2000) |
| "This investigation evaluated the use and efficacy of prilocaine HCl (4% plain Citanest) for minimizing pain associated with the intraoral administration of local anesthesia." | 5.09 | Evaluation of prilocaine for the reduction of pain associated with transmucosal anesthetic administration. ( Eleazer, PD; Kramp, LF; Scheetz, JP, 1999) |
| "Although effective in neuropathic pain, the efficacy of systemic lidocaine in non-neuropathic pain remains uncertain." | 5.09 | The effect of systemic lidocaine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers. ( Dahl, JB; Dirks, J; Fabricius, P; Petersen, KL; Rowbotham, MC, 2000) |
| "A mixture of 40 mg of triamcinolone acetonide and 1 ml of 2 percent lidocaine was injected into the tenderest point transanally in 104 patients (33 males; mean age, 51 years) with levator syndrome from December 1996 to May 1998 at Daehang Clinic." | 5.09 | Transanally injected triamcinolone acetonide in levator syndrome. ( Cho, HJ; Jeong, SY; Kang, YS; Kim, DS; Kim, TS; Lee, DH, 2000) |
| "Our goal was to perform a pilot study to assess the effectiveness and tolerability of a topical lidocaine patch (Lidoderm) for the treatment of peripheral neuropathic pain conditions other than postherpetic neuralgia." | 5.09 | Topical lidocaine patch relieves a variety of neuropathic pain conditions: an open-label study. ( Devers, A; Galer, BS, 2000) |
| "The mean pain score for the prilocaine group was 1." | 5.09 | Prilocaine versus lignocaine for minor lid procedures. ( Backhouse, O; Burton, AJ; Metcalfe, TW, 2000) |
| "There was minimal change in the degree of pain in the lidocaine-only and control groups during and after the treatment period." | 5.09 | Intrathecal methylprednisolone for intractable postherpetic neuralgia. ( Asai, M; Hashimoto, H; Kimura, F; Kotani, N; Kushikata, T; Matsuki, A; Muraoka, M; Yodono, M, 2000) |
| "Analgesic efficacy of repeated application of a lidocaine cream formula was investigated in herpes zoster patients with subacute pain with no further improvement after continued treatment since their acute stage (S-HZ group, n = 23), and in patients to whom past treatments had not provided adequate pain relief (PHN group, n = 28)." | 5.09 | [Relief of subacute herpetic pain and postherpetic neuralgia with repeated application of 10% lidocaine cream]. ( Iseki, M; Mitsuhata, H; Miyazaki, T; Toriumi, E; Yoshino, K, 2000) |
| "The purpose of this study was to compare the younger and older patients in the incidence and the severity of the pain during injection of propofol." | 5.09 | [Effect of pre-mixed lidocaine with propofol on propofol injection pain in elderly patients]. ( Kumazawa, T; Nonaka, A; Suzuki, M; Suzuki, S; Tamaki, F, 2000) |
| " Supplemental lidocaine was then infiltrated through the wound edges and the pain of infiltration was recorded by the patient (or guardian) on a 100-mm visual analog scale marked "most pain" at the high end." | 5.09 | LET versus EMLA for pretreating lacerations: a randomized trial. ( Singer, AJ; Stark, MJ, 2001) |
| "To compare the relative efficacy of oral sucrose versus EMLA cream for pain relief during venepuncture, 51 full-term newborns (38M, 13F; postnatal age <4 d) in a stable condition were randomly allocated to one of four treatment groups: placebo (2 ml spring water); 2 ml sucrose 24% w/v; 1 g lidocaine-prilocaine 5% cream (EMLA); or EMLA plus sucrose." | 5.09 | Oral sucrose compares favourably with lidocaine-prilocaine cream for pain relief during venepuncture in neonates. ( Abad, F; Díaz-Gómez, NM; Domenech, E; Feria, M; González, D; Robayna, M, 2001) |
| "Injection of lidocaine lateral to the seminal vesicles before prostate biopsy did not diminish biopsy-associated pain." | 5.09 | Effect of local anesthetics on patient recovery after transrectal biopsy. ( Carter, HB; Fleisher, LA; Naqibuddin, M; Wu, CL, 2001) |
| "Pain generated by needle sticks (Ns) for the delivery of local anesthetic and/or scaling and root planing (SRP) instrumentation is commonly addressed by the use of topical anesthetics, such as a benzocaine-gel preparation (BGP)." | 5.09 | Clinical evaluation and comparison of 2 topical anesthetics for pain caused by needle sticks and scaling and root planing. ( Carr, MP; Horton, JE, 2001) |
| "To determine whether epidural lidocaine reduces the severity of propofol injection pain compared with iv lidocaine." | 5.09 | Epidural anesthesia with lidocaine reduces propofol injection pain. ( Inoue, T; Ogawa, R; Ogura, A; Wajima, Z; Yoshikawa, T, 2001) |
| "The objective of this study was to explore the relation between the application of a mixture of lidocaine/prilocaine cream (eutectic mixture of local anesthetics [EMLA]) before intravenous cannula insertion and perceived pain in the pediatric patient." | 5.09 | Eutectic mixture of local anesthetics reduces pain during intravenous catheter insertion in the pediatric patient. ( Cordoni, A; Cordoni, LE, 2001) |
| "Propofol is frequently associated with pain on injection." | 5.09 | Role of tramadol in reducing pain on propofol injection. ( Cheong, KF; Wong, WH, 2001) |
| "In a randomised, controlled, double-blinded trial to study the effect of ondansetron pretreatment on the pain produced after intravenous injection of rocuronium and propofol in comparison with lidocaine, 60 patients were randomly assigned to one of three groups." | 5.09 | Effect of ondansetron pretreatment on pain after rocuronium and propofol injection: a randomised, double-blind controlled comparison with lidocaine. ( Chen, FG; Ng, HP; Reddy, MS, 2001) |
| "To compare the efficiency of lidocaine with that of plain saline for paracervical pain relief during fractional curettage." | 5.09 | Lidocaine versus plain saline for pain relief in fractional curettage: a randomized controlled trial. ( Chanrachakul, B; Herabutya, Y; Likittanasombut, P; O-Prasertsawat, P, 2001) |
| "The effectiveness of lidocaine and benzocaine in reducing pain produced by needle insertion into the palate was evaluated in a double-blind and placebo-controlled study using a more suitable method." | 5.09 | Clinical effectiveness of lidocaine and benzocaine for topical anesthesia. ( Lavrador, MA; Rosa, AL; Sverzut, CE; Xavier, SP, 1999) |
| "To evaluate differences in pain, photophobia, retinal and optic nerve function in test eyes given intracameral lidocaine compared with control eyes given intracameral saline after phacoemulsification under topical anesthesia." | 5.09 | Pain, photophobia, and retinal and optic nerve function after phacoemulsification with intracameral lidocaine. ( Fujimoto, DK; Pang, MP; Wilkens, LR, 2001) |
| "The least pain on cystoscopy occurred in patients receiving 20 mL of gel containing lidocaine." | 5.09 | Flexible cystoscopy: is the volume and content of the urethral gel critical? ( Holmes, M; Rice, M; Stewart, J, 2001) |
| "To investigate the effect of simultaneous bolus injection of 2% lidocaine 2 ml on preventing the pain on propofol injection, 80 patients were randomly assigned to one of four study groups; Group I received simultaneous bolus injection of 2% lidocaine 2 ml with infusion of propofol; Group II received bolus injection of saline 2 ml, 10 s before the start of infusion of propofol-lidocaine mixture; Groups III and IV received bolus injections of lidocaine and saline, separately 10 s before starting propofol infusion." | 5.09 | [Efficacy of simultaneous bolus injection of lidocaine with propofol on pain caused by propofol injection]. ( Adachi, H; Harada, T; Hirosawa, J; Inagaki, Y; Ishibe, Y; Otsuki, A; Tsubokura, H, 2001) |
| "The effectiveness of a eutectic mixture lidocaine-prilocaine topical anaesthetic cream (EMLA) patch compared with a placebo patch in the reduction of pain associated with intramuscular immunization was evaluated." | 5.09 | A randomized double-blind, placebo-controlled trial of the EMLA patch for the reduction of pain associated with intramuscular injection in four to six-year-old children. ( Brown, TL; Cassidy, KL; Finley, GA; McGrath, PJ; Reid, GJ; Smith, DJ, 2001) |
| "To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes." | 5.08 | The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial. ( Delaney, G; Heck, C; Janzen, V; McCain, GA; Russell, AL; Scudds, RA; Teasell, RW; Varkey, G; Woodbury, GM, 1995) |
| "To determine whether warming of lidocaine decreases the pain of its injection during digital nerve block." | 5.08 | Randomized double-blind controlled trial comparing room-temperature and heated lidocaine for digital nerve block. ( Quinn, JV; Stiell, IG; Waldbillig, DK; Wells, GA, 1995) |
| "CSB with lidocaine and bupivicaine, but not saline, reduced spontaneous pain and light sensitivity and increased production of tears." | 5.08 | A controlled trial of regional sympatholysis in the treatment of photo-oculodynia syndrome. ( Digre, KB; Fine, PG, 1995) |
| "Phase 1: ibuprofen reduced pain scores more than placebo with the improvement being greatest for the postoperative period." | 5.08 | Pain control in abortion. ( Rawling, M; Wiebe, ER, 1995) |
| "The efficacy of a eutectic mixture of local anesthetics (EMLA) in alleviating the pain associated with subcutaneous needle insertion for infusion of the iron-chelating agent, deferoxamine, was examined in 12 patients with homozygous beta-thalassemia." | 5.08 | Use of a eutectic mixture of local anesthetics for prolonged subcutaneous drug administration. ( Berkovitch, M; Davis, S; Donsky, J; Koren, G; Matsui, D; Olivieri, NF, 1995) |
| "To compare pain on infiltration, need for additional anesthesia, and pain on suturing in patients given plain, warm, and buffered lidocaine preparations before the suturing of traumatic wounds in the emergency department." | 5.08 | Comparison of plain, warmed, and buffered lidocaine for anesthesia of traumatic wounds. ( Brogan, GX; Cassara, G; Giarrusso, E; Hollander, JE; Maranga, MC; Thode, HC, 1995) |
| "To determine whether topical lidocaine attenuates the pain of buffered lidocaine infiltration." | 5.08 | Does topical lidocaine attenuate the pain of infiltration of buffered lidocaine? ( Bartfield, JM; Raccio-Robak, N; Salluzzo, RF, 1995) |
| " Buffering lidocaine with sodium bicarbonate significantly reduced pain scores reported by 46 women who participated in this randomized, double-blind study." | 5.08 | Neutralizing pH of lidocaine reduces pain during Norplant system insertion procedure. ( Nelson, AL, 1995) |
| "Use of intradermal buffered lidocaine is an effective way to diminish the pain of i." | 5.08 | Buffered lidocaine: analgesia for intravenous line placement in children. ( Klein, EJ; Koepsell, T; Leigh-Taylor, K; Portscheller, D; Schneider, C; Shugerman, RP, 1995) |
| "Lidocaine 1% can be safely and usefully combined with intracorporeal prostaglandin E1 in the treatment of erectile dysfunction with alleviation of pain and enhancement of erectile effect." | 5.08 | Double-blind randomized crossover study comparing intracorporeal prostaglandin E1 with combination of prostaglandin E1 and lidocaine in the treatment of organic impotence. ( Kattan, S, 1995) |
| " Topical anesthesia patients were administered nebulized 4% lidocaine (approximately 20 ml) via the oropharynx plus a transtracheal injection of 4% lidocaine (3 ml)." | 5.08 | A comparison of anesthetic techniques for awake intubation in neurosurgical patients. ( Hunt, SW; Kirchner, J; Reasoner, DK; Todd, MM; Warner, DS, 1995) |
| "Propofol, which is commonly used for outpatient anaesthesia, may evoke pain during infusion." | 5.08 | Prilocaine reduces injection pain caused by propofol. ( Eriksson, M, 1995) |
| "Pain is a well known complication of propofol injection." | 5.08 | Modulating effects of lignocaine on propofol. ( Khoo, ST; Tham, CS, 1995) |
| "Two hundred and seventy-eight patients scheduled for all types of surgery and premedicated with diazepam and metoclopramide were randomly allocated to one of four groups to compare the relative pain of an injection of 0." | 5.08 | Rationalizing venepuncture pain: comparison of lignocaine injection, Butterfly (21 gauge and 23 gauge) and Venflon (20 gauge). ( Prabhu, NV; Van den Berg, AA, 1995) |
| " Our aim was to compare EMLA and placebo to assess the efficacy of EMLA in decreasing the pain of venipuncture in children premedicated with oral midazolam 0." | 5.08 | [Efficacy of the EMLA cream in the reduction of pain caused by venipuncture in children premedicated with oral midazolam]. ( Cassinello, F; de Stefano, J; Herrero, E; Martín-Celemín, R; Palencia, J; Pérez-Gallardo, A, 1995) |
| "This study investigated propofol injection pain in patients undergoing ambulatory anaesthesia." | 5.08 | Thiopentone pretreatment for propofol injection pain in ambulatory patients. ( Haugen, RD; Merrick, PM; Vaghadia, H; Waters, T, 1995) |
| "Mean visual analog scale pain scores were not different between the two types of blocks: 3 cm for lidocaine/bupivacaine and for bupivacaine alone (P = ." | 5.08 | Comparison of bupivacaine and lidocaine/bupivacaine for local anesthesia/digital nerve block. ( Leffler, S; Valvano, MN, 1996) |
| "Pain intensity, muscle strength, static muscle endurance, pressure pain threshold, and pain tolerance at tender points and control points were assessed in 31 patients with fibromyalgia (FM), before and after intravenous administration of morphine (9 patients), lidocaine (11 patients), and ketamine (11 patients)." | 5.08 | Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine. ( Bäckman, E; Bengtsson, A; Bengtsson, M; Henriksson, KG; Sörensen, J, 1995) |
| "We undertook a randomized, placebo-controlled, double-blind study to compare the use of alfentanil 1 mg and lidocaine 40 mg for the reduction of pain during injection of propofol." | 5.08 | Prevention of pain on injection of propofol: a comparison of lidocaine with alfentanil. ( Gajraj, NM; Nathanson, MH; Russell, JA, 1996) |
| "The most frequent complaint noted with the use of lidocaine (or other amide local anesthetic) is stinging or burning pain associated with subcutaneous infiltration." | 5.08 | Does warming local anesthetic reduce the pain of subcutaneous injection? ( Jones, JS; Martin, S; Wynn, BN, 1996) |
| "9% saline (1 ml) on a double-blind basis, as pretreatment to reduce pain on injection of propofol." | 5.08 | Modification of pain on injection of propofol. A comparison of pethidine and lignocaine. ( Flynn, C; Lohan, D; Lyons, B; McCarroll, M, 1996) |
| "This study was performed in order to determine concentration-effect, and graded and quantal dose-response relationships for the clinical administration of intravenous (IV) lidocaine to patients with neuropathic pain." | 5.08 | The analgesic response to intravenous lidocaine in the treatment of neuropathic pain. ( Arthur, GR; Cherukuri, S; Ferrante, FM; Paggioli, J, 1996) |
| "Three calcium (Ca) channel antagonists were administered to healthy adult volunteers by iontophoresis alone or in combination with lidocaine to study their effects on the pain threshold." | 5.08 | The effect of calcium channel antagonist administered by iontophoresis on the pain threshold. ( Honda, N; Miyagawa, A; Mizutani, A; Oyama, T; Taniguchi, K, 1995) |
| "In an observer blind study, the efficacy of lignocaine-prilocaine eutectic mixture was established in alleviating the pain of needle insertion during retrobulbar and periorbital tissues block in cataract surgery." | 5.08 | EMLA prevents pain during local anesthesia for cataract surgery. ( Dovinou, K; Nastou, H; Pappa, X; Pouliou, K; Stamatiou, I, 1995) |
| "Twenty patients with chronic pain who previously had obtained analgesia from epidural clonidine and lignocaine agreed to participate in a double-blind crossover study of lumbar epidural clonidine (150 micrograms), lignocaine (40 mg) and the combination of clonidine (150 microgram) and lignocaine (40 mg), all drugs were given in a volume of 3 ml." | 5.08 | A double-blind randomised comparison of the effects of epidural clonidine, lignocaine and the combination of clonidine and lignocaine in patients with chronic pain. ( Glynn, C; O'Sullivan, K, 1996) |
| "We evaluated the effect of lidocaine containing adhesive tape (LT) on the venipuncture pain by using visual analogue scale (VAS)." | 5.08 | [Skillfulness is essential to improve venipuncture pain in combination with lidocaine containing adhesive tape]. ( Nakao, M; Onji, I, 1996) |
| " Eleven patients suffering from neuropathic pain after peripheral nerve injury received both a lidocaine and saline infusion in separate study sessions." | 5.08 | Computer-controlled lidocaine infusion for the evaluation of neuropathic pain after peripheral nerve injury. ( Dyck, BJ; Rossi, SS; Wallace, MS; Yaksh, TL, 1996) |
| "We have investigated if alfentanil acts via peripheral opioid receptors to relieve the pain which occurs on injection of propofol." | 5.08 | Alfentanil-mediated analgesia during propofol injection: no evidence for a peripheral action. ( Girling, KJ; Hobbs, GJ; Wrench, IJ, 1996) |
| "A randomised, controlled, single-blind study was performed on 100 patients to investigate a new method of reducing pain on propofol injection." | 5.08 | Injection pain with propofol. Reduction with aspiration of blood. ( Jameson, P; McDonald, DS, 1996) |
| "A randomised, double-blind, controlled trial was undertaken to compare three different methods of reducing pain during the intravenous injection of propofol." | 5.08 | The effect of pretreatment with ketorolac on pain during intravenous injection of propofol. ( Power, I; Smith, AJ, 1996) |
| "The results of this study indicate that the preoperative injection of intrawound morphine in combination with the local anesthetic both promotes bleeding and has an early pain-enhancing effect while providing no late analgesic benefit beyond that of IM morphine." | 5.08 | The combination of morphine with local anaesthetic in rhinoplasty--no evidence of a peripheral morphine effect. ( Ben-David, B; Moscona, RA; Stahl, S, 1996) |
| "To define the optimal dose of lidocaine to be added to propofol to reduce the incidence of pain during its injection." | 5.08 | Preventing pain during injection of propofol: the optimal dose of lidocaine. ( Gajraj, NM; Nathanson, MH, 1996) |
| "To determine whether topical tetracaine attenuates the pain of buffered lidocaine infiltration." | 5.08 | Topical tetracaine attenuates the pain of infiltration of buffered lidocaine. ( Asher, SL; Bartfield, JM; Lee, FS; Raccio-Robak, N; Salluzzo, RF, 1996) |
| "To determine whether subcutaneous lidocaine (SQL), when used to decrease the pain of IV catheter insertion, adversely affects IV access in children < 24 months of age." | 5.08 | Subcutaneous lidocaine does not affect the success rate of intravenous access in children less than 24 months of age. ( Carraccio, C; Sacchetti, AD, 1996) |
| "5% prilocaine) in reducing distress, anxiety, and pain associated with phlebotomy in pediatric outpatients." | 5.08 | EMLA cream as a topical anesthetic before office phlebotomy in children. ( Schwartz, R; Sheridan, MJ; Young, SS, 1996) |
| "There is no clear evidence that intraurethral lidocaine jelly decreases pain and/or makes rigid cystoscopy more tolerable for patients." | 5.08 | Randomized, prospective, double-blind study of the effects on pain perception of lidocaine jelly versus plain lubricant during outpatient rigid cystoscopy. ( Cromie, WJ; Gerber, GS; Goldfischer, ER; Karrison, TG; Naszkiewicz, L, 1997) |
| "To compare the local efficacy of lidocaine and fentanyl in reducing propofol injection pain (PIP), we conducted a prospective randomized double-blind study in 75 ASA I and II adult patients." | 5.08 | Reduction of propofol pain--fentanyl vs lidocaine. ( Alyafi, WA; Rangasami, J, 1996) |
| "To evaluate the effect of buffered lidocaine with self reporting of pain elicited during maxillary labial and palatal infiltrations of permanent canines." | 5.08 | Pain elicited during intraoral infiltration with buffered lidocaine. ( Primosch, RE; Robinson, L, 1996) |
| "The use of a topical anesthetic cream containing prilocaine and lidocaine (EMLA) has been considered to reduce the pain of diagnostic allergy skin testing, but the effects of the cream on interpretation of skin tests is unclear." | 5.08 | EMLA cream for pain reduction in diagnostic allergy skin testing: effects on wheal and flare responses. ( Eggleston, PA; Sicherer, SH, 1997) |
| "The efficacy of tetracaine cream versus that of lidocaine-prilocaine cream for the prevention of pain in children undergoing venipuncture was studied." | 5.08 | Tetracaine versus lidocaine-prilocaine for preventing venipuncture-induced pain in children. ( Egberts, AC; Lenderink, AW; Rijnvos, WP; ter Pelkwijk, NJ; van Kan, HJ, 1997) |
| "To investigate the efficacy of lidocaine tape, a new preparation of lidocaine for cutaneous topical anaesthesia in the form of a self-adhesive tape, in alleviating the pain of needle insertion during stellate ganglion block." | 5.08 | Lidocaine tape relieves pain due to needle insertion during stellate ganglion block. ( Inada, K; Inada, T; Kawachi, S; Uesugi, F, 1997) |
| ") lidocaine and topical nitroglycerin ointment in preventing pain during propofol injection." | 5.08 | Effects of topical nitroglycerin and intravenous lidocaine on propofol-induced pain on injection. ( Beven, M; Carpenter, T; Laseter, JT; Mascha, E; Maurer, WG; O'Hara, JR; Sprung, J, 1997) |
| "Lidocaine-prilocaine cream is efficacious and safe for the prevention of pain from circumcision in neonates." | 5.08 | Efficacy and safety of lidocaine-prilocaine cream for pain during circumcision. ( Ben-David, S; Craig, K; Koren, G; Mulligan, P; Rastogi, P; Shennan, A; Stevens, B; Taddio, A, 1997) |
| " However, administration of topical bupivacaine was significantly less painful than peribulbar injections (P < ." | 5.08 | Patient comfort during cataract surgery with modified topical and peribulbar anesthesia. ( Burton, T; Maclean, H; Murray, A, 1997) |
| "The purpose of this study was to confirm the effect of premixed lidocaine for the reduction of pain during injection of propofol in adult patients." | 5.08 | [Premixing lidocaine reduces the incidence and severity of pain on injection of propofol]. ( Akazawa, S; Fukuda, H; Inoue, S; Kasuda, H; Kawakami, T; Konishi, R; Mitsuhata, H; Saitoh, J; Saitoh, K; Shimizu, R; Suzuki, H, 1997) |
| "Pain is a well known complication of propofol injection." | 5.08 | [Effect of lidocaine administration mode on decreasing injection pain caused by propofol]. ( Bornscheuer, A; Goldmann, R; Kirchner, E, 1997) |
| "Propofol has the disadvantage of pain on injection." | 5.08 | Effect of lignocaine and pH on propofol-induced pain. ( Englesson, S; Eriksson, M; Hartvig, P; Niklasson, F, 1997) |
| "We evaluated whether lidocaine tape (3 X 5 cm, contained 18 mg of lidocaine) could reduce pain caused by venous cannulation in children during anesthetic induction." | 5.08 | [Efficacy of lidocaine tape for venous cannulation in children]. ( Fukuda, M; Kitamura, Y; Nagata, N; Satani, M; Takaki, O, 1997) |
| " This study demonstrates that, when used in conjunction with DPNB, a pacifier dipped in 24% sucrose and a more comfortable, padded, and physiologic restraint can be useful in decreasing distress and pain." | 5.08 | Beyond dorsal penile nerve block: a more humane circumcision. ( Brodersen, L; Condon, LM; Conroy, MM; Gunnar, MR; Liebo, R; Snellman, LW; Stang, HJ, 1997) |
| "The objective of the study was to compare topical lidocaine adrenaline tetracaine (LAT gel) with injectable buffered lidocaine with epinephrine regarding pain of application or injection and anesthesia effectiveness." | 5.08 | Topical lidocaine adrenaline tetracaine (LAT gel) versus injectable buffered lidocaine for local anesthesia in laceration repair. ( Ernst, AA; Houry, D; Marvez-Valls, E; Mills, T; Minvielle, L; Nick, TG, 1997) |
| "We determined whether pretreatment with topical 60% lidocaine tape reduced the incidence of pain on injection of propofol compared with mixing intravenous lidocaine with propofol." | 5.08 | Pretreatment with topical 60% lidocaine tape reduces pain on injection of propofol. ( Hosoda, R; Kimura, T; Komatsu, T; Komura, Y; Nishiwaki, K; Shimada, Y; Yokota, S, 1997) |
| "We investigated the influence of preanesthetic medication on the pain relieving effect of the lidocaine tape during needle insertion for venous cannulation." | 5.08 | [Influence of preanesthetic medication on the effect of a local anesthetic tape]. ( Horikawa, Y; Kagawa, T; Kondo, M; Obara, H; Ohnishi, H, 1997) |
| "To determine the impact of administration rate and buffering on the pain associated with subcutaneous infiltration of lidocaine." | 5.08 | Pain of local anesthetics: rate of administration and buffering. ( Gracely, EJ; Jasani, M; Scarfone, RJ, 1998) |
| "Intraoral lidocaine patches have recently been approved by the US Food and Drug Administration for the production of topical anesthesia before superficial dental procedures and for the reduction of pain associated with local anesthetic injections." | 5.08 | An evaluation of intraoral lidocaine patches in reducing needle-insertion pain. ( Heins, P; Houpt, MI; Lamster, I; Stone, C; Wolff, MS, 1997) |
| " pretreatment with fentanyl, morphine, meperidine, or lidocaine in reducing propofol injection pain." | 5.08 | The analgesic effect of fentanyl, morphine, meperidine, and lidocaine in the peripheral veins: a comparative study. ( Huang, S; Hwang, MH; Mok, MS; Pang, WW, 1998) |
| "Despite current clinical practice, there is no objective evidence to demonstrate the efficacy or pain on injection when hyaluronidase is added to lidocaine as an anesthetic combination for local anesthesia." | 5.08 | The effects of hyaluronidase on the efficacy and on the pain of administration of 1% lidocaine. ( Nevarre, DR; Tzarnas, CD, 1998) |
| "To define the relationship between order of injection and pain of infiltration of buffered lidocaine." | 5.08 | The effect of order on pain of local anesthetic infiltration. ( Bartfield, JM; Pauze, D; Raccio-Robak, N, 1998) |
| "Propofol is frequently associated with pain on injection." | 5.08 | Pain on injection of propofol. A comparison of cold propofol with propofol premixed with lignocaine. ( Koay, CK; Parmar, AK, 1998) |
| ") retention of fentanyl and lidocaine in reducing the pain on i." | 5.08 | Comparison of intravenous retention of fentanyl and lidocaine on local analgesia in propofol injection pain. ( Chang, DP; Chung, YT; Hong, MH; Huang, S; Lin, SS; Pang, WW, 1997) |
| "To evaluate five different preoperative anxiolytic regimens in cataract surgery performed under regional anesthesia; to quantify the pain associated with combined peri- and retrobulbar injection (PRBI) of local anesthetic drugs; and to describe a technique of painless eye block." | 5.08 | Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery. ( Berry, RA; Boezaart, AP; Laubscher, JJ; Nell, ML, 1998) |
| "To evaluate the efficacy of continuous administration of 50% nitrous oxide in oxygen for reducing pain during flexible fiberoptic bronchoscopy 32 children aged 3-60 months were randomly assigned to an experimental or a control group." | 5.08 | [Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination]. ( Dupont, D; Garcia, J; Hayem, C; Roure, P, 1998) |
| "This study compared the pain from intradermal infiltration of (1) plain lidocaine, (2) warmed lidocaine, (3) buffered lidocaine, and (4) warmed, buffered lidocaine." | 5.08 | Pain reduction in lidocaine administration through buffering and warming. ( Colaric, KB; Moore, K; Overton, DT, 1998) |
| "We describe a simple, noninvasive technique that significantly lowered perceived pain during the administration of unbuffered lidocaine with epinephrine local anesthetic." | 5.08 | Repetitive pinching of the skin during lidocaine infiltration reduces patient discomfort. ( Fosko, SW; Gibney, MD; Harrison, B, 1998) |
| "Pain on injection is one of the well-known side effects of propofol." | 5.08 | [Pain-free injection of propofol]. ( Ichimiya, T; Kamada, Y; Kobayashi, Y; Kumagai, A; Namiki, A; Seki, S; Tsuchida, H, 1998) |
| "We evaluated the efficacy of the 60% lidocaine tape in alleviating pain associated with intravenous propofol administration in 71 gynecological patients." | 5.08 | [Sixty percent lidocaine tape alleviates pain on injection of propofol after diminishing venipuncture pain]. ( Akatsuka, M; Doi, Y; Inamori, K; Kunimasa, K; Minami, T; Mori, H; Ohnaka, M; Ohtsuka, M; Uda, R, 1998) |
| "We compared the effect of fentanyl and lidocaine on pain during injection of propofol." | 5.08 | [Reduction of pain on injection of propofol: a comparison of fentanyl with lidocaine]. ( Aketa, K; Ichimiya, T; Kobayashi, Y; Naganuma, R; Namiki, A; Seki, S, 1998) |
| "The purpose of the present study is to compare the injection pain of propofol with that of benzodiazepines when used for intravenous sedation." | 5.08 | Pain following intravenous administration of sedative agents: a comparison of propofol with three benzodiazepines. ( Fukuda, K; Ichinohe, T; Kaneko, Y; Kasahara, M; Mamiya, H; Noma, T, 1998) |
| "Use of lidocaine hydrochloride as a diluent for benzathine penicillin G does not change the penicillin concentration in body fluids and significantly reduces the pain of injection." | 5.08 | Lidocaine as a diluent for administration of benzathine penicillin G. ( Amir, J; Cohen, YH; Ginat, S; Keller, N; Marcus, TE; Varsano, I, 1998) |
| " The diphenhydramine median pain score was 55 mm, compared with 12." | 5.08 | Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia. ( Bartfield, JM; Jandreau, SW; Raccio-Robak, N, 1998) |
| "9% sodium chloride containing the preservative benzyl alcohol with lidocaine hydrochloride 1% as an intradermal pretreatment for the relief of pain associated with intravenous cannulation." | 5.08 | Intradermal bacteriostatic 0.9% sodium chloride containing the preservative benzyl alcohol compared with intradermal lidocaine hydrochloride 1% for attenuation of intravenous cannulation pain. ( McNelis, KA, 1998) |
| "To investigate the effects of warming vs buffering, and warming with buffering, on the pain of lidocaine infiltration." | 5.08 | The effects of warming and buffering on pain of infiltration of lidocaine. ( Bartfield, JM; Crisafulli, KM; Raccio-Robak, N; Salluzzo, RF, 1995) |
| "Lignocaine has been shown to reduce the incidence of pain on injection of propofol." | 5.07 | Propofol injection pain: comparing the addition of lignocaine or metoclopramide. ( Mecklem, DW, 1994) |
| "A prospective, randomised, double-masked, placebo-controlled study was carried out on 169 patients undergoing cataract extraction to compare the topical anaesthetic cream amethocaine with EMLA (eutetic mixture of local anaesthetic, lignocaine and prilocaine) and placebo in reducing pain during retrobulbar injection." | 5.07 | A comparison of amethocaine cream with lignocaine-prilocaine cream (EMLA) for reducing pain during retrobulbar injection. ( Joyce, PW; Kirby, J; Sunderraj, P; Villada, J; Watson, A, 1994) |
| "Benzyl alcohol is reported to be painless on injection and to provide limited dermal anesthesia." | 5.07 | Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia. ( Howe, NR; Williams, JM, 1994) |
| "A controlled, double-blind study was performed to compare the prior administration of intravenous saline 4 ml (n = 36), lignocaine 20 mg (n = 36) or thiopentone 100 mg (n = 43) on the pain produced by intravenous injection of propofol." | 5.07 | Pain during injection of propofol. The effect of prior administration of thiopentone. ( Lee, TW; Loewenthal, AE; Strachan, JA; Todd, BD, 1994) |
| "A randomized double-blind study was made of 60 children aged 5 to 11 years to assess the efficacy of a eutectic mixture of local anaesthetics (EMLA), lidocaine and prilocaine, and placebo cream in reducing venepuncture pain." | 5.07 | Placebo effect of eutectic mixture of lidocaine and prilocaine (EMLA) cream in reducing venepuncture pain in children. ( Lurngnateetape, A; Tritrakarn, T, 1994) |
| "5% bupivacaine, and 2% lidocaine for pain of injection and duration of anesthesia." | 5.07 | Pain of injection and duration of anesthesia for intradermal infiltration of lidocaine, bupivacaine, and etidocaine. ( Howe, NR; Williams, JM, 1994) |
| "A controlled randomized double-blinded clinical study was undertaken to evaluate and compare the efficacy of three methods of preventing pain during injection of propofol on induction of anesthesia." | 5.07 | Pain on injection of propofol. ( Chen, GT; Chen, TY; Hwang, MH; Lin, JC; Lin, SS, 1994) |
| "Sixteen men and 25 women with pain in one or more cervical zygapophyseal joints after automobile accidents (mean age, 43 years; median duration of pain, 39 months) were randomly assigned to receive an intraarticular injection of either bupivacaine (0." | 5.07 | Lack of effect of intraarticular corticosteroids for chronic pain in the cervical zygapophyseal joints. ( Barnsley, L; Bogduk, N; Lord, SM; Wallis, BJ, 1994) |
| "To compare room-temperature unbuffered lidocaine, warm lidocaine, buffered lidocaine, and warm buffered lidocaine to determine which of the four solutions is least painful during infiltration." | 5.07 | Reducing the pain of local anesthetic infiltration: warming and buffering have a synergistic effect. ( Garb, JL; Mader, TJ; Playe, SJ, 1994) |
| "To compare the pain associated with ceftriaxone sodium injections by using two different diluents, ie, lidocaine hydrochloride and sterile water." | 5.07 | Lidocaine as a diluent for ceftriaxone in the treatment of gonorrhea. Does it reduce the pain of the injection? ( Bernstein, B; Fitzgerald, J; Schechter, N; Schichor, A; Weinerman, H; Yordan, E, 1994) |
| "To determine whether use of lidocaine-prilocaine 5% cream (EMLA) decreases pain associated with diphtheria-pertussis-tetanus (DPT) vaccination in infants." | 5.07 | Use of lidocaine-prilocaine cream for vaccination pain in infants. ( Goldbach, M; Ipp, M; Koren, G; Nulman, I; Taddio, A, 1994) |
| "In this study of 24 adult volunteers, diphenhydramine 1% was as effective as lidocaine 1% for achieving dermal local anesthesia, although injection was more painful." | 5.07 | Validation of diphenhydramine as a dermal local anesthetic. ( Gorchynski, J; Green, SM; Rothrock, SG, 1994) |
| "Our previous study demonstrated that 1% diphenhydramine is as effective as 1% lidocaine for anesthesia in minor laceration repair, but that it also is more painful to inject." | 5.07 | 1% lidocaine versus 0.5% diphenhydramine for local anesthesia in minor laceration repair. ( Ernst, AA; Mall, G; Marvez-Valls, E; Patterson, J; Weiss, SJ; Xie, X, 1994) |
| "Eleven homosexual men were studied to evaluate the efficacy and pain associated with intralesional vinblastine with or without 1% bicarbonate buffered lidocaine (BBL)." | 5.07 | Intralesional vinblastine for cutaneous Kaposi's sarcoma associated with acquired immunodeficiency syndrome. A clinical trial to evaluate efficacy and discomfort associated with infection. ( Bason, MM; Berger, TG; Boudreaux, AA; Cosby, CD; Smith, LL; Tappero, JW, 1993) |
| "To test whether buffered lidocaine is less painful to administer as a digital nerve block than plain lidocaine." | 5.07 | Buffered versus plain lidocaine for digital nerve blocks. ( Bartfield, JM; Ford, DT; Homer, PJ, 1993) |
| "To compare the degree of pain of intradermal infiltration and the duration of anesthesia for 1% lidocaine with epinephrine 1:100,000, 1% lidocaine with epinephrine 1:100,000 with 80 meq/L sodium bicarbonate, bacteriostatic saline solution with 1% lidocaine with epinephrine 1:300,000, and bacteriostatic saline solution with 1% lidocaine with epinephrine 1:100,000." | 5.07 | Less painful alternatives for local anesthesia. ( Lugo-Janer, G; Padial, M; Sánchez, JL, 1993) |
| "A double-blind study was set up to investigate the effect of pretreatment with lignocaine on the incidence of potassium chloride infusion pain." | 5.07 | Efficacy of lignocaine in alleviating potassium chloride infusion pain. ( Khoo, ST; Kloo, ST; Lim, ET; Tweed, WA, 1992) |
| "We have conducted a randomized, double-blind study in 255 ASA I and II patients to compare the efficacy of lignocaine and metoclopramide in minimizing the pain of injection of i." | 5.07 | Pain on injection of propofol: comparison of lignocaine with metoclopramide. ( Fee, JP; Ganta, R, 1992) |
| "The emulsion of lidocaine and prilocaine (EMLA) is effective in preventing the pain of venipuncture in children." | 5.07 | Pain perception and effectiveness of the eutectic mixture of local anesthetics in children undergoing venipuncture. ( Blanchette, V; Eliopoulos, C; Greenberg, M; Hwang, P; Klein, N; Koren, G; Olivieri, N; Robieux, I, 1992) |
| "kg-1 on reducing injection pain caused by propofol was compared with lignocaine 10 mg mixed with propofol (Lign)." | 5.07 | Injection pain, cardiovascular changes and recovery following induction of anaesthesia with propofol in combination with alfentanil or lignocaine in children. ( Hiller, A; Saarnivaara, L, 1992) |
| "The clinical benefits of transdermal 10% lidocaine base gels with and without 3% glycyrrhetinic acid monohemiphthalate disodium (GAMHPh) for reduction of pain at venous cannulation were compared in a randomized, double-blind fashion in 24 surgical patients." | 5.07 | A comparative study of transdermal 10% lidocaine gel with and without glycyrrhetinic acid monohemiphthalate disodium for pain reduction at venous cannulation. ( Hashiguchi, A; Kano, T; Mishima, M; Morioka, T; Nakamura, M; Nakano, M, 1992) |
| "In a single-blind study of 100 children aged 1 to 10 years, the minimum effective dose of lignocaine required to prevent injection pain due to propofol was 0." | 5.07 | The minimum effective dose of lignocaine to prevent injection pain due to propofol in children. ( Cameron, E; Crofts, S; Johnston, G; Morton, NS, 1992) |
| "In a double blind study, 21 patients with chronic spinal cord injury (SCI) pain underwent placement of a lumbar subarachnoid catheter and injection of placebo and lidocaine." | 5.07 | Diagnostic spinal anaesthesia in chronic spinal cord injury pain. ( Donovan, WH; Loubser, PG, 1991) |
| "Propofol has a high incidence of pain with injection, particularly into small veins." | 5.07 | Lidocaine for the prevention of pain due to injection of propofol. ( Davis, FM; King, SY; Murchison, DJ; Pryor, PJ; Wells, JE, 1992) |
| "We evaluated the efficacy of intravenous lidocaine, with and without a tourniquet, to decrease the intensity of pain during intravenous propofol injection in 82 patients undergoing general anesthesia." | 5.07 | Tourniquet at 50 mm Hg followed by intravenous lidocaine diminishes hand pain associated with propofol injection. ( Holak, EJ; Mangar, D, 1992) |
| "EMLA cream (Astra Pharmaceuticals) which contains lignocaine and prilocaine, is widely used in a thick layer to reduce the pain associated with venepuncture." | 5.07 | Thickly and thinly applied lignocaine-prilocaine cream prior to venepuncture in children. ( Sims, C, 1991) |
| "A single-blind, randomised, controlled study was undertaken to compare the efficacy of three methods of preventing pain during injection of propofol on induction of anaesthesia." | 5.07 | Effect of prior administration of cold saline on pain during propofol injection. A comparison with cold propofol and propofol with lignocaine. ( Barker, P; Langton, JA; Murphy, P; Rowbotham, DJ, 1991) |
| "Pain on injection of propofol was assessed in a controlled, randomised study of 273 patients." | 5.07 | Modification of pain on injection of propofol--a comparison between lignocaine and procaine. ( A'Hern, RP; Edwards, J; Moriarty, J; Nicol, ME; Robbie, DS, 1991) |
| "A randomised, placebo controlled, double-masked study was undertaken in 115 patients undergoing cataract surgery to assess the efficacy of the anaesthetic cream EMLA (eutetic mixture of local anaesthetic, lignocaine-prilocaine) in alleviating the pain of retrobulbar injection." | 5.07 | A double-masked evaluation of lignocaine-prilocaine cream (EMLA) used to alleviate the pain of retrobulbar injection. ( Joyce, PW; Kirby, J; Sunderraj, P; Watson, A, 1991) |
| "The purpose of this study was to define the optimum dose of lignocaine required to reduce pain on injection of propofol." | 5.07 | Optimal dose of lignocaine for preventing pain on injection of propofol. ( Gehan, G; Karoubi, P; Leroy, A; Pourriat, JL; Quinet, F; Rathat, C, 1991) |
| "Previous reports have suggested that pain associated with the injection of lidocaine is related to the acidic pH of the solution." | 5.07 | Reduction in injection pain using buffered lidocaine as a local anesthetic before cardiac catheterization. ( Dehmer, GJ; Petrozzi, R; Sapin, P, 1991) |
| "A topical anesthetic emulsion consisting of a mixture of lidocaine and prilocaine (EMLA) was used in an attempt to reduce the pain associated with radial artery cannulation." | 5.06 | Local anesthesia for radial artery cannulation: a comparison of a lidocaine-prilocaine emulsion and lidocaine infiltration. ( Desmond, MJ; Fox, MA; Russell, GN, 1988) |
| "A quantitative comparison was made of the effect of infiltration of local analgesics and topical analgesic cream (EMLA) on laser-induced pain and histamine-induced wheal, flare and itch." | 5.06 | A quantitative comparison of the effect of local analgesics on argon laser induced cutaneous pain and on histamine induced wheal, flare and itch. ( Arendt-Nielsen, L; Bjerring, P, 1990) |
| "The incidence of tourniquet pain was evaluated in two groups of patients with 20 each undergoing orthopedic surgery of the lower extremities during epidural anesthesia using plain solution of either 2% lidocaine or 0." | 5.06 | [The effect of epidural anesthesia on tourniquet pain: a comparison of 2% lidocaine and 0.5% bupivacaine]. ( Lai, KB; Lee, Y; Pan, PM; Tung, MC; Wei, TT; Who, LH; Wong, KL; Wu, KH, 1990) |
| "A prospective study with 161 patients was performed to investigate the effects of intravenous local anaesthetics on the pain of injection following etomidate injection." | 5.06 | [The modification of injection pain and the incidence of thrombophlebitis following etomidate]. ( Maier, C; Rühmann, I, 1990) |
| "A controlled randomised double-blind design was used to study the effect of lignocaine on the pain produced by intravenous injection of propofol." | 5.06 | Pain on injection of propofol. Methods of alleviation. ( Chadwick, S; Harper, NJ; Johnson, RA; Vohra, A, 1990) |
| "One hundred and twenty unpremedicated patients undergoing gynaecological surgery were randomly allocated to one of three equal treatment groups to assess the effectiveness of ethyl chloride in producing instant skin anaesthesia to prevent the pain of venepuncture from a 20 G cannula." | 5.06 | Ethyl chloride and venepuncture pain: a comparison with intradermal lidocaine. ( Armstrong, P; McKeown, D; Young, C, 1990) |
| "The aim of the study was to evaluate the effect of a lidocaine-prilocaine cream (EMLA cream, Astra) in relieving pain during arterial cannulation." | 5.06 | EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream. ( Danielson, K; Engberg, G; Henneberg, S; Nilsson, A, 1990) |
| "Analysis of pooled data and paired data (using patients as their own controls) revealed that infiltrating buffered lidocaine was significantly less painful than plain lidocaine (P = ." | 5.06 | Buffered versus plain lidocaine as a local anesthetic for simple laceration repair. ( Barbera, J; Bartfield, JM; Breuer, B; Gallagher, EJ; Gennis, P, 1990) |
| "The local analgesic efficacy of EMLA Cream (a eutectic mixture of lidocaine and prilocaine; Astra Pharmaceuticals, Sweden) in reducing the pain at Venous cannulation was investigated in a randommized blind study in 75 children scheduled for elective surgery." | 5.06 | Our experience with EMLA Cream (for painless venous cannulation in children). ( Johl, KS; Wig, J, 1990) |
| "A double-masked, randomized clinical trial was conducted to determine if subcutaneous eyelid injections of a bicarbonate-buffered lidocaine-epinephrine-hyaluronidase mixture were less painful than unbuffered injections." | 5.06 | Bicarbonate-buffered lidocaine-epinephrine-hyaluronidase for eyelid anesthesia. ( Eccarius, SG; Gordon, ME; Parelman, JJ, 1990) |
| "In a double-blind controlled design, 7 patients with painful diabetic neuropathy received lidocaine 5 mg/kg or saline intravenously over a period of 30 min." | 5.06 | The effect of intravenous lidocaine on nociceptive processing in diabetic neuropathy. ( Bach, FW; Dejgård, A; Jensen, TS; Kastrup, J; Stigsby, B, 1990) |
| "The prophylactic use of lidocaine in the patient with cardiac chest pain has been reported to reduce the incidence of sudden death from ventricular dysrhythmias in the hospital setting, but few studies have been done in the early prehospital phase." | 5.06 | Prophylactic lidocaine in the prehospital patient with chest pain of suspected cardiac origin. ( Aprahamian, C; Darin, J; Hargarten, KM; Mateer, JR; Stueven, HA; Thompson, BM, 1986) |
| "Both regional intravenous guanethidine and reserpine have been reported as effective in the treatment of reflex sympathetic dystrophy." | 5.06 | A comparison of regional intravenous guanethidine and reserpine in reflex sympathetic dystrophy. A controlled, randomized, double-blind crossover study. ( Gallo, JP; Kaul, AF; Lief, PA; Reisman, RM; Rocco, AG, 1989) |
| "The efficacy of lignocaine (1%) mixed with propofol in reducing pain on injection with propofol was studied in 40 children undergoing elective surgery in a double-blind, randomized comparison with glucose (5%)." | 5.06 | Propofol as an induction agent in children: pain on injection and pharmacokinetics. ( Iisalo, E; Kanto, J; Rosenberg, P; Valtonen, M, 1989) |
| "A new topical anesthetic ointment (EMLA, "eutectic mixture of prilocaine and lidocaine was studied in a double-blind, placebo-controlled trial to evaluate its efficiency in alleviating pain associated with venous, subcutaneous drug reservoir and lumbar punctures in children." | 5.06 | Topical skin anesthesia for venous, subcutaneous drug reservoir and lumbar punctures in children. ( Attias, D; Greenberg, ML; Halperin, DL; Koren, G; Pellegrini, E; Wyss, M, 1989) |
| "The cold and warmth thresholds to thermode stimulation and the sensory and pain thresholds to argon laser stimulation were determined before and after topical application of EMLA (Eutectic Mixture of Local Anaesthetics) cream." | 5.06 | The effect of topically applied anaesthetics (EMLA cream) on thresholds to thermode and argon laser stimulation. ( Arendt-Nielsen, L; Bjerring, P, 1989) |
| "The effects of pH buffering on the pain of administration and efficacy of three local anesthetics (1% lidocaine, 1% lidocaine with 1:100,000 epinephrine, and 1% mepivacaine) were investigated in a randomized, prospective, double-blind study of 25 adult volunteers." | 5.06 | Pain reduction in local anesthetic administration through pH buffering. ( Begalla, K; Buchanan, L; Christoph, RA; Schwartz, S, 1988) |
| "Eight modes of administration of propofol were assessed in order to minimise the pain of injection." | 5.06 | Propofol: clinical strategies for preventing the pain of injection. ( Norman, J; Saunders, DA; Scott, RP, 1988) |
| "The effect of triamcinolone subacromial bursa injection versus naproxen therapy was compared in a randomized, double-blind, placebo-controlled study of 100 patients who had painful shoulders." | 5.06 | Randomized, double-blind, placebo-controlled study of the treatment of the painful shoulder. ( Dobrow, R; Neiman, R; Petri, M; Seaman, WE; Whiting-O'Keefe, Q, 1987) |
| "The local analgesic efficacy of a cream formulation of lidocaine and prilocaine (EMLA) in reducing pain at venous cannulation was investigated in children scheduled for elective surgery." | 5.06 | Reduction of pain at venous cannulation in children with a eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication. ( Iisalo, E; Kanto, J; Lindberg, R; Manner, T; Scheinin, M; Viinamäki, O, 1987) |
| "The effect of the topical application of a lignocaine-prilocaine cream (EMLA) on the pain of venous cannulation was tested in a double-blind manner." | 5.06 | Double-blind evaluation of a lignocaine-prilocaine cream (EMLA) in children. Effect on the pain associated with venous cannulation. ( Korpela, R; Maunuksela, EL, 1986) |
| "Twenty-four patients with localized myofascial pain were treated with injections, 11 with 2 ml lidocaine 1% and 13 with 2 ml diclofenac (Voltaren) (50 mg) given in the trigger-point." | 5.06 | Diclofenac versus lidocaine as injection therapy in myofascial pain. ( Frost, A, 1986) |
| "In a randomized double-blind, cross-over study the effect of intravenous lidocaine (5 mg/kg body weight) on the symptoms and signs of painful diabetic neuropathy of more than 6 months duration has been evaluated." | 5.06 | Intravenous lidocaine infusion--a new treatment of chronic painful diabetic neuropathy? ( Angelo, HR; Dejgård, A; Hilsted, J; Kastrup, J; Petersen, P, 1987) |
| "A shortcut review was carried out to establish whether topical lidocaine was effective at reducing pain and improving oral intake in children with painful oral lesions." | 5.05 | BET 2: Does topical lidocaine improve oral intake in children with painful mouth ulcers? ( Daniel, RMD; Jason, SDO; Jeffrey, SJ, 2020) |
| " When compared to lidocaine, the preventive effect was not so excellent as the latter but injection pain induced by prophylactic occurred less." | 5.05 | The efficacy of Antipyretic Analgesics administration intravenously for Preventing Rocuronium-Associated Pain/Withdrawal Response: a systematic review and meta-analysis. ( Chen, J; Cui, Y; Liu, B; Wang, J, 2020) |
| "Between 2008 and 2016, 16 women presented with constant genital pain that was partly or fully extinguishable with topical vestibular lidocaine, and their pain slowly responded to prolonged vestibule-directed estradiol therapy." | 5.05 | Severe Postmenopausal Genital Pain Treated Successfully With Prolonged Estrogen Therapy: A Case Series and Narrative Review. ( Goetsch, MF, 2020) |
| "The aim of this study was to systematically review the effects of lidocaine mixed with epinephrine and bicarbonate in plastic surgery in terms of onset, duration, and the pain score." | 5.05 | Onset, Duration, and Pain Score Obtained Using Lidocaine Mixed With Epinephrine and Bicarbonate in Plastic Surgery. ( Hwang, K; Kim, H, 2020) |
| "A double-blind, randomised controlled trial was performed to compare the pain experienced on intradermal and subcutaneous injection of lignocaine 1% with adrenaline 1:100,000, lignocaine 1%, procaine 1% and normal saline." | 5.05 | A controlled trial of pain on skin infiltration with local anaesthetics. ( Morris, RW; Whish, DK, 1984) |
| " A randomised double-blind study was performed to determine the efficacy of lidocaine in reducing pain and discomfort associated with venography." | 5.05 | Lidocaine and the reduction of post-venographic pain. ( Gent, M; Hirsh, J; Hull, RD; McLaughlin, D; Ockelford, PA; Powers, PJ; Strasberg, Z, 1984) |
| "A new topical anaesthetic formulation, EMLA, consisting of a eutectic mixture of the two local anaesthetics, prilocaine and lidocaine, was used in an attempt to reduce the pain associated with venous cannulation in children." | 5.05 | EMLA--a eutectic mixture of local anaesthetics for topical anaesthesia. ( Ehrenström Reiz, GM; Reiz, SL, 1982) |
| "In a study including a total of 175 children, ranging in age from 3 months to 3 years and suffering from otitis media, the analgesic effect of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol) syrup was compared with that of lidocaine 0." | 5.05 | Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. ( Michos, N; Stocker, H; Weippl, G, 1985) |
| "A 5% lidocaine-prilocaine local anaesthetic cream, EMLA (Eutectic Mixture of Local Anaesthetics), has proved to be an effective remedy for alleviation of venipuncture pain when applied to intact skin for 60 min." | 5.05 | [Pain relief in vein puncture. Application time and effectiveness of lidocaine-prilocaine-cream]. ( Dohlwitz, A; Uppfeldt, A, 1985) |
| "We studied 41 consecutive patients receiving intravenous (IV) diazepam in the preoperative holding area to evaluate whether low-dose IV lidocaine could ameliorate pain of the diazepam injection." | 5.05 | Lidocaine reduces intravenous diazepam pain. ( Ampel, L; Herr, RD; Natonson, R, 1985) |
| "Intra-arterial lidocaine has been utilized to decrease pain by administration prior to contrast material injections during aortofemoral arteriography in over 600 patients." | 5.04 | The use of intra-arterial lidocaine to control pain due to aortofemoral arteriography. ( Robbins, AH; Singer, RJ; Widrich, WC, 1977) |
| "It has been shown that lidocaine administered as a bolus intra-arterially immediately prior to contrast media injections significantly decreased the pain experienced from aortofemoral arteriography." | 5.04 | Adjuvant intra-arterial lidocaine in aortofemoral arteriography: some further observations. ( Goldstein, SA; Robbins, AH; Singer, RJ; Widrich, WC, 1978) |
| " This painful condition, occurring during the immediate postoperative period, is termed transient neurological symptoms (TNS) and is typically observed after the use of spinal lidocaine." | 5.01 | Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta-analysis. ( Borovac, JA; Forget, P; Pace, NL; Thackeray, EM, 2019) |
| "Current approaches to pain management now include (1) new uses of old drugs such as ketamine and lidocaine, (2) use of new drugs/medications such as cannabinoids, and (3) creative use of old technology such as atomizers, intranasal drops, and inhalation." | 5.01 | Novel Approaches for Treating Pain in Children. ( Splinter, W, 2019) |
| "Lidocaine spray was the most effective medication for reducing pain during OEB (P-score = 0." | 5.01 | Medications for pain relief in outpatient endometrial sampling or biopsy: a systematic review and network meta-analysis. ( Abbas, AM; Abdallah, KM; Abdelbaky, WH; Ahmed, MAM; Badawy, MA; El-Naser Abd El-Gaber Ali, A; El-Rasheedy, MI; Elktatny, HH; Khodry, MM; Mohammed, AE; Raslan, OK; Samy, A, 2019) |
| "This meta-analysis suggests that applying lidocaine before NG tube insertion can alleviate pain and discomfort by 26% without increasing nasal bleeding or vomiting." | 4.98 | The application of lidocaine to alleviate the discomfort of nasogastric tube insertion: A systematic review and meta-analysis. ( Chao, HC; Chen, HH; Hsu, YF; Hwang, LC; Liu, SJ; Lor, YC; Shih, PC; Yeh, TL, 2018) |
| " The incorporation of lidocaine with HA provides a pain-relieving alternative for individuals considering facial rejuvenation." | 4.98 | Effectiveness and Safety of Hyaluronic Acid Gel with Lidocaine for the Treatment of Nasolabial Folds: A Systematic Review and Meta-analysis. ( Luan, J; Luan, S; Mi, B; Panayi, AC; Wang, C; Xin, M, 2018) |
| "Systematic review and meta-analysis to assess the effects of uterine or paracervical lidocaine application on pain control during IUD insertion." | 4.98 | Uterine or paracervical lidocaine application for pain control during intrauterine contraceptive device insertion: a meta-analysis of randomised controlled trials. ( Hernandez, AV; Martinez-Dominguez, SJ; Perez-Lopez, FR; Perez-Roncero, GR, 2018) |
| "To evaluate the effect and safety of 5-hydroxytryptamine (5-HT) receptor antagonist in alleviating the pain of patients under general anesthesia induced by rocuronium injection and preemptive analgesia." | 4.98 | The Effect of 5-Hydroxytryptamine Receptor Antagonist in Preventing Pain/Limb Shrinkage Reaction Associated with Rocuronium Injection. ( He, Q; Zhou, C; Zhu, Y, 2018) |
| "Pain on injection of lidocaine is often considered a necessary evil, but it can be reduced by simple means." | 4.95 | Reduced pain when injecting lidocaine. ( Finsen, V, 2017) |
| " All randomized controlled trials that using lidocaine for propofol injection pain in children were enrolled." | 4.95 | Efficacy of lidocaine on preventing incidence and severity of pain associated with propofol using in pediatric patients: A PRISMA-compliant meta-analysis of randomized controlled trials. ( Fu, YZ; Lang, BC; Yang, CS; Zhang, LL; Zhang, WS, 2017) |
| "The objectives of this review were to assess the ability of both pharmacological and non-pharmacological interventions to reduce or eliminate the pain that accompanies rocuronium bromide administration." | 4.93 | Pharmacological and non-pharmacological interventions for reducing rocuronium bromide induced pain on injection in children and adults. ( Ali, Z; Kalaivani, M; Prabhakar, H; Singh, GP; Smith, MA, 2016) |
| "The objective of this review was to determine the efficacy and adverse effects of lidocaine in preventing high-intensity pain on propofol injection." | 4.93 | Lidocaine for reducing propofol-induced pain on induction of anaesthesia in adults. ( Dej-Arkom, S; Euasobhon, P; Lumbiganon, P; Muangman, S; Pattanittum, P; Siriussawakul, A; Sriraj, W, 2016) |
| "Bupivacaine was found to have better promotion to pain control than did lidocaine for the patients after nasal surgery." | 4.93 | Efficacy and safety of bupivacaine versus lidocaine in local anesthesia of the nasopharynx: A meta-analysis. ( He, Z; Huang, L; Wang, J; Yu, X, 2016) |
| " Lidocaine 2% gel, misoprostol, and most NSAIDs did not help reduce pain." | 4.91 | Interventions for pain with intrauterine device insertion. ( Allen, RH; Bartz, D; Bernholc, A; Hubacher, D; Lopez, LM; O'Brien, PA; Zeng, Y, 2015) |
| " Among the products used, and with respect to their mode of delivery, only paracervical lidocaine was effective in producing lower VAS pain scores related to tenaculum placement (mean difference [MD]: - 20." | 4.90 | Analgesic options for placement of an intrauterine contraceptive: a meta-analysis. ( Pergialiotis, V; Protopappas, A; Vlachos, DG; Vlachos, GD, 2014) |
| "68) indicating lidocaine was more effective than BaNS in providing pain relief (P < ." | 4.90 | Intradermal lidocaine or bacteriostatic normal saline to decrease pain before intravenous catheter insertion: a meta-analysis. ( Cook, P; Fink, R; Hoffecker, L; Kleiner, C; Makic, MB; Mancuso, M; Oman, KS; Schmiege, S; Wenger, B, 2014) |
| " The one small randomised double-blind placebo-controlled cross-over trial found in 2012, which included only 45 participants and compared intravenous lidocaine against placebo as a means of pain relief in people with burns still remains central to this review." | 4.90 | Intravenous lidocaine for the treatment of background or procedural burn pain. ( Cleland, H; Danilla, S; Mahar, PD; McGuinness, SK; Spinks, A; Tan, HB; Wasiak, J, 2014) |
| "This update identified one new randomised, double-blind, placebo-controlled, cross-over trial which included 45 participants and compared intravenous lidocaine against placebo as a means of pain relief in those with burns." | 4.88 | Intravenous lidocaine for the treatment of background or procedural burn pain. ( Cleland, H; Danilla, S; Mahar, P; McGuinness, SK; Spinks, A; Wasiak, J, 2012) |
| "Two trials (470 participants with venous leg ulcers) evaluated ibuprofen slow-release foam dressings for persistent venous leg ulcer pain." | 4.88 | Topical agents or dressings for pain in venous leg ulcers. ( Briggs, M; Martyn-St James, M; Nelson, EA, 2012) |
| "There is no evidence that ibuprofen dressings offer pain relief, as measured at the first evening of use, to people with painful venous leg ulcers compared with foam dressings or best practice." | 4.86 | Topical agents or dressings for pain in venous leg ulcers. ( Briggs, M; Nelson, EA, 2010) |
| "Lidocaine administration produces pain due to its acidic pH." | 4.86 | Adjusting the pH of lidocaine for reducing pain on injection. ( Arora Gandhi, P; Cepeda, MS; Hudcova, J; Schumann, R; Thackrey, M; Tzortzopoulou, A, 2010) |
| "We reviewed previous reports cited in PubMed, Biosis and the Cochrane Library, identified by a professional librarian searching for English language-only randomized controlled studies involving the keywords, lidocaine, cystoscopy, gel and pain, yielding 14 studies." | 4.85 | Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief? ( Aaronson, DS; Davies, BJ; Hsieh, MH; Konety, BR; Smith, JF; Walsh, TJ, 2009) |
| " Symptoms, interventions, and treatment-related adverse events addressed in this issue are management of Alzheimer's agitation with donepezil; needle-free lidocaine powder for minor painful procedures; psychostimulants in depression; anticoagulation for cancer-related venous thromboembolism; effect of waiting for acute pain treatment on risk of chronic pain; and an update on severe cutaneous reactions associated with medications." | 4.85 | Pain and palliative care pharmacotherapy literature summaries and analyses. ( Abernethy, AP; Farrell, TW, 2009) |
| "All RCTs and quasi-RCTs reporting use of cyclobenzaprine for treating MP with pain assessment as a primary or secondary outcome." | 4.85 | Cyclobenzaprine for the treatment of myofascial pain in adults. ( Andriolo, RB; Atallah, AN; da Silva, EM; El Dib, R; Grossmann, E; Januzzi, E; Leite, FM, 2009) |
| " This update will review safety, techniques, pain reduction by mixing with lidocaine and the use of CaHA in ethnic skin." | 4.85 | Calcium hydroxylapatite (Radiesse): safety, techniques and pain reduction. ( Busso, M, 2009) |
| "Lidocaine is a use-dependent sodium channel blocker that produces analgesia when administered intravenously to patients with neuropathic pain." | 4.84 | Intravenous lidocaine for neuropathic pain: diagnostic utility and therapeutic efficacy. ( Carroll, I, 2007) |
| "A reasonable body of evidence, along with extensive clinical experience, suggests that intravenous lidocaine can have a useful pain-relieving effect and is worth consideration in palliative care patients." | 4.84 | Intravenous lidocaine: an outdated or underutilized treatment for pain? ( McCleane, G, 2007) |
| "To assess the safety and effectiveness of intravenous lidocaine as a means of pain relief versus no therapy, placebo, other drugs or two or more of the above therapies in combination in patients exposed to burn injury." | 4.84 | Lidocaine for pain relief in burn injured patients. ( Cleland, H; Wasiak, J, 2007) |
| "To review the recommendations and studies related to the use of intradermal lidocaine to decrease pain during arterial punctures." | 4.83 | Use of local anesthesia for arterial punctures. ( Dukes, SF; Hudson, TL; Reilly, K, 2006) |
| " The weighted mean difference in 100-mm visual analogue scale pain scores favored topical tetracaine over EMLA (-8." | 4.82 | Topical anesthetics for dermal instrumentation: a systematic review of randomized, controlled trials. ( Carr, DB; Eidelman, A; Lau, J; Weiss, JM, 2005) |
| "Lidocaine and oral analogs were safe drugs in controlled clinical trials for neuropathic pain, were better than placebo, and were as effective as other analgesics." | 4.82 | Systemic administration of local anesthetic agents to relieve neuropathic pain. ( Carr, DB; Challapalli, V; Lau, J; McNicol, ED; Tremont-Lukats, IW, 2005) |
| "To determine the relative efficacy of lidocaine-prilocaine and tetracaine for procedural pain in children." | 4.81 | Lidocaine-prilocaine cream versus tetracaine gel for procedural pain in children. ( Gurguis, MG; Koren, G; Taddio, A, 2002) |
| "Pain on injection of propofol is a common problem, the cause of which remains unknown." | 4.80 | Pain on injection of propofol. ( Onsiong, MK; Tan, CH, 1998) |
| "The best intervention to prevent pain on injection with propofol is unknown." | 4.80 | Prevention of pain on injection with propofol: a quantitative systematic review. ( Picard, P; Tramèr, MR, 2000) |
| "Although lidocaine alone will serve as an excellent anesthetic for most patients, using less painful injectable agents, topical anesthetics, and occasionally oral sedation will offer the frightened or pain-intolerant patient an acceptable and effective alternative system of local anesthesia." | 4.79 | Choosing a local anesthetic. ( Holmes, HS, 1994) |
| "5% bupivacaine was associated with lower intraoperative and postoperative visual analog scale pain scores." | 4.31 | Wide Awake Local Anesthesia No Tourniquet Technique in Hand Surgery: The Patient Experience. ( Cusano, A; Ferreira, J; LeVasseur, MR; Olivieri-Ortiz, R; Parrino, A; Pina, M, 2023) |
| " Inclusion criteria were documented radial synergy test, Eichoff's test, and ≥90% pain relief after lidocaine/corticosteroid injection." | 4.31 | The Radial Synergy Test: An Aid to Diagnose de Quervain's Tenosynovitis. ( Hogan, CJ; Langford, MA; Langford, PN; Lee, C; Ruland, RT; Sullivan, GE, 2023) |
| "Lidocaine aerosol sprayed on oral and/or nasal mucosa is beneficial for immediate pain relief in patients with acute trigeminal neuralgia exacerbations." | 4.31 | Lidocaine aerosol sprayed on oral and/or nasal mucosa for the rescue of acute trigeminal neuralgia exacerbations: A retrospective study. ( Luo, F; Shen, Y; Zhao, C; Zhou, X, 2023) |
| "When comparing with topical lidocaine/prilocaine (EMLA) cream, a 1:1 mixture of 1% lidocaine and epinephrine significantly alleviated pain during and after the corticosteroid injection." | 4.31 | Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study. ( Park, TH, 2023) |
| "This study showed that GONB with lidocaine can improve sleep quality, insomnia, and symptoms of depression and anxiety while reducing migraine headache." | 4.31 | The effects of greater occipital nerve blockage with lidocaine on sleep characteristics in chronic migraine patients. ( Dilek, SS; İnan, LE; Karaduman, Y; Metin, KM; Serçe, A; Takmaz, SA, 2023) |
| "Achilles tendinosis treatment with paratenon lidocaine hydrodissection and subsequent prolotherapy with hyperosmolar glucose solution is safe, effective, inexpensive, and virtually painless with results maintained over time." | 4.31 | Can Achilles tendinosis be treated effectively with lidocaine and glucose infiltrations, and if so, is the effect lasting? A longitudinal, observational on 27 consecutive patients. ( Bello Baez, A; Cavada Laza, A; Mora Guanche, P; Nieto Morales, ML; Pérez Méndez, LI, 2023) |
| "Based on the potency ratios of clonidine and dexmedetomidine (8 to 1) we hypothesize that a lower dexmedetomidine dose would provide patients with 50 min of pain free tourniquet time." | 4.12 | A sequential allocation study to determine the ED ( Al Assadi, S; Kanazi, G; Karam, C; Zeeni, C, 2022) |
| "To compare the onset, anesthesia depth, and duration of topical 10% lidocaine and EMLA cream." | 4.12 | Comparison of the onset, depth, and duration of cutaneous anesthesia between topical 10% lidocaine and EMLA creams: a randomized, intraindividual, comparative trial. ( Deewongkij, P; Junputipong, N; Kamanamool, N; Rojhirunsakool, S; Udompataikul, M, 2022) |
| "We present a case of a middle-aged woman with no prior history of deep venous thrombosis, with a blue swollen left leg in intractable severe pain unresponsive to 3 doses of hydromorphone." | 4.12 | Phlegmasia cerulea dolens causing compartment syndrome. ( Aydemir, B; Hakmeh, W; Hoyle, C, 2022) |
| "Topical lidocaine patches are commonly used to relieve pain and suffering in various clinical and household settings." | 4.12 | Printed graphene-based electrochemical sensor with integrated paper microfluidics for rapid lidocaine detection in blood. ( Kadian, S; Krishnakumar, A; Mishra, RK; Rahimi, R; Rivera, UH; Zareei, A, 2022) |
| "Lidocaine hydrochloride is frequently used for management of painful wounds." | 4.12 | 5% Lidocaine Hydrochloride Cream for Wound Pain Relief: A Multicentre Observational Study. ( Arnez, ZM; Davini, G; Dini, V; Janowska, A; Oranges, T; Papa, G; Romanelli, M; Stocco, C, 2022) |
| "In patients pretreated with lidocaine, no pain 56 (87." | 4.02 | Lidocaine for Reduction of Pain Induced by Propofol in a Tertiary Care Hospital: A Descriptive Cross-sectional Study. ( Bahadur Chand, M; Ghimire, B, 2021) |
| "To determine the effect of escalating doses of lidocaine infusion with or without added magnesium on pain levels and the duration of pain relief in patients with fibromyalgia (FM)." | 3.96 | Repeated Intravenous Lidocaine Infusions for Patients with Fibromyalgia: Higher Doses of Lidocaine Have a Stronger and Longer-Lasting Effect on Pain Reduction. ( Perelman, VS; Pugacheva, O; Voznyak, Y; Wansbrough, MCT; Wilderman, I; Zolnierczyk, L, 2020) |
| "To evaluate whether administration of lidocaine into the uterine artery for anesthesia immediately after uterine artery embolization (UAE) with trisacryl gelatin microspheres (TAGM) for leiomyoma is safe and effective." | 3.96 | Intra-Arterial Lidocaine Administration for Anesthesia after Uterine Artery Embolization with Trisacryl Gelatin Microspheres for Leiomyoma. ( Asato, A; Katsumori, T; Kotera, Y; Miura, H; Seri, S; Yoshikawa, T, 2020) |
| "To determine the efficacy of lidocaine versus bupivacaine when performing intranasal sphenopalatine ganglion (SPG) block for the treatment of headaches." | 3.96 | Lidocaine Versus Bupivacaine in the Treatment of Headache with Intranasal Sphenopalatine Nerve Block. ( Alli, A; Clark, L; Collins, Z; Fahrbach, T; Kirkpatrick, DL; Lemons, S; Madarang, EJ; Reeves, A; Townsend, T; Walter, C, 2020) |
| "Lidocaine infusion is often used as part of a perioperative, multimodal pain management plan." | 3.96 | Continuous Intravenous Lidocaine Provides Effective Pain Control in a Palliative Child: A Case Report. ( Bell, M; Kim, E; Le, S; Lo, C, 2020) |
| "The purpose of this study was to describe the therapeutic effectiveness/pain relief of moderate-dose lidocaine infusions in patients with chronic neuropathic pain." | 3.91 | Intravenous Lidocaine for Relief of Chronic Neuropathic Pain. ( Albala, MZ; Hudson, A; Lancaster, RJ; Leavitt, K; Margelosky, K; Walesh, M; Wren, K, 2019) |
| "Herein, it was investigated whether a complex of lidocaine with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) would present a better antinociceptive profile in vivo when compared with plain lidocaine in models of orofacial pain." | 3.91 | Comparison of antinociceptive effects of plain lidocaine versus lidocaine complexed with hydroxypropyl-β-cyclodextrin in animal models of acute and persistent orofacial pain. ( Araya, EI; Chichorro, JG; Claudino, RF; de Oliveira, SB; Ferreira, LEN; Franz-Montan, M; Gambeta, E, 2019) |
| " Suturing is usually accompanied by perilesional administration of lidocaine, a local anaesthetic drug that improves pain tolerance." | 3.91 | Stability of a novel Lidocaine, Adrenaline and Tetracaine sterile thermosensitive gel: A ready-to-use formulation. ( Addobbati, R; Barbi, E; Loiacono, S; Maestro, A; Mamolo, MG; Maximova, N; Volpato, C; Zampieri, D; Zanon, D, 2019) |
| "The current study aimed to investigate the effectiveness of a developed sodium alginate and polyvinylpyrrolidone K-25 (PVP K-25) polymeric wafer for the co-delivery of ketorolac and lidocaine to soft tissues for healing and pain control following gingivectomy." | 3.88 | Mucosal co-delivery of ketorolac and lidocaine using polymeric wafers for dental application. ( El-Feky, GS; Farouk Abdulmaguid, R; Kamel, R; Zayed, GM, 2018) |
| "Results were consistent with the hypothesis that needle-free injection of lidocaine is an effective therapy for the management of pain in children between the ages of 3-16 years who receive an IV." | 3.85 | Transformation of the peripheral intravenous catheter placement experience in pediatrics. ( Devgon, P; Kelly, S; Rosen, P; Russell, J, 2017) |
| "A short review was carried out to see if mixing lidocaine with propofol is a safe and effective method in reducing the commonly reported pain at the injection site." | 3.85 | BET 1: Lidocaine with propofol to reduce pain on injection. ( Baombe, JP; Howard, L, 2017) |
| "The aim of the study was investigate the pain palliation effect of 2% dose of lidocaine on the periprostatic nerve block in prostate biopsy patients." | 3.85 | Retrospective evaluation of the effects of periprostatic local anesthesia on recurrent prostate biopsy. ( Akdeniz, E; Akdeniz, S; Bolat, MS; Çınar, Ö; Gümüş, NE; Şahinkaya, N, 2017) |
| "The aim of this study was to compare the pain-relieving effect of intracervical lidocaine gel with that of lidocaine spray or no local anaesthesia in decreasing pain during insertion of the intrauterine contraceptive device (IUCD)." | 3.85 | Lidocaine gel vs lidocaine spray in reducing pain during insertion of the intrauterine contraceptive device. ( Ahmed, A; Dief, O; El-Desouky, ES; Moussa, A; Torky, H, 2017) |
| "To evaluate topical treatment with clobetasol propionate and lidocaine in women with urethral pain syndrome (UPS) in a retrospective pilot study." | 3.83 | Urethral instillations of clobetasol propionate and lidocaine: a promising treatment of urethral pain syndrome. ( Hellberg, D; Lindström, AK; Lindström, BE, 2016) |
| " In this study, we asked whether PSD increases tonic nociception in the formalin test, decreases the antinociceptive effect of morphine administered into the periaqueductal gray matter (PAG), and disrupts endogenous descending pain modulation." | 3.83 | The Pronociceptive Effect of Paradoxical Sleep Deprivation in Rats: Evidence for a Role of Descending Pain Modulation Mechanisms. ( Arase, M; Bertolini, JF; Fischer, L; Lima, MMS; Pontarolla, FM; Tobaldini, G; Tomim, DH, 2016) |
| " In this study, we investigated spontaneous pain and mechanical allodynia in a preclinical model of oral ulcerative mucositis after systemic administration of the chemotherapy drug 5-fluorouracil, using our proprietary pain assay system for conscious rats." | 3.83 | Distinct TRPV1- and TRPA1-based mechanisms underlying enhancement of oral ulcerative mucositis-induced pain by 5-fluorouracil. ( Goto, T; Harano, N; Hitomi, S; Inenaga, K; Inoue, H; Ito, M; Matoba, M; Miyano, K; Nodai, T; Ono, K; Uezono, Y; Watanabe, S; Yamaguchi, K, 2016) |
| "The analgesic effects on pain-related behaviors following the topical application of hangeshashinto were evaluated in an oral ulcer rat model treated with acetic acid using recently developed methods." | 3.83 | The traditional Japanese medicine hangeshashinto alleviates oral ulcer-induced pain in a rat model. ( Hattori, T; Hitomi, S; Imai, R; Inenaga, K; Kase, Y; Kubota, K; Omiya, Y; Ono, K; Terawaki, K; Yamaguchi, K, 2016) |
| "The aim of this study was to determine whether systemic administration of QX-314 reduces bone cancer pain through selective inhibition of transient receptor potential vanilloid subfamily 1 (TRPV1)-expressing afferents." | 3.83 | Systemic QX-314 Reduces Bone Cancer Pain through Selective Inhibition of Transient Receptor Potential Vanilloid Subfamily 1-expressing Primary Afferents in Mice. ( Fuseya, S; Kawamata, M; Kawamata, T; Minemura, H; Yamamoto, K; Yamaori, S, 2016) |
| " Patients received one of two local anaesthetics (lidocaine injection or lidocaine spray) or no anaesthesia before intratympanic injection, and used a visual analogue scale to indicate the pain level after 5 and 45 minutes." | 3.83 | Effects of two different local anaesthetic methods vs no anaesthesia on pain scores for intratympanic injections. ( Ata, N; Erdur, O; Görgülü, MH; Yilmaz, E, 2016) |
| "This study was designed to evaluate the efficacy and safety of CT-guided embolization of internal iliac artery aneurysm (IIAA) after repair of abdominal aortic aneurysm by transretroperitoneal approach using the lidocaine injection technique to iliacus muscle, making window for safe needle path for three patients for whom CT-guided embolization of IIAA was performed by transretroperitoneal approach with intramuscular lidocaine injection technique." | 3.81 | Transretroperitoneal CT-guided embolization of growing internal iliac artery aneurysm after repair of abdominal aortic aneurysm: a transretroperitoneal approach with intramuscular lidocaine injection technique. ( Choi, SJ; Chung, SY; Kim, HO; Kim, JK; Kim, SJ; Kim, YT; Lee, HK; Lim, NY; Park, JY, 2015) |
| "A single perisciatic injection of lidocaine (2%) produced relief of paw-pinch-evoked pain that was significantly different from baseline through to the 1-hour timepoint (Dunnett multiplicity-adjusted P = 0." | 3.81 | EN3427: a novel cationic aminoindane with long-acting local anesthetic properties. ( Banerjee, M; Baranwal, A; Priestley, T; Saha, A; Saha, S, 2015) |
| "The needle-free jet injection system with buffered lidocaine (J tip) has been shown to reduce pain for intravenous (IV) line insertion, but its relationship with successful IV placement has not been well studied." | 3.81 | The use of the needle-free jet injection system with buffered lidocaine device does not change intravenous placement success in children in the emergency department. ( Brousseau, DC; Drendel, AL; Lunoe, MM, 2015) |
| "We investigated the analgesic effects of lidocaine (LDC) and lidocane derivative, QX-572, co-application on the evoked pain behaviour (complete Freund's Adjuvant (CFA)-induced) and spontaneous pain behaviour (formalin-induced) in mice." | 3.81 | Co-application of lidocaine and QX-572 induces divergent pain behaviours in mice. ( Gao, Y; Jin, D; Shao, CJ; Wang, D; Wang, DQ; Zhao, L, 2015) |
| " We report a case in which a patient presenting with chemotherapy-induced peripheral neuropathy received an IV lidocaine infusion over the course of 60 minutes with complete symptomatic pain relief for a prolonged period of 2 weeks." | 3.81 | Intravenous Lidocaine Infusion to Treat Chemotherapy-Induced Peripheral Neuropathy. ( Chakrabortty, S; Kumar, AJ; Muppuri, R; Papapetrou, P, 2015) |
| " Facilitation of pain behaviour induced by GAL in the DMH was reversed by lidocaine in the DRt and by ondansetron, a 5HT3R antagonist, in the spinal cord." | 3.81 | Galanin-Mediated Behavioural Hyperalgesia from the Dorsomedial Nucleus of the Hypothalamus Involves Two Independent Descending Pronociceptive Pathways. ( Almeida, A; Amorim, D; Pertovaara, A; Pinto-Ribeiro, F; Viisanen, H; Wei, H, 2015) |
| "To compare the use of lubricant gel with lidocaine versus lubricant gel without anesthetic in flexible cystoscopy in terms of pain and tolerability." | 3.81 | Use of Lidocaine 2% Gel Does Not Reduce Pain during Flexible Cystoscopy and Is Not Cost-Effective. ( Arrabal-Martin, M; Arrabal-Polo, MA; Cano-Garcia, Mdel C; Casares-Perez, R; Merino-Salas, S, 2015) |
| "We investigated the effect of a possible interaction between topical analgesic treatment and treatment expectation on pain at the behavioral and neuronal level by combining topical lidocaine/prilocaine treatment with an expectancy manipulation in a 2 by 2 within-subject design (open treatment, hidden treatment, placebo, control)." | 3.80 | Expectation requires treatment to boost pain relief: an fMRI study. ( Büchel, C; Geuter, S; Schenk, LA; Sprenger, C, 2014) |
| "To compare retrospective use of oral sucrose (SUC) vs oral sucrose plus lidocaine ring block (SUC + RB) in the management of pain during neonatal circumcision." | 3.80 | Pre-emptive penile ring block with sucrose analgesia reduces pain response to neonatal circumcision. ( Fogel, J; Hsu, CD; Roman-Rodriguez, CF; Sherlock, DJ; Toussaint, T, 2014) |
| "5% lidocaine medicated plasters are a topical option in the treatment of peripheral neuropathic pain, as monotherapy or as an adjunct to systemic medication." | 3.80 | Use of 5% lidocaine medicated plasters for the treatment of pain in routine hospital practice: patient reported pain, functioning and satisfaction. ( Kadambande, S; Khot, S; Morgan, CL; Poole, CD, 2014) |
| "2 pg/mL), possibly because the sample was collected after the lidocaine ring block was administered, which was likely painful, and because of separation from the dam and restraint." | 3.80 | Healing of surgical castration wounds: a description and an evaluation of flunixin. ( Banuelos, J; Coetzee, JF; Drake, D; Hoar, B; Mintline, EM; Stock, ML; Tucker, CB; Varga, A; Walker, KA; Weary, DM, 2014) |
| "Considering the potential pain and dissatisfaction of rigid cystoscopic ureteral stent removal, procedures utilizing moderate sedation with midazolam or general anesthesia using propofol without muscle relaxation should be considered." | 3.80 | Pain and satisfaction during rigid cystoscopic ureteral stent removal: a preliminary study. ( Cho, SW; Choi, H; Kim, JH; Kim, MG; Park, SY; Song, D; Song, YS, 2014) |
| "The present study was aimed at investigating the analgesic properties of a combination of lidocaine and QX-222 and its effects on evoked pain behavior (complete Freund's adjuvant-induced allodynia and hyperalgesia in inflammatory condition) and spontaneous pain behavior (formalin-induced acute pain) in mice." | 3.80 | Coapplication of lidocaine and membrane-impermeable lidocaine derivative QX-222 produces divergent effects on evoked and spontaneous nociceptive behaviors in mice. ( Chen, C; Gui, JB; Hu, SP; Liu, Y; Wang, WX; Wu, HF; Yu, L; Zhao, JJ, 2014) |
| "This study shows that lidocaine, a peripheral analgesic, significantly altered DMN connectivity and affected its relationship with pain-related networks." | 3.79 | Functional connectivity of the default mode network and its association with pain networks in irritable bowel patients assessed via lidocaine treatment. ( Craggs, JG; Letzen, JE; Perlstein, WM; Price, DD; Robinson, ME, 2013) |
| "8 mL 2% lidocaine with 1:100,000 epinephrine in patients presenting with symptomatic irreversible pulpitis." | 3.79 | Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis? ( Fowler, S; Reader, A, 2013) |
| " Prior to their first injection, subjects rated the pain intensity of a standardized subcutaneous (SQ) injection of lidocaine prior to the full dose." | 3.79 | Does pain score in response to a standardized subcutaneous local anesthetic injection predict epidural steroid injection outcomes in patients with lumbosacral radiculopathy? A prospective correlational study. ( Buckenmaier, CC; Chen, L; Christo, PJ; Cohen, SP; Erdek, MA; Griffith, SR; Gupta, A; Kurihara, C; Mao, J; Strassels, SA; Vu, TN, 2013) |
| " In another experiment, the preparation was tested in a further 22 subjects for its pain-relieving effect during a standard palatal injection, and compared with 18% benzocaine/2% tetracaine gel." | 3.78 | Relief of palatal injection pain by liposome-encapsulated 2% lignocaine prepared by ultrasonic dental scaler. ( Paphangkorakit, J; Priprem, A; Sangsirinakagul, C, 2012) |
| " We analyzed data from 5 open-label clinical trials of lidocaine patch 5% in osteoarthritis knee pain and chronic low back pain that were 2 to 12 weeks in duration." | 3.77 | Treatment satisfaction in osteoarthritis and chronic low back pain: the role of pain, physical and emotional functioning, sleep, and adverse events. ( Dworkin, RH; Galer, BS; Gammaitoni, AR; Gould, E; Jensen, MP; Jones, BA; Xiang, Q, 2011) |
| "To evaluate the use of topical lidocaine gel and glyceryl trinitrate ointment (GTN) vs placebo, in reducing anal pain and discomfort as an adjunct to periprostatic anesthesia because of probe insertion, during the use of transrectal ultrasonography (TRUS) prostate-guided biopsy in young patients." | 3.77 | Comparison between lidocaine and glyceryl trinitrate ointment for perianal-intrarectal local anesthesia before transrectal ultrasonography-guided prostate biopsy: a placebo-controlled trial. ( Gekas, A; Konstantinidis, C; Samarinas, M; Skriapas, K; Xanthis, S, 2011) |
| "We conducted experiments in rats to determine optimal concentrations and ratios of lidocaine and QX-314 that produce the greatest degree and duration of pain-selective block when administered nearby the sciatic nerve: reduction in the response to noxious mechanical (pinch) and to radiant heat stimuli, with minimal disruption in motor function (grip strength)." | 3.77 | Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review. ( Bean, BP; Binshtok, AM; Blasl, F; Roberson, DP; Woolf, CJ, 2011) |
| "One hundred twelve emergency patients with irreversible pulpitis received long buccal nerve block injections using 2% lidocaine with 1:100,000 epinephrine." | 3.77 | Long buccal nerve block injection pain in patients with irreversible pulpitis. ( Beck, M; Drum, M; Reader, A, 2011) |
| " Prior to the procedure, subjects rated anxiety on a numerical rating scale (NRS) from 0 (no anxiety) to 3 (extreme anxiety), and received standardized subcutaneous injections of lidocaine (using 25-G needle to infiltrate 2 cc 1% lidocaine) as local anesthesia." | 3.77 | Judging pain sensitivity with subcutaneous lidocaine injections. ( Hunt, P; Manabat, ER; Pujol, LA; Wang, D, 2011) |
| " In the present study, we examined whether dexmedetomidine and clonidine could inhibit the function of tetrodotoxin-sensitive Na(+) channels, which play important roles in the generation of pain." | 3.77 | Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells. ( Kanai, T; Maruta, T; Nemoto, T; Satoh, S; Tsuneyoshi, I; Wada, A; Yanagita, T, 2011) |
| "The study concludes that lidocaine reduced pain during castration and that meloxicam reduced pain after castration." | 3.77 | Effect of local anaesthesia and/or analgesia on pain responses induced by piglet castration. ( Hansson, M; Johansson, G; Lundeheim, N; Nyman, G, 2011) |
| "Although the benefits of adding lidocaine are recognized in terms of relieving the pain experienced upon injection, it would appear beneficial to establish the impact of lidocaine within the Stylage® range, the only one to incorporate both an anaesthetic (lidocaine) and an antioxidant in the form of mannitol in its crosslinked gel of HA." | 3.77 | Benefits of adding lidocaine to a hyaluronic gel - Stylage® M. ( Gozlan, L; Mole, B, 2011) |
| " We proposed that the introduction of a topical anaesthetic gel (lidocaine, adrenaline, tetracaine - LAT) might help to reduce the number of referrals, by allowing the ED staff to perform the procedures, in combination with nonpharmacological approaches." | 3.76 | Topical anaesthesia in children: reducing the need for specialty referral. ( Mullarkey, C; O'Connor, G, 2010) |
| "We tested whether it is possible to selectively block pain signals in the orofacial area by delivering the permanently charged lidocaine derivative QX-314 into nociceptors via TPRV1 channels." | 3.76 | Selectively targeting pain in the trigeminal system. ( Ahn, DK; Bean, BP; Binshtok, AM; Chung, G; Hwang, SJ; Jung, SJ; Kang, Y; Kim, HY; Kim, JS; Kim, K; Lee, MK; Li, HY; Oh, SB; Park, CK; Woolf, CJ, 2010) |
| "The use of peripheral tramadol to block pain has been advocated." | 3.76 | Effects of local tramadol administration on peripheral glutamate-induced nociceptive behaviour in mice. ( Chung, CC; MacLeod, BA; Ries, CR; Schwarz, SK; Wang, JT; Whitehead, RA, 2010) |
| " Wound pain was assessed using calibrated Von-Frey monofilaments over a 4-h period, pain-related behaviour was assessed over 5 h, wound healing was assessed at 14 and 28 days, and the plasma levels of lignocaine and bupivacaine were determined." | 3.76 | Topical anaesthesia alleviates short-term pain of castration and tail docking in lambs. ( Dickson, H; Lomax, S; Sheil, M; Windsor, PA, 2010) |
| "The amount of pain reduction after injection of lidocaine into the subacromial space preoperatively correlates with the level of pain reduction after rotator cuff repair." | 3.76 | Modified impingement test can predict the level of pain reduction after rotator cuff repair. ( Gong, HS; Kim, KH; Kim, SH; Oh, CH; Oh, JH, 2010) |
| "Lidocaine can alleviate acute as well as chronic neuropathic pain at very low plasma concentrations in humans and laboratory animals." | 3.75 | The effect of intravenous lidocaine on brain activation during non-noxious and acute noxious stimulation of the forepaw: a functional magnetic resonance imaging study in the rat. ( Benveniste, H; Du, C; Glass, PS; Kritzer, M; Luo, Z; Ma, Y; Smith, SD; Volkow, ND; Yu, M, 2009) |
| "Pretreatment with 60% lidocaine tape significantly reduces the pain associated with intralesional injection of TA." | 3.75 | Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid. ( Hyakusoku, H; Murakami, M; Tosa, M, 2009) |
| " Whether glycinergic mechanisms, which play a pivotal role in pain modulation, are involved in lidocaine-induced antinociception is hitherto unclear." | 3.75 | Antinociceptive effects of systemic lidocaine: involvement of the spinal glycinergic system. ( Bauer, I; Freynhagen, R; Hermanns, H; Kollosche, K; Lipfert, P; Muth-Selbach, U; Stegmann, JU, 2009) |
| "The use of lidocaine gel intrarectal 2% before a prostate biopsy guided by ultrasound did not diminish the sensation of pain from the procedure in our patients, which was increased by the use of sterilized needles." | 3.75 | [Pain during transrectal ultrasound guided needle biopsy of the prostate: comparison of the use or not of lidocaine gel]. ( Destefano Urrutia, V; Díaz Pérez, GA; Meza Montoya, L; Morante Deza, C; Pow-Sang Godoy, M, 2009) |
| "The intrarectal introduction of lidocaine cream 2% can significantly reduce anal discomfort and pain before the probe insertion for ultrasound guided biopsies in young patients." | 3.75 | Pain level and anal discomfort during transrectal ultrasound for guided prostate biopsy. Does intrarectal administration of local anesthetic before periprostatic anesthesia makes any difference? ( Gekas, A; Kartsaklis, P; Konstandinidis, C; Samarinas, M; Skriapas, K, 2009) |
| "The aim of this study was to establish the effect of lidocaine, a local anesthetic, on pain and itch using formalin-induced nociception and kappa opioid antagonist-induced scratching models in mice." | 3.75 | Inhibitory effect of lidocaine on pain and itch using formalin-induced nociception and 5'-guanidinonaltrindole-induced scratching models in mice: behavioral and neuroanatomical evidence. ( Cowan, A; Dun, NJ; Inan, S, 2009) |
| "The clinical and therapeutical data of a 2 years follow up show that in these 7 cases of chronic benign pain, treated by injecting local anaesthetic (lidocaine 0." | 3.75 | [Our experiences in chronic benign pain by injecting local anaesthetic into scars]. ( Barbagli, P; Bollettin, R, 2009) |
| "The present study investigated the effects of different doses of intrathecal lidocaine on established thermal hyperalgesia and tactile allodynia in the chronic constriction injury model of neuropathic pain, defined the effective drug dose range, the duration of pain-relief effects, and the influence of this treatment on the body and tissues." | 3.75 | Effects of intrathecal lidocaine on hyperalgesia and allodynia following chronic constriction injury in rats. ( Gu, Y; Su, D; Tian, J; Wang, X; Wu, Y, 2009) |
| " In contrast, pain intensity evaluated by the patient tended to be lower in the Entonox group (mean VAS: 2." | 3.74 | [Value of nitrous oxide-oxygen mixture (Entonox) in transrectal prostate biopsies]. ( Dubruille, T; Michel, F; Spie, R; Watfa, J, 2008) |
| "The objective of the present study was to investigate the pain on injection of articaine with adrenaline, prilocaine with phenylpressin , and lidocaine with adrenaline." | 3.74 | A comparison of injection pain with articaine with adrenaline, prilocaine with phenylpressin and lidocaine with adrenaline. ( Celebi, N; Misir, F; Muğlali, M; Sumer, M, 2008) |
| "Some children report significant pain with peripheral intravenous catheter (IV) insertion, despite the appropriate use of topical lidocaine anesthetics." | 3.74 | Predictors of topical anesthetic effectiveness in children. ( Floria-Santos, M; Hanrahan, K; Kleiber, C; McCarthy, AM; Murray, JC; Schutte, DL, 2007) |
| "To assess the efficacy of local infiltrative anesthesia with lidocaine hydrochloride in patients undergoing the surgical repair of a simple vesico-vaginal fistula." | 3.74 | Local anesthesia: an appropriate technology for simple fistula repair. ( Morhason-Bello, IO; Ojengbede, OA, 2007) |
| "The proportion of chronic pain patients with suspected neuropathic pain who will have clinically meaningful pain relief with intravenous (IV) lidocaine and the clinical characteristics that identify these patients have not been described previously." | 3.74 | Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesia. ( Carroll, I; Gaeta, R; Mackey, S, 2007) |
| " We tested the possibility of selectively blocking the excitability of primary sensory nociceptor (pain-sensing) neurons by introducing the charged, membrane-impermeant lidocaine derivative QX-314 through the pore of the noxious-heat-sensitive TRPV1 channel." | 3.74 | Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers. ( Bean, BP; Binshtok, AM; Woolf, CJ, 2007) |
| "To evaluate the efficacy of intramuscular injection of 75 mg diclofenac sodium and periprostatic nerve block (PPNB) with 1% lignocaine in controlling pain during transrectal ultrasound (TRUS)-guided prostate biopsy." | 3.74 | Control of pain during transrectal ultrasound-guided prostate biopsy: a prospective study comparing two methods. ( Bhomi, KK; Consigliere, DT; Lim, HH; Tiong, HY, 2007) |
| "This study assessed patient-perceived pain during phacoemulsification cataract surgery with peribulbar anesthesia (lidocaine 2%-bupivacaine 0." | 3.73 | Pain induced by phacoemulsification without sedation using topical or peribulbar anesthesia. ( Coelho, RP; Romão, E; Velasco e Cruz, AA; Weissheimer, J, 2005) |
| "Of 68 physicians, 46 responded: 98% believed that awake and alert patients find NGT insertion uncomfortable/painful; 93% used measures to reduce this, most commonly lubricant gel, topical anaesthetic spray, lidocaine gel, and distraction/use of a child life worker; 28% believed these provided adequate pain control and 37% believed they were inadequate." | 3.73 | Emergency physicians' practices and attitudes regarding procedural anaesthesia for nasogastric tube insertion. ( Conners, GP; Juhl, GA, 2005) |
| " This case report documents the first death associated with a Botox-lidocaine mixture given to a woman for chronic neck and back pain." | 3.73 | Fatal case of BOTOX-related anaphylaxis? ( Goldberger, BA; Hopkins, C; Li, M, 2005) |
| " Neurovascular bundle blockage with lidocaine is very effective to diminish biopsy associated pain." | 3.73 | [Tolerability and complications of the ultrasound guided transrectal biopsy of the prostate extended to 10 cores. The role of neurovascular bundle blockage with lidocaine]. ( Alonso González, M; Burgos Revilla, FJ; García González, R; Lennie Zucharino, A; Mayayo Dehesa, T; Rodríguez-Patrón Rodríguez, RR, 2005) |
| "To evaluate the intraocular penetration of lidocaine 2% gel after different duration of application and to assess their effects on intraoperative pain." | 3.73 | Effect of application duration of 2% lidocaine jelly on aqueous lidocaine concentration for topical anesthesia in cataract surgery. ( Chu, KO; Kwok, AK; Lai, TY; Lee, VY; Pang, CC; Yeung, YS, 2006) |
| "To compare pain responses in stallions undergoing standing laparoscopic cryptorchidectomy following intratesticular or mesorchial infiltration of lidocaine." | 3.73 | Comparison of intraoperative pain responses following intratesticular or mesorchial injection of lidocaine in standing horses undergoing laparoscopic cryptorchidectomy. ( Hendrickson, DA; Joyce, J, 2006) |
| "Systemic lidocaine and other local anesthetics reduce hypersensitivity states induced by both acute inflammation and peripheral nerve injury in animals and produce analgesia in some patients with chronic pain." | 3.72 | Intrathecal lidocaine reverses tactile allodynia caused by nerve injuries and potentiates the antiallodynic effect of the COX inhibitor ketorolac. ( Du, W; Eisenach, JC; Ma, W, 2003) |
| "Systemic lidocaine can relieve various forms of neuropathic pain that develop after nerve injury." | 3.72 | Multiple phases of relief from experimental mechanical allodynia by systemic lidocaine: responses to early and late infusions. ( Araujo, MC; Sinnott, CJ; Strichartz, GR, 2003) |
| "Amiodarone was found to produce a statistically significant decrease in heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain after intraperitoneal injection." | 3.72 | Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain. ( Datta, S; Glusman, S; Torres, M; Waghray, T, 2004) |
| "We present a case of persistent central pain after encephalitis in a patient who had long-term pain relief after a series of IV lidocaine infusions." | 3.72 | The long-term effect of repeated intravenous lidocaine on central pain and possible correlation in positron emission tomography measurements. ( Annoni, JM; Cahana, A; Carota, A; Montadon, ML, 2004) |
| " Three studies are presented that provide preliminary evidence for the utility of the NPS for characterizing distinct pain qualities and changes in pain qualities in patients treated with the lidocaine patch 5% for a variety of neuropathic and non-neuropathic chronic pain conditions, including low-back pain, osteoarthritis, post-herpetic neuralgia, and painful diabetic neuropathy." | 3.72 | Introduction: chronic pain studies of the lidocaine patch 5% using the Neuropathic Pain Scale. ( Jensen, MP, 2004) |
| "Parenteral lidocaine has been reported to relieve neuropathic pain and/or pain refractory to opioid therapy." | 3.72 | Intravenous lidocaine relieves severe pain: results of an inpatient hospice chart review. ( Cox, MC; Kronenberg, R; Naco, GC; Thomas, J; von Gunten, CF; Wallace, M, 2004) |
| "The addition of alfentanil or atracurium to lidocaine solution for intravenous regional anaesthesia of the arm may have advantages with respect to improved muscle relaxation and better analgesia." | 3.71 | Effects of adding alfentanil or atracurium to lidocaine solution for intravenous regional anaesthesia. ( Aygünes, B; Kurt, I; Kurt, N; Oral, H; Tulunay, M, 2002) |
| "This study examined the safety, tolerability, and efficacy of iontophoresis with 30 mA of lidocaine for dermal anesthesia in children younger than 84 months in the emergency department and the usefulness of a modified version of the Pre-verbal, Early Verbal Pediatric Pain Scale (M-PEPPS)." | 3.71 | Safety, tolerability, and efficacy of iontophoresis with lidocaine for dermal anesthesia in ED pediatric patients. ( Jordan, P; Schultz, AA; Strout, TD; Worthing, B, 2002) |
| " Rats implanted subcutaneously with pellets or osmotic minipumps delivering morphine displayed time-related tactile allodynia and thermal hyperalgesia (i." | 3.71 | Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance. ( Lai, J; Malan, TP; Ossipov, MH; Porreca, F; Suenaga, NM; Vanderah, TW, 2001) |
| " Injection of subconjunctival cefuroxime can be very painful, especially after phacoemulsification under topical anesthesia." | 3.71 | Topical anesthesia for phacoemulsification and painless subconjunctival antibiotic injection. ( Dinakaran, S; Kayarkar, VV, 2001) |
| "Lidocaine infiltration was performed if any sign of pain was observed." | 3.71 | [Suture of skin lacerations using LAT gel (lidocaine, adrenaline, tetracaine)]. ( Alió Y Sanz, JL; Chipont Benabent, E; García-Hermosa, P, 2001) |
| " In 55% of group 2 patients the level of pain during the procedure was significant but bearable, in 35% it was considered unbearable and in 10% sedation with midazolam was necessary." | 3.71 | A single injection of lidocaine as local anesthesia for ultrasound guided needle biopsy of the prostate. ( Benetti, A; Giusti, G; Graziotti, P; Maffezzini, M; Seveso, M; Taverna, G, 2002) |
| "Repeated application of capsaicin on the tongue has been used as a human oral pain model to assess topical anesthetic-analgesic drugs." | 3.71 | A human oral capsaicin pain model to assess topical anesthetic-analgesic drugs. ( Dallel, R; Dubray, C; Ngom, PI; Woda, A, 2001) |
| "Lidocaine patch 5% comprises a soft, stretchy adhesive patch (l0 by 14 cm) containing 5% lidocaine (700 mg) for the topical treatment of pain associated with postherpetic neuralgia (PHN)." | 3.70 | Lidocaine patch 5%. ( Comer, AM; Lamb, HM, 2000) |
| "Eighty-five patients (90%), responders to lidocaine, had a pain relief and 71 patients (85%), no responders to lidocaine, did not have improvement by taking oral drugs." | 3.70 | [The predictive lidocaine test in treatment of neuropathic pain]. ( Trentin, L; Visentin, M, 2000) |
| " To assess whether these agents have a role in the treatment of visceral pain, the present study examined the effects of intravenous lidocaine on neuronal and reflex responses to colorectal distension." | 3.70 | Intravenous lidocaine inhibits visceral nociceptive reflexes and spinal neurons in the rat. ( Ness, TJ, 2000) |
| " Specifically, the actions of brainstem cholecystokinin and the possible importance of sustained afferent input from injured nerve fibers were determined using pharmacological and physiological approaches in rats with SNL." | 3.70 | Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat. ( Kovelowski, CJ; Lai, J; Malan, TP; Ossipov, MH; Porreca, F; Sun, H, 2000) |
| "Lidocaine may be useful in the treatment of neuropathic pain states." | 3.69 | Prolonged alleviation of tactile allodynia by intravenous lidocaine in neuropathic rats. ( Bach, FW; Chaplan, SR; Shafer, SL; Yaksh, TL, 1995) |
| " Recently, observations have been made that associate the use of hyperbaric lidocaine with bilateral leg pain." | 3.69 | Bilateral leg pain following lidocaine spinal anaesthesia. ( Chadwick, HS; Lowmiller, M; Pinczower, GR; Woodland, R, 1995) |
| "Pain at the site of propofol injection is a real problem which requires particular attention in children." | 3.69 | [Pain associated with the injection of Diprivan]. ( Banssillon, V, 1994) |
| "Epidural analgesia with local anesthetics administered alone or in combination with fentanyl effectively and safely treats the pain of sickle cell vaso-occlusive crisis unresponsive to conventional pain management and does so without causing sedation, respiratory depression, or significant limitation on ambulation." | 3.69 | Epidural analgesia in the management of severe vaso-occlusive sickle cell crisis. ( Billett, C; Casella, JF; Dover, G; Tobin, JR; Yaster, M, 1994) |
| "We evaluate the analgesic efficacy and safety of 9% (wt/vol) lidocaine (base) in petrolatum/paraffin ointment in patients with acute herpes zoster." | 3.69 | Treatment of the cutaneous pain of acute herpes zoster with 9% lidocaine (base) in petrolatum/paraffin ointment. ( Cork, RC; Dunston, A; Eyrich, J; Heitler, D; Johnson, W; Lopez-Anaya, A; Naraghi, M; Ragan, A; Riopelle, AJ; Riopelle, J, 1994) |
| " We have found that the pain usually associated with intradermal injection of lidocaine is attenuated by the addition of sodium bicarbonate." | 3.69 | Alkalinization of local anesthesia with sodium bicarbonate--preferred method of local anesthesia. ( Armel, HE; Horowitz, M, 1994) |
| "Lidocaine administered intravenously is efficacious in treating neuropathic pain at doses that do not cause sedation or other side effects." | 3.69 | Derivation and cross-validation of pharmacokinetic parameters for computer-controlled infusion of lidocaine in pain therapy. ( Brose, W; Gaeta, R; Gregg, KM; Minto, CF; Schnider, TW; Shafer, SL, 1996) |
| "Significant changes were found for pain assessment, local anesthesia procedures, and nitrous oxide administration." | 3.69 | [Pain in lumbar puncture. Results of a 2-year discussion at the French Society of Pediatric Oncology]. ( Annequin, D; Bouffet, E; Castaing, MC; Douard, MC; Pichard-Léandri, E, 1996) |
| "To assess the benefit of ketamine addition to a morphine-clonidine-lidocaine mixture administered continuously by the intrathecal route for the treatment of cancer pain." | 3.69 | [Cancer pain: beneficial effect of ketamine addition to spinal administration of morphine-clonidine-lidocaine mixture]. ( Lemos, D; Muller, A, 1996) |
| "We have assessed the effects of intraplantar local anaesthetics (bupivacaine and lignocaine) on carrageenan-induced oedema, mechanical allodynia and spinal c-fos protein expression." | 3.69 | Effects of local anaesthetics on carrageenan-evoked inflammatory nociceptive processing in the rat. ( Besson, JM; Buritova, J; Fletcher, D; Honoré, P, 1996) |
| " We report two cases of bilateral pain in the lower extremities appearing 20-24 h after intradural anesthesia with 2% hyperbaric lidocaine." | 3.69 | [Pain in the lower extremities after subarachnoid block with lidocaine]. ( Gómez, E; Masip, R; Rull, M; Sala, P; Saludes, J, 1996) |
| "In this study, 8 patients with central pain syndromes, 6 with hemispheric lesions, and 2 with spinal cord lesions were treated with a 1 mg/kg dose of intravenous lidocaine." | 3.68 | Response of central pain syndromes to intravenous lidocaine. ( Backonja, M; Gombar, KA, 1992) |
| "In this open, uncontrolled trial, 20 patients with upper trapezius muscle trigger point pain and ipsilateral masseter muscle pain received a single trigger point injection of 2% lidocaine solution (without epinephrine) in the upper trapezius muscle." | 3.68 | Reduction of pain and EMG activity in the masseter region by trapezius trigger point injection. ( Carlson, CR; Falace, DA; Lindroth, JE; Nitz, AJ; Okeson, JP, 1993) |
| "We analyzed retrospectively pain relief from an intravenous lidocaine infusion (5 mg/kg/hr for 60 to 90 minutes) in 111 patients with chronic nonmalignant pain." | 3.68 | Response to intravenous lidocaine infusion differs based on clinical diagnosis and site of nervous system injury. ( Galer, BS; Miller, KV; Rowbotham, MC, 1993) |
| "Phenazopyridine has been associated with methemoglobinemia in patients who have received an overdose, have decreased renal function, or are discovered to be unusually susceptible to the drug (ie, they may have an undetected NADH methemoglobin reductase deficiency)." | 3.68 | Acquired methemoglobinemia from multiple oxidants. ( Bailey, MK; Baker, JD; Conroy, JM; Dorman, BH; Martin, WJ, 1993) |
| "This prospective, nonblinded study, comparing jet injection with needle-syringe injection of lidocaine in performing digital blocks, tested the hypothesis that jet injection can be used effectively as a less painful way to perform digital blocks." | 3.68 | The efficacy and acceptability of using a jet injector in performing digital blocks. ( Ellis, GL; Owens, A, 1993) |
| "We have developed transdermally applicable 10% lidocaine aqueous gel containing an absorption promoter and applied it for 15 patients suffering from severe pain in acute or subacute phase of herpes zoster." | 3.68 | [Transdermal application of 10% lidocaine-gel for management of pain associated with herpes zoster]. ( Ikuta, Y; Kano, T; Mishima, M; Morioka, T; Nakano, M; Shimoda, O; Takaki, M; Tashima, T; Tashiro, M, 1993) |
| "The author studied the use of intravenous Propofol for the relief of pain." | 3.68 | [Changes in the pain produced by the peripheral venous injection of propofol when it is combined with lidocaine or fentanyl]. ( Croston, J; de Henriquez, L; de Jiménez, L; Espinosa, V, 1992) |
| "Lidocaine is often used as a topical analgesic prior to painful procedures performed in the oral cavity and upper airways." | 3.68 | Onset and duration of hypoalgesia of lidocaine spray applied to oral mucosa--a dose response study. ( Arendt-Nielsen, L; Bjerring, P; Schønemann, NK; van der Burght, M, 1992) |
| "The effect of pH neutralization on the pain experienced during intradermal lidocaine administration was investigated in a prospective blind study of 20 adult volunteers." | 3.68 | Neutralized lidocaine: use in pain reduction in local anesthesia. ( Bancroft, JW; Becker, GJ; Benenati, JF; Katzen, BT; Zemel, G, 1992) |
| "We studied usefulness of iontophoresis on pain relief using several Ca channel blockers, propranolol and guanethidine." | 3.68 | [Influence of calcium channel blockers and beta-blockers on pain relief with iontophoresis]. ( Honda, N; Ikebe, H; Miyagawa, A; Mizutani, A; Sendaya, K; Taniguchi, K; Yoshitake, S, 1992) |
| "Buffered lidocaine has been recently recommended for local anesthesia, as there is less pain on injection of the buffered solution." | 3.68 | Stability of buffered lidocaine and epinephrine used for local anesthesia. ( Carey, P; Darcey, B; Larson, PO; Polzin, G; Ragi, G; Swandby, M, 1991) |
| "The pain usually associated with intradermal injection of lidocaine and epinephrine is significantly attenuated by the addition of either sodium bicarbonate or sodium hydroxide to 1% lidocaine with epinephrine." | 3.68 | Neutralized lidocaine with epinephrine for local anesthesia--II. ( Chinn, SE; Cole, GW; Klein, JA; Stewart, JH, 1990) |
| "The analgesic effect of a lidocaine/prilocaine cream (EMLA) for the curettage of molluscum contagiosum was evaluated in 55 children aged 3-14 years." | 3.67 | Curettage of molluscum contagiosum in children: analgesia by topical application of a lidocaine/prilocaine cream (EMLA). ( Edmar, B; Gisslén, H; Lillieborg, S; Nordin, P; Rosdahl, I, 1988) |
| "A patient with disseminated cancer pain failed to obtain pain relief despite the intravenous infusion of hydromorphone at a rate equivalent to over 7 g of morphine/day." | 3.67 | Failure of epidural opioid to control cancer pain in a patient previously treated with massive doses of intravenous opioid. ( Cousins, MJ; Tanelian, DL, 1989) |
| "Diagnostic epidural blocks were performed on 27 chronic pain patients sequentially using saline, fentanyl, and lidocaine solution." | 3.67 | Diagnostic epidural opioid technique. ( Ellis, JS; Hoffman, J; Ramamurthy, S; Schoenfeld, LS; Walsh, NE, 1989) |
| "Intravenous infusion of lidocaine has a pain-relieving effect in patients with painful diabetic neuropathy." | 3.67 | Lidocaine treatment of painful diabetic neuropathy and endogenous opioid peptides in plasma. ( Angelo, H; Bach, FW; Dejgård, A; Ekman, R; Jensen, S; Kastrup, J; Petersen, P, 1989) |
| "The role of cingulum in the perception of tonic and phasic pain was examined by injecting lidocaine, a local anesthetic, into the anterior cingulum bundle of the rat." | 3.67 | Analgesia produced by injection of lidocaine into the anterior cingulum bundle of the rat. ( Melzack, R; Vaccarino, AL, 1989) |
| "The local anesthetic lidocaine was injected into the lateral hypothalamus (LH) of awake, freely moving rats immediately prior to pain testing with either the formalin or the foot-flick test." | 3.67 | Analgesia produced by injection of lidocaine into the lateral hypothalamus. ( Choinière, M; Libman, SM; Melzack, R; Tasker, RAR, 1987) |
| "Assessment of pain on injection of the emulsified formulation of di-isopropylphenol (propofol, 'Diprivan') was undertaken in 120 unpremedicated patients and comparison made with thiopentone." | 3.67 | Assessment and modification of pain on induction with propofol (Diprivan). ( Lees, NW; McCulloch, MJ, 1985) |
| "A 62-year-old man who was under observation following an episode of severe chest pain developed complete heart block and hypotension after receiving sublingual nitroglycerin." | 3.66 | Complete heart block after sublingual nitroglycerin. ( Fenster, PE; Lancaster, L, 1983) |
| "We studied the effect of depth of lidocaine injection into the skin, rate of injection, and temperature of the solution on pain experienced." | 3.66 | Minimizing the pain of local anesthesia. ( Arndt, KA; Burton, C; Noe, JM, 1983) |
| "The effects of lidocaine 2% infiltration on the brain-evoked potential elicited by painful dental stimulation were observed in human subjects." | 3.66 | Effects of local anesthetic infiltration on brain potentials evoked by painful dental stimulation. ( Chapman, CR; Colpitts, YH; Gehrig, JD, 1981) |
| "Lidocaine (60 mg/100 ml) was added to contrast medium (120 ml of Conray-60) in an attempt to decrease pain associated with leg venography in 100 patients." | 3.66 | Intravenous lidocaine: an effective analgesic for lower extremity venography. ( Duncan, TR; Gerlock, AJ; Nickell, LR, 1979) |
| "In various chronic painful states, the sympathetic nerve supply was blocked either by injecting the sympathetic chain and ganglia with local anaesthesia or by the injection of guanethidine during occlusion of the circulation." | 3.66 | Painful peripheral states and sympathetic blocks. ( Loh, L; Nathan, PW, 1978) |
| "In 50 patients subjected to aorto-femoral arteriography, the examination was carried out with and without the addition of 1 cm3 of 2% lidocaine per 10 cm3 of contrast medium; in 43/50 lidocaine led to a more or less notable reduction in pain without side-effects." | 3.66 | [The intra-arterial use of lidocaine to reduce pain in aorto-femoral arteriography (author's transl)]. ( Caresano, A; Del Favero, C; Lanocita, M; Magistretti, G; Martinenghi, CO; Neri, C, 1978) |
| " After the anesthetic effect had subsided, prilocaine 4% caused post-analgesic pain less frequently than did lidocaine 2% with adrenalin 12." | 3.65 | Pain and temperature sensations related to local analgesia. ( Evers, H; Oikarinen, VJ; Ylipaavalniemi, P, 1975) |
| "Intra-arterial lidocaine was found to be an effective and safe method for reducing pain associated with peripheral angiography." | 3.65 | Intra-arterial lidocaine: an effective analgesic for peripheral angiography. ( Gordon, IJ; Westcott, JL, 1977) |
| " For unanesthetized tubes the mean pain rating depended on the dose of diazepam and fentanyl given to the patient (p less than ." | 3.65 | Laparoscopic tubal clip sterilization under local anesthesia. ( Edelman, DA; Fishburne, JI; Hulka, JF; Mercer, JP; Omran, KF, 1974) |
| "Surgical incisions were infiltrated subcutaneously with lidocaine without adrenaline or NaCl (placebo)." | 3.30 | Evaluation of primary wound healing and potential complications after perioperative infiltration with lidocaine without adrenaline in surgical incisions in dogs and cats. ( Bergström, AF; Engdahl, KS; Herlofson, EAG; Tavola, F, 2023) |
| "Pain was measured using the Visual Analogue Scale." | 3.30 | Pain Relief Durations of Different Concentrations of Lidocaine in Wide Awake Hand Surgery: A Prospective Randomised Clinical Trial. ( Ahmad, H; Bashir, MM; Jan, SN; Shami, HB; Tayab, Z, 2023) |
| "Pain is the most common cause of office hysteroscopy (OH) failure." | 3.30 | Nonsteroidal anti-inflammatory drug with a local anesthetic compared to nonsteroidal anti-inflammatory drug alone significantly reduce the pain associated with vaginoscopic office hysteroscopy. ( Babczyk, D; Baran, R; Gawron, I; Jach, R; Pietrus, M; Zmaczynski, A, 2023) |
| "Lidocaine gel was an effective drug that can be used to attenuate the incidence rate of post-operative sore throat." | 3.30 | Comparing the effectiveness of topical dexamethasone emollient, lidocaine gel, and glycerin emollient on the endotracheal tube for postoperative hoarseness of voice, sore throat, and laryngospasm. ( Jabbar, ML; Mahboba, JH; Meazher, N, 2023) |
| "Lidocaine spray treatments were significantly different in the gag reflex (NRS; Gp A: 1." | 3.11 | Comparative effectiveness of lidocaine sprays between sitting and supine position for patients undergoing upper gastrointestinal endoscopy: a prospective randomized controlled trial. ( Mahawongkajit, P; Soonthornkes, N, 2022) |
| "Provoked vestibulodynia (PVD) is a chronic vulvovaginal pain condition affecting 8%-10% of women and is associated with negative sexual sequalae." | 3.11 | Sexual communication mediates cognitive-behavioral couple therapy outcomes: A randomized clinical trial for provoked vestibulodynia. ( Bergeron, S; Delisle, I; Lee-Baggley, D; Rancourt, KM; Rosen, NO; Vaillancourt-Morel, MP, 2022) |
| "Lidocaine has been gradually used in general anesthesia." | 3.11 | Effect of Systemic Lidocaine on Postoperative Early Recovery Quality in Patients Undergoing Supratentorial Tumor Resection. ( Chen, X; Cui, X; Dong, Y; Ji, T; Li, W; Su, G; Wang, Y; Wu, N; Yang, Y; Zhao, K, 2022) |
| "Cutaneous warts are treated by different treatments with various efficacy." | 3.11 | Comparison of the efficacy of intralesional 5-fluorouracil/lidocaine/epinephrine injection with cryotherapy to treat common and palmoplantar warts: A randomized, controlled trial. ( Bagheri, Z; Sarani, MB; Sepaskhah, M, 2022) |
| "This pain is not only distressing to the patient and his or her parents, but often reflects poorly on an otherwise well performed procedure." | 3.11 | The application of xylocaine 10% pump-spray to improve immediate post-adenotonsillectomy pain in children: A randomized controlled trial. ( Opperman, JB; Tshifularo, MI, 2022) |
| "This study aims to investigate the effect of compound topical anesthetic (CTA) application combined with photobiomodulation therapy (PBMT) on the level of pain perceived during placement of miniscrews and 24 h post the procedure in the buccal side of the maxillary bone." | 3.11 | Efficacy of compound topical anesthesia combined with photobiomodulation therapy in pain control for placement of orthodontic miniscrew: a double-blind, randomized clinical trial. ( Chiniforush, N; Cronshaw, M; Dadgar, S; Navaei, RA; Noroozian, M; Rakhshan, V; Saravani, HJ; Sobouti, F, 2022) |
| "5 mg/kg) combined with lidocaine (2 mg/kg) or lidocaine (2 mg/kg) only (control treatment)." | 3.01 | Neuraxial administration of morphine combined with lidocaine induces regional antinociception in inland bearded dragons (Pogona vitticeps). ( Ferreira, TH; Fink, DM; Mans, C, 2021) |
| "Anterior shoulder dislocations are commonly seen in the emergency department for which several closed reduction techniques exist." | 3.01 | Effects of reduction technique for acute anterior shoulder dislocation without sedation or intra-articular pain management: a systematic review and meta-analysis. ( Baden, DN; Groenwold, RHH; Houwert, RM; Roetman, MH; Smeeing, DPJ; van der Meijden, OAJ; Visser, MFL, 2023) |
| "Pregnancy is characterized by complex physiological changes, and increased sensitivity to pain." | 3.01 | Physiology of pregnancy and oral local anesthesia considerations. ( Pan, J; Pan, Z; Zhang, J; Zhong, Y; Zhou, X, 2023) |
| "Forty volunteers with moderate to severe chronic periodontitis were recruited, of which at least three sextants required periodontal therapy." | 2.94 | Liposomal anesthetic gel for pain control during periodontal therapy in adults: a placebo-controlled RCT. ( Farago, PV; Moraes, GS; Pilatti, GL; Pinto, SCS; Pochapski, MT; Santos, FA; Santos, IBD, 2020) |
| " A total of 29 treatment related adverse events were reported by 16% of subjects, all were mild (79%) or moderate (21%) in intensity." | 2.94 | Safety and Effectiveness of Hyaluronic Acid Fillers With Lidocaine for Full-Face Treatment in Asian Patients. ( Huang, SH; Tsai, TF, 2020) |
| "Pain was assessed on a visual analogue scale and a verbal rating scale." | 2.90 | Efficacy of buffered local anaesthetics in head and neck infections. ( Arora, G; Dasukil, S; Degala, S, 2019) |
| "Pain was assessed subjectively using the numeric rating scale (NRS) and objectively using a Galvanic Skin Response (GSR) tester." | 2.87 | [The Effect of Pain Relieving Intervention During Infiltration among Gamma Knife Surgery Patients for Stereotactic Frame Fixation]. ( Jang, YJ; Kim, HO, 2018) |
| "Pain is similarly reduced for periocular botulinum toxin injections reconstituted with preserved saline compared with unpreserved saline." | 2.82 | Bacteriostatic preserved saline for pain-free periocular injections: review. ( Hunt, SV; Malhotra, R, 2022) |
| "Lidocaine was superior in analgesic effect to prilocaine in IVRA in one study." | 2.82 | Comparative efficacy of anaesthetic methods for closed reduction of paediatric forearm fractures: a systematic review. ( Chong, SL; Gao, JF; Goh, AXC; Ho, AFW; Ong, MEH; Siddiqui, FJ; Yeo, JW, 2022) |
| "Lidocaine spray treatment significantly lowered the pain scores compared with placebo (p < 0." | 2.82 | Effect of lidocaine spray in pain management during office-based endometrial sampling: A randomised placebo-controlled trial. ( Acmaz, G; Aksoy, H; Aksoy, U; Aydin, T; Babayigit, MA; Ozyurt, S; Yücel, B, 2016) |
| "Pain was evaluated with Visual Analog Scale, when the cervical canal was passed, while within the cavity and at 10 min after procedure." | 2.82 | The Effect of Intrauterine Lidocaine and Rectal Indomethacin on Pain during Office Vaginoscopic Hysteroscopy: Randomized Double-Blind Controlled Study. ( Babaoğlu, B; Guraslan, H; Polat, M; Senturk, MB; Yaşar, L, 2016) |
| "Injection pain was measured immediately after local infiltration anesthesia using the visual analog pain scale (VAS) questionnaire." | 2.82 | Relief of Injection Pain During Delivery of Local Anesthesia by Computer-Controlled Anesthetic Delivery System for Periodontal Surgery: Randomized Clinical Controlled Trial. ( Chang, H; Kim, S; Kim, TI; Koo, KT; Ku, Y; Lee, J; Lee, YM; Noh, J; Rhyu, IC; Seol, YJ, 2016) |
| "Pain was effectively controlled in both groups." | 2.80 | Ultrasound-guided hematoma block in distal radial fracture reduction: a randomised clinical trial. ( Abbasi, S; Farsi, D; Fathi, M; Hafezimoghadam, P; Moezzi, M; Zare, MA, 2015) |
| "Pain was continuously recorded during stimulation, and measures of subjective stress and blood pressure were obtained before the pretest, after the application of cream, and after the posttests." | 2.80 | Opposite effects of the same drug: reversal of topical analgesia by nocebo information. ( Aslaksen, PM; Bjørkedal, E; Eilertsen, HH; Gorecka, MM; Zwarg, ML, 2015) |
| " Most common treatment-emergent adverse events (AEs) included lip bruising, swelling, and pain and were mostly mild and transient in nature, without anticipated device AEs." | 2.80 | A randomized, evaluator-blinded, controlled study of effectiveness and safety of small particle hyaluronic acid plus lidocaine for lip augmentation and perioral rhytides. ( Beer, K; Bulley, B; Dover, JS; Glogau, RG; Handiwala, L; Olin, JT; Shamban, A, 2015) |
| " Safety assessments included adverse events (AEs) and relationship to study treatment." | 2.80 | Safety and Efficacy of a Needle-free Powder Lidocaine Delivery System in Pediatric Patients Undergoing Venipuncture or Peripheral Venous Cannulation: Randomized Double-blind COMFORT-004 Trial. ( Meyer, JM; Schmitz, ML; Zempsky, WT, 2015) |
| "Primary mechanical hyperalgesia at the shoulders and buttocks decreased significantly more after lidocaine than saline injections (p = 0." | 2.79 | Analgesic and anti-hyperalgesic effects of muscle injections with lidocaine or saline in patients with fibromyalgia syndrome. ( Bartley, E; Price, DD; Robinson, ME; Staud, R; Weyl, EE, 2014) |
| "AMSA and P-ASA approaches were used with CIT." | 2.79 | Pain sensation and injection techniques in maxillary dento-alveolar surgery procedures in children--a comparison between conventional and computerized injection techniques (The Wand). ( Jälevik, B; Klingberg, G, 2014) |
| "Lidocaine gel at concentrations from 2 to 12% induced similar anesthetic effect for IVTs, without adverse effects on cornea and conjunctiva." | 2.79 | Safety and efficacy of various concentrations of topical lidocaine gel for intravitreal injection. ( Farah, ME; Grumann, A; Lorenzo, JC; Nunes, RP; Penha, FM; Rodrigues, EB; Shiroma, HF, 2014) |
| "Then, pain was induced in each patient's forearm by introducing a 27 G needle into the skin 4 mm deep three times." | 2.79 | The use of skin needling for the delivery of a eutectic mixture of local anesthetics. ( De Vita, V; Fabbrocini, G; Izzo, R; Monfrecola, G, 2014) |
| "Pain and potential adverse events (AE) remain challenges for patients being treated with calcium hydroxylapatite (CaHA; Radiesse), especially CaHA not mixed with an anesthetic." | 2.79 | Safety and effectiveness of injection of calcium hydroxylapatite via blunt cannula compared to injection by needle for correction of nasolabial folds. ( Beer, KR, 2014) |
| "Pain was assessed using Wong-Baker faces pain rating scale (WBFPRS) and faces legs activity cry and consolability (FLACC) painscale." | 2.79 | Efficacy of lignocaine in gel and spray form during buccal infiltration anesthesia in children: a randomized clinical trial. ( Rao, A; Sharma, A; Shenoy, R; Suprabha, BS, 2014) |
| "Pain of solution deposition and postoperative pain were also measured." | 2.78 | Anesthetic efficacy of a combination of 0.5 M mannitol plus 127.2 mg of lidocaine with 50 μg epinephrine in inferior alveolar nerve blocks: a prospective randomized, single-blind study. ( Beck, M; Drum, M; Nusstein, J; Reader, A; Smith, S, 2013) |
| "Pain was evaluated using 10-point Visual Analog Scale (VAS)." | 2.78 | A prospective randomized trial comparing three different analgesic techniques for pain control during transrectal ultrasound guided prostate biopsy: a single center experience. ( Anup, K; Biswajit, N; Nayan, MK; Niraj, K; Pawan, V, 2013) |
| "Pain was evaluated using a visual analog scale." | 2.78 | The evaluation of hyaluronic acid, with and without lidocaine, in the filling of nasolabial folds as measured by ultrastructural changes and pain management. ( Cornejo, P; Cruz, I; Isarría, MJ; Moreno-Moraga, J; Muñoz, E; Pérez, G; Royo de la Torre, J, 2013) |
| "We enrolled 23 patients with piriformis syndrome, proposing a percutaneous intramuscular injection of methylprednisone-lidocaine." | 2.77 | Piriformis syndrome: long-term follow-up in patients treated with percutaneous injection of anesthetic and corticosteroid under CT guidance. ( Calabria, E; Crusco, S; Masala, S; Meschini, A; Simonetti, G; Taglieri, A, 2012) |
| "Pain was assessed by visual analogue scale (VAS) and anxiety levels by the State-Trait Anxiety Inventory (STAI-I and STA-II)." | 2.77 | No effect of perianal application of topical anaesthetic on patient comfort during nonsedated flexible sigmoidoscopy: a randomized, placebo-controlled clinical trial. ( Boyacioglu, S; Cengiz, C; Kuzu, MA; Ozdemir, B; Pampal, HK, 2012) |
| "Propofol is a widely used anesthetic drug because of its minor complication and also its fast effect." | 2.77 | Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial. ( Ayatollahi, V; Behdad, S; Kargar, S; Yavari, T, 2012) |
| "Lidocaine was injected around the neurovascular bundle at the base of the prostate just lateral to the seminal vesicle-prostate junction." | 2.76 | Transrectal ultrasound guided multi-core prostate biopsy: pain control: results of 106 patients. ( Donmez, H; Kahriman, G; Kenan, B; Mavili, E; Ozcan, N; Yilmaz, SP, 2011) |
| "Pain was assessed at 2 phases: during venipuncture (from needle introduction to its removal) and during the recovery period (30 seconds after needle removal)." | 2.76 | Analgesic effects of EMLA cream and oral sucrose during venipuncture in preterm infants. ( Biran, V; Carbajal, R; Cimerman, P; Gourrier, E; Mitanchez, D; Walter-Nicolet, E, 2011) |
| "The mean pretreatment pain score was 6." | 2.75 | The efficacy of a topical anesthetic gel in the relief of pain associated with localized alveolar osteitis. ( Burgoyne, CC; Giglio, JA; Laskin, DM; Reese, SE; Sima, AP, 2010) |
| " Adverse events were recorded." | 2.75 | Safety of lidocaine 15% and prilocaine 5% topical ointment used as local anesthesia for intense pulsed light treatment. ( Carruthers, JA; Carruthers, JD; Mordaunt, J; Oliff, HS; Poirier, J; Schreiber, WE, 2010) |
| "Opioid-refractory pain is distressing because it is notoriously difficult to treat." | 2.74 | A phase II pilot study to evaluate use of intravenous lidocaine for opioid-refractory pain in cancer patients. ( Haji, AG; Jain, D; Palat, G; Rajagopal, MR; Sharma, S; Singh, C, 2009) |
| "To compare the efficacy of periprostatic nerve block (PNB) alone vs PNB combined with the local administration of a 1." | 2.74 | Periprostatic nerve block (PNB) alone vs PNB combined with an anaesthetic-myorelaxant agent cream for prostate biopsy: a prospective, randomized double-arm study. ( Cantiello, F; Di Meo, S; Fusco, F; Iannuzzo, M; Imbimbo, C; Imperatore, V; Mirone, V; Scibelli, G, 2009) |
| "Fibromyalgia Impact Questionnaire (FIQ), Health Assessment Questionnaire, and a visual analog scale (VAS) for pain were applied before the first lidocaine infusion, immediately after the fifth infusion and 30 days after the fifth infusion." | 2.74 | Intravenous lidocaine for fibromyalgia syndrome: an open trial. ( Harth, F; Kaiber, F; Machado, F; Malucelli, T; Schafranski, MD; Schmidt, C; Takeshi, H, 2009) |
| "Referred pain is a significant clinical problem, and commonly occurs with pain originating in muscle but not from skin." | 2.74 | Effects of intramuscular anesthesia on the expression of primary and referred pain induced by intramuscular injection of hypertonic saline. ( Gandevia, SC; Henderson, LA; Macefield, VG; Rubin, TK, 2009) |
| "After induction of pin-prick hyperalgesia lidocaine or placebo was administered systemically using a double-blinded design." | 2.74 | Medial prefrontal cortex activity is predictive for hyperalgesia and pharmacological antihyperalgesia. ( Bschorer, K; De Col, R; Filitz, J; Koppert, W; Maihöfner, C; Peltz, E; Seifert, F, 2009) |
| "Pain was assessed by Visual Analogue Scale (VAS) on two different days after skin application of EMLA or placebo cream on the forearms." | 2.74 | Pregnancy at term does not alter the responses to a mechanical and an electrical stimulus after skin EMLA application. ( Fassoulaki, A; Katafigioti, A; Paraskeva, A; Petropoulos, G; Siafaka, I, 2009) |
| "The diphenhydramine solution was irritating on injection and postinjection and resulted in a very low level of anesthetic success." | 2.73 | The anesthetic efficacy of diphenhydramine and the combination diphenhydramine/lidocaine for the inferior alveolar nerve block. ( Beck, M; Drum, M; Nusstein, J; Reader, A; Willett, J, 2008) |
| "Sedation-free intradetrusor botulinum toxin-A injection using intravesical lidocaine and flexible endoscopy is a well tolerated and safe procedure to perform in an office setting." | 2.73 | Safety and tolerability of sedation-free flexible cystoscopy for intradetrusor botulinum toxin-A injection. ( Barboglio, P; Cohen, BL; Gousse, A; Rivera, R, 2007) |
| "Pain was recorded on 100 mm visual analogue scales (VAS) after lignocaine injection or ethyl chloride spray and following i." | 2.73 | Lignocaine is a better analgesic than either ethyl chloride or nitrous oxide for peripheral intravenous cannulation. ( Carr, S; Frampton, C; Pearson, S; Robinson, PA, 2007) |
| "Various anesthetic approaches have been used to make cystoscopy more tolerable for patients." | 2.73 | Patient tolerance during cystoscopy: a randomized study comparing lidocaine hydrochloride gel and dimethyl sulfoxide with lidocaine. ( Bedir, S; Demir, E; Erken, U; Kilciler, M, 2008) |
| " Neither anesthetic was systemically absorbed in any cat, and no adverse clinical signs were observed." | 2.72 | Adverse effects of EMLA (lidocaine/prilocaine) cream and efficacy for the placement of jugular catheters in hospitalized cats. ( Gibbon, KJ; Kurian, JR; Strom, TL; Trepanier, LA; Wagner, KA, 2006) |
| "Lidocaine plasma levels were assessed at 0 and 2 h." | 2.72 | Study of a combined percutaneous local anaesthetic and the TDS system for venepuncture. ( Alam, CA; Chik, Z; Johnston, A; Kirby, K; Michaels, L; Seed, MP; Tucker, AT, 2006) |
| "Duration of numbness of soft tissues was significantly longer for articaine (3." | 2.72 | Comparison of articaine 4% and lidocaine 2% in paediatric dental patients. ( Amir, E; Ram, D, 2006) |
| "Lidocaine is a local anaesthetic with analgesic but no anti-inflammatory properties." | 2.72 | Lidocaine iontophoresis mediates analgesia in lateral epicondylalgia treatment. ( Ferslew, KE; Kalbfleisch, JH; Panus, PC; Yarrobino, TE, 2006) |
| "Pain was rated during the biopsy, diagnostic investigation, and injection of lidocaine." | 2.71 | Periprostatic administration of local anesthesia during transrectal ultrasound-guided biopsy of the prostate: a randomized, double-blind, placebo-controlled study. ( Bartsch, G; Berger, AP; Frauscher, F; Halpern, EJ; Horninger, W; Spranger, R; Steiner, H, 2003) |
| "Lidocaine was injected through a 7-inch spinal needle placed through a transrectal ultrasound biopsy guide." | 2.71 | Periprostatic local anesthesia eliminates pain of office-based transrectal prostate biopsy. ( Angie, S; Horvat, M; Jones, JS; Kitay, R; Klein, EA; Kursh, ED; Nelson, D; Ulchaker, JC; Zippe, CD, 2003) |
| "Lidocaine iontophoresis is a method of topical anesthesia in which lidocaine is driven into the skin under the influence of electric current." | 2.71 | Lidocaine iontophoresis for local anesthesia before shave biopsy. ( Parkinson, TM; Zempsky, WT, 2003) |
| "Scarring was not observed." | 2.71 | Full-face laser resurfacing using a supplemented topical anesthesia protocol. ( Calkin, J; Chotzen, V; Kilmer, SL; McClaren, M; No, D; Silva, S; Zelickson, BD, 2003) |
| "Pain was recorded by the patient using a 100-mm nongraphic rating visual analogue scale." | 2.71 | Is using lignocaine gel prior to flexible cystoscopy justified? A randomized prospective study. ( Ashurst, HN; Biyani, CS; Elmasray, Y; Palit, V; Puri, R; Shah, T, 2003) |
| "Of the 305 women approached, 300 women were randomised into the study." | 2.71 | Randomised comparison of distension media for outpatient hysteroscopy. ( Davidson, A; Habiba, M; Shankar, M; Taub, N, 2004) |
| "Pain was assessed with a Visual Analog Scale, during anaesthesia (VAS 1), during the biopsies procedure (VAS 2) and 30 minutes after them (VAS 3)." | 2.71 | [Comparison of two methods of local anaesthesia prior to transrectal ultrasound-guided prostate biopsies]. ( Alexis, G; Blanchet, P; Braud, F; Clervil, M; Fofana, M; Humbert, M; Mallick, S, 2004) |
| "Pain was assessed with the Newborn Acute Pain scale (DAN) and with the Neonatal Facial Coding System (NFCS)." | 2.71 | [Analgesic effects of Emla cream and saccharose solution for subcutaneous injections in preterm newborns: a prospective study of 265 injections]. ( Baudon, JJ; Ducrocq, S; Gold, F; Lebas, F; Mochel, F; Mucignat, V, 2004) |
| "The lidocaine patch 5% was generally well tolerated and no patients discontinued due to treatment-related adverse events." | 2.71 | Topical lidocaine patch 5% may target a novel underlying pain mechanism in osteoarthritis. ( Burch, F; Codding, C; Galer, BS; Gammaitoni, AR; Patel, N; Sheldon, E, 2004) |
| " The primary outcome measure was reduction in ureteral stent symptoms, and the secondary outcome measure was the safety of intravesical instillation of each agent through assessment of drug-related adverse events." | 2.71 | Double-blind randomized controlled trial assessing the safety and efficacy of intravesical agents for ureteral stent symptoms after extracorporeal shockwave lithotripsy. ( Beiko, DT; Brock, GB; Denstedt, JD; Knudsen, BE; Nott, L; Pautler, SE; Razvi, H; Watterson, JD, 2004) |
| " Immediately following the procedure, the subjects, the investigator, and an independent observer rated pain intensity and adverse events were recorded." | 2.71 | Self-warming lidocaine/tetracaine patch effectively and safely induces local anesthesia during minor dermatologic procedures. ( Berman, B; de Araujo, T; Flores, J; Pariser, D; Pariser, R; Ramirez, CC, 2005) |
| "If fentanyl was given with the lidocaine in the para-cervical block, it potentially could improve pain control while decreasing side effects and avoiding i." | 2.71 | Intra-cervical versus i.v. fentanyl for abortion. ( Savoy, E; Trouton, KJ; Wiebe, ER, 2005) |
| " In groups 6 and 7, additional fentanyl doses were lower than in the other groups, but only in group 7 was the total fentanyl dosage low." | 2.71 | Effectiveness of eutectic mixture of local anesthetic cream and occlusive dressing with low dosage of fentanyl for pain control during shockwave lithotripsy. ( Basar, H; Basar, MM; Batislam, E; Ozcan, S; Tuglu, D; Yilmaz, E, 2005) |
| "Pain was evaluated using a visual analog scale (VAS) after each core biopsy." | 2.71 | Local anesthesia in transrectal ultrasound-guided prostate biopsy: EMLA cream as a new alternative technique. ( Akpinar, S; Başar, H; Başar, MM; Batislam, E; Ozcan, S, 2005) |
| "The magnesium-lignocaine treatment was painful in 52% of patients compared with 8% with lignocaine alone (number-needed-to-harm 2." | 2.70 | Magnesium Bier's block for treatment of chronic limb pain: a randomised, double-blind, cross-over study. ( Glynn, CJ; Tramèr, MR, 2002) |
| "The results indicate that muscle fasciculation was not found in Group PR while the patients in Group LS had a lower incidence of muscle fasciculation than those in Group PS (p < 0." | 2.70 | Can lidocaine reduce succinylcholine induced postoperative myalgia? ( Amornyotin, S; Nilsuwankosit, P; Pipatnaraphong, H; Rachatamukayanant, P; Santawat, U, 2002) |
| "The pain was especially marked intraoperatively, less so 30 minutes post-operatively." | 2.70 | Pain relief using paracervical block in patients undergoing manual vacuum aspiration of uterus. ( Egziabher, TG; Ruminjo, JK; Sekadde-Kigondu, C, 2002) |
| "Perineal pain is one of the most common causes of maternal morbidity in the early puerperium." | 2.70 | Reducing postnatal pain from perineal tears by using lignocaine gel: a double-blind randomized trial. ( Alfirevic, Z; Corkill, A; Lavender, T; Walkinshaw, SA, 2001) |
| "There were no reports of numbness of the tongue, lip, or cheek, neither were there any adverse local reactions in the oral mucosa." | 2.70 | The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraqix) for periodontal scaling/root planing. ( Friskopp, J; Isacsson, G; Nilsson, M, 2001) |
| "The pain was measured using a 100 mm visual analogue scale." | 2.70 | The use of pre-cannulation local anaesthetic and factors affecting pain perception in the emergency department setting. ( Cameron, PA; Harris, T; Ugoni, A, 2001) |
| "Pain was scored subjectively by each patient (0-10) during the injection, peroperatively and postoperatively." | 2.70 | [Comparison between Greenbaum's parabulbar anesthesia and Ripart's subtenon anesthesia in the anterior segment surgery]. ( Alberti, M; Baltenneck, A; Batisse, JL; de la Marnierre, E; Mage, F, 2002) |
| "Pain was assessed using a linear analogue scale from 0 to 10." | 2.70 | Photodynamic therapy for superficial bladder cancer under local anaesthetic. ( Betts, CD; Briggs, C; Clarke, NW; Gilhooley, A; Moore, JV; O'Flynn, KJ; Shackley, DC; Whitehurst, C, 2002) |
| "The pain was rated by each patient on a 100-mm visual analogue scale (VAS)." | 2.69 | Lidocaine-prilocaine cream (EMLA Cream) as a topical anaesthetic for the cleansing of leg ulcers. The effect of length of application time. ( Holst, RG; Kristofferson, A, 1998) |
| "Pain was less severe in the EMLA group than in the lidocaine infiltration group (Score of 2 vs 7; P = 0." | 2.69 | Topical lidocaine-prilocaine cream (EMLA) versus local infiltration anesthesia for radial artery cannulation. ( Ali, OS; Benhamou, D; Joly, LM; Monchi, M; Spaulding, C; Weber, S, 1998) |
| "Pain was evaluated on a visual analog scale (VAS, 0-10)." | 2.69 | [Efficacy of EMLA cream, effect of time and place of application]. ( Cano Serrano, ME; Martínez-Tellería, A; Rufino Ruiz, J, 1999) |
| "Pain was not different in the two groups after tourniquet release." | 2.69 | Adding clonidine to lidocaine for intravenous regional anesthesia prevents tourniquet pain. ( Bernard, JM; Bonnet, F; Gentili, M, 1999) |
| "Various minimally invasive approaches to reduce pain during extracorporeal shock wave lithotripsy (ESWL) have been described." | 2.69 | Petroleum jelly is an ideal contact medium for pain reduction and successful treatment with extracorporeal shock wave lithotripsy. ( Becker, AJ; Jonas, U; Machtens, S; Oelke, M; Stief, CG; Truss, MC, 1999) |
| " The authors conclude that EMLA is safe but not efficacious for relieving pain from heel lance in preterm infants." | 2.69 | Management of pain from heel lance with lidocaine-prilocaine (EMLA) cream: is it safe and efficacious in preterm infants? ( Aranda, J; Jack, A; Johnston, C; Koren, G; Narciso, J; Stevens, B; Stremler, R; Taddio, A, 1999) |
| "Pain was assessed by determination of heart rate, respiratory rate, and behavioral distress scoring." | 2.69 | A randomized, controlled trial of a eutectic mixture of local anesthetic cream (lidocaine and prilocaine) versus penile nerve block for pain relief during circumcision. ( deBlieck, E; Fortune, K; Generelli, P; Howard, CR; Howard, FM; tenHoopen, C; Zolnoun, D, 1999) |
| "Resultant pain was scored by a visual analogue scale (VAS), and skin temperature change was analyzed by means of a computer-assisted infrared thermography." | 2.69 | Computer-assisted infrared thermographic study of axon reflex induced by intradermal melittin. ( Dan, K; Hirata, K; Hori, K; Koyama, N; Yokota, T, 2000) |
| "Pain was assessed on a 10 cm visual analog scale (0, absence of pain; 10, greatest imaginable pain)." | 2.69 | [Use of the anesthetic cream EMLA in arterial punction]. ( Belda, J; Casan, P; Giner, J; Litvan, H; Sanchis, J, 2000) |
| "Lidocaine (1." | 2.69 | Comparison of 4 analgesic agents for venipuncture. ( Fedele, KA; Hackman, CM; Hussa, AA; Patterson, P; Vegh, GL, 2000) |
| "Prilocaine results in a lower incidence of transient neurological symptoms than lidocaine intrathecally and therefore it is more suitable for short surgical procedures." | 2.69 | The incidence of transient neurological symptoms after spinal anaesthesia with lidocaine compared to prilocaine. ( de Weert, K; Dirksen, R; Gielen, M; Slappendel, R; Traksel, M; Weber, E, 2000) |
| "Pain was assessed subjectively by asking the patients to score their pain from 0 (no pain) to 10 (most severe pain imaginable)." | 2.68 | Warming lignocaine reduces the pain of injection during peribulbar local anaesthesia for cataract surgery. ( Bell, RW; Butt, ZA, 1995) |
| "Leg and/or back pain is associated with the intrathecal use of hyperbaric 5% lignocaine." | 2.68 | Leg and back pain after spinal anaesthesia involving hyperbaric 5% lignocaine. ( Aromaa, U; Cozanitis, DA; Salmela, L, 1996) |
| " The authors conclude that the lidocaine patches used in this study are effective and safe in reducing needle insertion pain in adults." | 2.68 | Analgesic efficacy and safety of an intraoral lidocaine patch. ( Cooper, SA; Feldman, RS; Hersh, EV; Houpt, MI; Levin, LM; Wolff, MS, 1996) |
| "Pain was assessed subjectively by the use of a linear analogue pain scale ranging from 0 to 100." | 2.68 | Warming lignocaine reduces the pain of injection during local anaesthetic eyelid surgery. ( Bell, RW; Butt, ZA; Gardner, RF, 1996) |
| "Lidocaine caused an increase in all CPTs at the umbilicus and the knee reaching a statistical significance at 5 Hz for the umbilicus only." | 2.68 | Quantitative assessment of differential sensory blockade after lumbar epidural lidocaine. ( Irving, G; Tay, B; Wallace, MS, 1997) |
| "Pain was analyzed in patients with fibromyalgia (FM) in a randomized, double blind, crossover study using intravenous (i." | 2.68 | Fibromyalgia--are there different mechanisms in the processing of pain? A double blind crossover comparison of analgesic drugs. ( Ahlner, J; Bengtsson, A; Bengtsson, M; Ekselius, L; Henriksson, KG; Sörensen, J, 1997) |
| "Children with chronic renal failure are frequently exposed to painful invasive procedures." | 2.68 | Topical anaesthesia in haemodialysis: evaluation of topical anaesthesia with lidocaine during vascular access in children undergoing long-term haemodialysis for chronic renal failure. ( Ay, N; Kavukçu, S; Sersan, R; Sevinç, N; Soylu, A; Türkmen, M, 1997) |
| "Pain was scored on a visual analogue scale (0 to 100)." | 2.68 | Isometric abduction muscle activation in patients with rotator tendinosis of the shoulder. ( Brox, JI; Røe, C; Saugen, E; Vøllestad, NK, 1997) |
| "Adhesive capsulitis is a problem for the orthopedic surgeon due to the difficulty of treatment." | 2.68 | [Combined treatment for adhesive capsulitis of the shoulder]. ( Atar, D; Levy, O; Rath, E, 1997) |
| "Pain was assessed using a visual analogue scale, a verbal descriptive scale and a direct comparison between paired treatments." | 2.67 | Pain after subcutaneous injection of recombinant human erythropoietin: does Emla cream help? ( Coulthard, MG; Hardy, SP; Hughes, C; Matthews, JN; Morris, KP, 1994) |
| "Less pain was also reported during surgery (P < 0." | 2.67 | Addition of atracurium to lidocaine for intravenous regional anaesthesia. ( Elhakim, M; Sadek, RA, 1994) |
| "Tourniquet cuff pain is a significant cause of morbidity following regional anaesthesia of the upper limb." | 2.67 | The "mini-Bier's block": a new technique for prevention of tourniquet pain during axillary brachial plexus anaesthesia. ( Fell, RH; James, NK; Khoo, CT, 1994) |
| "Procedure-related pain is a significant problem for many children receiving cytotoxic chemotherapy." | 2.67 | Trial of a topically administered local anesthetic (EMLA cream) for pain relief during central venous port accesses in children with cancer. ( Arnold, M; Betcher, DL; Dose, AM; Goh, TS; Loprinzi, CL; MacKellar, DJ; Miser, AW; Niedringhaus, RD; O'Fallon, JR; Simmons, P, 1994) |
| "Pain was measured with a 100 mm visual analog scale (VAS)." | 2.67 | A double-blind placebo controlled study of a 5% lidocaine/prilocaine cream (EMLA) for topical anesthesia during thermolysis. ( Argo, LF; Flores, CA; Wagner, RF, 1994) |
| "Pain was assessed by means of a modified visual analogue scale ranging from 0 (no pain) to 10 (excruciating pain) in 25 consecutive patients (average age 65 years) undergoing bilateral eyelid surgery." | 2.67 | Effect of a topical anesthetic cream (EMLA) in reducing pain caused by infiltration of local anesthetic in eyelid surgery. ( Codère, F; Degnan, N; Sloan, J; Tucker, N, 1993) |
| "Topical application of a 30% lidocaine cream as used in this study may be a safe and efficacious anesthetic for circumcision." | 2.67 | Safety and efficacy of a topical anesthetic for neonatal circumcision. ( Claflin, KS; Erenberg, A; Jackson, EM; Leff, RD; Rasmussen, LB; Weatherstone, KB, 1993) |
| "Subjects scored the intensity of headache and nausea on separate visual analogue scales before the injection and at 10 and 20 min after injection." | 2.67 | Is intravenous lidocaine clinically effective in acute migraine? ( Fatovich, DM; Prentice, DA; Reutens, DC; Stewart-Wynne, EG, 1991) |
| "Pain was assessed according to a verbal rating scale and on a 100 mm visual analogue scale." | 2.67 | Pain control in the surgical debridement of leg ulcers by the use of a topical lidocaine--prilocaine cream, EMLA. ( Andrén, B; Grafford, K; Holm, J, 1990) |
| "Pain was recorded on a visual analogue scale by the patient and on a 3-level scale by the physician." | 2.67 | A controlled study of low and high volume anesthetic jelly as a lubricant and pain reliever during cystoscopy. ( Brekkan, E; Ehrnebo, M; Malmström, PU; Norlén, BJ; Wirbrant, A, 1991) |
| "Reported pain was significantly less after only 5 minutes of the lignocaine-prilocaine cream (p = 0." | 2.67 | Relief of injection pain in adults. EMLA cream for 5 minutes before venepuncture. ( Nott, MR; Peacock, JL, 1990) |
| "In 10 cancer patients with cutaneous allodynia, intravenous lidocaine (5 mg/kg body weight) or 0." | 2.66 | Trial of intravenous lidocaine on painful neuropathy in cancer patients. ( Banning, AM; Ellemann, K; Geertsen, P; Jensen, TS; Sjögren, P; Smith, T, 1989) |
| "Three of 4 patients with accompanying phantom limb pain noted an increase in pain after the injection of gallamine." | 2.66 | Pain responses to perineuromal injection of normal saline, gallamine, and lidocaine in humans. ( Burchiel, KJ; Chabal, C; Jacobson, L; Russell, LC, 1989) |
| "Dercum's disease (adiposis dolorosa) is associated with very painful subcutaneous fatty deposits normally localized to the lower extremities in which pain treatment is usually unsuccessful." | 2.66 | Dercum's disease (adiposis dolorosa). Treatment of the severe pain with intravenous lidocaine. ( Kastrup, J; Petersen, P, 1987) |
| "Pain was evaluated using a three-graded verbal rating scale." | 2.66 | A lignocaine-prilocaine cream reduces venipuncture pain. ( Möller, C, 1985) |
| "Pain was registered on a 10-cm visual analogue scale." | 2.66 | Clinical study of a lignocaine-prilocaine cream to relieve the pain of venepuncture. ( Carlsson, P; Hallén, B; Uppfeldt, A, 1985) |
| " The mean peak plasma concentration, time to attain the peak, area under the plasma curve from time zero to infinity, and elimination half-life were 45 micrograms/ml, 2." | 2.65 | Pharmacokinetics and tolerance of ceftriaxone in humans after single-dose intramuscular administration in water and lidocaine diluents. ( Konikoff, J; Parsonnet, M; Patel, IH; Weinfeld, RE, 1982) |
| "The two approaches were equally successful with respect to catheter insertion and analgesia and had a similar incidence of complications, although the paramedian approach caused patients more discomfort." | 2.65 | Forum. A comparison between the midline and paramedian approaches to the extradural space. ( Griffin, RM; Scott, RP, 1984) |
| "Neuro-Demoplas was compared in a double blind trial on behalf of its analgesic properties to another antiphologistic containing high dosage of vitamin B complex and Metamizol." | 2.64 | [Analgesic effect of Neuro-Demoplas in a double-blind test]. ( Gabka, J, 1976) |
| "Mechanistic approaches and multimodal analgesic techniques have been clearly demonstrated to be the most effective pain management strategy to improve outcomes." | 2.55 | Analgesia in the surgical intensive care unit. ( Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S, 2017) |
| "Currently, approaches to analgesia can be categorised in two broad categories - non-pharmacological and pharmacological agents." | 2.47 | Analgesia for amniocentesis or chorionic villus sampling. ( Alfirevic, Z; Mujezinovic, F, 2011) |
| "Inclusion was limited to: (1) randomized controlled trials in patients requiring non-complex routine dental treatments; (2) interventions comparing 4% articaine (1:100,000 epinephrine) with 2% lignocaine (1:100,000 epinephrine) for maxillary and mandibular infiltrations and block anaesthesia; and (3) with principal outcome measures of anaesthetic success, post-injection adverse events or post-injection pain." | 2.46 | The efficacy and safety of articaine versus lignocaine in dental treatments: a meta-analysis. ( Katyal, V, 2010) |
| "Enhanced somatic pains are accompanied by mechanical hyperalgesia and allodynia in FM patients as compared with healthy controls." | 2.46 | Is it all central sensitization? Role of peripheral tissue nociception in chronic musculoskeletal pain. ( Staud, R, 2010) |
| "Chronic pain is now viewed as a biopsychosocial phenomenon, in which biological, psychological, and social factors are at work." | 2.44 | Practical management strategies for the chronic pain patient. ( Forde, G; Stanos, S, 2007) |
| "Lidocaine has been used for spinal anesthesia since 1948, seemingly without causing concern." | 2.43 | Transient neurologic symptoms after spinal anesthesia with lidocaine versus other local anesthetics: a systematic review of randomized, controlled trials. ( Christiansen, C; Pace, NL; Punjasawadwong, Y; Zaric, D, 2005) |
| "Pain was defined as either persistent pain or pain at dressing changes or debridement." | 2.42 | Topical agents or dressings for pain in venous leg ulcers. ( Briggs, M; Nelson, EA, 2003) |
| "Neuropathic pain has long been recognised as one of the more difficult types of pain to treat; however, with the current emphasis on providing a multidisciplinary assessment and approach to management, more patients will be offered relief of their symptoms and an improved quality of life." | 2.41 | Management strategies for the treatment of neuropathic pain in the elderly. ( Ahmad, M; Goucke, CR, 2002) |
| "Pain was defined as either persistent pain or pain at dressing changes or debridement." | 2.41 | Topical agents or dressings for pain in venous leg ulcers. ( Briggs, M; Nelson, EA, 2000) |
| "Neuropathic pain is associated with abnormal tactile and thermal responses that may be extraterritorial to the injured nerve." | 2.41 | Spinal and supraspinal mechanisms of neuropathic pain. ( Lai, J; Malan, TP; Ossipov, MH; Porreca, F, 2000) |
| "If untreated, the pain of circumcision causes both short and long term changes in infant behaviours." | 2.41 | Pain management for neonatal circumcision. ( Taddio, A, 2001) |
| " Physicians must adhere to recommendations to avoid mucous membrane contact and ensure appropriate dosing with these agents." | 2.40 | Topical anesthesia. ( Keyes, PD; Rizos, J; Tallon, JM, 1998) |
| "Apart from short-term effects, untreated pain and stressful stimuli may also have long-term effects, which may later affect their neurological development, including the reaction to pain." | 2.40 | Pain management in neonates. ( Larsson, BA, 1999) |
| "Lidocaine should not be used to treat painful mouth lesions in children until further safety data are available." | 2.39 | Lidocaine overdose: another preventable case? ( Druckenbrod, RW; Gonzalez del Rey, J; Wason, S, 1994) |
| "Intravesical instillation of TRG-100 was found to be safe and efficient in reducing pain and irritative bladder symptoms in our study population." | 1.91 | Open Label, Pilot Evaluation of the Safety and Efficacy of Intravesical Sustained Release System of Lidocaine and Oxybutynin (TRG-100) for Patients With Interstitial Cystitis/Bladder Pain Syndrome, Overactive Bladder and Patients With Retained Ureteral St ( Ala-Adin, N; Chertin, B; Dothan, D; Gordon, A; Hatumi, S; Kafka, I; Malchi, N; Moldwin, R; Nassar, T; Perez, D; Raisin, G; Shenfeld, O; Touitou, D, 2023) |
| "The origin of pain is likely neuropathic." | 1.91 | Mpox Pain Management with Topical Agents: A Case Series. ( Bugayong, ML; DeVita, MA; Shabbir, M, 2023) |
| "Headache after subarachnoid hemorrhage and corresponding craniotomy with aneurysm clipping can be severe and difficult to treat." | 1.72 | Lidocaine Infusion for the Treatment of Headache Associated With Subarachnoid Hemorrhage: A Case Report. ( Crowley, JW; Dickerson, JR; Douangpraseuth, S; Newton, FA; Salgado, F, 2022) |
| "Considering the staggering global prevalence of local pain affecting hundreds of million individuals, it is of great significance to develop advanced dosage forms or delivery systems for analgesic therapy to fulfill clinical applicability." | 1.72 | A high-dosage microneedle for programmable lidocaine delivery and enhanced local long-lasting analgesia. ( Chen, BZ; Chu, HQ; Guo, XD; Liang, L; Zhang, BL; Zhao, ZQ; Zheng, H, 2022) |
| "The research included 40 patients with type 2 diabetes with indications of tooth extraction." | 1.72 | The changes in levels of blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction. ( Ademi Abdyli, R; Agani, Z; Ahmedi, J; Hamiti-Krasniqi, V; Prekazi Loxha, M; Rexhepi, A; Stubljar, D, 2022) |
| "Tension-type headache (TTH) is the most common type of primary headache, and trigger point injection (TPI) is frequently used for controlling pain originating from TTHs." | 1.72 | Ultrasound-guided 5-in-1 trigger point injection for treating tension-type headache: A case report. ( Chang, MC; Choo, YJ; Kim, JY, 2022) |
| "Lidocaine has a shorter time lapse (1-3 min) when used on mucus membrane; however, the effect of lidocaine for desensitization of skin has shown variable results in humans." | 1.72 | Lidocaine spray 10% prior to intravenous catheterisation in dogs. ( Haga, HA; Heggernes Softeland, M; Hoeberg, E; Lervik, A; Loken Kolstad, T; Moller, LM; Rosvold, SK, 2022) |
| "The pain was evaluated at the time of administration of the block, during the surgery, and during the postoperative period of 4 h." | 1.72 | A comparison of sub-tenon block with peribulbar block in small-incision cataract surgery. ( Antony, RM; Jeganathan, S; Kamath, AR; Rodrigues, GR, 2022) |
| " We compared the hemodynamic indexes before operation, during puncturing and at 5 minutes after operation, the pain scores during the movement of the probe in the rectum, at puncturing and at 5 minutes after surgery, and the adverse reactions to anesthesia between the two groups of patients." | 1.72 | [Application value and safety of prostate peripheral nerve block combined with dezocine in transrectal prostate biopsy]. ( Cai, QF; Lu, YX, 2022) |
| "It is clinically important to deliver a sustained-release mucoadhesive dosage of local anesthetic and antimicrobial agents for pain control." | 1.62 | Development and optimization of tibezonium iodide and lignocaine hydrochloride containing novel mucoadhesive buccal tablets: a pharmacokinetic investigation among healthy humans. ( Hanif, S; Irfan, M; Mahmood, A; Minhas, MU; Sarfraz, RM; Syed, MA, 2021) |
| "Methylene blue (MB) is a blue cationic thiazine dye and currently used in different medical settings." | 1.62 | Methylene blue induces an analgesic effect by significantly decreasing neural firing rates and improves pain behaviors in rats. ( Han, HC; Lee, SW; Moon, SW; Park, JS; Suh, HR, 2021) |
| "Pain was reported less frequently by patients who received TLA." | 1.62 | Tumescent local anesthesia versus general anesthesia for subcutaneous implantable cardioverter-defibrillator implantation. ( Alviz, I; Bello, J; Briceno, D; Della Rocca, D; Di Biase, L; Díaz, JC; Gabr, M; Grushko, M; Krumerman, A; Lakkireddy, D; Natale, A; Palma, E; Polanco, D; Purkayastha, S; Romero, J; Velasco, A; Zhang, X, 2021) |
| " Kinetic analyses of MLK infusions in cattle are necessary to establish optimal dosing protocols and withdrawal intervals." | 1.56 | Analgesic efficacy of an intravenous constant rate infusion of a morphine-lidocaine-ketamine combination in Holstein calves undergoing umbilical herniorrhaphy. ( Coetzee, JF; Hartnack, AK; Kleinhenz, MD; Lakritz, J; Niehaus, AJ, 2020) |
| "Centipede bites are a constant risk throughout tropical regions and have the rare potential for systemic side effects." | 1.51 | Challenges of Remote Medical Care in South Sudan: Centipede Bites. ( Dickson, N; Moles, I; Pallett, SJC, 2019) |
| "Conclusion: Erythermalgia may involve the face alone, and combinative approaches may be of choice for its treatment." | 1.51 | Erythermalgia Involving the Face Alone: Two Case Reports. ( Huang, YB; Liu, JH; Luo, DQ; Weng, ZS; Wu, HH; Zhao, YK, 2019) |
| " These results provide approaches to apply longer acting LA with a higher analgesic potency in an appropriate dosage and with an appropriate method of application." | 1.51 | [Pain and distress response of suckling piglets to injection and castration under local anaesthesia with procaine and licocaine - Part 2: Defence behaviour, catecholamines, coordination of movements]. ( Harlizius, J; Hofmann, K; Numberger, J; Otten, W; Rauh, A; Ritzmann, M; Scholz, T; Schulze-Horsel, T; Weiß, C; Zöls, S, 2019) |
| "Menthol inhibited phototoxicity-evoked APs and reduced pain behavior when applied topically to mice." | 1.48 | Menthol reduces phototoxicity pain in a mouse model of photodynamic therapy. ( Baptista-Hon, D; Bull, F; Dalgaty, F; Gallacher, M; Hales, TG; Ibbotson, SH; Wright, L, 2018) |
| "In total, 223 consecutive female breast cancer patients who received a TIVAP in the upper arm or chest between July 2014 and February 2016 were included." | 1.48 | A Comparison Between Upper Arm and Chest for Optimal Site of Totally Implanted Venous Access Ports in Patients with Female Breast Cancer. ( Ahn, MS; Yang, SS, 2018) |
| "The effect of AMN082 on mechanical allodynia and glutamate release was blocked by 6-(2,4-dimethylphenyl)-2-ethyl-6,7-dihydro-4(5H)-benzoxazolone (ADX71743), a selective mGluR7 negative allosteric modulator." | 1.48 | Metabotropic glutamate receptor subtype 7 in the dorsal striatum oppositely modulates pain in sham and neuropathic rats. ( Boccella, S; de Novellis, V; Farina, A; Guida, F; Iannotta, M; Luongo, L; Maione, S; Marabese, I; Palazzo, E; Serra, N, 2018) |
| " No systemic adverse event due to topical lidocaine were observed." | 1.46 | Lidocaine controls pain and allows safe wound bed preparation and debridement of digital ulcers in systemic sclerosis: a retrospective study. ( Bartoli, F; Braschi, F; Bruni, C; De Paulis, A; Fantauzzo, C; Fiori, G; Matucci-Cerinic, M; Paganelli, L; Rasero, L, 2017) |
| "More than 90% of spinal cord injuries are caused by traumatic accidents and are often associated with other tissue damage (polytrauma) that can provide a source of continued pain input during recovery." | 1.46 | Pain Input Impairs Recovery after Spinal Cord Injury: Treatment with Lidocaine. ( Aceves, M; Grau, JW; Hook, MA; Huang, YJ; Reynolds, JA; Strain, MM; Turtle, JD, 2017) |
| " Other variables included the presence of IVLI-related adverse events and the dosage and duration of IVLI." | 1.46 | Continuous Lidocaine Infusion as Adjunctive Analgesia in Intensive Care Unit Patients. ( Antigua, AD; Ebied, AM; Karras, GE; Mo, Y; Thomas, MC, 2017) |
| "Delirium is a common complication among hospitalized elderly individuals." | 1.43 | Delirium Associated With Lidocaine Patch Administration: A Case Presentation. ( Berry, KM; Byun, EK; Lee, A; Oh-Park, M, 2016) |
| "Radiation-induced oral mucositis was assessed according to the radiation therapy oncology group criteria." | 1.43 | [Effect of Kou Yan Qing Ke Li on the prevention and treatment of radiation-induced oral mucositis in patients with nasopharyngeal carcinoma]. ( Li, Z; Xudong, H; Yun, G; Zehui, F, 2016) |
| "Un total de 16 vaches Holstein ont été soumises chacune à 4 biopsies de la glande mammaire à un intervalle de 3 semaines pour un total de 64 biopsies." | 1.43 | A new technique for repeated biopsies of the mammary gland in dairy cows allotted to Latin-square design studies. ( de Lima, LS; De Marchi, FE; Dos Santos, GT; Martineau, E; Palin, MF; Petit, HV, 2016) |
| "Pain is one of the most challenging and stressful conditions to patients with sickle cell disease (SCD) and their clinicians." | 1.43 | CaMKIIα underlies spontaneous and evoked pain behaviors in Berkeley sickle cell transgenic mice. ( Chen, Y; DeSimone, J; He, Y; Lu, J; Molokie, RE; Tian, X; Wang, ZJ; Wilkie, DJ; Xiao, C; Yang, C, 2016) |
| " The potential efficacy of these MN for paediatric dosing was investigated via in vitro and in vivo studies." | 1.42 | Potential of hydrogel-forming and dissolving microneedles for use in paediatric populations. ( Caffarel-Salvador, E; Donnelly, RF; McCarthy, HO; McElnay, JC; Mooney, K; Tuan-Mahmood, TM; Woolfson, AD, 2015) |
| "Cancer-induced bone pain is described as dull, aching ongoing pain." | 1.42 | Behavioral and neurochemical analysis of ongoing bone cancer pain in rats. ( King, T; Navratilova, E; Okun, A; Porreca, F; Remeniuk, B; Sukhtankar, D; Xie, JY, 2015) |
| "FNAC-related pain is frequent and correlates with the number of nodules biopsied, age under 25 years, female sex, and anxiety." | 1.39 | Frequency and intensity of pain related to thyroid nodule fine-needle aspiration cytology. ( Azoulay, S; Baudin, E; Berdelou, A; Bidault, S; Borget, I; Chougnet, CN; Dauchy, S; Deandreis, D; Girard, E; Hartl, D; Labro, S; Laurent, S; Leboulleux, S; Lumbroso, J; Mirghani, H; Schlumberger, M; Vielh, P, 2013) |
| "Pain was assessed using a 10-point modified visual analog scale (VAS) 15 min after the biopsy procedure." | 1.38 | Size of the transrectal ultrasound probe makes no difference in pain perception during TRUS-Bx under adequate local anesthesia. ( Cevik, I; Dillioglugil, O; Koprulu, S; Unlu, N, 2012) |
| "Whether ongoing pain is present in this model is unknown." | 1.38 | Afferent drive elicits ongoing pain in a model of advanced osteoarthritis. ( Brion, T; Davis, P; Dussor, GO; King, T; Liu, P; Okun, A; Ossipov, MH; Porreca, F; Remeniuk, B; Ren, J; Xie, J, 2012) |
| " After 5 g XJ was applied to the patients, their level of lidocaine in blood was reduced to within the safe zone, and no undesirable effects were observed." | 1.38 | [Efficacy and safety of lidocaine hydrochloride jelly for the treatment of pain caused by breast cancer metastases to the skin]. ( Enomoto, T; Kikuchi, M; Kosaka, Y; Kuranami, M; Nishimiya, H; Sengoku, N; Waraya, M; Watanabe, M, 2012) |
| "Lidocaine patches are a safe, effective adjunct for rib fracture pain." | 1.37 | Lidocaine patches reduce pain in trauma patients with rib fractures. ( Mayberry, JC; Peck, EG; Schreiber, MA; Zink, KA, 2011) |
| "Deep mechanical hyperalgesia observed after RCS at -3 degrees C lasted longer ( approximately 6 weeks) and was severer than RCS at 4 degrees C." | 1.36 | Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats. ( Mizumura, K; Nasu, T; Taguchi, T, 2010) |
| "Spastic diplegia is present in three-fourths of children with cerebral palsy, interfering with gait and frequently accompanied by severe pain." | 1.36 | Coupled obturator neurotomies and lidocaine intrathecal infusion to treat bilateral adductor spasticity and drug-refractory pain. ( Andrade, P; Carrillo-Ruiz, JD; Castro, G; Godínez-Cubillos, N; Jiménez, F; Montes-Castillo, ML; Velasco, AL; Velasco, F, 2010) |
| "Diphenidol was more potent (IC(50) of 0." | 1.36 | Diphenidol inhibited sodium currents and produced spinal anesthesia. ( Chen, YC; Chen, YW; Hung, CH; Leung, YM; Wu, BT, 2010) |
| "Facial burns are quite common among children." | 1.36 | Usage of lidocaine-prilocaine cream in the treatment of postburn pain in pediatric patients. ( Kargi, E; Tekerekoğlu, B, 2010) |
| "Alleviating pain is of high importance for children undergoing chemotherapy." | 1.36 | Pain reduction in children during port-à-cath catheter puncture using local anaesthesia with EMLA™. ( Gerr, H; Grigull, L; Hoy, L; Klein, C; Leonhardt, J; Linderkamp, C; Lüllmann, B; Metzelder, M, 2010) |
| "Pain is a common feature of laminitic pathology and its management is an important component of the treatment regime for this disease." | 1.36 | In vivo priming and ex vivo activation of equine neutrophils in black walnut extract-induced equine laminitis is not attenuated by systemic lidocaine administration. ( Belknap, JK; Black, SJ; Loftus, JP; Williams, JM, 2010) |
| "Chronic pain is often a symptom after local anaesthetic-induced nerve injury." | 1.36 | Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections. ( Adey-Viscuso, D; Meechan, JG; Renton, T; Yilmaz, Z, 2010) |
| "Self-reporting of pain is considered to be the primary source of information on pain intensity for older children but a validated observational tool will provide augment information to self-reports during painful procedures." | 1.35 | The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years. ( Finnström, B; Kokinsky, E; Nilsson, S, 2008) |
| "Neuropathic pain is challenging to treat, partly because of the systemic side effects of the commonly used medications." | 1.35 | [What is the place of topical analgesia in neuropathic pain?]. ( Besson, M; Desmeules, J; Piguet, V, 2008) |
| "L3 radiculopathy was characterized by various lower limb pain and neurologic deficit." | 1.35 | Characteristics of L3 nerve root radiculopathy. ( Ebara, S; Hashidate, H; Hirabayashi, H; Kato, H; Misawa, H; Mitsui, K; Ogihara, N; Takahashi, J; Tashiro, A; Wakabayashi, S, 2009) |
| "Animals demonstrated hyperalgesia on the ipsilateral paw up to 4 days after lidocaine injection into the DRG but not after injection into the spinal nerve." | 1.35 | Lidocaine injection into the rat dorsal root ganglion causes neuroinflammation. ( Hogan, QH; Kojundzic, SL; Puljak, L; Sapunar, D, 2009) |
| "75) times and the mean oral dosage of NSAID was (1267 +/- 325) mg." | 1.35 | Continuous epidural block of the cervical vertebrae for cervicogenic headache. ( Guo, YN; He, MW; Liu, JJ; Ni, JX; Wang, Q; Yang, LQ, 2009) |
| "Although pain is the major stumbling block deterring patients and physicians from choosing this treatment option, it is not the only one." | 1.35 | What stands in the way of treating palmar hyperhidrosis as effectively as axillary hyperhidrosis with botulinum toxin type A. ( Benohanian, A, 2009) |
| " Local administration of lidocaine was shown to ablate all stimulation-induced fMRI signals by the total blockage of peripheral nerve transmission, while the analgesic effect of systemically administered lidocaine was robustly detected after intravenous infusion of approximately 3mg/kg, which is similar to clinical dosage for human." | 1.35 | fMRI investigation of the effect of local and systemic lidocaine on noxious electrical stimulation-induced activation in spinal cord. ( Abbadie, C; Cook, JJ; Hargreaves, R; Meng, X; Reicin, AS; Ritter, A; Welsh, DC; Williams, DS; Williams, M; Zhao, F, 2009) |
| "The use of botulinum toxin for the treatment of palmar hyperhidrosis is limited due to the pain associated with injections of the palm." | 1.35 | The combined use of forced cold air and topical anesthetic cream for analgesia during the treatment of palmar hyperhydrosis with botulinum toxin injections. ( Halem, M; Patel, R; Zaiac, M, 2009) |
| "Pain was evaluated with the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS), the Visual Analogue Scale (VAS) and the Face Pain Scale (FPS) for the children and with a VAS for the parents." | 1.35 | Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children. ( Blajan, V; Brochard, S; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2009) |
| "Chronic abdominal pain is a common gastrointestinal symptom experienced by patients." | 1.35 | Reversal of visceral and somatic hypersensitivity in a subset of hypersensitive rats by intracolonic lidocaine. ( Price, DD; Verne, NG; Zhou, Q, 2008) |
| " Both morphine and lidocaine retained topical activity following chronic sciatic nerve injury, but their analgesic dose-response curves were shifted to the right when compared to sham-operated mice." | 1.34 | Reorganization of dorsal root ganglion neurons following chronic sciatic nerve constriction injury: correlation with morphine and lidocaine analgesia. ( El-Maarouf Abderrahman, A; El-Maarouf, A; Kolesnikov, Y; Pasternak, G; Rutinhauser, U; Rutishauser, U, 2007) |
| "We present a case of retrobulbar hemorrhage complicating sub-Tenon's anesthesia in a patient receiving oral anticoagulants." | 1.34 | Retrobulbar hemorrhage after sub-Tenon's anesthesia. ( Best, RM; McGimpsey, S; Subbiah, S, 2007) |
| "Immunization pain is a global public health issue." | 1.34 | Routine immunization practices: use of topical anesthetics and oral analgesics. ( Ipp, M; Manley, J; Potash, L; Sgro, M; Shah, V; Taddio, A, 2007) |
| "Lidocaine was administered IV to each cat to achieve target pseudo-steady-state plasma concentrations of 0, 3, 5, 7 9, and 11 microg/mL, and isoflurane concentration was reduced to an equipotent concentration." | 1.33 | Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats. ( Ilkiw, JE; Pypendop, BH, 2005) |
| "Examination confirmed numbness and motor impairment of the lateral plantar nerve." | 1.33 | Lateral plantar nerve injury following steroid injection for plantar fasciitis. ( Dalal, R; Reading, J; Snow, DM, 2005) |
| "Chronic pain is common in patients with spinal cord injury (SCI)." | 1.33 | Pain management with interventional spine therapy in patients with spinal cord injury: a case series. ( Chiodo, A, 2005) |
| "Joint pain is a primary symptom in knee osteoarthritis (OA), but the effect of pain and pain relief on the knee joint mechanics of walking is not clear." | 1.33 | Increased joint loads during walking--a consequence of pain relief in knee osteoarthritis. ( Alkjaer, T; Bliddal, H; Danneskiold-Samsøe, B; Graven-Nielsen, T; Henriksen, M; Lund, H; Simonsen, EB, 2006) |
| "The incisional allodynia and the carrageenan-induced hyperalgesia were intensified by the microinjection of 2% lidocaine into the contralateral, but not ipsilateral APtN, the effect being significantly stronger when a large incision or a higher carrageenan concentration was utilized." | 1.32 | Involvement of the anterior pretectal nucleus in the control of persistent pain: a behavioral and c-Fos expression study in the rat. ( Del Bel, EA; Prado, WA; Villarreal, CF, 2003) |
| "Instead, referred pain is most likely a consequence of misinterpretation of the origin of input from the stimulated focal pain area, due to excitation of neurones somewhere along the neuroaxis with projected fields in the referred pain area." | 1.32 | Perceptual integration of intramuscular electrical stimulation in the focal and the referred pain area in healthy humans. ( Hansson, P; Kosek, E, 2003) |
| "Lidocaine was injected percutaneously at the sciatic nerve in volumes of 0." | 1.32 | The critical role of concentration for lidocaine block of peripheral nerve in vivo: studies of function and drug uptake in the rat. ( Birknes, J; Nakamura, T; Popitz-Bergez, F; Strichartz, GR, 2003) |
| "It is debated as to whether Achilles tendonitis (AT) has an inflammatory component." | 1.32 | Preliminary results of colour Doppler-guided intratendinous glucocorticoid injection for Achilles tendonitis in five patients. ( Bliddal, H; Koenig, MJ; Qvistgaard, E; Terslev, L; Torp-Pedersen, S, 2004) |
| "The pain was temporarily relieved by sonographically guided injection of steroid and anesthetic and was subsequently treated by surgical release of the tendon." | 1.32 | Sonographically guided injection of anesthetic for iliopsoas tendinopathy after total hip arthroplasty. ( Miller, TT; Shapiro, JF; Wank, R, 2004) |
| "Both morphine and lidocaine were active topically in the tail formalin assay, although their time-course of action appeared to be shorter than that of the formalin." | 1.32 | Evaluation of the tail formalin test in mice as a new model to assess local analgesic effects. ( Cristea, M; Kolesnikov, Y; Oksman, G; Torosjan, A; Wilson, R, 2004) |
| " The toxic reactions associated with an accidental overdose have been reported in pediatric cases." | 1.31 | Lidocaine toxicity during frequent viscous lidocaine use for painful tongue ulcer. ( Kakiuchi, Y; Miyabe, M; Sato, S; Yamaguchi, H; Yamashita, S, 2002) |
| "line is started, a cardiac monitor attached, and a urinary catheter is inserted." | 1.31 | Prostate brachytherapy under local anesthesia; lessons from the first 600 patients. ( Wallner, K, 2002) |
| "Neuropathic pain is often associated with the appearance of pain in regions not related to the injured nerve." | 1.31 | Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats. ( Bian, D; Gardell, LR; Ibrahim, M; Lai, J; Malan, TP; Ossipov, MH; Porreca, F, 2000) |
| "In untreated mice, morphine, fentanyl, clonidine, oxymetazoline, desipramine and lidocaine, but not MK801, produced dose-related antinociception when tested using a 55 degrees C water tail-flick test." | 1.31 | Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice. ( Shannon, HE; Womer, DE, 2000) |
| "Most subjects reported tooth sensitivity (recall 84." | 1.31 | Factors affecting patients' and potential patients' choices among anaesthetics for periodontal recall visits. ( Gafni, A; Matthews, DC; Rocchi, A, 2001) |
| "Tenotomy is indicated in case of recurrence, providing complete cure in 3 out of 4 cases in our series." | 1.31 | [Anterior iliopsoas impingement after total hip arthroplasty: diagnosis and conservative treatment in 9 cases]. ( Ala Eddine, T; Chantelot, C; Duquennoy, A; Giraud, F; Migaud, H; Remy, F, 2001) |
| "Clonidine was more potent in CCI then in CFA rats in reducing the response to cold." | 1.30 | The cold plate as a test of nociceptive behaviors: description and application to the study of chronic neuropathic and inflammatory pain models. ( Franssen, M; Goff, JR; Janni, G; Jasmin, L; Kohan, L, 1998) |
| "Bupivacaine was found to be superior to lidocaine in decreasing the need for postoperative narcotic analgesia." | 1.30 | The effects of local anesthetics on postoperative pain. ( McEwen, M; Roberge, CW, 1998) |
| "In fact, the nurse coached more, and trends suggested that children coped more with typical care than with EMLA." | 1.30 | Comparative study of distraction versus topical anesthesia for pediatric pain management during immunizations. ( Blount, RL; Cohen, LL; Cohen, RJ; Schaen, ER; Zaff, JF, 1999) |
| " The results of this study led us to conclude that the hematoma block with or without supplemental analgesia for the manipulation of ankle fractures was safe and effective and is a useful technique." | 1.29 | Hematoma block for ankle fractures: a safe and efficacious technique for manipulations. ( Alioto, RJ; Furia, JP; Marquardt, JD, 1995) |
| "Tolerance to inguinal hernia repair under local anesthesia was prospectively evaluated in a consecutive series of 41 patients who underwent hernia repair with local infiltration of 0." | 1.29 | Inguinal herniorrhaphy under local anesthesia: a study of intraoperative tolerance. ( Herrera, MF; Letayf, V; Prado, E, 1994) |
| " Microinjections of medetomidine into the cerebellum or the PAG produced an identical dose-response curve in the tail-flick test as that obtained following microinjection into the RVM." | 1.29 | The rostroventromedial medulla is not involved in alpha 2-adrenoceptor-mediated antinociception in the rat. ( Hämäläinen, MM; Pertovaara, A, 1993) |
| "A patient with Hodgkin's lymphoma and leiomyosarcoma in the liver developed an unusual manifestation of neuropathic pain." | 1.29 | Neuropathic pain in a cancer patient responding to subcutaneously administered lignocaine. ( Devulder, JE; Dhondt, W; Ghys, L; Rolly, G, 1993) |
| "Ischiogluteal bursitis is an easily diagnosed condition that can be effectively treated with local injection of corticosteroids." | 1.29 | Ischiogluteal bursitis in cancer patients: an infrequently recognized cause of pain. ( Baethge, BA; Mills, GM, 1993) |
| " Dogs euthanatized with pentobarbital alone had significantly longer times than did dogs euthanatized with pentobarbital in combination with any of the lidocaine concentrations." | 1.29 | Comparison of pentobarbital alone and pentobarbital in combination with lidocaine for euthanasia of dogs. ( Broadstone, R; Evans, AT; Hooks, TM; Johnston, SM; McNeil, JR; Stapleton, J, 1993) |
| "In two rabbits the myelopathy extended transversely through the white matter into the grey matter of the spinal cord." | 1.29 | Chronic catheterization of the epidural space in rabbits: a model for behavioural and histopathological studies. Examination of meptazinol neurotoxicity. ( Bille-Hansen, V; Faber, T; Jensen, FM; Madsen, JB, 1993) |
| "Two patients had cardiac arrest before sclerosis could be attempted." | 1.29 | Pericardial sclerosis as the primary management of malignant pericardial effusion and cardiac tamponade. ( Maher, EA; Shepherd, FA; Todd, TJ, 1996) |
| "Shoulder pain is a common problem in hemiplegia." | 1.28 | The source of shoulder pain in hemiplegia. ( Joynt, RL, 1992) |
| "When lidocaine was injected 0 or 10 min prior to formalin injection, a time-dependent increase in analgesia in the late phase was again observed." | 1.28 | Temporal processes of formalin pain: differential role of the cingulum bundle, fornix pathway and medial bulboreticular formation. ( Melzack, R; Vaccarino, AL, 1992) |
| "Contemporary approaches to the diagnosis and treatment of acute coronary syndromes have revolutionized the role of the nurse in the coronary care unit." | 1.27 | Nursing management of the patient with acute myocardial infarction. ( Boone, S; Del Negro, AA, 1986) |
| "SUN 1165 had no effect on clonic convulsions induced by pentetrazol and pictrotoxin in mice, while both mexiletine and lidocaine prolonged the duration of clonic convulsions." | 1.27 | General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 1st communication: effect on the central nervous system. ( Hashimoto, Y; Hatta, M; Hattori, Y; Hirotsu, I; Ishihara, T; Kihara, T; Kitakaze, Y; Miyata, T; Nakamura, S; Takahama, K, 1988) |
| "When morphine was administered with the local anesthetics, the intensity and the duration of antinociception were greater, although the time courses of the effects resembled that of morphine administered alone." | 1.27 | Local anesthetics potentiate spinal morphine antinociception. ( Akerman, B; Arweström, E; Post, C, 1988) |
| "Lidocaine has also been associated with respiratory depression, psychosis, methemoglobinemia, and toxic cardiovascular reactions." | 1.27 | Cardiopulmonary arrest due to misuse of viscous lidocaine. ( Ow, EP; Puczynski, MS; Rust, C, 1985) |
| "The occipital pain and headache of cervical arthritis also often respond to injection of 2 to 3 ml of long-acting anesthetic into the greater and lesser occipital nerves at the sites where they pierce the trapezius." | 1.26 | Relieving pain with nerve blocks. ( Carron, H, 1978) |
| "Pain was positively associated with 1) age of 15 years or less, 2) with gestation of less than 7 weeks or more than 12 and with dilatation on a curvilnear basis, and 3) with patient fear." | 1.26 | Pain of first-trimester abortion: its quantification and relations with other variables. ( Chirchirillo, L; McCarthy, MJ; Smith, GM; Stubblefield, PG, 1979) |
| "This pain is aggravated by exercise, walking downstairs and sharp bending of the knee." | 1.26 | Semimembranosus insertion syndrome: a treatable and frequent cause of persistent knee pain. ( Weiser, HI, 1979) |
| "In the present study we investigated the antiinflammatory effect of pentosanpolysulfate (SP 54) in combination with metamizol using different forms of rat paw edema (induced by dextrane, hyaluronidase, trypsin, formaldehyde, carragenine or kaolin)." | 1.26 | [Pharmacological studies on the antiphlogistic effect of pentosanpolysulfate in combination with metamizol]. ( Kalbhen, DA; Smalla, HD, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 294 (12.21) | 18.7374 |
| 1990's | 537 (22.31) | 18.2507 |
| 2000's | 734 (30.49) | 29.6817 |
| 2010's | 602 (25.01) | 24.3611 |
| 2020's | 240 (9.97) | 2.80 |
| Authors | Studies |
|---|---|
| Więckowski, K | 1 |
| Sałat, K | 1 |
| Bytnar, J | 1 |
| Bajda, M | 1 |
| Filipek, B | 1 |
| Stables, JP | 1 |
| Malawska, B | 1 |
| Vivier, D | 1 |
| Bennis, K | 1 |
| Lesage, F | 1 |
| Ducki, S | 1 |
| Gurucharan, I | 1 |
| Sekar, M | 1 |
| Balasubramanian, S | 1 |
| Narasimhan, S | 1 |
| Ghimire, B | 1 |
| Bahadur Chand, M | 1 |
| Yoo, JW | 1 |
| Koo, KC | 1 |
| Chung, BH | 1 |
| Lee, KS | 1 |
| Bromberg, H | 1 |
| Chang, Y | 1 |
| Portman, D | 1 |
| Craig, D | 1 |
| Lunoe, MM | 3 |
| Bolin, AE | 1 |
| Drendel, AL | 3 |
| Hanif, S | 1 |
| Sarfraz, RM | 1 |
| Syed, MA | 1 |
| Mahmood, A | 1 |
| Minhas, MU | 1 |
| Irfan, M | 1 |
| Menz, BD | 1 |
| Wahba, MWF | 1 |
| Slattery, P | 1 |
| Thiruvenkatarajan, V | 1 |
| Johnson, JL | 1 |
| de Roo, S | 1 |
| van Leeuwen, W | 1 |
| van der Heijden, B | 1 |
| Cicirelli, V | 1 |
| Lacalandra, GM | 1 |
| Aiudi, GG | 1 |
| Hopster, K | 1 |
| Driessen, B | 2 |
| Mitchell, CM | 1 |
| Salyards, GW | 1 |
| Theriault, BR | 1 |
| Langan, GP | 1 |
| Luchins, KR | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use Of The Needle Free Jet-Injection System With Buffered Lidocaine (J-Tip) For The Treatment Of Pain During Venipuncture For Blood Draws In Young Children[NCT01890642] | 205 participants (Actual) | Interventional | 2013-07-31 | Completed | |||
| Music as an Adjunct to Combination Analgesia for Neonatal Circumcision: A Randomized Controlled Trial[NCT04252313] | 206 participants (Anticipated) | Interventional | 2019-08-01 | Recruiting | |||
| Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures[NCT05294640] | Phase 4 | 95 participants (Actual) | Interventional | 2022-05-17 | Completed | ||
| "Clinical Study on Pain Control of Cervical Dilation by Lidocaine Solution Injected Into a Single-use Micro-non-invasive Injection Cervical Dilator"[NCT05955768] | 74 participants (Anticipated) | Interventional | 2023-07-21 | Enrolling by invitation | |||
| Oral Phenazopyridine Versus Intravesical Lidocaine for Office OnabotulinumtoxinA Analgesia: A Randomized Controlled Trial[NCT03755089] | Phase 4 | 110 participants (Anticipated) | Interventional | 2018-11-01 | Recruiting | ||
| A Sequential Allocation Study to Determine the ED50 of Dexmetedomidine as an Adjuvant to Lidocaine Intravenous Regional Anesthesia[NCT05342870] | 23 participants (Actual) | Interventional | 2012-08-31 | Completed | |||
| Assessing the Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage: a Randomized Controlled Trial[NCT03636451] | Phase 3 | 114 participants (Actual) | Interventional | 2018-10-29 | Completed | ||
| A Pragmatic Trial to Determine the Benefit of Behaviorally Enhanced Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee[NCT05035810] | Phase 3 | 240 participants (Anticipated) | Interventional | 2022-03-14 | Recruiting | ||
| Evaluation of the Efficiency of Intraligamentary + Buccal Infiltration Anesthesia and Inferior Alveolar Nerve Block + Buccal Infiltration Anesthesia in Symptomatic Mandibular Molars With Irreversible Pulpitis[NCT05839093] | 210 participants (Actual) | Interventional | 2021-12-21 | Completed | |||
| A Randomized, Controlled, Double-blinded, Within-subject (Split-face), Multicenter, Prospective Clinical Study to Compare the Level of Pain Using the Dermal Filler RHA® Redensity Formulated With Two Different Anesthetics in the Treatment of Perioral Rhyti[NCT04069585] | 30 participants (Actual) | Interventional | 2019-10-30 | Completed | |||
| Contribution of Urethral Sensory Feedback in Voiding Efficiency[NCT03637582] | 18 participants (Actual) | Interventional | 2018-11-26 | Completed | |||
| Paravertebral Block Versus Simultaneous Ketamine and Lidocaine Infusions for Pain Management in Rib Fracture Patients[NCT04413799] | Early Phase 1 | 170 participants (Anticipated) | Interventional | 2020-09-01 | Recruiting | ||
| Evaluation of the Effect of Buffered Anesthetic Solution (Lidocaine 2%) in the Effectiveness of Inferior Alveolar Nerve Block Injection During the Treatment of Mandibular Primary Molars[NCT05793905] | Phase 4 | 40 participants (Actual) | Interventional | 2022-12-01 | Completed | ||
| Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel- a Single-blinded Randomized Controlled Trial.[NCT06011005] | 42 participants (Anticipated) | Interventional | 2023-09-01 | Recruiting | |||
| Effect of Buzzy System (Vibrating Device) Compared to Topical Anaesthesia on Pain Reduction During Injection of Infiltration Anaesthesia in Children: A Randomized Clinical Trial Study.[NCT05083975] | 30 participants (Anticipated) | Interventional | 2022-07-23 | Not yet recruiting | |||
| Effectiveness of Pre Injection Use of Cryoanesthesia as Compared to Topical Anesthetic Gel in Reducing Pain Perception During Palatal Injections[NCT06165432] | Phase 4 | 60 participants (Actual) | Interventional | 2021-03-19 | Completed | ||
| A Comparison of Pain Perception Using Topical EMLA Cream Versus Lidocaine Injection for Vulvar Biopsy: a Randomized Controlled Trial[NCT03654417] | Phase 4 | 37 participants (Actual) | Interventional | 2018-09-17 | Terminated (stopped due to interim analysis produced significant results, so we ended enrollment) | ||
| Intravenous Ketorolac Administration to Attenuate Post-procedural Pain Associated With Intrauterine Device Placement: A Randomized, Double-Blind, Placebo-Controlled Trial[NCT05875571] | Phase 4 | 18 participants (Anticipated) | Interventional | 2023-09-30 | Not yet recruiting | ||
| 10% Lidocaine Spray for Pain Control During Intrauterine Device Insertion: A Randomized, Double-blinded, Placebo Controlled Trial[NCT03870711] | Phase 4 | 124 participants (Actual) | Interventional | 2018-08-01 | Completed | ||
| Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children[NCT05233683] | Phase 3 | 120 participants (Anticipated) | Interventional | 2022-03-31 | Not yet recruiting | ||
| Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized Controlled Trial[NCT03127137] | Phase 4 | 123 participants (Actual) | Interventional | 2018-08-01 | Completed | ||
| The Effect of Intravesical Lidocaine Solution Versus Placebo as Anesthesia Prior to Intravesical Injection of Onabotulinum Toxin A. A Randomized, Double-blind, Placebo Controlled Cross-over Study[NCT05415865] | Phase 3 | 50 participants (Anticipated) | Interventional | 2022-09-12 | Recruiting | ||
| Analgesic Efficacy of Intrauterine Lidocaine Flushing in Hysterosalpingo-foam Sonography: A Double-blind Randomized Controlled Trial[NCT04433611] | 150 participants (Anticipated) | Interventional | 2020-06-17 | Recruiting | |||
| Effect of Self-administered Lidocaine In-situ Gel Prior to Intrauterine Device Insertion in Women With no Previous Vaginal Delivery: A Randomized Controlled Study[NCT03166111] | Phase 3 | 216 participants (Actual) | Interventional | 2017-09-01 | Completed | ||
| Transdermal Microneedle Patch To Enhance Topical Anaesthesia Before Intravenous Line Insertion for Blood Transfusion In Paediatric Thalassemia Patients[NCT05078463] | Phase 2 | 20 participants (Actual) | Interventional | 2021-09-15 | Completed | ||
| The Use of Local Anesthetic in Intralesional Corticosteroid Injections; A Randomized, Double Blind Controlled Trial[NCT03630198] | Phase 4 | 31 participants (Actual) | Interventional | 2018-10-01 | Completed | ||
| Comparison of Ciprofol-based and Propofol-based Total Intravenous Anesthesia on Postoperative Quality of Recovery in Elderly Patients Undergoing Gastrointestinal Surgery[NCT05843383] | 280 participants (Anticipated) | Interventional | 2023-05-16 | Recruiting | |||
| 12 Versus 20 mL Paracervical Block for Pain-Control During Cervical Preparation for Dilation and Evacuation: A Single-Blinded Randomized Controlled Trial[NCT03356145] | Phase 4 | 96 participants (Actual) | Interventional | 2017-01-01 | Completed | ||
| Diaphragmatic Function, Pain Quality & Anti-inflammatory Properties: A Low Dose Dexmedetomidine Versus Ketamine in Patients With Multiple Fracture Ribs Needing Conservative Treatment[NCT04928300] | Phase 3 | 90 participants (Anticipated) | Interventional | 2021-06-12 | Recruiting | ||
| Vurdering af Perifere GABAA-receptorer Med Henblik på Lokal Smertelindring[NCT02928328] | 90 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | |||
| Efficacy of 4% Articaine Terminal Anesthesia in the Lateral Jaw Region in Children: A Double-blind Randomized Study[NCT05423392] | 60 participants (Actual) | Interventional | 2021-12-02 | Completed | |||
| Efficacy of Topical Lidocaine/Prilocaine in Pain Management in Pleurocentesis[NCT05984264] | Phase 4 | 118 participants (Anticipated) | Interventional | 2023-01-01 | Recruiting | ||
| Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.[NCT06030297] | 301 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | |||
| Comparison of Two Lidocaine Administration Techniques[NCT01330134] | Phase 4 | 481 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| High Dose Intravenous Lidocaine vs Hydromorphone for Acute Abdominal Pain in the Emergency Department: A Randomized, Comparative Efficacy Trial[NCT04398316] | Phase 4 | 187 participants (Anticipated) | Interventional | 2021-02-18 | Recruiting | ||
| Comparing Superficial vs. Deep Local Anesthetic Infiltration to Improve Patient Experience During Carpal Tunnel Release[NCT04201652] | 82 participants (Actual) | Interventional | 2019-11-27 | Completed | |||
| Randomized Controlled Trial to Compare the Outcomes Of Zone II Flexor Tendon Repair of the Hand Under General Anesthesia Versus Wide Awake Local Anesthesia No Tourniquet[NCT04089124] | 86 participants (Actual) | Interventional | 2020-02-01 | Completed | |||
| Comparison of the Efficacy and Safety of Two Homologous Active Principles for Local Dental Anesthesia: Non-inferiority Trial[NCT04166890] | Phase 4 | 179 participants (Actual) | Interventional | 2018-09-04 | Completed | ||
| Magnesium-sulfate as Adjuvant in Prehospital Femoral Nerve Block for Patient With Diaphysial Femoral Fracture: a Randomized Controlled Trial[NCT03597945] | 48 participants (Actual) | Interventional | 2015-04-30 | Completed | |||
| Vibration Anesthesia for Pain Reduction During Trigger Point Injection to the Gastrocnemius[NCT03365674] | 60 participants (Actual) | Interventional | 2017-09-30 | Completed | |||
| A Phase 1/Phase 2 Study for the Prevention of Oral Mucositis (SPOM)[NCT05338398] | Phase 1/Phase 2 | 100 participants (Anticipated) | Interventional | 2022-04-15 | Enrolling by invitation | ||
| Opioid Therapy vs Multimodal Analgesia in Head and Neck Cancer: A Randomized Clinical Trial[NCT04221165] | Phase 2 | 62 participants (Anticipated) | Interventional | 2020-08-04 | Recruiting | ||
| A Randomized Study of a New Medical Device for Oral Mucositis (MDOM Trial)[NCT05104268] | Phase 1/Phase 2 | 100 participants (Anticipated) | Interventional | 2021-11-30 | Not yet recruiting | ||
| A Phase III Placebo-Controlled, Randomized Three-Arm Study of Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy[NCT02229539] | Phase 3 | 275 participants (Actual) | Interventional | 2014-11-30 | Completed | ||
| Nebulized Lidocaine and Intranasal Midazolam for Reducing Pain/Anxiety of Nasogastric Tube Insertion in Children: A Randomized Clinical Trial[NCT04571879] | Phase 3 | 48 participants (Anticipated) | Interventional | 2021-08-25 | Recruiting | ||
| The Effect of Virtual Reality Glasses and Distraction Cards on Women's Pain, Anxiety and Satisfaction Level in Intrauterine Device Application'[NCT05655052] | 37 participants (Anticipated) | Interventional | 2022-11-15 | Recruiting | |||
| Which Combination of Local Anesthesia is Superior for Postoperative Pain After Carpal Tunnel Surgery?: A Prospective Randomized Study.[NCT05697276] | 82 participants (Actual) | Interventional | 2022-09-13 | Completed | |||
| A Double Blinded Randomized Placebo Controlled Study Evaluating the Use of Intraoperative Dexmedetomidine in Reducing Postoperative Pain and Narcotic Requirement in Patients With Moderate to Severe OSA.[NCT03613558] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2014-07-31 | Withdrawn (stopped due to Unable to recruit patients because the surgeon left the hospital) | ||
| Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia With Isobaric Bupivacaine in Patients Undergoing Surgery to Treat Skin and Soft Tissue Tumors of the Lower Limbs[NCT04741880] | Phase 2/Phase 3 | 66 participants (Anticipated) | Interventional | 2021-06-17 | Recruiting | ||
| Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery (IGNITE-AIS Study)[NCT04931433] | Phase 4 | 102 participants (Anticipated) | Interventional | 2020-12-24 | Recruiting | ||
| The Effect of Perioperative Intravenous Lidocaine Infusion on Opioid Consumption After Lumbar Spine Surgery[NCT03624985] | Phase 4 | 61 participants (Actual) | Interventional | 2018-06-04 | Terminated (stopped due to Subjects had a high dropout rate. Of 61 consented, 24 did not participate. Reasons: Surgical cancellations; changing procedure type after consent; and staffing issues. The dropout rate of 39% was considered a barrier to publication.) | ||
| Brain Imaging and Pain: Analysis of Placebo Analgesia[NCT01409538] | Phase 1 | 140 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| Buffered Lidocaine for Paracervical Block to Decrease Injection Pain During First Trimester Uterine Aspirations[NCT03107754] | Phase 4 | 98 participants (Actual) | Interventional | 2017-05-15 | Completed | ||
| Buffered vs Unbuffered Local Anesthesia Using Lidocaine, Carbocaine, and Articaine in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis[NCT06047366] | Phase 4 | 60 participants (Anticipated) | Interventional | 2023-12-05 | Recruiting | ||
| Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis: A Controlled, Randomized Double-blind Study[NCT05227300] | Phase 4 | 40 participants (Anticipated) | Interventional | 2022-02-14 | Recruiting | ||
| Comparison of 2 Application Techniques for LET (Lidocaine 4%; Epinephrine 0.1%; Tetracaine 0.5%) Gel Used Prior to Simple Laceration Repair[NCT04536493] | Phase 4 | 48 participants (Actual) | Interventional | 2019-06-19 | Completed | ||
| Lidocaine Spray Compared With Submucosal Injection in Reducing Pain During Loop Electrosurgical Excision Procedure: a Randomized Controlled Trial[NCT01505920] | Phase 3 | 101 participants (Actual) | Interventional | 2011-09-30 | Completed | ||
| The Impact of a Music Intervention on Pain and Anxiety Associated With Local Anesthesia Administration During Dermatologic Procedures[NCT04317170] | 100 participants (Actual) | Interventional | 2019-03-21 | Completed | |||
| A Randomized Controlled Trial Evaluating Three Non-invasive Analgesic Techniques in Pain Prevention During Injections[NCT03974633] | Phase 4 | 100 participants (Actual) | Interventional | 2018-02-24 | Completed | ||
| A Randomized Controlled Trial of 2% Lidocaine Gel for IUD Insertion[NCT01292447] | 150 participants (Actual) | Interventional | 2011-02-28 | Completed | |||
| Effect of Adding Vaginal Isosorbide Mononitrate to Misoprostol Prior to Intrauterine Device Insertion in Women Delivered Only by Elective Cesarean Section: a Randomized Double-blind Controlled Clinical Trial[NCT03587077] | 113 participants (Anticipated) | Interventional | 2018-09-30 | Not yet recruiting | |||
| The Influence of Vasopressin on Observational Learning of Placebo Analgesia[NCT03446456] | Phase 1/Phase 2 | 40 participants (Actual) | Interventional | 2018-09-17 | Terminated (stopped due to Due to COVID-19,) | ||
| "Do NSAIDS or Executing Exercise Decrease Local Erythema, Site Swelling & Pain After INoculation: the NEED LESS PAIN Study"[NCT02807623] | 300 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| Pain Perception of Children and Youth Receiving Non-sedated Botulinum Toxin-A Injections Using the Buzzy®[NCT02273284] | 50 participants (Anticipated) | Interventional | 2014-12-31 | Recruiting | |||
| Pain Perception Associated With Administration of Buffered Lidocaine Versus Conventional Lidocaine in the Pediatric Dental Patient[NCT04055116] | Phase 4 | 64 participants (Actual) | Interventional | 2019-11-11 | Completed | ||
| The Effect of Intracervical Lidocaine Versus Intramuscular Diclofenac for Pain Relief During Hysterosalpingography Among Infertile Women In A Tertiary Hospital In Kano: A Randomized Controlled Trial[NCT02918812] | Phase 4 | 140 participants (Anticipated) | Interventional | 2016-09-30 | Recruiting | ||
| [NCT01947205] | 111 participants (Actual) | Interventional | 2012-11-30 | Completed | |||
| The Effect of Combined Oral and Topical Analgesics to Reduce Pain Perception During Electromyography in Pediatric Population-A Randomized Controlled Trial[NCT04337814] | 113 participants (Actual) | Interventional | 2019-12-30 | Completed | |||
| Is Mathematical Arterialized Peripheral Venous Blood Gas Reliable Compared to Arterial Blood Gas? - a Clinical Validation Study[NCT03309410] | 30 participants (Actual) | Observational | 2015-09-01 | Completed | |||
| Comparison of Large Antecubital Vein Versus Small Vein on Dorsum of Hand for the Prevention of Propofol Injection Pain[NCT04673500] | 160 participants (Actual) | Interventional | 2013-05-31 | Completed | |||
| Double-blind, Randomized, Placebo-controlled Study on the Effect of Multimodal Analgesia on Pain With Insertion of Levonorgestrel-releasing Intrauterine System[NCT02799641] | 61 participants (Actual) | Interventional | 2016-07-31 | Completed | |||
| A Randomized Trial of Intranasal Fentanyl Versus Placebo as an Adjunct to Lidocaine Infiltration in Adults Undergoing Abscess Incision and Drainage in the Emergency[NCT03872700] | Phase 3 | 49 participants (Actual) | Interventional | 2019-08-01 | Completed | ||
| Using Inflammatory Biomarkers and EMG Results to Predict Epidural Injection Response in Patients Diagnosed With Lumbar Stenosis[NCT03511053] | 11 participants (Actual) | Interventional | 2017-12-19 | Completed | |||
| Multicenter Randomized Controlled Trial of Epidural Steroid Injections for Spinal Stenosis in Persons 50 and Older[NCT01238536] | Phase 4 | 400 participants (Actual) | Interventional | 2011-04-30 | Completed | ||
| Ultrasound Guided Supracondylar Nerve Block & Hematoma Block for Closed Reduction of Distal End Radius Fractures - an Observational Study[NCT05996315] | 40 participants (Anticipated) | Observational | 2022-09-15 | Recruiting | |||
| Efficacy of External Cold and a Vibrating Device in Reducing Discomfort of Dental Injections in Children - A Split Mouth Randomized Clinical Trial[NCT02675387] | 60 participants (Anticipated) | Interventional | 2015-10-31 | Recruiting | |||
| Addition of Buprenorphine to Paracervical Block Prior to Osmotic Dilator Insertion for Dilation and Evacuation: A Randomized Controlled Trial[NCT04254081] | Phase 4 | 57 participants (Actual) | Interventional | 2020-05-28 | Completed | ||
| Paracervical Block for Pain Associated With Laminaria Insertion[NCT02454296] | 41 participants (Actual) | Interventional | 2015-05-31 | Completed | |||
| Oral Sedation During Cervical Dilator Placement: A Randomized Controlled Trial[NCT03202550] | Phase 4 | 27 participants (Actual) | Interventional | 2017-06-28 | Completed | ||
| Gabapentin for Pain Control After Osmotic Dilator Insertion and Prior to D&E Procedure: a Randomized Controlled Trial[NCT03080493] | Phase 4 | 121 participants (Actual) | Interventional | 2017-03-20 | Completed | ||
| Use of Nitrous Oxide for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Second Trimester Dilatation and Evacuation[NCT05579288] | Early Phase 1 | 60 participants (Anticipated) | Interventional | 2022-12-31 | Not yet recruiting | ||
| Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During Cervical Dilator Placement Prior to Dilation and Evacuation: A Randomized Controlled Trial[NCT03868787] | 74 participants (Actual) | Interventional | 2019-05-01 | Completed | |||
| Intrauterine Lidocaine for Pain Control During Laminaria Insertion Prior to Dilation & Evacuation (D&E)[NCT01541293] | Phase 1 | 72 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| Treatment of Acral Vitiligo : Narrowband Ultraviolet-B and Microneedling With and Without Platelet Rich Plasma[NCT03155698] | 50 participants (Anticipated) | Interventional | 2021-08-31 | Not yet recruiting | |||
| Effect of Injectable Intracervical Anesthesia on the Pain Associated With the Insertion of the Levonorgestrel-releasing Intrauterine System in Women Without Previous Vaginal Delivery: a Randomized Controlled Trial[NCT02155166] | 100 participants (Actual) | Interventional | 2012-02-29 | Completed | |||
| Effectiveness of the Distraction Methods on Pain, Anxiety and Satisfaction During Cystoscopy[NCT02764294] | 120 participants (Actual) | Interventional | 2016-03-31 | Completed | |||
| Comparative Study of the Anaesthetic Efficacy of 4% Articaine Versus 2% Mepivacaine in Mandibular Third Molar Germectomy Using Different Anaesthetic Techniques: a Split-mouth Clinical Trial[NCT04465149] | 50 participants (Actual) | Interventional | 2018-06-30 | Completed | |||
| The Effect of Electroacupuncture (EA) on the Success of Inferior Alveolar Nerve Block (IANB) and Post-operative Pain Relief in Mandibular Molar With Symptomatic Irreversible Pulpitis (SIP) Among Malaysians: A Study Protocol for Randomized Double-Blinded C[NCT04804761] | 20 participants (Anticipated) | Interventional | 2023-01-01 | Recruiting | |||
| Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysterosalpingography Practice: a Prospective Randomized Double Blind, Placebo-controlled Clinical Trial[NCT01303614] | Phase 4 | 100 participants (Anticipated) | Interventional | 2011-04-30 | Not yet recruiting | ||
| The Effect of Music With Structured Verbal Training on Pain, Anxiety and Satisfaction During Prostate Biopsy[NCT04466202] | 100 participants (Actual) | Interventional | 2020-01-22 | Completed | |||
| [NCT02020551] | 223 participants (Actual) | Interventional | 2013-05-31 | Completed | |||
| Lidocaine for Pain Control During Intrauterine Device Insertion: A Randomized Clinical Trial[NCT03362905] | Phase 4 | 123 participants (Anticipated) | Interventional | 2017-12-03 | Not yet recruiting | ||
| Lidocaine Spray 10% Versus Oral Ibuprofen Tablets in Pain Control During Copper Intrauterine Device Insertion (A Randomized Controlled Trial)[NCT05241496] | 1 participants (Anticipated) | Interventional | 2021-12-15 | Recruiting | |||
| A Study Evaluating Blended Belotero for the Treatment of Etched-in Fine Facial Lines[NCT02626598] | 30 participants (Anticipated) | Observational [Patient Registry] | 2015-12-31 | Enrolling by invitation | |||
| A Randomized Clinical Trial of Buzzy Versus Vapocoolant in Pain Relief During Phlebotomy and IV Catheterization in the Pediatric ED[NCT06182631] | Phase 3 | 176 participants (Actual) | Interventional | 2019-07-15 | Completed | ||
| A Randomized, Comparison Study of L.M.X.4 Cream Versus J-Tip Needle-Free Injection System With Lidocaine in Children Undergoing In-Office Percutaneous Achilles Tenotomy for Clubfoot[NCT04766684] | Phase 4 | 94 participants (Anticipated) | Interventional | 2021-06-01 | Recruiting | ||
| A Phase III, Randomized, Double-Blind, Placebo-Controlled Study to Confirm the Effectiveness and Safety of ALGRX 3268 in Pediatric Subjects.[NCT00140088] | Phase 3 | 504 participants | Interventional | 2004-12-31 | Completed | ||
| Does LI4 Acupuncture Provide an Effective Analgesia During Intrauterine Device[NCT04963582] | 72 participants (Actual) | Interventional | 2021-07-05 | Completed | |||
| Evaluation of a Preoperative Nerve Block in Pain Scores Following Rhinoplasty/Septoplasty[NCT03780478] | Phase 1/Phase 2 | 70 participants (Anticipated) | Interventional | 2019-06-17 | Enrolling by invitation | ||
| The Influence of Injection Speed on Pain During Administration of Local Anaesthetic.[NCT02107742] | 36 participants (Actual) | Interventional | 2014-02-28 | Completed | |||
| A Randomized Blinded Controlled Trial of 2% Lidocaine Gel Compared to Standard of Care in Children Undergoing Urethral Catheterization[NCT01690767] | Phase 2 | 133 participants (Actual) | Interventional | 2011-12-31 | Completed | ||
| Preventive Application Of Lidocaine Patch In Adjunction To Intravenous Morphine Analgesia For Management Of Post-Thoracotomy Pain: Results Of A Randomized, Double Blind, Placebo Controlled Study[NCT02751619] | 90 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
| [NCT01993589] | 144 participants (Actual) | Interventional | 2012-11-30 | Completed | |||
| Randomized Trial Evaluating Lidocaine Intravenous in the Emergency Department For Sickle Cell Crisis - RELIEF-SCC[NCT04614610] | Phase 2 | 100 participants (Anticipated) | Interventional | 2024-01-01 | Not yet recruiting | ||
| Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain of Initial Orthodontic Wire Insertion: a Randomized Controlled Trial[NCT04059172] | Early Phase 1 | 375 participants (Anticipated) | Interventional | 2019-12-10 | Recruiting | ||
| Radial Artery Blood Gas Sampling: A Randomised Controlled Trial of Lidocaine Local Anaesthesia[NCT02125565] | 43 participants (Actual) | Interventional | 2012-12-31 | Completed | |||
| Diclofenac Plus Lidocaine Gel for Pain Relief During Intrauterine Device (IUD) Insertion. A Randomized Double Blinded Placebo-controlled Study[NCT02332057] | Phase 2 | 90 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
| Will Warm Patch on the Injecting Site Decrease the Injection Pain Induced by Propofol[NCT04555980] | 120 participants (Actual) | Interventional | 2020-03-20 | Completed | |||
| Efficacy of Pain Control Following Root Canal Treatment Using Paracetamol Alone and in Combination With Three Different Non-Steroidal Anti-Inflammatory Analgesics[NCT02417337] | Phase 2 | 170 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| Effect of Preoperative, Single-dose Diclofenac Potassium on Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Double Blind Randomized Controlled Trial[NCT03341260] | Phase 2/Phase 3 | 70 participants (Actual) | Interventional | 2016-12-31 | Completed | ||
| Auricular Acupuncture as Adjunct for Pain Management During First Trimester Uterine Aspiration.[NCT03391986] | 153 participants (Actual) | Interventional | 2017-09-09 | Completed | |||
| The Influence of Lidocaine Temperature on Pain During Subcutaneous Administration[NCT02107690] | 36 participants (Actual) | Interventional | 2014-02-28 | Completed | |||
| Self-Administered Lidocaine Gel for Pain Management With First Trimester Surgical Abortion: A Randomized Controlled Trial[NCT02447029] | Phase 3 | 142 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| Self-administered Intravaginal 2% Lidocaine Gel Prior to Intrauterine Device Insertion in Nulliparous Women: a Randomized Controlled Trial[NCT01534520] | 61 participants (Actual) | Interventional | 2012-06-30 | Completed | |||
| The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic[NCT02086292] | 36 participants (Actual) | Interventional | 2014-02-28 | Completed | |||
| Effectiveness of the Painless Vaccination Protocol Versus Traditional Vaccination Methodology in Reducing Pain in Children Aged 2 Months to 14 Years. A Multicenter, Quasi-experimental (Non-randomized) Controlled Study[NCT06004258] | 495 participants (Actual) | Interventional | 2022-06-21 | Completed | |||
| The Effectiveness of Two Different Methods Applied During Heel Blood Collection on Pain Level of Healthy Term Newborns[NCT04625010] | 105 participants (Actual) | Interventional | 2016-03-01 | Completed | |||
| Efficacy and Safety of Different Doses of Vaginal Misoprostol Prior to Intra Uterine Contraceptive Device Insertion[NCT04273984] | Phase 4 | 180 participants (Actual) | Interventional | 2020-03-01 | Completed | ||
| The Effect of Cold Spray and Ice Applied During Intravenous Access on Pain and Fear in Children Aged 7-15 Years in Pediatric Emergency Unit[NCT06109298] | 96 participants (Actual) | Interventional | 2021-11-01 | Completed | |||
| A New Method for Pain Relief, Intravenous Cannulation in Pediatric Patients; A Randomized Prospective Clinical Trial.[NCT04246255] | Phase 4 | 80 participants (Actual) | Interventional | 2020-02-03 | Completed | ||
| A Randomized, Placebo-Controlled Trial to Evaluate Pain and Anxiety During Venipuncture in Pediatric Patients With or Without Pre-treatment by a Topical Anesthetic[NCT00676364] | Phase 4 | 114 participants (Actual) | Interventional | 2003-03-31 | Completed | ||
| The Study of Perioperative Intravenous Infusion of Lidocaine on Postoperative Analgesia in Patients Undergoing Single-port Thoracoscopic[NCT04043624] | Phase 4 | 80 participants (Anticipated) | Interventional | 2019-08-01 | Recruiting | ||
| Double Blind, Randomized, Prospective Trial of Impact of Pain Scores on Intrauterine Lidocaine vs Normal Saline Infusion Before IUD Placement.[NCT01311102] | Phase 4 | 40 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
| A Randomized Control Trial of Virtual Reality to Reduce Anxiety During Pediatric Cast Removal[NCT03903510] | 184 participants (Anticipated) | Interventional | 2019-05-21 | Recruiting | |||
| Topical Morphine for Analgesia in Pediatric Procedures. Clinical Trial Randomized, Double-blind, Placebo.[NCT02300194] | Phase 4 | 0 participants (Actual) | Interventional | 2014-12-31 | Withdrawn (stopped due to Withdrawn by investigators) | ||
| Randomized Controlled Trial Comparing Ultrasound-guided Pudendal Nerve Block to Ultrasound-guided Penile Nerve Block for Analgesia Following Pediatric Circumcision[NCT03914365] | 300 participants (Anticipated) | Interventional | 2019-07-01 | Active, not recruiting | |||
| Testing the Efficacy of a Vibrating, Cold Device for Pediatric IV Cannulation Pain Relief in the Emergency Department[NCT01394250] | Phase 2 | 240 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| The Evaluation of the Combination of Magnesium and Lidocaine for the Pretreatment of Pain That is Caused by the Injection of Propofol.[NCT01342510] | Phase 4 | 200 participants (Actual) | Interventional | 2011-04-30 | Completed | ||
| Does Alkalinization of Technetium-99m Sulfur Colloid Reduce Perceived Pain Levels During Non-breast Sentinel Lymphoscintigraphy?[NCT01660412] | 60 participants (Actual) | Interventional | 2012-08-01 | Completed | |||
| Evaluating the Efficacy of an Ablative Fractional Carbon Dioxide Laser on Pathologic Symptoms in Pediatric Hypertrophic Scars: a Prospective Split-scar Controlled Trial[NCT04236167] | 6 participants (Actual) | Interventional | 2020-11-01 | Terminated (stopped due to Lack of participants to enroll. Early findings not supportive of fractionated c02 laser improving scars in population studied when used alone.) | |||
| Effects of Oral Melatonin on Neurosensory Recovery Following Facial Osteotomies - A Randomised, Controlled Clinical Trial[NCT02889432] | Phase 2 | 40 participants (Anticipated) | Interventional | 2016-06-30 | Recruiting | ||
| Anorectal Application of 5% Lidocaine Cream Reduces Pain Prior to Periprostatic Nerve Block During Transrectal Ultrasound Guided Biopsy: Randomized, Prospective Controlled Study[NCT04064047] | 284 participants (Actual) | Interventional | 2016-12-31 | Completed | |||
| A Contrast of Buffered Vs. Unbuffered Lidocaine in Bone Marrow Biopsies[NCT00456872] | 49 participants (Actual) | Interventional | 2004-12-31 | Completed | |||
| A Randomized Trial of Buffered vs Nonbuffered Lidocaine With Epinephrine for Cervical Loop Excision[NCT01405768] | Phase 2 | 56 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| A Randomized Controlled Study of Compound Lidocaine Cream to Prevent Postoperative Agitation in Patients With Endotracheal Intubation for General Anesthesia[NCT02017392] | Phase 4 | 2,000 participants (Anticipated) | Interventional | 2013-12-31 | Not yet recruiting | ||
| Effect of Synera in Reducing Pain Associated With Venipuncture and Superficial Dermatologic Procedures[NCT01744197] | Phase 2 | 61 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| Efficacy of Injected Local Anesthetic vs Topical Anesthetic in Cosmetic Injectable Fillers[NCT02379221] | 49 participants (Actual) | Interventional | 2014-09-30 | Completed | |||
| Phase 2 Study of Diclofenac Suppository to Control Pain During Flexible Cystoscopy[NCT01812928] | Phase 2 | 60 participants (Actual) | Interventional | 2013-03-31 | Completed | ||
| Cystoscopy in Females: Is There a Difference Between Rigid and Flex Cystoscopy, and Does it Require Local Anasthesia?[NCT03210038] | 120 participants (Actual) | Interventional | 2017-03-01 | Completed | |||
| Vulvar Vestibulitis Trial: Desipramine-Lidocaine[NCT00276068] | 128 participants (Anticipated) | Interventional | 2002-08-31 | Completed | |||
| Is Low Level Laser Therapy (LLLT) Effective for Reducing Pain Experienced by Women With Provoked Vestibulodynia?[NCT04234542] | 28 participants (Actual) | Interventional | 2021-02-18 | Completed | |||
| Effectiveness and Cost-utility of Somatocognitive Therapy Versus Treatment as Usual for Provoked (Localized) Vestibulodynia - a Randomized Clinical Trial (ProLoVe Study)[NCT04613713] | 128 participants (Anticipated) | Interventional | 2021-01-01 | Recruiting | |||
| Lidocaine With Epinephrine vs. Bupivacaine With Epinephrine as Local Anesthetic Agents in Wide-awake Hand Surgery: an Outcome Study of Patients' Pain Perception.[NCT02315573] | 61 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Brain Activation During Accommodation to Painful Stimulation With Functional Imaging of Pain[NCT01242540] | 15 participants (Actual) | Observational | 2010-11-30 | Completed | |||
| Safety and Efficacy of Lidocaine 5% Medicated Plaster in Comparison to Systemic Treatment in Postherpetic Neuralgia and Diabetic Polyneuropathic Pain.[NCT00414349] | Phase 3 | 431 participants (Actual) | Interventional | 2006-12-31 | Completed | ||
| What Determines a Positive Outcome of Spinal Manipulation for Persistent Low Back Pain: Stiffness or Pain Sensitivity? A Randomized Trial[NCT04086667] | 132 participants (Actual) | Interventional | 2017-11-01 | Completed | |||
| Delto-Tricipital Compression Syndrome: A Randomized Treatment Comparison Trial of Dextrose Injection Versus Physical Therapy.[NCT02331069] | 80 participants (Anticipated) | Interventional | 2015-01-31 | Recruiting | |||
| Effectiveness of Neuroprolotherapy With Home Physical Therapy Against Isolated Physical Therapy for the Treatment of Patellar Chondromalacia[NCT03515720] | 50 participants (Actual) | Interventional | 2018-11-01 | Completed | |||
| Randomized Double Blind Clinical Trial on the Effect of Levobupivacaine Infiltration Versus Placebo on the Post Partum Perineal Pain in Episiotomy in Primiparous Women After Instrumental Delivery[NCT02796547] | Phase 2 | 0 participants (Actual) | Interventional | 2016-07-14 | Withdrawn (stopped due to Lack of human ressources) | ||
| Prospective Randomized Trial of Standard Versus pH-adjusted Radiocolloid for Patients Undergoing Sentinel Lymph Node Mapping and Biopsy for Breast Cancer PASSION - P Trial: Ph Adjusted Sulfur-Colloid, Sentinel Initiative ON Pain Trial[NCT00940199] | 140 participants (Actual) | Observational | 2006-08-31 | Completed | |||
| Clinical Comparison of Two Anesthetic Preparations for Intravitreal Injection[NCT01087489] | 53 participants (Actual) | Interventional | 2010-04-30 | Completed | |||
| Comparison Between 2% Lidocaine Gel and 5% Tetracaine Eye Drop as Topical Anesthesia in Phacoemulsification[NCT03143452] | 72 participants (Actual) | Interventional | 2016-12-01 | Completed | |||
| [NCT01773044] | Phase 4 | 300 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| Double Blinded Randomized Trial Between Lidocaine Jelly And Plain Aqueous Gel For Urethral Straight Catheterization And The Q-Tip Test[NCT00883103] | Phase 4 | 137 participants (Actual) | Interventional | 2007-11-30 | Completed | ||
| [NCT00653861] | 72 participants (Actual) | Interventional | 2008-04-30 | Completed | |||
| Evaluation of the Effect of the Presence Of Clowns on Pain and Anxiety Seen During Injections Botulinum Toxin in Child[NCT03149263] | 80 participants (Actual) | Observational | 2015-11-10 | Completed | |||
| Comparison Between the Effects of Lidocaine Prilocaine Cream and Lidocaine Injection on Reduction of Perineal Pain During Episiotomy and Perineum Repair in Vaginal Delivery: Randomized Control Trial[NCT05891132] | 60 participants (Anticipated) | Interventional | 2023-09-01 | Not yet recruiting | |||
| Comparison of Intubation Conditions After Induction With Propofol Associated With a Dose of Remifentanil or Sufentanil in Surgical Tooth Extraction.[NCT01910285] | Phase 4 | 70 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| Paracervical Block for Pain Control During Osmotic Dilator Placement: a Randomized Controlled Trial[NCT02354092] | 14 participants (Actual) | Interventional | 2015-04-02 | Terminated | |||
| Paracervical Block With Ketorolac and Lidocaine in First Trimester Surgical Abortions[NCT00617097] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| A Prospective Randomized Study Comparing Different Types of Local Anesthesia in Outpatient Procedural Hysteroscopy[NCT05967936] | 242 participants (Anticipated) | Interventional | 2023-09-01 | Not yet recruiting | |||
| Effectiveness of Bupivacaine With Epinephrine Injections Into the Uterosacral Ligaments for Post-operative Pain Control and the Use of Narcotic Pain Medication Following Robotic Assisted Total Hysterectomies[NCT02230735] | 0 participants (Actual) | Interventional | 2014-08-31 | Withdrawn (stopped due to Study was never started.) | |||
| Paracervical Block During Office Hysteroscopy: A Randomized Double Blind Placebo-controlled Trial[NCT00811187] | Phase 2 | 80 participants (Actual) | Interventional | 2007-03-31 | Completed | ||
| A Placebo-controlled, Double-blinded, Randomized Pilot Study of Bupivacaine Liposome Injectable Suspension (EXPAREL) for Minimally Invasive Supracervical Hysterectomies Postsurgical Analgesia[NCT03769714] | Phase 4 | 56 participants (Anticipated) | Interventional | 2018-10-01 | Recruiting | ||
| Efficacy of the Combination Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis: a Randomized Clinical Trial.[NCT02110966] | Phase 4 | 56 participants (Actual) | Interventional | 2014-04-30 | Completed | ||
| Comparison of Different Analgesic Methods for Reducing Pain From Adult Intramuscular Influenza Virus Vaccine Injection[NCT01006187] | Phase 3 | 352 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
| Childhood Immunization: Reducing Immunization Distress (RID) Using Multi-Modal Distraction[NCT01379885] | 77 participants (Actual) | Interventional | 2011-06-30 | Terminated (stopped due to Estimated sample size not achieved due to decline in number of eligible patients and difficulty recruiting and retaining research staff.) | |||
| Prospective,Randomized,Blinded, Comparative,Efficacy and Safety Trial of Vapocoolant (Pain Ease Medium Stream) for Intravenous Cannulation in Emergency Department Patients.[NCT01670487] | Phase 4 | 300 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| The Effect of Sonophoresis on Topical Anesthesia: a Clinical Trial[NCT01283490] | Phase 1 | 50 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| Dry Needling in Patients With Fibromyalgia: Analysis of Its Therapeutic Effectiveness[NCT04942444] | 120 participants (Anticipated) | Interventional | 2011-01-10 | Recruiting | |||
| Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction?[NCT03443726] | 120 participants (Actual) | Interventional | 2017-06-10 | Completed | |||
| Local Anesthetic Activity of Liposomal Formulations in Dentistry[NCT01054547] | Phase 1 | 80 participants (Actual) | Interventional | 2006-09-30 | Completed | ||
| Efficacy of Liposome Lidocaine Gel for Topical Anesthesia in the Palatal Mucosa[NCT01425840] | Phase 1 | 40 participants (Actual) | Interventional | 2008-03-31 | Completed | ||
| Buffered vs Plain Lidocaine for Local Nasal Anesthesia[NCT04583137] | Early Phase 1 | 80 participants (Anticipated) | Interventional | 2020-11-01 | Not yet recruiting | ||
| Comparison of Pain of Conventional to Buffered Local Anesthesia During Injection in Pediatric Dental Patients. A Prospective, Double-blind, Randomized, Crossover Study[NCT01622296] | Phase 4 | 20 participants (Actual) | Interventional | 2012-04-30 | Completed | ||
| A Comparison of Lidocaine, Buffered Lidocaine, and Bacteriostatic Normal Saline for Local Anesthesia Prior to Peripheral Intravenous Catheterization[NCT01759459] | Phase 4 | 150 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| Randomized Controlled Trial of the Reciprocating Procedure Device Versus the Conventional Syringe in Syringe-and-Needle Procedures[NCT00651625] | 437 participants (Actual) | Interventional | 2004-11-30 | Completed | |||
| Formulations of Liposomal Local Anesthetics for Dental Anesthesia[NCT01307969] | Phase 1 | 40 participants (Actual) | Interventional | 2007-02-28 | Completed | ||
| A Randomized Trial to Determine if Local Anesthesia Decreases Pain Perception in Women Undergoing Chorionic Villus Sampling[NCT03140293] | Early Phase 1 | 120 participants (Actual) | Interventional | 2016-09-30 | Completed | ||
| A Randomized Trial of Bladder Instillations Versus Onabotulinumtoxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome[NCT04401176] | Phase 2 | 58 participants (Actual) | Interventional | 2020-09-15 | Completed | ||
| Heparin Intraoperative Instillation for Lower Urinary Tract Symptoms After Benign Hysterectomy: A Randomized Controlled Trial[NCT03633994] | Phase 2 | 104 participants (Anticipated) | Interventional | 2018-08-20 | Recruiting | ||
| Comparing The Effectiveness of Tracing Image and Coloring for Kids-Book With Two Passive Distractions on Pain and Fear in Children During Peripheral Intravenous Cannulation: A Randomized Controlled Trial[NCT04977323] | 150 participants (Anticipated) | Interventional | 2021-07-28 | Not yet recruiting | |||
| Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid Injection[NCT04794842] | Early Phase 1 | 80 participants (Actual) | Interventional | 2021-08-01 | Active, not recruiting | ||
| Double-blind Randomized Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo, in the Outpatients Area.[NCT03676556] | Phase 3 | 46 participants (Anticipated) | Interventional | 2021-06-16 | Recruiting | ||
| Randomised, Double-blind Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo[NCT02584335] | Phase 4 | 7 participants (Actual) | Interventional | 2015-07-31 | Terminated (stopped due to Difficulties with the recruitment) | ||
| Simplified IUD Insertion Technique: A Randomized Controlled Trial[NCT02733081] | 0 participants (Actual) | Interventional | 2018-01-01 | Withdrawn (stopped due to Lack of funding) | |||
| Intracervical Two Percent Lidocaine Gel as an Analgesic During Intrauterine Device Insertion: A Randomized Controlled Trial[NCT01214161] | 200 participants (Actual) | Interventional | 2010-10-31 | Completed | |||
| Postplacental Intrauterine Device Insertion: A Mixed Methods Assessment of Women's Experience[NCT02312726] | 135 participants (Actual) | Observational | 2013-11-30 | Completed | |||
| An Evaluation of the Paracervical Block for Pain Control in First Trimester Surgical Abortion[NCT01094366] | Phase 4 | 121 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| Needle-Free Jet Injection of Lidocaine for Local Anesthesia During Lumbar Puncture: A Randomized Controlled Trial[NCT01224431] | 60 participants (Actual) | Interventional | 2009-06-30 | Completed | |||
| Needle-Free Injection of Lidocaine for Local Anesthesia Prior to Trigger Digit Injection[NCT02084706] | 60 participants (Actual) | Interventional | 2014-03-31 | Completed | |||
| Venopuncture in Pediatric Emergency Department Using Koala's Distraction Method. Randomized Clinical Trial[NCT05453305] | 220 participants (Actual) | Interventional | 2021-06-01 | Completed | |||
| Validity of Bispectral Index Monitoring During Deep Sedation for Botulinum Toxin Injection in Children With Cerebral Palsy[NCT02096549] | 22 participants (Actual) | Observational | 2014-03-31 | Completed | |||
| The Contraceptive Choice Project[NCT01986439] | 9,256 participants (Actual) | Observational | 2007-08-31 | Active, not recruiting | |||
| Study of Pain Control With Hormonal IUS Insertion (SOPHI Study)[NCT02352714] | Phase 4 | 98 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Lidocaine Analgesia For Removal Of Wound Vacuum Assisted Closure Dressings: A Randomized Double Blinded Controlled Trial[NCT01126359] | 11 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| Tetracaine (Ametop®) Compared to Placebo for Reducing Pain Associated With Intramuscular Injection of Palivizumab (Synagis®) - A Pilot Study[NCT00484393] | Phase 4 | 7 participants (Actual) | Interventional | 2007-11-30 | Completed | ||
| Fractional Carbon Dioxide Laser Assisted Delivery of Topical Anesthetics: a Randomized Controlled Pilot Study[NCT02246179] | Phase 4 | 10 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| Fractional CO2 Laser Assisted Topical Articaine Anesthesia vs. Topical EMLA Administration: a Randomized Controlled Study[NCT02548533] | Phase 4 | 3 participants (Actual) | Interventional | 2015-06-30 | Terminated (stopped due to Not enough patients eligible for recruitment.) | ||
| Comparing Two Methods of Subacromial Space Injection - A Randomised Blinded Trial[NCT03692091] | 100 participants (Anticipated) | Interventional | 2017-12-06 | Recruiting | |||
| Evaluating the Effectiveness of Topical Morphine Compared With a Routine Mouthwash in Managing Cancer Treatment-induced Mucositis in Patients With Head and Neck Cancer in Isfahan[NCT01837446] | Phase 2/Phase 3 | 30 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| Efficacy of Inhaled 50% Equimolar Nitrous Oxide/Oxygen Gas Premix (Kalinox®) as Compared to Topically Administered 5% Eutectic Mixture of Lidocaine/Prilocaine (EMLA®) in Chronic Leg Ulcer Debridement[NCT02696460] | 21 participants (Actual) | Interventional | 2010-04-30 | Completed | |||
| 19-Gauge Fine Needle Aspirate (FNA) Versus 19-Gauge Fine Needle Biopsy (FNB) Needles for Endoscopic Ultrasound Guided Liver Biopsy (EUS-LB): A Randomized Prospective Trial[NCT03408171] | 40 participants (Actual) | Interventional | 2017-10-02 | Completed | |||
| 19 Versus 22-Gauge Fine Needle Biopsy (FNB) Needles for Endoscopic Ultrasound Guided Liver Biopsy (EUS-LB): A Prospective Pilot Study[NCT02967991] | 20 participants (Actual) | Interventional | 2016-08-31 | Completed | |||
| Comparison of Pain Scores Between Endoscopic Ultrasound (EUS)-Guided Liver Biopsy and Percutaneous Liver Biopsy[NCT02947516] | 0 participants (Actual) | Interventional | 2017-01-31 | Withdrawn (stopped due to Funding n/a) | |||
| Contribution of Hypnosis in Guided Hepatic Biopsy[NCT05413174] | 70 participants (Actual) | Interventional | 2022-09-29 | Completed | |||
| Comparing Pain Relief in Early Labor: Nitrous Oxide Versus Butorphonol Study[NCT01636999] | 0 participants (Actual) | Interventional | 2012-09-30 | Withdrawn | |||
| Perioperative Intravenous Lidocaine Infusion for Patients Undergoing Laparoscopic and Open Pancreatectomies[NCT02623803] | Phase 4 | 48 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| Use of a Non-medicated Plaster in Chronic Lumbar Back Pain.[NCT04651426] | 54 participants (Actual) | Interventional | 2019-08-01 | Completed | |||
| [NCT01157247] | 88 participants (Actual) | Interventional | 2009-04-30 | Completed | |||
| A Double-Blind, Randomized Controlled Trial of Jet Injection of 1% Buffered Lidocaine Versus Topical EMLA for Local Anesthesia Before Lumbar Puncture in Children[NCT01628874] | 66 participants (Actual) | Interventional | 2012-09-30 | Terminated (stopped due to Due to low recruitment numbers, the study was terminated.) | |||
| Comparison of Ketamine Versus Co-Administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department[NCT01387139] | Phase 3 | 183 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain : A Pilot Study[NCT02217267] | Phase 3 | 29 participants (Actual) | Interventional | 2014-08-01 | Completed | ||
| Intravenous Lidocaine for Preventing Painful Oxaliplatin-induced Peripheral Neuropathy (OIPN)[NCT03254394] | Phase 1/Phase 2 | 26 participants (Actual) | Interventional | 2017-09-15 | Completed | ||
| Comparing The Effectiveness of Tracing Image and Coloring for Kids-Book With Two Active Distractions on Pain and Fear in Children During Venipuncture: A Randomized Controlled Trial[NCT04983303] | 150 participants (Anticipated) | Interventional | 2021-08-01 | Not yet recruiting | |||
| Distraction in the Emergency Using Virtual Reality for Intravenous Needs in Children to Improve Comfort (DEVINCI): A Pilot Randomized Controlled Trial[NCT03750578] | 62 participants (Actual) | Interventional | 2018-12-17 | Completed | |||
| Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573] | Phase 1 | 31 participants (Actual) | Interventional | 2004-04-30 | Completed | ||
| An Evaluation of Hydrocodone/Acetaminophen for Pain Control in First Trimester Surgical Abortion[NCT01330459] | Phase 4 | 121 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| The Efficacy of Ultrasound Guided Posterior Sacroiliac Ligament Corticosteroid Injection in Pregnancy-Related Pelvic Girdle Pain: A Randomized Controlled Trial[NCT02044991] | Phase 2 | 2 participants (Actual) | Interventional | 2013-10-24 | Terminated (stopped due to The study was halted prematurely due to poor recruitment) | ||
| Observation Study of Thoracic Dermatomes[NCT03022136] | 50 participants (Actual) | Interventional | 2017-02-01 | Completed | |||
| A Pilot Study Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision[NCT02973958] | Phase 1 | 30 participants (Actual) | Interventional | 2017-02-01 | Completed | ||
| A Randomized Control Trial Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision[NCT04646967] | Phase 2 | 100 participants (Anticipated) | Interventional | 2022-11-25 | Recruiting | ||
| A Comparison of Amethocaine Creams Versus Liposomal Lidocaine Cream as Pain Reliever Prior to Venipuncture in Children at the Paediatric Emergency Department.[NCT00353002] | 0 participants (Actual) | Interventional | 2006-07-31 | Withdrawn | |||
| Randomized Controlled Trial of IN Midazolam vs IN Dexmedetomidine vs IN Ketamine Evaluating Length of Stay After Medication Administration and Anxiolysis During Minimal Procedures in Pediatric Population in Pediatric Emergency Department[NCT05934669] | Phase 4 | 90 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| Prospective Evaluation of Topical Analgesia Using a Lidocaine/Prilocaine Cream for Laceration Repair in the Emergency Department[NCT03071601] | Phase 4 | 132 participants (Actual) | Interventional | 2017-12-01 | Completed | ||
| A Prospective, Randomized, Pilot Study of Preoperative Anti-Inflammatory Therapy for Ureteral Stent Symptoms[NCT03638999] | Early Phase 1 | 36 participants (Anticipated) | Interventional | 2018-07-31 | Recruiting | ||
| A Phase II Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Intravesical Alkalinized Lidocaine-Heparin for the Symptoms of Pelvic Pain and/or Urgency of Bladder Origin[NCT00256542] | Phase 2 | 90 participants | Interventional | 2006-01-31 | Completed | ||
| Effect of Intravesical Lidocaine on Urodynamic and Symptomatic Parameters of Interstitial Cystitis[NCT00823030] | 0 participants (Actual) | Interventional | 2009-01-31 | Withdrawn | |||
| Intravesical Alkalized Lidocaine for the Treatment of Overactive Bladder (OAB), a Randomized, Double-blinded Controlled Trial[NCT00427648] | Phase 3 | 22 participants (Actual) | Interventional | 2006-03-31 | Terminated (stopped due to funding ran out, poor accrual.) | ||
| The Efficacy of the Eutectic Mixture of Local Anesthetics (EMLA) Cream Versus the Synera Patch for Pain Reduction During Venipuncture in Children[NCT00530803] | Phase 2 | 100 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| Nasogastric Tube Insertion Using Midazolam in the Emergency Department[NCT01375634] | Phase 4 | 49 participants (Actual) | Interventional | 2011-05-31 | Completed | ||
| Efficacy of Preprocedural Diclofenac in Males Undergoing Double J Stent Removal Under Local Anesthesia[NCT02598102] | Phase 2 | 150 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| Subcutaneous Injection of Botulinum Toxin A for At--Level Back Pain in Patients With Spinal Cord Injury[NCT02736890] | Phase 2 | 8 participants (Actual) | Interventional | 2016-03-31 | Terminated (stopped due to funding not available to continue) | ||
| The EMBLA Project - An Internet-based Intervention as a Supplement to Clinical Management for Vulvodynia Patients[NCT02809612] | 52 participants (Actual) | Interventional | 2016-03-31 | Completed | |||
| Clinical Safety and Efficacy of Prototype Devices for Hair Growth Control: Task 2.4[NCT00402129] | 22 participants | Interventional | 2006-01-31 | Completed | |||
| Diclofenac Suppository As a Preemptive Analgesia in Ultrasound Guided Biopsy of Prostate: Randomized Controlled Trial[NCT01939743] | Phase 2 | 100 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| The Efficacy of Analgesic Buffering With Sodium Bicarbonate for the Pediatric Dental Patient[NCT01883232] | 0 participants (Actual) | Interventional | 2013-08-31 | Withdrawn | |||
| Anesthetic Efficacy of 4% Buffered Lidocaine in Emergency Patients With Facial Swelling.[NCT01981772] | 88 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| Effect of Buffered Lidocaine on the Success of the Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis[NCT01868776] | 100 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| Effect of Intravenous Single-bolus Lidocaine Infusion Versus Intravenous Single-bolus Magnesium Sulfate Infusion on Postoperative Pain, Emotional Status and Quality of Life in Patients Undergoing Spine Fusion Surgery[NCT04776369] | Phase 4 | 60 participants (Actual) | Interventional | 2022-05-01 | Active, not recruiting | ||
| Comparison of Pain Levels in Fusion Prostate Biopsy and Standard TRUS-Guided Biopsy[NCT03859804] | 252 participants (Actual) | Interventional | 2016-12-01 | Completed | |||
| [NCT00308841] | Phase 1 | 0 participants | Interventional | Completed | |||
| Comparison Between Ondansetron 8 mg and Lidocain 40 mg in Preventing Pain Due to Propofol Injection[NCT03134612] | Phase 2 | 104 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| Topical Analgesia Before Inhalational Anaesthesia: A Retrospective Observational Study[NCT04959409] | 500 participants (Actual) | Observational | 2020-08-01 | Completed | |||
| Systemic Absorption of Lidocaine After Ultrasound Guided Hematoma Block for Reduction of Different Types of Pediatric Distal Radius Fractures[NCT04359017] | Phase 4 | 0 participants (Actual) | Interventional | 2020-11-01 | Withdrawn (stopped due to Sponsoring staff have left institution) | ||
| Evaluation of the Analgesy Using a Local Anesthetic (Lidocaine and Prolocaine) Eutectic Mixture and/or Nitric Oxide at 50% in Oxygen (Livopan®) in Pediatric Patients That During Lumbar Puncture[NCT00808171] | Phase 4 | 52 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| Comparison of Three Different Anesthetic Approaches for Intravitreal Injections: A Prospective Randomized Trial[NCT02263690] | Phase 4 | 92 participants (Actual) | Interventional | 2014-06-30 | Completed | ||
| Comparison of Handheld Vibrator to Topical Eye Drops as Anesthesia for Intravitreal Injections[NCT03079713] | 110 participants (Actual) | Interventional | 2017-04-12 | Completed | |||
| Effect of Gluten-Free Dietary Education and Intraneural Facilitation™ on Quality of Life in People With Diabetic Neuropathy[NCT05165368] | 70 participants (Anticipated) | Interventional | 2023-08-01 | Recruiting | |||
| Optimal Dose of Combination of Rocuronium and Cisatracurium: A Randomized Double-blinded Clinical Trial[NCT02495038] | 81 participants (Actual) | Interventional | 2014-03-31 | Completed | |||
| Repetitive Transcranial Magnetic Stimulation (rTMS) for Orthopaedic Trauma Patients[NCT03924024] | 0 participants (Actual) | Interventional | 2019-08-01 | Withdrawn (stopped due to We never started the study due to logistical limitations.) | |||
| Intracervical Block and Pain Perception During the Performance of a Hysterosalpingogram: A Randomized Controlled Trial[NCT00372658] | Phase 2 | 120 participants | Interventional | 2002-07-31 | Completed | ||
| Analgesic Effect of Perioperative Systemic Lidocaine in Patients Undergoing Unilateral Mastectomy Surgery[NCT00913003] | Phase 4 | 22 participants (Actual) | Interventional | 2009-05-31 | Terminated (stopped due to PI terminated employment with the University) | ||
| Does Rapydan Influence Routine Clinical Chemistry and Hematology Measurements?[NCT00765934] | 25 participants (Anticipated) | Interventional | 2009-11-30 | Completed | |||
| Local Anesthesia for Prostate Biopsy: Effects on Pain Control, Quality of Life, and Surgical Intervention[NCT00422708] | Phase 4 | 243 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| Effective Analgesia Using the 5 S's During Routine Immunizations at 2 and 4 Months[NCT01368861] | 230 participants (Actual) | Observational | 2010-06-30 | Completed | |||
| Intravenous Sedation and Analgesia Using Propofol, Fentanyl and Ketamine (PFK) Versus General Anesthesia in Minor Urological Procedures.[NCT04285528] | 200 participants (Actual) | Interventional | 2019-04-17 | Completed | |||
| Dexmedetomidine Comme Adjuvant à la rachianesthésie Lors de césariennes électives : Une étude Pilote[NCT05099055] | Phase 3 | 42 participants (Actual) | Interventional | 2022-03-15 | Completed | ||
| Comparison of Caudal Bupivacaine Alone With Bupivacaine Plus Two Doses of Dexmedetomidine for Postoperative Analgesia in Pediatric Patients Undergoing Infra-umbilical Surgery: A Randomized Controlled Double Blinded Study[NCT02385435] | Phase 2/Phase 3 | 91 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Effects of Intra-articular Versus Subacromial Steroid Injections on Clinical Outcomes in Adhesive Capsulitis[NCT00742846] | 0 participants (Actual) | Interventional | 2008-08-31 | Withdrawn (stopped due to No enrollment) | |||
| Pain Control for Intrauterine Device Placement: A Randomized Controlled Trial of Paracervical Block[NCT02219308] | 67 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Saline Injection - Assisted Anesthesia in Eyelid Surgery[NCT01239498] | Phase 4 | 60 participants (Anticipated) | Interventional | 2010-11-30 | Recruiting | ||
| Efficacy of Hematoma Block on Postoperative Pain After Femoral Intramedullary Rodding: A Randomized Trial[NCT04860856] | Phase 4 | 88 participants (Actual) | Interventional | 2019-08-17 | Completed | ||
| "Comparison of Ultrasound-guided Hematoma Block and Blind Hematoma Block for Analgesia in Distal Radius Fractures"[NCT02346929] | 115 participants (Anticipated) | Interventional | 2014-08-31 | Recruiting | |||
| A Pilot Study Comparing Intra-articular Corticosteroid Injections to Platelet Rich Plasma (PRP) as a Treatment for Cervical Facetogenic Pain[NCT04392999] | Phase 2/Phase 3 | 55 participants (Actual) | Interventional | 2021-02-01 | Active, not recruiting | ||
| Nitrous Oxide as Treatment for Fibromyalgia[NCT05357066] | Phase 2 | 50 participants (Anticipated) | Interventional | 2021-11-12 | Recruiting | ||
| Evaluation of the Efficiency of a Therapeutic Education Program in Standardized Thermal Cure for Fibromyalgia Patients[NCT02406313] | 152 participants (Actual) | Interventional | 2015-03-31 | Active, not recruiting | |||
| THE PRISM Study-Low-Molecular-Weight Heparin Versus Unfractionated Heparin for Perioperative Bridging Anticoagulation: the Patient Preference for Self-Injection Study and Related Measurements[NCT00253396] | Phase 4 | 100 participants (Anticipated) | Interventional | 2005-10-31 | Completed | ||
| Study of the Efficiency of the Ketamine With Low Analgesic Doses, in Association With High Opioids, in the Treatment of the Rebels Pains, in Palliative Phase of the Cancerous Disease[NCT01326325] | Phase 3 | 24 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| Clinical Outcome in Subacute Stroke Patients With Hemiplegic Shoulder Pain and Rotator Cuff Injuries After Hyaluronic Acid Injection[NCT02465853] | 42 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections: a Prospective Double-Blinded Randomized Trial[NCT04895280] | Phase 4 | 400 participants (Anticipated) | Interventional | 2024-04-30 | Not yet recruiting | ||
| Treatment of Rotator Cuff Syndrome With Injection of Autologous Platelet Rich Plasma[NCT01123889] | 12 participants (Actual) | Interventional | 2010-05-31 | Completed | |||
| Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial[NCT04115644] | Phase 4 | 82 participants (Actual) | Interventional | 2017-05-01 | Terminated (stopped due to Covid-19 and we failed to submit annual report for 2017 and 2018) | ||
| Dorsal Penile Nerve Block for Rigid Cystoscopy in Men: a Single-center, Randomized, Double-blind and Placebo-controlled Study[NCT02502487] | 258 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| The Effects on Betadine 5% Penetration When Using Lidocaine 2% Jelly Versus Topical Tetracaine 0.5% for Topical Phacoemulsification Cataract Surgery.[NCT00827073] | 40 participants (Actual) | Interventional | 2008-11-30 | Completed | |||
| Evaluation of Analgesia With the Use of Eutectic Mixture of Local Anesthetics (Lidocaine and Prilocaine) and Oral Solution of Glucose to 25% in Preterm Neonates During Arterial Puncture and / or the Installation of Percutaneous Catheter[NCT00808054] | Phase 4 | 60 participants (Actual) | Interventional | 2008-11-30 | Completed | ||
| Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444] | Phase 2 | 13 participants (Actual) | Interventional | 2017-05-23 | Terminated (stopped due to Efficacy was not seen after interim analysis) | ||
| Intercostobrachial Nerve Block (ICBN) for Tourniquet Pain: Is it Necessary?[NCT03797924] | Early Phase 1 | 46 participants (Actual) | Interventional | 2019-04-25 | Completed | ||
| Optimal Lidocaine Buffering to Reduce Injection Pain in Local Anesthesia[NCT02647892] | Phase 4 | 70 participants (Actual) | Interventional | 2016-01-08 | Terminated (stopped due to IRB protocol administratively closed, Continuing Review or Study Completion Report not submitted) | ||
| Optimal Lidocaine Propofol Mixture for Painless Induction of Anesthesia[NCT05898061] | 100 participants (Anticipated) | Observational [Patient Registry] | 2023-03-01 | Recruiting | |||
| Protein Profile of Immunoregulatory Factors in Diabetic Cataract[NCT01832311] | Phase 4 | 61 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| The Effect of Shotblocker on Pain and Patient Satisfaction for Spinal Anesthesia[NCT03554122] | 88 participants (Actual) | Interventional | 2018-01-01 | Completed | |||
| Comparison of Two Analgesic Pretreatment Techniques (2% Lidocaine Infiltration vs. EMLA Cream Application) Before Spinal Needle Insertion for Pain Reduction and Maternal Satisfaction Level Assessment in Women Undergoing LSCS. A Prospective Randomized Cont[NCT04050059] | 62 participants (Actual) | Interventional | 2019-11-13 | Completed | |||
| Impact of 50% Nitrous Oxide Inhalation on Pain Induced by Lumbar Puncture in Emergency: a Double-blind Randomized Controlled Trial.[NCT03941990] | Phase 4 | 88 participants (Anticipated) | Interventional | 2019-11-27 | Recruiting | ||
| Non- Inferiority Study of Erector Spinae Plane Block Compared to Thoracic Epidural Analgesia in Multimodal Pain Management of Multiple Rib Fractures[NCT05069961] | 0 participants (Actual) | Interventional | 2023-05-31 | Withdrawn (stopped due to Study was closed with IRB as PI wants to design the protocol extensively.) | |||
| Comparison of Epidural and Paracostal Catheter Placement for Pain Control After Rib Fractures[NCT02295098] | 36 participants (Actual) | Interventional | 2015-08-19 | Completed | |||
| Effect of Intraperitoneal Bupivacaine on Postoperative Pain Control in Patients Undergoing Pelvic Organ Prolapse Repair[NCT06120530] | Phase 4 | 90 participants (Anticipated) | Interventional | 2023-08-15 | Recruiting | ||
| A 3-arm Randomized Controlled Study Comparing Ultrasound-guided Cryoablation, Ultrasound-guided Perineural Lidocaine and Ultrasound-guided Perineural Saline to Treat Intermetatarsal Neuroma[NCT02838758] | Phase 1 | 10 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| Is There Any Advantage of PRP Over Autologous Blood Injection in the Treatment of Chronic Plantar Fasciitis? A Prospective Randomized Double Blinded Study[NCT05240872] | Phase 3 | 60 participants (Actual) | Interventional | 2020-03-01 | Completed | ||
| A Study Into the Use of Prefabricated Orthotics in Shoes, in Combination With Using Indoor Comfort Sandals With built-in Arch Support vs. the Sole Use of Prefabricated Orthotics in Shoes Alone, for the Treatment of Plantar Fasciitis. A Randomised Control [NCT04894383] | 104 participants (Actual) | Interventional | 2021-07-23 | Completed | |||
| Optimizing Patient Analgesic Experience During IVF[NCT01814657] | 308 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| Randomized Controlled Trial of Transcutaneous Electrical Nerve Stimulation for Pain Relief During Transvaginal Oocyte Retrieval Using Conscious Sedation[NCT03472430] | 160 participants (Actual) | Interventional | 2018-05-04 | Completed | |||
| A Randomized Study on Use of Virtual Reality Technology for Pain Relief in Transvaginal Oocyte Retrieval Under Conscious Sedation[NCT05218382] | 160 participants (Anticipated) | Interventional | 2022-12-01 | Recruiting | |||
| Understanding Pediatric Symptoms and Other Symptoms[NCT00166231] | 156 participants (Actual) | Observational | 2004-03-31 | Completed | |||
| Safety of Intravenous Lidocaine Infusions for Chronic Neuropathic Pain[NCT01091935] | 70 participants (Actual) | Observational | 2009-06-30 | Completed | |||
| The Effect of Lidocaine to Prevent the Development of Chronic Post-Surgical Pain[NCT01619852] | 148 participants (Actual) | Interventional | 2012-06-30 | Completed | |||
| The Comparison of the Discharge Conditions and Efficacy of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl in Outpatient Minor Perianal Surgery[NCT01880775] | Phase 4 | 50 participants (Actual) | Interventional | 2012-04-30 | Completed | ||
| Venous Versus Arterial Blood Gas Sampling in Undifferentiated Emergency Patients[NCT04409470] | 250 participants (Actual) | Observational | 2021-10-11 | Completed | |||
| Analgesic Effect of Ketamine in Patients Undergoing Hysteroscopic Endometrial Thermal Ablation Surgery[NCT01106846] | 22 participants (Actual) | Interventional | 2010-03-31 | Terminated (stopped due to Resources not available to complete.) | |||
| Does Repetitive Peripheral Nerve Blocks Vs Single Peripheral Nerve Block Vs Standard Medical Treatment Provide a Better Pain Relief on Zoster Pain at the Acute Phase and Reduce the Risk of Post Herpetic Neuralgia?[NCT04133142] | 0 participants (Actual) | Interventional | 2020-05-15 | Withdrawn (stopped due to No enrollement and covid) | |||
| Single-dose Potassium Supplementation in ADHD Patients With Lidocaine Ineffectiveness[NCT03563573] | Phase 1/Phase 2 | 100 participants (Anticipated) | Interventional | 2018-07-01 | Enrolling by invitation | ||
| Prevalence of Lidocaine Ineffectiveness in Those With Hard-to-treat ADHD[NCT04167189] | Early Phase 1 | 28 participants (Actual) | Interventional | 2018-01-20 | Completed | ||
| Reliability Testing of a Non-invasive, Pain-free, Taste-based Assessment Approach to Lidocaine Effectiveness[NCT03680885] | Early Phase 1 | 20 participants (Actual) | Interventional | 2019-08-01 | Completed | ||
| Assessing the Frequency of Lidocaine Ineffectiveness in the General Population vs. Males With ADHD, and Females With ADHD, With or Without PMS[NCT03676725] | Early Phase 1 | 90 participants (Actual) | Interventional | 2019-08-14 | Completed | ||
| Double Blind Trial Investigating the Role of Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients[NCT03847311] | Phase 2 | 40 participants (Anticipated) | Interventional | 2021-05-03 | Recruiting | ||
| Toward Personalized Treatment of Chronic Pain Using Transcranial Direct Current Stimulation Paired With Deep Learning[NCT05863494] | 40 participants (Anticipated) | Interventional | 2023-06-01 | Recruiting | |||
| Cefazolin-Lidocaine Solution for Reducing Pain Associated With Subconjunctival Antibiotic Prophylaxis in Vitreo-Retinal Surgery[NCT02324166] | Phase 4 | 54 participants (Anticipated) | Interventional | 2015-01-31 | Not yet recruiting | ||
| Double-blind Trial of Mannitol Cream to Block the Effect of Capsaicin Cream[NCT01963910] | 25 participants (Actual) | Interventional | 2013-12-31 | Completed | |||
| Low Epidural Anesthesia With Chloroprocaine Versus Lidocaine: a Prospective, Randomized, Double-blinded Multi-centre Clinical Trial in China[NCT02287870] | Phase 4 | 120 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| Intra-arterial Lidocaine for Pain Control Post Uterine Fibroid Embolization : a Single-center Prospective Randomized Study[NCT02293447] | Phase 4 | 60 participants (Actual) | Interventional | 2014-11-30 | Completed | ||
| Postoperative Pain Control in Extracapsular Hip Fracture Patients: Fascia Iliaca Compartment Block Versus Fracture Block[NCT04335461] | Early Phase 1 | 0 participants (Actual) | Interventional | 2021-08-05 | Withdrawn (stopped due to Study was withdrawn. Study expired in IRB system and no patients enrolled as per institutional CTMS and IRB systems. Primary and Study Completion Dates reflect date IRB approval expired.) | ||
| Observational Study to Evaluate the Prevalence of Rotator Cuff Tears in Hemiplegic Shoulders[NCT00998868] | 51 participants (Actual) | Observational | 2008-01-31 | Completed | |||
| Pain Prevention During Propofol Infusion in Pediatric: Hypnoanalgesia of the Hand Versus Lidocaine.[NCT03453723] | Phase 4 | 100 participants (Actual) | Interventional | 2018-04-18 | Completed | ||
| Safety and Effects of PDRN(Polydeoxyribonucleotide) Injection in Patient With Elbow Epicondylitis in Randomized Double-blind Active-control Comparative Study[NCT02492945] | Phase 4 | 40 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| Treatment of Tendon Injury Using Allogenic Adipose-derived Mesenchymal Stem Cells: Phase II Double-Blind Placebo-Controlled Randomized Clinical Trials.[NCT02298023] | Phase 2 | 24 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| Treatment of Tendon Injury Using Allogenic Adipose-derived Mesenchymal Stem Cells(ALLO-ASC):A Pilot Study[NCT01856140] | Early Phase 1 | 12 participants (Actual) | Interventional | 2013-05-31 | Completed | ||
| Skin Sterility After Ethyl-Chloride Spray[NCT01292850] | 15 participants (Actual) | Observational | 2009-02-28 | Completed | |||
| Analgesia Assessment of Conversational Hypnosis Script During Peripherical Veinous Catheter Set up Versus Standard Script in Operating Room[NCT04358094] | 200 participants (Anticipated) | Interventional | 2020-05-04 | Not yet recruiting | |||
| A Randomized, Controlled Study to Evaluate the Effectiveness of Farabloc for Chronic Phantom Limb Pain Among Veteran Amputees[NCT00797849] | 57 participants (Actual) | Interventional | 2008-11-30 | Completed | |||
| Local Anaesthetic Effects of Transcutaneous Amitriptyline in Human Volunteers : a Controlled, Double-blinded, Randomised Study Versus Placebo and Transcutaneous Local Anaesthetic (EMLA(R))[NCT00355277] | Phase 1 | 16 participants | Interventional | 2005-11-30 | Completed | ||
| Subacromial Injection of High Volume Versus Conventional Steroid Injection Guided by Ultrasound in Shoulder Pain. Randomized Controlled Trial[NCT03303001] | 22 participants (Actual) | Interventional | 2017-10-10 | Completed | |||
| Double-blind, Prospective Comparison of Medications Used in Trigger Point Injections - Ketorolac, Lidocaine, or Dexamethasone[NCT03028012] | Phase 4 | 10 participants (Actual) | Interventional | 2017-05-02 | Terminated (stopped due to Poor enrollment.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Pain score assessed by video reviewer before intervention (0 minute) and at venipuncture (3 minutes). The score at baseline was subtracted from the score at venipuncture to give a number indicating the change in pain scores.~The FLACC (Face, legs, activity, cry and consolability) Scale, ranging from 0 (no pain) to 10 (worst pain), was used to assess pain." (NCT01890642)
Timeframe: 3 min
| Intervention | units on a scale (Mean) |
|---|---|
| J Tip Noise | 2.32 |
| Pain Ease | 3.7 |
| J Tip | 1.58 |
"Pain score assessed by video reviewer at J-tip, J-tip noise or researcher approach (1 minute) and at venipuncture (3 minutes). The score at J-tip noise/researcher approach was subtracted from the score at venipuncture to give a number indicating the change in pain scores.~The FLACC (Face, legs, activity, cry and consolability) Scale, ranging from 0 (no pain) to 10 (worst pain), was used to assess pain." (NCT01890642)
Timeframe: 3 min
| Intervention | units on a scale (Mean) |
|---|---|
| J Tip Noise | 1.71 |
| Pain Ease | 2.82 |
| J Tip | 0.23 |
Proportion of patients where blood draw was successful on first attempt (NCT01890642)
Timeframe: up to 3 minutes
| Intervention | participants (Number) |
|---|---|
| J Tip Noise | 52 |
| Pain Ease | 48 |
| J Tip | 86 |
Pain when J-tip deployed assessed by video reviewers using pain scale. The FLACC (Face, legs, activity, cry and consolability) Scale, ranging from 0 (no pain) to 10 (worst pain), was used to assess pain. (NCT01890642)
Timeframe: 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| J Tip Noise | 3.25 |
| Pain Ease | 2.5 |
| J Tip | 4.0 |
Pain score as assessed by video reviewers. The FLACC (Face, legs, activity, cry and consolability) Scale, ranging from 0 (no pain) to 10 (worst pain), was used to assess pain. (NCT01890642)
Timeframe: At venipuncture (3 minutes)
| Intervention | units on a scale (Median) |
|---|---|
| J Tip Noise | 5.75 |
| Pain Ease | 8 |
| J Tip | 5.25 |
Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded after the procedure reflecting the overall pain felt during the procedure. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once 10 minutes after the procedure on the day of recruitment, approximately one minute.
| Intervention | units on a scale (Median) |
|---|---|
| 20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block | 57 |
| 40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block | 56 |
Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded 10 minutes after the completion of the procedure. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once 10 minutes after the procedure on the day of recruitment, approximately one minute.
| Intervention | units on a scale (Median) |
|---|---|
| 20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block | 26 |
| 40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block | 11 |
Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded at time of cervical dilation. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once during the procedure on the day of recruitment, approximately one minute. During procedure at time of cervical dilation.
| Intervention | units on a scale (Median) |
|---|---|
| 20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block | 52 |
| 40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block | 45 |
Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded immediately after uterine aspiration. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once during the procedure on the day of recruitment, approximately 1 minute. During procedure immediately after uterine aspiration.
| Intervention | units on a scale (Median) |
|---|---|
| 20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block | 46 |
| 40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block | 58 |
"Injection pain during injection was measured on the 100 mm Visual Analog Scale (VAS), as assessed by subjects immediately after injection of each upper perioral quadrant.~VAS is a 100 mm Visual Analog Scale with 0 meaning no pain and 100 meaning intolerable pain" (NCT04069585)
Timeframe: Visit 1 - During Injection
| Intervention | mm (Mean) |
|---|---|
| RHA® Redensity With Lidocaine | 22.4 |
| RHA® Redensity With New Anesthetic Agent | 25.0 |
"Global Aesthetic Improvement (GAI) is a subjective 5-grade scale comprised of much improved, improved, no change, worse, and much worse.~GAI was assessed using the baseline photograph. Subjects were instructed as follows: Use a mirror to compare your face to the photograph provided to you and rate the degree of aesthetic improvement by using the following scale.~Each side of the face was assessed independently." (NCT04069585)
Timeframe: Visit 1 (post-injection) and Visit 2 (Day 30)
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Visit 1 (post-injection) | Visit 2 (Day 30) | |
| RHA® Redensity With Lidocaine | 30 | 30 |
| RHA® Redensity With New Anesthetic Agent | 30 | 30 |
"Global Aesthetic Improvement (GAI) is a subjective 5-grade scale comprised of much improved, improved, no change, worse, and much worse.~GAI will bewas assessed using the baseline photograph. Each side of the mouth were assessed independently." (NCT04069585)
Timeframe: Visit 1 (post-injection) and Visit 2 (Day 30)
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Visit 1 (post-injection) | Visit 2 (Day30) | |
| RHA® Redensity With Lidocaine | 30 | 30 |
| RHA® Redensity With New Anesthetic Agent | 30 | 30 |
"PR-SRS (Perioral Rhytids Severity Rating Scale) is a validated 4-grade scale with 0 being Absent and 3 being Severe" (NCT04069585)
Timeframe: Visit 1 (Baseline, pre-injection) - Visit 1 (post-injection), Visit 2 (Day 30)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Visit 1 (Post-injection) | Visit 2 (Day 30) | |
| RHA® Redensity With Lidocaine | -1.5 | -1.4 |
| RHA® Redensity With New Anesthetic Agent | -1.5 | -1.4 |
"Injection pain was measured on the 100 mm Visual Analog Scale (VAS), as assessed by subjects in each side of the mouth.~VAS is a 100 mm Visual Analog Scale with 0 meaning no pain and 100 meaning intolerable pain" (NCT04069585)
Timeframe: Visit 1 - 15, 30, 45 and 60 minutes post-injection
| Intervention | mm (Mean) | |||
|---|---|---|---|---|
| 15 Min | 30 Min | 45 Min | 60 Min | |
| RHA® Redensity With Lidocaine | 6.3 | 1.0 | 0.3 | 0.0 |
| RHA® Redensity With New Anesthetic Agent | 6.8 | 1.0 | 0.4 | 0.0 |
"The subjects will receive a diary booklet and instructions for recording his/her observations of the Common Treatment Responses to the study treatments within 30 days following the treatment. The diary will be discussed during follow-up phone-call and visit. Subjects were instructed to complete the diary at approximately the same time each day (i.e., am or pm).~The subject diary captured the following Common Treatment Responses (CTR) that occur following the injection of a dermal filler; specifically, redness, pain, tenderness, firmness, swelling, lumps/bumps, bruising, itching, discoloration, and other.~The 30-day patient CTR diary included a detailed glossary describing all signs/symptoms listed in the diary; an option was provided to report other reactions if the subject experienced a sign/symptom that was not listed." (NCT04069585)
Timeframe: During 30 days after injection
| Intervention | Participants (Count of Participants) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Bruising | Discoloration | Firmness | Itching | Lumps/Bumps | Pain | Redness | Swelling | Tenderness | Needle track marks | Injection Site Soreness | |
| RHA® Redensity With Lidocaine | 16 | 10 | 19 | 2 | 17 | 4 | 15 | 19 | 12 | 1 | 1 |
| RHA® Redensity With New Anesthetic Agent | 12 | 10 | 14 | 4 | 15 | 3 | 16 | 21 | 13 | 1 | 1 |
"The FACE-Q measures the experience and outcomes of aesthetic facial procedures from the patient's perspective.~FACE-Q questionnaire is composed of 6 questions with a score linked to answers (1 being 'Not at all' and 4 being 'Extremely').~The subject will be instructed as follows: These questions ask about how you look right now. For each question, circle only one answer. With the area around your lips in mind, in the past week, how much have you been bothered by:, and will provide response.~To calculate the FACE-Q, outcomes from all 6 questions were pooled, data were transformed so that higher scores reflected a superior outcome, and adapted to a scale of 100 units (i.e. lowest score = 0, highest score = 100)." (NCT04069585)
Timeframe: Visit 1 (Baseline) and Visit 2 (Day 30)
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| Baseline Face-Q Score | Day 30 Face-Q Score | Face-Q Change from Baseline to Day 30 | |
| RHA® Redensity With Lidocaine | 13.0 | 73.9 | 60.9 |
| RHA® Redensity With New Anesthetic Agent | 12.5 | 77.2 | 64.7 |
"The Subject Satisfaction Scale is a subjective, balanced, 5-point scale assessing subject satisfaction with study treatment. Possible scores range from with 1 (very satisfied) to 5 (very dissatisfied).~Proportion of subjects who were Satisfied (i.e., 1-Very Satisfied + 2-Satisfied) was compared to the proportion of subjects who were Not Satisfied (i.e., 3-Neither Satisfied nor dissatisfied + 4-Dissatisfied + 5-Very Dissatisfied)" (NCT04069585)
Timeframe: Visit 1 (post-injection) and Visit 2 (Day 30)
| Intervention | Participants (Count of Participants) | |||||||
|---|---|---|---|---|---|---|---|---|
| Visit 1 (post-injection)72557804 | Visit 1 (post-injection)72557805 | Visit 2 (Day 30)72557804 | Visit 2 (Day 30)72557805 | |||||
| Satisfied (i.e., 1-Very Satisfied + 2-Satisfied) | Not Satisfied (i.e., 3-Neither Satisfied nor dissa | |||||||
| RHA® Redensity With Lidocaine | 29 | |||||||
| RHA® Redensity With New Anesthetic Agent | 29 | |||||||
| RHA® Redensity With Lidocaine | 1 | |||||||
| RHA® Redensity With New Anesthetic Agent | 1 | |||||||
A responder corresponds to a subject with an intra-individual improvement of at least one grade on the PR-SRS compared to Baseline (NCT04069585)
Timeframe: Visit 1 - Baseline (pre-injection), Visit 1 (post-injection), Visit 2 (Day 30)
| Intervention | Participants (Count of Participants) | |||||||
|---|---|---|---|---|---|---|---|---|
| Visit 1 - post-injection72557804 | Visit 1 - post-injection72557805 | Visit 2 - day 3072557804 | Visit 2 - day 3072557805 | |||||
| Responder | Not responder | |||||||
| RHA® Redensity With Lidocaine | 29 | |||||||
| RHA® Redensity With New Anesthetic Agent | 28 | |||||||
| RHA® Redensity With Lidocaine | 1 | |||||||
| RHA® Redensity With New Anesthetic Agent | 2 | |||||||
| RHA® Redensity With New Anesthetic Agent | 29 | |||||||
| RHA® Redensity With New Anesthetic Agent | 1 | |||||||
"self-reported acceptance of the procedure meant to assess a patient's acceptability through a scale~title: Please slide the tab along the line below to indicate, overall, how acceptable the procedure performed today was min: 0 (completely acceptable) max: 100 (not at all acceptable)" (NCT03654417)
Timeframe: up to 30 minutes after the procedure
| Intervention | units on a scale (mm) (Median) |
|---|---|
| EMLA | 0 |
| Lidocaine | 10.5 |
"self-reported level of anxiety immediately prior to the start of the procedure~title: Slide the tab along the line below to indicate how nervous you feel about the procedure you are about to have min: 0 (not nervous) max: 100 (very nervous)" (NCT03654417)
Timeframe: No more than 30 minutes before the procedure
| Intervention | units on a scale (mm) (Median) |
|---|---|
| EMLA | 19 |
| Lidocaine | 31.5 |
self-reported level of vulvar pain immediately prior to the start of the procedure title: Please slide the tab along the line below to indicate pain in the area of your vulva (external genitalia) during biopsy min: 0 (no pain) max: 100 (worst pain imaginable) (NCT03654417)
Timeframe: no more than 30 minutes prior to procedure
| Intervention | units on a scale (mm) (Median) |
|---|---|
| EMLA | 0.0 |
| Lidocaine | 0.0 |
"The highest pain score recorded (at time of numbing or at time of biopsy) controlled for baseline pain~title: Please slide the tab along the line below to indicate pain in the area of your vulva (external genitalia) during numbing OR biopsy min: 0 (no pain) max: 100 (worst pain imaginable)" (NCT03654417)
Timeframe: no more than 5 minutes after numbing or 5 minutes after biopsy
| Intervention | units on a scale (mm) (Median) |
|---|---|
| EMLA | 20 |
| Lidocaine | 56.5 |
"self-reported level of pain following the biopsy~title: Please slide the tab along the line below to indicate pain in the area of your vulva (external genitalia) during biopsy min: 0 (no pain) max: 100 (worst pain imaginable)" (NCT03654417)
Timeframe: No more than 5 minutes after receiving the biopsy
| Intervention | units on a scale (mm) (Median) |
|---|---|
| EMLA | 6 |
| Lidocaine | 3 |
"provider-reported measure of how well they believe the patient tolerated the procedure~title: Overall, how well did the subject tolerate the procedure today? min: 0 (well tolerated) max: 100 (poorly tolerated)" (NCT03654417)
Timeframe: Up to 30 minutes after the procedure
| Intervention | units on a scale (mm) (Median) |
|---|---|
| EMLA | 3 |
| Lidocaine | 15 |
"provider-reported measure of how well they believe the procedure went~title: Overall, how satisfied are you with the procedure performed today? min: 0 (completely satisfied) max: 100 (not at all satisfied)" (NCT03654417)
Timeframe: Up to 30 minutes after the procedure
| Intervention | units on a scale (mm) (Median) |
|---|---|
| EMLA | 3 |
| Lidocaine | 9.5 |
"self-reported tolerance of the procedure meant to assess a patient's tolerance through a scale~Title: Please slide the tab along the line below to indicate, overall, how you would rate the experience of your biopsy procedure today Min: 0 (I could easily handle having this procedure again) Max: 100 (I could never have this procedure done again)" (NCT03654417)
Timeframe: Up to 30 minutes after the procedure
| Intervention | units on a scale (mm) (Median) |
|---|---|
| EMLA | 2 |
| Lidocaine | 17 |
Change in strength in both groups greater than or equal to 20% weakness in one or more myotomes 30 minutes after CESI using a hand held Dynamometer. (NCT03127137)
Timeframe: 30 minutes after the CESI procedure
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Yes, greater or equal to 20% weakness in greater or equal to 1 or more myotome | No, greater or equal to 20% weakness in greater or equal to 1 or more myotome | |
| Experimental Group 1 With Lidocaine | 25 | 35 |
| Experimental Group 2 With Saline | 30 | 30 |
Assessed using the visual analog scale (0-10 scale). Zero indicates no pain, 10 indicates worst pain ever. (NCT03630198)
Timeframe: Assessed 1 minute after the injection (in clinic)
| Intervention | Score on a scale (Mean) |
|---|---|
| Corticosteroid With Lidocaine | 5.4 |
| Corticosteroid With Normal Saline | 2.7 |
Assessed using the visual analog scale (0-10 scale). Zero indicates no pain, 10 indicates worst pain ever. (NCT03630198)
Timeframe: Assessed at 6 hours and 24 hours after injection
| Intervention | Score on a scale (Mean) | |
|---|---|---|
| Pain (6 hour) | Pain (24 hour) | |
| Corticosteroid With Lidocaine | 0.9 | 0 |
| Corticosteroid With Normal Saline | 0.1 | 0 |
Pain measured by VAS (0-100mm; 0 being no pain, 100 being worst pain imaginable). (NCT03356145)
Timeframe: Up to 1 minute to complete survey
| Intervention | score on a scale (Median) |
|---|---|
| 12 mL Arm | 51 |
| 20 mL Arm | 58 |
(NCT03356145)
Timeframe: Up to 10 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| 12 mL Arm | 0 |
| 20 mL Arm | 0 |
The primary objective is to determine pain perceived immediately following dilator insertion measured by Visual Analogue Scale (VAS) (0-100mm; 0 being no pain, 100 being worst pain imaginable). (NCT03356145)
Timeframe: Time of dilator insertion (less than 1 minute to assess pain)
| Intervention | score on a scale (Median) |
|---|---|
| 12 mL Arm | 41 |
| 20 mL Arm | 49 |
"Global satisfaction (acceptability) of procedure reported by participant, measured by 0-100mm VAS; with anchors at 0 (worse than expected), 50 (what I expected), and 100 (better than expected)." (NCT03356145)
Timeframe: Up to 1 minute to complete survey
| Intervention | score on a scale (Median) |
|---|---|
| 12 mL Arm | 70 |
| 20 mL Arm | 53 |
"Measured by VAS (0-100mm; 0 being very easy, 100 being very difficult)." (NCT03356145)
Timeframe: Up to 1 minute to complete survey
| Intervention | score on a scale (Median) |
|---|---|
| 12 mL Arm | 27 |
| 20 mL Arm | 17 |
Defined as time of speculum insertion (NCT03356145)
Timeframe: Up to 10 minutes
| Intervention | minutes (Median) |
|---|---|
| 12 mL Arm | 5.5 |
| 20 mL Arm | 5.7 |
Side effects were not necessarily considered to be adverse events by investigator. (NCT03356145)
Timeframe: Up to 10 minutes
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Metallic taste | Ringing in ears | Dizziness or lightheadedness | Shaky legs | |
| 12 mL Arm | 2 | 2 | 1 | 0 |
| 20 mL Arm | 3 | 3 | 6 | 1 |
visual analog scale (VAS) 0 = no pain to 100 = worse pain possible Rather, this is a pain assessment during the actual procedure rather than during the pre-procedure lidocaine injection. (NCT01330134)
Timeframe: post procedure (day 1)
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine Onto Skin Prior to Lidocaine Subcutaneous Injection | 12.2 |
| Lidocaine Subcutaneous Injection Alone | 16.6 |
visual analog scale (VAS) 0= no pain to 100 = worse pain possible (NCT01330134)
Timeframe: post procedure (day 1)
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine Onto Skin Prior to Lidocaine Subcutaneous Injection | 18.4 |
| Lidocaine Subcutaneous Injection Alone | 20.8 |
Visual analog scale (VAS). This is a standardized analog scale with scores from 0-100. It measures level of pain with 0 meaning no pain and 100 meaning the most extreme level of pain. Higher values refer to a worse outcome. (NCT01330134)
Timeframe: post procedure (day 1)
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine Onto Skin Prior to Lidocaine Subcutaneous Injection | 15.3 |
| Lidocaine Subcutaneous Injection Alone | 19.0 |
Total pain reduction (mouth and throat) was measured by the numerical analogue scale of mouth pain on a scale of 0 to 10, with 0=no pain and 10=worst pain in the questionnaires taken at baseline, and 5, 15, 30, 60, 120, 240 minutes after assigned treatment for doxepin or DLA vs. placebo. The total pain reduction was calculated by the (average of mouth and throat) area under the curve (AUC) adjusting for baseline, with time scale (baseline, 5, 15, 30, 60, 120 and 240 minutes post treatment) replaced by a numerical scale of 0, 1, 2, 3, 4, 5 and 6 respectively. The AUC was prorated when there are terminal missing data. If the missing data were intermittent, simple imputation by trapezoidal rules were applied to calculate the AUC. If a patient cancelled, was missing baseline data, or only provided baseline data, he/she was excluded from the statistical analysis. (NCT02229539)
Timeframe: Baseline, 5, 15, 30, 60, 120, 240 minutes post treatment
| Intervention | units on a scale*time scale (Mean) |
|---|---|
| Doxepin | 11.9 |
| DLA (Diphenhydramine, Lidocaine and Antacid) | 11.7 |
| Placebo | 8.7 |
For the primary outcome, pain immediately after paracervical block injection was measured by a scale. The scale used was the 100-mm visual analog scale. The minimum score was 0 and the maximum score was 100. Higher numbers indicate worse pain. (NCT03107754)
Timeframe: Immediately after injection of the paracervical block
| Intervention | units on a scale (Median) |
|---|---|
| Standard Paracervical Block | 44.5 |
| Buffered Lidocaine Paracervical Block | 30 |
Pain scores were measured at multiple points throughout the procedure. Pain scores were measured using a 100 mm visual analog scale with 0 being no pain and 100 being the worst pain ever. (NCT03107754)
Timeframe: Immediately after speculum placement, cervical dilation, uterine aspiration
| Intervention | units on a scale (Median) | ||
|---|---|---|---|
| After insertion of speculum | After cervical dilation | After uterine aspiration | |
| Buffered Lidocaine Paracervical Block | 17 | 55 | 69 |
| Standard Paracervical Block | 13 | 60.06 | 67.5 |
0 to 100 mm visual analog scale, higher values represent more pain. (NCT01292447)
Timeframe: Day 1
| Intervention | score on a scale (Mean) |
|---|---|
| Control Group | 36.7 |
| Study Group | 35.2 |
"Blood oxygenation level dependent (BOLD) responses will allow the identification of relative activation/deactivation in the brain as a result of events (e.g. painful stimulations) that will be given during the experiment.~Changes in the Percentage of BOLD signal are calculated as the BOLD signal in the right supplementary motor area during the 20-second heat pain divided by the whole-brain average BOLD signal during that 20-second heat pain." (NCT03446456)
Timeframe: Day 2, the average of 24 trials of painful stimulations with each stimulation lasting 20 seconds
| Intervention | percentage of BOLD signal change (Mean) |
|---|---|
| Saline | 0.485 |
| Arginine Vasopressin | 0.482 |
On Day 1, the heating temperature was calibrated to the individual level. The heating temperature corresponding to 50 out of 100 visual analog scale pain ratings was selected as the testing temperature for day 2 (test). (NCT03446456)
Timeframe: Day 1 (calibration)
| Intervention | celsius degree (Mean) |
|---|---|
| Saline | 44.16 |
| Arginine Vasopressin | 44.44 |
"The IAT is a behavioral test that examines racial biases via measuring the strength of associations between concepts (e.g., African-American, Asian, White) and evaluations (good, bad). Participants were asked to press a response key when they saw images (people) or words (good/bad) on the screen. Response latencies (RL) were measured in milliseconds using E-prime as the reaction time to press the response key. An RL difference (D) score was calculated as 1) Compute the standard deviation (SD) of RL from overall trials; 2) M1 is the mean of RL in the condition where White and good share the same response key. M2 is the mean of RL in the condition where African-American/Asian people and good share the same response key; 3) D = (M2-M1)/SD.~The D score ranges from -2 to +2. Positive values indicate a racial preference for White people. Negative values indicate a racial preference for African-American/Black or Asian people. A value close to 0 indicates no racial preference." (NCT03446456)
Timeframe: Day 1
| Intervention | difference score (Mean) |
|---|---|
| Saline | 0.03 |
| Arginine Vasopressin | 0.07 |
Participants will provide their pain on a Visual Analogue Scale raging from 0=no pain to 100= maximum unbearable pain. Normal value will be absence of pain. (NCT03446456)
Timeframe: Day 2 (test)
| Intervention | units on a scale (Mean) |
|---|---|
| Saline | 44.84 |
| Arginine Vasopressin | 47.19 |
Swelling at vaccination site (NCT02807623)
Timeframe: baseline, 48-72 hours, and 21- 28 days (3 points)
| Intervention | Participants (Count of Participants) |
|---|---|
| Baseline | 0 |
| 48-72 Hours After Vaccination | 0 |
| 21-28 Days After Vaccination | 0 |
Reddening of the skin at vaccination site reported as the total number of participants with erythema over the duration of the study. (NCT02807623)
Timeframe: baseline, 48- 72 hours, 21-28 days (3 points)
| Intervention | Participants (Count of Participants) |
|---|---|
| Baseline | 0 |
| 48-72 Hours After Vaccination | 0 |
| 21-28 Days After Vaccination | 0 |
A Lactate meter was used to test the exercise group for lactate readings. Two lactate tests was performed for the exercise group at Visit 1, both pre and post Influenza vaccination. The first lactate reading was taken after the blood draw.The second lactate reading was obtained from a fingerstick from the hand opposite to the vaccination arm, ideally within 3-8 minutes after the study subject completes pushups. (NCT02807623)
Timeframe: Immediately prior to Influenza vaccine and 3-8 minutes after Influenza vaccine was administered and after push-ups were completed.
| Intervention | mmol/L (Mean) | |
|---|---|---|
| Lactate before pushups | Lactate after pushups | |
| Compound Exercise of Push-ups | 1.51 | 7.69 |
Level of Pain will be measured by validated pain scale, using a scale of 0 ( best, no pain) to 10 (worst, as bad as imaginable, completely interferes). (NCT02807623)
Timeframe: baseline, 48-72 hours and at 21-28 days ( 3 points )
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Visit 1 | Visit 2 | Visit 3 | |
| Compound Exercise of Push-ups | .14 | .19 | .13 |
| Ibuprofen | .39 | .56 | .28 |
| Placebo | .19 | .22 | .06 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 214.80 | 345.09 |
| Ibuprofen | 171.00 | 239.25 |
| Placebo | 216.75 | 343.03 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 149.22 | 232.58 |
| Ibuprofen | 177.78 | 243.13 |
| Placebo | 221.09 | 296.66 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 26.00 | 41.02 |
| Ibuprofen | 17.41 | 25.47 |
| Placebo | 26.09 | 34.09 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 32.89 | 49.07 |
| Ibuprofen | 40.16 | 47.34 |
| Placebo | 36.69 | 44.78 |
Time to gum numbness, assessed using periodontal probe and patient response. (NCT04055116)
Timeframe: Time of injection to 4 minutes post-injection (tested in 15 second intervals).
| Intervention | seconds (Mean) |
|---|---|
| Unbuffered Lidocaine | 102.21 |
| Buffered Lidocaine | 81.07 |
Wong-Baker FACES Pain Rating Scale responses after buffered and non-buffered lidocaine. Range: 0 - No Hurt to 10 - Hurts Worst (higher numbers indicate higher levels of pain). There are no sub-scores. (NCT04055116)
Timeframe: Within 1 minute of anesthetic administration
| Intervention | units on a scale (Mean) |
|---|---|
| Unbuffered Lidocaine | 3.52 |
| Buffered Lidocaine | 3.48 |
Faces, Legs, Arms, Crying Consolability (FLACC) Behavioral Pain Scale. This scale helps clinicians assess patients' pain based on behavioral observations. Range: 0 - 2 per category (higher number indicates more observed agitation/potential pain). A score is given in each of the five categories (Faces, Legs, Arms, Crying, Consolability). The sum of these scores provides the Assessment of Behavioral Score (range: 0 - 10) with higher scores indicating higher levels of pain. (NCT04055116)
Timeframe: During local anesthesia administration
| Intervention | units on a scale (Mean) |
|---|---|
| Unbuffered Lidocaine | 1.88 |
| Buffered Lidocaine | 2.43 |
Patient reported NRS pain scores after Blunt Dissection. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 4.1 |
| Placebo | 4.4 |
Patient reported NRS pain scores after Irrigation. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 3.4 |
| Placebo | 2.6 |
Patient reported NRS pain scores after Lidocaine injection. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Following Lidocaine injection measured once anytime up to 12 minutes after intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 8.4 |
| Placebo | 8.0 |
Patient reported pain after Packing of abscess. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once at the time of completion of application of the bandage, up to 60 minutes following intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 4.5 |
| Placebo | 3.9 |
Patient reported NRS pain scores following Incision. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 3.9 |
| Placebo | 3.9 |
Patient reported pain scores at baseline. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Baseline
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 8.3 |
| Placebo | 8.1 |
Patient reported pain scores for overall Procedure assessed immediately after placement of dressing at the end of procedure. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once following placement of dressing at completion of procedure, up to 60 minutes following intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 6.2 |
| Placebo | 7.0 |
Measures how pain is affecting the patients lifestyle on a scale from 0 to 10 as defined by each question. The questionnaire contains 15 questions that each range on a scale form 0 to 10. The total score of the questionnaire ranges from 0 to 150. Lower values represent a better outcome. (NCT03511053)
Timeframe: Change between baseline, 1 month and 2 months post injection
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| Average at baseline | Average at 1 month | Average at 2 months | Average at 1 month change | Average at 2 month change | |
| All Participants | 77.5 | 53.3 | 64.3 | 27.3 | 16.2 |
Measures how pain due to spinal stenosis is effected the patient based on quality of life/pain questions and satisfaction questions for months 1 and 2 (no scales are used) SSSQ scores are reported in percentages 0-100%, higher scores indicate worse outcomes. (NCT03511053)
Timeframe: Change between baseline, 1 month and 2 months post injection
| Intervention | Percentage (Mean) | ||||
|---|---|---|---|---|---|
| Average at baseline | Average at 1 month | Average at 2 months | Average at 1 month change | Average at 2 month change | |
| All Participants | 64.1 | 53.2 | 53.5 | 11.7 | 10.3 |
Number rating of back/leg pain from 0 to 10, 0 being no pain/discomfort, 10 being extreme pain/discomfort (NCT03511053)
Timeframe: Change between baseline, 1 month and 2 months post injection
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| Average at baseline | Average at 1 month | Average at 2 months | Average 1 month change | Average 2 month change | |
| All Participants | 6.2 | 5.0 | 5.0 | 0.8 | 1 |
Leg Pain NRS 0-10 scale (NCT01238536)
Timeframe: 12 months
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Steroid Injection | 4.7 |
| Epidural Local Anesthetic Injection | 4.3 |
Leg Pain NRS is a second primary outcome at 6 weeks We measured leg pain using a 0-10 pain NRS (0=no pain and 10=worst pain imaginable) assessing average pain over the past week. (NCT01238536)
Timeframe: 6 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Steroid Injection | 4.4 |
| Epidural Local Anesthetic Injection | 4.6 |
The primary outcome measure will be back specific functional status, measured by the Roland Scale at 6 weeks. The RDQ is a back pain specific functional status questionnaire adapted from the Sickness Impact Profile (SIP). The RDQ consists of 24 yes/no items, which represent common dysfunctions in daily activities experienced by subjects with low back pain. A single unweighted score is derived by summing the 24 items, with higher scores indicating worse function with 0 (no disability) to 24 (maximum disability). Our primary analysis will be a simple 2-group comparison of the mean Roland score as an evaluation of the short-term efficacy of epidural steroid injection. (NCT01238536)
Timeframe: 6 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Steroid Injection | 11.8 |
| Epidural Local Anesthetic Injection | 12.5 |
The RDQ is a back pain specific functional status questionnaire adapted from the Sickness Impact Profile (SIP). The RDQ consists of 24 yes/no items, which represent common dysfunctions in daily activities experienced by subjects with low back pain. A single unweighted score is derived by summing the 24 items, with higher scores indicating worse function with 0 (no disability) to 24 (maximum disability). Our primary analysis will be a simple 2-group comparison of the mean Roland score as an evaluation of the short-term efficacy of epidural steroid injection. (NCT01238536)
Timeframe: 12 months
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Steroid Injection | 12.0 |
| Epidural Local Anesthetic Injection | 11.5 |
Median pain score on a 0 (no pain) to 10 (worst pain) numeric rating scale 1 hour after osmotic dilator insertion assessed via text message (NCT04254081)
Timeframe: 1 hour after osmotic dilator insertion
| Intervention | score on a scale (Median) |
|---|---|
| Buprenorphine 0.15mg + 1% Lidocaine Paracervical Block | 2 |
| 1% Lidocaine Paracervical Block | 3.5 |
Median pain score on a 0 (no pain) to 10 (worst pain) numeric rating scale 2 hours after osmotic dilator insertion assessed via text message (NCT04254081)
Timeframe: 2 hours after osmotic dilator insertion
| Intervention | score on a scale (Median) |
|---|---|
| Buprenorphine 0.15mg + 1% Lidocaine Paracervical Block | 3 |
| 1% Lidocaine Paracervical Block | 3.5 |
Median pain score on a 0 (no pain) to 10 (worst pain) numeric rating scale 6 hours after osmotic dilator insertion assessed via text message (NCT04254081)
Timeframe: 6 hours after osmotic dilator insertion
| Intervention | score on a scale (Median) |
|---|---|
| Buprenorphine 0.15mg + 1% Lidocaine Paracervical Block | 3 |
| 1% Lidocaine Paracervical Block | 3 |
Median pain score on a 0 (no pain) to 10 (worst pain) numeric rating scale at the time of osmotic dilator insertion (NCT04254081)
Timeframe: Assessed immediately after last dilator inserted
| Intervention | score on a scale (Median) |
|---|---|
| Buprenorphine 0.15mg + 1% Lidocaine Paracervical Block | 3.5 |
| 1% Lidocaine Paracervical Block | 4.0 |
We asked the participant to rate her pain on a 100 mm Visual Analog Scale (VAS) immediately after laminaria was placed. The VAS is a validated measure of pain where 0=no pain and 100=worst pain ever felt. (NCT02454296)
Timeframe: Measured within 10 seconds after placement of laminaria
| Intervention | units on a scale (100 mm VAS) (Median) |
|---|---|
| Paracervical Block With Lidocaine | 13 |
| Sham Paracervical Block | 54 |
Participants reported her pain level on the 100 mm Visual Analog Scale (VAS) within 10 seconds after she received either the paracervical block or the sham block. The VAS is a validated measure of pain where 0=no pain and 100=worst pain ever felt. (NCT02454296)
Timeframe: Within 10 seconds after receiving paracervical or sham block
| Intervention | units on a scale (100 mm VAS) (Median) |
|---|---|
| Paracervical Block Group | 14 |
| Sham Block Group | 27 |
Patients rated their satisfaction with overall pain control on the 100 mm VAS, with 0 as not satisfied at all and 100 as completely satisfied (NCT02454296)
Timeframe: 15 minutes post-operatively
| Intervention | units on a scale (100 mm VAS) (Median) |
|---|---|
| Paracervical Block Group | 95 |
| Sham Block Group | 70 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given prior to administration of study drugs, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 3 |
| Active Drug Arm: Lorazepam and Oxycodone | 2 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: Immediately after the last dilator is placed, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 55 |
| Active Drug Arm: Lorazepam and Oxycodone | 44 |
Assess whether desired number of dilators was not able to be successfully inserted, comparing 2 arms. (NCT03202550)
Timeframe: After speculum removed, up to 30 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Placebo Arm | 13 |
| Active Drug Arm: Lorazepam and Oxycodone | 10 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever). This was to be assessed at 15 minutes after last dilator is placed. Some participants had this assessment done up to 45 minutes after last dilator was placed because it could not be done at 15 minutes (some were being attended to by a nurse at the 15 minutes mark). (NCT03202550)
Timeframe: Assessed up to 45 minutes after last dilator placed
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 29 |
| Active Drug Arm: Lorazepam and Oxycodone | 13 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given immediately after first dilator placed, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 50 |
| Active Drug Arm: Lorazepam and Oxycodone | 9 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given at time of speculum placement, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 20 |
| Active Drug Arm: Lorazepam and Oxycodone | 11 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: Immediately scored at time of tenacula placement, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 31 |
| Active Drug Arm: Lorazepam and Oxycodone | 50 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given before specula placed, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 1 |
| Active Drug Arm: Lorazepam and Oxycodone | 1 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given at time of paracervical block administration, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 57 |
| Active Drug Arm: Lorazepam and Oxycodone | 51 |
Pain score based on numeric rating scale (NRS [0 lowest value to 10 highest value, in which 0 is the lowest amount of pain and 10 is the highest amount of pain]); Baseline obtained prior to study drug ingestion/dilator insertion. NRS pain score obtained via text message. (NCT03080493)
Timeframe: 2 hours after insertion of last osmotic dilator
| Intervention | Numeric rating scale pain score change (Median) |
|---|---|
| Gabapentin | 3.5 |
| Placebo Oral Capsule | 4 |
Pain score based on numeric rating scale (NRS [0 lowest value to 10 highest value, in which 0 is the lowest amount of pain and 10 is the highest amount of pain]); Baseline obtained prior to study drug ingestion/dilator insertion. NRS pain score obtained via text message. (NCT03080493)
Timeframe: 4 hours after insertion of last osmotic dilator
| Intervention | Numeric rating scale pain score change (Mean) |
|---|---|
| Gabapentin | 3 |
| Placebo Oral Capsule | 3.5 |
Pain score based on numeric rating scale (NRS [0 lowest value to 10 highest value, in which 0 is the lowest amount of pain and 10 is the highest amount of pain]); Baseline obtained prior to study drug ingestion/dilator insertion. NRS pain score obtained in person before subject leaves clinic appointment. (NCT03080493)
Timeframe: 5 minutes after insertion of last osmotic dilator
| Intervention | Numeric rating scale pain score change (Median) |
|---|---|
| Gabapentin | 1 |
| Placebo Oral Capsule | 2 |
Pain score based on numeric rating scale (NRS [0 lowest value to 10 highest value, in which 0 is the lowest amount of pain and 10 is the highest amount of pain]); Baseline obtained prior to study drug ingestion/dilator insertion. NRS pain score obtained via text message. (NCT03080493)
Timeframe: 8 hours after insertion of last osmotic dilator
| Intervention | Numeric rating scale pain score change (Median) |
|---|---|
| Gabapentin | 2 |
| Placebo Oral Capsule | 2.5 |
Pain score based on numeric rating scale (NRS [0 lowest value to 10 highest value, in which 0 is the lowest amount of pain and 10 is the highest amount of pain]); Baseline obtained prior to study drug ingestion/dilator insertion. NRS pain score obtained in person upon presentation for D&E procedure. (NCT03080493)
Timeframe: Time of presentation for D&E (day after dilator insertion)
| Intervention | Numeric rating scale pain score change (Median) |
|---|---|
| Gabapentin | 0.5 |
| Placebo Oral Capsule | 1 |
Subject account of how many used acetaminophen/codeine (standard medications given for supplement NSAID as needed after dilator insertion) (NCT03080493)
Timeframe: Collected between each subject contact (2 hours, 4 hours, 8 hours after dilator insertion and at time of presentation for D&E procedure)
| Intervention | Participants (Count of Participants) |
|---|---|
| Gabapentin | 35 |
| Placebo Oral Capsule | 40 |
Self-reported highest level of pain between dilator placement and D&E on 100mm visual analog scale (VAS). Range is from 0mm to 100mm, with 0mm being the least amount of pain (minimum score) and 100mm being the greatest (maximum score). Higher values are considered a worse outcome. (NCT03868787)
Timeframe: 5 mins after dilator placement to 36 hours after dilator placement
| Intervention | units on a scale (Median) |
|---|---|
| Active TENS | 39 |
| Sham TENS | 55 |
Self-reported pain on 100mm visual analog scale (VAS) immediately following dilator placement. Range is from 0mm to 100mm, with 0mm being the least amount of pain (minimum score) and 100mm being the greatest (maximum score). Higher values are considered a worse outcome. (NCT03868787)
Timeframe: within 5 mins after dilator placement procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Active TENS | 64 |
| Sham TENS | 60.5 |
Patient satisfaction with device based on 4 questions with 5 point Likert scale. Minimum value is 1, maximum is 5. Higher score is a better outcome. (NCT03868787)
Timeframe: 24-36 hours after dilator placement, immediately prior to D&E
| Intervention | score on a scale (Median) | |||
|---|---|---|---|---|
| Pain control | Comfort | Ease of use | Would you use again | |
| Active TENS | 4 | 5 | 2 | 3 |
| Sham TENS | 3 | 4 | 4 | 2 |
Measure effectiveness of placebo as an adjunct to ibuprofen and paracervical block for pain control during uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive placebo adhesives and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). (NCT03391986)
Timeframe: prior to the procedure (baseline), at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Placebo Adhesives | 70.0 |
| Routine Care | 71.0 |
Using a satisfaction survey (investigator-developed, 6 questions, each question is graded on a scale of 1-5, 1 being very poor and 5 being very good) to measure effectiveness of auricular acupuncture for improving satisfaction. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 5-10 minutes)
| Intervention | percentage of participants (Number) |
|---|---|
| Pyonex Needles | 94 |
| Routine Care | 76 |
Measure effectiveness of auricular acupuncture as an adjunct to ibuprofen and paracervical block for pain control during first trimester uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive auricular acupuncture and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). The VAS has no sub-scales. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Pyonex Needles | 39.5 |
| Routine Care | 71.0 |
This is the amount of pain self-reported by the patient at the time of cervical dilation. VAS ranged from 0 to 100 mm, 0 equals no pain, 100 equals worse pain imaginable. (NCT02447029)
Timeframe: At time of cervical dilation, 30 minutes after lidocaine administration
| Intervention | units on a scale (Median) |
|---|---|
| Active Comparator | 68 |
| Standard Lidocaine Paracervical Block | 65 |
(NCT02447029)
Timeframe: Rate of complications at the end of the study
| Intervention | Participants (Count of Participants) |
|---|---|
| Active Comparator | 0 |
| Standard Lidocaine Paracervical Block | 0 |
This is the level of overall satisfaction self-reported by the patient at the completion of the procedure and prior to discharge. VAS ranged from 0 to 100 mm, 0 equals not satisfied, 100 equals highest satisfaction possible. (NCT02447029)
Timeframe: 30-45 minutes after completion of procedure
| Intervention | units on a scale (Median) |
|---|---|
| Active Comparator | 86 |
| Standard Lidocaine Paracervical Block | 92.5 |
This is the amount of pain self-reported by the patient 30-45 minutes after procedure. VAS ranged from 0 to 100 mm, 0 equals no pain, 100 equals worse pain imaginable. (NCT02447029)
Timeframe: Pain prior to discharge home: 30-45 minutes after completion of procedure
| Intervention | units on a scale (Median) |
|---|---|
| Active Comparator | 9 |
| Standard Lidocaine Paracervical Block | 11.5 |
This is the amount of pain self-reported by the patient prior to the procedure (Anticipated pain). VAS ranged from 0 to 100 mm, 0 equals no pain, 100 equals worse pain imaginable. (NCT02447029)
Timeframe: Pain level prior to procedure
| Intervention | units on a scale (Median) |
|---|---|
| Active Comparator | 59 |
| Standard Lidocaine Paracervical Block | 56 |
This is the amount of pain self-reported by the patient at the time of speculum insertion. VAS ranged from 0 to 100 mm, 0 equals no pain, 100 equals worse pain imaginable. (NCT02447029)
Timeframe: Pain at time of speculum insertion
| Intervention | units on a scale (Mean) |
|---|---|
| Active Comparator | 19.5 |
| Standard Lidocaine Paracervical Block | 22.3 |
This is the amount of pain self-reported by the patient at the time of tenaculum placement. VAS ranged from 0 to 100 mm, 0 equals no pain, 100 equals worse pain imaginable. (NCT02447029)
Timeframe: Pain at time of tenaculum placement
| Intervention | units on a scale (Mean) |
|---|---|
| Active Comparator | 39.8 |
| Standard Lidocaine Paracervical Block | 32.4 |
To assess change in pain from baseline to IUD insertion measured on a visual analog scale (VAS) from 0 mm (no pain) to 100 mm (worst pain in patient's life). This pain assessment was prior to (baseline) and at the time of IUD insertion following vaginal self-administration of study gel (either 2% lidocaine gel or placebo gel). (NCT01534520)
Timeframe: change in pain score from baseline (before IUD insertion) to time of IUD insertion
| Intervention | change in visual analog scale score (Median) |
|---|---|
| Group 1: Intravaginal 2% Lidocaine Gel | 61 |
| Group 2: Intravaginal Placebo Gel | 68 |
Number of women taking pain medication for at least one day following IUD insertion (NCT01534520)
Timeframe: 7 days post-insertion
| Intervention | participants (Number) |
|---|---|
| Group 1: Intravaginal 2% Lidocaine Gel | 24 |
| Group 2: Intravaginal Placebo Gel | 27 |
"The physician who conducted the study visit and IUD insertion was asked about the difficulty/ease in placing the IUD immediately following the procedure and the percentage of IUD insertions considered to be easy was calculated for each study group." (NCT01534520)
Timeframe: Directly after IUD insertion
| Intervention | percentage of insertions declared easy (Number) |
|---|---|
| Group 1: Intravaginal 2% Lidocaine Gel | 87 |
| Group 2: Intravaginal Placebo Gel | 64 |
"Number of participants who rated self-application of study gel as some what easy or very easy on Likert scale" (NCT01534520)
Timeframe: After inserting the gel but prior to IUD insertion
| Intervention | participants who found gel easy to use (Number) |
|---|---|
| Group 1: Intravaginal 2% Lidocaine Gel | 29 |
| Group 2: Intravaginal Placebo Gel | 29 |
Participant anxiety was measured by the study participant and the objective observer before (anticipatory), during (venipuncture) and after (recovery) venipuncture using a validated visual analog scale (VAS). The VAS is a validated scale that is used to detect small changes in many types of observations. The scale ranges from 0-100 scores on a scale, and here the higher scores indicate higher anxiety levels. Only the participant's mean venipuncture (during venipuncture) anxiety scores are presented in outcome measure results here. (NCT00676364)
Timeframe: During venipuncture
| Intervention | scores on a scale (Mean) |
|---|---|
| ControI Group Receiving Placebo Cream | 43.1 |
| Investigational Group | 40.5 |
"Pain was measured immediately after venipuncture by the participant using the six-point FACES scale. FACES in not an acronym, but rather a description of a pain scale that uses pictures of faces in various states of pain. The FACES pain scale is a common scale used to measure pain with scores on a scale. The scale we used had six points from zero (0) to five (5) indicating different levels of pain. Lower scores indicate lower levels of pain, and higher scores indicate higher levels of pain." (NCT00676364)
Timeframe: Pain was measured immediately after venipuncture.
| Intervention | scores on a scale (Mean) |
|---|---|
| ControI Group Receiving Placebo Cream | 2.2 |
| Investigational Group Receiving 4% Lidocaine Cream | 2.1 |
"IUD was inserted following the manufacturer's instructions, and a pain score was immediately obtained. Pain was scored on 0-9 scale; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Immediately after IUD placement
| Intervention | units on a scale of 0-9 (Mean) |
|---|---|
| Lidocaine | 2.95 |
| Normal Saline | 3.68 |
"Pain score on 0-9 scale for tenaculum placement (without anesthesia); with 0 being no pain and 9 being worst pain in life. Taken to adjust for different pain thresholds among subjects" (NCT01311102)
Timeframe: Immediately following tenaculum placement
| Intervention | units on a scale of 0-9 (Mean) |
|---|---|
| Lidocaine | 2.20 |
| Normal Saline | 2.70 |
"After liquid infused into three parts of the endometrial cavity: in the lower one third, the middle, and at the top of the cavity. Pain was scored on a 0-9 scale; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Recorded at the end of the infusion
| Intervention | units on a scale of 0-9 (Mean) |
|---|---|
| Lidocaine | 2.50 |
| Normal Saline | 3.39 |
"Pain score on 0-9 scale obtained just before the patient left the examination room; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Before patient left the examination room at conclusion of procedure
| Intervention | units on a scale of 0-9 (Mean) |
|---|---|
| Lidocaine | 2.12 |
| Normal Saline | 1.73 |
"The Faces Pain Scale Revised (FPS-R) is numerical self-report measure of pain intensity developed for children to score the sensation of pain from 0-10. Pictures of 6 cartoon faces ranging from neutral expression of no pain (0) to very much pain (10)." (NCT01394250)
Timeframe: Baseline and 30 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Buzzy® | -3.544 |
| Topical Lidocaine 4% Cream | -3.436 |
The Face, Legs, Activity, Cry, Consolability scale or FLACC scale is a measurement used to assess pain for children between the ages of 2 months and 7 years or individuals that are unable to communicate their pain. The scale is scored in a range of 0-10 with 0 representing no pain. The scale has five criteria, which are each assigned a score of 0, 1 or 2. The FLACC score was completed immediately after IV cannulation by a member of the clinical care team who was not part of the study. During initial trial design, the goal was to collect FLACC score pre and post cannulation; however, it was decided prior to enrollment that FLACC score would not be collected pre cannulation, only post. (NCT01394250)
Timeframe: Up to 5 minutes after IV Cannulation
| Intervention | units on a scale (Median) |
|---|---|
| Buzzy® | 0.667 |
| Topical Lidocaine 4% Cream | 0.333 |
"Ten seconds following injection of propofol, subjects were asked Are you having pain at your IV site? Any behavioral signs were noted. Injection pain was assessed using the following four point scale: 0 = no pain; 1 = mild pain (pain reported only in response to questioning and without behavioral signs); 2 = moderate pain (pain reported in response to questioning and accompanied by a behavioral sign, or pain reported spontaneously without questioning); and 3 = severe pain (strong vocal response or response accompanied by facial grimacing, arm withdrawal, or tears)." (NCT01342510)
Timeframe: < 1 minute.
| Intervention | participants reporting pain (Number) |
|---|---|
| Lidocaine | 11 |
| Magnesium | 25 |
| Lidocaine/Magnesium | 15 |
| Control | 18 |
Following injection of the study drug, 50 mg of propofol will be injected. Ten seconds after propofol, subjects will be asked a standard question about pain. Behavioral signs will be noted. Pain will be assessed using a four point scale: 0=no pain, 1=mild pain (pain reported only in response to questioning and without behavioral signs), 2=moderate pain (pain reported in response to questioning and a behavioral sign, or pain reported without questioning), 3=severe pain (strong vocal response or behavioral response). (NCT01342510)
Timeframe: Approximately 10 seconds following administration of propofol.
| Intervention | percentage of patients reporting pain (Number) |
|---|---|
| Lidocaine | 29 |
| Magnesium | 57 |
| Lidocaine/Magnesium | 41 |
| Control | 46 |
Immediately after receiving an injection, subjects will rate their perceived pain level, using a validated measure. Subject was asked to quantify the pain of every injection using a validated scale from 0 through 10, with 0 being no pain and 10 being severe pain that is disabling. The effect of treatment was estimated by taking the difference of the mean buffered and SOC pain scores and a paired t-test was used to test whether the mean difference was significantly different from 0. Perceived pain levels assessed after each injection were averaged for each participant. (NCT01660412)
Timeframe: immediately after administration (<1 min) of each injection (up to total 5 minutes)
| Intervention | units on a scale (Mean) |
|---|---|
| Standard of Care Injection | 5.81 |
| PH Altered Injection | 4.39 |
"A Likert visual analog scale will be used to document each study participant's level of pain experienced during injection of the cervical block.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine Arm | 25 |
| Buffered Lidocaine | 19 |
"A Likert visual analog scale will be used to document each study participant's level of pain experienced during injection of the cervical block.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of the procedure
| Intervention | units on a scale (Median) |
|---|---|
| Lidocaine Arm | 26 |
| Buffered Lidocaine | 18 |
"A Likert visual analog scale will be used to determine the overall pain experienced by each study participant including injection pain, procedural pain, and cramping.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Injection pain | Procedure pain | Cramping pain | |
| Buffered Lidocaine | 19 | 19 | 18 |
| Lidocaine Arm | 25 | 27 | 19 |
"A Likert visual analog scale will be used to determine the overall pain experienced by each study participant including injection pain, procedural pain, and cramping.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Median) | ||
|---|---|---|---|
| Injection pain | Procedure pain | Cramping pain | |
| Buffered Lidocaine | 18 | 13 | 14 |
| Lidocaine Arm | 26 | 25 | 19 |
Rates of Satisfied and very satisfied are used to be compared between two groups. (NCT01744197)
Timeframe: 30 minutes after the venipuncture.
| Intervention | percentage of participants (Number) |
|---|---|
| Synera | 74.0 |
| Placebo | 53.7 |
The primary efficacy endpoint is the subject's report of pain intensity regarding the venipuncture using a 0-10 VAS. The VAS <3 is considered as patients with no or minor pain and would be compared between 2 groups. (NCT01744197)
Timeframe: 30 minutes after the venipuncture.
| Intervention | percentage of participants (Number) |
|---|---|
| Synera | 38.0 |
| Placebo | 21.3 |
The primary efficacy endpoint is the subject's report of pain intensity regarding the venipuncture using a 0-10 VAS. The VAS =0 is considered as patients with no pain and would also be compared between 2 groups. (NCT01744197)
Timeframe: 30 minutes after the venipuncture.
| Intervention | percentage of participants (Number) |
|---|---|
| Synera | 19.4 |
| Placebo | 8.3 |
Participant will complete a questionnaire to evaluate his/her pain level perception using a Visual Analog Scale (VAS) during injection of HA filler to the upper lip. The Visual Analog scale uses a 10 cm horizontal line with 'no pain' labeled on the left end of line and 'worst pain' on the right end of line. Participant marks their pain level at any point on the line from no pain to worst pain. No pain= 0 cm, Worst pain=10cm (NCT02379221)
Timeframe: 5-10 minutes post procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Injectable | 0.89 |
| Topical | 3.67 |
A mean level of pain for all participants completing the Visual Analog Scale (VAS) during injection of HA filler to the lower lip. The Visual Analog scale uses a 10 cm horizontal line with 'no pain' labeled on the left end of line and 'worst pain' on the right end of line. Participant marks their pain level at any point on the line from no pain to worst pain. No pain= 0 cm, Worst pain=10cm. The total score was divided by 48. (NCT02379221)
Timeframe: 5-10 minutes post procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Injectable | 1.47 |
| Topical | 4.38 |
Participant will complete a questionnaire to evaluate his/her pain level perception using a Visual Analog Scale (VAS) during injection of HA filler to the nasolabial fold. The Visual Analog scale uses a 10 cm horizontal line with 'no pain' labeled on the left end of line and 'worst pain' on the right end of line. Participant marks their pain level at any point on the line from no pain to worst pain. No pain= 0 cm, Worst pain=10cm (NCT02379221)
Timeframe: 5-10 minutes post procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Injectable | 0.76 |
| Topical | 2.82 |
Participant will complete a questionnaire to evaluate his/her pain level perception using a Visual Analog Scale (VAS) during injection to the upper and lower lip. The Visual Analog scale uses a 10 cm horizontal line with 'no pain' labeled on the left end of line and 'worst pain' on the right end of line. Participant marks their pain level at any point on the line from no pain to worst pain. No pain= 0 cm, Worst pain=10cm (NCT02379221)
Timeframe: 5-10 minutes post-procedure
| Intervention | unit on a scale (Mean) |
|---|---|
| Upper Lip | 2.14 |
| Lower Lip | 1.89 |
Participant will complete a questionnaire to evaluate his/her pain level perception using a Visual Analog Scale (VAS) during application of topical anesthesia to the upper and lower lip. The Visual Analog scale uses a 10 cm horizontal line with 'no pain' labeled on the left end of line and 'worst pain' on the right end of line. Participant marks their pain level at any point on the line from no pain to worst pain. No pain= 0 cm, Worst pain=10cm (NCT02379221)
Timeframe: 5-10 min post procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Upper Lip | 0.05 |
| Lower Lip | 0.11 |
Patient will complete a questionnaire to evaluate his/her preference of anesthetic modality. (NCT02379221)
Timeframe: one week post treatment
| Intervention | participant preference selection (Number) |
|---|---|
| Injectable | 32 |
| Topical | 16 |
"Discomfort according to the Eye Sensation Scale: 1-none, 2- mild, 3- moderate, 4- severe, 5- extremely severe~Patient satisfaction scale: 1=very unsatisfied, 2=unsatisfied, 3=neutral, 4=satisfied, 5= extremely satisfied" (NCT01087489)
Timeframe: immediately after injection, 1- hour later, and next day
| Intervention | units on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| Discomfort during anesthetic preparation | Discomfort during needle penetration | Satisfaction with entire prep and injection | Discomfort 1 h after injection | Discomfort day after injection | Next day satisfaction with injection | |
| 3.5% Ophthalmic Lidocaine Gel | 2.09 | 2.0 | 4.5 | 2.1 | 1.6 | 4.3 |
| 4% Liquid Lidocaine Method | 2.1 | 1.7 | 4.3 | 2.4 | 1.8 | 4.3 |
intraocular pressure (IOP) was measured immediately after the injection, and at 5, 10, and 15 minutes after the injection (until it was 30 mmHg or below). Prior to injection IOP and post-injection IOP were compared to find the IOP change after injection. (NCT01087489)
Timeframe: immediately after injection, at 5, 10, 15 minutes
| Intervention | mmHg (Mean) | |
|---|---|---|
| baseline IOP before injection | IOP change after 0.05 cc injection | |
| 3.5% Ophthalmic Lidocaine Gel | 15.9 | 30.9 |
| 4% Liquid Lidocaine Method | 15.5 | 25.7 |
"Presence of corneal staining after the injection:~Quadrants of fluorescein staining: 0 1 2 3 4~Density of staining: 0- None 1- Mild 2- Moderate 3- Severe 4- corneal abrasion~Size of subconjunctival hemorrhage:~in clock hours" (NCT01087489)
Timeframe: within 10 minutes of the injection
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Corneal fluorescein staining | Density of corneal staining | |
| 3.5% Ophthalmic Lidocaine Gel | 2.3 | 1.3 |
| 4% Liquid Lidocaine Method | 3.0 | 1.9 |
A sterile catheter lubricated with the allocated gel was placed transurethrally into the bladder to measure the postvoid residual volume. After removal of the catheter, a cotton swab, coated with the same allocated gel, was advanced to the urethrovesical junction until resistance was felt. The angle of the swab with the horizontal plane was measured at rest and with a Valsalva maneuver. Immediately following the Q-tip test, the patient's perception of pain level was measured by Wong-Baker FACES Pain Scale, a visual scale where 0 represents no pain and 5 represents worst imaginable pain. (NCT00883103)
Timeframe: Immediately after the examination
| Intervention | Scores on a scale (Median) |
|---|---|
| Lidocaine | 1 |
| Aqueous Gel | 2 |
Evaluate pain on an 11-point scale, where 0 is no pain and 10 is the worst pain imaginable. (NCT00653861)
Timeframe: 1 day
| Intervention | Units on a scale (Mean) |
|---|---|
| Juvéderm Lidocaine Nasolabial Folds (NLFs) | 2.0 |
| Juvéderm Nasolabial Folds (NLFs) | 5.4 |
A 5-point scale (-2 = Right NLF more painful than Left NLF; -1 = Right NLF slightly more painful than Left NLF; 0 = No difference; 1 = Left NLF slightly more painful than Right NLF; 2 = Left NLF more painful than Right NLF). Subjects selected one category from the scale; the percentage of subjects that selected each category is presented. (NCT00653861)
Timeframe: 1 day
| Intervention | Percent of Participants (Number) | ||||
|---|---|---|---|---|---|
| Juvéderm Lidocaine is Less Painful than Juvéderm | Juvéderm Lidocaine is Slightly Less Painful | No Difference | Juvéderm Lidocaine is Slightly More Painful | Juvéderm Lidocaine is More Painful than Juvéderm | |
| Total Study Participants | 64 | 29 | 0 | 4 | 3 |
Determination of improvement in NLF severity score on 5-point NLF Severity Scale (0 = None; 1 = Mild; 2 = Moderate; 3 = Severe; 4 = Extreme) two weeks after treatment with Juvederm with Lidocaine (either Ultra or Ultra Plus) in one nasolabial fold and Juvederm (either Ultra or Ultra Plus) in the other nasolabial fold. (NCT00653861)
Timeframe: 2 weeks
| Intervention | Units on a scale (Mean) | |
|---|---|---|
| Improvement using Juvederm Ultra | Improvement using Juvederm Ultra Plus | |
| Juvéderm Lidocaine NLFs | 1.6 | 1.8 |
| Juvéderm NLFs | 1.6 | 1.8 |
"Measure of distance (mm) from the left (no pain) on the 100-mm visual analog scale (VAS - reflecting magnitude of pain) recorded at time immediately after osmotic dilator placement. 0 mm=No Pain and 100 mm= worst possible pain. A higher score indicates a higher level of pain." (NCT02354092)
Timeframe: Within 5 minutes of PCB or sham procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Sham Group | 46 |
| Paracervical Block Group | 32 |
"Measure of distance (mm) from the left (no pain) on the 100-mm visual analog scale (VAS - reflecting magnitude of pain) recorded 15 minutes after osmotic dilator placement. mm=No Pain and 100 mm= worst possible pain. A higher mean score indicates a higher level of pain experienced at this time point." (NCT02354092)
Timeframe: 15 minutes after dilator placement
| Intervention | units on a scale (Mean) |
|---|---|
| Sham Group | 42 |
| Paracervical Block Group | 35 |
"Measure of distance (mm) from the left (no pain) on the 100-mm visual analog scale (VAS - reflecting magnitude of pain) recorded at time immediately after last injection for paracervical block OR script for sham injection. 0 mm=No Pain and 100 mm= worst possible pain. A higher score indicates a higher level of pain." (NCT02354092)
Timeframe: Within 5 minutes after baseline
| Intervention | units on a scale (Mean) |
|---|---|
| Sham Group | 19 |
| Paracervical Block Group | 39 |
"Measure of distance (mm) from the left (no pain) on the 100-mm visual analog scale (VAS - reflecting magnitude of pain) of pain recorded at baseline prior to the paracervical block or sham block procedure. 0 mm=No Pain and 100 mm= worst possible pain. A higher score indicates a higher level of pain." (NCT02354092)
Timeframe: Baseline, just prior to PCB or sham procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Sham Group | 4 |
| Paracervical Block Group | 19 |
fever, chills, vomiting, heavy bleeding/clots (collected without regard to the specific event) (NCT00617097)
Timeframe: end of study (upon discharge from facility after procedure)
| Intervention | participants (Number) |
|---|---|
| Paracervical Block With Lidocaine | 3 |
| Paracervical Block With Ketorolac and Lidocaine | 0 |
100-mm Visual Analogue Scale -- minimum: 0 mm (lower satisfaction), maximum: 100 mm (greater satisfaction) (NCT00617097)
Timeframe: end of study (prior to clinic discharge)
| Intervention | mm (Mean) |
|---|---|
| Paracervical Block With Lidocaine | 62.9 |
| Paracervical Block With Ketorolac and Lidocaine | 63.6 |
(NCT00617097)
Timeframe: end of study
| Intervention | participants (Number) | |
|---|---|---|
| minor | serious | |
| Paracervical Block With Ketorolac and Lidocaine | 1 | 2 |
| Paracervical Block With Lidocaine | 1 | 0 |
"100-mm Visual Analogue Scale (VAS) during specific time intervals of D&C procedure: minimum: 0 mm (less pain); maximum: 100 mm (more pain)~Time intervals include: basline expected level of pain during procedure, after speculum insertion, at paracervical block injection, after dilation, end of procedure, and 30 minutes after procedure." (NCT00617097)
Timeframe: Baseline, Speculum Insertion, at Paracervical block injection, After dilation, End of procedure, 30 minutes after procedure
| Intervention | mm (Mean) | |||||
|---|---|---|---|---|---|---|
| expected level of pain during procedure | after speculum insertion | during paracervical block administration | after cervical dilation | immediately after procedure | 30 min after procedure | |
| Paracervical Block With Ketorolac and Lidocaine | 51.7 | 32.7 | 46.0 | 59.8 | 64.3 | 17.6 |
| Paracervical Block With Lidocaine | 52.2 | 33.6 | 50.8 | 74.8 | 61.5 | 21.8 |
This used a visual analog scale from 0 (minimum) to 10 (maximum) that was measured as centimeters. A higher score would indicate more pain, therefore, a worse outcome. Pain was assessed at each step that could potentially elicit pain, specifically when there was direct physical manipulation. (NCT00811187)
Timeframe: During Procedure
| Intervention | Score on a scale (Mean) |
|---|---|
| Lidocaine Group | 4.15 |
| Saline Placebo Group | 3.38 |
Numeric rating scale (NRS) 0-10 : 0 (no pain) - 5 (moderate pain) - 10 (worst pain). Scores to be utilized after stream device applied and after intravenous catheter placement. (NCT01670487)
Timeframe: pain of intravenous catheter placement.
| Intervention | NRS (Mean) |
|---|---|
| Vapocoolant (Pain Ease Medium Stream) | 2.3 |
| Placebo (Nature's Tears) | 4.3 |
"Two treatment visits were required for bilateral, mandibular dental operative restorations. At each visit, local anesthetic was delivered to the right or left side of the dentition using one of the two anesthetic types. The administering operator stepped out of the room after each injection was completed, and the participant was asked by a trained research assistant to record a visual analog scale (VAS) pain score. The VAS was used to assess pain sensitivity, and utilizes a 100mm horizontal line, with scores ranging from 0 (no pain) to 100 (pain as bad as it can be)." (NCT01622296)
Timeframe: immediately after anesthetic injection
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Pain on inferior alveolar nerve block | Pain on long buccal nerve block | |
| Buffered Lidocaine | 33.1 | 9.8 |
| Lidocaine | 43 | 7.3 |
A secondary outcome includes a pharmacoeconomic analysis that will look specifically at the cost-savings of using one agent over the other and will take into account the daily time allocated to pharmacy technicians and pharmacists for compounding and verifying buffered lidocaine. The outcome data was measured and reported in a single value dollar amount per group, tallied over a 3 month period. The dollar amounts were estimated by adding up the costs of drug purchasing, technician compounding time, and pharmacist verifying time. Buffered lidocaine required both drug purchasing and compounding time, where the lidocaine and bacteriostatic normal saline required drug purchasing alone and labor costs were not taken into account. (NCT01759459)
Timeframe: 3 months
| Intervention | Dollars (Number) |
|---|---|
| Buffered Lidocaine Cost | 13400 |
| Lidocaine Cost | 9100 |
| Bacteriostatic Normal Saline Cost | 4840 |
The primary outcome measured in this study will be the level of pain reported, on a scale of 0 to 10, 0 being no pain at all and 10 being the worst pain ever felt, by the patient upon administration of the local anesthetic and upon insertion of the peripheral intravenous catheter. (NCT01759459)
Timeframe: Day 1
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 2.81 |
| Buffered Lidocaine | 1.64 |
| Bacteriostatic Normal Saline | 2.05 |
The primary outcome measured in this study will be the level of pain reported, on a scale of 0 to 10, 0 being no pain at all and 10 being the worst pain ever felt, by the patient upon administration of the local anesthetic and upon insertion of the peripheral intravenous catheter. (NCT01759459)
Timeframe: Baseline and day 1
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Average pain score following medication injection | Average pain score following IV inserti | |
| Bacteriostatic Normal Saline | 2.10 | 3.05 |
| Buffered Lidocaine | 1.6 | 1.81 |
| Lidocaine | 2.58 | 1.81 |
(NCT00651625)
Timeframe: during procedure, 2 weeks afterwards, and 6 months afterwards
| Intervention | participants (Number) |
|---|---|
| 1Conventional Syringe | 0 |
| 2RPD Syringe | 0 |
Aspirated fluid volume during procedure (NCT00651625)
Timeframe: during procedure
| Intervention | ml (Mean) |
|---|---|
| 1Conventional Syringe | 7.2 |
| 2RPD Syringe | 14.5 |
0-10 cm VAS pain scale at 2 weeks compared to 0-10 cm VAS pain scale at 0 weeks where 0= no pain, and 10 = the worst pain imaginable. The difference (2 week VAS-0 week VAS) is the primary outcome measure. (NCT00651625)
Timeframe: 2 weeks
| Intervention | cm (Mean) |
|---|---|
| 1Conventional Syringe | 5.2 |
| 2RPD Syringe | 6.2 |
"0- 10 cm visual analogue satisfaction scale (VASS)~0-10 cm VASS at 2 weeks compared to 0-10 cm VASS pain scale at 0 weeks where 0= completely dissatisfied, and 10 = completely satsified. The difference (2 week VAS-0 week VAS) is the outcome measure" (NCT00651625)
Timeframe: during procedure
| Intervention | cm (Mean) |
|---|---|
| 1Conventional Syringe | 6.4 |
| 2RPD Syringe | 8.5 |
This secondary analysis looked at provider perception of patient maximum pain during IUD insertion This was not done per intervention because we were looking at the accuracy of the provider's assesment of the patient's pain, which is not dependent on intervention. The provider was blinded to the intervention so that would not have influenced results. (NCT01214161)
Timeframe: during IUD insertion
| Intervention | units on a 100 mm visual analogue scale (Mean) |
|---|---|
| Participants | 63.8 |
| Providers | 35.3 |
(NCT01214161)
Timeframe: During IUD insertion
| Intervention | participants (Number) | ||
|---|---|---|---|
| Nausea | Vomiting | Dizziness | |
| Lidocaine Gel | 8 | 0 | 9 |
| Placebo Gel (Surgilube) | 4 | 0 | 12 |
Patient marked pain on a 100 mm visual analogue scale during the part of the IUD insertion procedure where the tenaculum was placed, the uterus was measured/sounded, the IUD was inserted into the uterus, and the speculum was removed. (NCT01214161)
Timeframe: During IUD insertion (see above description for which time points)
| Intervention | units on a 100 mm visual analogue scale (Mean) | |||
|---|---|---|---|---|
| Tenaculum placement | Uterine sounding | IUD insertion | Speculum removal | |
| Lidocaine Gel | 35.4 | 55.5 | 51.0 | 20 |
| Placebo Gel (Surgilube) | 34.3 | 51.6 | 50.9 | 20 |
A semi-structured interview guide(available in both English and Spanish) which was developed in consultation with an expert in qualitative methodology at the UNM Clinical & Translational Science Center (CTSC), and UNMH family planning experts, will be administered to all participants. The interview will incorporate the following domains of women's perceptions of the postplacental IUD insertion experience: decisional influence, experience during the procedure, decisional regret, prior knowledge/ awareness of the method and postpartum contraception in general. The interview will conclude with an overall patient satisfaction score measured on a five-point Likert scale: 1 = very dissatisfied, 2 = somewhat dissatisfied, 3 = neutral, 4 = somewhat satisfied, 5 = very satisfied. (NCT02312726)
Timeframe: Within 24-48 hours after vaginal delivery, prior to hospital discharge
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| Very Satified | Satisfied | Neutral | Dissatisfied | Very Dissatisfied | |
| Epidural Group | 12 | 0 | 0 | 0 | 0 |
| Non Epidural Group | 7 | 2 | 0 | 0 | 0 |
This is a 4-item ordinal pain scale which has been used for pain level assessment. When prompted, patients will be asked to indicate which level of pain most accurately represents their pain level; 0 = No pain, 1 = Mild pain, 2 = Moderate pain, 3 = Severe pain. (NCT02312726)
Timeframe: Immediately prior to and within 5 minutes after IUD insertion following vaginal delivery. Women who undergo a postpartum interview will be asked to perform a recal VRS pain assessment
| Intervention | participants (Number) | |||||
|---|---|---|---|---|---|---|
| No Pain or Mild Pain before IUD placement | No Pain or Mild Pain during IUD placement | No Pain or Mild Pain at recall | Moderate Pain or Severe Pain before IUD placement | Moderate Pain or Severe Pain during IUD placement | Moderate Pain or Severe Pain at recall | |
| Epidural Group | 34 | 32 | 12 | 2 | 4 | 0 |
| Non Epidural Group | 15 | 16 | 6 | 15 | 14 | 3 |
This is a validated instrument used extensively in the assessment of acute pain. When prompted, patients will be asked to mark the continuous 100 mm VAS line at the point which most accurately represents their pain level; 0 = no pain, 100 = pain as bad as it could be. (NCT02312726)
Timeframe: Immediately prior to and within 5 minutes after IUD insertion following vaginal delivery; women who undergo a postpartum interview will be asked to perform a recall VAS pain assessment
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Pre-insertion | Procedure | Recall | |
| Epidural Group | 10.6 | 10.9 | 5.4 |
| Non Epidural Group | 35.3 | 41.4 | 28.6 |
The provider who inserts the IUD will be asked to complete a 4-item Likert scale rating perceived difficultly of insertion: 1 = easy; 2 = somewhat easy; 3 = somewhat difficult, 4 = difficult. (NCT02312726)
Timeframe: Within 5 minutes following postpartum IUD insertion
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| Easy | Somewhat easy | Somewhat difficult | Difficult | Unanswered | |
| Epidural Group | 19 | 16 | 3 | 0 | 0 |
| Non Epidural Group | 15 | 11 | 3 | 0 | 1 |
cry video recorded and measured after needle stick until pt stopped crying (NCT01224431)
Timeframe: On average the first hour in the emergency department; from needle stick to end of lumbar puncture
| Intervention | seconds (Mean) |
|---|---|
| Buffered Lidocaine J-tip | 38.53 |
| Normal Saline J-tip | 48.76 |
Pain scores at time of needle insertion using neonatal facial coding score. The scale has five components; cry, brow bulge, eye squeeze; nasolabial fold and open month. Each component is either present or absent, with a value of 0 or 1 given. Minimum score of 0 and a maximum score of 5 possible (NCT01224431)
Timeframe: on average the first hour in emergency department at 4 time points during entire lumbar puncture procedure.
| Intervention | units on scale, 0-5 (Mean) |
|---|---|
| Needleless Injection of Buffered Lidocaine | 4.0 |
| Normal Saline Via Needleless Injection | 4.8 |
Members of both study groups completed the Visual Analog Scale (VAS) pain assessment both prior for anticipated pain and after injection for actual pain; these recorded scores were the primary study endpoint and were later compared to determine the difference in anticipated pain versus actual pain experienced. The VAS ranges from 0-10, where 0 is no pain and 10 is worst possible pain. The outcome measure is the mean anticipated pain minus the actual pain experienced. (NCT02084706)
Timeframe: Our outcome measure was collected within the 60 seconds before and following the steroid injection.
| Intervention | units on a scale (Mean) |
|---|---|
| Triamcinolone (20 g) and 2% Lidocaine Injection Over A1 Pulley | 1.6 |
| J-tip Lidocaine Administration, Then Steroid Injection | 2.8 |
Patient break-through narcotic requirements in morphine equivalents are 0.2 mg of dilaudid = 1 mg of morphine, iv., used during and after VAC dressing change. (NCT01126359)
Timeframe: 20 minutes
| Intervention | Narcotic Requirements (mg) (Mean) | |||
|---|---|---|---|---|
| During VAC change | 5 min post-VAC change | 10 min post VAC change | 20 min post VAC change | |
| Lidocaine | 1.3 | 0.8 | 0.2 | 0.0 |
| Lidocaine Minus Placebo-Saline Difference | -1.7 | -0.4 | -0.2 | -0.3 |
| Placebo-Saline | 3.0 | 1.1 | 0.4 | 0.3 |
Visial Analog Pain Scores (VAS) range from 0 (no pain) - 10 (worst pain ever). Visial Analog Pain Scores are determined at each pain measurement time point (during/after VAC dressing removal). (NCT01126359)
Timeframe: 20 minutes
| Intervention | Visial Analog Pain Score (VAS) (Mean) | |||
|---|---|---|---|---|
| During VAC change | 5 min post-VAC change | 10 min post VAC change | 20 min post VAC change | |
| Lidocaine | 6.5 | 4.4 | 3.2 | 2.4 |
| Lidocaine Minus Placebo-Saline Difference | -2.4 | -2.0 | -1.5 | -1.8 |
| Placebo-Saline | 8.9 | 6.4 | 4.7 | 4.2 |
Parent score 1-10 (1 representing no pain and 10 representing extreme pain) FLACC (Face, Legs, Activity, Cry, Consolability) Score 0-10 (at baseline and post injection) (0 representing no pain and 10 representing extreme pain) Change in FLACC score (NCT00484393)
Timeframe: 2 visits, 1 month apart
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| Parent score | FLACC at baseline | FLACC post injection | Change in FLACC | |
| Placebo | 7.3 | 1.6 | 9.3 | 7.7 |
| Tetracaine | 7.3 | 1.7 | 8.4 | 6.7 |
(NCT03408171)
Timeframe: Number Analyzed
| Intervention | mm (Median) |
|---|---|
| 19-gauge FNA Needle | 32.3 |
| 19-gauge FNB Needle | 30.2 |
Number of portal triads (PT) in the specimen. (NCT03408171)
Timeframe: 3-5 days
| Intervention | Portal Triads (Mean) |
|---|---|
| 19-gauge FNA Needle | 18.1 |
| 19-gauge FNB Needle | 42.6 |
Number of portal triads (PT) in the specimen. (NCT03408171)
Timeframe: 3-5 days
| Intervention | Complete number of portal triads (Median) |
|---|---|
| 19-gauge FNA Needle | 16.5 |
| 19-gauge FNB Needle | 38 |
Post-processing Aggregate specimen length (ASL) measured in centimeter (NCT03408171)
Timeframe: 3-5 days
| Intervention | centimeter (Mean) |
|---|---|
| 19-gauge FNA Needle | 11.4 |
| 19-gauge FNB Needle | 15.32 |
Post-processing Length of the longest piece (LLP) measured in centimeter (NCT03408171)
Timeframe: 3-5 days
| Intervention | centimeter (Mean) |
|---|---|
| 19-gauge FNA Needle | 1.05 |
| 19-gauge FNB Needle | 1.78 |
Pre-processing Aggregate specimen length (ASL) measured in centimeter (NCT03408171)
Timeframe: 3-5 days
| Intervention | centimeter (Mean) |
|---|---|
| 19-gauge FNA Needle | 10.89 |
| 19-gauge FNB Needle | 15.78 |
Pre-processing Length of the longest piece (LLP) measured in centimeter (NCT03408171)
Timeframe: up to 5 days
| Intervention | centimeter (Mean) |
|---|---|
| 19-gauge FNA Needle | 1.47 |
| 19-gauge FNB Needle | 2.09 |
Number of cases for which a histologic diagnosis could be made based upon the amount of tissue obtained with the needle. (NCT03408171)
Timeframe: 3-5 days
| Intervention | Participants (Count of Participants) |
|---|---|
| 19-gauge FNA Needle | 20 |
| 19-gauge FNB Needle | 20 |
No. of fragments > 9 mm, mean (SD) Pre-processing Post-processing (NCT03408171)
Timeframe: 3-5 days
| Intervention | Number of Fragments (Mean) | |
|---|---|---|
| Pre-processing | Post-processing | |
| 19-gauge FNA Needle | 3.5 | 1.1 |
| 19-gauge FNB Needle | 7.7 | 4.8 |
"Length of all the tissue (centimeters) by adding the sum of all pieces Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | cm for portal tracts of specimens (Mean) |
|---|---|
| 19 Gauge FNA | 76.5 |
| 22 Gauge FNB | 66.9 |
"length of the longest tissue biopsy piece (centimeters) as measured by pathology Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | mean cm for portal tracts of specimens (Mean) |
|---|---|
| 19 Gauge FNA | 13.2 |
| 22 Gauge FNB | 10.8 |
"Number of portal tracts (PT) in the specimen (total) under histologic examination Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | mean portal tracts (Mean) |
|---|---|
| 19 Gauge FNA | 7.4 |
| 22 Gauge FNB | 6.1 |
"Defined by total portal structures > 5 or length of the longest piece > 15 mm) Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | specimens (Number) |
|---|---|
| 19 Gauge FNA | 17 |
| 22 Gauge FNB | 14 |
"Patient requiring visit to healthcare center (emergency room, hospital, call to service) within time 7 days Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 Days
| Intervention | Participants (Count of Participants) |
|---|---|
| Total Population | 1 |
"Pain using Likert score 0-10 (10 worst) Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 1 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Total Population | 0 |
"Pain using Likert score 0-10 (10 worst) Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Total Population | 1 |
"Patient with blood visible from patient's mouth, rectum with a 2 gram drop in hemoglobin Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Total Population | 0 |
"Presence of visible clots in specimen (yes/no) Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: Day of Procedure
| Intervention | specimens (Number) |
|---|---|
| 19 Gauge FNA | 4 |
| 22 Gauge FNB | 1 |
"Presence of a visible core specimen (yes/no) Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: Day of Procedure
| Intervention | specimens (Number) |
|---|---|
| 19 Gauge FNA | 20 |
| 22 Gauge FNB | 19 |
Time of first instance of a bowel movement will be measured as the number of days post operatively for bowel function to return. (NCT02623803)
Timeframe: up to 3 weeks postoperatively
| Intervention | days (Mean) |
|---|---|
| Treatment Group | 5.8 |
| Control Group | 5.2 |
Time of first instance of flatus will be measured as the number of days post operatively for bowel function to return. (NCT02623803)
Timeframe: up to 3 weeks postoperatively
| Intervention | days (Mean) |
|---|---|
| Treatment Group | 3.9 |
| Control Group | 2.7 |
Total opioid consumption in PACU converted to morphine equivalents in mg. (NCT02623803)
Timeframe: up to 4 hours post-operatively
| Intervention | mg (Mean) |
|---|---|
| Treatment Group | 3.9 |
| Control Group | 6.7 |
Overall pain will be measured 30 minutes after arrival at the post-operative care unit (PACU) using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: 30 minutes after arrival to PACU
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 3.3 |
| Control Group | 5.3 |
Overall pain will be measured approximately 12 hours post-operatively using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: approximately 12 hours post-operatively
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 4.4 |
| Control Group | 5.4 |
Overall pain will be measured on post-operative day 1 at 1 pm using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: post-operative day 1 at 1 pm
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 4.8 |
| Control Group | 4.8 |
Overall pain will be measured on post-operative day 1 at 1am using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: post-operative day 1 at 1am
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 5.1 |
| Control Group | 5.5 |
Overall pain will be measured upon arrival at the post-operative care unit (PACU) using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: baseline - arrival at the PACU
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 1.6 |
| Control Group | 2.7 |
Pain at rest will be measured 30 minutes after arrival at the post-operative care unit (PACU) using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: 30 minutes after arrival to PACU
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 3.3 |
| Control Group | 5.1 |
Pain at rest will be measured approximately 12 hours post-operatively using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: approximately 12 hours post-operatively
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 4.0 |
| Control Group | 5.0 |
Pain at rest will be measured at post-operative day 1 at 1 pm using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: post-operative day 1 at 1 pm
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 4.0 |
| Control Group | 4.8 |
Pain at rest will be measured on post-operative day 1 at 1 am using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: post-operative day 1 at 1 am
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 4.0 |
| Control Group | 4.6 |
Pain will be measured at rest upon arrival at the post-operative care unit (PACU) using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: baseline - arrival at the PACU
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 2.1 |
| Control Group | 2.6 |
Pain with coughing will be measured 30 minutes after arrival at the post-operative care unit (PACU) using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: 30 minutes after arrival to PACU
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 4.3 |
| Control Group | 5.8 |
Pain with coughing will be measured approximately 12 hours post-operatively using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: approximately 12 hours post-operatively
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 4.7 |
| Control Group | 7.6 |
Pain with coughing will be measured on post-operative day 1 at 1 am using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: post-operative day 1 at 1 am
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 5.4 |
| Control Group | 7.1 |
Pain with coughing will be measured on post-operative day 1 at 1 pm using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: post-operative day 1 at 1 pm
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 5.4 |
| Control Group | 5.8 |
Pain with coughing will be measured upon arrival at the post-operative care unit (PACU) using numerical rating scale (NSR). Subjects will rate their pain after surgery on a scale from 0 to 10, where 0 is no pain and 10 is the worst pain imaginable. (NCT02623803)
Timeframe: baseline - arrival at the PACU
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Group | 2.3 |
| Control Group | 2.5 |
Total amount of opioids converted to morphine equivalents in mg administered in the first 24 hours after surgery. (NCT02623803)
Timeframe: up to 24 hours post-operatively
| Intervention | mg (Mean) |
|---|---|
| Treatment Group | 7.4 |
| Control Group | 7.9 |
This questionnaire is a short 15 question form that measures the quality of a subject's postoperative recovery. The scale is ranked from 0 to 10, where 0 is a poor response and 10 is an excellent response. (NCT02623803)
Timeframe: Day 15 post-operatively
| Intervention | score on a scale (Mean) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Able to breathe easily | Been able to enjoy food | Feeling rested | Have had a good sleep | Able to look after personal toliet and hygiene | Able to communicate with family or friends | Getting support from hospital doctors and nurse | Able to return to work or usual home activities | Feeling comfortable and in control | Having a feeling of general well-being | Moderate pain | Severe pain | Nausea or vomiting | Feeling worried or anxious | Feeling sad or depressed | |
| Control Group | 8.7 | 5.4 | 6.0 | 6.6 | 8.8 | 9.3 | 9.5 | 4.9 | 6.7 | 6.7 | 6.6 | 8.8 | 8.2 | 7.6 | 7.8 |
| Treatment Group | 9.1 | 6.2 | 7.2 | 7.1 | 9.2 | 9.6 | 8.8 | 5.4 | 7.1 | 7.5 | 7.9 | 9.4 | 8.6 | 7.7 | 8.4 |
The success of lumbar puncture was defined as obtaining Cerebrospinal fluid (CSF) on the first attempt and <1000 Red Blood Cells/millimeter cubed (NCT01628874)
Timeframe: Immediately following lumbar puncture
| Intervention | Participants (Count of Participants) |
|---|---|
| EMLA Cream, Then Placebo Via J-Tip | 8 |
| Placebo Cream, Then Lidocaine Via J-Tip | 16 |
The pain score was assessed using the 5-point Neonatal Coding System (NFCS) on a scale of 0-5, with 0 indicating no pain and 5 the highest level of pain. (NCT01628874)
Timeframe: At Needle Insertion
| Intervention | score on a scale (Median) |
|---|---|
| EMLA Cream, Then Placebo Via J-Tip | 5 |
| Placebo Cream, Then Lidocaine Via J-Tip | 5 |
The pain score was assessed using the 5-point Neonatal Coding System (NFCS) on a scale of 0-5, with 0 indicating no pain and 5 the highest level of pain. (NCT01628874)
Timeframe: At time J-TIP is used
| Intervention | score on a scale (Median) |
|---|---|
| EMLA Cream, Then Placebo Via J-Tip | 5 |
| Placebo Cream, Then Lidocaine Via J-Tip | 5 |
The pain score was assessed using the 5-point Neonatal Coding System (NFCS) on a scale of 0-5, with 0 indicating no pain and 5 the highest level of pain. (NCT01628874)
Timeframe: Immediately Post-Procedure
| Intervention | score on a scale (Median) |
|---|---|
| EMLA Cream, Then Placebo Via J-Tip | 0 |
| Placebo Cream, Then Lidocaine Via J-Tip | 0 |
Heart rate was measured at 5 points in time (pre-procedure, application of J-Tip, at LP needle insertion, while the needle is in place, and post-procedure) and was compared for significant differences (NCT01628874)
Timeframe: At 5 specific points during the procedure
| Intervention | Beats per Minute (Mean) | ||||
|---|---|---|---|---|---|
| Pre-procedure | J-Tip application | Needle insertion | Needle in place | Post-procedure | |
| EMLA Cream, Then Placebo Via J-Tip | 154 | 160 | 170 | 172 | 157 |
| Placebo Cream, Then Lidocaine Via J-Tip | 156 | 167 | 169 | 178 | 159 |
"Efficacy is defined as:~The patient does not have unpleasant recall of the procedure.~The patient did not experience sedation-related adverse events resulting in abandonment of the procedure or a permanent complication or an unplanned admission to the hospital or prolonged emergency department (ED) observation~The patient did not actively resist or require physical restraint for completion of the procedure. The need for minimal redirection of movements should not be considered as active resistance or physical restraint.~The procedure was successful" (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
| Intervention | participants (Number) |
|---|---|
| Ketamine Alone | 97 |
| Ketamine Co-Administered With Propofol | 81 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
| Intervention | units on a scale (Median) |
|---|---|
| Ketamine Alone | 10 |
| Ketamine Co-Administered With Propofol | 8 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
| Intervention | units on a scale (1-10) (Median) |
|---|---|
| Ketamine Alone | 10 |
| Ketamine Co-Administered With Propofol | 10 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
| Intervention | units on a scale (Median) |
|---|---|
| Ketamine Alone | 9 |
| Ketamine Co-Administered With Propofol | 8 |
Time until the patient has a Vancouver Sedation Recovery Scale Score of 18 or greater. (NCT01387139)
Timeframe: Once Vancouver Sedation Recovery Scale Score reaches 18 or greater, on average less than 1 hour
| Intervention | minutes (Median) |
|---|---|
| Ketamine Alone | 44 |
| Ketamine Co-Administered With Propofol | 43.5 |
We will record all adverse events during the sedation, and then perform a follow-up call to determine if any additional adverse events occured after discharge. (NCT01387139)
Timeframe: From enrollment through completion of follow-up, up to 7 days
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| Respiratory depression | Cardiovascular event | vomiting/retching | Unpleasant recovery reaction | |
| Ketamine Alone | 12 | 1 | 21 | 4 |
| Ketamine Co-Administered With Propofol | 15 | 0 | 18 | 2 |
The cumulative dose of oxaliplatin received over the course (up to 12 cycles) of mFOLFOX6 treatment regimen. It corresponds to the absolute summed up quantity of Oxaliplatin administered to the patient over time. There is no range for this measure. Since this is a dose-limiting neuropathy prevention study, the higher value can be interpreted as better outcome. (NCT03254394)
Timeframe: 24 weeks
| Intervention | mg (Mean) |
|---|---|
| Placebo + FOLFOX | 1161.8 |
| Lidocaine + FOLFOX | 1294.8 |
"The intensity of cold pain and cold unpleasantness is evaluated separately, assessed daily on a 0-10 scale, upon holding a pre-cooled (~8°C) metal cylinder for 10 seconds. the area under the curve of cold pain and cold unpleasantness vs time is calculated per chemotherapy cycle (every two weeks) and serves as a primary outcome measure.~For intervention (lidocaine+FOLFOX) and control (placebo+FOLFOX) groups, the average of cold pain AUC and cold unpleasantness AUC over 7 cycles was calculated. The average AUCs over 7 cycles were compared between study arms.~The AUC is measured as a score on a 0-10 scale multiplied by 14 days and may range between 0 and 140. Higher AUC values represent more intense cold pain/unpleasantness." (NCT03254394)
Timeframe: 14 weeks
| Intervention | score on a scale*days (Mean) | |
|---|---|---|
| pain AUC | unpleasantness AUC | |
| Lidocaine + FOLFOX | 9.5 | 25.4 |
| Placebo + FOLFOX | 16.4 | 33.1 |
Changes in Neuropathic Pain Symptom Inventory (NPSI) descriptors of neuropathic pain over time from baseline to cycle 3(6 weeks), cycle 6 (12 weeks), and the last follow-up (34-36 weeks). The total NPSI score ranges from 0 to 100; a higher NPSI total score represents a worse neuropathy outcome. The changes in scores from baseline are compared between study arms. (NCT03254394)
Timeframe: 6 weeks, 12 weeks, 34-36 weeks
| Intervention | score on a scale (Median) | ||
|---|---|---|---|
| 6 weeks visit | 12 weeks visit | last follow-up visit | |
| Lidocaine + FOLFOX | 0 | 0 | 13.5 |
| Placebo + FOLFOX | 0 | 0 | 3.0 |
"Change in CIPN (Chemotherapy-induced peripheral Neuropathy) score (on EORTC QLQ-CIPN20 tool ) from baseline to the Cycle 6 (12 weeks), and from baseline to last follow-up (34-36 weeks). EORTC QLQ-CIPN20 ranges from 0 (no symptoms) to 100 (worst symptoms). A higher score represents worse neuropathy. The changes in scores are compared between study arms.~EORTC QLQ-CIPN20 tool is a quality of life questionnaire (QLQ) from the European Organization for Research and Treatment of Cancer (EORTC) for evaluation of CIPN." (NCT03254394)
Timeframe: 12 weeks and 34-36 weeks
| Intervention | score on a scale (Median) | |
|---|---|---|
| 12 | 34-36 weeks | |
| Lidocaine + FOLFOX | 4 | 37.0 |
| Placebo + FOLFOX | 2 | 17.0 |
To assess need for additional intraoperative and/or postoperative pain medication (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydrocodone/Acetaminophen | 0 |
| Placebo | 0 |
To determine whether HC/APAP, given in addition to a standard regimen of ibuprofen, lorazepam, and PCB, affects patient pain perception at the time of uterine aspiration, as measured by distance (mm) from the left of the 100 mm visual analog scale (VAS). The number 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: At time of uterine aspiration (baseline)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 65.7 |
| Placebo | 63.1 |
Distance (mm) from the left of the 100 mm VAS scale (VAS anchors: 0 = none, 100 mm = worst imaginable) recorded after cervical dilation (NCT01330459)
Timeframe: During procedure (approximately 45-90 min after hydrocodone/acetaminophen or placebo, and within 5 minutes of procedure starting)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 47.2 |
| Placebo | 43.9 |
To assess whether HC/APAP is associated with nausea, measured on the 100 mm VAS, recorded 30 minutes postoperatively. VAS anchors: 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 19.4 |
| Placebo | 11.4 |
Distance (mm) from the left of the 100 mm VAS (VAS anchors: 0 = unsatisfied, 100 mm = very satisfied) recorded 30 minutes after completion of the procedure. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 74.8 |
| Placebo | 67.3 |
Pain is measured using the Pain Numeric Rating Scale (NRS), which ranges from 0 to 10 with higher scores indicating greater pain. This measure is recorded at baseline (0 weeks) and 8 weeks. The change in pain between these two time points (i.e., the difference score) is compared between the two groups. (NCT02044991)
Timeframe: 8 weeks
| Intervention | change score on the NRS pain scale (Median) |
|---|---|
| Treatment | -3 |
Disability is measured at baseline (0 weeks) and week 8 using the Oswestry Disability Index (ODI), which is a measure of low back pain that ranges from 0 points to 100 with higher scores indicating greater disability. The change in disability between these two time points (i.e., the difference score) is compared between the two groups. (NCT02044991)
Timeframe: 8 weeks
| Intervention | change score on the ODI scale (Median) |
|---|---|
| Treatment | -15.25 |
Pelvic functioning is measured at baseline (0 weeks) and week 8 using the Pelvic Girdle Questionnaire (PGQ), which ranges from 0 to 100 points with higher scores revealing greater pelvic girdle pain. The change in pelvic functioning between these two time points (i.e., the difference score) is compared between the two groups. (NCT02044991)
Timeframe: 8 weeks
| Intervention | change score on the PGQ scale (Median) |
|---|---|
| Treatment | -35.5 |
NRS - numerical rating scale, 0-10 is the range, and higher scores are worse frequency (NCT00427648)
Timeframe: 6 weeks
| Intervention | score on a 0-10 scale (Median) |
|---|---|
| 1/Xylocaine | 4 |
| 2/Normal Saline | 4 |
This is based on retrograde infusion of sterile water into the bladder using a catheter, the maximum tolerated volume serving to define how much distension a woman can tolerate. (NCT00427648)
Timeframe: 6 weeks
| Intervention | mL (Median) |
|---|---|
| 1/Xylocaine | 316 |
| 2/Normal Saline | 275 |
This is patient overall assessment of change in overactive bladder symptoms after treatment. 0% is no change, 100% is total resolution of symptoms (NCT00427648)
Timeframe: 6 weeks
| Intervention | percent improvement (Median) |
|---|---|
| 1/Xylocaine | 40 |
| 2/Normal Saline | 10 |
(NCT00427648)
Timeframe: 6 weeks
| Intervention | voids/day (Median) |
|---|---|
| 1/Active | 9.5 |
| 2/Placebo | 9 |
(NCT00427648)
Timeframe: 12 months
| Intervention | voids/day (Median) |
|---|---|
| 1/Xylocaine | 7 |
| 2/Normal Saline | 8 |
OAB-q SS is a 7 item overactive bladder symptom bother sub scale, ranging from 0-100, higher scores mean worse outcome for bother (NCT00427648)
Timeframe: 6 weeks
| Intervention | score on a scale (Median) |
|---|---|
| 1/Xylocaine | 15 |
| 2/Normal Saline | 28 |
SF-12 physical is an abbreviated version of the SF-36 a widely used, general health care quality of life instrument. Scores range from 0-100, and higher scores are better outcomes. (NCT00427648)
Timeframe: 6 weeks
| Intervention | score on scale (Median) |
|---|---|
| 1/Xylocaine | 49 |
| 2/Normal Saline | 56 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at tourniquet placement. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: before venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 41 | 6 | 2 | 1 | 0 | 0 |
| Synera Patch | 37 | 6 | 5 | 1 | 1 | 0 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain participants were experiencing 5 minutes after the venipuncture was completed. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: 5 minutes post venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 45 | 3 | 1 | 1 | 0 | 0 |
| Synera Patch | 45 | 4 | 1 | 0 | 0 | 0 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at needle insertion. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: during needle insertion
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 32 | 14 | 2 | 2 | 0 | 0 |
| Synera Patch | 25 | 12 | 9 | 2 | 2 | 0 |
The Numerical Rating Scale (NRS) is a 6-point rating scale where 0= no pain and 5 = worst pain. Parents reported their own subjective evaluation of participants pain level. Each participant had only one parental assessment. Total number of parental assessment for each pain level on the 6-point NRS is reported as total number of participants experiencing that pain level. (NCT00530803)
Timeframe: immediately after venipuncture is completed
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| number of participants with NRS=0 (no pain) | number of participants with NRS=1 | number of participants with NRS=2 | number of participants with NRS=3 | number of participants with NRS=4 | number of participants with NRS=5 | |
| EMLA Cream | 42 | 6 | 1 | 1 | 0 | 0 |
| Synera Patch | 41 | 5 | 1 | 2 | 0 | 1 |
"Participants were asked to report their level of pain using a 6-point Wong-Baker FACES Pain Rating Scale ranging from 0, no pain, to 5, the most pain you can have. The Wong-Baker FACES Pain Rating Scale is a validated tool for measuring pain in patients as young as 3 years old. A FACES pain score less than or equal to 2 is considered no pain to mild pain, and is clinically acceptable. Studies have shown average FACES pain scores for children receiving vascular access with placebo to be 2.2 to 3.5." (NCT00530803)
Timeframe: immediately after completion of venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants with FACES Score = 0 (No pain) | Participants with FACES Score = 1 | Participants with FACES Score = 2 | Participants with FACES Score = 3 | Participants with FACES Score = 4 | Participants with FACES Score = 5 | |
| EMLA Cream | 42 | 6 | 2 | 0 | 0 | 0 |
| Synera Patch | 38 | 8 | 3 | 1 | 0 | 0 |
"Mean change from baseline. Participants are asked Taking into account your pain level and how it affects your life, are you feeling better, the same or worse than when you started treatment? and then to quantify the magnitude of the change. with the 7-Point guy Farrar which measures the global treatment effect from with scale from 0 to 6, higher score indicates worse outcomes." (NCT02736890)
Timeframe: up to 12 weeks post-injection, for a total of 24 weeks from baseline
| Intervention | score on a scale (Mean) | |||||||
|---|---|---|---|---|---|---|---|---|
| 2 week post injection | 4 week post injection | 8 week post injection | 12 week post injection | crossover 2 week follow up | crossover 4 week follow up | crossover 8 week follow up | crossover 12 week follow up | |
| Botulinum Toxin A Then Placebo | 2.2 | 2.4 | 2 | 2 | 0 | 0 | 0 | 0 |
| Placebo Then Botulinum Toxin A | 0.3 | 0.3 | 0 | 0 | 5 | 5 | 3 | 1 |
The International Basic Pain Dataset is an assessment tool which includes several components including: location of pain, temporal qualities of the pain, type of pain, pain interference measures of activity, sleep, and mood. It has been shown to be valid in an interview/self -report format. The pain affecting day-to-day activities subset of the dataset is scored is from 0 to 10, with higher score indicating less favorable outcomes. (NCT02736890)
Timeframe: up to 12 weeks post-injection, for a total of 24 weeks from baseline
| Intervention | units on a scale (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | 2 week post injection | 4 week post injection | 8 week post injection | 12 week post injection | crossover 2 week follow up | crossover 4 week follow up | crossover 8 week follow up | crossover 12 week follow up | |
| Botulinum Toxin A Then Placebo | 4.2 | 5.4 | 5 | 5 | 4.8 | 7 | 6.7 | 7 | 6.7 |
| Placebo Then Botulinum Toxin A | 5.3 | 2.7 | 2.7 | 2.7 | 2.7 | 2 | 3 | 4 | 5 |
The International Basic Pain Dataset is an assessment tool which includes several components including: location of pain, temporal qualities of the pain, type of pain, pain interference measures of activity, sleep, and mood. It has been shown to be valid in an interview/self -report format. The pain affecting mood subset of the dataset is scored is from 0 to 10, with higher score indicating less favorable outcomes. (NCT02736890)
Timeframe: up to 12 weeks post-injection, for a total of 24 weeks from baseline
| Intervention | units on a scale (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | 2 week post injection | 4 week post injection | 8 week post injection | 12 week post injection | crossover 2 week follow up | crossover 4 week follow up | crossover 8 week follow up | crossover 12 week follow up | |
| Botulinum Toxin A Then Placebo | 5.6 | 6.6 | 5.8 | 5.2 | 5.6 | 7 | 7 | 7.3 | 6.7 |
| Placebo Then Botulinum Toxin A | 5.7 | 2.7 | 2.7 | 4.3 | 5.7 | 2 | 3 | 4 | 7 |
The International Basic Pain Dataset is an assessment tool which includes several components including: location of pain, temporal qualities of the pain, type of pain, pain interference measures of activity, sleep, and mood. It has been shown to be valid in an interview/self -report format. The pain affecting sleep subset of the dataset is scored is from 0 to 10, with higher score indicating less favorable outcomes. (NCT02736890)
Timeframe: up to 12 weeks post-injection, for a total of 24 weeks from baseline
| Intervention | units on a scale (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | 2 week post injection | 4 week post injection | 8 week post injection | 12 week post injection | crossover 2 week follow up | crossover 4 week follow up | crossover 8 week follow up | crossover 12 week follow up | |
| Botulinum Toxin A Then Placebo | 5.8 | 4.6 | 5 | 6 | 6.2 | 8 | 8 | 8 | 7.3 |
| Placebo Then Botulinum Toxin A | 6.7 | 4.7 | 3.3 | 6 | 6.7 | 1 | 3 | 4 | 5 |
Participant rated pain intensity from 0-10, with higher score indicating more pain (NCT02736890)
Timeframe: up to 12 weeks post-injection, for a total of 24 weeks from baseline
| Intervention | score on a scale (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| baseline | 2 week post injection | 4 week post injection | 8 week post injection | 12 week post injection | crossover 2 week follow up | crossover 4 week follow up | crossover 8 week follow up | crossover 12 week follow up | |
| Botulinum Toxin A Then Placebo | 7.6 | 6.4 | 5.6 | 5.6 | 5.6 | 8 | 8 | 6.7 | 8 |
| Placebo Then Botulinum Toxin A | 8 | 8 | 8 | 8 | 8 | 5 | 5 | 6 | 7 |
PGI measures activity affected by pain. Full score is 0 to 10000, with higher score indicating better function (NCT02736890)
Timeframe: up to 12 weeks post-injection, for a total of 24 weeks from baseline
| Intervention | score on a scale (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | 2 week post injection | 4 week post injection | 8 week post injection | 12 week post injection | crossover 2 week follow up | crossover 4 week follow up | crossover 8 week follow up | crossover 12 week follow up | |
| Botulinum Toxin A Then Placebo | 4250 | 5240 | 5219 | 3725 | 4330 | 3333.3 | 3333.3 | 3333.3 | 3333.3 |
| Placebo Then Botulinum Toxin A | 1500 | 1550 | 1825 | 2800 | 1800 | 3500 | 3750 | 3000 | 1500 |
"Patients will rate pain on a Heft-Parker visual analog scale during needle insertion, placement, and solution deposition phases of the anesthetic injection(s). Patients will also rate pain during the incision and dissection phases of the incision and drainage procedure. The number of millimeters along the scale are reported. No pain corresponded to 0 mm. Mild pain was defined as greater than 0 mm and less than or equal to 54 mm. Mild pain included the descriptors of faint, weak, and mild pain. Moderate pain was defined as greater than 54 mm and less than 114 mm and included the descriptor moderate. Severe pain was defined as equal to or greater than 114 mm up to and including 170 mm. Severe pain included the descriptors of strong, intense, and maximum possible." (NCT01981772)
Timeframe: during incision/drainage on Day 0
| Intervention | units on a scale (Mean) |
|---|---|
| Buffered Lidocaine | 69.3 |
| Nonbuffered Lidocaine | 59.2 |
"Patients will rate their level of satisfaction with the incision and drainage procedure using a visual analog scale. The scale ranges from not satisfied, to somewhat satisfied, to moderately satisfied, to completely satisfied. Not satisfied corresponded to 0 mm. Somewhat satisfied was defined as greater than 0 mm and less than or equal to 33 mm. Moderately satisfied was defined as greater than 33 mm and less than 66 mm. Completely satisfied was defined as equal to or greater than 66 mm. Measurements along the scale were collected and analyzed by randomization test." (NCT01981772)
Timeframe: immediately post-procedure on Day 0
| Intervention | units on a scale (Mean) |
|---|---|
| Buffered Lidocaine | 92.7 |
| Nonbuffered Lidocaine | 89.5 |
100 patients diagnosed with symptomatic irreversible pulpitis of a mandibular posterior tooth randomly received a conventional inferior alveolar nerve block (IAN) block using either 2.8 ml of 4% lidocaine with 1:100,000 epinephrine or 2.8 ml of 4% lidocaine with 1:100,000 epinephrine buffered with sodium bicarbonate in a double-blind manner. For the buffered solution, each cartridge was buffered with 8.4% sodium bicarbonate to produce a final concentration of 0.18 mEq/mL of sodium bicarbonate. Fifteen minutes after administration of the IAN block, profound lip numbness was confirmed and endodontic access was initiated. Success was determined as no or mild pain on access or instrumentation of the root canal. Higher numbers on the VAS are indicative of more pain and less success and the VAS scale ranged from 0 to 170 mm. (NCT01868776)
Timeframe: approximately 15 minutes after injection
| Intervention | percentage of participants (Number) |
|---|---|
| Buffered Lidocaine | 32 |
| Nonbuffered Lidocaine | 40 |
(NCT01868776)
Timeframe: pain at time of treatment (after buffered versus nonbuffered numbing solution) average of 15 minutes after injection
| Intervention | Participants (Count of Participants) |
|---|---|
| Buffered Lidocaine | 16 |
| Nonbuffered Lidocaine | 20 |
Additional Rescue Doses Per Hour Ratio is the number per hour of addition of rescue dose administrated with 10% of initial NMBAs dose. The formula is {(Addition number + 1 / Anesthetic time) x 60}. (NCT02495038)
Timeframe: Intraoperative, an average of 3 hours.
| Intervention | ratio (Mean) |
|---|---|
| Intubating Dose, Group I | 1.43455 |
| 10% Reduction of Combination of Esmeron® and Nimbex®, Group S | 1.21014 |
| 20% Reduction of Combination of Esmeron® and Nimbex®, Group L | 0.82128 |
Time from induction to recovery of anesthesia, asessed up to 3 hours. (NCT02495038)
Timeframe: Intraoperative, an average 4 hours.
| Intervention | Minute (Mean) |
|---|---|
| Intubating Dose, Group I | 163.0 |
| 10% Reduction of Combination of Esmeron® and Nimbex®, Group S | 159.9 |
| 20% Reduction of Combination of Esmeron® and Nimbex®, Group L | 161.4 |
"The BIS monitor provides a single dimensionless number, which ranges from 0 (equivalent to EEG silence) to 100. A BIS value between 40 and 60 indicates an appropriate level for general anesthesia, as recommended by the manufacturer.~Before induction of anesthesia, bispectral index was measured for baseline. And after injection of NMBAs, bispectral index was measured at 10 min." (NCT02495038)
Timeframe: Before and after induction of anesthesia, an average 10 min.
| Intervention | BIS score (Mean) |
|---|---|
| Intubating Dose, Group I | 46.0 |
| 10% Reduction of Combination of Esmeron® and Nimbex®, Group S | 46.1 |
| 20% Reduction of Combination of Esmeron® and Nimbex®, Group L | 44.3 |
"Before induction of anesthesia, body temperature was measured for baseline by oral temperature probe.~And after injection of NMBAs, non invasive blood pressure was measured at 10 min by esophageal temperature probe." (NCT02495038)
Timeframe: Before and after induction of anesthesia, an average 10 min.
| Intervention | Celcius degree (Mean) |
|---|---|
| Intubating Dose, Group I | 36.3 |
| 10% Reduction of Combination of Esmeron® and Nimbex®, Group S | 36.3 |
| 20% Reduction of Combination of Esmeron® and Nimbex®, Group L | 36.3 |
Time from administration of initial NMBAs to Train-of-four (TOF) ratio >25%, assessed up to 2 hours during general anesthesia. (NCT02495038)
Timeframe: Intraoperative, an average of 1 hours
| Intervention | Minute (Mean) |
|---|---|
| Intubating Dose, Group I | 51.3 |
| 10% Reduction of Combination of Esmeron® and Nimbex®, Group S | 47.9 |
| 20% Reduction of Combination of Esmeron® and Nimbex®, Group L | 39.4 |
Time from administration of initial NMBAs to Train-of-four (TOF) ratio=0, assessed up to 15 minutes during general anesthesia. (NCT02495038)
Timeframe: Intraoperative, an average of 5 minutes
| Intervention | Second (Mean) |
|---|---|
| Intubating Dose, Group I | 212.8 |
| 10% Reduction of Combination of Esmeron® and Nimbex®, Group S | 230.1 |
| 20% Reduction of Combination of Esmeron® and Nimbex®, Group L | 399.3 |
Time from skin incision to wound dressing assessed up to 8 hours. (NCT02495038)
Timeframe: Intraoperative, an average of 3 hours.
| Intervention | Minute (Mean) |
|---|---|
| Intubating Dose, Group I | 151.8 |
| 10% Reduction of Combination of Esmeron® and Nimbex®, Group S | 147.0 |
| 20% Reduction of Combination of Esmeron® and Nimbex®, Group L | 145.9 |
"Before induction of anesthesia, peripheral oxygen saturation was measured for baseline.~And after injection of NMBAs, peripheral oxygen saturation was measured at 10 min." (NCT02495038)
Timeframe: Before and after induction of anesthesia, an average 10 min.
| Intervention | Percentage (Mean) |
|---|---|
| Intubating Dose, Group I | 100 |
| 10% Reduction of Combination of Esmeron® and Nimbex®, Group S | 99.9 |
| 20% Reduction of Combination of Esmeron® and Nimbex®, Group L | 100 |
Time from TOF ratio 25% to 75%, assessed up to 1 hour during general anesthesia. (NCT02495038)
Timeframe: Intraoperative, an average of 20 minutes
| Intervention | Minute (Mean) |
|---|---|
| Intubating Dose, Group I | 15.9 |
| 10% Reduction of Combination of Esmeron® and Nimbex®, Group S | 16.2 |
| 20% Reduction of Combination of Esmeron® and Nimbex®, Group L | 14.1 |
"Before induction of anesthesia, non invasive blood pressure was measured for baseline.~And after injection of NMBAs, non invasive blood pressure was measured at 10 min." (NCT02495038)
Timeframe: Before and after induction of anesthesia, an average 10 min.
| Intervention | mmHg (Mean) | |
|---|---|---|
| Systolic pressure | Diastolic pressure | |
| 10% Reduction of Combination of Esmeron® and Nimbex®, Group S | 128.3 | 76.7 |
| 20% Reduction of Combination of Esmeron® and Nimbex®, Group L | 128.4 | 74.8 |
| Intubating Dose, Group I | 128.3 | 75.6 |
Total IV hydromorphone administered during surgery to 24 hours post surgery (NCT00913003)
Timeframe: 24 hour
| Intervention | miligrams (Mean) |
|---|---|
| Placebo | 2.33 |
| Lidocaine | 1.5 |
(NCT00913003)
Timeframe: 7 days
| Intervention | Participants (Number) |
|---|---|
| Placebo | 0 |
| Lidocaine | 0 |
Nausea at any time during the post operative period for 48 hours (NCT00913003)
Timeframe: Immediate post operative to 48 hours
| Intervention | Participants (Number) |
|---|---|
| Placebo | 11 |
| Lidocaine | 11 |
Distance (mm) from the left of the 100-mm visual analog scale (reflecting magnitude of pain) recorded at time of IUD Placement. Scale range is from 0mm (no pain) to 100mm (worst pain possible). A lower score (less pain) is considered a better outcome. (NCT02219308)
Timeframe: Moment of IUD insertion
| Intervention | mm (Median) |
|---|---|
| No Paracervical Block (Sham PCB) | 54 |
| Paracervical Block (PCB) | 33 |
Distance (mm) from the left of the 100-mm visual analog scale of pain at various time points. Scale range is 0mm (no pain) to 100mm (worst pain possible). Lower scores are considered better outcomes. (NCT02219308)
Timeframe: Anticipation of procedure through 5 minutes after IUD placement
| Intervention | mm (Median) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Anticipated Pain | Baseline Pain | Speculum Insertion | Capped Needle or PCB | Tenaculum placement | Uterine Sounding | IUD placement | 5 mins after IUD placement | Overall pain | |
| No Paracervical Block (Sham PCB) | 51 | 0 | 6 | 8 | 10 | 47 | 54 | 27 | 51 |
| Paracervical Block (PCB) | 58 | 0 | 10 | 30 | 15 | 30 | 33 | 12 | 30 |
Patients will be asked to fill out questionnaires to provide insight into how their condition is progressing, consisting of components of the American Shoulder and Elbow Surgeons (ASES) total score. The maximum score is 100, made up by pain and function components' sums. Only the total score is recorded, 100 being full normal function without pain, 0 being severe pain and no function. (NCT01123889)
Timeframe: 12 weeks from initial injection of corticosteroid versus platelet rich plasma
| Intervention | units on a scale (Mean) |
|---|---|
| Control | 41.6 |
| Experimental | 86.1 |
Patients will be asked to fill out questionnaires to provide insight into how their condition is progressing, consisting of components of the American Shoulder and Elbow Surgeons (ASES) total score. The maximum score is 100, made up by pain and function components' sums. Only the total score is recorded, 100 being full normal function without pain, 0 being severe pain and no function. (NCT01123889)
Timeframe: 15 minutes prior to initial injection of corticosteroid versus platelet rich plasma
| Intervention | units on a scale (Mean) |
|---|---|
| Control | 35.0 |
| Experimental | 43.9 |
Patients will be asked to fill out questionnaires to provide insight into how their condition is progressing, consisting of components of the American Shoulder and Elbow Surgeons (ASES) total score. The maximum score is 100, made up by pain and function components' sums. Only the total score is recorded, 100 being full normal function without pain, 0 being severe pain and no function. (NCT01123889)
Timeframe: 6 weeks from initial injection of corticosteroid versus platelet rich plasma
| Intervention | units on a scale (Mean) |
|---|---|
| Control | 81.6 |
| Experimental | 70.0 |
Pain as measured by the Visual Analog Scale after first injection. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Baseline - immediately after the injection
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.197 |
| Group 2 (Ketorolac) | 3.577 |
| Group 3 (Kenalog) | 3.677 |
Pain as measured by the Visual Analog Scale prior to first injection. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Baseline - pre-injection
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 5.77 |
| Group 2 (Ketorolac) | 4.57 |
| Group 3 (Kenalog) | 4.67 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Day 2
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 2.347 |
| Group 2 (Ketorolac) | 2.837 |
| Group 3 (Kenalog) | 2.67 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 1
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.397 |
| Group 2 (Ketorolac) | 3.7 |
| Group 3 (Kenalog) | 3.257 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 12
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.447 |
| Group 2 (Ketorolac) | 1.417 |
| Group 3 (Kenalog) | 2.027 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 2
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.547 |
| Group 2 (Ketorolac) | 2.67 |
| Group 3 (Kenalog) | 2.57 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 4
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.547 |
| Group 2 (Ketorolac) | 2.67 |
| Group 3 (Kenalog) | 2.317 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 6
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.357 |
| Group 2 (Ketorolac) | 2.757 |
| Group 3 (Kenalog) | 2.687 |
(NCT02502487)
Timeframe: after withdrawal of cystoscope
| Intervention | times per minute (Mean) |
|---|---|
| Tetracaine Gel Group | 19.7 |
| Dorsal Penile Nerve Block Group | 19.4 |
| Combination Group | 19.4 |
(NCT02502487)
Timeframe: at cystoscopic inspection of external sphincter
| Intervention | times per minute (Mean) |
|---|---|
| Tetracaine Gel Group | 20.1 |
| Dorsal Penile Nerve Block Group | 19.8 |
| Combination Group | 19.8 |
(NCT02502487)
Timeframe: at cystoscopic inspection of penile and bulbar Urthra
| Intervention | times per minute (Mean) |
|---|---|
| Tetracaine Gel Group | 20.0 |
| Dorsal Penile Nerve Block Group | 19.8 |
| Combination Group | 19.6 |
(NCT02502487)
Timeframe: before gel administration
| Intervention | times per minute (Mean) |
|---|---|
| Tetracaine Gel Group | 19.8 |
| Dorsal Penile Nerve Block Group | 19.6 |
| Combination Group | 19.5 |
(NCT02502487)
Timeframe: after withdrawal of cystoscope
| Intervention | Beats per minute (Mean) |
|---|---|
| Tetracaine Gel Group | 76.7 |
| Dorsal Penile Nerve Block Group | 72.3 |
| Combination Group | 71.6 |
(NCT02502487)
Timeframe: at cystoscopic inspection of external sphincter
| Intervention | Beats per minute (Mean) |
|---|---|
| Tetracaine Gel Group | 96.7 |
| Dorsal Penile Nerve Block Group | 90.2 |
| Combination Group | 86.2 |
(NCT02502487)
Timeframe: at cystoscopic inspection of penile and bulbar urethra
| Intervention | Beats per minute (Mean) |
|---|---|
| Tetracaine Gel Group | 84.8 |
| Dorsal Penile Nerve Block Group | 83.8 |
| Combination Group | 81.1 |
(NCT02502487)
Timeframe: before gel administration
| Intervention | Beats per minute (Mean) |
|---|---|
| Tetracaine Gel Group | 75.0 |
| Dorsal Penile Nerve Block Group | 75.9 |
| Combination Group | 73.6 |
(NCT02502487)
Timeframe: after withdrawal of cystoscope
| Intervention | mmHg (Mean) |
|---|---|
| Tetracaine Gel Group | 99.3 |
| Dorsal Penile Nerve Block Group | 95.7 |
| Combination Group | 95.2 |
(NCT02502487)
Timeframe: at cystoscopic inspection of external sphincter
| Intervention | mmHg (Mean) |
|---|---|
| Tetracaine Gel Group | 113.7 |
| Dorsal Penile Nerve Block Group | 105.8 |
| Combination Group | 104.8 |
(NCT02502487)
Timeframe: at cystoscopic inspection of penile and bulbar urthra
| Intervention | mmHg (Mean) |
|---|---|
| Tetracaine Gel Group | 100 |
| Dorsal Penile Nerve Block Group | 99.8 |
| Combination Group | 98.2 |
(NCT02502487)
Timeframe: before gel administration
| Intervention | mmHg (Mean) |
|---|---|
| Tetracaine Gel Group | 95.3 |
| Dorsal Penile Nerve Block Group | 96.6 |
| Combination Group | 95.1 |
(NCT02502487)
Timeframe: after withdrawal of cystoscope
| Intervention | percentage (Median) |
|---|---|
| Tetracaine Gel Group | 99 |
| Dorsal Penile Nerve Block Group | 98 |
| Combination Group | 99 |
(NCT02502487)
Timeframe: at cystoscopic inspection of external sphincter
| Intervention | percentage (Median) |
|---|---|
| Tetracaine Gel Group | 99 |
| Dorsal Penile Nerve Block Group | 98 |
| Combination Group | 99 |
(NCT02502487)
Timeframe: at cystoscopic inspection of penile and bulbar urthra
| Intervention | percentage (Median) |
|---|---|
| Tetracaine Gel Group | 99 |
| Dorsal Penile Nerve Block Group | 98 |
| Combination Group | 99 |
(NCT02502487)
Timeframe: before gel administration
| Intervention | percentage (Median) |
|---|---|
| Tetracaine Gel Group | 99 |
| Dorsal Penile Nerve Block Group | 98 |
| Combination Group | 99 |
A visual analog scale (VAS) ranging from 0 to 10 was used to assess the patients' pain during the procedure. 0 means no pain, 1 to 3 means mild pain, 4 to 7 means moderate pain, and 8 to 10 means severe pain. Patients were asked the VAS score to express the degree of pain at each time point. (NCT02502487)
Timeframe: after withdrawal of cystoscope
| Intervention | units on a scale (Median) |
|---|---|
| Tetracaine Gel Group | 0 |
| Dorsal Penile Nerve Block Group | 0 |
| Combination Group | 0 |
A visual analog scale (VAS) ranging from 0 to 10 was used to assess the patients' pain during the procedure. 0 means no pain, 1 to 3 means mild pain, 4 to 7 means moderate pain, and 8 to 10 means severe pain. Patients were asked the VAS score to express the degree of pain at each time point. (NCT02502487)
Timeframe: at cystoscopic inspection of external sphincter
| Intervention | units on a scale (Median) |
|---|---|
| Tetracaine Gel Group | 6 |
| Dorsal Penile Nerve Block Group | 4 |
| Combination Group | 4 |
A visual analog scale (VAS) ranging from 0 to 10 was used to assess the patients' pain during the procedure. 0 means no pain, 1 to 3 means mild pain, 4 to 7 means moderate pain, and 8 to 10 means severe pain. Patients were asked the VAS score to express the degree of pain at each time point. (NCT02502487)
Timeframe: at cystoscopic inspection of penile and bulbar urethra
| Intervention | units on a scale (Median) |
|---|---|
| Tetracaine Gel Group | 1 |
| Dorsal Penile Nerve Block Group | 1 |
| Combination Group | 1 |
A visual analog scale (VAS) ranging from 0 to 10 was used to assess the patients' pain during the procedure. 0 means no pain, 1 to 3 means mild pain, 4 to 7 means moderate pain, and 8 to 10 means severe pain. Patients were asked the VAS score to express the degree of pain at each time point. (NCT02502487)
Timeframe: at cystoscopic inspection of prostate and bladder
| Intervention | units on a scale (Median) |
|---|---|
| Tetracaine Gel Group | 2 |
| Dorsal Penile Nerve Block Group | 0 |
| Combination Group | 0 |
A visual analog scale (VAS) ranging from 0 to 10 was used to assess the patients' pain during the procedure. 0 means no pain, 1 to 3 means mild pain, 4 to 7 means moderate pain, and 8 to 10 means severe pain. Patients were asked the VAS score to express the degree of pain at each time point. (NCT02502487)
Timeframe: before gel administration
| Intervention | units on a scale (Median) |
|---|---|
| Tetracaine Gel Group | 0 |
| Dorsal Penile Nerve Block Group | 0 |
| Combination Group | 0 |
Within 3 hours from time of culture acquisition, the samples will be vortexed for 30 seconds and 100µl aliquots will be plated onto 5% sheep blood and chocolate agar plates. These plates will be incubated with 5% carbon dioxide at 35˚ C for 72 hours. After 72 hours all plates will be read for colony count and identification of all isolates will be performed using routine microbiological methods. The natural log of bacterial bacterial colony count will be used for the outcome measure. (NCT00827073)
Timeframe: (1) Pre-antibiotics swab, and (2) Post-study medication (pre surgery)
| Intervention | Ln(bacterial colony count) (Mean) |
|---|---|
| Tetracaine 0.5% Drop | -0.14 |
| Lidocaine 2% Jelly | -0.52 |
(NCT00827073)
Timeframe: (1) Pre-antibiotics swab and (2) Post-study medication (pre surgery)
| Intervention | bacterial spceies (Mean) | |
|---|---|---|
| pre number of bacterial spices | post surgery number of bacterial speices | |
| Lidocaine 2% Jelly | 1 | 1 |
| Tetracaine 0.5% Drop | 1 | 1 |
"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes
| Intervention | Intensity score (Mean) |
|---|---|
| Topical KeAmLi Combo | 62.7 |
| Topical Ketamine | 63.1 |
| Topical Amitriptyline | 69.2 |
| Topical Lidocaine | 65.8 |
| Topical Vehicle | 61.9 |
Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes
| Intervention | mN (Mean) | |
|---|---|---|
| Mechanical Detection Threshold | Mechanical Pain Threshold | |
| Topical Amitriptyline | 3.573423965 | 152.4768146 |
| Topical KeAmLi Combo | 3.519376956 | 152.3293608 |
| Topical Ketamine | 3.464204768 | 135.9 |
| Topical Lidocaine | 3.546037659 | 126.9 |
| Topical Vehicle | 3.525692637 | 148.7138273 |
Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes
| Intervention | Degrees celsius (Mean) | |
|---|---|---|
| Warm Detection Threshold | Heat Pain Threshold | |
| Topical Amitriptyline | 33.9 | 40.0 |
| Topical KeAmLi Combo | 33.6 | 39.8 |
| Topical Ketamine | 34.0 | 40.0 |
| Topical Lidocaine | 33.7 | 39.4 |
| Topical Vehicle | 33.8 | 39.7 |
The participants development of chronic persistent pain 3 months after surgery as determined by character severity (yes/no). (NCT01619852)
Timeframe: 3 months
| Intervention | participants (Number) |
|---|---|
| Group L | 2 |
| .9% Normal Saline Placebo | 6 |
The amount of opioid analgesics consumed was converted to an equivalent dose of intravenous morphine. (NCT01619852)
Timeframe: 24 hours
| Intervention | equivalent dose of intravenous morphine (Median) |
|---|---|
| Group L | 34 |
| .9% Normal Saline Placebo | 39 |
Postoperative pain within the first 24 hours. Area under the numeric rating scale for pain versus time curve during the first 24 hours after surgery (score * hr). Numeric rating scale for pain on a scale of 0-10 (0 is no pain and 10 is high pain) versus time curve during the first 24 hours ( score * hr). The pain scores were collected upon arrival to recovery area, 30 minutes, 1 hour and every 6 hours up to 24 hours following the procedure. Minimum score is 60, Maximum score is 170. A higher value indicates more pain. (NCT01619852)
Timeframe: 24 hours
| Intervention | score on a scale (Median) |
|---|---|
| Group L | 116 |
| .9% Normal Saline Placebo | 119 |
Quality of recovery (QoR-40 instrument) is a 40-item questionnaire that provides a global score and sub-scores across five dimensions: patient support, comfort, emotions, physical independence, and pain. Score range: 40 to 200. A score of 40 demonstrates poor recovery and a maximum score of 200 represents good recovery. The higher the score the better recovery after surgery. (NCT01619852)
Timeframe: 24 hours post operative
| Intervention | units on a scale (Median) |
|---|---|
| Lidocaine (Group L) | 158 |
| .9% Normal Saline Placebo | 169 |
The development of chronic pain 3 months after surgery determined by the Leads Assessment of Neuropathic Symptoms and Signs (LANSS) scale, a valid 7-item tool for identifying patients whose pain is dominated by neuropathic mechanisms. Each item is a binary response (yes or no) to the presence of symptoms (5 items) or clinical signs (2 items), range 0-24 points. A score ≥ 12, neuropathic mechanisms are likely to be contributing to the patient's pain. A score < 12 is unlikely to be contributing. McGill questionnaire (Sensory domain) - 11 descriptors rated on an intensity scale as 0=none, 1=mild, 2=moderate, 3=severe. The higher the score, greater the pain (range 0-33). McGill questionnaire (Motivational-affective) 4 affect descriptors rated on an intensity scale as 0=none, 1=mild, 2=moderate, 3=severe.The higher the score the greater the pain (range 0-12) Brief pain inventory - pain severity (0, no pain, 10 excruciating pain); Greater the score; greater the pain (range 0-10). (NCT01619852)
Timeframe: 3 months
| Intervention | units on a scale (Median) | |||
|---|---|---|---|---|
| S-LANNS | McGill Questionaire-Sensory Discrimation | McGill Questionaire-Motivational-affective | Brief Pain Inventory | |
| .9% Normal Saline Placebo | 3 | 3 | 0 | 1 |
| Group L | 3 | 4 | 0 | 1 |
Quality of recovery 40 score at 24 hours after the surgical procedure. 40 being a poor recovery and 200 being a good recovery. (NCT01106846)
Timeframe: 24 hours post operative
| Intervention | units on scale (Mean) |
|---|---|
| Group A: Saline Group | 191.2 |
| Group B: 1% Ketamine Group | 191.1 |
"Muscle strength was measured for forward flexion and abduction of the shoulder per Medical Research Council (MRC) scale in each participants. Their mean +/- SD were calculated in each group.~MRC scale:~Grade 5: Normal and can move against full resistance. Grade 4: Reduced but can move against resistance. Grade 3: Can move only against gravity Grade 2: Can move without gravity Grade 1: Only a trace of movement Grade 0: No movement." (NCT00998868)
Timeframe: within one month after enrollment
| Intervention | Units on a scale (minimum 0, maximum 5) (Mean) |
|---|---|
| Hemiplegia | 1.96 |
All patients underwent ultrasonography (USG) for the both, affected and unaffected, shoulders. USG routinely examined biceps, subscapularis, supraspinatus, and infraspinatus tendons as for the partial or complete tears, calcifications, bony irregularity and bursal swellings. (NCT00998868)
Timeframe: within one month after enrollment
| Intervention | participants (Number) |
|---|---|
| Hemiplegia | 29 |
All patients were performed ultrasonography (USG) for the both, affected and unaffected, shoulders. USG routinely examined biceps, subscapularis, supraspinatus, and infraspinatus tendons as for the partial or complete tears, calcifications, bony irregularity and bursal swellings. (NCT00998868)
Timeframe: within one month after enrollment
| Intervention | participants (Number) |
|---|---|
| Hemiplegia | 18 |
The glenohumeral joint subluxation was examined by palpating the subacromial regions of the both sides and comparing the affected side with the unaffected side while patients are seated and relaxed. If the palpated space between the acromion and the humeral head was wider on the affected side by one half finger breath or more, it was judged to be subluxation. (NCT00998868)
Timeframe: within one month after enrollment
| Intervention | participants (Number) |
|---|---|
| Hemiplegia | 21 |
Pain during activity will be evaluated by visual analog scale (active pain VAS). The active pain visual analog scale change from baseline to 3 months after intervention is the primary outcome. Visual analog scale is scored 0 to 10, higher scored meaning worse outcome. Negative values in change of pain during activity indicate improvement in pain. (NCT02298023)
Timeframe: Baseline and 3 months after intervention
| Intervention | units on a scale (Mean) |
|---|---|
| Mesenchymal Stem Cell Group | -1.4 |
| Active Control (Fibrin Glue) Group | -1.5 |
| Control (Normal Saline )Group | -3.0 |
Functional score of the shoulder was assessed by American Shoulder and Elbow Surgeons shoulder score which is a questionnaire dedicated to the functional evaluation of the shoulder. It is scored from 0 to 100, higher scores meaning better outcome. (NCT02298023)
Timeframe: Baseline, 6 weeks, 12 weeks, 6, 12, 24 months after intervention
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| baseline | week 6 | month 3 | month 6 | month 12 | year 2 | |
| Active Control (Fibrin Glue) Group | 64.7 | 70.6 | 73.7 | 76.7 | 76.0 | 80.0 |
| Control (Normal Saline )Group | 54.7 | 65.9 | 63.6 | 63.9 | 74.4 | 89.3 |
| Mesenchymal Stem Cell Group | 58.9 | 52.4 | 67.9 | 63.4 | 70.6 | 71.6 |
Shoulder function is assessed by DASH score which is questionnaire dedicated to evaluate the function of the upper extremity. It is scored from 0 (no disability) to 100 (most severe disability). (NCT02298023)
Timeframe: Baseline, 6 weeks, 12 weeks, 6, 12, 24 months after intervention
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| baseline | week 6 | month 3 | month 6 | month 12 | year 2 | |
| Active Control (Fibrin Glue) Group | 35.2 | 25.8 | 19.2 | 19.8 | 20.5 | 22.8 |
| Control (Normal Saline )Group | 37.6 | 28.1 | 28.3 | 27.1 | 20.3 | 20.1 |
| Mesenchymal Stem Cell Group | 32.3 | 36.7 | 24.0 | 25.0 | 31.1 | 20.3 |
Pain during activity assessed by visual analog scale (VAS), scored 0 to 10, higher scores meaning worse outcome (NCT02298023)
Timeframe: Baseline, 6 weeks, 12 weeks, 6, 12, 24 months after intervention
| Intervention | units on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| baseline | week 6 | month 3 | month 6 | month 12 | year 2 | |
| Active Control (Fibrin Glue) Group | 4.7 | 3.2 | 3.2 | 2.8 | 3.2 | 3.2 |
| Control (Normal Saline )Group | 6.6 | 4.6 | 3.6 | 4.3 | 3.1 | 1.1 |
| Mesenchymal Stem Cell Group | 5.7 | 6.0 | 4.4 | 4.3 | 3.7 | 4.4 |
Pain during rest assessed by visual analog scale (VAS), scored 0 to 10, higher scores meaning worse outcome. (NCT02298023)
Timeframe: Baseline, 6 weeks, 12 weeks, 6, 12, 24 months after intervention
| Intervention | units on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| baseline | week 6 | month 3 | month 6 | month 12 | year 2 | |
| Active Control (Fibrin Glue) Group | 2.4 | 2.2 | 1.9 | 1.4 | 1.8 | 0.8 |
| Control (Normal Saline )Group | 3.6 | 3.0 | 2.7 | 2.4 | 1.3 | 0.5 |
| Mesenchymal Stem Cell Group | 3.9 | 4.0 | 2.8 | 2.9 | 2.9 | 2.0 |
Shoulder function is assessed by UCLA shoulder score which is a composite of range of motion examination and questionnaire dedicated to evaluate the function of the shoulder. It is scored from 0 to 35, higher scores meaning better shoulder function. (NCT02298023)
Timeframe: Baseline, 6 weeks, 12 weeks, 6, 12, 24 months after intervention
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| baseline | week 6 | month 3 | month 6 | month 12 | year 2 | |
| Active Control (Fibrin Glue) Group | 19.0 | 22.3 | 23.6 | 23.6 | 24.5 | 24.6 |
| Control (Normal Saline )Group | 17.5 | 22.9 | 21.4 | 22.8 | 28.0 | 31.3 |
| Mesenchymal Stem Cell Group | 20.3 | 20.0 | 26.4 | 22.7 | 23.6 | 24.4 |
Self reported pain intensity during activity will be evaluated by visual analogue scale (0 = no pain, 10 = pain as bad as can be), higher scores meaning worse outcome. (NCT01856140)
Timeframe: Baseline, 6 weeks, 12 weeks after intervention
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| Baseline | Post-injection 6 weeks | Post-injection 12 weeks | |
| 1 Million Cells/ml of ALLO-ASC | 3.57 | 2.93 | 1.68 |
| 10 Million Cells/ml of ALLO-ASC | 3.02 | 1.60 | 0.87 |
"Defect areas were measured as the largest defect of the common extensor tendon. Higher value means larger defect area.~With the patient supine position with the elbow in 30' flexion and full pronation, the cephalic end of the ultrasound transducer was placed on the lateral epicondyle and the long axis of the transducer was aligned with the long axis of radius. The alignment of the transducer and radius was achieved by visualizing contours of the bony structures. Multiple cross-sectional images were saved by shifting the transducer medio-laterally by 2mm at a time. Acquiring images were repeated three times.~Among the saved images, one image showing the largest defect were selected for every patients at every time points. Manual measurements of the defect area were conducted by tracking the perimeter using ImageJ 1.48 software (National Institutes of Health, http://imagej.nih.gov/ij/) and were repeated three times by two examiners in random orders and then, averaged." (NCT01856140)
Timeframe: Baseline, 6 weeks, and 12 weeks after the intervention
| Intervention | mm^2 (Mean) | ||
|---|---|---|---|
| Baseline | Post-injection 6weeks | Post-injection 12 weeks | |
| 1 Million Cells/ml of ALLO-ASC | 4197 | 4163 | 2381 |
| 10 Million Cells/ml of ALLO-ASC | 5246 | 4383 | 2516 |
"Defect areas were measured as the largest defect of the common extensor tendon. Higher value means larger defect area.~With the patient supine position with the elbow in 30' flexion and full pronation, the transducer was placed on the proximal forearm just distal to the radial head, aligning the long axis of the transducer perpendicular to the long axis of the forearm. Viewing the round radius at the horizontal center, the transducer was shifted proximally by 2mm and multiple images were saved after the transducer passed the radial head until it slid over the prominence. Acquiring images were repeated three times.~Among the saved images, one image showing the largest defect were selected for every patients at every time points. Manual measurements of the defect area were conducted by tracking the perimeter using ImageJ 1.48 software (National Institutes of Health, http://imagej.nih.gov/ij/) and were repeated three times by two examiners in random orders and then, averaged." (NCT01856140)
Timeframe: Baseline, 6 weeks, and 12 weeks after the intervention
| Intervention | mm^2 (Mean) | ||
|---|---|---|---|
| Baseline | Post-injection 6 weeks | Post-injection 12 weeks | |
| 1 Million Cells/ml of ALLO-ASC | 3726 | 3797 | 2703 |
| 10 Million Cells/ml of ALLO-ASC | 5018 | 2849 | 2223 |
The Modified Mayo clinic performance index for the elbow measures pain, motion, stability, and daily functions. (0 to 100) Higher score means better function. (NCT01856140)
Timeframe: Baseline, 6 weeks, 12 weeks after the intervention
| Intervention | score on a scale (Median) | ||
|---|---|---|---|
| Baseline | Post-injection 6 weeks | Post-injection 12 weeks | |
| 1 Million Cells/ml of ALLO-ASC | 57.92 | 83.75 | 87.92 |
| 10 Million Cells/ml of ALLO-ASC | 70.00 | 90.41 | 91.67 |
Participants in this study underwent TPIs by the following method. The needle was inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. This was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain, one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Post Injections Up to Three Months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketorolac | 1 |
| Lidocaine | 0 |
| Dexamethasone | 0 |
The BPI was evaluated on a scale from 0-10. Zero would mean no interference and 10 would be calculated at complete interferences. We used a 7-point questionnaire about pain. All scores were calculated at baseline and three months. (NCT03028012)
Timeframe: Baseline and Three Months
| Intervention | score on a scale (Number) | |||
|---|---|---|---|---|
| Participant Number #3 at Baseline | Participant Number #3 at 3 Months | Participant Number #8 at Baseline | Participant #8 at 3 Months | |
| Ketorolac | 8 | 3 | 5 | 3 |
TPI were treated with a needle inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. Such was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain,one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Injection and Three Month Post Injection(s)
| Intervention | score on a scale (Number) | |||
|---|---|---|---|---|
| Participant Number 3 at Baseline | Participant Number 3 at 3 Months | Participant Number 8 at Baseline | Participant Number 8 at 3 Months | |
| Ketorolac | 8 | 3 | 5 | 3 |
154 reviews available for lidocaine and Ache
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc | 2016 |
Pharmacology of the Equine Foot: Medical Pain Management for Laminitis.
Topics: Analgesics; Animals; Horse Diseases; Horses; Lidocaine; Pain; Pain Management | 2021 |
Do Computerized Delivery Systems Promote Less Pain and Anxiety Compared to Traditional Local Anesthesia in Dental Procedures? A Systematic Review of the Literature.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Anxiety; Carticaine; Humans; Lidoc | 2022 |
Bacteriostatic preserved saline for pain-free periocular injections: review.
Topics: Anesthetics, Local; Benzyl Alcohol; Botulinum Toxins, Type A; Double-Blind Method; Epinephrine; Huma | 2022 |
Present status and future directions-Mechanisms and management of local anaesthetic failures.
Topics: Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents; Humans; Lidocaine; Mandibular Nerv | 2022 |
Comparative efficacy of anaesthetic methods for closed reduction of paediatric forearm fractures: a systematic review.
Topics: Anesthetics; Child; Forearm; Fractures, Bone; Humans; Lidocaine; Nerve Block; Pain | 2022 |
Factors Associated With Low Procedural Pain Scores Among 1- to 5-Year-Old Patients Undergoing Facial Laceration Repair.
Topics: Anti-Anxiety Agents; Child, Preschool; Epinephrine; Humans; Infant; Lacerations; Lidocaine; Pain; Pa | 2023 |
EFFICACY OF 4% ARTICAINE BUCCAL INFILTRATION VERSUS INFERIOR ALVEOLAR NERVE BLOCK FOR MANDIBULAR MOLARS WITH SYMPTOMATIC IRREVERSIBLE PULPITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS.
Topics: Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Molar; Ner | 2022 |
Patient Comfort with Various Local Infiltration Anesthetics for Minor Oculoplastic Surgery: A Systematic Review and Network Meta-Analysis.
Topics: Anesthesia, Local; Anesthetics, Local; Bicarbonates; Double-Blind Method; Epinephrine; Felypressin; | 2022 |
Intra-articular lidocaine versus intravenous sedation for closed reduction of acute anterior shoulder dislocation in the emergency department: a systematic review and meta-analysis.
Topics: Adolescent; Anesthetics, Local; Emergency Service, Hospital; Humans; Lidocaine; Pain; Shoulder Dislo | 2022 |
The role of corticosteroid injections in treating plantar fasciitis: A systematic review and meta-analysis.
Topics: Adrenal Cortex Hormones; Extracorporeal Shockwave Therapy; Fasciitis, Plantar; Humans; Lidocaine; Pa | 2023 |
Effects of reduction technique for acute anterior shoulder dislocation without sedation or intra-articular pain management: a systematic review and meta-analysis.
Topics: Humans; Injections, Intra-Articular; Lidocaine; Pain; Shoulder Dislocation | 2023 |
Physiology of pregnancy and oral local anesthesia considerations.
Topics: Anesthesia, Local; Anesthetics, Local; Epinephrine; Female; Humans; Lidocaine; Pain; Pregnancy | 2023 |
Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants.
Topics: Analgesics; Anesthetics, Local; Apnea; Bradycardia; Fentanyl; Humans; Hypnotics and Sedatives; Infan | 2023 |
Acupuncture for lumbar myofascial pain syndrome: systematic review and Meta-analysis.
Topics: Acupuncture Therapy; Anti-Inflammatory Agents, Non-Steroidal; Humans; Lidocaine; Myofascial Pain Syn | 2023 |
Efficacy of Topical Anesthetics in Pain Perception During Mini-implant Insertion: Systematic Review of Controlled Clinical Trials.
Topics: Anesthetics, Local; Humans; Lidocaine; Pain; Pain Measurement; Pain Perception; Randomized Controlle | 2019 |
Topical anesthetics for pediatric laser treatment.
Topics: Anesthetics, Local; Drug Combinations; Drug Therapy, Combination; Humans; Lidocaine; Low-Level Light | 2019 |
Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta-analysis.
Topics: Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Local; Humans; Lidocaine; Network Meta-Analysis; | 2019 |
BET 2: Does topical lidocaine improve oral intake in children with painful mouth ulcers?
Topics: Administration, Topical; Feeding Behavior; Humans; Lidocaine; Oral Ulcer; Pain; Pain Management | 2020 |
The efficacy of Antipyretic Analgesics administration intravenously for Preventing Rocuronium-Associated Pain/Withdrawal Response: a systematic review and meta-analysis.
Topics: Administration, Intravenous; Analgesics; Anesthetics, Local; Antipyretics; Humans; Lidocaine; Neurom | 2020 |
Efficacy of Eutectic Mixture of Local Anesthetics on Pain Control During Extracorporeal Shock Wave Lithotripsy: A Systematic Review and Meta-Analysis.
Topics: Analgesia; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Humans; | 2020 |
Severe Postmenopausal Genital Pain Treated Successfully With Prolonged Estrogen Therapy: A Case Series and Narrative Review.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Drug Therapy, Combination; Estradiol; Estrogens; Female | 2020 |
Onset, Duration, and Pain Score Obtained Using Lidocaine Mixed With Epinephrine and Bicarbonate in Plastic Surgery.
Topics: Anesthesia, Local; Anesthetics, Local; Drug Combinations; Epinephrine; Humans; Lidocaine; Pain; Pain | 2020 |
Management of pain in newborn circumcision: a systematic review.
Topics: Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, Prilocaine Dr | 2021 |
Topics: Cystoscopy; Humans; Lidocaine; Pain; Pain Measurement; Plastic Surgery Procedures | 2020 |
Quaternary Lidocaine Derivatives: Past, Present, and Future.
Topics: Anesthetics, Local; Animals; Humans; Lidocaine; Pain; Pain Management | 2021 |
Ropivacaine versus lidocaine infiltration for postpartum perineal pain: A systematic review and meta-analysis.
Topics: Adult; Anesthesia, Local; Female; Humans; Lidocaine; Pain; Pain Management; Pain Measurement; Perine | 2021 |
Pharmacological control of pain during propofol injection: a systematic review and meta-analysis.
Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Humans; Injections; Lidocaine; Pain; Propofol; | 2021 |
Onset Mechanism and Pharmaceutical Management of Dry Skin.
Topics: Age Factors; Animals; Deficiency Diseases; Dermatologic Agents; Dietary Supplements; Eczema; Female; | 2021 |
Does the use of topical anesthetics reduce the perception of pain during needle puncture and anesthetic infiltration? Systematic review and meta-analysis of randomized controlled trials.
Topics: Anesthetics, Local; Humans; Lidocaine; Pain; Pain Measurement; Perception; Punctures; Randomized Con | 2022 |
Reduced pain when injecting lidocaine.
Topics: Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Hot Temperature; Humans; Injections, S | 2017 |
Uses and Doses of Local Anesthetics in Fish, Amphibians, and Reptiles.
Topics: Amphibians; Analgesics; Anesthetics, Local; Animal Welfare; Animals; Fishes; Guidelines as Topic; Li | 2017 |
The application of lidocaine to alleviate the discomfort of nasogastric tube insertion: A systematic review and meta-analysis.
Topics: Anesthetics, Local; Humans; Intubation, Gastrointestinal; Lidocaine; Pain; Randomized Controlled Tri | 2018 |
Effectiveness and Safety of Hyaluronic Acid Gel with Lidocaine for the Treatment of Nasolabial Folds: A Systematic Review and Meta-analysis.
Topics: Anesthetics, Local; Dermal Fillers; Drug Combinations; Gels; Humans; Hyaluronic Acid; Lidocaine; Nas | 2018 |
Uterine or paracervical lidocaine application for pain control during intrauterine contraceptive device insertion: a meta-analysis of randomised controlled trials.
Topics: Anesthetics, Local; Female; Humans; Intrauterine Devices; Lidocaine; Pain; Pain Measurement; Randomi | 2018 |
The Effect of 5-Hydroxytryptamine Receptor Antagonist in Preventing Pain/Limb Shrinkage Reaction Associated with Rocuronium Injection.
Topics: Androstanols; Humans; Lidocaine; Pain; Receptors, Serotonin; Rocuronium; Serotonin Antagonists; Sero | 2018 |
Latest Advances in Wide Awake Hand Surgery.
Topics: Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Local; Cost Savings; Developing Coun | 2019 |
Novel Approaches for Treating Pain in Children.
Topics: Administration, Intranasal; Analgesics; Anesthetics, Local; Cannabinoids; Child; Humans; Lidocaine; | 2019 |
Medications for pain relief in outpatient endometrial sampling or biopsy: a systematic review and network meta-analysis.
Topics: Ambulatory Care; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; En | 2019 |
Interventions for the prevention of pain associated with the placement of intrauterine contraceptives: An updated review.
Topics: Administration, Oral; Analgesics; Anesthesia, Local; Female; Humans; Intrauterine Devices; Lidocaine | 2019 |
Towards evidence-based emergency medicine: Best BETs from the Manchester Royal Infirmary. BET 1: Local anaesthetics in intraosseous access.
Topics: Anesthetics, Local; Evidence-Based Emergency Medicine; Humans; Infusions, Intraosseous; Lidocaine; P | 2013 |
Analgesia for infants' circumcision.
Topics: Administration, Cutaneous; Analgesia; Anesthetics, Local; Circumcision, Male; Humans; Infant; Lidoca | 2013 |
Minimizing the pain of local anesthesia injection.
Topics: Anesthesia, Local; Anesthetics, Local; Epinephrine; Humans; Injections, Subcutaneous; Lidocaine; Nee | 2013 |
Minimizing the pain of local anesthesia injection.
Topics: Anesthesia, Local; Anesthetics, Local; Epinephrine; Humans; Injections, Subcutaneous; Lidocaine; Nee | 2013 |
Minimizing the pain of local anesthesia injection.
Topics: Anesthesia, Local; Anesthetics, Local; Epinephrine; Humans; Injections, Subcutaneous; Lidocaine; Nee | 2013 |
Minimizing the pain of local anesthesia injection.
Topics: Anesthesia, Local; Anesthetics, Local; Epinephrine; Humans; Injections, Subcutaneous; Lidocaine; Nee | 2013 |
WITHDRAWN: EMLA and Amethocaine for reduction of children's pain associated with needle insertion.
Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Humans; Infant; Lidocaine; Lidocaine, Prilo | 2014 |
Analgesic options for placement of an intrauterine contraceptive: a meta-analysis.
Topics: Analgesia; Anesthetics, Local; Female; Humans; Intrauterine Devices; Lidocaine; Misoprostol; Oxytoci | 2014 |
Intradermal lidocaine or bacteriostatic normal saline to decrease pain before intravenous catheter insertion: a meta-analysis.
Topics: Catheterization, Peripheral; Humans; Injections, Intradermal; Lidocaine; Pain; Sodium Chloride | 2014 |
Intravenous lidocaine for the treatment of background or procedural burn pain.
Topics: Analgesia; Anesthetics, Intravenous; Anesthetics, Local; Burns; Humans; Lidocaine; Pain; Pain Manage | 2014 |
WITHDRAWN: Adjusting the pH of lidocaine for reducing pain on injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Buffers; Child; Humans; Hydrogen-Ion Concentrat | 2015 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; | 2015 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; | 2015 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; | 2015 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; | 2015 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; | 2015 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; | 2015 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; | 2015 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; | 2015 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; | 2015 |
Intravenous Lidocaine as an Adjuvant for Pain Associated with Sickle Cell Disease.
Topics: Analgesics; Anemia, Sickle Cell; Drug Therapy, Combination; Humans; Infusions, Intravenous; Lidocain | 2015 |
Pharmacological and non-pharmacological interventions for reducing rocuronium bromide induced pain on injection in children and adults.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Androstanols; Anesthetics, Local; Child; Fentanyl; Humans; | 2016 |
Lidocaine for reducing propofol-induced pain on induction of anaesthesia in adults.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia; Anesthesiology; Anesthetics, Intravenous; An | 2016 |
Lidocaine Infusions and Other Options for Opioid-Resistant Pain Due to Pediatric Advanced Cancer.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Resistance; Female; Humans; Infant; Li | 2016 |
Complications from Nasolabial Fold Injection of Calcium Hydroxylapatite for Facial Soft-Tissue Augmentation: A Systematic Review and Meta-Analysis.
Topics: Anesthetics, Local; Biocompatible Materials; Cosmetic Techniques; Durapatite; Humans; Injections; Li | 2016 |
Efficacy and safety of bupivacaine versus lidocaine in local anesthesia of the nasopharynx: A meta-analysis.
Topics: Anesthesia, Local; Bupivacaine; Endoscopy; Humans; Lidocaine; Nasal Surgical Procedures; Nasopharynx | 2016 |
Analgesia in the surgical intensive care unit.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; C | 2017 |
Breastfeeding for procedural pain in infants beyond the neonatal period.
Topics: Anesthetics, Local; Breast Feeding; Crying; Female; Glucose; Heart Rate; Humans; Infant; Infant Care | 2016 |
Breastfeeding for procedural pain in infants beyond the neonatal period.
Topics: Anesthetics, Local; Breast Feeding; Crying; Female; Glucose; Heart Rate; Humans; Infant; Infant Care | 2016 |
Breastfeeding for procedural pain in infants beyond the neonatal period.
Topics: Anesthetics, Local; Breast Feeding; Crying; Female; Glucose; Heart Rate; Humans; Infant; Infant Care | 2016 |
Breastfeeding for procedural pain in infants beyond the neonatal period.
Topics: Anesthetics, Local; Breast Feeding; Crying; Female; Glucose; Heart Rate; Humans; Infant; Infant Care | 2016 |
Efficacy of lidocaine on preventing incidence and severity of pain associated with propofol using in pediatric patients: A PRISMA-compliant meta-analysis of randomized controlled trials.
Topics: Adolescent; Alfentanil; Anesthetics, Intravenous; Anesthetics, Local; Child; Double-Blind Method; Hu | 2017 |
Topical anesthetic creams.
Topics: Administration, Topical; Anesthetics, Local; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combinati | 2008 |
Practical management strategies for the chronic pain patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chro | 2007 |
Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief?
Topics: Anesthetics, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Pain; Pain Measu | 2009 |
Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief?
Topics: Anesthetics, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Pain; Pain Measu | 2009 |
Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief?
Topics: Anesthetics, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Pain; Pain Measu | 2009 |
Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief?
Topics: Anesthetics, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Pain; Pain Measu | 2009 |
Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief?
Topics: Anesthetics, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Pain; Pain Measu | 2009 |
Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief?
Topics: Anesthetics, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Pain; Pain Measu | 2009 |
Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief?
Topics: Anesthetics, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Pain; Pain Measu | 2009 |
Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief?
Topics: Anesthetics, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Pain; Pain Measu | 2009 |
Meta-analysis: does lidocaine gel before flexible cystoscopy provide pain relief?
Topics: Anesthetics, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Pain; Pain Measu | 2009 |
Pain and palliative care pharmacotherapy literature summaries and analyses.
Topics: Alzheimer Disease; Amphetamines; Anesthetics, Local; Anticoagulants; Antidepressive Agents; Depressi | 2009 |
Transient neurologic symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics.
Topics: Anesthesia, Spinal; Anesthetics, Local; Humans; Leg; Lidocaine; Pain; Peripheral Nervous System Dise | 2009 |
Cyclobenzaprine for the treatment of myofascial pain in adults.
Topics: Adult; Amitriptyline; Anesthetics, Local; Clonazepam; Fascia; Humans; Lidocaine; Muscle Relaxants, C | 2009 |
Intravenous infusion tests have limited utility for selecting long-term drug therapy in patients with chronic pain: a systematic review.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Chr | 2009 |
Use of intra-articular lidocaine as analgesia in anterior shoulder dislocation: a review and meta-analysis of the literature.
Topics: Analgesia; Anesthetics, Local; Humans; Injections, Intralesional; Lidocaine; Pain; Shoulder Dislocat | 2009 |
Calcium hydroxylapatite (Radiesse): safety, techniques and pain reduction.
Topics: Anesthetics, Local; Biocompatible Materials; Cosmetic Techniques; Durapatite; Humans; Injections; Li | 2009 |
The efficacy and safety of articaine versus lignocaine in dental treatments: a meta-analysis.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Humans; Injections; Lidocaine | 2010 |
Topical agents or dressings for pain in venous leg ulcers.
Topics: Administration, Topical; Analgesics, Non-Narcotic; Anesthetics, Local; Bandages; Debridement; Humans | 2010 |
Reducing the pain of nasogastric tube intubation with nebulized and atomized lidocaine: a systematic review and meta-analysis.
Topics: Anesthetics, Local; Humans; Intubation, Gastrointestinal; Lidocaine; Pain; Randomized Controlled Tri | 2010 |
Is it all central sensitization? Role of peripheral tissue nociception in chronic musculoskeletal pain.
Topics: Anesthetics, Local; Exercise Therapy; Fibromyalgia; Humans; Hyperalgesia; Lidocaine; Muscle, Skeleta | 2010 |
Local anesthetics as pain therapy in horses.
Topics: Anesthesia, Intravenous; Anesthetics, Local; Animals; Calcium Channels; Horse Diseases; Horses; Infu | 2010 |
Adjusting the pH of lidocaine for reducing pain on injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Buffers; Child; Humans; Hydrogen-Ion Concentrat | 2010 |
Adjusting the pH of lidocaine for reducing pain on injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Buffers; Child; Humans; Hydrogen-Ion Concentrat | 2010 |
Adjusting the pH of lidocaine for reducing pain on injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Buffers; Child; Humans; Hydrogen-Ion Concentrat | 2010 |
Adjusting the pH of lidocaine for reducing pain on injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Buffers; Child; Humans; Hydrogen-Ion Concentrat | 2010 |
Adjusting the pH of lidocaine for reducing pain on injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Buffers; Child; Humans; Hydrogen-Ion Concentrat | 2010 |
Adjusting the pH of lidocaine for reducing pain on injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Buffers; Child; Humans; Hydrogen-Ion Concentrat | 2010 |
Adjusting the pH of lidocaine for reducing pain on injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Buffers; Child; Humans; Hydrogen-Ion Concentrat | 2010 |
Adjusting the pH of lidocaine for reducing pain on injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Buffers; Child; Humans; Hydrogen-Ion Concentrat | 2010 |
Adjusting the pH of lidocaine for reducing pain on injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Buffers; Child; Humans; Hydrogen-Ion Concentrat | 2010 |
Clinical inquiries. What's the best way to control circumcision pain in newborns?
Topics: Anesthetics, Local; Circumcision, Male; Equipment and Supplies; Evidence-Based Medicine; Humans; Inf | 2011 |
Articaine: a review of the literature.
Topics: Age Factors; Anesthesia, Dental; Anesthetics, Local; Carticaine; Humans; Lidocaine; Pain; Safety; Tr | 2011 |
Management of chronic noncancer pain in depressed patients.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2011 |
Analgesia for amniocentesis or chorionic villus sampling.
Topics: Amniocentesis; Analgesia; Anesthesia, Local; Chorionic Villi Sampling; Cryoanesthesia; Female; Human | 2011 |
Topical anesthetics for dermatologic procedures: a review.
Topics: Anesthesia, Local; Anesthetics, Local; Body Surface Area; Cosmetic Techniques; Dermatologic Surgical | 2012 |
Topical anesthetics for dermatologic procedures: a review.
Topics: Anesthesia, Local; Anesthetics, Local; Body Surface Area; Cosmetic Techniques; Dermatologic Surgical | 2012 |
Topical anesthetics for dermatologic procedures: a review.
Topics: Anesthesia, Local; Anesthetics, Local; Body Surface Area; Cosmetic Techniques; Dermatologic Surgical | 2012 |
Topical anesthetics for dermatologic procedures: a review.
Topics: Anesthesia, Local; Anesthetics, Local; Body Surface Area; Cosmetic Techniques; Dermatologic Surgical | 2012 |
Intravenous lidocaine for the treatment of background or procedural burn pain.
Topics: Analgesia; Anesthetics, Intravenous; Anesthetics, Local; Burns; Humans; Lidocaine; Pain; Pain Manage | 2012 |
Topical agents or dressings for pain in venous leg ulcers.
Topics: Administration, Topical; Analgesics; Anesthetics, Local; Bandages; Debridement; Humans; Ibuprofen; L | 2012 |
Topical agents or dressings for pain in venous leg ulcers.
Topics: Administration, Topical; Analgesics; Anesthetics, Local; Bandages; Debridement; Humans; Ibuprofen; L | 2012 |
Topical agents or dressings for pain in venous leg ulcers.
Topics: Administration, Topical; Analgesics; Anesthetics, Local; Bandages; Debridement; Humans; Ibuprofen; L | 2012 |
Topical agents or dressings for pain in venous leg ulcers.
Topics: Administration, Topical; Analgesics; Anesthetics, Local; Bandages; Debridement; Humans; Ibuprofen; L | 2012 |
Principles of office anesthesia: part I. Infiltrative anesthesia.
Topics: Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Contraindication | 2002 |
Effects of indomethacin suppository and lidocaine pomade for the relief of post-episiotomy pain.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Episiotomy; Female; Humans; Indomethaci | 2002 |
Vulvar biopsy. Techniques for reducing patient discomfort.
Topics: Anesthetics, Local; Biopsy; Female; Hemostatic Techniques; Humans; Lidocaine; Lidocaine, Prilocaine | 2001 |
Management strategies for the treatment of neuropathic pain in the elderly.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Anticonvulsants; Antidepressive Agents; Capsaicin; Cog | 2002 |
Topical agents or dressings for pain in venous leg ulcers.
Topics: Administration, Topical; Anesthetics, Local; Bandages; Debridement; Humans; Leg Ulcer; Lidocaine; Li | 2003 |
Pain management in nursing procedures on premature babies.
Topics: Anesthetics, Local; Humans; Infant, Newborn; Infant, Premature; Lidocaine; Lidocaine, Prilocaine Dru | 2003 |
Topical local anesthetics.
Topics: Administration, Cutaneous; Adult; Anesthetics, Combined; Anesthetics, Local; Child; Humans; Lidocain | 2003 |
Transient neurologic symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics.
Topics: Anesthesia, Spinal; Anesthetics, Local; Humans; Leg; Lidocaine; Pain; Randomized Controlled Trials a | 2003 |
A pictorial and video guide to circumcision without pain.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anesthesia; Anesthetics, Local; Attitude of Heal | 2003 |
LOCAL ANESTHETICS.
Topics: Analgesia; Anesthetics; Anesthetics, Local; Arrhythmias, Cardiac; Benzoates; Cough; Ethers; Ketones; | 1963 |
Lidocaine patch 5%.
Topics: Administration, Cutaneous; Anesthetics, Local; Diabetic Neuropathies; Drug Administration Schedule; | 2003 |
Nonopioid and adjuvant analgesics in chronic pain management: strategies for effective use.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal | 2003 |
The use of EMLA cream to decrease venipuncture pain in children.
Topics: Anesthetics, Local; Child; Child Welfare; Controlled Clinical Trials as Topic; Humans; Iontophoresis | 2004 |
The use of EMLA cream to decrease venipuncture pain in children.
Topics: Anesthetics, Local; Child; Child Welfare; Controlled Clinical Trials as Topic; Humans; Iontophoresis | 2004 |
The use of EMLA cream to decrease venipuncture pain in children.
Topics: Anesthetics, Local; Child; Child Welfare; Controlled Clinical Trials as Topic; Humans; Iontophoresis | 2004 |
The use of EMLA cream to decrease venipuncture pain in children.
Topics: Anesthetics, Local; Child; Child Welfare; Controlled Clinical Trials as Topic; Humans; Iontophoresis | 2004 |
The use of EMLA cream to decrease venipuncture pain in children.
Topics: Anesthetics, Local; Child; Child Welfare; Controlled Clinical Trials as Topic; Humans; Iontophoresis | 2004 |
The use of EMLA cream to decrease venipuncture pain in children.
Topics: Anesthetics, Local; Child; Child Welfare; Controlled Clinical Trials as Topic; Humans; Iontophoresis | 2004 |
The use of EMLA cream to decrease venipuncture pain in children.
Topics: Anesthetics, Local; Child; Child Welfare; Controlled Clinical Trials as Topic; Humans; Iontophoresis | 2004 |
The use of EMLA cream to decrease venipuncture pain in children.
Topics: Anesthetics, Local; Child; Child Welfare; Controlled Clinical Trials as Topic; Humans; Iontophoresis | 2004 |
The use of EMLA cream to decrease venipuncture pain in children.
Topics: Anesthetics, Local; Child; Child Welfare; Controlled Clinical Trials as Topic; Humans; Iontophoresis | 2004 |
ELA-max: A new topical lidocaine formulation.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Humans; Lid | 2004 |
[Recognition and treatment of neuropathic pain].
Topics: Analgesics, Opioid; Chronic Disease; Depressive Disorder; Drug Therapy, Combination; Epilepsy; Femal | 2004 |
Patching pain with lidocaine: new uses for the lidocaine 5% patch.
Topics: Administration, Cutaneous; Anesthetics, Local; Back Pain; Humans; Lidocaine; Neuralgia; Osteoarthrit | 2004 |
Pain relief for neonatal circumcision.
Topics: Analgesics; Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, P | 2004 |
Pain relief for neonatal circumcision.
Topics: Analgesics; Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, P | 2004 |
Pain relief for neonatal circumcision.
Topics: Analgesics; Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, P | 2004 |
Pain relief for neonatal circumcision.
Topics: Analgesics; Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, P | 2004 |
Pain relief for neonatal circumcision.
Topics: Analgesics; Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, P | 2004 |
Pain relief for neonatal circumcision.
Topics: Analgesics; Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, P | 2004 |
Pain relief for neonatal circumcision.
Topics: Analgesics; Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, P | 2004 |
Pain relief for neonatal circumcision.
Topics: Analgesics; Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, P | 2004 |
Pain relief for neonatal circumcision.
Topics: Analgesics; Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, P | 2004 |
[Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides].
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Emulsions; Female; Humans; Incidence; Lidocaine; Male; | 2004 |
Local approaches to the pain of pressure ulcers.
Topics: Administration, Cutaneous; Amitriptyline; Anesthetics, Local; Bandages; Humans; Lidocaine; Lidocaine | 2005 |
The vulvodynia guideline.
Topics: Administration, Oral; Administration, Topical; Algorithms; Anticonvulsants; Antidepressive Agents; F | 2005 |
Transient neurologic symptoms after spinal anesthesia with lidocaine versus other local anesthetics: a systematic review of randomized, controlled trials.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Humans; Lidocaine; Nervous System Diseases; Pain; Pat | 2005 |
Use of a eutectic mixture of lidocaine 2.5% and prilocaine 2.5% as a local anesthetic in animals.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Animals; Drug Combinations; Drug | 2005 |
Topical anesthetics for dermal instrumentation: a systematic review of randomized, controlled trials.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy, N | 2005 |
Transient neurologic symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics.
Topics: Anesthesia, Spinal; Anesthetics, Local; Humans; Leg; Lidocaine; Pain; Peripheral Nervous System Dise | 2005 |
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Systemic administration of local anesthetics to relieve neuropathic pain: a systematic review and meta-analysis.
Topics: Anesthetics, Local; Humans; Lidocaine; Mexiletine; Pain; Peripheral Nervous System Diseases; Randomi | 2005 |
Lidocaine iontophoresis for dermal procedure analgesia.
Topics: Adolescent; Adult; Age Factors; Analgesia; Anesthetics, Local; Catheterization, Central Venous; Chil | 2006 |
Pharmacological concept for topical synergistic analgesia of peripheral neuromuscular pain.
Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-St | 2006 |
The role of sodium channels in chronic inflammatory and neuropathic pain.
Topics: Anesthetics, Local; Calcium Signaling; Chronic Disease; Humans; Inflammation; Lidocaine; Nervous Sys | 2006 |
Effects of intraurethral injection of anaesthetic gel for transurethral instrumentation.
Topics: Anesthetics, Local; Cystoscopy; Gels; Humans; Injections; Lidocaine; Male; Pain; Treatment Outcome; | 2006 |
Local anesthesia in transrectal prostate biopsy.
Topics: Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Pain; Prostate; Rect | 2006 |
EMLA and amethocaine for reduction of children's pain associated with needle insertion.
Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Humans; Infant; Lidocaine; Lidocaine, Prilo | 2006 |
Tolerance of local anesthetic for transrectal ultrasound-guided prostate biopsy: our experience and a literature review.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Biop | 2006 |
Use of local anesthesia for arterial punctures.
Topics: Anesthetics, Local; Arteries; Humans; Lidocaine; Pain; Practice Guidelines as Topic; Punctures | 2006 |
Intravenous lidocaine for neuropathic pain: diagnostic utility and therapeutic efficacy.
Topics: Anesthetics, Local; Humans; Infusions, Intravenous; Lidocaine; Mexiletine; Pain; Peripheral Nervous | 2007 |
Adjuvant analgesics for the treatment of neuropathic pain: evaluating efficacy and safety profiles.
Topics: Administration, Cutaneous; Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents; Arthritis; | 2007 |
Intravenous lidocaine: an outdated or underutilized treatment for pain?
Topics: Administration, Intravesical; Humans; Lidocaine; Pain; Respiration, Artificial; United Kingdom | 2007 |
Target pain with topical peripheral analgesics.
Topics: Administration, Topical; Aged; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroid | 2007 |
Lidocaine for pain relief in burn injured patients.
Topics: Analgesia; Anesthetics, Local; Burns; Humans; Injections, Intravenous; Lidocaine; Pain; Randomized C | 2007 |
[Differences in pain anesthetic effect expression on using lidocaine tape for hemodialysis patients].
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Biomedical Research; Humans; Lidocaine; Need | 2007 |
Use of topical lidocaine for cosmetic dermatologic procedures.
Topics: Administration, Cutaneous; Anesthetics, Local; Biocompatible Materials; Cosmetic Techniques; Humans; | 2007 |
Medical treatment of tinnitus.
Topics: Amitriptyline; Anti-Arrhythmia Agents; Auditory Pathways; Drug Combinations; Humans; Lidocaine; Pain | 1984 |
Assessing patient comfort: local infiltration of lidocaine during femoral sheath removal.
Topics: Catheterization; Femoral Artery; Femoral Vein; Humans; Lidocaine; Pain; Pain Measurement; Premedicat | 1995 |
Recent advances in acute pain management.
Topics: Acute Disease; Administration, Oral; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; | 1995 |
Eutectic lidocaine/prilocaine cream. A review of the topical anaesthetic/analgesic efficacy of a eutectic mixture of local anaesthetics (EMLA).
Topics: Anesthetics, Local; Animals; Drug Combinations; Drug Evaluation; Drug Tolerance; Humans; Lidocaine; | 1993 |
Choosing a local anesthetic.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Anxiety; Child; Humans; Injections, Intradermal; Lidoc | 1994 |
Lidocaine overdose: another preventable case?
Topics: Acute Disease; Administration, Topical; Drug Overdose; Humans; Infant; Infant, Newborn; Lidocaine; M | 1994 |
Age-related response to lidocaine-prilocaine (EMLA) emulsion and effect of music distraction on the pain of intravenous cannulation.
Topics: Adolescent; Age Factors; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; D | 1994 |
Causes of neuropathic pain.
Topics: Animals; Blood Glucose; Diabetic Neuropathies; Humans; Leg; Lidocaine; Mexiletine; Pain; Regional Bl | 1993 |
Topical anesthesia and pain management before venipuncture.
Topics: Administration, Cutaneous; Adolescent; Anesthesia, Local; Anesthetics, Local; Bloodletting; Child; C | 1993 |
Use of the eutectic mixture of local anesthetics in young children for procedure-related pain.
Topics: Anesthetics, Local; Child; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Humans; In | 1993 |
Management of painful procedures in the newborn.
Topics: Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Drug Combinations; Hum | 1996 |
Topical anesthetic agents in dermatologic surgery. A review.
Topics: Administration, Cutaneous; Adult; Anesthesia, Local; Anesthetics, Local; Child; Dermatologic Surgica | 1997 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates.
Topics: Acute Disease; Analgesia; Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Humans; Infan | 1998 |
Pain on injection of propofol.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Chemistry, Pharmaceutical; Humans; Injections, Intrave | 1998 |
Topical anesthesia.
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Child; Cocaine; Drug Combinations; Epinephrine; Hu | 1998 |
[Pharma clinics. How I treat...or preventing pain with "patches"].
Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Local; Fentanyl; Lidocaine; Lidocaine, P | 1998 |
Use of topical lidocaine in pediatric laceration repair: a review of topical anesthetics.
Topics: Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Emergency Servi | 1998 |
Reducing the pain of venipuncture.
Topics: Anesthetics, Local; Ethyl Chloride; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain; | 1999 |
Pain management in neonates.
Topics: Anesthesia, Conduction; Anesthetics, Local; Humans; Infant, Newborn; Infant, Premature; Lidocaine; L | 1999 |
Prevention of pain on injection with propofol: a quantitative systematic review.
Topics: Adult; Analgesics, Opioid; Humans; Injections; Lidocaine; Pain; Propofol; Randomized Controlled Tria | 2000 |
Getting the 'ouch' out. Topical anesthesia for procedural pain in children.
Topics: Administration, Topical; Anesthetics, Local; Child; Humans; Lidocaine; Lidocaine, Prilocaine Drug Co | 1999 |
Topical agents or dressings for pain in venous leg ulcers.
Topics: Administration, Topical; Anesthetics, Local; Bandages; Humans; Leg Ulcer; Lidocaine; Lidocaine, Pril | 2000 |
Spinal and supraspinal mechanisms of neuropathic pain.
Topics: Animals; Dizocilpine Maleate; Dynorphins; Humans; Hyperalgesia; Lidocaine; Morphine; Pain; Spinal Co | 2000 |
Potential neurotoxicity of spinal anesthesia with lidocaine.
Topics: Adverse Drug Reaction Reporting Systems; Anesthesia, Spinal; Anesthetics, Local; Animals; Bupivacain | 2000 |
[New anesthetics].
Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Epinephrine; Humans; Lidocaine; Pain; Safety; Ti | 2000 |
[Analgesia for infants. A review of randomized trials].
Topics: Administration, Oral; Analgesia; Anesthetics, Combined; Anesthetics, Local; Databases, Bibliographic | 2000 |
Pain management for neonatal circumcision.
Topics: Acetaminophen; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Circumcision, Male; Hum | 2001 |
Contemporary drug therapy in palliative care: new directions.
Topics: Adrenal Cortex Hormones; Analgesics; Anorexia; Antiemetics; Antitussive Agents; Cachexia; Cough; Dru | 2001 |
Lidocaine-prilocaine cream versus tetracaine gel for procedural pain in children.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Gels; Humans; Infa | 2002 |
Discharge of noradrenergic locus coeruleus neurons in behaving rats and monkeys suggests a role in vigilance.
Topics: Afferent Pathways; Animals; Arousal; Attention; Behavior, Animal; Efferent Pathways; Frontal Lobe; g | 1991 |
[Lidocaine-prilocaine ointment; a welcome addition in local anesthesia].
Topics: Absorption; Anesthesia, Local; Child; Condylomata Acuminata; Drug Combinations; Female; Humans; Lido | 1991 |
Severe lidocaine intoxication by cutaneous absorption.
Topics: Female; Humans; Lidocaine; Lymphoma, T-Cell, Cutaneous; Middle Aged; Ointments; Pain; Skin Absorptio | 1990 |
[Intensive medicine. Myocardial infarct].
Topics: Arrhythmias, Cardiac; Coronary Care Units; Diagnosis, Differential; Digitalis Glycosides; Fibrinolyt | 1972 |
1254 trials available for lidocaine and Ache
| Article | Year |
|---|---|
Effect of precooling injection site and cold anesthetic administration on injection pain, onset, and anesthetic efficacy in maxillary molars with symptomatic irreversible pulpitis: a randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Mo | 2022 |
An Evaluation of High Preprocedural Anxiety and Venipuncture Pain Experienced by Young Children.
Topics: Anesthetics, Local; Anxiety; Child; Child, Preschool; Humans; Lidocaine; Male; Pain; Pain Measuremen | 2021 |
Effect of tourniquet in minor hand surgery on perioperative pain and short-term clinical outcomes: a randomized controlled trial.
Topics: Hand; Humans; Lidocaine; Pain; Pain, Postoperative; Tourniquets | 2022 |
The effect of splash block on the need for analgesia in dogs subjected to video-assisted ovariectomy.
Topics: Analgesia; Anesthetics, Local; Animals; Dogs; Female; Lidocaine; Ovariectomy; Pain | 2022 |
Comparative effectiveness of lidocaine sprays between sitting and supine position for patients undergoing upper gastrointestinal endoscopy: a prospective randomized controlled trial.
Topics: Anesthetics, Local; Endoscopy, Gastrointestinal; Humans; Lidocaine; Pain; Prospective Studies; Sitti | 2022 |
Efficacy of Pre-Treatment with Remimazolam on Prevention of Propofol-Induced Injection Pain in Patients Undergoing Abortion or Curettage: A Prospective, Double-Blinded, Randomized and Placebo-Controlled Clinical Trial.
Topics: Abortion, Induced; Adult; Anesthetics, Intravenous; Benzodiazepines; Dilatation and Curettage; Doubl | 2021 |
Articaine use does not routinely eliminate the need for palatal injections for primary maxillary molar extractions: a randomized cross-over clinical trial.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Child; Double-Blind Method; H | 2022 |
Effect of bupivacaine liposome suspension administered as a local anesthetic block on indicators of pain and distress during and after surgical castration in dairy calves.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cattle; Lidocaine; Liposomes; Male; Orchiectomy; Pain | 2022 |
Neuraxial administration of morphine combined with lidocaine induces regional antinociception in inland bearded dragons (Pogona vitticeps).
Topics: Animals; Cross-Over Studies; Lidocaine; Lizards; Morphine; Pain | 2021 |
Music as an adjunct to combination analgesia for neonatal circumcision: A randomized controlled trial.
Topics: Analgesia; Anesthetics, Local; Circumcision, Male; Humans; Infant; Infant, Newborn; Lidocaine; Lidoc | 2022 |
Pain Relief for Hysterosalpingography: A Randomized Controlled, Double Blinded Trial Comparing Suppository Diclofenac, Prilocaine/Lignocaine (EMLA) Cream And Placebo.
Topics: Diclofenac; Female; Humans; Hysterosalpingography; Lidocaine; Pain; Prilocaine; Prospective Studies | 2021 |
A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess.
Topics: Abscess; Administration, Intranasal; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Dra | 2022 |
Evaluating the Preemptive Analgesic Effect of Photo-biomodulation Therapy on Pain Perception During Local Anesthesia Injection in Children: A Split-mouth Triple-blind Randomized Controlled Clinical Trial.
Topics: Analgesics; Anesthesia, Local; Anesthetics, Local; Benzocaine; Child; Gels; Humans; Lidocaine; Mouth | 2022 |
The effects of target-controlled infusion of lidocaine undergoing vocal cord polypectomy: A randomized controlled trial (CONSORT compliant).
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Cough; Dose-Response Relationship, Drug; | 2022 |
Sexual communication mediates cognitive-behavioral couple therapy outcomes: A randomized clinical trial for provoked vestibulodynia.
Topics: Cognition; Communication; Couples Therapy; Female; Humans; Lidocaine; Pain; Personal Satisfaction; S | 2022 |
Effect of intravenous lidocaine on propofol consumption in elderly patients undergoing colonoscopy: a double-blinded, randomized, controlled trial.
Topics: Aged; Anesthetics, Intravenous; Colonoscopy; Double-Blind Method; Humans; Lidocaine; Pain; Propofol; | 2022 |
Efficacy of adding dexmedetomidine to lidocaine to enhance inferior alveolar nerve block in patients with asymptomatic irreversible pulpitis: double-blind randomized clinical trial.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Humans; Lidocai | 2022 |
The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media.
Topics: Acetaminophen; Acute Disease; Analgesics; Anti-Bacterial Agents; Child; Child, Preschool; Earache; H | 2022 |
Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial.
Topics: Adrenal Cortex Hormones; Adult; Anesthetics, Local; Arthralgia; Female; Humans; Injections, Intra-Ar | 2022 |
Comparison of Maxillary Lateral Incisor Infiltration Pain Using the Dentapen and a Traditional Syringe: A Prospective Randomized Study.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Humans; Incisor; Lidocaine; Pain; Prospective Studies | 2022 |
A comparison of ondansetron and lidocaine in reducing injection pain of propofol: a randomized controlled study.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Humans; | 2022 |
Effect of Systemic Lidocaine on Postoperative Early Recovery Quality in Patients Undergoing Supratentorial Tumor Resection.
Topics: Adult; Anesthetics, Local; Humans; Interleukin-6; Lidocaine; Pain; Saline Solution; Supratentorial N | 2022 |
Padded Dressing with Lidocaine HCL for Reducing Pain during Intravenous Cannulation in Adult Patients: A Randomized Controlled Clinical Trial.
Topics: Adult; Anesthetics, Local; Bandages; Catheterization; Humans; Lidocaine; Pain | 2022 |
Oral phenazopyridine vs intravesical lidocaine for bladder onabotulinumtoxinA analgesia: a randomized controlled trial.
Topics: Adult; Analgesia; Botulinum Toxins, Type A; Female; Humans; Lidocaine; Pain; Phenazopyridine; Treatm | 2022 |
Application of a Remotely Controlled Artificial Intelligence Analgesic Pump Device in Painless Treatment of Children.
Topics: Analgesics; Anesthetics, Local; Artificial Intelligence; Carticaine; Child; Double-Blind Method; Epi | 2022 |
Roller microneedles transdermal delivery of compound lidocaine cream for enhancing the analgesic effect: A randomized self-controlled trial.
Topics: Analgesics; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; M | 2022 |
Effect of Paracervical Block Volume on Pain Control for Dilation and Aspiration: A Randomized Controlled Trial.
Topics: Abortion, Induced; Abortion, Spontaneous; Anesthesia, Obstetrical; Anesthetics, Local; Dilatation; D | 2022 |
Comparison of the efficacy of intralesional 5-fluorouracil/lidocaine/epinephrine injection with cryotherapy to treat common and palmoplantar warts: A randomized, controlled trial.
Topics: Cryotherapy; Epinephrine; Fluorouracil; Humans; Injections, Intralesional; Lidocaine; Pain; Quality | 2022 |
Protocol for a multi-center randomized controlled trial to evaluate the benefits of exercise incentives and corticosteroid injections in osteoarthritis of the knee (MOVE-OK).
Topics: Adrenal Cortex Hormones; Aged; Exercise; Humans; Lidocaine; Multicenter Studies as Topic; Osteoarthr | 2022 |
Inferior alveolar nerve block success of 2% mepivacaine versus 4% articaine in patients with symptomatic irreversible pulpitis in mandibular molars: A randomized double-blind single-centre clinical trial.
Topics: Anesthetics, Local; Carticaine; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Mepivacain | 2022 |
Pretreatment with Low-Dose Esketamine for Reduction of Propofol Injection Pain: A Randomized Controlled Trial.
Topics: Anesthetics, Intravenous; Double-Blind Method; Humans; Ketamine; Lidocaine; Pain; Propofol | 2022 |
The application of xylocaine 10% pump-spray to improve immediate post-adenotonsillectomy pain in children: A randomized controlled trial.
Topics: Adenoidectomy; Adolescent; Analgesics; Analgesics, Opioid; Child; Child, Preschool; Double-Blind Met | 2022 |
Comparative Study of the Effect of Lidocaine Spray and Ice Spray on the Pain Intensity During Intramuscular Injection: A Randomized Clinical Trial.
Topics: Anesthetics, Local; Humans; Ice; Injections, Intramuscular; Lidocaine; Pain; Pain Measurement | 2023 |
Patient Comfort, Safety, and Effectiveness of Resilient Hyaluronic Acid Fillers Formulated With Different Local Anesthetics.
Topics: Anesthetics, Local; Cosmetic Techniques; Dermal Fillers; Double-Blind Method; Humans; Hyaluronic Aci | 2022 |
Can intravenous lidocaine definitely attenuate propofol requirement and improve outcomes among colonoscopic patients under intravenous sedation?: A double-blinded, randomized controlled trial.
Topics: Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Colonoscopy; Double-Blind Method; Humans; | 2022 |
A Randomized Controlled Trial Comparing Two Different Local Intraurethral Anesthetics in Optical Internal Urethrotomy at the Outpatient Clinic.
Topics: Ambulatory Care Facilities; Anesthetics, Local; Constriction, Pathologic; Humans; Lidocaine; Pain; P | 2022 |
Heat abatement during the pre-weaning period: effects on lying behavior and disbudding-related responses of male Holstein calves.
Topics: Animals; Cattle; Heat Stress Disorders; Horns; Lidocaine; Male; Pain; Weaning | 2022 |
Comparison of Intravenous Paracetamol, Dexketoprofen Trometamol, or Topical Lidocaine Use for Pain Relief in Scorpion Stings: A Placebo-Controlled, Randomized Study.
Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Huma | 2022 |
Rationale and design of a multicenter randomized clinical trial of vestibulodynia: understanding pathophysiology and determining appropriate treatments (vestibulodynia: UPDATe).
Topics: Antidepressive Agents, Tricyclic; Cytokines; Estradiol; Female; Humans; Lidocaine; MicroRNAs; Multic | 2022 |
Evaluation of pulpal anesthesia and injection pain using IANB with pre-heated, buffered and conventional 2% lignocaine in teeth with symptomatic irreversible pulpitis-a randomized clinical study.
Topics: Adult; Anesthetics, Local; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Pain; Pulpitis | 2022 |
Efficacy of femoral periarterial block in preventing thigh tourniquet pain: a randomized controlled trial.
Topics: Anesthetics, Local; Humans; Lidocaine; Pain; Pain, Postoperative; Thigh; Tourniquets | 2023 |
Transforaminal Versus Interlaminar Approach of Full-Endoscopic Lumbar Discectomy Under Local Anesthesia for L5/S1 Disc Herniation: A Randomized Controlled Trial.
Topics: Anesthesia, Local; Diskectomy; Diskectomy, Percutaneous; Endoscopy; Humans; Intervertebral Disc Disp | 2022 |
Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial.
Topics: Anesthetics, Local; Axilla; Hair Removal; Humans; Ice; Lasers, Semiconductor; Lidocaine; Lidocaine, | 2023 |
Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial.
Topics: Anesthetics, Local; Axilla; Hair Removal; Humans; Ice; Lasers, Semiconductor; Lidocaine; Lidocaine, | 2023 |
Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial.
Topics: Anesthetics, Local; Axilla; Hair Removal; Humans; Ice; Lasers, Semiconductor; Lidocaine; Lidocaine, | 2023 |
Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial.
Topics: Anesthetics, Local; Axilla; Hair Removal; Humans; Ice; Lasers, Semiconductor; Lidocaine; Lidocaine, | 2023 |
Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial.
Topics: Anesthetics, Local; Axilla; Hair Removal; Humans; Ice; Lasers, Semiconductor; Lidocaine; Lidocaine, | 2023 |
Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial.
Topics: Anesthetics, Local; Axilla; Hair Removal; Humans; Ice; Lasers, Semiconductor; Lidocaine; Lidocaine, | 2023 |
Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial.
Topics: Anesthetics, Local; Axilla; Hair Removal; Humans; Ice; Lasers, Semiconductor; Lidocaine; Lidocaine, | 2023 |
Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial.
Topics: Anesthetics, Local; Axilla; Hair Removal; Humans; Ice; Lasers, Semiconductor; Lidocaine; Lidocaine, | 2023 |
Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial.
Topics: Anesthetics, Local; Axilla; Hair Removal; Humans; Ice; Lasers, Semiconductor; Lidocaine; Lidocaine, | 2023 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor | 2023 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor | 2023 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor | 2023 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor | 2023 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor | 2023 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor | 2023 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor | 2023 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor | 2023 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketor | 2023 |
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies | 2023 |
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies | 2023 |
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies | 2023 |
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies | 2023 |
A comparative study of pain perception during the microfocused ultrasound procedure between topical anesthesia and combined topical anesthesia with forced air cooling.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Humans; Lidocaine; Pain; Pain Perception; Patient Sati | 2023 |
Compound lidocaine/prilocaine cream combined with tetracaine prevents cough caused by extubation after general anaesthesia: a randomised controlled trial.
Topics: Airway Extubation; Anesthesia, General; Anesthetics, Local; Cough; COVID-19; Double-Blind Method; Ep | 2023 |
Effectiveness of cryotherapy, sucrose solution and a combination therapy for pain control during local anesthesia in children: a split mouth study.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Child; Humans; Lidocaine; Mouth; Pain; Pa | 2022 |
Local anesthesia with SleeperOne S4 computerized device
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Child; Humans; Lidocaine; Pain; Pain Perc | 2023 |
Effect of 5% EMLA Cream on Postoperative Sore Throat in Adults Following General Endotracheal Anesthesia: A Randomized Placebo-Controlled Study.
Topics: Adolescent; Adult; Aged; Anesthesia, Endotracheal; Anesthesia, General; Anesthetics, Local; Cough; H | 2023 |
The Effectiveness of Facet Joint Injection with Steroid and Botulinum Toxin in Severe Lumbar Central Spinal Stenosis: A Randomized Controlled Trial.
Topics: Aged; Botulinum Toxins, Type A; Humans; Injections, Epidural; Lidocaine; Lumbar Vertebrae; Pain; Spi | 2022 |
Effect of Preoperative Oral Steroids in Comparison to Anti-inflammatory on Anesthetic Success of Inferior Alveolar Nerve Block in Mandibular Molars with Symptomatic Irreversible Pulpitis-A Double-blinded Randomized Clinical Trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents; Dexamethasone; Double-Blind Method | 2023 |
A Randomized Trial Comparing Intravenous Paracetamol, Topical Lidocaine, and Ice Application for Treatment of Pain Associated with Scorpion Stings: Some Concerns.
Topics: Acetaminophen; Humans; Ice; Lidocaine; Pain; Scorpion Stings | 2023 |
Cooling spray or lidocaine spray and needle insertion pain in hemodialysis patients: an open-label cross-over randomized clinical trial.
Topics: Cross-Over Studies; Dietary Supplements; Humans; Lidocaine; Pain; Renal Dialysis | 2023 |
Topical Lidocaine or Lidocaine/Diltiazem Ointment Following Rubber Band Ligation of Hemorrhoids: A Prospective 3-Armed Randomized Controlled Trial.
Topics: Adolescent; Adult; Diltiazem; Hemorrhoids; Hospitals, University; Humans; Lidocaine; Ointments; Pain | 2023 |
Comparing the effectiveness and lubricity of a novel Shea lubricant to 2% lidocaine gel for digital rectal examination: a randomized non-inferiority trial.
Topics: Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Lubricants; Pain; Single-Blind Method | 2023 |
Inferior Alveolar Nerve Block Plus Cryotherapy Anesthesia Success in Pulpectomy Of Primary Molars with Irreversible Pulpitis: a Randomized Clinical Trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Child; Cryotherapy; Double-Blind Method; Humans; | 2023 |
Investigating 3D-printed disk compressing against skin for pain relief in intradermal infiltration anesthesia: a randomized controlled trial.
Topics: Anesthesia, Local; Anesthetics, Local; Humans; Lidocaine; Pain; Printing, Three-Dimensional | 2023 |
Effects of lidocaine incorporation (without epinephrine) on pain and 2-week complications of botulinum toxin: a double-blind randomized placebo-controlled clinical trial.
Topics: Botulinum Toxins, Type A; Double-Blind Method; Epinephrine; Female; Humans; Lidocaine; Neuromuscular | 2023 |
Comparison of the Analgesic Efficacy of Lidocaine Spray versus Tramadol and Fentanyl for Pain Control in Rib Fractures.
Topics: Adult; Analgesics; Analgesics, Opioid; Anesthetics, Local; Fentanyl; Humans; Lidocaine; Middle Aged; | 2023 |
Effectiveness of buffered and non-buffered local anaesthetic in inferior alveolar nerve block: a randomised study.
Topics: Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Epinephrine; Humans; Lidocaine; Mandibul | 2023 |
Pulpal anesthesia of maxillary first molars using 4% articaine infiltration in patients with symptomatic irreversible pulpitis: a randomized controlled clinical trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Epinephrine; Humans; Lidoca | 2023 |
Comparison of intra-cuff lidocaine vs alkalinized lidocaine effects for prevention of post-operative sore throat.
Topics: Anesthesia, General; Cross-Sectional Studies; Female; Humans; Intubation, Intratracheal; Lidocaine; | 2022 |
Cryotherapy and pain intensity during endodontic treatment of mandibular first permanent molars with symptomatic irreversible pulpitis: A randomized controlled trial.
Topics: Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cryotherapy; Double-Blind Method; Humans; | 2023 |
Evaluation of primary wound healing and potential complications after perioperative infiltration with lidocaine without adrenaline in surgical incisions in dogs and cats.
Topics: Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Epinephrine; Lidocaine; Pain; Prospective Studies; | 2023 |
Prevention of pain on injection of propofol using ice gel pack versus pre-treatment with lignocaine: a randomized controlled trial.
Topics: Double-Blind Method; Humans; Ice; Injections, Intravenous; Lidocaine; Pain; Propofol | 2023 |
Pain Relief Durations of Different Concentrations of Lidocaine in Wide Awake Hand Surgery: A Prospective Randomised Clinical Trial.
Topics: Anesthesia, Local; Anesthetics, Local; Epinephrine; Hand; Humans; Lidocaine; Pain; Prospective Studi | 2023 |
Effect of lidocaine spray on reliving non-coring needle puncture-related pain in patients with totally implantable venous access port: a randomized controlled trial.
Topics: Anesthetics, Local; Catheterization, Central Venous; China; Humans; Lidocaine; Pain; Punctures | 2023 |
Nonsteroidal anti-inflammatory drug with a local anesthetic compared to nonsteroidal anti-inflammatory drug alone significantly reduce the pain associated with vaginoscopic office hysteroscopy.
Topics: Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents; Female; Humans; Hysteroscopy; Lidoc | 2023 |
Alkalized lidocaine in a tapered cuff suppresses endotracheal tube-induced hemodynamic changes: a randomized controlled trial.
Topics: Anesthetics, Local; Cough; Heart Rate; Humans; Intubation, Intratracheal; Lidocaine; Pain; Pharyngit | 2023 |
Intraoperative analgesic effect of intravertebral lidocaine injection during percutaneous kyphoplasty in the treatment of thoracolumbar compression fractures in elderly patients.
Topics: Aged; Analgesics; Bone Cements; Fractures, Compression; Humans; Kyphoplasty; Lidocaine; Osteoporotic | 2023 |
Topical Lidocaine And Or/ Intravenous Midazolam Before Radial Coronary Angiography To Prevent Radial Artery Spasm.
Topics: Cardiac Catheterization; Coronary Angiography; Female; Humans; Lidocaine; Male; Midazolam; Pain; Per | 2023 |
Comparative study of articaine 4% versus lidocaine 2% in the local anesthesia of permanent mandibular first molars affected by MIH: a randomized controlled trial.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Child; Double-Blind Method; H | 2023 |
A Clinical Trial on the Welfare Effects of Administering Meloxicam to 10 to 21 Day Dairy Calves Following Caustic Paste Disbudding.
Topics: Animal Welfare; Animals; Cattle; Caustics; Dinoprostone; Horns; Hydroxyl Radical; Inflammation; Lido | 2023 |
Placebo-controlled randomized double-blind comparison of the analgesic efficacy of lidocaine spray and etofenamate spray in pain control of rib fractures.
Topics: Analgesics; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Pain; Pain Management; Prosp | 2023 |
Articaine Infiltration Versus Lidocaine Inferior Alveolar Nerve Block for Primary Mandibular Molars: A Double-blind Randomized Controlled Clinical Trial.
Topics: Carticaine; Child; Humans; Lidocaine; Male; Mandibular Nerve; Molar; Pain | 2023 |
Articaine versus Lidocaine in only buccal infiltration anesthesia for the extraction of mandibular anterior teeth. A prospective split-mouth randomized-controlled clinical study.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Carticaine; Humans; Lidocaine; Mouth; Pain; Prospectiv | 2023 |
Effects of an intravenous lidocaine bolus before tracheal extubation on recovery after breast surgery - Lidocaine at the End (LATE) study: a randomized controlled clinical trial.
Topics: Airway Extubation; Breast Neoplasms; Female; Humans; Lidocaine; Pain; Pharyngitis; Postoperative Nau | 2023 |
Comparing the effectiveness of topical dexamethasone emollient, lidocaine gel, and glycerin emollient on the endotracheal tube for postoperative hoarseness of voice, sore throat, and laryngospasm.
Topics: Emollients; Glycerol; Hoarseness; Humans; Laryngismus; Lidocaine; Pain; Pharyngitis | 2023 |
[Functionality/isokinetic work of quadriceps in patients with gonarthrosis managed with prolotherapy].
Topics: Exercise Therapy; Humans; Lidocaine; Osteoarthritis, Knee; Pain; Prolotherapy; Treatment Outcome | 2023 |
Topical anaesthesia degree is reduced in temporomandibular disorders patients: A novel approach to assess underlying mechanisms of the somatosensory alterations.
Topics: Anesthesia, Local; Humans; Lidocaine; Pain; Pain Measurement; Pain Threshold; Temporomandibular Join | 2020 |
Randomized Controlled Trial to Assess the Impact of High Concentration Intraurethral Lidocaine on Urodynamic Voiding Parameters.
Topics: Administration, Topical; Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; | 2019 |
Lidocaine infusion has a 25% opioid-sparing effect on background pain after burns: A prospective, randomised, double-blind, controlled trial.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; A | 2020 |
The effectiveness of topical lidocaine in relieving pain related to intranasal midazolam sedation: a randomized, placebo-controlled clinical trial.
Topics: Administration, Intranasal; Child; Child, Preschool; Double-Blind Method; Humans; Lidocaine; Midazol | 2020 |
Intracervical block for levonorgestrel-releasing intrauterine system placement among nulligravid women: a randomized double-blind controlled trial.
Topics: Adult; Anesthetics, Local; Contraceptive Agents, Female; Double-Blind Method; Female; Gravidity; Hum | 2020 |
Efficacy of buffered local anaesthetics in head and neck infections.
Topics: Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Double-Blind Method; Female; Humans; H | 2019 |
Anesthesia Onset Time and Injection Pain Between Buffered and Unbuffered Lidocaine Used as Local Anesthetic for Dental Care in Children.
Topics: Anesthesia, Dental; Anesthetics, Local; Child; Dental Care; Double-Blind Method; Epinephrine; Humans | 2019 |
Liposomal anesthetic gel for pain control during periodontal therapy in adults: a placebo-controlled RCT.
Topics: Adult; Aged; Anesthesia, Dental; Anesthetics, Local; Chronic Periodontitis; Dental Scaling; Double-B | 2020 |
Comparison of the efficacy of eutectic mixture of local anesthetics (EMLA) and dorsal penile nerve block (DPNB) in neonatal circumcision.
Topics: Anesthesia, Local; Anesthetics, Local; Circumcision, Male; Humans; Infant; Infant, Newborn; Lidocain | 2019 |
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa - a randomized cross-over study.
Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cross-Over Studi | 2019 |
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa - a randomized cross-over study.
Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cross-Over Studi | 2019 |
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa - a randomized cross-over study.
Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cross-Over Studi | 2019 |
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa - a randomized cross-over study.
Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cross-Over Studi | 2019 |
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa - a randomized cross-over study.
Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cross-Over Studi | 2019 |
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa - a randomized cross-over study.
Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cross-Over Studi | 2019 |
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa - a randomized cross-over study.
Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cross-Over Studi | 2019 |
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa - a randomized cross-over study.
Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cross-Over Studi | 2019 |
Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa - a randomized cross-over study.
Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Child; Cross-Over Studi | 2019 |
Clinical effects of epidurally administered dexmedetomidine with or without lidocaine in sheep.
Topics: Anesthetics, Local; Animals; Blood Pressure; Dexmedetomidine; Drug Combinations; Female; Heart Rate; | 2020 |
Lidocaine-Prilocaine Cream Compared With Injected Lidocaine for Vulvar Biopsy: A Randomized Controlled Trial.
Topics: Aged; Anesthetics, Local; Biopsy, Needle; Female; Humans; Injections; Lidocaine; Lidocaine, Prilocai | 2020 |
Efficacy of lidocaine 7 %, tetracaine 7 % self-occlusive cream in reducing MAL-cPDT-associated pain in subjects with actinic keratosis: A randomized, single-blind, vehicle-controlled trial (The "3P-Trial").
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Drug Combinations; Female; Humans; Keratosis, Actinic; | 2020 |
Reduction in pain from corticosteroid injection for the treatment of trigger finger with subcutaneous single-injection digital block: a randomized controlled trial.
Topics: Adrenal Cortex Hormones; Humans; Injections, Subcutaneous; Lidocaine; Pain; Trigger Finger Disorder | 2021 |
Reduced pain with injection of hyaluronic acid with pre-incorporated lidocaine for nasolabial fold correction: A multicenter, double-blind, randomized, active-controlled, split-face designed, clinical study.
Topics: Cosmetic Techniques; Dermal Fillers; Double-Blind Method; Humans; Hyaluronic Acid; Lidocaine; Nasola | 2020 |
Behavioral changes in calves 11 days after cautery disbudding: Effect of local anesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Cattle; Cautery; Female; Horns; Lidocaine; Pain; Pai | 2020 |
10% lidocaine spray for pain control during intrauterine device insertion: a randomised, double-blind, placebo-controlled trial.
Topics: Anesthetics, Local; Female; Humans; Intrauterine Devices; Lidocaine; Pain; Pain Management | 2021 |
10% lidocaine spray for pain control during intrauterine device insertion: a randomised, double-blind, placebo-controlled trial.
Topics: Anesthetics, Local; Female; Humans; Intrauterine Devices; Lidocaine; Pain; Pain Management | 2021 |
10% lidocaine spray for pain control during intrauterine device insertion: a randomised, double-blind, placebo-controlled trial.
Topics: Anesthetics, Local; Female; Humans; Intrauterine Devices; Lidocaine; Pain; Pain Management | 2021 |
10% lidocaine spray for pain control during intrauterine device insertion: a randomised, double-blind, placebo-controlled trial.
Topics: Anesthetics, Local; Female; Humans; Intrauterine Devices; Lidocaine; Pain; Pain Management | 2021 |
Cryoanalgesic versus EMLA® cream to reduced pain during analgesic injection in upper eyelid surgery: a randomized trial.
Topics: Analgesics; Anesthesia, Local; Anesthetics, Local; Eyelids; Humans; Lidocaine; Lidocaine, Prilocaine | 2021 |
Maxillary Lateral Incisor Injection Pain Using the Dentapen Electronic Syringe.
Topics: Anesthesia, Dental; Anesthetics, Local; Electronics; Humans; Incisor; Lidocaine; Pain; Syringes | 2020 |
Effect of low-dose lidocaine on objective upper extremity strength and immediate pain relief following cervical interlaminar epidural injections: a double-blinded randomized controlled trial.
Topics: Female; Humans; Injections, Epidural; Lidocaine; Middle Aged; Pain; Treatment Outcome; Upper Extremi | 2020 |
Addition of Lidocaine to the Distension Medium in Hysteroscopy Decreases Pain during the Procedure-A Randomized Double-blind, Placebo-controlled Trial.
Topics: Anesthetics, Local; Double-Blind Method; Female; Humans; Hysteroscopy; Lidocaine; Pain; Pain Measure | 2021 |
Pre-emptive topical lidocaine 5% plaster for prevention of post-craniotomy pain: a protocol for a multicentred, randomized, triple-blind, placebo-controlled clinical trial.
Topics: Anesthetics, Local; Craniotomy; Double-Blind Method; Humans; Lidocaine; Multicenter Studies as Topic | 2020 |
[Effects of double-catheter epidural analgesia by lidocaine injection respectively on the delivery outcomes and maternal-infant complications for persistent posterior or lateral occipital position of protracted active phase].
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthesia, Epidural; Cesarean Section; Delivery | 2020 |
Apical peri-prostatic nerve block versus intra-rectal xylocaine gel for trans- rectal ultrasound guided prostate biopsy among Nigerian patients: A prospective randomized study.
Topics: Administration, Rectal; Aged; Anesthetics, Local; Biopsy, Needle; Humans; Image-Guided Biopsy; Lidoc | 2020 |
Alkalinized lidocaine solution as a first-line local anesthesia protocol for intradetrusor injection of onabotulinum toxin A: Results from a double-blinded randomized controlled trial.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Botulinum Toxins, | 2020 |
Efficacy of precisely injected single local bolus of lignocaine for alleviation of behavioural responses to pain during tail docking and castration of lambs with rubber rings.
Topics: Amputation, Surgical; Anesthetics, Local; Animals; Behavior, Animal; Cohort Studies; Female; Injecti | 2020 |
Safety and Effectiveness of Hyaluronic Acid Fillers With Lidocaine for Full-Face Treatment in Asian Patients.
Topics: Adult; Asian People; Dermal Fillers; Drug Combinations; Esthetics; Female; Humans; Hyaluronic Acid; | 2020 |
Transnasal Flexible Laryngoscopy Using Different Topical Preparations and Methods of Application-A Randomized Study.
Topics: Administration, Topical; Anesthetics, Local; Humans; Laryngoscopy; Lidocaine; Pain; Prospective Stud | 2022 |
Median Effective Dose of Lidocaine for the Prevention of Pain Caused by the Injection of Propofol Formulated with Medium- and Long-Chain Triglycerides Based on Lean Body Weight.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Body Weight; Double-Blind Method; Humans; Lidocaine; P | 2021 |
Analgesic Efficacy of Intrauterine Lidocaine Flushing in Hysterosalpingo-foam Sonography: A Double-blind Randomized Controlled Trial.
Topics: Analgesics; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Pain; Pregnancy; Ult | 2021 |
Self-administrated vaginal 2% lidocaine in-situ gel for pain relief during copper intrauterine device insertion in women with previous caesarean delivery only: a randomised, double-blind placebo-controlled trial.
Topics: Adult; Anesthetics, Local; Cesarean Section; Double-Blind Method; Female; Gels; Humans; Intrauterine | 2021 |
Anorectal application of 5% lidocaine cream reduces pain prior to periprostatic nerve block during transrectal ultrasound guided prostate biopsy: Randomized, prospective controlled study.
Topics: Administration, Rectal; Aged; Anesthesia, Rectal; Anesthetics, Local; Biopsy; Humans; Lidocaine; Mal | 2021 |
Effects of Valsalva Maneuver, EMLA Cream, and Stress Ball for Pregnant Women's Venipuncture Pain.
Topics: Anesthetics, Local; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain; Phlebot | 2021 |
Randomised controlled trial of a microneedle patch with a topical anaesthetic for relieving the pain of dental injections.
Topics: Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Pain; Quality of Life | 2021 |
Intralesional corticosteroid injections are less painful without local anesthetic: a double-blind, randomized controlled trial.
Topics: Adrenal Cortex Hormones; Anesthetics, Local; Double-Blind Method; Epinephrine; Humans; Injections, I | 2022 |
Efficacy of compound topical anesthesia combined with photobiomodulation therapy in pain control for placement of orthodontic miniscrew: a double-blind, randomized clinical trial.
Topics: Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Low-Level Lig | 2022 |
Lidocaine coinfusion alleviates vascular pain induced by hypertonic saline infusion: a randomized, placebo-controlled trial.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Male; Pain; Prospective S | 2021 |
Does intravenous lidocaine added to nonsteroidal anti-inflammatory drugs reduce pain during colposcopy? A prospective randomized double-blind study.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Colposcopy; Do | 2021 |
Lidocaine before esophageal manometry and ambulatory pH monitoring: A randomized controlled trial.
Topics: Administration, Intranasal; Adult; Aged; Anesthetics, Local; Double-Blind Method; Esophageal Motilit | 2021 |
Cognitive-behavioral couple therapy versus lidocaine for provoked vestibulodynia: A randomized clinical trial.
Topics: Adult; Anxiety; Catastrophization; Cognitive Behavioral Therapy; Couples Therapy; Female; Humans; In | 2021 |
Comparing Vestibule Examination Techniques: Light Touch, Serial Forces, and the Lidocaine Test.
Topics: Adult; Anesthetics, Local; Female; Humans; Lidocaine; Oregon; Pain; Pain Measurement; Touch; Vulva; | 2021 |
Use of Lidocaine Cream for Pain Management During Immunizations of Infants at an Urban Health Clinic.
Topics: Anesthetics, Local; Child; Double-Blind Method; Humans; Immunization; Infant; Lidocaine; Pain; Pain | 2022 |
Utility of nasal application of lignocaine gel using cotton tip swab versus squirting with slip-tip syringe for transnasal fibreoptic bronchoscopy: a pilot randomised controlled trial.
Topics: Bronchoscopy; Epistaxis; Humans; Lidocaine; Pain; Pilot Projects; Syringes | 2022 |
Comparing the effectiveness of three pain relief methods for inserting a needle into the implanted venous access chemoport: A randomized controlled trial.
Topics: Anesthetics, Local; Humans; Lidocaine; Neoplasms; Pain; Pain Measurement | 2022 |
Assessment of clinical efficacy of lidocaine/tetracaine 7%/7% peel cream in fractional microablative laser procedure-associated pain for facial skin aging treatment. A randomized, controlled, single-blind trial.
Topics: Adult; Anesthetics, Local; Emollients; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Prospecti | 2022 |
'Pain-free TRUS B': a phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography-guided prostate biopsy (ANZUP 1501).
Topics: Anesthesia, Local; Anesthetics, Local; Biopsy; Humans; Lidocaine; Male; Methoxyflurane; Pain; Pain M | 2022 |
A Comparison of Paracervical Block Volumes Before Osmotic Dilator Placement: A Randomized Controlled Trial.
Topics: Abortion, Induced; Adult; Anesthetics, Local; Cervix Uteri; Female; Humans; Lidocaine; Pain; Pain Me | 2021 |
Pain thresholds, supra-threshold pain and lidocaine sensitivity in patients with erythromelalgia, including the I848Tmutation in Na
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Dose-Response Relationship, Drug; Double-Blind M | 2017 |
Core needle breast biopsy with local dental anesthetics.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Biopsy, Large-Core Needle; Breast Neoplas | 2017 |
Intravenous Lidocaine Alleviates the Pain of Propofol Injection by Local Anesthetic and Central Analgesic Effects.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Central Nervous System; Double-Blind Method; Fe | 2018 |
A Randomized Control Trial Comparing Combined Glandular Lidocaine Injection and Intraurethral Lidocaine Gel with Intraurethral Lidocaine Gel Alone in Cystoscopy and Urethral Dilatation.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Cystoscopy; Dilatation; Double-Blind Method; Gel | 2017 |
Evaluation of Paracervical Block and IV Sedation for Pain Management during Hysteroscopic Polypectomy: A Randomized Clinical Trial.
Topics: Adult; Anesthesia, Obstetrical; Female; Fentanyl; Humans; Hysteroscopy; Iran; Lidocaine; Middle Aged | 2017 |
Does the Application of Heat Gel Pack After Eutectic Mixture of Local Anesthetic Cream Improve Venipuncture or Intravenous Cannulation Success Rate in Children? A Randomized Control Trial.
Topics: Anesthetics, Local; Child; Child, Preschool; Female; Hot Temperature; Humans; Lidocaine; Lidocaine, | 2018 |
Direct shoulder magnetic resonance arthrography for superior labral anterior-to-posterior (SLAP) and Bankart lesions: investigation into the appropriate dose and level of local anesthesia.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Arthrography; Bankart Lesions; Female; Humans; Lidocai | 2017 |
Which is more effective for pain relief during fractionated carbon dioxide laser treatment: EMLA cream or forced cold air anesthesia?
Topics: Ablation Techniques; Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Cryotherapy; Face; Fe | 2018 |
A randomized double-blind controlled trial comparing three sedation regimens during flexible bronchoscopy: Dexmedetomidine, alfentanil and lidocaine.
Topics: Adolescent; Adult; Aged; Alfentanil; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Loca | 2018 |
Preventive effect of a vapocoolant spray on propofol-induced pain: a prospective, double-blind, randomized study.
Topics: Adult; Analgesia; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle A | 2017 |
Topic anaesthesia with a eutectic mixture of lidocaine/prilocaine cream after elective caesarean section: a randomised, placebo-controlled trial.
Topics: Adult; Analgesics; Anesthesia, Local; Anesthetics, Local; Cesarean Section; Double-Blind Method; Dru | 2017 |
Pain During Venous Cannulation.
Topics: Adult; Aged; Anesthetics, Local; Catheterization; Female; Humans; Lidocaine; Male; Middle Aged; Pain | 2017 |
γ-Aminobutyric acid (GABA) oral rinse reduces capsaicin-induced burning mouth pain sensation: An experimental quantitative sensory testing study in healthy subjects.
Topics: Adult; Analgesics; Capsaicin; Cross-Over Studies; Double-Blind Method; Female; gamma-Aminobutyric Ac | 2018 |
Combination Analgesia for Neonatal Circumcision: A Randomized Controlled Trial.
Topics: Analgesia; Anesthetics, Local; Circumcision, Male; Double-Blind Method; Drug Therapy, Combination; F | 2017 |
Comparison of three analgesic drug regimens with twelfth subcostal nerve block for pain control during extracorporeal shock wave lithotripsy.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; | 2018 |
Randomized Clinical Trial of Lidocaine Analgesia for Transurethral Bladder Catheterization Delivered via Blunt Tipped Applicator in Young Children.
Topics: Analgesia; Anesthetics, Local; Child, Preschool; Emergency Service, Hospital; Female; Humans; Infant | 2018 |
EMLA cream does not influence efficacy and pain reduction during pulsed-dye laser treatment of port-wine stain: a prospective side-by-side comparison.
Topics: Female; Humans; Lasers, Dye; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; P | 2018 |
Lidocaine Spray Versus Paracervical Block During Loop Electrosurgical Excision Procedure: A Randomized Trial.
Topics: Adult; Aerosols; Aged; Anesthesia, Local; Anesthesia, Obstetrical; Anesthetics, Local; Cervix Uteri; | 2018 |
Anaesthetic efficacy of 4% articaine and 2% lidocaine for extraction and pulpotomy of mandibular primary molars: an equivalence parallel prospective randomized controlled trial.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Child; Child, Preschool; Fema | 2018 |
Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial.
Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle A | 2018 |
Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial.
Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle A | 2018 |
Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial.
Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle A | 2018 |
Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial.
Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle A | 2018 |
Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial.
Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle A | 2018 |
Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial.
Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle A | 2018 |
Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial.
Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle A | 2018 |
Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial.
Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle A | 2018 |
Comparison of Two Lidocaine Administration Techniques on Perceived Pain From Bedside Procedures: A Randomized Clinical Trial.
Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle A | 2018 |
[The Effect of Pain Relieving Intervention During Infiltration among Gamma Knife Surgery Patients for Stereotactic Frame Fixation].
Topics: Aged; Anesthetics, Local; Blood Pressure; Female; Heart Rate; Humans; Hypothermia, Induced; Lidocain | 2018 |
Intravenous Lidocaine Provides Similar Analgesia to Intravenous Morphine for Undifferentiated Severe Pain in the Emergency Department: A Pilot, Unblinded Randomized Controlled Trial.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Emergency Medical Services; Emergency Service, Hospit | 2019 |
A Randomized Clinical Trial Evaluating Rubber Dam Clamp Pain Reduction from a New Topical Liposomal Anesthetic Gel.
Topics: Anesthetics, Local; Child; Dental Anxiety; Dental Caries; Female; Gels; Humans; Lidocaine; Liposomes | 2018 |
Syringes versus Chinese cups in harvesting suction-induced blister graft: a randomized split-body study.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Blister; Bupivacaine; Female; Humans; Lidocaine; Male; | 2018 |
Pain and outcomes of carpal tunnel release under local anaesthetic with or without a tourniquet: a randomized controlled trial.
Topics: Anesthesia, Local; Anesthetics, Local; Carpal Tunnel Syndrome; Decompression, Surgical; Disability E | 2018 |
Use of a vibrating kinetic anesthesia device reduces the pain of lidocaine injections: A randomized split-body trial.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Female; Humans; Injections; Lidocaine; Male; Mid | 2019 |
Effect of the addition of epinephrine to a lidocaine solution on the efficacy and duration of palmar digital nerve blocks in horses with naturally occurring forefoot lameness.
Topics: Anesthetics, Local; Animals; Cross-Over Studies; Drug Therapy, Combination; Epinephrine; Foot Diseas | 2018 |
Accuracy and efficacy of ultrasound-guided pes anserinus bursa injection.
Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Bursa, Synovial; Bursitis; Female; Humans | 2019 |
[Comparison between Dexmedetomidine and Fentanyl Infusion during Fetoscopic Laser Photocoagulation for Twin to Twin Transfusion Syndrome].
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Dexmedetomidine; Female; Fentanyl; Fetofetal T | 2017 |
Efficacy of Articaine Versus Lidocaine Administered as Supplementary Intraligamentary Injection after a Failed Inferior Alveolar Nerve Block: A Randomized Double-blind Study.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Female; Humans; Inje | 2019 |
Magnesium Sulfate as Adjuvant in Prehospital Femoral Nerve Block for a Patient with Diaphysial Femoral Fracture: A Randomized Controlled Trial.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Local; Double-Blind Met | 2018 |
The use of cold therapy, music therapy and lidocaine spray for reducing pain and anxiety following chest tube removal.
Topics: Chest Tubes; Cryotherapy; Device Removal; Humans; Lidocaine; Music Therapy; Pain; Pain Management | 2019 |
Inferior Alveolar Nerve Block Injection Pain Using a Computer-Controlled Local Anesthetic Device (CCLAD): A Prospective, Randomized Study.
Topics: Adult; Anesthetics, Local; Cross-Over Studies; Equipment Design; Female; Humans; Injections; Lidocai | 2018 |
The analgesic efficacy and duration of lidocaine on vascular pain induced by hypertonic saline infusion: a double-blinded, randomized control trial.
Topics: Adult; Analgesics; Anesthetics, Local; Double-Blind Method; Female; Humans; Incidence; Lidocaine; Ma | 2019 |
Efficacy of Topical Vibratory Stimulation for Reducing Pain During Trigger Point Injection to the Gastrocnemius: A Randomized Controlled Trial.
Topics: Adult; Aged; Anesthetics, Local; Double-Blind Method; Female; Humans; Injections, Intramuscular; Lid | 2019 |
Evaluation of Neosaxitoxin as a local anesthetic during piglet castration: A potential alternative for Lidocaine.
Topics: Anesthetics, Local; Animals; Inflammation; Lidocaine; Male; Orchiectomy; Pain; Prospective Studies; | 2019 |
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antacids; Diphenhydramine; Double-Blind Met | 2019 |
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antacids; Diphenhydramine; Double-Blind Met | 2019 |
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antacids; Diphenhydramine; Double-Blind Met | 2019 |
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antacids; Diphenhydramine; Double-Blind Met | 2019 |
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antacids; Diphenhydramine; Double-Blind Met | 2019 |
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antacids; Diphenhydramine; Double-Blind Met | 2019 |
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antacids; Diphenhydramine; Double-Blind Met | 2019 |
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antacids; Diphenhydramine; Double-Blind Met | 2019 |
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antacids; Diphenhydramine; Double-Blind Met | 2019 |
Lidocaine and phenylephrine versus saline placebo nasal spray for the pain and distress of nasogastric tube insertion in young children and infants: a randomised, double-blind, controlled trial.
Topics: Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Female; Humans; Infant; Intubation | 2019 |
Behavioural alterations in piglets after surgical castration: Effects of analgesia and anaesthesia.
Topics: Analgesia; Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Lidocaine | 2019 |
Comparison of analgesic techniques in MRI-guided in-bore prostate biopsy.
Topics: Aged; Aged, 80 and over; Analgesia; Anesthetics, Local; Biopsy, Large-Core Needle; Humans; Lidocaine | 2019 |
Efficacy of pethidine, ketorolac, and lidocaine gel as analgesics for pain control in shockwave lithotripsy: A single-blinded randomized controlled trial.
Topics: Adult; Analgesia; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non- | 2019 |
Short communication: Assessment of disbudding pain in dairy calves using nonlinear measures of heart rate variability.
Topics: Anesthetics, Local; Animals; Cattle; Female; Heart Rate; Horns; Lidocaine; Meloxicam; Pain; Pain Mea | 2019 |
Short versus long-acting local anaesthetic in open carpal tunnel release: which provides better preemptive analgesia in the first 24 hours?
Topics: Adult; Aged; Aged, 80 and over; Amides; Analgesia; Anesthesia, Local; Anesthetics, Local; Carpal Tun | 2013 |
Technical effects of adding 1 % lidocaine to technetium sulfur colloid for sentinel lymphatic mapping in early breast cancer: analysis of data from a double-blind randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Breast Neoplasms; Double-Blind Method; Female; H | 2013 |
Anesthetic efficacy of a combination of 0.5 M mannitol plus 127.2 mg of lidocaine with 50 μg epinephrine in inferior alveolar nerve blocks: a prospective randomized, single-blind study.
Topics: Adult; Anesthetics, Local; Bicuspid; Chemistry, Pharmaceutical; Cross-Over Studies; Dental Pulp; Den | 2013 |
A prospective randomized trial comparing three different analgesic techniques for pain control during transrectal ultrasound guided prostate biopsy: a single center experience.
Topics: Administration, Rectal; Aged; Analgesia; Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; | 2013 |
The evaluation of hyaluronic acid, with and without lidocaine, in the filling of nasolabial folds as measured by ultrastructural changes and pain management.
Topics: Adult; Aged; Anesthetics, Local; Cosmetic Techniques; Double-Blind Method; Female; Follow-Up Studies | 2013 |
A randomized controlled study to compare the 2% lignocaine and aqueous lubricating gels for female urethral catheterization.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; Gels; Humans; Inpat | 2014 |
Faster onset and more comfortable injection with alkalinized 2% lidocaine with epinephrine 1:100,000.
Topics: Adult; Aged; Alkalies; Anesthesia, Dental; Anesthetics, Local; Buffers; Cross-Over Studies; Dental P | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Elective Surgical Procedures; Femal | 2013 |
Lidocaine-prilocaine (EMLA(®) ) cream as analgesia in hysteroscopy practice: a prospective, randomized, non-blinded, controlled study.
Topics: Anesthetics, Local; Cervix Uteri; Female; Humans; Hysteroscopy; Lidocaine; Lidocaine, Prilocaine Dru | 2013 |
The effect of sonophoresis on topical anesthesia: a pilot project.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Cuspid; Humans; Keratinocytes; Lid | 2013 |
A randomized trial of buffered versus nonbuffered lidocaine with epinephrine for cervical loop excision.
Topics: Adolescent; Adult; Anesthetics, Local; Buffers; Double-Blind Method; Electrosurgery; Epinephrine; Fe | 2014 |
Effect of alkalinisation of lignocaine for propofol injection pain: a prospective, randomised, double-blind study.
Topics: Adolescent; Adult; Alkalies; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Fema | 2013 |
Effectiveness of a topical local anaesthetic spray as analgesia for dressing changes: a double-blinded randomised pilot trial comparing an emulsion with an aqueous lidocaine formulation.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Bandages; Burns; Double-Blind Method; Emulsion | 2014 |
The effectivity of periprostatic nerve blockade for the pain control during transrectal ultrasound guided prostate biopsy.
Topics: Adenocarcinoma; Administration, Rectal; Aged; Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; | 2013 |
Comparison of three methods of preventing rocuronium induced pain on injection using venous occlusion technique: a randomized prospective double blind controlled study.
Topics: Adult; Aged; Androstanols; Double-Blind Method; Female; Fentanyl; Humans; Injections, Intravenous; L | 2013 |
Evaluation of the efficacy of a combination of diltiazem and periprostatic nerve block in pain control during transrectal ultrasonography-guided biopsy of the prostate.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Calcium Channel Blocke | 2013 |
Phase III, randomized, double-blind, placebo-controlled trial of topical 2 % lidocaine for the prevention and treatment of oral mucosal pain in children.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Double-Blind Method; Female; Humans; | 2014 |
Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children: a randomized controlled trial.
Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Child; Child, Preschool; Drug Combination | 2013 |
Lidocaine spray compared with submucosal injection for reducing pain during loop electrosurgical excision procedure: a randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Analgesia; Anesthetics, Local; Electrosurgery; Female; Humans; Injec | 2013 |
Comparison of cooling and EMLA to reduce the burning pain during capsaicin 8% patch application: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Capsaicin; Cryotherapy; Double-Blind Method; Female; Follow-Up Studies; Humans; Lidocaine; Li | 2013 |
Palpation versus ultrasound-guided corticosteroid injections and short-term effect in the distal radioulnar joint disorder: a randomized, prospective single-blinded study.
Topics: Adrenal Cortex Hormones; Adult; Aged; Female; Humans; Injections, Intra-Articular; Lidocaine; Male; | 2014 |
Topical anesthesia mitigates the pain of castration in beef calves.
Topics: Anesthesia, Local; Animal Welfare; Animals; Anti-Infective Agents, Local; Behavior, Animal; Bupivaca | 2013 |
Higher dose cervical 2% lidocaine gel for IUD insertion: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Gels; Humans; Intrauterine Devices; Lidocain | 2013 |
Higher dose cervical 2% lidocaine gel for IUD insertion: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Gels; Humans; Intrauterine Devices; Lidocain | 2013 |
Higher dose cervical 2% lidocaine gel for IUD insertion: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Gels; Humans; Intrauterine Devices; Lidocain | 2013 |
Higher dose cervical 2% lidocaine gel for IUD insertion: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Gels; Humans; Intrauterine Devices; Lidocain | 2013 |
Quality of life in patients with endometriosis and the effect of pertubation with lidocaine - a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Endometriosis; Female; Humans; Lidocaine; Pain; Pain | 2013 |
Comparing the efficacy of intrauterine lidocaine and paracervical block in decreasing the pain associated with endometrial biopsy: a randomised trial.
Topics: Adult; Anesthesia, Obstetrical; Anesthetics, Local; Biopsy; Endometrium; Female; Humans; Lidocaine; | 2014 |
Comparative study between three analgesic agents for the pain management during extracorporeal shock wave lithotripsy.
Topics: Adult; Analgesia; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; H | 2013 |
Buffered lidocaine for incision and drainage: a prospective, randomized double-blind study.
Topics: Adult; Aged; Anesthetics, Local; Buffers; Dental Pulp Necrosis; Dissection; Double-Blind Method; Dra | 2013 |
Reducing the pain of microemulsion propofol injections: a double-blind, randomized study of three methods of tourniquet and lidocaine.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; | 2013 |
Analgesic and anti-hyperalgesic effects of muscle injections with lidocaine or saline in patients with fibromyalgia syndrome.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Fibromyalgia; Humans; Hyperalgesia; Injectio | 2014 |
The effects of Valsalva maneuver on venipuncture pain in children: comparison to EMLA(®) (lidocaine-prilocaine cream).
Topics: Anesthetics, Local; Child; Drug Combinations; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug | 2014 |
The importance of anatomical region of local anesthesia for prostate biopsy; a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Biopsy; Humans; Lidocaine; Lower Uri | 2013 |
Comparison of anaesthetic and analgesic effects of emulsified isoflurane used alone or combined with lidocaine and fentanyl in dogs.
Topics: Analgesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Animals; Dogs; Dru | 2014 |
Can the addition of a paracervical block to systemic or local analgesics improve the pain perceived by the patient during hysterosalpingography?
Topics: Adolescent; Adult; Anesthesia, Local; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Meth | 2014 |
Randomised controlled trials may underestimate drug effects: balanced placebo trial design.
Topics: Female; Humans; Lidocaine; Male; Pain; Placebos; Saline Solution, Hypertonic; Young Adult | 2014 |
Comparison of postoperative redness of eyes after sub-Tenon's block and topical anaesthesia following phacoemulsification cataract surgery.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Eye Hemorrhage; Female; Humans; Lidocaine; Male; Nerve | 2014 |
Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, and paracervical block application for pain relief during suction termination of first-trimester pregnancy.
Topics: Abortion, Induced; Acetaminophen; Administration, Intravenous; Administration, Oral; Adult; Anesthes | 2013 |
EMLA(R) cream: a pain-relieving strategy for childhood vaccination.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Double- | 2014 |
EMLA(R) cream: a pain-relieving strategy for childhood vaccination.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Double- | 2014 |
EMLA(R) cream: a pain-relieving strategy for childhood vaccination.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Double- | 2014 |
EMLA(R) cream: a pain-relieving strategy for childhood vaccination.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Double- | 2014 |
Effect of intraurethral dwell time of local anesthetic jelly on pain perception in men undergoing outpatient rigid cystoscopy: a randomized prospective study.
Topics: Administration, Topical; Adult; Aged; Ambulatory Care; Anesthesia, Local; Anesthetics, Local; Cystos | 2014 |
Cisatracurium pretreatment with tourniquet reduces propofol injection pain: a double-blind randomized controlled trial.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Atracuri | 2014 |
Intravenous lidocaine pretreatment with venous occlusion for reducing microemulsion propofol induced pain: comparison of three doses of lidocaine.
Topics: Administration, Intravenous; Adult; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Metho | 2014 |
Liquid paraffin is superior to 2% lidocaine gel in reducing urethral pain during urodynamic study in men: A pilot study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Diagnostic Techniques, Urologi | 2015 |
Preemptive dexmedetomidine to prevent propofol injection pain in children.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Child; Child, Preschool; Dexmedetomidine; Double-Blind | 2015 |
Pretreatment with remifentanil, fentanyl, or lidocaine to prevent withdrawal after rocuronium using venous occlusion technique in children and adolescents: a prospective randomized placebo-controlled double-blind study.
Topics: Adolescent; Androstanols; Anesthesia, General; Child; Child, Preschool; Double-Blind Method; Female; | 2014 |
Injectable lidocaine provides similar analgesia compared to transdermal lidocaine/tetracaine patch for the incision and drainage of skin abscesses: a randomized, controlled trial.
Topics: Abscess; Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Female; Huma | 2014 |
Use of local anesthesia in transrectal ultrasound guided prostatic biopsy.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Humans; Image-Guided Biopsy; Lidocaine; Male; Middle Ag | 2014 |
Evaluating the hematoma block as an adjunct to procedural sedation for closed reduction of distal forearm fractures.
Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Conscious Sedation; Double-Blind Method; Fe | 2014 |
A randomized trial of epidural glucocorticoid injections for spinal stenosis.
Topics: Aged; Anesthetics, Local; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; H | 2014 |
A randomized trial of epidural glucocorticoid injections for spinal stenosis.
Topics: Aged; Anesthetics, Local; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; H | 2014 |
A randomized trial of epidural glucocorticoid injections for spinal stenosis.
Topics: Aged; Anesthetics, Local; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; H | 2014 |
A randomized trial of epidural glucocorticoid injections for spinal stenosis.
Topics: Aged; Anesthetics, Local; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; H | 2014 |
Efficacy of the Greater Occipital Nerve Block for Cervicogenic Headache: Comparing Classical and Subcompartmental Techniques.
Topics: Adult; Anesthetics, Local; Autonomic Nerve Block; Female; Humans; Lidocaine; Male; Middle Aged; Pain | 2015 |
Ultrasound-guided hematoma block in distal radial fracture reduction: a randomised clinical trial.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Female; Hematoma; Humans; Lidocaine; Male; Manipulatio | 2015 |
Is a retention time after the instillation of anesthetic lubricant necessary when performing male flexible cystoscopy?
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Clinical Co | 2015 |
Efficacy of the jet injector in local anaesthesia for small wound sutures: a randomised clinical trial compared with the needle infiltration technique.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Facial Injuries; Female; Humans; | 2015 |
A preliminary study of painless and effective transdermal botulinum toxin A delivery by jet nebulization for treatment of primary hyperhidrosis.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Botulinum Toxins, Type A; Drug Delivery System | 2014 |
Magnesium sulfate with lidocaine for preventing propofol injection pain: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; D | 2015 |
Pain sensation and injection techniques in maxillary dento-alveolar surgery procedures in children--a comparison between conventional and computerized injection techniques (The Wand).
Topics: Adolescent; Anesthesia, Dental; Anesthetics, Inhalation; Anesthetics, Local; Bicuspid; Child; Consci | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Intrauterine lidocaine for pain control during laminaria insertion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; | 2014 |
Does the combination of 3% mepivacaine plain plus 2% lidocaine with epinephrine improve anesthesia and reduce the pain of anesthetic injection for the inferior alveolar nerve block? A prospective, randomized, double-blind study.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Bicuspid; Dental P | 2014 |
Comparison of intravenous lidocaine versus morphine in alleviating pain in patients with critical limb ischaemia.
Topics: Administration, Intravenous; Adult; Aged; Analgesics, Opioid; Critical Illness; Double-Blind Method; | 2015 |
Procedural sedation and analgesia as an adjunct to periprostatic nerve block for prostate biopsy: A prospective randomized trial.
Topics: Aged; Anesthetics, Local; Biopsy; Gels; Humans; Hypnotics and Sedatives; Lidocaine; Male; Midazolam; | 2015 |
Safety and efficacy of various concentrations of topical lidocaine gel for intravitreal injection.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Conjunctiva; Cornea; Dose-Resp | 2014 |
[Effectiveness of local cooling and lidocaine administration for prevention of pain upon injection of propofol].
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Cryotherapy; Female; | 2014 |
The use of skin needling for the delivery of a eutectic mixture of local anesthetics.
Topics: Administration, Cutaneous; Adolescent; Adult; Anesthetics, Combined; Anesthetics, Local; Drug Delive | 2014 |
Anesthetic comparisons of 4% concentrations of articaine, lidocaine, and prilocaine as primary buccal infiltrations of the mandibular first molar: a prospective randomized, double-blind study.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Cross-Over Studies; Dental Pulp; Double-B | 2014 |
Effect of intracervical anesthesia on pain associated with the insertion of the levonorgestrel-releasing intrauterine system in women without previous vaginal delivery: a RCT.
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cervix Uteri; Female; Humans; In | 2014 |
A randomized trial comparing intravenous paracetamol, topical lidocaine, and ice application for treatment of pain associated with scorpion stings.
Topics: Acetaminophen; Administration, Intravenous; Administration, Topical; Adolescent; Adult; Aged; Aged, | 2015 |
Administration of subcutaneous buffered lidocaine prior to breast lymphoscintigraphy reduces pain without decreasing lymph node visualization.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Buffers; Female; Humans; Injections, Subcutaneous; | 2014 |
Effect of analgesia and anti-inflammatory treatment on weight gain and milk intake of dairy calves after disbudding.
Topics: Analgesia; Anesthetics, Local; Animal Husbandry; Animals; Anti-Inflammatory Agents, Non-Steroidal; C | 2015 |
Using the mouse grimace scale to assess pain associated with routine ear notching and the effect of analgesia in laboratory mice.
Topics: Analgesics; Animal Identification Systems; Animals; Ear; Facial Expression; Lidocaine; Lidocaine, Pr | 2015 |
Safety and effectiveness of injection of calcium hydroxylapatite via blunt cannula compared to injection by needle for correction of nasolabial folds.
Topics: Aged; Anesthetics, Local; Catheters; Contusions; Cosmetic Techniques; Durapatite; Edema; Erythema; F | 2014 |
Clinical efficacy of lidocaine, mepivacaine, and articaine for local infiltration.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Bicuspid; Carticaine; Dental Pulp; Double | 2011 |
Effect of operator and subject gender on injection pain: a randomized double-blind study.
Topics: Adult; Anesthesia, Dental; Double-Blind Method; Epinephrine; Female; Humans; Incisor; Lidocaine; Mal | 2015 |
Effect of sodium bicarbonate-buffered lidocaine on the success of inferior alveolar nerve block for teeth with symptomatic irreversible pulpitis: a prospective, randomized double-blind study.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Combined; Anesthet | 2015 |
Lidocaine-prilocaine cream as analgesia for hysterosalpingography: a randomized, double blinded, controlled study.
Topics: Adult; Analgesia; Anesthesia, Local; Anesthetics, Local; Contrast Media; Double-Blind Method; Drug C | 2014 |
Novel topical formulation of lidocaine provides significant pain relief for intrauterine device insertion: pharmacokinetic evaluation and randomized placebo-controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Chemistry, Pharmaceutical; Double-Blind Method; | 2015 |
A new protocol to evaluate the effect of topical anesthesia.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Cross-Over Studies; Double-Blind M | 2014 |
Listening to music during transrectal ultrasound-guided prostate biopsy decreases anxiety, pain and dissatisfaction in patients: a pilot randomized controlled trial.
Topics: Aged; Anxiety; Biopsy; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; Music; Pain; Pain Measu | 2015 |
A Clinical Comparison of EMLA Cream and Ethyl Chloride Spray Application for Pain Relief of Forehead Botulinum Toxin Injection.
Topics: Acetylcholine Release Inhibitors; Adult; Aerosols; Anesthetics, Local; Botulinum Toxins, Type A; Cos | 2015 |
Prospective study of a single treatment strategy for local tumescent anesthesia in Muller phlebectomy.
Topics: Adult; Aged; Analgesics; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2015 |
Opposite effects of the same drug: reversal of topical analgesia by nocebo information.
Topics: Administration, Topical; Adult; Analgesia; Anesthetics, Local; Emotions; Female; Humans; Lidocaine; | 2015 |
Pressure Makes Pleasure: A Preliminary Study of Increasing Irrigation Pressure of Flexible Cystoscopy Improves Male Patient Comfort by an Easy Way.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Cystoscopy; Gels; Humans; Lidocaine; Male; Middl | 2015 |
Lignocaine/phenylephrine nasal spray vs. placebo for the pain and distress of nasogastric tube insertion in children: a study protocol for a randomized controlled trial.
Topics: Child, Preschool; Clinical Protocols; Double-Blind Method; Drug Combinations; Humans; Infant; Intuba | 2015 |
Novel approach for pain control in patients undergoing prostate biopsy: iliohypogastric nerve block with or without topical application of prilocaine-lidocaine: a randomized controlled trial.
Topics: Administration, Rectal; Administration, Topical; Anesthesia, Local; Anesthetics, Local; Endoscopic U | 2015 |
Does Topical Anesthetic Reduce Pain During Intraosseous Pin Removal in Children? A Randomized Controlled Trial.
Topics: Administration, Topical; Anesthetics, Local; Bone Nails; Child; Child, Preschool; Device Removal; Fe | 2016 |
Alkalinized lidocaine versus lidocaine gel as local anesthesia prior to intra-vesical botulinum toxin (BoNTA) injections: A prospective, single center, randomized, double-blind, parallel group trial of efficacy and morbidity.
Topics: Aged; Anesthetics, Local; Botulinum Toxins; Double-Blind Method; Female; Gels; Humans; Injections; L | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Lidocaine 10% spray to the cervix reduces pain during intrauterine device insertion: a double-blind randomised controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Contraception; Double-Blind Method | 2016 |
Efficacy of lignocaine in gel and spray form during buccal infiltration anesthesia in children: a randomized clinical trial.
Topics: Administration, Buccal; Aerosols; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Child; | 2014 |
A randomized, evaluator-blinded, controlled study of effectiveness and safety of small particle hyaluronic acid plus lidocaine for lip augmentation and perioral rhytides.
Topics: Adolescent; Aged; Anesthetics, Local; Contusions; Cosmetic Techniques; Edema; Female; Gels; Humans; | 2015 |
Effect of needle design on pain from dental local anesthetic injections.
Topics: Adult; Aged; Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Equipment Design; Female; | 2015 |
Heparin and alkalinized lidocaine versus alkalinized lidocaine for treatment of interstitial cystitis symptoms.
Topics: Adult; Aged; Anesthetics, Local; Anticoagulants; Cystitis, Interstitial; Drug Therapy, Combination; | 2015 |
A blinded, randomized, split-face pilot study of bruising and pain with hyaluronic acid for correction of perioral lines using no lidocaine, lidocaine alone, and lidocaine and epinephrine.
Topics: Adult; Aged; Anesthetics, Local; Contusions; Cosmetic Techniques; Double-Blind Method; Epinephrine; | 2015 |
A Randomized Clinical Trial of Jet-Injected Lidocaine to Reduce Venipuncture Pain for Young Children.
Topics: Anesthetics, Local; Child; Child, Preschool; Equipment Design; Female; Humans; Infant; Injections, J | 2015 |
A Randomized Clinical Trial of Jet-Injected Lidocaine to Reduce Venipuncture Pain for Young Children.
Topics: Anesthetics, Local; Child; Child, Preschool; Equipment Design; Female; Humans; Infant; Injections, J | 2015 |
A Randomized Clinical Trial of Jet-Injected Lidocaine to Reduce Venipuncture Pain for Young Children.
Topics: Anesthetics, Local; Child; Child, Preschool; Equipment Design; Female; Humans; Infant; Injections, J | 2015 |
A Randomized Clinical Trial of Jet-Injected Lidocaine to Reduce Venipuncture Pain for Young Children.
Topics: Anesthetics, Local; Child; Child, Preschool; Equipment Design; Female; Humans; Infant; Injections, J | 2015 |
Lidocaine-Prilocaine Cream as Analgesia for IUD Insertion: A Prospective, Randomized, Controlled, Triple Blinded Study.
Topics: Adult; Analgesia; Anesthetics, Combined; Double-Blind Method; Female; Humans; Intrauterine Devices; | 2015 |
The magnitude of placebo analgesia effects depends on how they are conceptualized.
Topics: Adult; Analgesia; Anesthetics, Local; Area Under Curve; Concept Formation; Female; Healthy Volunteer | 2015 |
Combination of Tramadol and Lidocaine for Pain Control During Transrectal Ultrasound-guided Prostate Biopsy: A Randomized Double-blinded Study.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Biopsy, Needle; Double-Blind Method; Drug Therapy, Com | 2015 |
Pain on administration of non-alkalinised lidocaine for carpal tunnel decompression: A comparison between the Gale and the "advancing wheal" techniques.
Topics: Adult; Anesthetics, Local; Carpal Tunnel Syndrome; Decompression, Surgical; Female; Humans; Injectio | 2016 |
Safety and Efficacy of a Needle-free Powder Lidocaine Delivery System in Pediatric Patients Undergoing Venipuncture or Peripheral Venous Cannulation: Randomized Double-blind COMFORT-004 Trial.
Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Catheterization, Peripheral; Child; Doubl | 2015 |
Selective Low-Dose Spinal Anesthesia for Transrectal Prostate Biopsy: A Prospective and Randomized Study.
Topics: Aged; Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Local; Biopsy, Large-Core Needle; Bupivaca | 2015 |
Effect of a topical anaesthetic formulation on the cortisol response to surgical castration of unweaned beef calves.
Topics: Anesthetics, Local; Animals; Cattle; Chemistry, Pharmaceutical; Hydrocortisone; Lidocaine; Male; Orc | 2016 |
Comparison of local infiltration anesthesia and peripheral nerve block: a randomized prospective study in hand lacerations.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Female; Hand; Humans; Lacerations; L | 2015 |
Prospective evaluation of pain and follow-up results when pre-cooling skin versus buffering lidocaine for upper blepharoplasty.
Topics: Adult; Anesthetics, Local; Blepharoplasty; Buffers; Cold Temperature; Female; Humans; Lidocaine; Mal | 2015 |
Endoscopic sphenopalatine ganglion blockade efficacy in pain control after endoscopic sinus surgery.
Topics: Adult; Anesthesia, General; Drug Combinations; Endoscopy; Epinephrine; Female; Humans; Injections; L | 2016 |
The Effect of 2 Injection Speeds on Local Anesthetic Discomfort During Inferior Alveolar Nerve Blocks.
Topics: Adolescent; Adult; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female; Humans; Inje | 2015 |
The influence of injection speed on pain during injection of local anaesthetic.
Topics: Abdomen; Adult; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middl | 2016 |
Intraurethral Lidocaine for Urethral Catheterization in Children: A Randomized Controlled Trial.
Topics: Anesthetics, Local; Child, Preschool; Double-Blind Method; Female; Humans; Infant; Lidocaine; Lubric | 2015 |
Effects of pretreatment with esmolol and lidocaine on injection pain and rocuronium-induced withdrawal response.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Androstanols; Anesthesia, General; Anesthetics, Intra | 2015 |
Effect of lidocaine spray in pain management during office-based endometrial sampling: A randomised placebo-controlled trial.
Topics: Adult; Ambulatory Care; Anesthetics, Local; Biopsy; Double-Blind Method; Endometrium; Female; Humans | 2016 |
COMPARISON OF PAIN CONTROL DURING TRUS GUIDED BIOPSIES BETWEEN BASAL PERI-PROSTATIC LOCAL INFILTRATION ANESTHESIA VERSUS COMBINED TOPICAL ANAL LIGNOCAINE OINTMENT AND LOCAL INFILTRATION ANESTHESIA.
Topics: Administration, Topical; Anesthetics, Local; Biopsy; Drug Administration Routes; Humans; Lidocaine; | 2015 |
Lidocaine Skin Patch (Lidopat® 5%) Is Effective in the Treatment of Traumatic Rib Fractures: A Prospective Double-Blinded and Vehicle-Controlled Study.
Topics: Analgesics, Opioid; Anesthetics, Local; Double-Blind Method; Drug Utilization; Female; Humans; Lengt | 2016 |
Magnesium Sulfate Plus Lidocaine Reduces Propofol Injection Pain: A Double-blind, Randomized Study.
Topics: Adult; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Drug Therapy, | 2016 |
The Effect of Intrauterine Lidocaine and Rectal Indomethacin on Pain during Office Vaginoscopic Hysteroscopy: Randomized Double-Blind Controlled Study.
Topics: Adult; Ambulatory Surgical Procedures; Anesthetics, Local; Double-Blind Method; Endometrial Neoplasm | 2016 |
Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, pethidine & diclofenac sodium application for pain relief during fractional curettage: A randomized controlled trial.
Topics: Acetaminophen; Adult; Aged; Analgesia; Curettage; Diclofenac; Female; Gynecologic Surgical Procedure | 2015 |
Evaluation of a Local Anesthesia Simulation Model with Dental Students as Novice Clinicians.
Topics: Anatomic Landmarks; Anesthesia, Dental; Anesthesiology; Anesthetics, Local; Attitude of Health Perso | 2015 |
Does Topical Lidocaine Reduce the Pain Associated With the Insertion of Nasal Continuous Positive Airway Pressure Prongs in Preterm Infants?: A Randomized, Controlled Pilot Trial.
Topics: Administration, Topical; Anesthetics, Local; Continuous Positive Airway Pressure; Female; Gels; Huma | 2016 |
Comparison of pain perception during miniscrew placement in orthodontic patients with a visual analog scale survey between compound topical and needle-injected anesthetics: A crossover, prospective, randomized clinical trial.
Topics: Administration, Topical; Adolescent; Adult; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, | 2016 |
Radial artery blood gas sampling: a randomized controlled trial of lidocaine local anesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Blood Gas Analysis; Female; Humans; Lidocaine; Male; Middle A | 2015 |
Continuous Lidocaine Infusions to Manage Opioid-Refractory Pain in a Series of Cancer Patients in a Pediatric Hospital.
Topics: Adolescent; Analgesics, Opioid; Child; Drug Resistance; Female; Humans; Lidocaine; Male; Neoplasms; | 2016 |
Diclofenac plus lidocaine gel for pain relief during intrauterine device insertion. A randomized, double-blinded, placebo-controlled study.
Topics: Administration, Intravaginal; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Di | 2016 |
Evaluation of 2-Stage Injection Technique in Children.
Topics: Administration, Buccal; Adolescent; Anesthesia, Dental; Anesthetics, Local; Benzocaine; Child; Child | 2016 |
Intra-Articular Corticosteroids in Addition to Exercise for Reducing Pain Sensitivity in Knee Osteoarthritis: Exploratory Outcome from a Randomized Controlled Trial.
Topics: Adrenal Cortex Hormones; Aged; Anesthetics, Local; Exercise Therapy; Female; Humans; Injections, Int | 2016 |
Forearm ultrasound-guided nerve blocks vs landmark-based wrist blocks for hand anesthesia in healthy volunteers.
Topics: Anesthetics, Local; Double-Blind Method; Emergency Service, Hospital; Forearm; Humans; Injections; L | 2016 |
Comparison of lidocaine spray and paracervical block application for pain relief during first-trimester surgical abortion: A randomised, double-blind, placebo-controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Combined Modality Therapy; Do | 2016 |
Development and Clinical Evaluation of New Topical Anesthetic Formulations for Dental Care.
Topics: Adult; Agar; Anesthetics, Local; Dental Care; Double-Blind Method; Female; Gelatin; Humans; Injectio | 2016 |
Does Routine Midazolam Administration Prior to Nasogastric Tube Insertion in the Emergency Department Decrease Patients' Pain? (A Pilot Study).
Topics: Adult; Anesthesia; Double-Blind Method; Drug Combinations; Emergency Service, Hospital; Female; Huma | 2016 |
Relief of Injection Pain During Delivery of Local Anesthesia by Computer-Controlled Anesthetic Delivery System for Periodontal Surgery: Randomized Clinical Controlled Trial.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Drug Therapy, Computer-Assisted; Humans; | 2016 |
Tolerability of 2.5% Lidocaine/Prilocaine Hydrogel in Children Undergoing Cryotherapy for Molluscum Contagiosum.
Topics: Anesthetics, Local; Child; Child, Preschool; Cryotherapy; Drug Combinations; Drug Tolerance; Female; | 2016 |
Comparison of local anesthetic effect of lidocaine by jet injection vs needle infiltration in lumbar puncture.
Topics: Adult; Anesthetics, Local; Emergency Service, Hospital; Female; Humans; Injections, Jet; Lidocaine; | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Comparative Evaluation of Mental Incisal Nerve Block, Inferior Alveolar Nerve Block, and Their Combination on the Anesthetic Success Rate in Symptomatic Mandibular Premolars: A Randomized Double-blind Clinical Trial.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bicuspid; Double-Blind Method; Dru | 2016 |
Refining paracervical block techniques for pain control in first trimester surgical abortion: a randomized controlled noninferiority trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Labor Stage, | 2016 |
Refining paracervical block techniques for pain control in first trimester surgical abortion: a randomized controlled noninferiority trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Labor Stage, | 2016 |
Refining paracervical block techniques for pain control in first trimester surgical abortion: a randomized controlled noninferiority trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Labor Stage, | 2016 |
Refining paracervical block techniques for pain control in first trimester surgical abortion: a randomized controlled noninferiority trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Labor Stage, | 2016 |
Refining paracervical block techniques for pain control in first trimester surgical abortion: a randomized controlled noninferiority trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Labor Stage, | 2016 |
Refining paracervical block techniques for pain control in first trimester surgical abortion: a randomized controlled noninferiority trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Labor Stage, | 2016 |
Refining paracervical block techniques for pain control in first trimester surgical abortion: a randomized controlled noninferiority trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Labor Stage, | 2016 |
Refining paracervical block techniques for pain control in first trimester surgical abortion: a randomized controlled noninferiority trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Labor Stage, | 2016 |
Refining paracervical block techniques for pain control in first trimester surgical abortion: a randomized controlled noninferiority trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Labor Stage, | 2016 |
Effect of intravenous lidocaine combined with amitriptyline on pain intensity, clinical manifestations and the concentrations of IL-1, IL-6 and IL-8 in patients with fibromyalgia: A randomized double-blind study.
Topics: Administration, Intravenous; Adult; Amitriptyline; Anesthetics, Local; Biomarkers; Brazil; Double-Bl | 2016 |
The influence of Lidocaine temperature on pain during subcutaneous injection.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Double-Blind Method; Female; Humans; Injections, Subcut | 2017 |
Comparison of the effects of lidocaine pre-administration and local warming of the intravenous access site on propofol injection pain: Randomized, double-blind controlled trial.
Topics: Double-Blind Method; Fever; Humans; Lidocaine; Pain; Propofol; Prospective Studies | 2016 |
Self-Administered Lidocaine Gel for Pain Control With First-Trimester Surgical Abortion: A Randomized Controlled Trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gels; Humans; Lidocai | 2016 |
Evaluation of Buccal Infiltration with Articaine and Inferior Alveolar Nerve Block with Lignocaine for Pulp Therapy in Mandibular Primary Molars.
Topics: Anesthesia, Dental; Anesthesia, Local; Carticaine; Child; Child, Preschool; Dental Pulp; Female; Hum | 2016 |
In vitro and in vivo Evaluation of New Topical Anaesthetic Cream Formulated with Palm Oil Base.
Topics: Anesthetics, Local; Drug Combinations; Female; Healthy Volunteers; Humans; Lidocaine; Male; Pain; Pa | 2017 |
Self-Administered Lidocaine Gel for Intrauterine Device Insertion in Nulliparous Women: A Randomized Controlled Trial.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Intrauterine Devices; Lidocaine; Pai | 2016 |
Vapocoolant Spray Versus Lidocaine Infiltration for Radial Artery Cannulation: A Prospective, Randomized, Controlled Clinical Trial.
Topics: Aerosols; Aged; Anesthetics, Local; Catheterization, Peripheral; Cryoanesthesia; Female; Humans; Inj | 2017 |
A Novel Pain Alternative for Patients with Anorectal Pathologies: The Comparison of Transperineal Prostatic Blockage Technique with Periprostatic Nerve Blockage and Rectal Gel Technique in Initial Transrectal Ultrasound-Guided Prostate Biopsy - A Prospect
Topics: Anesthetics, Local; Biopsy; Humans; Lidocaine; Male; Nerve Block; Pain; Prospective Studies; Prostat | 2016 |
The Influence of Injected Volume on Discomfort During Administration of Digital Block.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Dose-Response Relationship, Drug; Female; Fingers; Heal | 2016 |
Serum concentration of ketamine and antinociceptive effects of ketamine and ketamine-lidocaine infusions in conscious dogs.
Topics: Analgesics; Anesthetics, Local; Animals; Cross-Over Studies; Dog Diseases; Dogs; Ketamine; Lidocaine | 2016 |
A Randomized Trial on the Efficacy of Topical Anesthesia for Pain Reduction during Frame Placement for Gamma Knife Radiosurgery.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Brain Diseases; Forehead; Humans; Lidocain | 2016 |
Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Dental; Anesthesia, | 2016 |
Effect of cervical lidocaine-prilocaine cream on pain perception during copper T380A intrauterine device insertion among parous women: A randomized double-blind controlled trial.
Topics: Administration, Intravaginal; Adult; Anesthetics, Combined; Anesthetics, Local; Double-Blind Method; | 2017 |
Effect of cervical lidocaine-prilocaine cream on pain perception during copper T380A intrauterine device insertion among parous women: A randomized double-blind controlled trial.
Topics: Administration, Intravaginal; Adult; Anesthetics, Combined; Anesthetics, Local; Double-Blind Method; | 2017 |
Effect of cervical lidocaine-prilocaine cream on pain perception during copper T380A intrauterine device insertion among parous women: A randomized double-blind controlled trial.
Topics: Administration, Intravaginal; Adult; Anesthetics, Combined; Anesthetics, Local; Double-Blind Method; | 2017 |
Effect of cervical lidocaine-prilocaine cream on pain perception during copper T380A intrauterine device insertion among parous women: A randomized double-blind controlled trial.
Topics: Administration, Intravaginal; Adult; Anesthetics, Combined; Anesthetics, Local; Double-Blind Method; | 2017 |
A randomised controlled trial assessing the efficacy of co-phenylcaine nasal spray in flexible transnasal pharyngolaryngoscopy.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Dr | 2017 |
Intraarterial Lidocaine for Pain Control in Uterine Artery Embolization: A Prospective, Randomized Study.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anesthetics, Local; Femal | 2017 |
Comparative study between 2 different doses of pregabalin and lidocaine on pain following propofol injection: A double-blind, randomized clinical consort study.
Topics: Adult; Analgesics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intra | 2016 |
A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Do | 2017 |
A Vibrating Cold Device to Reduce Pain in the Pediatric Emergency Department: A Randomized Clinical Trial.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Catheterization; Child; Cold Temperature; E | 2019 |
First-time success with needle procedures was higher with a warm lidocaine and tetracaine patch than an eutectic mixture of lidocaine and prilocaine cream.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Female; Hot Temperature; H | 2017 |
Comparing the effectiveness of vapocoolant spray and lidocaine/procaine cream in reducing pain of intravenous cannulation: A randomized clinical trial.
Topics: Administration, Topical; Aerosols; Anesthetics, Local; Anxiety; Catheterization, Peripheral; Child; | 2017 |
Development of a technique for continuous perineural blockade of the palmar nerves in the distal equine thoracic limb.
Topics: Anesthetics, Local; Animals; Bupivacaine; Female; Forelimb; Horses; Lidocaine; Male; Mepivacaine; Ne | 2008 |
Avoiding propofol injection pain in children: a prospective, randomized, double-blinded, placebo-controlled study.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Chemistry, Pharmaceutical; Child; Child, Preschool; Do | 2008 |
Does addition of lidocaine to medium- and long-chain triglyceride propofol emulsions significantly reduce pain on injection?
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Emulsions; Female; Humans; | 2008 |
A phase II pilot study to evaluate use of intravenous lidocaine for opioid-refractory pain in cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Cross-Over Studies; Double-B | 2009 |
Comparison of oral naproxen and intrauterine lignocaine instillation for pain relief during hysterosalpingography.
Topics: Administration, Oral; Adult; Analgesics; Anesthetics, Local; Female; Humans; Hysterosalpingography; | 2008 |
Duration of venous occlusion with lidocaine for preventing propofol induced pain.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Elective Surgical Procedur | 2008 |
Efficacy of combination intravenous lidocaine and dexamethasone on propofol injection pain: a randomized, double-blind, prospective study in adult Korean surgical patients.
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Dexamethasone; Double-Blind Method; Drug | 2008 |
Premedication to reduce discomfort during screening mammography.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen | 2008 |
The effect of topical lignocaine gel in pain relief for colposcopic assessment and biopsy: is it useful?
Topics: Administration, Intravaginal; Anesthetics, Local; Biopsy, Needle; Colposcopy; Double-Blind Method; F | 2008 |
Optimizing local anesthesia for grommet insertion: eutectic mixture of local anaesthetics versus Ametop: a randomized clinical trial.
Topics: Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; | 2008 |
[Ultrasound guided transrectal prostatic biopsy and pain. Prospective randomized study comparing lubricant gel, lidocaine gel, and anesthetic blockage of the neurovascular bundles with 1% lidocaine].
Topics: Aged; Anesthetics, Local; Biopsy; Gels; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Pain; Pai | 2008 |
A clinical comparison of topical piroxicam and EMLA cream for pain relief and inflammation in laser hair removal.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroi | 2009 |
Usefulness of subcutaneous nitrate for radial access.
Topics: Aged; Anesthetics, Local; Cardiac Catheterization; Double-Blind Method; Feasibility Studies; Female; | 2008 |
Delayed versus immediate urethral catheterization following instillation of local anaesthetic gel in men: a randomized, controlled clinical trial.
Topics: Aged; Aged, 80 and over; Analgesia; Anesthetics, Local; Drug Administration Schedule; Emergency Serv | 2008 |
Thyroid fine needle aspiration biopsy: is topical local anaesthesia beneficial?
Topics: Administration, Cutaneous; Adult; Analgesics; Anesthesia, Local; Anesthetics, Local; Biopsy, Fine-Ne | 2010 |
Melatonin improves tourniquet tolerance and enhances postoperative analgesia in patients receiving intravenous regional anesthesia.
Topics: Adjuvants, Anesthesia; Adult; Anesthetics, Local; Anti-Anxiety Agents; Double-Blind Method; Female; | 2008 |
Forced coughing versus local anesthesia and pain associated with cervical biopsy: a randomized trial.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Biopsy, Needle; Cervix Uteri; Confidence Intervals; Coug | 2008 |
Cost-effectiveness analysis of anesthetic agents during peripheral intravenous cannulation in the pediatric emergency department.
Topics: Administration, Topical; Adolescent; Anesthetics; Catheterization, Peripheral; Child; Child, Prescho | 2008 |
Interventions to reduce pain during vaccination in infancy.
Topics: Administration, Cutaneous; Anesthetics, Combined; Anesthetics, Local; Breast Feeding; Child, Prescho | 2009 |
Randomised controlled trial on the effectiveness of lidocaine gel vs tetracaine drops as the sole topical anaesthetic agent for primary pterygium surgery.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Female; Gels; Humans; Lidocaine; Male; Mid | 2009 |
Periprostatic nerve block (PNB) alone vs PNB combined with an anaesthetic-myorelaxant agent cream for prostate biopsy: a prospective, randomized double-arm study.
Topics: Aged; Anesthetics, Local; Biopsy, Needle; Drug Therapy, Combination; Epidemiologic Methods; Humans; | 2009 |
The anesthetic efficacy of diphenhydramine and the combination diphenhydramine/lidocaine for the inferior alveolar nerve block.
Topics: Adult; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Bicuspid; Cross-Over Studies; | 2008 |
Anaesthesia for arterial puncture in the emergency department: a randomized trial of subcutaneous lidocaine, ethyl chloride or nothing.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Arteries; Blood Specimen Collection; Confidence | 2008 |
Combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block for pain control during transrectal ultrasound guided prostate biopsy: a randomized, controlled trial.
Topics: Administration, Topical; Aged; Analgesia; Analysis of Variance; Biopsy, Needle; Chi-Square Distribut | 2009 |
A comparison of sub-Tenon's with peribulbar anaesthesia in patients undergoing sequential bilateral cataract surgery.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Drug Administration Schedule; Female | 2009 |
Evaluation of the efficacy of magnesium sulphate as an adjuvant to lignocaine for intravenous regional anaesthesia for upper limb surgery.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics; Anesthet | 2008 |
Use of buffered lidocaine in bone marrow biopsies: a randomized, controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Bone Marrow Examination; Buffers; Cross- | 2009 |
Use of buffered lidocaine in bone marrow biopsies: a randomized, controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Bone Marrow Examination; Buffers; Cross- | 2009 |
Use of buffered lidocaine in bone marrow biopsies: a randomized, controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Bone Marrow Examination; Buffers; Cross- | 2009 |
Use of buffered lidocaine in bone marrow biopsies: a randomized, controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Bone Marrow Examination; Buffers; Cross- | 2009 |
Heated lidocaine/tetracaine patch (Synera, Rapydan) compared with lidocaine/prilocaine cream (EMLA) for topical anaesthesia before vascular access.
Topics: Administration, Cutaneous; Adolescent; Adult; Anesthesia, Local; Anesthetics, Combined; Anesthetics, | 2009 |
Heated lidocaine/tetracaine patch (Synera, Rapydan) compared with lidocaine/prilocaine cream (EMLA) for topical anaesthesia before vascular access.
Topics: Administration, Cutaneous; Adolescent; Adult; Anesthesia, Local; Anesthetics, Combined; Anesthetics, | 2009 |
Heated lidocaine/tetracaine patch (Synera, Rapydan) compared with lidocaine/prilocaine cream (EMLA) for topical anaesthesia before vascular access.
Topics: Administration, Cutaneous; Adolescent; Adult; Anesthesia, Local; Anesthetics, Combined; Anesthetics, | 2009 |
Heated lidocaine/tetracaine patch (Synera, Rapydan) compared with lidocaine/prilocaine cream (EMLA) for topical anaesthesia before vascular access.
Topics: Administration, Cutaneous; Adolescent; Adult; Anesthesia, Local; Anesthetics, Combined; Anesthetics, | 2009 |
Comparative study of topical anaesthesia with lidocaine 2% vs levobupivacaine 0.75% in cataract surgery.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Double-Blind Met | 2009 |
Comparison of injection comfort of a new category of cohesive hyaluronic acid filler with preincorporated lidocaine and a hyaluronic acid filler alone.
Topics: Adult; Aged; Anesthetics, Local; Double-Blind Method; Female; Humans; Hyaluronic Acid; Injections, I | 2009 |
The analgesic effect of a metered-dose 8% lidocaine pump spray in posttraumatic peripheral neuropathy: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; | 2009 |
Admixture of ephedrine to offset side effects of propofol: a randomized, controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Anesthetics, Local; Blood Pres | 2009 |
Castration of horses under total intravenous anaesthesia: analgesic effects of lidocaine.
Topics: Analgesia; Anesthesia, Intravenous; Anesthetics; Anesthetics, Local; Animals; Equidae; Horse Disease | 2009 |
Intravenous lidocaine for fibromyalgia syndrome: an open trial.
Topics: Adult; Anesthetics, Local; Female; Fibromyalgia; Health Status; Humans; Infusions, Intravenous; Lido | 2009 |
Effects of intravenous sodium amobarbital vs lidocaine on pain and sensory abnormalities in patients with spinal cord injury.
Topics: Adult; Amobarbital; Anesthetics, Local; Female; Humans; Hypnotics and Sedatives; Injections, Intrave | 2009 |
Prevention of propofol pain: a comparative study.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
8% Lidocaine pump spray relieves pain associated with peripheral blood flow disorders.
Topics: Administration, Intranasal; Aged; Aged, 80 and over; Anesthetics, Local; Cross-Over Studies; Double- | 2009 |
Lidocaine 10% spray reduces pain during hysterosalpingography: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Female; Humans; Hysterosalpingography; Lidocaine; Pain | 2009 |
A split-face comparison of a new hyaluronic acid facial filler containing pre-incorporated lidocaine versus a standard hyaluronic acid facial filler in the treatment of naso-labial folds.
Topics: Anesthetics, Local; Cosmetic Techniques; Drug Combinations; Face; Female; Humans; Hyaluronic Acid; I | 2009 |
Effects of intramuscular anesthesia on the expression of primary and referred pain induced by intramuscular injection of hypertonic saline.
Topics: Adult; Anesthesia; Anesthetics, Local; Female; Humans; Injections, Intramuscular; Leg; Lidocaine; Ma | 2009 |
Paracervical compared with intracervical lidocaine for suction curettage: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthetics, Local; Autonomic Nerve Block; Cervix Uteri; Cohort Studies; D | 2009 |
Comparison of bupivacaine and lidocaine with epinephrine for digital nerve blocks.
Topics: Adult; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Combinations; Epinephrine; Female; | 2009 |
A randomized, double-blind controlled study of jet lidocaine compared to jet placebo for pain relief in children undergoing needle insertion in the emergency department.
Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Emergency Medical Serv | 2009 |
[A comparison of the effect of lidocaine or sodium bicarbonate mixed with rocuronium on withdrawal movement, mean arterial pressure and heart rate during rocuronium injection].
Topics: Adult; Androstanols; Anesthetics, Local; Blood Pressure; Female; Heart Rate; Humans; Injections, Int | 2009 |
Medial prefrontal cortex activity is predictive for hyperalgesia and pharmacological antihyperalgesia.
Topics: Adult; Anesthetics, Local; Brain; Brain Mapping; Cross-Over Studies; Double-Blind Method; Electric S | 2009 |
Is only perianal anesthesia with lidocaine-prilocaine cream sufficient to decrease the pain during transrectal ultrasound-guided prostate biopsy? A prospective randomized study.
Topics: Administration, Rectal; Aged; Anesthetics, Combined; Anesthetics, Local; Biopsy; Humans; Lidocaine; | 2009 |
Comparison of three analgesic treatment protocols for pain management during extracorporeal shock wave lithotripsy.
Topics: Adult; Analgesia; Anesthetics, Combined; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal | 2009 |
Comparison of articaine and lidocaine for infiltration anaesthesia in patients undergoing bone marrow aspiration and biopsy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Anxiety; Biopsy, | 2010 |
Efficacy and safety of combination therapy with 5% lidocaine medicated plaster and pregabalin in post-herpetic neuralgia and diabetic polyneuropathy.
Topics: Aged; Algorithms; Analgesics; Casts, Surgical; Diabetic Neuropathies; Drug Combinations; Female; gam | 2009 |
Does nebulized lidocaine reduce the pain and distress of nasogastric tube insertion in young children? A randomized, double-blind, placebo-controlled trial.
Topics: Anesthetics, Local; Child, Preschool; Double-Blind Method; Emergency Service, Hospital; Female; Huma | 2009 |
5% lidocaine medicated plaster versus pregabalin in post-herpetic neuralgia and diabetic polyneuropathy: an open-label, non-inferiority two-stage RCT study.
Topics: Aged; Algorithms; Analgesics; Casts, Surgical; Diabetic Neuropathies; Female; gamma-Aminobutyric Aci | 2009 |
Enhanced central pain processing of fibromyalgia patients is maintained by muscle afferent input: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Afferent Pathways; Analysis of Variance; Anesthetics, Local; Arm; Double-Blind Method; Female | 2009 |
Prevention of propofol-induced pain in children: combination of alfentanil and lidocaine vs alfentanil or lidocaine alone.
Topics: Alfentanil; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Child; Child, Preschoo | 2009 |
Amethocaine versus EMLA for successful intravenous cannulation in a children's emergency department: a randomised controlled study.
Topics: Administration, Topical; Adolescent; Anesthetics, Combined; Anesthetics, Local; Catheterization; Chi | 2009 |
Prolotherapy injections and eccentric loading exercises for painful Achilles tendinosis: a randomised trial.
Topics: Achilles Tendon; Adult; Amides; Anesthetics, Local; Cell Proliferation; Combined Modality Therapy; D | 2011 |
Prolotherapy injections and eccentric loading exercises for painful Achilles tendinosis: a randomised trial.
Topics: Achilles Tendon; Adult; Amides; Anesthetics, Local; Cell Proliferation; Combined Modality Therapy; D | 2011 |
Prolotherapy injections and eccentric loading exercises for painful Achilles tendinosis: a randomised trial.
Topics: Achilles Tendon; Adult; Amides; Anesthetics, Local; Cell Proliferation; Combined Modality Therapy; D | 2011 |
Prolotherapy injections and eccentric loading exercises for painful Achilles tendinosis: a randomised trial.
Topics: Achilles Tendon; Adult; Amides; Anesthetics, Local; Cell Proliferation; Combined Modality Therapy; D | 2011 |
Comparison between lidocaine-prilocaine cream (EMLA) and mepivacaine infiltration for pain relief during perineal repair after childbirth: a randomized trial.
Topics: Administration, Topical; Adult; Anesthetics, Combined; Anesthetics, Local; Delivery, Obstetric; Epis | 2009 |
A randomized clinical trial of lidocaine gel for reducing infant distress during urethral catheterization.
Topics: Administration, Topical; Anesthetics, Local; Double-Blind Method; Female; Follow-Up Studies; Humans; | 2009 |
Pregnancy at term does not alter the responses to a mechanical and an electrical stimulus after skin EMLA application.
Topics: Adult; Anesthetics, Local; Case-Control Studies; Cross-Over Studies; Double-Blind Method; Electric S | 2009 |
The effect of nitroglycerin as an adjuvant to lidocaine in intravenous regional anesthesia.
Topics: Adult; Anesthesia, Conduction; Anesthetics, Local; Double-Blind Method; Drug Therapy, Combination; F | 2009 |
The use of topical anesthesia during intravenous catheter insertion in adults: a comparison of pain scores using LMX-4 versus placebo.
Topics: Adult; Anesthetics, Local; Catheterization, Peripheral; Double-Blind Method; Emergency Service, Hosp | 2009 |
[Effects of the injection method of lidocaine on preventing injection pain during anesthesia induction by target controlled infusion with propofol].
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Female; Humans; Infusions, Intravenous; I | 2009 |
[Effects of granisetron/lidocaine combination on propofol injection-induced pain: a double-blind randomized clinical trial].
Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Female; Granisetron; Humans; Injections, Intr | 2009 |
The effect of needle bevel position on pain for subcutaneous lidocaine injection.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Female; Forearm; Humans; Injections, Subcutaneous; Lid | 2009 |
Standard versus pH-adjusted and lidocaine supplemented radiocolloid for patients undergoing sentinel-lymph-node mapping and biopsy for early breast cancer (PASSION-P trial): a double-blind, randomised controlled trial.
Topics: Adolescent; Adult; Anesthetics, Local; Breast Neoplasms; Double-Blind Method; Drug Combinations; Fem | 2009 |
Standard versus pH-adjusted and lidocaine supplemented radiocolloid for patients undergoing sentinel-lymph-node mapping and biopsy for early breast cancer (PASSION-P trial): a double-blind, randomised controlled trial.
Topics: Adolescent; Adult; Anesthetics, Local; Breast Neoplasms; Double-Blind Method; Drug Combinations; Fem | 2009 |
Standard versus pH-adjusted and lidocaine supplemented radiocolloid for patients undergoing sentinel-lymph-node mapping and biopsy for early breast cancer (PASSION-P trial): a double-blind, randomised controlled trial.
Topics: Adolescent; Adult; Anesthetics, Local; Breast Neoplasms; Double-Blind Method; Drug Combinations; Fem | 2009 |
Standard versus pH-adjusted and lidocaine supplemented radiocolloid for patients undergoing sentinel-lymph-node mapping and biopsy for early breast cancer (PASSION-P trial): a double-blind, randomised controlled trial.
Topics: Adolescent; Adult; Anesthetics, Local; Breast Neoplasms; Double-Blind Method; Drug Combinations; Fem | 2009 |
Does periprostatic block reduce pain during transrectal prostate biopsy? A randomized, placebo-controlled, double-blinded study.
Topics: Anesthetics, Local; Biopsy, Needle; Double-Blind Method; Humans; Lidocaine; Male; Nerve Block; Pain; | 2010 |
Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lens Implantat | 2009 |
Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lens Implantat | 2009 |
Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lens Implantat | 2009 |
Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lens Implantat | 2009 |
Prevention of pain on injection of propofol: a comparison of lidocaine with different doses of paracetamol.
Topics: Acetaminophen; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injecti | 2010 |
Prevention of pain on injection of propofol: a comparison of lidocaine with different doses of paracetamol.
Topics: Acetaminophen; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injecti | 2010 |
Prevention of pain on injection of propofol: a comparison of lidocaine with different doses of paracetamol.
Topics: Acetaminophen; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injecti | 2010 |
Prevention of pain on injection of propofol: a comparison of lidocaine with different doses of paracetamol.
Topics: Acetaminophen; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injecti | 2010 |
Lidocaine jelly and plain aqueous gel for urethral straight catheterization and the Q-tip test: a randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Gels; Humans; Lidocaine; Middle Aged; Pa | 2009 |
Antinociceptive, cardiopulmonary, and sedative effects of five intravenous infusion rates of lidocaine in conscious dogs.
Topics: Anesthetics, Local; Animals; Blood Pressure; Cross-Over Studies; Dogs; Dose-Response Relationship, D | 2009 |
[Prospective randomized study on the use of lidocaine local anesthesia in prostate biopsy].
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Middle Aged; Pain; P | 2009 |
The impact of topical lidocaine on pain level assessment during and after vacuum-assisted closure dressing changes: a double-blind, prospective, randomized study.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bandages; Double-Blind Method; Female; Humans; L | 2009 |
A multi-center, double-blind, randomized controlled study of the safety and effectiveness of Juvéderm injectable gel with and without lidocaine.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; Functional Laterali | 2009 |
A multi-center, double-blind, randomized controlled study of the safety and effectiveness of Juvéderm injectable gel with and without lidocaine.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; Functional Laterali | 2009 |
A multi-center, double-blind, randomized controlled study of the safety and effectiveness of Juvéderm injectable gel with and without lidocaine.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; Functional Laterali | 2009 |
A multi-center, double-blind, randomized controlled study of the safety and effectiveness of Juvéderm injectable gel with and without lidocaine.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; Functional Laterali | 2009 |
Topical and long-acting local anesthetic for prostate biopsy: a prospective randomized placebo-controlled study.
Topics: Administration, Rectal; Aged; Anesthetics, Local; Biopsy; Bupivacaine; Gels; Humans; Injections; Lid | 2009 |
Comparative efficacy of 2 topical anesthetics for the placement of orthodontic temporary anchorage devices.
Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Benzocaine; | 2009 |
Comparison of lidocaine 1% and normal saline in paracervical anesthesia for decreasing of pain in curettage.
Topics: Adolescent; Adult; Anesthetics, Local; Curettage; Double-Blind Method; Female; Humans; Iran; Lidocai | 2009 |
Fentanyl pre-treatment alleviates pain during injection of propofol-lipuro premixed with lignocaine.
Topics: Adult; Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Drug Administr | 2008 |
Comparison of ropivacaine 0.2% and 0.25% with lidocaine 0.5% for intravenous regional anesthesia.
Topics: Adult; Amides; Analgesics; Anesthesia, Conduction; Anesthetics, Local; Dose-Response Relationship, D | 2009 |
Rapid injection of rocuronium reduces withdrawal movement on injection.
Topics: Adolescent; Adult; Androstanols; Anesthetics, Intravenous; Anesthetics, Local; Female; Hospitals, Un | 2009 |
Direct evidence for spinal cord involvement in placebo analgesia.
Topics: Adult; Analgesia; Analgesics; Humans; Lidocaine; Magnetic Resonance Imaging; Male; Pain; Pain Measur | 2009 |
Lidocaine-based topical anesthetic with disinfectant (LidoDin) versus EMLA for venipuncture: a randomized controlled trial.
Topics: Adolescent; Adult; Anesthetics, Combined; Anesthetics, Local; Child; Disinfectants; Edema; Erythema; | 2009 |
A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; | 2009 |
A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; | 2009 |
A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; | 2009 |
A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; | 2009 |
Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2009 |
Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2009 |
Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2009 |
Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2009 |
Pain on injection from propofol may be avoided by changing its formulation.
Topics: Anesthetics; Anesthetics, Local; Chemistry, Pharmaceutical; Double-Blind Method; Fourier Analysis; H | 2010 |
The efficacy of a topical anesthetic gel in the relief of pain associated with localized alveolar osteitis.
Topics: Administration, Topical; Adult; Anesthetics, Combined; Anesthetics, Local; Dry Socket; Eugenol; Fema | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial.
Topics: Adult; Ambulatory Care; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Hu | 2010 |
Evaluation of mandibular infiltration versus mandibular block anaesthesia in treating primary canines in children.
Topics: Anesthesia, Dental; Anesthetics, Local; Child; Child Behavior; Cooperative Behavior; Cuspid; Dental | 2010 |
Light sensitivity and pain sensation during cataract surgery. A comparative study of two modes of anaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Cataract Extraction; Dose-Response Relationship, | 2010 |
Randomized, double-blind, placebo-controlled trial using lidocaine patch 5% in traumatic rib fractures.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Length of | 2010 |
A comparison of the local anesthetic efficacy of the extraoral versus the intraoral infraorbital nerve block.
Topics: Adult; Anesthetics, Local; Bicuspid; Cross-Over Studies; Cuspid; Dental Pulp; Dental Pulp Test; Epin | 2010 |
Transrectal ultrasound-guided prostate biopsy, periprostatic local anesthesia and pain tolerance.
Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle; Diclofenac; Human | 2010 |
[Tolerance of prostate biopsy with use of local anesthesia and benzodiazepines: a randomized, prospective study].
Topics: Administration, Topical; Adult; Aged; Anesthesia, Local; Anti-Anxiety Agents; Benactyzine; Biopsy, N | 2010 |
Lidocaine eye drops attenuate pain associated with ophthalmic postherpetic neuralgia.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Eye Diseases; | 2010 |
Addition of lidocaine suppositories to periprostatic nerve block enhances pain control in prostate biopsies: a placebo-controlled randomized trial.
Topics: Administration, Rectal; Adult; Aged; Anesthetics, Local; Austria; Biopsy, Needle; Double-Blind Metho | 2010 |
Comparison of oral nonsteroidal analgesic and intrauterine local anesthetic for pain relief in uterine fractional curettage: a randomized, double-blind, placebo-controlled trial.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Anesthesia, Local; Anesthesia, Obstetrica | 2010 |
[Topical anesthesia before vascular access in children. Comparison of a warmth-producing lidocaine-tetracaine patch with a lidocaine-prilocaine patch].
Topics: Administration, Cutaneous; Adolescent; Anesthesia, Local; Anesthetics, Local; Behavior; Child; Child | 2010 |
Does the newer preparation of propofol, an emulsion of medium/long chain triglycerides cause less injection pain in children when premixed with lignocaine?
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local; Child; Child, Presc | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
A randomized controlled trial of analgesia during vaccination in adults.
Topics: Administration, Cutaneous; Adult; Analgesia; Anesthetics, Local; Female; Humans; Hydrocarbons, Fluor | 2010 |
The effects of training time, sensory loss and pain on human motor learning.
Topics: Adult; Anesthetics, Local; Capsaicin; Feedback, Sensory; Female; Follow-Up Studies; Humans; Learning | 2010 |
Local Anesthesia with Bupivacaine and Lidocaine for Vertebral Fracture trial (LABEL): a report of outcomes and comparison with the Investigational Vertebroplasty Efficacy and Safety Trial (INVEST).
Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Fractures, Compression; Humans; | 2010 |
Efficacy of intrauterine lignocaine plus vaginal misoprostol for pain relief in premenopausal women undergoing endometrial aspiration and ambulatory hysteroscopy.
Topics: Administration, Intravaginal; Adult; Ambulatory Care; Anesthetics, Local; Biopsy, Fine-Needle; Endom | 2010 |
The efficacy of periprostatic local anaesthetic infiltration in transrectal ultrasound biopsy of prostate: a prospective randomised control study.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Biopsy; Humans; Injections; Lidocaine; Male; Pain; Pros | 2010 |
Intravenous regional anesthesia using lidocaine and neostigmine for upper limb surgery.
Topics: Adolescent; Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Combined; Anestheti | 2010 |
Safety of lidocaine 15% and prilocaine 5% topical ointment used as local anesthesia for intense pulsed light treatment.
Topics: Administration, Cutaneous; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Cosmetic Techniques; | 2010 |
Contribution of a heating element to topical anesthesia patch efficacy prior to vascular access: results from two randomized, double-blind studies.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Analgesia; Anesthetics, Local; Double-Blind Meth | 2010 |
Vapocoolant spray vs subcutaneous lidocaine injection for reducing the pain of intravenous cannulation: a randomized, controlled, clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Catheterization, Peripheral; Emergen | 2010 |
Should lidocaine spray be used to ease nasogastric tube insertion? A double-blind, randomised controlled trial.
Topics: Anesthetics, Local; Double-Blind Method; Emergency Service, Hospital; Female; Hong Kong; Humans; Int | 2010 |
The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-S | 2010 |
Effect of eutectic mixture of local anesthetics on pain perception during scaling by ultrasonic or hand instruments: a masked randomized controlled trial.
Topics: Adult; Analysis of Variance; Anesthetics, Combined; Anesthetics, Local; Dental Instruments; Drug Com | 2011 |
Lidocaine spray administration during transrectal ultrasound guided prostate biopsy modified the discomfort and pain of the procedure: results of a randomized clinical trial.
Topics: Aged; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; Nebulizers and Vapor | 2010 |
Lidocaine gel as an anesthetic protocol for nasogastric tube insertion in the ED.
Topics: Administration, Intranasal; Aged; Aged, 80 and over; Anesthetics, Local; Cellulose; Cohort Studies; | 2011 |
The effect of lidocaine when mixed with large gel particle hyaluronic acid filler tolerability and longevity: a six-month trial.
Topics: Adult; Aged; Anesthetics, Local; Biocompatible Materials; Contusions; Cosmetic Techniques; Double-Bl | 2010 |
Double-blind, randomized, intraindividual comparison study of the efficacy of prilocaine and lidocaine in tumescent local anesthesia.
Topics: Adult; Anesthesia, Local; Double-Blind Method; Female; Hip; Humans; Lidocaine; Lipectomy; Male; Midd | 2010 |
Effects of lidocaine patch on intradermal capsaicin-induced pain: a double-blind, controlled trial.
Topics: Anesthetics, Local; Capsaicin; Double-Blind Method; Humans; Hyperalgesia; Injections, Intradermal; L | 2011 |
The efficacy of infiltration anaesthesia for adult mandibular incisors: a randomised double-blind cross-over trial comparing articaine and lidocaine buccal and buccal plus lingual infiltrations.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Cross-Over Studies; De | 2010 |
Dimethyl sulfoxide with lignocaine versus eutectic mixture of local anesthetics: prospective randomized study to compare the efficacy of cutaneous anesthesia in shock wave lithotripsy.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Anesthetics, Local; Dimethyl Sulfoxide; Drug The | 2011 |
A lidocaine-containing formulation of large-gel particle hyaluronic acid alleviates pain.
Topics: Anesthetics, Local; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Face; | 2010 |
Does lidocaine more effectively prevent pain upon induction with propofol or etomidate when given preemptively than when mixed with the drug?
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Drug Administration | 2010 |
Liposomal delivery system for topical anaesthesia of the palatal mucosa.
Topics: Administration, Topical; Adult; Amides; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Loca | 2012 |
Liposomal delivery system for topical anaesthesia of the palatal mucosa.
Topics: Administration, Topical; Adult; Amides; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Loca | 2012 |
Liposomal delivery system for topical anaesthesia of the palatal mucosa.
Topics: Administration, Topical; Adult; Amides; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Loca | 2012 |
Liposomal delivery system for topical anaesthesia of the palatal mucosa.
Topics: Administration, Topical; Adult; Amides; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Loca | 2012 |
A randomised controlled trial to assess pain with urethral swabs.
Topics: Adult; Anesthetics, Local; Chlamydia Infections; Cross-Over Studies; Cystoscopy; Diagnostic Techniqu | 2011 |
Analgesic effect of supplemental intracameral lidocaine during phacoemulsification under topical anaesthesia: a randomised controlled trial.
Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Double-Blind Method; Female; Hum | 2011 |
Reducing procedural pain and discomfort associated with transcranial direct current stimulation.
Topics: Adult; Electric Stimulation Therapy; Female; Forehead; Humans; Lidocaine; Lidocaine, Prilocaine Drug | 2011 |
Efficacy of fentanyl and/or lidocaine on total antioxidants and total oxidants during craniotomy.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Antioxidants; Craniotomy; Double-Blind Method; | 2011 |
Local anesthesia before IV catheterization.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Buffers; Catheterization, Per | 2011 |
Determining the technical and clinical factors associated with pain for children undergoing botulinum toxin injections under nitrous oxide and anesthetic cream.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Botulinum Toxins, Type A; Cerebral Palsy; C | 2011 |
Efficacy of the lidocaine/flurbiprofen axetil combination for reducing pain during the injection of propofol.
Topics: Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Lo | 2011 |
Noninfiltrative anesthesia for transrectal prostate biopsy: a randomized prospective study comparing lidocaine-prilocaine cream and lidocaine-ketorolac gel.
Topics: Administration, Rectal; Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, N | 2013 |
Lidocaine spray in addition to paracervical block reduces pain during first-trimester surgical abortion: a placebo-controlled clinical trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Lidocaine; Pa | 2011 |
Effect of liposomal lidocaine and sucrose alone and in combination for venipuncture pain in newborns.
Topics: Administration, Topical; Anesthetics, Local; Combined Modality Therapy; Double-Blind Method; Female; | 2011 |
Intra-arterial lidocaine versus saline to reduce peri-procedural discomfort in patients undergoing percutaneous trans-radial or trans-ulnar coronary procedures.
Topics: Aged; Anesthetics, Local; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Coronary Disease; | 2011 |
Adjuvant use of intravenous lidocaine for procedural burn pain relief: a randomized double-blind, placebo-controlled, cross-over trial.
Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Opioid; Anxiety; Burns; Cross-Over Studies; Double-B | 2011 |
Transrectal ultrasound guided multi-core prostate biopsy: pain control: results of 106 patients.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; N | 2011 |
Piriformis syndrome: long-term follow-up in patients treated with percutaneous injection of anesthetic and corticosteroid under CT guidance.
Topics: Adult; Anesthetics; Drug Combinations; Female; Follow-Up Studies; Glucocorticoids; Humans; Injection | 2012 |
Nerve blocks at the wrist for painful injections of the palm.
Topics: Adrenal Cortex Hormones; Adult; Anesthetics, Local; Dupuytren Contracture; Female; Hand; Humans; Inj | 2011 |
EMLA versus glucose for PICC insertion: a randomised triple-masked controlled study.
Topics: Analgesia; Anesthetics, Local; Catheterization, Central Venous; Glucose; Humans; Infant, Newborn; In | 2011 |
Comparison of three concentrations of simplex lidocaine in local anesthesia for inguinal hernia mesh-repairs.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Female; Hernia, Inguinal; Her | 2011 |
Response to diagnostic injection in patients with femoroacetabular impingement, labral tears, chondral lesions, and extra-articular pathology.
Topics: Adolescent; Adult; Anesthetics, Local; Anti-Inflammatory Agents; Arthroscopy; Bupivacaine; Bursitis; | 2011 |
Pain on injection of propofol: a comparison of methylene blue and lidocaine.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Enzyme Inhibitors; Female; | 2011 |
Analgesic effects of EMLA cream and oral sucrose during venipuncture in preterm infants.
Topics: Administration, Oral; Analgesia; Anesthetics, Local; Dosage Forms; Double-Blind Method; Drug Therapy | 2011 |
Open haemorrhoidectomy under local anaesthesia for symptomatic haemorrhoids: An experience from Nigeria.
Topics: Adult; Aged; Anal Canal; Anesthesia, Local; Anesthetics, Local; Conscious Sedation; Constriction, Pa | 2011 |
Rapid local anesthesia in humans using minimally invasive microneedles.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Equipment Design; Equipment Failure Analysis; Humans | 2012 |
The effect of combined ephedrine and lidocaine pretreatment on pain and hemodynamic changes due to propofol injection.
Topics: Adult; Anesthetics, Intravenous; Ephedrine; Female; Hemodynamics; Humans; Injections; Lidocaine; Mal | 2011 |
Local anesthetic effects of Lidocaine cream: randomized controlled trial using a standardized prick pain.
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female; H | 2012 |
Comparison of topical lidocaine [2% gel] and injectable lidocaine [2% solution] for incision and curettage of chalazion in Ilorin, Nigeria.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Chalazion; | 2010 |
Efficacy of liposome-encapsulated 0.5% ropivacaine in maxillary dental anaesthesia.
Topics: Adult; Amides; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Cross-Over Studies; Dental | 2012 |
Sevoflurane to alleviate pain on propofol injection.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Fentanyl; Humans; Injections, Intr | 2011 |
No effect of perianal application of topical anaesthetic on patient comfort during nonsedated flexible sigmoidoscopy: a randomized, placebo-controlled clinical trial.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Anxiety; Female; Humans; Lidoca | 2012 |
Randomized controlled trial to compare effects of pain relief during IV insertion using bacteriostatic normal saline and 1% buffered lidocaine.
Topics: Anesthetics, Local; Double-Blind Method; Female; Humans; Infusions, Intravenous; Lidocaine; Male; Pa | 2011 |
Pain during rigid cystoscopy: a prospective randomized controlled study comparing the benefit of cooled and room temperature lignocaine gel.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cystoscopy; Gels; Humans; Lidocaine; Male; Middl | 2011 |
Lidocaine patch (5%) produces a selective, but incomplete block of Aδ and C fibers.
Topics: Adult; Aged; Anesthetics, Local; Double-Blind Method; Female; Humans; Hyperalgesia; Lidocaine; Male; | 2012 |
Combined perianal-intrarectal (PI) lidocaine-prilocaine (LP) cream and lidocaine-ketorolac gel provide better pain relief than combined PI LP cream and periprostatic nerve block during transrectal prostate biopsy.
Topics: Administration, Rectal; Aged; Anesthetics, Combined; Anesthetics, Local; Biopsy; Cyclooxygenase Inhi | 2012 |
A double-blind randomised controlled trial assessing the efficacy of topical lidocaine in extended flexible endoscopic nasal examinations.
Topics: Administration, Intranasal; Administration, Topical; Anesthetics, Local; Dose-Response Relationship, | 2011 |
Do topical anesthetics reduce periareolar injectional pain before sentinel lymph node biopsy?
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Breast Neoplasms; Double- | 2011 |
Effect of lidocaine iontophoresis on pain during needle electromyography.
Topics: Adult; Double-Blind Method; Electromyography; Female; Humans; Iontophoresis; Lidocaine; Male; Middle | 2011 |
Vapocoolant spray vs lidocaine/prilocaine cream for reducing the pain of venipuncture in hemodialysis patients: a randomized, placebo-controlled, crossover study.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Cold Temperature; Cross-Over Studies; Female; Humans; Li | 2011 |
Less painful arterial blood gas sampling using jet injection of 2% lidocaine: a randomized controlled clinical trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Blood Gas Analysis; Eme | 2012 |
Rapid injection of propofol reduces vascular pain and facilitates Laryngeal Mask Airway insertion.
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Female; Hospitals, University; Humans; La | 2011 |
Alkalinized lidocaine and heparin provide immediate relief of pain and urgency in patients with interstitial cystitis.
Topics: Administration, Intravesical; Cross-Over Studies; Cystitis, Interstitial; Double-Blind Method; Drug | 2012 |
Alkalinized lidocaine and heparin provide immediate relief of pain and urgency in patients with interstitial cystitis.
Topics: Administration, Intravesical; Cross-Over Studies; Cystitis, Interstitial; Double-Blind Method; Drug | 2012 |
Alkalinized lidocaine and heparin provide immediate relief of pain and urgency in patients with interstitial cystitis.
Topics: Administration, Intravesical; Cross-Over Studies; Cystitis, Interstitial; Double-Blind Method; Drug | 2012 |
Alkalinized lidocaine and heparin provide immediate relief of pain and urgency in patients with interstitial cystitis.
Topics: Administration, Intravesical; Cross-Over Studies; Cystitis, Interstitial; Double-Blind Method; Drug | 2012 |
A randomized controlled crossover trial: lidocaine injected at a 90-degree angle causes less pain than lidocaine injected at a 45-degree angle.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Child; Cross-Over Studies; Female; Humans; Injections; | 2011 |
Male flexible cystoscopy: does waiting after insertion of topical anaesthetic lubricant improve patient comfort?
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Chlorhexidine; Cystosco | 2011 |
Effect of intradermal anaesthesia on success rate and pain of intravenous cannulation: a randomized non-blind crossover study.
Topics: Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Cross-Over St | 2011 |
A double blind, randomised placebo controlled trial of topical 2% viscous lidocaine in improving oral intake in children with painful infectious mouth conditions.
Topics: Administration, Topical; Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Eating; F | 2011 |
Incidence of propofol injection pain and effect of lidocaine pretreatment during upper gastrointestinal endoscopy.
Topics: Aged; Anesthetics, Intravenous; Conscious Sedation; Endoscopy, Gastrointestinal; Female; Humans; Inc | 2012 |
Pain assessment of the intratympanic injections: a prospective comparative study.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents; Female | 2012 |
Equal volumes of undiluted nalbuphine and lidocaine and normal diluted saline prevents nalbuphine-induced injection pain.
Topics: Adult; Female; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Lidocaine; Male; Middle | 2011 |
A comparison of Rapydan® patch and Ametop® gel for venous cannulation.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Combined; Anesth | 2012 |
[Clean vesical intermittent catheterization: lubrication of vesical catheter through lidocaine or gentamicine?].
Topics: Antibiotic Prophylaxis; Asymptomatic Diseases; Bacteriuria; Catheter-Related Infections; Enterobacte | 2012 |
Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Gels; | 2012 |
Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Gels; | 2012 |
Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Gels; | 2012 |
Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Gels; | 2012 |
Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Gels; | 2012 |
Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Gels; | 2012 |
Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Gels; | 2012 |
Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Gels; | 2012 |
Intracervical lidocaine gel for intrauterine device insertion: a randomized controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Gels; | 2012 |
The effect of SonoPrep® on EMLA® cream application for pain relief prior to intravenous cannulation.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Double-Blind Method; Femal | 2012 |
Can ephedrine pretreatment be effective in alleviating rocuronium injection pain?
Topics: Adult; Androstanols; Anesthetics, Local; Double-Blind Method; Ephedrine; Female; Humans; Injections, | 2012 |
Availability of a 5% lidocaine patch used prophylactically for venipuncture- or injection-related pain in children.
Topics: Administration, Cutaneous; Adolescent; Androstanols; Anesthetics, Local; Child; Child, Preschool; Do | 2012 |
A comparison of the pain perceived during intravenous catheter insertion after injection with various local anesthetics.
Topics: Adult; Anesthetics, Local; Buffers; Bupivacaine; Catheterization, Peripheral; Double-Blind Method; F | 2011 |
Transpapillary versus palatal injection technique for maxillary tooth extractions.
Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Child; Dental Pa | 2012 |
An assessment of the impact of rumenocentesis on pain and stress in cattle and the effect of local anaesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Behavior, Animal; Cattle; Cattle Diseases; Female; H | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Female; Gestational Age; Huma | 2012 |
Reduction of pain on injection of propofol: combination of nitroglycerin and lidocaine.
Topics: Adult; Anesthetics, Intravenous; Double-Blind Method; Elective Surgical Procedures; Female; Humans; | 2012 |
Pain ratings by patients and their providers of radionucleotide injection for breast cancer lymphatic mapping.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Cohort Studies; Female; Humans; Injections; Lidoca | 2012 |
Randomized clinical trial of two anesthetic techniques for intravitreal injections: 4% liquid lidocaine on cotton swabs versus 3.5% lidocaine gel.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Gels; Humans; I | 2012 |
Topical EMLA for pain control during extracorporeal shock wave lithotripsy: prospective, comparative, randomized, double-blind study.
Topics: Adult; Aged; Anesthetics, Combined; Body Mass Index; Double-Blind Method; Female; Humans; Lidocaine; | 2012 |
Pain and discomfort during flexible nasolaryngoscopy: a randomized, controlled trial assessing the efficacy of oral mouthwash and topical lidocaine.
Topics: Administration, Topical; Anesthetics, Local; Drug Combinations; Drug Therapy, Combination; Female; F | 2012 |
Effects of midazolam and nitrous oxide on endocrine and metabolic measurements in children.
Topics: Adolescent; Anesthetics, Local; Blood Glucose; Blood Specimen Collection; Catheterization, Periphera | 2012 |
Perioperative intravenous lidocaine decreases the incidence of persistent pain after breast surgery.
Topics: Administration, Intravenous; Adult; Aged; Anesthetics, Local; Back Pain; Breast Neoplasms; Chronic D | 2012 |
Needle-free jet injection of lidocaine for local anesthesia during lumbar puncture: a randomized controlled trial.
Topics: Anesthesia, Local; Double-Blind Method; Female; Humans; Infant; Injections, Jet; Lidocaine; Male; Ne | 2012 |
Needle-free jet injection of lidocaine for local anesthesia during lumbar puncture: a randomized controlled trial.
Topics: Anesthesia, Local; Double-Blind Method; Female; Humans; Infant; Injections, Jet; Lidocaine; Male; Ne | 2012 |
Needle-free jet injection of lidocaine for local anesthesia during lumbar puncture: a randomized controlled trial.
Topics: Anesthesia, Local; Double-Blind Method; Female; Humans; Infant; Injections, Jet; Lidocaine; Male; Ne | 2012 |
Needle-free jet injection of lidocaine for local anesthesia during lumbar puncture: a randomized controlled trial.
Topics: Anesthesia, Local; Double-Blind Method; Female; Humans; Infant; Injections, Jet; Lidocaine; Male; Ne | 2012 |
Prevention of pain on injection of rocuronium: a comparison of lidocaine with different doses of parecoxib.
Topics: Academic Medical Centers; Adult; Androstanols; Anesthetics, Local; Cyclooxygenase 2 Inhibitors; Dose | 2012 |
A randomized, controlled trial to evaluate topical anesthetic for 15 minutes before venipuncture in pediatrics.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Double-Blind Metho | 2013 |
Lidocaine/tetracaine patch (Rapydan) for topical anaesthesia before arterial access: a double-blind, randomized trial.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetic | 2012 |
Prospective comparison between buffered 1% lidocaine-epinephrine and skin cooling in reducing the pain of local anesthetic infiltration.
Topics: Anesthetics, Local; Buffers; Cryotherapy; Drug Combinations; Epinephrine; Humans; Hydrogen-Ion Conce | 2012 |
Effect of epidural tramadol and lignocaine on physiological and behavioural changes in goats subjected to castration with a high tension band.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Hydrocortiso | 2012 |
Pain relief during hysterosalpingography: role of intracervical block.
Topics: Adult; Analgesia; Analgesics; Anesthetics, Local; Cervix Uteri; Fallopian Tube Patency Tests; Female | 2013 |
Prevention of propofol injection pain in children: a comparison of pretreatment with tramadol and propofol-lidocaine mixture.
Topics: Anesthetics, Local; Child; Female; Humans; Injections, Intravenous; Lidocaine; Male; Pain; Propofol; | 2012 |
Effect of lidocaine gel on pain from copper IUD insertion: a randomized double-blind controlled trial.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Gels; Humans; Intrauterine Devices, Copper; | 2010 |
The effect of EMLA cream on minimizing pain during venipuncture in premature infants.
Topics: Administration, Topical; Anesthetics, Local; Female; Humans; Infant, Newborn; Infant, Premature; Lid | 2013 |
No beneficial effect of intrathecal methylprednisolone acetate in postherpetic neuralgia patients.
Topics: Aged; Aged, 80 and over; Cytokines; Female; Follow-Up Studies; Humans; Lidocaine; Male; Methylpredni | 2013 |
Efficacy of epidural lidocaine combined with tramadol or neostigmine on perineal analgesia in the horse.
Topics: Analgesia; Analgesics, Opioid; Anesthetics, Local; Animals; Cross-Over Studies; Drug Therapy, Combin | 2013 |
Evaluation of inflammatory and hemostatic surgical stress responses in male cats after castration under general anesthesia with or without local anesthesia.
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Animals; Cats; I | 2012 |
Cervical lidocaine for IUD insertional pain: a randomized controlled trial.
Topics: Administration, Intravaginal; Adolescent; Adult; Anesthetics, Local; Female; Humans; Intrauterine De | 2012 |
Cervical lidocaine for IUD insertional pain: a randomized controlled trial.
Topics: Administration, Intravaginal; Adolescent; Adult; Anesthetics, Local; Female; Humans; Intrauterine De | 2012 |
Cervical lidocaine for IUD insertional pain: a randomized controlled trial.
Topics: Administration, Intravaginal; Adolescent; Adult; Anesthetics, Local; Female; Humans; Intrauterine De | 2012 |
Cervical lidocaine for IUD insertional pain: a randomized controlled trial.
Topics: Administration, Intravaginal; Adolescent; Adult; Anesthetics, Local; Female; Humans; Intrauterine De | 2012 |
Cervical lidocaine for IUD insertional pain: a randomized controlled trial.
Topics: Administration, Intravaginal; Adolescent; Adult; Anesthetics, Local; Female; Humans; Intrauterine De | 2012 |
Cervical lidocaine for IUD insertional pain: a randomized controlled trial.
Topics: Administration, Intravaginal; Adolescent; Adult; Anesthetics, Local; Female; Humans; Intrauterine De | 2012 |
Cervical lidocaine for IUD insertional pain: a randomized controlled trial.
Topics: Administration, Intravaginal; Adolescent; Adult; Anesthetics, Local; Female; Humans; Intrauterine De | 2012 |
Cervical lidocaine for IUD insertional pain: a randomized controlled trial.
Topics: Administration, Intravaginal; Adolescent; Adult; Anesthetics, Local; Female; Humans; Intrauterine De | 2012 |
Cervical lidocaine for IUD insertional pain: a randomized controlled trial.
Topics: Administration, Intravaginal; Adolescent; Adult; Anesthetics, Local; Female; Humans; Intrauterine De | 2012 |
Virtually painless local anesthesia: diluted lidocaine proves to be superior to buffered lidocaine for subcutaneous infiltration.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Buffers; Double-Blind Method; | 2012 |
Treatment of benign pigmented lesions using a long-pulse alexandrite laser.
Topics: Anesthetics, Local; Female; Follow-Up Studies; Humans; Lasers, Solid-State; Lidocaine; Middle Aged; | 2012 |
Bacteriostatic normal saline compared with buffered 1% lidocaine when injected intradermally as a local anesthetic to reduce pain during intravenous catheter insertion.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Bacterial Agents; Catheterizati | 2012 |
Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial.
Topics: Adult; Anesthetics, Intravenous; Bradycardia; Double-Blind Method; Ephedrine; Female; Humans; Hypote | 2012 |
Randomized clinical trial comparing effectiveness of intracorpus spongiosum block versus topical anesthesia for performing visual internal urethrotomy for urethral stricture disease.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Blood Pressure; Heart Rate; Humans; Intraoperative Com | 2013 |
A prospective, randomized, double-blind study to compare the efficacy of lidocaine + metoclopramide and lidocaine + ketamine combinations in preventing pain on propofol injection.
Topics: Adult; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Loca | 2013 |
Comparison of the effects of vapocoolant spray and topical anesthetic cream on pain during needle electromyography in the medial gastrocnemius.
Topics: Adult; Aged; Analysis of Variance; Anesthesia, Local; Anesthetics, Local; Confidence Intervals; Cryo | 2013 |
The effects of remifentanil, lidocaine, metoclopramide, or ketamine pretreatment on propofol injection pain.
Topics: Adult; Aged; Analgesics; Double-Blind Method; Female; Humans; Injections, Intravenous; Ketamine; Lid | 2012 |
Epidural methadone results in dose-dependent analgesia in cancer pain, further enhanced by epidural dexamethasone.
Topics: Adult; Aged; Analgesia, Epidural; Dexamethasone; Drug Administration Routes; Female; Humans; Lidocai | 2013 |
Effectiveness of two flavored topical anesthetic agents in reducing injection pain in children: a comparative study.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Child; | 2012 |
Lidocaine analgesia for removal of wound vacuum-assisted closure dressings: a randomized double-blinded placebo-controlled trial.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Cross-Over Studies; Device Removal; | 2013 |
Comparison of the effect of intratesticular lidocaine/bupivacaine vs. saline placebo on pain scores and incision site reactions in dogs undergoing routine castration.
Topics: Anesthetics, Local; Animals; Bupivacaine; Dogs; Drug Administration Routes; Drug Therapy, Combinatio | 2013 |
Comparing lidocaine, bupivacaine and a lidocaine-bupivacaine mixture as a metacarpal block in sheep.
Topics: Anesthetics, Local; Animals; Area Under Curve; Bupivacaine; Drug Therapy, Combination; Lidocaine; Me | 2013 |
A comparative evaluation of local application of the combination of eutectic mixture of local anesthetics and capsaicin for attenuation of venipuncture pain.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Capsaicin; Double-Blind Method; Drug | 2013 |
Optimizing local anesthesia during 10-core biopsy of the prostate.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Pain; Pain Mea | 2002 |
Use of lidocaine-prilocaine patch to decrease intramuscular injection pain does not adversely affect the antibody response to diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b conjugate and hepatitis B vaccines in
Topics: Administration, Topical; Anesthetics, Local; Antibody Formation; Diphtheria-Tetanus-acellular Pertus | 2002 |
Comparison of intravenous cannulation injectable preanesthetics in an adult medical inpatient population.
Topics: Anesthetics, Local; Catheterization, Peripheral; Humans; Injections, Subcutaneous; Inpatients; Lidoc | 2002 |
Periprostatic nerve block gives better analgesia for prostatic biopsy.
Topics: Aged; Aged, 80 and over; Analgesia; Anesthetics, Local; Biopsy; Gels; Humans; Lidocaine; Male; Middl | 2002 |
Effects of local anaesthesia or local anaesthesia plus a non-steroidal anti-inflammatory drug on the acute cortisol response of calves to five different methods of castration.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cattle; Hydrocort | 2002 |
Comparison of effects of lidocaine hydrochloride, buffered lidocaine, diphenhydramine, and normal saline after intradermal injection.
Topics: Adult; Analysis of Variance; Anesthetics, Local; Diphenhydramine; Double-Blind Method; Female; Hand; | 2002 |
Lack of effect of intrarectal lidocaine for pain control during transrectal prostate biopsy: a randomized prospective study.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Biopsy, Needle; Double-Blind Method; Humans; Injections | 2002 |
Magnesium Bier's block for treatment of chronic limb pain: a randomised, double-blind, cross-over study.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anesthetics, Local; Autonomic Nerve Block; Chronic Disea | 2002 |
Laser assisted delivery of topical anesthesia for intramuscular needle insertion in adults.
Topics: Adult; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Feasibility Studies; Female; Fol | 2002 |
Laser assisted delivery of topical anesthesia for intramuscular needle insertion in adults.
Topics: Adult; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Feasibility Studies; Female; Fol | 2002 |
Laser assisted delivery of topical anesthesia for intramuscular needle insertion in adults.
Topics: Adult; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Feasibility Studies; Female; Fol | 2002 |
Laser assisted delivery of topical anesthesia for intramuscular needle insertion in adults.
Topics: Adult; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Feasibility Studies; Female; Fol | 2002 |
Topical anesthetics for intravenous insertion in children: a randomized equivalency study.
Topics: Adolescent; Age Factors; Anesthetics, Local; Child; Female; Humans; Infusions, Intravenous; Injectio | 2002 |
The targeting accuracy of subacromial injection to the shoulder: an arthrographic evaluation.
Topics: Aged; Aged, 80 and over; Arthrography; Betamethasone; Contrast Media; Female; Humans; Injections, In | 2002 |
Subcutaneous lidocaine delivered by jet-injector for pain control before IV catheterization in the ED: the patients' perception and preference.
Topics: Adolescent; Adult; Aged; Catheterization, Peripheral; Drug Delivery Systems; Emergency Medical Servi | 2002 |
[Effects of concentration and dosage of lidocaine on preventing the pain on injection of propofol].
Topics: Adult; Aged; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Injections, Intrav | 2002 |
A comparison of metoclopramide and lidocaine for preventing pain on injection of diazepam.
Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthetics, Local; Diazepam; Double-Blind Method; Female; Human | 2002 |
Plasma lidocaine concentrations after local anesthesia of the groin for cardiac catheterization.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Cardiac Catheterization; Cross-Over Studies; Dos | 2002 |
Effect of topical morphine for mucositis-associated pain following concomitant chemoradiotherapy for head and neck carcinoma.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Ant | 2002 |
Transcervical intrauterine topical local anesthetic at hysterosalpingography: a prospective, randomized, double-blind, placebo-controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Human | 2002 |
Transcervical intrauterine topical local anesthetic at hysterosalpingography: a prospective, randomized, double-blind, placebo-controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Human | 2002 |
Transcervical intrauterine topical local anesthetic at hysterosalpingography: a prospective, randomized, double-blind, placebo-controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Human | 2002 |
Transcervical intrauterine topical local anesthetic at hysterosalpingography: a prospective, randomized, double-blind, placebo-controlled trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Human | 2002 |
EMLA cream and intraperitoneal lidocaine decrease intraoperative pain during postpartum tubal sterilization.
Topics: Adult; Anesthetics, Local; Chi-Square Distribution; Double-Blind Method; Female; Humans; Injections, | 2002 |
Can lidocaine reduce succinylcholine induced postoperative myalgia?
Topics: Adolescent; Adult; Aged; Analysis of Variance; Androstanols; Anesthetics, Local; Chi-Square Distribu | 2002 |
Pain reduction at venipuncture in newborns: oral glucose compared with local anesthetic cream.
Topics: Administration, Oral; Anesthesia, Local; Double-Blind Method; Glucose; Humans; Infant, Newborn; Lido | 2002 |
Evaluation of a novel topical anesthetic agent for cutaneous laser resurfacing: a randomized comparison study.
Topics: Anesthesia, Local; Anesthetics, Local; Dermatologic Surgical Procedures; Double-Blind Method; Drug C | 2002 |
Does pericapsular lignocaine reduce pain during transrectal ultrasonography-guided biopsy of the prostate?
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Biopsy, Needle; Double-Blind Method; Humans; Injections | 2002 |
Randomized trial of lidocaine ointment versus placebo for the treatment of postpartum perineal pain.
Topics: Administration, Topical; Adult; Analysis of Variance; Anesthetics, Local; Double-Blind Method; Episi | 2002 |
In children, nitrous oxide decreases pain on injection of propofol mixed with lidocaine.
Topics: Anesthetics, Intravenous; Child; Child, Preschool; Double-Blind Method; Female; Humans; Injections, | 2002 |
Pain and distress from bone marrow aspirations and lumbar punctures.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local; Biopsy, Needle; Bon | 2003 |
Lidocaine 2% gel versus lidocaine 4% unpreserved drops for topical anesthesia in cataract surgery: a randomized controlled trial.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Aqueous Humor; Double-Blind Method; Female; Gels; Human | 2003 |
Botulinum toxin-A therapy for palmar and plantar hyperhidrosis.
Topics: Adolescent; Adult; Anesthetics, Local; Botulinum Toxins, Type A; Female; Foot; Hand; Humans; Hyperhi | 2002 |
Efficacy of lignocaine 2% gel in chalazion surgery.
Topics: Adult; Anesthetics, Local; Chalazion; Eyelids; Fear; Female; Gels; Humans; Injections; Lidocaine; Ma | 2003 |
Prospective study on incidence and functional impact of transient neurologic symptoms associated with 1% versus 5% hyperbaric lidocaine in short urologic procedures.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, | 2003 |
Is instillation of anesthetic gel necessary in flexible cystoscopic examination? A prospective randomized study.
Topics: Administration, Intravesical; Anesthetics, Local; Cystoscopy; Gels; Humans; Lidocaine; Lubrication; | 2003 |
Lignocaine gel: does it cause urethral pain rather than prevent it?
Topics: Anesthetics, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Pain; Pain Measu | 2003 |
Comparison of four strategies to reduce the pain associated with intravenous administration of rocuronium.
Topics: Adjuvants, Anesthesia; Androstanols; Anesthetics, Intravenous; Anesthetics, Local; Female; Fentanyl; | 2003 |
Evaluation of eutectic lidocaine/prilocaine cream (EMLA) for steroid joint injection in children with juvenile rheumatoid arthritis: a double blind, randomized, placebo controlled trial.
Topics: Adolescent; Anesthetics, Local; Anti-Inflammatory Agents; Arthritis, Juvenile; Child; Double-Blind M | 2003 |
Nitrous oxide/oxygen mixture and the prevention of pain during injection of propofol.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analysis of Variance; Anesthetics, Intravenous; A | 2003 |
Prevention of propofol-induced injection pain by remifentanil: a placebo-controlled comparison with lidocaine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetic | 2003 |
Pain relief using paracervical block in patients undergoing manual vacuum aspiration of uterus.
Topics: Abortion, Incomplete; Adolescent; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Cervix Uteri; | 2002 |
Periprostatic administration of local anesthesia during transrectal ultrasound-guided biopsy of the prostate: a randomized, double-blind, placebo-controlled study.
Topics: Aged; Anesthetics, Local; Biopsy, Needle; Double-Blind Method; Humans; Lidocaine; Male; Middle Aged; | 2003 |
Effective reduction of anxiety and pain during venous cannulation in children: a comparison of analgesic efficacy conferred by nitrous oxide, EMLA and combination.
Topics: Adolescent; Analysis of Variance; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Local | 2003 |
Periprostatic local anesthesia eliminates pain of office-based transrectal prostate biopsy.
Topics: Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Endosonography; Humans; Lidocaine; Male; Nerv | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Local anesthetic reduces the pain of colposcopic biopsies: a randomized trial.
Topics: Adult; Anesthetics, Local; Biopsy; Cervix Uteri; Colposcopy; Curettage; Female; Humans; Injections; | 2003 |
Analgesia during radial artery cannulation: comparison of the effects of lidocaine applied by local injection or iontophoresis.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Anesthetics, Local; Catheterization, P | 2003 |
Lidocaine iontophoresis for local anesthesia before shave biopsy.
Topics: Administration, Topical; Adult; Anesthetics, Local; Biopsy; Double-Blind Method; Female; Humans; Ion | 2003 |
Pain on injection of propofol: comparison of metoprolol with lidocaine.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Hum | 2003 |
EMLA does not permit pain-free retrobulbar injection.
Topics: Administration, Topical; Anesthesia, Spinal; Anesthetics, Local; Cataract Extraction; Double-Blind M | 2003 |
Minimum clinically significant VAS differences for simultaneous (paired) interval serial pain assessments.
Topics: Administration, Topical; Adult; Anesthetics, Local; Bites and Stings; Catheterization, Peripheral; C | 2003 |
Intrapocket anesthesia for scaling and root planing in pain-sensitive patients.
Topics: Adult; Aged; Anesthesia, Dental; Anesthetics, Local; Dental Scaling; Double-Blind Method; Female; Fo | 2003 |
EMLA cream and oral glucose for immunization pain in 3-month-old infants.
Topics: Administration, Oral; Administration, Topical; Analysis of Variance; Chi-Square Distribution; Double | 2003 |
Pain during awake nasal intubation after topical cocaine or phenylephrine/lidocaine spray.
Topics: Administration, Intranasal; Adult; Aerosols; Anesthesia, Local; Anesthetics, Combined; Anesthetics, | 2003 |
Comparison of lidocaine 2% gel versus amethocaine as the sole anesthetic agent for strabismus surgery.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Female; Gels; Humans; Lidocaine; | 2003 |
The effect of mixing lidocaine with propofol on the dose of propofol required for induction of anesthesia.
Topics: Adolescent; Adult; Anesthesia, General; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics | 2003 |
The prevention of pain from injection of rocuronium by magnesium sulphate, lignocaine, sodium bicarbonate and alfentanil.
Topics: Adult; Alfentanil; Analgesics; Androstanols; Anesthetics, Local; Double-Blind Method; Female; Humans | 2003 |
Periprostatic nerve blockade before transrectal ultrasound-guided prostate biopsy: the Ankara Numune experience.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; N | 2003 |
Injection pain: comparison of three mandibular block techniques and modulation by nitrous oxide:oxygen.
Topics: Adolescent; Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Inhalation; Anesthetics, L | 2003 |
The efficacy of 5% lidocaine-prilocaine (EMLA) cream on pain during intravenous injection of propofol.
Topics: Administration, Topical; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthetics, Combi | 2003 |
Using a topical anaesthetic cream to reduce pain during sharp debridement of chronic leg ulcers.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Chronic Disease; Debr | 2001 |
Influence of site preparation methods on the pain reported during palatal infiltration using the Wand Local Anesthetic System.
Topics: Administration, Topical; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Benzocain | 2003 |
Thirty-minute application of the S-Caine peel prior to nonablative laser treatment.
Topics: Administration, Topical; Anesthetics, Local; Double-Blind Method; Drug Combinations; Female; Humans; | 2003 |
Two randomized, double-blind, placebo-controlled studies evaluating the S-Caine Peel for induction of local anesthesia before long-pulsed Nd:YAG laser therapy for leg veins.
Topics: Administration, Topical; Adult; Anesthetics, Local; Double-Blind Method; Drug Combinations; Humans; | 2003 |
The contributions of suggestion, desire, and expectation to placebo effects in irritable bowel syndrome patients. An empirical investigation.
Topics: Administration, Oral; Administration, Rectal; Adult; Anesthetics, Local; Attitude to Health; Cathete | 2003 |
Contact versus peribulbar anaesthesia in trabeculectomy: a prospective randomized clinical study.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Female; Gelatin Sponge, Absorbable; Humans | 2003 |
Statistical process control methods allow the analysis and improvement of anesthesia care.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Catheterization, Peripheral | 2003 |
Piroxicam gel, compared to EMLA cream is associated with less pain after venous cannulation in volunteers.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Catheterization, Peripheral | 2003 |
A comparison of injection pain and postoperative pain of two intraosseous anesthetic techniques.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Equipment Design; Female; Humans; | 2003 |
Full-face laser resurfacing using a supplemented topical anesthesia protocol.
Topics: Acne Vulgaris; Administration, Topical; Anesthetics, Local; Cicatrix; Face; Female; Follow-Up Studie | 2003 |
Laser-assisted penetration of topical anesthetic in adults.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Combined Modality Therapy; Dou | 2003 |
Laser-assisted penetration of topical anesthetic in adults.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Combined Modality Therapy; Dou | 2003 |
Laser-assisted penetration of topical anesthetic in adults.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Combined Modality Therapy; Dou | 2003 |
Laser-assisted penetration of topical anesthetic in adults.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Combined Modality Therapy; Dou | 2003 |
Efficacy of lidocaine patch 5% in the treatment of focal peripheral neuropathic pain syndromes: a randomized, double-blind, placebo-controlled study.
Topics: Administration, Topical; Aged; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female; | 2003 |
A randomized trial of eutectic mixture of local anesthetics during lumbar puncture in newborns.
Topics: Anesthetics, Combined; Anesthetics, Local; Chi-Square Distribution; Double-Blind Method; Humans; Inf | 2003 |
A randomized trial of eutectic mixture of local anesthetics during lumbar puncture in newborns.
Topics: Anesthetics, Combined; Anesthetics, Local; Chi-Square Distribution; Double-Blind Method; Humans; Inf | 2003 |
A randomized trial of eutectic mixture of local anesthetics during lumbar puncture in newborns.
Topics: Anesthetics, Combined; Anesthetics, Local; Chi-Square Distribution; Double-Blind Method; Humans; Inf | 2003 |
A randomized trial of eutectic mixture of local anesthetics during lumbar puncture in newborns.
Topics: Anesthetics, Combined; Anesthetics, Local; Chi-Square Distribution; Double-Blind Method; Humans; Inf | 2003 |
Pretreatment with intravenous ketamine reduces propofol injection pain.
Topics: Adolescent; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Child; Child, Preschool; Doubl | 2003 |
[Peribulbar anesthesia: comparing 1% ropivacaine and a mixture of 0.5% bupivacaine--2% lidocaine].
Topics: Aged; Amides; Anesthetics, Combined; Anesthetics, Local; Arrhythmias, Cardiac; Bupivacaine; Cataract | 2003 |
The optimum doses of and injection locations for periprostatic nerve blockade for transrectal ultrasound guided biopsy of the prostate: a prospective, randomized, placebo controlled study.
Topics: Aged; Anesthetics, Local; Biopsy, Needle; Humans; Injections; Lidocaine; Male; Middle Aged; Nerve Bl | 2003 |
Is using lignocaine gel prior to flexible cystoscopy justified? A randomized prospective study.
Topics: Anesthetics, Local; Cystoscopy; Gels; Humans; Lidocaine; Male; Middle Aged; Pain; Pain Measurement; | 2003 |
Transrectal periprostatic lidocaine injection anesthesia for transrectal prostate biopsy: a prospective study.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Biopsy; Case-Control Studies; Humans; Lidocaine; Male; M | 2003 |
Randomised comparison of distension media for outpatient hysteroscopy.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthetics, Local; Carbon Dioxide; Dilatation; Fem | 2004 |
Pain during transrectal ultrasonography guided prostate biopsy: a randomized prospective trial comparing periprostatic infiltration with lidocaine with the intrarectal instillation of lidocaine-prilocain cream.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Biopsy; Dosag | 2004 |
Assessment of pain during venous puncture using a visual analog scale and problems associated with prolonged attachment of the lidocaine patch (PENLES).
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Anesthetics, Local; Female; Humans; Injections, | 2004 |
Imaging in prostate cancer--a reply.
Topics: Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Pain; Prostate; Ultrasonography, Interv | 2004 |
[Propofol-LCT versus propofol-MCT/LCT with or without lidocaine - a comparison on pain on injection].
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; E | 2004 |
Systemic lidocaine in pain due to peripheral nerve injury and predictors of response.
Topics: Adult; Aged; Analgesics; Cold Temperature; Cross-Over Studies; Double-Blind Method; Female; Hot Temp | 2004 |
Systemic lidocaine in pain due to peripheral nerve injury and predictors of response.
Topics: Adult; Aged; Analgesics; Cold Temperature; Cross-Over Studies; Double-Blind Method; Female; Hot Temp | 2004 |
Systemic lidocaine in pain due to peripheral nerve injury and predictors of response.
Topics: Adult; Aged; Analgesics; Cold Temperature; Cross-Over Studies; Double-Blind Method; Female; Hot Temp | 2004 |
Systemic lidocaine in pain due to peripheral nerve injury and predictors of response.
Topics: Adult; Aged; Analgesics; Cold Temperature; Cross-Over Studies; Double-Blind Method; Female; Hot Temp | 2004 |
Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain.
Topics: Acetates; Activities of Daily Living; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Loca | 2003 |
Vein pretreatment with magnesium sulfate to prevent pain on injection of propofol is not justified.
Topics: Adolescent; Adult; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Elective Surgical Proce | 2004 |
A comparison of three sub-Tenon's cannulae.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Cataract Extraction; Catheter | 2004 |
Injection pain and postinjection pain of the palatal-anterior superior alveolar injection, administered with the Wand Plus system, comparing 2% lidocaine with 1:100,000 epinephrine to 3% mepivacaine.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Epinephrine; | 2004 |
Lidocaine patch 5% improves pain, stiffness, and physical function in osteoarthritis pain patients. A prospective, multicenter, open-label effectiveness trial.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lidoc | 2004 |
Pretreatment with thiopental for prevention of pain associated with propofol injection.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; | 2004 |
Improved application of Lidocaine/Prilocaine cream in children. A randomized and prospectively controlled study of two application regimes.
Topics: Anesthetics, Local; Catheterization; Child; Double-Blind Method; Drug Administration Schedule; Human | 2004 |
The analgesic effect of intravenous ketamine and lidocaine on pain after spinal cord injury.
Topics: Adult; Analgesics; Analysis of Variance; Anesthetics, Local; Cross-Over Studies; Double-Blind Method | 2004 |
The use of topical anaesthesia at children's minor lacerations: an experimental study.
Topics: Administration, Topical; Adolescent; Anesthesia, Local; Anesthetics, Local; Anxiety; Child; Female; | 2004 |
Comparison of EMLA and lidocaine iontophoresis for cannulation analgesia.
Topics: Adult; Aged; Analgesia; Anesthetics, Combined; Anesthetics, Local; Catheterization, Peripheral; Doub | 2004 |
Differential effects of peripheral ketamine and lidocaine on skin flux and hyperalgesia induced by intradermal capsaicin in humans.
Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Capsaicin; Cross-Over Studies; Double-Bli | 2004 |
Lidocaine vaginal gel versus lidocaine paracervical block for analgesia during oocyte retrieval.
Topics: Administration, Intravaginal; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anxiety; Female; F | 2004 |
[Periprostatic local anesthesia before transrectal ultrasound-guided prostate biopsy].
Topics: Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Pain; Prospective St | 2004 |
Taking the 'ouch' out - effect of buffering commercial xylocaine on infiltration and procedure pain - a prospective, randomised, double-blind, controlled trial.
Topics: Adult; Anesthetics, Local; Buffers; Double-Blind Method; Epinephrine; Humans; Intraoperative Complic | 2004 |
Periprostatic lidocaine infiltration and/or synthetic opioid (meperidine or tramadol) administration have no analgesic benefit during prostate biopsy. A prospective randomized double-blind placebo-controlled study comparing different methods.
Topics: Analgesics, Opioid; Anesthetics, Local; Biopsy; Double-Blind Method; Humans; Lidocaine; Male; Meperi | 2004 |
Cooled lignocaine gel: does it reduce urethral discomfort during instillation?
Topics: Administration, Topical; Adult; Analgesia; Anesthetics, Local; Cold Temperature; Cystoscopy; Gels; H | 2003 |
The use of intrauterine lidocaine to minimize pain during hysterosalpingography: a randomized trial.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Hysterosalpingography; Infertility, | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Intrauterine lidocaine infusion for pain management in first-trimester abortions.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Female; Humans; | 2004 |
Factors affecting pain scores during female urethral catheterization.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Catheters, | 2004 |
Study on the efficacy of ELA-Max (4% liposomal lidocaine) compared with EMLA cream (eutectic mixture of local anesthetics) using thermosensory threshold analysis in adult volunteers.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine | 2004 |
[Comparison of two methods of local anaesthesia prior to transrectal ultrasound-guided prostate biopsies].
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; P | 2004 |
[Reduction of chronic pain for non-postherpetic peripheral neuropathies after topical treatment with a lidocaine patch].
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; H | 2004 |
Reducing the pain associated with local anaesthetic infiltration for open carpal tunnel decompression.
Topics: Adult; Aged; Anesthetics, Local; Buffers; Carpal Tunnel Syndrome; Decompression, Surgical; Double-Bl | 2004 |
Instillation of anesthetic gel is no longer necessary in the era of flexible cystoscopy: a crossover study.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Cross-Over Studies | 2004 |
Prospective study comparing lidocaine 2% jelly versus sub-Tenon's anaesthesia for trabeculectomy surgery.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Female; Glaucoma; Humans; Hypnotics and Sedatives; Lido | 2004 |
Lumbar segmental nerve blocks with local anesthetics, pain relief, and motor function: a prospective double-blind study between lidocaine and ropivacaine.
Topics: Adult; Aged; Amides; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Male; Middl | 2004 |
Comparative benefit of preemptively applied thiopental for propofol injection pain: the advantage over lidocaine.
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Body Weight; Dose-Response Relationship, | 2004 |
Pain during injection of propofol: the effect of prior administration of butorphanol.
Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Butorphanol; Cross-Over Stu | 2004 |
[Analgesic effects of Emla cream and saccharose solution for subcutaneous injections in preterm newborns: a prospective study of 265 injections].
Topics: Administration, Cutaneous; Administration, Oral; Analysis of Variance; Anesthetics, Combined; Anesth | 2004 |
Use of topical application of lidocaine-prilocaine cream to reduce injection-site pain of depot antipsychotics.
Topics: Administration, Topical; Adult; Anesthetics, Local; Antipsychotic Agents; Brief Psychiatric Rating S | 2004 |
Topical lidocaine patch 5% may target a novel underlying pain mechanism in osteoarthritis.
Topics: Administration, Cutaneous; Administration, Topical; Anesthetics, Local; Female; Humans; Lidocaine; M | 2004 |
Propofol-induced injection pain: comparison of a modified propofol emulsion to standard propofol with premixed lidocaine.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Chem | 2004 |
Effectiveness of fixed 50% nitrous oxide oxygen mixture and EMLA cream for insertion of central venous catheters in children.
Topics: Adolescent; Age Distribution; Catheterization, Central Venous; Child; Child, Preschool; Female; Huma | 2004 |
Reducing pain in ED patients during lumbar puncture: the efficacy and feasibility of iontophoresis, collaborative approach.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Chi-Square Distribution; Emergency S | 2004 |
Lidocaine tape (Penles) reduces the pain of botulinum toxin injection for Meige syndrome.
Topics: Anesthesia, Local; Anesthetics, Local; Botulinum Toxins, Type A; Double-Blind Method; Female; Humans | 2004 |
Pain intensity and bioavailability of intramuscular asparaginase and a local anesthetic: a double-blinded study.
Topics: Adolescent; Anesthetics, Local; Antineoplastic Agents; Asparaginase; Biological Availability; Child; | 2005 |
Contact-topical plus intracameral lidocaine versus peribulbar anesthesia in combined surgery: a randomized clinical trial.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthesia; Anesthetics, Local; Bupivacaine; Catar | 2004 |
Comparison of Propofol-Lipuro with propofol mixed with lidocaine 10 mg on propofol injection pain.
Topics: Adolescent; Adult; Aged; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local; Chemis | 2004 |
Pain on injection: a double-blind comparison of propofol with lidocaine pretreatment versus propofol formulated with long- and medium-chain triglycerides.
Topics: Adolescent; Adult; Anesthetics, Intravenous; Anesthetics, Local; Chemistry, Pharmaceutical; Double-B | 2004 |
The intravenous ketamine test: a predictive response tool for oral dextromethorphan treatment in neuropathic pain.
Topics: Administration, Oral; Adult; Anesthetics, Local; Databases, Factual; Dextromethorphan; Excitatory Am | 2004 |
Lidocaine patch 5% and its positive impact on pain qualities in osteoarthritis: results of a pilot 2-week, open-label study using the Neuropathic Pain Scale.
Topics: Administration, Cutaneous; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Osteoar | 2004 |
The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations.
Topics: Anesthesia, Local; Anesthetics, Local; Child; Drug Therapy, Combination; Epinephrine; Female; Finger | 2004 |
A randomized controlled trial of 5% lidocaine gel for HIV-associated distal symmetric polyneuropathy.
Topics: Anesthetics, Local; Cross-Over Studies; Double-Blind Method; HIV Infections; Humans; Lidocaine; Midd | 2004 |
Sequential supraclavicular brachial plexus block and intravenous regional anaesthesia for upper limb surgery.
Topics: Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local | 2004 |
[Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides].
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Emulsions; Female; Humans; Incidence; Lidocaine; Male; | 2004 |
Quantification and analysis of pain in nonsurgical scaling and/or root planing.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Dental Scaling; Double-Bl | 2004 |
Double-blind randomized controlled trial assessing the safety and efficacy of intravesical agents for ureteral stent symptoms after extracorporeal shockwave lithotripsy.
Topics: Administration, Intravesical; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Double-Bl | 2004 |
Successful downregulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis.
Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Cystitis, Interstitial; Drug Therapy, | 2005 |
Successful downregulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis.
Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Cystitis, Interstitial; Drug Therapy, | 2005 |
Successful downregulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis.
Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Cystitis, Interstitial; Drug Therapy, | 2005 |
Successful downregulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis.
Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Cystitis, Interstitial; Drug Therapy, | 2005 |
Successful downregulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis.
Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Cystitis, Interstitial; Drug Therapy, | 2005 |
Successful downregulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis.
Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Cystitis, Interstitial; Drug Therapy, | 2005 |
Successful downregulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis.
Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Cystitis, Interstitial; Drug Therapy, | 2005 |
Successful downregulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis.
Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Cystitis, Interstitial; Drug Therapy, | 2005 |
Successful downregulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis.
Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Cystitis, Interstitial; Drug Therapy, | 2005 |
Comparison of different local anesthesia techniques during TRUS-guided biopsies: a prospective pilot study.
Topics: Adenocarcinoma; Adjuvants, Anesthesia; Administration, Rectal; Aged; Anesthesia, Local; Anesthetics, | 2005 |
Preventing pain on injection of propofol: a comparison between lignocaine pre-treatment and lignocaine added to propofol.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; Humans; Injections, Intra | 2004 |
Intravenous ketamine sedation for painful oncology procedures.
Topics: Adolescent; Analgesics; Anesthetics, Local; Biopsy, Needle; Bone Marrow Examination; Child; Child, P | 2005 |
A randomized controlled trial to evaluate S-Caine patch for reducing pain associated with vascular access in children.
Topics: Adolescent; Catheters, Indwelling; Chi-Square Distribution; Child; Child, Preschool; Drug Combinatio | 2005 |
Randomized placebo-controlled study of periprostatic local anaesthetic for transrectal ultrasound-guided prostate biopsy.
Topics: Aged; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; Pain | 2004 |
Premedication for bronchoscopy in older patients: a double-blind comparison of two regimens.
Topics: Aged; Aged, 80 and over; Bronchoscopy; Double-Blind Method; Drug Therapy, Combination; Female; Human | 2005 |
[Optimized use of Emla cream in children--secondary publication. A randomized, prospective, controlled comparison of two application regimes].
Topics: Anesthetics, Combined; Anesthetics, Local; Catheterization; Child; Double-Blind Method; Female; Huma | 2005 |
Bacteriostatic saline containing benzyl alcohol decreases the pain associated with the injection of propofol.
Topics: Adult; Anesthetics, Local; Bacteria; Benzyl Alcohol; Double-Blind Method; Female; Humans; Injections | 2005 |
Pilot study of the feasibility of in-office bladder distention using electromotive drug adminstration (EMDA).
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Cystitis, Interstitial; Cystoscopy; Feasibility Studie | 2005 |
[Application of EMLA creme before upper lid blepharoplasty].
Topics: Administration, Topical; Anesthetics; Anesthetics, Local; Blepharoplasty; Chemotherapy, Adjuvant; Fe | 2005 |
Self-warming lidocaine/tetracaine patch effectively and safely induces local anesthesia during minor dermatologic procedures.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Dermatologic Surgical | 2005 |
Randomized double-blind comparison of lidocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy.
Topics: Aged; Ambulatory Care; Anesthetics, Local; Anti-Infective Agents, Local; Chlorhexidine; Cystoscopy; | 2005 |
Randomized double-blind comparison of lidocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy.
Topics: Aged; Ambulatory Care; Anesthetics, Local; Anti-Infective Agents, Local; Chlorhexidine; Cystoscopy; | 2005 |
Randomized double-blind comparison of lidocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy.
Topics: Aged; Ambulatory Care; Anesthetics, Local; Anti-Infective Agents, Local; Chlorhexidine; Cystoscopy; | 2005 |
Randomized double-blind comparison of lidocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy.
Topics: Aged; Ambulatory Care; Anesthetics, Local; Anti-Infective Agents, Local; Chlorhexidine; Cystoscopy; | 2005 |
Ultrasound with topical anesthetic rapidly decreases pain of intravenous cannulation.
Topics: Adolescent; Adult; Anesthetics, Local; Emergency Service, Hospital; Female; Humans; Infusions, Intra | 2005 |
Rapid, needle-free delivery of lidocaine for reducing the pain of venipuncture among pediatric subjects.
Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Erythema; Female; Huma | 2005 |
Intra-cervical versus i.v. fentanyl for abortion.
Topics: Abortion, Induced; Adolescent; Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Cervix Uteri; Dou | 2005 |
Evaluation of the S-Caine Peel for induction of local anesthesia for laser-assisted tattoo removal: randomized, double-blind, placebo-controlled, multicenter study.
Topics: Administration, Topical; Adult; Anesthetics, Local; Double-Blind Method; Drug Combinations; Female; | 2005 |
Patient tolerance during outpatient flexible cystoscopy--a prospective, randomized, double-blind study comparing plain lubrication and lidocaine gel.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthetics, Local; Cystoscopy; Double-Blind Method | 2004 |
Intravenous lidocaine relieves spinal cord injury pain: a randomized controlled trial.
Topics: Adult; Aged; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female; Humans; Injections | 2005 |
Cophenylcaine spray vs. placebo in flexible nasendoscopy: a prospective double-blind randomised controlled trial.
Topics: Administration, Intranasal; Analysis of Variance; Anesthetics, Combined; Double-Blind Method; Endosc | 2005 |
Direct comparison of EMLA versus lidocaine for pain control in Nd:YAG 1,064 nm laser hair removal.
Topics: Anesthetics, Combined; Anesthetics, Local; Double-Blind Method; Female; Hair Removal; Humans; Laser | 2005 |
A lidocaine/metoclopramide combination decreases pain on injection of propofol.
Topics: Adult; Anesthetics, Intravenous; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Inj | 2005 |
A combination of lidocaine and nitrous oxide in oxygen is more effective in preventing pain on propofol injection than either treatment alone.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Double-Bli | 2005 |
Propofol injection pain in children: a prospective randomized double-blind trial of a new propofol formulation versus propofol with added lidocaine.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Intravenous; Child; Child, Preschool; Double-Blind M | 2005 |
Increased placebo analgesia over time in irritable bowel syndrome (IBS) patients is associated with desire and expectation but not endogenous opioid mechanisms.
Topics: Adult; Analgesia; Anesthetics, Local; Anxiety; Attitude to Health; Female; Humans; Irritable Bowel S | 2005 |
The effects of intravenous lidocaine on pain during injection of medium- and long-chain triglyceride propofol emulsions.
Topics: Adolescent; Adult; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Emulsions; Exc | 2005 |
Effect of nitrous oxide in reducing pain of propofol injection in adult patients.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; F | 2005 |
Liposomal lidocaine to improve procedural success rates and reduce procedural pain among children: a randomized controlled trial.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Presch | 2005 |
Effectiveness of eutectic mixture of local anesthetic cream and occlusive dressing with low dosage of fentanyl for pain control during shockwave lithotripsy.
Topics: Administration, Topical; Aged; Analgesics, Opioid; Anesthetics, Local; Drug Therapy, Combination; Fe | 2005 |
Which anaesthesia should be recommended for prostate biopsy?
Topics: Administration, Rectal; Aged; Anesthesia, Local; Anesthetics, Local; Biopsy; Decision Making; Endoso | 2005 |
Local anesthesia in transrectal ultrasound-guided prostate biopsy: EMLA cream as a new alternative technique.
Topics: Administration, Rectal; Aged; Anesthesia, Local; Anesthetics, Local; Biopsy; Endosonography; Humans; | 2005 |
Influence of local anaesthesia on pain and distress induced by two bloodless castration methods in young lambs.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Hydrocortisone; Lidocaine; Male; Orchiectomy; Pain; | 2006 |
Epidural injection of lidocaine reduces the response to dural puncture accompanying spinal needle insertion when performing combined spinal-epidural anesthesia.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Cesare | 2005 |
Intraoperative pain responses following intraovarian versus mesovarian injection of lidocaine in mares undergoing laparoscopic ovariectomy.
Topics: Anesthetics, Local; Animals; Female; Horses; Intraoperative Care; Intraoperative Period; Laparoscopy | 2005 |
Laser-assisted anesthesia prior to intravenous cannulation in volunteers: a randomized, controlled trial.
Topics: Adult; Anesthesia, Local; Catheterization, Peripheral; Combined Modality Therapy; Double-Blind Metho | 2005 |
Reduction of pain from needle stick in the oral mucosa by topical anesthetics: a comparative study between lidocaine/prilocaine and benzocaine.
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Cuspid; Humans; Lidocaine; Lidocaine, | 2005 |
Nitrous oxide inhalation is a safe and effective way to facilitate procedures in paediatric outpatient departments.
Topics: Adolescent; Analgesics; Anesthetics, Inhalation; Anxiety; Catheterization; Child; Female; Humans; Li | 2005 |
Does lidocaine gel alleviate the pain of bladder catheterization in young children? A randomized, controlled trial.
Topics: Anesthetics, Local; Double-Blind Method; Female; Gels; Humans; Infant; Lidocaine; Male; Pain; Pain M | 2005 |
Effect of local anaesthesia on short- and long-term pain induced by two bloodless castration methods in calves.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Behavior, Animal; Cattle; Cattle Diseases; Hydrocort | 2007 |
Diclofenac suppository administration in conjunction with lidocaine gel during transrectal ultrasound-guided prostate biopsy: prospective, randomized, placebo-controlled study.
Topics: Analgesia; Anesthetics, Local; Biopsy; Diclofenac; Drug Therapy, Combination; Gels; Humans; Lidocain | 2005 |
How to decrease pain at rapid injection of propofol: effectiveness of flurbiprofen.
Topics: Adult; Aged; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Female; Flurbiprofen; Humans; | 2005 |
Perianal and intrarectal anaesthesia for transrectal biopsy of the prostate: a prospective randomized study comparing lidocaine-prilocaine cream and placebo.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; Double-Bl | 2005 |
Single-center, double-blind, randomized study to evaluate the efficacy of 4% lidocaine cream versus vehicle cream during botulinum toxin type A treatments.
Topics: Administration, Topical; Adult; Anesthetics, Local; Botulinum Toxins, Type A; Double-Blind Method; E | 2005 |
A prospective, randomised, single-blinded, controlled trial comparing two topical anaesthetic modalities for the application of a tenaculum to the cervix.
Topics: Administration, Intravaginal; Adult; Anesthetics, Local; Cervix Uteri; Female; Humans; Hysterosalpin | 2005 |
Adverse effects of EMLA (lidocaine/prilocaine) cream and efficacy for the placement of jugular catheters in hospitalized cats.
Topics: Analgesia; Anesthetics, Combined; Anesthetics, Local; Animals; Cat Diseases; Catheterization, Centra | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Hydrogen-I | 2006 |
Study of a combined percutaneous local anaesthetic and the TDS system for venepuncture.
Topics: Administration, Cutaneous; Adult; Anesthesia, Local; Anesthetics, Local; Chemistry, Pharmaceutical; | 2006 |
Site of local anaesthesia in transrectal ultrasonography-guided 12-core prostate biopsy: does it make a difference?
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; N | 2006 |
Loss of expectation-related mechanisms in Alzheimer's disease makes analgesic therapies less effective.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analgesics; Attitude; Brain Mapping; Case-Control Studie | 2006 |
Effect of local lignocaine gel application for pain relief during suction termination of first-trimester pregnancy: a randomized controlled trial.
Topics: Abortion, Induced; Adolescent; Adult; Analgesia; Double-Blind Method; Female; Gels; Humans; Lidocain | 2006 |
Differential effect of ketamine and lidocaine on spontaneous and mechanical evoked pain in patients with nerve injury pain.
Topics: Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Humans; Ketamine; Lidocaine; Male; Mid | 2006 |
Comparison on pain on injection of a small particle size-lipid emulsion of propofol and standard propofol with or without lidocaine.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Fat Emulsions, Intravenous | 2005 |
Intrarectal administration of lidocaine gel versus plain lubricant gel for pain control during transrectal ultrasound-guided extensive 10-core prostate biopsy in Hong Kong Chinese population: prospective double-blind randomised controlled trial.
Topics: Administration, Rectal; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy, Needle; Double-Blind Me | 2006 |
Slow-wave photic stimulation relieves patient discomfort during esophagogastroduodenoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Butylscopolammonium Bromide; Electroencephalogra | 2006 |
Brief focal ultrasound with topical anesthetic decreases the pain of intravenous placement in children.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Attitude of Health Personnel; Catheterizati | 2006 |
Comparison of articaine 4% and lidocaine 2% in paediatric dental patients.
Topics: Adolescent; Anesthesia Recovery Period; Anesthetics, Local; Carticaine; Child; Child, Preschool; Cro | 2006 |
Effectiveness and acceptability of lidocaine spray in reducing perineal pain during spontaneous vaginal delivery: randomised controlled trial.
Topics: Administration, Topical; Analgesia, Obstetrical; Anesthetics, Local; Female; Humans; Lidocaine; Obst | 2006 |
Efficacy of intrauterine lidocaine for removal of a "lost" intrauterine device: a randomized, controlled trial.
Topics: Administration, Topical; Anesthetics, Local; Device Removal; Double-Blind Method; Female; Humans; In | 2006 |
Efficacy of intrauterine lidocaine for removal of a "lost" intrauterine device: a randomized, controlled trial.
Topics: Administration, Topical; Anesthetics, Local; Device Removal; Double-Blind Method; Female; Humans; In | 2006 |
Efficacy of intrauterine lidocaine for removal of a "lost" intrauterine device: a randomized, controlled trial.
Topics: Administration, Topical; Anesthetics, Local; Device Removal; Double-Blind Method; Female; Humans; In | 2006 |
Efficacy of intrauterine lidocaine for removal of a "lost" intrauterine device: a randomized, controlled trial.
Topics: Administration, Topical; Anesthetics, Local; Device Removal; Double-Blind Method; Female; Humans; In | 2006 |
Preventing pain during injection of propofol: effects of a new emulsion with lidocaine addition.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Emulsions; Female; Humans; Injections; Lidocaine; Male; | 2007 |
Venous occlusion with lidocaine for preventing propofol induced pain. A prospective double-blind randomized study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Double-Blind Method; Drug Comb | 2006 |
Lidocaine-prilocaine administration during transrectal ultrasound-guided prostatic biopsy: a randomized, single-blind, placebo-controlled trial.
Topics: Administration, Rectal; Aged; Anesthetics, Local; Biopsy, Needle; Endosonography; Humans; Lidocaine; | 2006 |
Tolerance of local anesthetic for transrectal ultrasound-guided prostate biopsy: our experience and a literature review.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Biop | 2006 |
Does amethocaine gel influence blood results obtained from capillary sampling?
Topics: Administration, Cutaneous; Adult; Alanine Transaminase; Alkaline Phosphatase; Anesthetics, Local; As | 2006 |
Efficacy compared between caudal block and periprostatic local anesthesia for transrectal ultrasound-guided prostate needle biopsy.
Topics: Aged; Anesthesia, Caudal; Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; | 2006 |
Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention.
Topics: Aged; Anesthetics, Local; Angioplasty, Balloon, Coronary; Bradycardia; Cardiovascular Diseases; Cons | 2007 |
Prevention of withdrawal associated with the injection of rocuronium in adults and children.
Topics: Adult; Age Factors; Androstanols; Anesthetics, Intravenous; Anesthetics, Local; Child; Child, Presch | 2006 |
Etomidate-Lipuro is associated with considerably less injection pain in children compared with propofol with added lidocaine.
Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anesthetics, Intravenous; Anest | 2006 |
Efficacy of EMLA cream to reduce fear and pain associated with interferon beta-1a injection in patients with multiple sclerosis.
Topics: Adjuvants, Immunologic; Administration, Cutaneous; Adolescent; Adult; Anesthetics, Local; Attitude t | 2006 |
Comparison of bacteriostatic normal saline and lidocaine used as intradermal anesthesia for the placement of intravenous lines.
Topics: Adult; Aged; Analgesia; Analysis of Variance; Anesthetics, Local; Catheterization, Peripheral; Clini | 2006 |
Combination of oral tramadol, acetaminophen and 1% lidocaine induced periprostatic nerve block for pain control during transrectal ultrasound guided biopsy of the prostate: a prospective, randomized, controlled trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics; Anesthetics, Local; Biopsy, Needle; Double-Bl | 2006 |
Use of lidocaine-prilocaine patch for the mantoux test: Influence on pain and reading.
Topics: Adult; Anesthetics, Local; BCG Vaccine; Drug Delivery Systems; Female; Forearm; Humans; Injections, | 2006 |
Topical anesthesia with EMLA reduces pain during endomyocardial biopsy: a randomized trial.
Topics: Administration, Topical; Anesthetics, Local; Biopsy; Catheterization; Double-Blind Method; Female; H | 2006 |
A randomized comparison of nitrous oxide plus hematoma block versus ketamine plus midazolam for emergency department forearm fracture reduction in children.
Topics: Adolescent; Analgesics; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Anxiety Agents; Child; Ch | 2006 |
Speed of injection influences efficacy of inferior alveolar nerve blocks: a double-blind randomized controlled trial in volunteers.
Topics: Adult; Anesthetics, Local; Bicuspid; Cross-Over Studies; Dental Pulp; Dental Pulp Test; Double-Blind | 2006 |
Inhaled nitrous oxide (Entonox) as a short acting sedative during bone marrow examination.
Topics: Administration, Inhalation; Anesthetics, Combined; Anesthetics, Local; Bone Marrow Examination; Drug | 2006 |
Lidocaine iontophoresis mediates analgesia in lateral epicondylalgia treatment.
Topics: Algorithms; Analgesia; Analysis of Variance; Anesthetics, Local; Female; Humans; Iontophoresis; Lido | 2006 |
Analgesia for venous cannulation by subcutaneous infiltration: effect of lidocaine concentration.
Topics: Analgesia; Anesthetics, Local; Catheterization; Drug Administration Routes; Humans; Lidocaine; Pain; | 2006 |
Topical gel vs subconjunctival lidocaine for intravitreous injection: a randomized clinical trial.
Topics: Anesthetics, Local; Conjunctiva; Gels; Glucocorticoids; Humans; Injections; Lidocaine; Pain; Pain Me | 2006 |
Topical gel vs subconjunctival lidocaine for intravitreous injection: a randomized clinical trial.
Topics: Anesthetics, Local; Conjunctiva; Gels; Glucocorticoids; Humans; Injections; Lidocaine; Pain; Pain Me | 2006 |
Topical gel vs subconjunctival lidocaine for intravitreous injection: a randomized clinical trial.
Topics: Anesthetics, Local; Conjunctiva; Gels; Glucocorticoids; Humans; Injections; Lidocaine; Pain; Pain Me | 2006 |
Topical gel vs subconjunctival lidocaine for intravitreous injection: a randomized clinical trial.
Topics: Anesthetics, Local; Conjunctiva; Gels; Glucocorticoids; Humans; Injections; Lidocaine; Pain; Pain Me | 2006 |
Topical gel vs subconjunctival lidocaine for intravitreous injection: a randomized clinical trial.
Topics: Anesthetics, Local; Conjunctiva; Gels; Glucocorticoids; Humans; Injections; Lidocaine; Pain; Pain Me | 2006 |
Topical gel vs subconjunctival lidocaine for intravitreous injection: a randomized clinical trial.
Topics: Anesthetics, Local; Conjunctiva; Gels; Glucocorticoids; Humans; Injections; Lidocaine; Pain; Pain Me | 2006 |
Topical gel vs subconjunctival lidocaine for intravitreous injection: a randomized clinical trial.
Topics: Anesthetics, Local; Conjunctiva; Gels; Glucocorticoids; Humans; Injections; Lidocaine; Pain; Pain Me | 2006 |
Topical gel vs subconjunctival lidocaine for intravitreous injection: a randomized clinical trial.
Topics: Anesthetics, Local; Conjunctiva; Gels; Glucocorticoids; Humans; Injections; Lidocaine; Pain; Pain Me | 2006 |
Topical gel vs subconjunctival lidocaine for intravitreous injection: a randomized clinical trial.
Topics: Anesthetics, Local; Conjunctiva; Gels; Glucocorticoids; Humans; Injections; Lidocaine; Pain; Pain Me | 2006 |
The pain quality assessment scale: assessment of pain quality in carpal tunnel syndrome.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Carp | 2006 |
Cisatracurium or rocuronium versus rocuronium-cisatracurium combination.
Topics: Adolescent; Adult; Androstanols; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local | 2006 |
Lidocaine pretreatment for the prevention of propofol-induced transient motor disturbances in children during anesthesia induction: a randomized controlled trial in children undergoing invasive hematologic procedures.
Topics: Analysis of Variance; Anesthesia; Anesthetics, Local; Child; Child, Preschool; Diagnostic Techniques | 2006 |
Influence of aging on lidocaine requirements for pain on injection of propofol.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Anesthesia, Intravenous; Anesthetics, Intravenou | 2006 |
Reducing pain and unpleasantness during repetitive transcranial magnetic stimulation.
Topics: Administration, Topical; Anesthetics, Local; Epinephrine; Humans; Injections, Subcutaneous; Lidocain | 2006 |
Comparison of traditional basal and apical periprostatic block: impact on injection pain and biopsy pain.
Topics: Anesthetics, Local; Humans; Injections; Lidocaine; Male; Nerve Block; Pain; Pain Measurement; Prosta | 2007 |
Combined "periprostatic and periapical" local anesthesia is not superior to "periprostatic" anesthesia alone in reducing pain during Tru-Cut prostate biopsy.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Biopsy; Endosonography; Humans; Inje | 2006 |
Local anesthesia for radial artery cannulation: a comparison of a lidocaine-prilocaine emulsion and lidocaine infiltration.
Topics: Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Female; Humans; Injections, Subc | 1988 |
Intracervical block and pain perception during the performance of a hysterosalpingogram: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Cervix Uteri; Female; Humans; Hysterosalpingography; Lidocaine; Pain | 2007 |
Intracervical block and pain perception during the performance of a hysterosalpingogram: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Cervix Uteri; Female; Humans; Hysterosalpingography; Lidocaine; Pain | 2007 |
Intracervical block and pain perception during the performance of a hysterosalpingogram: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Cervix Uteri; Female; Humans; Hysterosalpingography; Lidocaine; Pain | 2007 |
Intracervical block and pain perception during the performance of a hysterosalpingogram: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Cervix Uteri; Female; Humans; Hysterosalpingography; Lidocaine; Pain | 2007 |
Comparison of diphenhydramine and lidocaine for prevention of pain after injection of propofol: a double-blind, placebo-controlled, randomized study.
Topics: Adult; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Diphenhydramine; Double-B | 2007 |
Assessor status influences pain recall.
Topics: Affect; Aged; Anesthetics, Local; Female; Follow-Up Studies; Humans; Lidocaine; Low Back Pain; Male; | 2007 |
Effects of local anaesthesia on subdermal needle insertion pain and subsequent tests of microvascular function in human.
Topics: Administration, Topical; Adult; Anesthetics, Combined; Anesthetics, Local; Blood Flow Velocity; Dose | 2007 |
Reduction of pain on injection of propofol: combination of pretreatment of remifentanil and premixture of lidocaine with propofol.
Topics: Adult; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Drug | 2007 |
Local infiltration of epinephrine-containing lidocaine with bicarbonate reduces superficial bleeding and pain during labor epidural catheter insertion: a randomized trial.
Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Catheterizatio | 2007 |
Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline: a randomized, side-by-side, double-blind study.
Topics: Adolescent; Adult; Anesthetics, Local; Axilla; Botulinum Toxins, Type A; Double-Blind Method; Drug C | 2007 |
Safety and tolerability of sedation-free flexible cystoscopy for intradetrusor botulinum toxin-A injection.
Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Cystoscopy; Female; Huma | 2007 |
The effect of a eutectic mixture of local anesthetic cream on wrist pain during transradial coronary procedures.
Topics: Aged; Analysis of Variance; Anesthesia, Local; Cardiac Catheterization; Case-Control Studies; Cathet | 2007 |
Intrauterine lidocaine plus buccal misoprostol in the endometrial biopsy.
Topics: Administration, Intravaginal; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics, Combined | 2007 |
Comparison of topical anesthetics (EMLA/Oraqix vs. benzocaine) on pain experienced during palatal needle injection.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Benzocaine; Gels; Humans; Injectio | 2007 |
Transdermal diclofenac patch vs eutectic mixture of local anesthetics for venous cannulation pain.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Diclofenac; Double-Blind | 2007 |
[Evaluation of analgesic protocol with nitrous oxide and EMLA cream during botulinum toxin injections in children].
Topics: Adolescent; Analgesics, Non-Narcotic; Anesthetics, Local; Botulinum Toxins, Type A; Cerebral Palsy; | 2007 |
Proof of systemic safety of a lidocaine ointment in the treatment of patients with anorectal pain.
Topics: Adult; Anal Canal; Anesthetics, Local; Area Under Curve; Electrocardiography; Female; Half-Life; Hum | 2007 |
Lidocaine is more efficient than the choice of propofol formulations to reduce incidence of pain on induction.
Topics: Adult; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Emu | 2007 |
A comparison of laser-assisted drug delivery at two output energies for enhancing the delivery of topically applied LMX-4 cream prior to venipuncture.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Drug De | 2007 |
A comparison of laser-assisted drug delivery at two output energies for enhancing the delivery of topically applied LMX-4 cream prior to venipuncture.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Drug De | 2007 |
A comparison of laser-assisted drug delivery at two output energies for enhancing the delivery of topically applied LMX-4 cream prior to venipuncture.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Drug De | 2007 |
A comparison of laser-assisted drug delivery at two output energies for enhancing the delivery of topically applied LMX-4 cream prior to venipuncture.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Drug De | 2007 |
Case series on chronic whiplash related neck pain treated with intraarticular zygapophysial joint regeneration injection therapy.
Topics: Adult; Anesthetics, Local; Cervical Vertebrae; Chronic Disease; Disability Evaluation; Female; Follo | 2007 |
Subtenon lidocaine vs topical proparacaine in adult strabismus surgery.
Topics: Administration, Topical; Adult; Anesthetics, Local; Eye; Humans; Injections; Intraoperative Period; | 2006 |
Nociception after intraperitoneal injection of a sodium pentobarbitone formulation with and without lidocaine in rats quantified by expression of neuronal c-fos in the spinal cord--a preliminary study.
Topics: Anesthetics, Local; Animals; Hypnotics and Sedatives; Lidocaine; Male; Neurons; Pain; Pain Measureme | 2007 |
Randomised trial showing that lidocaine should be "squirted" through a peritoneal drain before it is removed.
Topics: Anesthetics, Local; Device Removal; Female; Gynecologic Surgical Procedures; Humans; Lidocaine; Pain | 2007 |
Low-dose botulinum toxin type A for the treatment of refractory piriformis syndrome.
Topics: Adult; Anesthetics, Local; Asian People; Botulinum Toxins, Type A; Dexamethasone; Female; Glucocorti | 2007 |
Needle-free delivery of lidocaine for reducing the pain associated with the fine-needle aspiration biopsy of thyroid nodules: time-saving and efficacious procedure.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Biopsy, Fine-Needle; Female; Humans; | 2007 |
Local anaesthetic reduces the pain of drain tube removal.
Topics: Abdomen; Anesthetics, Local; Double-Blind Method; Drainage; Humans; Injections; Lidocaine; Pain; Pai | 2007 |
Expanding the use of topical anesthesia in wound management: sequential layered application of topical lidocaine with epinephrine.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Dose-Response Relationship, Drug; Dr | 2007 |
Effectiveness of a topical salve (Dynexan) on pain sensitivity and early wound healing following nonsurgical periodontal therapy.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Dental Scaling; Double-Blind Method; Femal | 2007 |
Multimodal analgesia to prevent propofol-induced pain: pretreatment with remifentanil and lidocaine versus remifentanil or lidocaine alone.
Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Lido | 2007 |
A randomized controlled trial of topical glyceryl trinitrate before transrectal ultrasonography-guided biopsy of the prostate.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy, Needle; Humans; | 2007 |
A combination of lidocaine (lignocaine) and remifentanil reduces pain during propofol injection.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Bl | 2007 |
A ketamine-propofol admixture does not reduce the pain on injection compared with a lidocaine-propofol admixture.
Topics: Anesthesia; Anesthetics, Intravenous; Child; Child, Preschool; Double-Blind Method; Drug Combination | 2007 |
[Tolerability and complications of ultrasound guided prostate biopsies with intrarectal lidocaine gel].
Topics: Administration, Rectal; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy, Needle; Gels; Humans; L | 2007 |
Eutectic mixture of local anesthetic (EMLA) decreases pain during humeral block placement in nonsedated patients.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Double-Blind Method; Elective Surgical Pro | 2007 |
Comparison of lignocaine and water-based lubricating gels for female urethral catheterization: a randomized controlled trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Fe | 2007 |
Effect of neurolytic celiac plexus block guided by computerized tomography on pancreatic cancer pain.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Celiac Plexus; Female; Humans; Lidocaine; Male; | 2008 |
Prevention of pain due to injection of propofol with IV administration of lidocaine 40 mg + metoclopramide 2.5, 5, or 10 mg or saline: a randomized, double-blind study in Japanese adult surgical patients.
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Dose-Response Relationship, | 2007 |
A study comparing chloroprocaine with lidocaine for skin infiltration before intravenous catheter insertion.
Topics: Adult; Analysis of Variance; Anesthetics, Local; Attitude to Health; Catheterization, Peripheral; Cl | 2007 |
Use of the Synera patch for local anesthesia before vascular access procedures: a randomized, double-blind, placebo-controlled study.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Double-Blind Method; Drug Combinations; Female | 2007 |
Is topical local anaesthesia necessary when performing paediatric flexible nasendoscopy? A double-blind randomized controlled trial.
Topics: Administration, Topical; Anesthetics, Local; Anxiety; Child; Double-Blind Method; Drug Combinations; | 2007 |
Pain on injection of propofol: propofol LCT vs propofol MCT/LCT with or without lidocaine pretreatment.
Topics: Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Chi-Square Distribution; Female; | 2006 |
Preventing pain during office biopsy of the prostate: a single center, prospective, double-blind, 3-arm, parallel group, randomized clinical trial.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Biopsy; Diagnosis, Differential; Double-Blind Method; H | 2007 |
Analgesic and antinociceptive effects of peripheral nerve neurostimulation in an advanced human experimental model.
Topics: Adult; Anesthetics, Local; Conditioning, Psychological; Electric Stimulation Therapy; Evoked Potenti | 2008 |
Topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; Follow-Up | 2008 |
Lignocaine is a better analgesic than either ethyl chloride or nitrous oxide for peripheral intravenous cannulation.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anesthetics, Loca | 2007 |
Comparative evaluation of myolaxin and EMLA cream for attenuation of venous cannulation pain: a prospective, randomised, double blind study.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Capsaicin; Catheterization, Periphe | 2007 |
Efficacy of intravenous acetaminophen and lidocaine on propofol injection pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Anesthetics, Local; Double | 2008 |
Effect of narcotic pretreatment on pain after rocuronium injection: a randomized, double-blind controlled comparison with lidocaine.
Topics: Adult; Androstanols; Double-Blind Method; Female; Fentanyl; Humans; Injections, Intravenous; Lidocai | 2007 |
Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; | 2007 |
Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; | 2007 |
Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; | 2007 |
Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; | 2007 |
Extra-articular steroid injection: early patient response and the incidence of flare reaction.
Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; De Quervain Disease; Double-Blind M | 2007 |
Topical amitriptyline versus lidocaine in the treatment of neuropathic pain.
Topics: Administration, Topical; Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Local; Double-Blind M | 2008 |
Galactography without discomfort using lidocaine/prilocaine anesthetic cream.
Topics: Adult; Aged; Anesthetics, Local; Breast Diseases; Catheterization; Contrast Media; Humans; Lidocaine | 2008 |
A novel needle-free powder lidocaine delivery system for rapid local analgesia.
Topics: Adolescent; Age Factors; Anesthesia, Local; Anesthetics, Local; Child; Child, Preschool; Confidence | 2008 |
The effect of 50% glycolic acid on the percutaneous absorption of eutectic mixture of local anesthetics (EMLA): a study of the electrofulguration-induced pain.
Topics: Adolescent; Adult; Anesthetics, Local; Double-Blind Method; Drug Synergism; Drug Therapy, Combinatio | 2008 |
Brief report: a randomized controlled trial of Synera versus lidocaine for epidural needle insertion in labouring parturients.
Topics: Administration, Cutaneous; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; D | 2008 |
Comparison of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, parallel-group, placebo-controlled study.
Topics: Adult; Aged; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; | 2008 |
Reduction of topical anesthetic onset time using ultrasound: a randomized controlled trial prior to venipuncture in young children.
Topics: Administration, Topical; Anesthetics, Local; Child; Child, Preschool; Female; Humans; Lidocaine; Mal | 2008 |
Anesthesia for phacotrabeculectomy.
Topics: Aged; Aged, 80 and over; Anesthesia; Cataract Extraction; Female; Gels; Glaucoma; Humans; Intraopera | 2008 |
Warm lidocaine/tetracaine patch versus placebo before pediatric intravenous cannulation: a randomized controlled trial.
Topics: Administration, Cutaneous; Adolescent; Anesthesia, Local; Anesthetics, Local; Catheterization, Perip | 2008 |
Patient tolerance during cystoscopy: a randomized study comparing lidocaine hydrochloride gel and dimethyl sulfoxide with lidocaine.
Topics: Adult; Aged; Ambulatory Care; Anesthetics, Local; Cystoscopy; Dimethyl Sulfoxide; Drug Combinations; | 2008 |
Needle-free powder lidocaine delivery system provides rapid effective analgesia for venipuncture or cannulation pain in children: randomized, double-blind Comparison of Venipuncture and Venous Cannulation Pain After Fast-Onset Needle-Free Powder Lidocaine
Topics: Administration, Cutaneous; Adolescent; Analgesia; Anesthetics, Local; Catheterization, Peripheral; C | 2008 |
EMLA cream and nitrous oxide to alleviate pain induced by palivizumab (Synagis) intramuscular injections in infants and young children.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Antibodies, Monoclonal; Antibodies, Monoclonal, Humani | 2008 |
Eye irrigation is more comfortable with a lidocaine: containing irrigation solution compared with normal saline.
Topics: Anesthetics, Local; Double-Blind Method; Eye; Humans; Lidocaine; Pain; Sodium Chloride; Therapeutic | 2008 |
Comparison of lidocaine suppositories and periprostatic nerve block during transrectal prostate biopsy.
Topics: Anesthetics, Local; Biopsy; Double-Blind Method; Humans; Lidocaine; Male; Nerve Block; Pain; Prospec | 2008 |
Pharmacokinetics and tolerance of ceftriaxone in humans after single-dose intramuscular administration in water and lidocaine diluents.
Topics: Adult; Cefotaxime; Ceftriaxone; Excipients; Humans; Injections, Intramuscular; Kinetics; Lidocaine; | 1982 |
Regional anesthesia during newborn circumcision. Effect on infant pain response.
Topics: Anesthesia, Local; Circumcision, Male; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Hu | 1983 |
Topical anaesthesia with EMLA, a new lidocaine-prilocaine cream and the Cusum technique for detection of minimal application time.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Catheteriza | 1983 |
Painless venipuncture. A clinical trial of iontophoresis of lidocaine for venipuncture in blood donors.
Topics: Anesthesia, Local; Blood Donors; Clinical Trials as Topic; Double-Blind Method; Humans; Iontophoresi | 1984 |
A controlled trial of pain on skin infiltration with local anaesthetics.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Epinephrine; Hu | 1984 |
Comparison of injection techniques for shoulder pain: results of a double blind, randomised study.
Topics: Acromioclavicular Joint; Adult; Aged; Bursitis; Clinical Trials as Topic; Double-Blind Method; Femal | 1983 |
Pain-free venepuncture. Effect of timing of application of local anaesthetic cream.
Topics: Adolescent; Anesthetics, Local; Catheterization; Child; Child, Preschool; Double-Blind Method; Drug | 1984 |
Lidocaine and the reduction of post-venographic pain.
Topics: Aged; Double-Blind Method; Female; Humans; Lidocaine; Male; Pain; Phlebography; Random Allocation | 1984 |
Forum. A comparison between the midline and paramedian approaches to the extradural space.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Epinephrine; Female; Humans; Lidocaine; | 1984 |
[Contrast media and pain in peripheral arteriography. Randomized, intra-individual double-blind trial: ioglicinate, ioglicinate-lidocaine, ioxaglate].
Topics: Angiography; Arterial Occlusive Diseases; Clinical Trials as Topic; Contrast Media; Double-Blind Met | 1982 |
Femoral artery flow and pain during lumbar aortography: comparison of ionic and non-ionic contrast media.
Topics: Aged; Aortography; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Female; Femoral Artery; Human | 1983 |
Comparison of pain and heat sensation of contrast media in aortofemoral angiography: meglumine-amidotrizoate (Angiografin) mixed with lidocaine versus sodium-meglumine-ioxaglate (Hexabrix).
Topics: Aortography; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Double-Blind Method; Female; Humans | 1983 |
The pharmacological effect of xylocaine topical anaesthetic--a comparison with a placebo.
Topics: Administration, Topical; Adult; Asian People; Humans; Injections; Lidocaine; Ointments; Pain; Placeb | 1981 |
Toward less painful anesthesia: water, saline, and lidocaine.
Topics: Anesthesia, Local; Anesthetics; Clinical Trials as Topic; Double-Blind Method; Humans; Injections, I | 1981 |
Reduction of pain on injection of etomidate.
Topics: Adult; Anesthesia, Intravenous; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Et | 1981 |
The prevention of pain on injection. A study of the effect of intravenous lignocaine before methohexitone.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Clinical Trials as Topic; Double-Blind Method; Fem | 1981 |
EMLA--a eutectic mixture of local anaesthetics for topical anaesthesia.
Topics: Adolescent; Anesthesia, Local; Catheterization; Child; Double-Blind Method; Drug Combinations; Femal | 1982 |
Anaesthesia for bronchoscopy: examination of a standard technique.
Topics: Adult; Aged; Anesthesia, Intravenous; Awareness; Bronchoscopy; Female; Humans; Lidocaine; Male; Meth | 1980 |
The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial.
Topics: Administration, Topical; Adult; Anxiety; Autonomic Nerve Block; Chronic Disease; Depression; Double- | 1995 |
Randomized double-blind controlled trial comparing room-temperature and heated lidocaine for digital nerve block.
Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Hot Temperature; Humans; Injections; Lidoc | 1995 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
A controlled trial of regional sympatholysis in the treatment of photo-oculodynia syndrome.
Topics: Adult; Aged; Anesthetics, Local; Blepharospasm; Bupivacaine; Double-Blind Method; Dry Eye Syndromes; | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Intranasal anesthetic effects of lidocaine and tetracaine compared.
Topics: Administration, Intranasal; Adult; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Middl | 1995 |
Intravenous regional anesthesia using lidocaine and ketorolac.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Conduction; Anesthesia, Intravenous; Anti-Infla | 1995 |
Use of a eutectic mixture of local anesthetics for prolonged subcutaneous drug administration.
Topics: Anesthetics, Local; beta-Thalassemia; Deferoxamine; Double-Blind Method; Drug Combinations; Female; | 1995 |
Comparison of plain, warmed, and buffered lidocaine for anesthesia of traumatic wounds.
Topics: Adolescent; Adult; Anesthesia, Local; Buffers; Hot Temperature; Humans; Lidocaine; Pain; Pain Measur | 1995 |
Does topical lidocaine attenuate the pain of infiltration of buffered lidocaine?
Topics: Administration, Cutaneous; Adolescent; Adult; Anesthesia, Local; Double-Blind Method; Emergencies; F | 1995 |
Neutralizing pH of lidocaine reduces pain during Norplant system insertion procedure.
Topics: Adolescent; Adult; Anesthesia, Local; Buffers; Double-Blind Method; Female; Humans; Hydrogen-Ion Con | 1995 |
Analgesia for venous cannulation: a comparison of EMLA (5 minutes application), lignocaine, ethyl chloride, and nothing.
Topics: Adult; Analgesia; Anesthetics, Local; Catheterization, Peripheral; Drug Combinations; Ethyl Chloride | 1995 |
The influence of adrenalin on the pharmacokinetics of interpleurally administered lidocaine in patients with pancreatic neoplasia.
Topics: Absorption; Adult; Analgesia; Chronic Disease; Epinephrine; Female; Half-Life; Humans; Lidocaine; Ma | 1995 |
Buffered lidocaine: analgesia for intravenous line placement in children.
Topics: Adolescent; Anesthesia, Local; Buffers; Child; Female; Humans; Infusions, Intravenous; Injections, I | 1995 |
Can topical lignocaine reduce behavioural response to heel prick?
Topics: Administration, Topical; Blood Specimen Collection; Double-Blind Method; Facial Expression; Heel; Hu | 1995 |
Peribulbar anaesthesia. A clinical evaluation of two different anaesthetic mixtures.
Topics: Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cataract Extraction; Drug Combinations; Epinephr | 1994 |
Double-blind randomized crossover study comparing intracorporeal prostaglandin E1 with combination of prostaglandin E1 and lidocaine in the treatment of organic impotence.
Topics: Adult; Alprostadil; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Erectile Dys | 1995 |
A comparison of anesthetic techniques for awake intubation in neurosurgical patients.
Topics: Adult; Anesthesia, Local; Blood Pressure; Carbon Dioxide; Cervical Vertebrae; Female; Glossopharynge | 1995 |
Prilocaine reduces injection pain caused by propofol.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anesthesia, Intravenous; Anti-Inflammatory Agents, Non-Steroi | 1995 |
Modulating effects of lignocaine on propofol.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Anesthesia, Intravenous; Female; Forearm; Hand; Hu | 1995 |
Rationalizing venepuncture pain: comparison of lignocaine injection, Butterfly (21 gauge and 23 gauge) and Venflon (20 gauge).
Topics: Adolescent; Adult; Bloodletting; Catheterization, Peripheral; Diazepam; Equipment Design; Female; Hu | 1995 |
Pain after subcutaneous injection of recombinant human erythropoietin: does Emla cream help?
Topics: Adult; Aged; Anemia; Anesthetics, Local; Double-Blind Method; Drug Combinations; Erythropoietin; Fem | 1994 |
Propofol injection pain: comparing the addition of lignocaine or metoclopramide.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Blood Pressure; Extrapyramidal Tracts; F | 1994 |
A comparison of amethocaine cream with lignocaine-prilocaine cream (EMLA) for reducing pain during retrobulbar injection.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Cataract Extraction; Double-Blind Method; Drug Combinat | 1994 |
Tetracaine, epinephrine (adrenalin), and cocaine (TAC) versus lidocaine, epinephrine, and tetracaine (LET) for anesthesia of lacerations in children.
Topics: Adolescent; Anesthesia, Local; Child; Child, Preschool; Cocaine; Double-Blind Method; Drug Combinati | 1995 |
Lidocaine for the alleviation of pain associated with subcutaneous erythropoietin injection.
Topics: Adolescent; Child; Child, Preschool; Cross-Over Studies; Erythropoietin; Female; Hematocrit; Humans; | 1994 |
LAT (lidocaine-adrenaline-tetracaine) versus TAC (tetracaine-adrenaline-cocaine) for topical anesthesia in face and scalp lacerations.
Topics: Adult; Anesthetics, Local; Cocaine; Double-Blind Method; Drug Combinations; Drug Costs; Epinephrine; | 1995 |
Cutaneous iontophoretic application of condensed lidocaine.
Topics: Administration, Cutaneous; Adult; Anesthesia, Local; Erythema; Female; Forearm; Humans; Iontophoresi | 1994 |
An assessment of prilocaine as a topical anaesthetic agent for fibreoptic bronchoscopy in comparison with lidocaine.
Topics: Adult; Aged; Anesthetics; Anesthetics, Local; Bronchoscopy; Conscious Sedation; Double-Blind Method; | 1994 |
Does a mid-lumbar block level provide adequate anaesthesia for transurethral prostatectomy?
Topics: Aged; Anesthesia, Spinal; Blood Pressure; Bupivacaine; Humans; Intraoperative Complications; Lidocai | 1994 |
Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia.
Topics: Adult; Anesthetics; Benzyl Alcohol; Benzyl Alcohols; Double-Blind Method; Drug Combinations; Humans; | 1994 |
An alternative for needle pain. Report of the Edmonton EMLA Study.
Topics: Anesthetics, Local; Child; Drug Combinations; Female; Humans; Injections; Lidocaine; Lidocaine, Pril | 1994 |
Addition of atracurium to lidocaine for intravenous regional anaesthesia.
Topics: Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Atracurium; Female; Finger Injuries; Fractur | 1994 |
Pain during injection of propofol. The effect of prior administration of thiopentone.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Ma | 1994 |
Placebo effect of eutectic mixture of lidocaine and prilocaine (EMLA) cream in reducing venepuncture pain in children.
Topics: Anesthesiology; Anesthetics, Local; Bloodletting; Child; Child, Preschool; Double-Blind Method; Drug | 1994 |
Comparison of pH-adjusted bupivacaine 0.75% and a mixture of bupivacaine 0.75% and lidocaine 2%, both with hyaluronidase, in day-case cataract surgery under regional anesthesia.
Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Local; Bupivacaine; Cataract Extraction; Diplopia; | 1994 |
Alkalisation of lignocaine-adrenaline reduces the amount of pain during subcutaneous injection of local anaesthetic.
Topics: Adult; Aged; Anesthesia, Local; Double-Blind Method; Epinephrine; Female; Humans; Hydrogen-Ion Conce | 1994 |
Pain of injection and duration of anesthesia for intradermal infiltration of lidocaine, bupivacaine, and etidocaine.
Topics: Adult; Anesthesia, Conduction; Bupivacaine; Double-Blind Method; Etidocaine; Female; Humans; Injecti | 1994 |
Pain on injection of propofol.
Topics: Adult; Anesthesia, Intravenous; Anesthesia, Local; Chi-Square Distribution; Double-Blind Method; Fem | 1994 |
The "mini-Bier's block": a new technique for prevention of tourniquet pain during axillary brachial plexus anaesthesia.
Topics: Adolescent; Adult; Axilla; Axillary Artery; Brachial Plexus; Bupivacaine; Elbow; Female; Humans; Lid | 1994 |
Comparison of iontophoresis of lidocaine with a eutectic mixture of lidocaine and prilocaine (EMLA) for topically administered local anesthesia.
Topics: Administration, Cutaneous; Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Drug C | 1994 |
Trial of a topically administered local anesthetic (EMLA cream) for pain relief during central venous port accesses in children with cancer.
Topics: Administration, Cutaneous; Adolescent; Adult; Anesthetics, Local; Antineoplastic Agents; Child; Chil | 1994 |
Comparison of percutaneous anaesthesia for venous cannulation after topical application of either amethocaine or EMLA cream.
Topics: Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Double-Blind | 1994 |
A multicentre randomized study of single-unit dose package of EMLA patch vs EMLA 5% cream for venepuncture in children.
Topics: Adhesiveness; Administration, Cutaneous; Analgesics; Anesthetics, Local; Bloodletting; Child; Child, | 1994 |
A double-blind placebo controlled study of a 5% lidocaine/prilocaine cream (EMLA) for topical anesthesia during thermolysis.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Drug Combinatio | 1994 |
Lack of effect of intraarticular corticosteroids for chronic pain in the cervical zygapophyseal joints.
Topics: Adult; Anesthetics, Local; Betamethasone; Bupivacaine; Cervical Vertebrae; Chronic Disease; Double-B | 1994 |
Flexible cystoscopy in men: is topical anaesthesia with lignocaine gel worthwhile?
Topics: Aged; Anesthesia, Local; Cystoscopy; Double-Blind Method; Gels; Humans; Lidocaine; Male; Middle Aged | 1994 |
Reducing the pain of local anesthetic infiltration: warming and buffering have a synergistic effect.
Topics: Adult; Anesthesia, Local; Buffers; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged | 1994 |
Lidocaine as a diluent for ceftriaxone in the treatment of gonorrhea. Does it reduce the pain of the injection?
Topics: Adolescent; Adult; Ceftriaxone; Female; Gonorrhea; Humans; Injections, Intramuscular; Lidocaine; Mal | 1994 |
Use of lidocaine-prilocaine cream for vaccination pain in infants.
Topics: Anesthetics, Local; Diphtheria-Tetanus-Pertussis Vaccine; Double-Blind Method; Drug Combinations; Fe | 1994 |
Age-related response to lidocaine-prilocaine (EMLA) emulsion and effect of music distraction on the pain of intravenous cannulation.
Topics: Adolescent; Age Factors; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; D | 1994 |
A study on the usefulness of local anaesthesia for the laser vaporization of conizations in the uterine cervix.
Topics: Adult; Anesthesia, Local; Female; Humans; Laser Therapy; Lidocaine; Pain; Patient Acceptance of Heal | 1994 |
The effects of intraurethral lidocaine anesthetic and patient anxiety on pain perception during cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anxiety; Cystoscopy; Double-Blind Method; Female; | 1994 |
Validation of diphenhydramine as a dermal local anesthetic.
Topics: Adult; Anesthesia, Local; Diphenhydramine; Double-Blind Method; Female; Humans; Injections, Intrader | 1994 |
1% lidocaine versus 0.5% diphenhydramine for local anesthesia in minor laceration repair.
Topics: Adult; Anesthesia, Local; Diphenhydramine; Double-Blind Method; Emergency Service, Hospital; Female; | 1994 |
Alleviation of the pain of heel prick in preterm infants.
Topics: Anesthetics, Local; Blood Gas Monitoring, Transcutaneous; Blood Specimen Collection; Carbon Dioxide; | 1994 |
Intra-arterial versus intravenous regional analgesia for hand surgery.
Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, Intravenous; Brachial Artery; Female; Hand; Humans; | 1993 |
Analgesic effect of lidocaine ointment on intact skin in neonates.
Topics: Administration, Topical; Double-Blind Method; Female; Heart Rate; Heel; Humans; Infant, Newborn; Lid | 1993 |
Comparative local anaesthetic blocks in the diagnosis of cervical zygapophysial joint pain.
Topics: Adult; Aged; Anesthetics, Local; Arthrography; Bupivacaine; Cervical Vertebrae; Chronic Disease; Dou | 1993 |
The EMLA patch--a new type of local anaesthetic application for dermal analgesia in children.
Topics: Adolescent; Analgesia; Anesthetics, Local; Bloodletting; Child; Child, Preschool; Drug Combinations; | 1994 |
Dermal patch anaesthesia: comparison of 10% lignocaine gel with absorption promoter and EMLA cream.
Topics: Administration, Cutaneous; Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Drug C | 1993 |
Effect of a topical anesthetic cream (EMLA) in reducing pain caused by infiltration of local anesthetic in eyelid surgery.
Topics: Aged; Anesthetics, Local; Double-Blind Method; Drug Combinations; Eyelid Diseases; Female; Humans; L | 1993 |
A prospective study of diagnostic epidural blockade in the assessment of chronic back and leg pain.
Topics: Adult; Aged; Anesthesia, Epidural; Back Pain; Diagnosis, Differential; Female; Humans; Leg; Lidocain | 1993 |
Double-blinded comparison of diphenhydramine versus lidocaine as a local anesthetic.
Topics: Adult; Anesthetics, Local; Diphenhydramine; Double-Blind Method; Drug Hypersensitivity; Humans; Inje | 1993 |
Intralesional vinblastine for cutaneous Kaposi's sarcoma associated with acquired immunodeficiency syndrome. A clinical trial to evaluate efficacy and discomfort associated with infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Bicarbonates; Buffers; Humans; Injections, Intralesional; | 1993 |
Buffered versus plain lidocaine for digital nerve blocks.
Topics: Adolescent; Adult; Bicarbonates; Buffers; Double-Blind Method; Female; Fingers; Humans; Injections; | 1993 |
Less painful alternatives for local anesthesia.
Topics: Adult; Aged; Anesthesia, Local; Bicarbonates; Buffers; Double-Blind Method; Epinephrine; Humans; Inj | 1993 |
Safety and efficacy of a topical anesthetic for neonatal circumcision.
Topics: Anesthesia, Local; Circumcision, Male; Double-Blind Method; Humans; Infant, Newborn; Lidocaine; Male | 1993 |
A eutectic mixture of lidocaine and prilocaine for alleviating vaccination pain in infants.
Topics: Anesthesia, Local; Child, Preschool; Double-Blind Method; Drug Combinations; Female; Humans; Infant; | 1993 |
Regional intracoronary analgesia during percutaneous transluminal coronary angioplasty.
Topics: Aged; Analgesia; Angioplasty, Balloon; Coronary Vessels; Double-Blind Method; Echocardiography; Elec | 1993 |
Comparison of the effect of EMLA cream, subcutaneous ring anaesthesia and a double cuff technique in the prevention of tourniquet pain.
Topics: Adolescent; Adult; Aged; Anesthesia, Conduction; Anesthetics, Local; Drug Combinations; Female; Huma | 1993 |
A comparison of EMLA cream versus nitrous oxide for pediatric venous cannulation.
Topics: Administration, Topical; Analgesics, Non-Narcotic; Anesthetics, Local; Anxiety; Catheterization, Per | 1995 |
Warming lignocaine reduces the pain of injection during peribulbar local anaesthesia for cataract surgery.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Cataract Extraction; Double-Blind Method; Female; Hot Te | 1995 |
The use of lignocaine to reduce pain on i.v. injection of diluted nalbuphine.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Local; Child; Double-Blind Method; Drug Combinat | 1995 |
[Efficacy of the EMLA cream in the reduction of pain caused by venipuncture in children premedicated with oral midazolam].
Topics: Adjuvants, Anesthesia; Administration, Oral; Anesthetics, Local; Child; Child, Preschool; Drug Combi | 1995 |
Thiopentone pretreatment for propofol injection pain in ambulatory patients.
Topics: Adolescent; Adult; Ambulatory Care; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Intr | 1995 |
Comparison of topical anesthetics without cocaine to tetracaine-adrenaline-cocaine and lidocaine infiltration during repair of lacerations: bupivacaine-norepinephrine is an effective new topical anesthetic agent.
Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Coc | 1996 |
Comparison of bupivacaine and lidocaine/bupivacaine for local anesthesia/digital nerve block.
Topics: Adult; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Fingers; Humans; Lidocaine; Mal | 1996 |
Does a local anaesthetic cream (EMLA) alleviate pain from heel-lancing in neonates?
Topics: Anesthetics, Local; Double-Blind Method; Drug Combinations; Female; Heel; Humans; Infant, Newborn; L | 1995 |
Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Double-Blind Method; Femal | 1995 |
Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Double-Blind Method; Femal | 1995 |
Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Double-Blind Method; Femal | 1995 |
Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Double-Blind Method; Femal | 1995 |
Prevention of pain on injection of propofol: a comparison of lidocaine with alfentanil.
Topics: Adolescent; Adult; Aged; Alfentanil; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intra | 1996 |
Does warming local anesthetic reduce the pain of subcutaneous injection?
Topics: Adult; Anesthetics, Local; Cross-Over Studies; Hot Temperature; Humans; Injections, Subcutaneous; Li | 1996 |
The effect of solution temperature on the pain of peribulbar anesthesia.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Body Temperature; Bupivacaine; Cataract Extraction; Dru | 1996 |
Analgesic and anti-inflammatory effects of lignocaine-prilocaine (EMLA) cream in human burn injury.
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Burns; Double-Blind Method; Drug | 1996 |
[EMLA cream in hematology].
Topics: Adolescent; Adult; Anesthesia, General; Anesthetics; Anesthetics, Local; Child; Child, Preschool; Dr | 1995 |
Leg and back pain after spinal anaesthesia involving hyperbaric 5% lignocaine.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Female; Humans; Leg; Lidocai | 1996 |
Modification of pain on injection of propofol. A comparison of pethidine and lignocaine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female | 1996 |
Topical ibuprofen for skin analgesia prior to venepuncture.
Topics: Administration, Topical; Analgesia; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cat | 1996 |
The analgesic response to intravenous lidocaine in the treatment of neuropathic pain.
Topics: Adult; Aged; Analgesia; Anesthetics, Local; Dose-Response Relationship, Drug; Female; Humans; Infusi | 1996 |
The effect of calcium channel antagonist administered by iontophoresis on the pain threshold.
Topics: Adult; Calcium Channel Blockers; Diltiazem; Drug Combinations; Female; Humans; Iontophoresis; Lidoca | 1995 |
EMLA prevents pain during local anesthesia for cataract surgery.
Topics: Anesthesia, Local; Anesthetics, Local; Cataract Extraction; Double-Blind Method; Drug Combinations; | 1995 |
Topical versus peribulbar anesthesia in clear corneal cataract surgery.
Topics: Administration, Topical; Aged; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cornea; Cross-Ove | 1996 |
Lignocaine with adrenaline: is it as effective as cocaine in rhinological practice?
Topics: Adult; Airway Resistance; Anesthesia, Local; Anesthetics, Local; Blood Volume; Cocaine; Double-Blind | 1996 |
A double-blind randomised comparison of the effects of epidural clonidine, lignocaine and the combination of clonidine and lignocaine in patients with chronic pain.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Analgesia, Epidural; Anesthetics, Local; Chronic Disease; Cl | 1996 |
The effect of temperature on the discomfort caused by topical local anaesthesia.
Topics: Aged; Anesthetics, Local; Humans; Lidocaine; Middle Aged; Pain; Pain Measurement; Procaine; Temperat | 1995 |
The application of EMLA and glyceryl trinitrate ointment prior to venepuncture.
Topics: Adult; Anesthetics, Local; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; | 1996 |
Botulinum toxin is unsatisfactory therapy for fibromyalgia.
Topics: Botulinum Toxins; Double-Blind Method; Female; Fibromyalgia; Humans; Injections, Intramuscular; Lido | 1996 |
[Skillfulness is essential to improve venipuncture pain in combination with lidocaine containing adhesive tape].
Topics: Administration, Topical; Adult; Aged; Clinical Competence; Dosage Forms; Female; Humans; Lidocaine; | 1996 |
Investigation of bioequivalence and tolerability of intramuscular ceftriaxone injections by using 1% lidocaine, buffered lidocaine, and sterile water diluents.
Topics: Adult; Buffers; Ceftriaxone; Cephalosporins; Chemistry, Pharmaceutical; Female; Humans; Injections, | 1996 |
Computer-controlled lidocaine infusion for the evaluation of neuropathic pain after peripheral nerve injury.
Topics: Adult; Aged; Computers; Humans; Infusion Pumps; Lidocaine; Middle Aged; Pain; Pain Measurement; Pain | 1996 |
Alfentanil-mediated analgesia during propofol injection: no evidence for a peripheral action.
Topics: Adolescent; Adult; Aged; Alfentanil; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Loca | 1996 |
The use of pH adjusted lignocaine in controlling operative pain in the day surgery unit: a prospective, randomised trial.
Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Anesthetics, Local; Buffers; Child; Double-Blind | 1996 |
Injection pain with propofol. Reduction with aspiration of blood.
Topics: Adult; Anesthetics, Intravenous; Female; Humans; Injections, Intravenous; Lidocaine; Male; Pain; Phl | 1996 |
The effect of pretreatment with ketorolac on pain during intravenous injection of propofol.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Anesthetics, Intravenous; Double-Blind Method; Fe | 1996 |
Hyaluronidase (Hyalase): a useful addition in haematoma block?
Topics: Anesthetics, Local; Double-Blind Method; Drug Combinations; Humans; Hyaluronoglucosaminidase; Lidoca | 1996 |
Alkalinisation of lignocaine to reduce the pain of digital nerve blockade.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Chemistry, Pharmaceutical; Double-Bl | 1996 |
A similar incidence of transient neurologic symptoms after spinal anesthesia with 2% and 5% lidocaine.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Female; Genitalia, Female; Humans; Incidence; Lidocai | 1996 |
[Comparison of analgesic effect of lidocaine tape versus eutectic mixture of lidocaine and tetracaine during infiltration of local anesthetics before epidural block].
Topics: Administration, Topical; Adult; Anesthesia, Epidural; Anesthesia, Local; Anesthetics, Combined; Anes | 1996 |
The combination of morphine with local anaesthetic in rhinoplasty--no evidence of a peripheral morphine effect.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Double-Blind Method; Female; Humans; Injections; Intr | 1996 |
Comparison of 0.5% and 1.0% lidocaine for abortions.
Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Double-Blind Meth | 1996 |
Preventing pain during injection of propofol: the optimal dose of lidocaine.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Catheterization, Peripheral; Double-Blind Metho | 1996 |
Topical application of lidocaine-prilocaine (EMLA) cream reduces the pain of intramuscular infiltration of saline solution.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Injection | 1996 |
Topical tetracaine attenuates the pain of infiltration of buffered lidocaine.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; | 1996 |
Subcutaneous lidocaine does not affect the success rate of intravenous access in children less than 24 months of age.
Topics: Anesthetics, Local; Catheterization, Peripheral; Humans; Infant; Injections, Subcutaneous; Lidocaine | 1996 |
Analgesia for venepuncture in a paediatric surgery centre.
Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthetics, Local; Chi | 1995 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Efficacy of injections of corticosteroids for subacromial impingement syndrome.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; | 1996 |
Analgesic efficacy and safety of an intraoral lidocaine patch.
Topics: Administration, Topical; Adolescent; Adult; Aged; Analysis of Variance; Anesthesia, Dental; Anesthes | 1996 |
EMLA cream as a topical anesthetic before office phlebotomy in children.
Topics: Adolescent; Ambulatory Care; Anesthetics, Local; Anxiety; Child; Child, Preschool; Double-Blind Meth | 1996 |
A comparison of topical anaesthesia and electronic nerve stimulation for reducing the pain of intra-oral injections.
Topics: Administration, Buccal; Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Local; Chi-Squ | 1996 |
Randomized, prospective, double-blind study of the effects on pain perception of lidocaine jelly versus plain lubricant during outpatient rigid cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthetics, Local; Cystoscopes; Cystoscopy; Dosage | 1997 |
Randomized, prospective, double-blind study of the effects on pain perception of lidocaine jelly versus plain lubricant during outpatient rigid cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthetics, Local; Cystoscopes; Cystoscopy; Dosage | 1997 |
Randomized, prospective, double-blind study of the effects on pain perception of lidocaine jelly versus plain lubricant during outpatient rigid cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthetics, Local; Cystoscopes; Cystoscopy; Dosage | 1997 |
Randomized, prospective, double-blind study of the effects on pain perception of lidocaine jelly versus plain lubricant during outpatient rigid cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthetics, Local; Cystoscopes; Cystoscopy; Dosage | 1997 |
Warming lignocaine reduces the pain of injection during local anaesthetic eyelid surgery.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Chalazion; Double-Blind Method; Female; Hot Temperature | 1996 |
Reduction of propofol pain--fentanyl vs lidocaine.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Female; F | 1996 |
Pain elicited during intraoral infiltration with buffered lidocaine.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Local; Buffers; Cross-Over Studies; Do | 1996 |
EMLA cream for pain reduction in diagnostic allergy skin testing: effects on wheal and flare responses.
Topics: Adult; Allergens; Anesthetics, Local; Drug Combinations; Female; Humans; Lidocaine; Lidocaine, Prilo | 1997 |
Tetracaine versus lidocaine-prilocaine for preventing venipuncture-induced pain in children.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Dosage Forms; Drug | 1997 |
Effect of neonatal circumcision on pain response during subsequent routine vaccination.
Topics: Analysis of Variance; Anesthetics, Local; Circumcision, Male; Cohort Studies; Drug Combinations; Hum | 1997 |
Lidocaine tape relieves pain due to needle insertion during stellate ganglion block.
Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Female; Humans; Lidocaine; Male; Middle Aged | 1997 |
The antinociceptive effect of epidural lignocaine and fentanyl during lithotripsy.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Dose-Response Relationship, Drug; Doubl | 1997 |
Effects of topical nitroglycerin and intravenous lidocaine on propofol-induced pain on injection.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Double-Blind Method; Female; Humans; Injec | 1997 |
A comparison of three regional anaesthesia techniques for outpatient knee arthroscopy.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Loca | 1997 |
Efficacy and safety of lidocaine-prilocaine cream for pain during circumcision.
Topics: Anesthesia, Local; Anesthetics, Local; Circumcision, Male; Crying; Double-Blind Method; Drug Combina | 1997 |
Patient comfort during cataract surgery with modified topical and peribulbar anesthesia.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Bupi | 1997 |
[Premixing lidocaine reduces the incidence and severity of pain on injection of propofol].
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; Humans; Inje | 1997 |
Neonatal circumcision.
Topics: Anesthetics, Local; Circumcision, Male; Drug Combinations; Humans; Hypnotics and Sedatives; Infant, | 1997 |
Effect of percutaneous local anaesthetics on pain reduction during pulse dye laser treatment of portwine stains.
Topics: Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Drug Combinations; Hu | 1997 |
Quantitative assessment of differential sensory blockade after lumbar epidural lidocaine.
Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Chronic Disease; Cold Temperature; Electric Stimula | 1997 |
Comparison of physiotherapy, manipulation, and corticosteroid injection for treating shoulder complaints in general practice: randomised, single blind study.
Topics: Anesthetics, Local; Drug Combinations; Family Practice; Follow-Up Studies; Glucocorticoids; Humans; | 1997 |
[Effect of lidocaine administration mode on decreasing injection pain caused by propofol].
Topics: Anesthetics, Intravenous; Anesthetics, Local; Humans; Injections, Intravenous; Lidocaine; Pain; Pain | 1997 |
Effect of lignocaine and pH on propofol-induced pain.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Chemistry, Pharmaceutical; Do | 1997 |
[Efficacy of lidocaine tape for venous cannulation in children].
Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Catheterization, Peripheral; Child; Child | 1997 |
Comparative topical anaesthesia of EMLA and liposome-encapsulated tetracaine.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Drug Ca | 1997 |
Beyond dorsal penile nerve block: a more humane circumcision.
Topics: Circumcision, Male; Double-Blind Method; Humans; Hydrocortisone; Infant Behavior; Infant Care; Infan | 1997 |
A prospective, randomized, double-blind study comparing lignocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy.
Topics: Analgesia; Anesthetics, Local; Cystoscopy; Double-Blind Method; Female; Gels; Humans; Lidocaine; Lub | 1997 |
Fibromyalgia--are there different mechanisms in the processing of pain? A double blind crossover comparison of analgesic drugs.
Topics: Adult; Anesthetics, Dissociative; Area Under Curve; Cross-Over Studies; Double-Blind Method; Drug Th | 1997 |
Topical lidocaine adrenaline tetracaine (LAT gel) versus injectable buffered lidocaine for local anesthesia in laceration repair.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Combined; Anesthetics, Local; Child; Child, | 1997 |
Effectiveness of lidocaine hydrochloride on venipuncture sites.
Topics: Anesthetics, Local; Double-Blind Method; Humans; Injections, Intradermal; Lidocaine; Pain; Phlebotom | 1997 |
Pretreatment with topical 60% lidocaine tape reduces pain on injection of propofol.
Topics: Administration, Cutaneous; Adult; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Loca | 1997 |
Prilocaine/lidocaine patch as a local premedication for skin biopsy in children.
Topics: Administration, Cutaneous; Adolescent; Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; Ch | 1997 |
[Influence of preanesthetic medication on the effect of a local anesthetic tape].
Topics: Adjuvants, Anesthesia; Administration, Topical; Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents | 1997 |
New non-cocaine-containing topical anesthetics compared with tetracaine-adrenaline-cocaine during repair of lacerations.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; C | 1997 |
Sustained relief of oral aphthous ulcer pain from topical diclofenac in hyaluronan: a randomized, double-blind clinical trial.
Topics: Administration, Topical; Adolescent; Adult; Analgesics; Analysis of Variance; Anesthetics, Local; An | 1997 |
Topical anaesthesia in haemodialysis: evaluation of topical anaesthesia with lidocaine during vascular access in children undergoing long-term haemodialysis for chronic renal failure.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Catheters, Indwelling; Child; Double-Blind | 1997 |
Isometric abduction muscle activation in patients with rotator tendinosis of the shoulder.
Topics: Adult; Anesthetics, Local; Bupivacaine; Chronic Disease; Electromyography; Female; Humans; Isometric | 1997 |
Use of eutectic mixture of local anesthetics: an effective topical anesthetic for slit-smear testing of patients with Hansen's disease.
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Biopsy; Ear, External; Elbow; Female; Humans; Knee | 1997 |
[The optimum time interval for applying lidocaine containing adhesive tape is 6 to 8 hours for venipuncture pain relief].
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Dosage Forms; Humans; Lidocain | 1997 |
The efficacy of an injection of steroids for medial epicondylitis. A prospective study of sixty elbows.
Topics: Adult; Age Factors; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Ster | 1997 |
Local anesthesia for fine-needle aspiration biopsy of palpable breast masses: the effectiveness of a jet injection system.
Topics: Adult; Anesthesia, Local; Biopsy, Needle; Breast Diseases; Ethyl Chloride; Female; Humans; Injection | 1997 |
[Combined treatment for adhesive capsulitis of the shoulder].
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Bursitis; Combined Modal | 1997 |
Two modalities of topical anesthesia for office hysteroscopy.
Topics: Anesthesia, Local; Anesthetics, Local; Female; Humans; Hysteroscopy; Lidocaine; Pain; Prilocaine | 1997 |
Pain of local anesthetics: rate of administration and buffering.
Topics: Adult; Buffers; Female; Humans; Injections, Intradermal; Injections, Subcutaneous; Lidocaine; Male; | 1998 |
An evaluation of intraoral lidocaine patches in reducing needle-insertion pain.
Topics: Administration, Topical; Adolescent; Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, L | 1997 |
The analgesic effect of fentanyl, morphine, meperidine, and lidocaine in the peripheral veins: a comparative study.
Topics: Adult; Analgesics; Double-Blind Method; Female; Fentanyl; Humans; Injections, Intravenous; Lidocaine | 1998 |
The effects of hyaluronidase on the efficacy and on the pain of administration of 1% lidocaine.
Topics: Adolescent; Adult; Anesthetics, Local; Double-Blind Method; Humans; Hyaluronoglucosaminidase; Hydrog | 1998 |
[Effectiveness of local anesthesia using EMLA cream for laser treatment of cervical and vulvar lesions].
Topics: Anesthetics, Combined; Anesthetics, Local; Condylomata Acuminata; Female; Humans; Laser Therapy; Lid | 1997 |
Topical anaesthesia in neonatal circumcision: a study of 208 consecutive cases.
Topics: Administration, Topical; Age Factors; Anesthetics, Local; Australia; Child, Preschool; Circumcision, | 1996 |
The effect of order on pain of local anesthetic infiltration.
Topics: Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Buffers; Double-Blind Method; Female; Huma | 1998 |
Clinical comparison of preinjection anesthetics.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Atmosphere; Child | 1998 |
Pain on injection of propofol. A comparison of cold propofol with propofol premixed with lignocaine.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Cold Temperature; Double-Blin | 1998 |
Analgesia for neonatal circumcision: a randomized controlled trial of EMLA cream versus dorsal penile nerve block.
Topics: Anesthesia, Local; Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidoc | 1998 |
Subcutaneous erythropoietin alpha (Eprex) is more painful than erythropoietin beta (Recormon)
Topics: Adult; Anesthetics, Local; Child; Drug Compounding; Erythropoietin; Female; Humans; Injections, Subc | 1998 |
Comparison of intravenous retention of fentanyl and lidocaine on local analgesia in propofol injection pain.
Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local | 1997 |
Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery.
Topics: Aged; Alprazolam; Anesthesia, Local; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Bromazepam; B | 1998 |
[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination].
Topics: Adjuvants, Anesthesia; Administration, Rectal; Anesthesia, Local; Anesthetics, Inhalation; Anestheti | 1998 |
Ring block for neonatal circumcision.
Topics: Anesthetics, Local; Circumcision, Male; Crying; Humans; Infant, Newborn; Lidocaine; Male; Nerve Bloc | 1998 |
Comparison of the effect of EMLA and semicircular subcutaneous anaesthesia in the prevention of tourniquet pain during plexus block anaesthesia of the arm.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Brachial Plexus; Bupivacaine; Female; Forearm; H | 1998 |
Emla cream as a local anaesthetic in MMR vaccination.
Topics: Anesthetics, Local; Child; Double-Blind Method; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combin | 1998 |
Prospective evaluation of topical versus retrobulbar anesthesia: a converting surgeon's experience.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; Anesthet | 1998 |
Lidocaine-prilocaine cream (EMLA Cream) as a topical anaesthetic for the cleansing of leg ulcers. The effect of length of application time.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Combined; Debridement; Drug Administr | 1998 |
Lidocaine-prilocaine cream (EMLA Cream) as a topical anaesthetic for the cleansing of leg ulcers. The effect of length of application time.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Combined; Debridement; Drug Administr | 1998 |
Lidocaine-prilocaine cream (EMLA Cream) as a topical anaesthetic for the cleansing of leg ulcers. The effect of length of application time.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Combined; Debridement; Drug Administr | 1998 |
Lidocaine-prilocaine cream (EMLA Cream) as a topical anaesthetic for the cleansing of leg ulcers. The effect of length of application time.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Combined; Debridement; Drug Administr | 1998 |
Pain reduction in lidocaine administration through buffering and warming.
Topics: Adult; Anesthetics, Local; Buffers; Double-Blind Method; Hot Temperature; Humans; Injections, Intrad | 1998 |
Repetitive pinching of the skin during lidocaine infiltration reduces patient discomfort.
Topics: Age Factors; Aged; Analysis of Variance; Anesthetics, Local; Carcinoma; Confounding Factors, Epidemi | 1998 |
Transient radicular irritation after spinal anesthesia induced with hyperbaric solutions of cerebrospinal fluid-diluted lidocaine 50 mg/ml or mepivacaine 40 mg/ml or bupivacaine 5 mg/ml.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Back Pain; Bupivacaine; Cere | 1998 |
Topical lidocaine-prilocaine cream (EMLA) versus local infiltration anesthesia for radial artery cannulation.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Female; Humans; Inj | 1998 |
[Pain-free injection of propofol].
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Female; Fentanyl; Humans; Hypothermia, Induced; | 1998 |
[Sixty percent lidocaine tape alleviates pain on injection of propofol after diminishing venipuncture pain].
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Bandages; Female; Humans; Injections, Intraveno | 1998 |
Alleviation of the pain of venepuncture in neonates.
Topics: Anesthetics, Local; Double-Blind Method; Female; Humans; Infant, Newborn; Lidocaine; Lidocaine, Pril | 1998 |
[Reduction of pain on injection of propofol: a comparison of fentanyl with lidocaine].
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Drug Combinations; Fe | 1998 |
The ability of lumbar medial branch blocks to anesthetize the zygapophysial joint. A physiologic challenge.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Animals; Female; Humans; Joints; Lidocaine; Lumbar Ve | 1998 |
Sex differences in response to cutaneous anesthesia: a double blind randomized study.
Topics: Adolescent; Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Male; Pain; P | 1998 |
Randomised control trial of pH buffered lignocaine with adrenaline in outpatient operations.
Topics: Adrenergic Agonists; Ambulatory Surgical Procedures; Anesthetics, Local; Buffers; Cross-Over Studies | 1998 |
Pain following intravenous administration of sedative agents: a comparison of propofol with three benzodiazepines.
Topics: Adult; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Anti-Anxiety Agents; Cros | 1998 |
Lidocaine as a diluent for administration of benzathine penicillin G.
Topics: Adolescent; Anesthetics, Local; Antibiotic Prophylaxis; Child; Cross-Over Studies; Double-Blind Meth | 1998 |
A randomized clinical trial of combined topical-intracameral anesthesia in cataract surgery.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Ante | 1998 |
Subcutaneous administration of midazolam: a comparison of the Bioject jet injector with the conventional syringe and needle.
Topics: Adolescent; Adult; Anesthetics, Local; Double-Blind Method; Equipment Design; Humans; Hypnotics and | 1998 |
A blinded, randomized, paired, placebo-controlled trial of 20-minute EMLA cream to reduce the pain of peripheral i.v. cannulation in the ED.
Topics: Anesthetics, Combined; Anesthetics, Local; Catheterization, Peripheral; Emergency Service, Hospital; | 1998 |
Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia.
Topics: Adult; Anesthetics, Local; Benzyl Alcohol; Diphenhydramine; Double-Blind Method; Drug Combinations; | 1998 |
Cutaneous tape stripping to accelerate the anesthetic effects of EMLA cream: a randomized, controlled trial.
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Catheterization, Peripheral; Female; Humans; Lidoc | 1998 |
Pain in scleral pocket incision cataract surgery using topical and peribulbar anesthesia.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; A | 1998 |
Use of topical lidocaine in pediatric laceration repair: a review of topical anesthetics.
Topics: Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Emergency Servi | 1998 |
A comparison of patient comfort during cataract surgery with topical anesthesia versus topical anesthesia and intracameral lidocaine.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Animals; An | 1999 |
Randomised double blind trial of EMLA for the control of pain related to cryotherapy in the treatment of genital HPV lesions.
Topics: Adolescent; Adult; Anesthetics, Combined; Anesthetics, Local; Cryotherapy; Double-Blind Method; Fema | 1998 |
Pain on injection of propofol: the mitigating influence of metoclopramide using different techniques.
Topics: Adult; Analgesics; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Chi-Square Di | 1999 |
Dilution of spinal lidocaine does not alter the incidence of transient neurologic symptoms.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Female; Humans; Injections, Spinal; Lidocaine; Male; | 1999 |
EMLA cream as a topical anesthetic for the repeated mechanical debridement of venous leg ulcers: a double-blind, placebo-controlled study.
Topics: Administration, Cutaneous; Aged; Anesthetics, Local; Debridement; Double-Blind Method; Female; Human | 1999 |
EMLA cream as a topical anesthetic for the repeated mechanical debridement of venous leg ulcers: a double-blind, placebo-controlled study.
Topics: Administration, Cutaneous; Aged; Anesthetics, Local; Debridement; Double-Blind Method; Female; Human | 1999 |
EMLA cream as a topical anesthetic for the repeated mechanical debridement of venous leg ulcers: a double-blind, placebo-controlled study.
Topics: Administration, Cutaneous; Aged; Anesthetics, Local; Debridement; Double-Blind Method; Female; Human | 1999 |
EMLA cream as a topical anesthetic for the repeated mechanical debridement of venous leg ulcers: a double-blind, placebo-controlled study.
Topics: Administration, Cutaneous; Aged; Anesthetics, Local; Debridement; Double-Blind Method; Female; Human | 1999 |
Evaluation of lidocaine as an analgesic when added to hypertonic saline for sclerotherapy.
Topics: Analgesics; Anesthetics, Local; Double-Blind Method; Follow-Up Studies; Humans; Incidence; Injection | 1999 |
Plain and buffered lidocaine for neonatal circumcision.
Topics: Anesthetics, Local; Autonomic Nerve Block; Buffers; Circumcision, Male; Humans; Infant, Newborn; Int | 1999 |
[Local digital anesthesia using lidocaine with or without bicarbonate. A comparative randomized study].
Topics: Adult; Alkalies; Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Local; Bicarbonates | 1998 |
EMLA patch for spinal puncture. A comparison of EMLA patch with lignocaine infiltration and placebo patch.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anestheti | 1998 |
EMLA patch for spinal puncture. A comparison of EMLA patch with lignocaine infiltration and placebo patch.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anestheti | 1998 |
EMLA patch for spinal puncture. A comparison of EMLA patch with lignocaine infiltration and placebo patch.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anestheti | 1998 |
EMLA patch for spinal puncture. A comparison of EMLA patch with lignocaine infiltration and placebo patch.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anestheti | 1998 |
EMLA patch for spinal puncture. A comparison of EMLA patch with lignocaine infiltration and placebo patch.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anestheti | 1998 |
EMLA patch for spinal puncture. A comparison of EMLA patch with lignocaine infiltration and placebo patch.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anestheti | 1998 |
EMLA patch for spinal puncture. A comparison of EMLA patch with lignocaine infiltration and placebo patch.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anestheti | 1998 |
EMLA patch for spinal puncture. A comparison of EMLA patch with lignocaine infiltration and placebo patch.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anestheti | 1998 |
EMLA patch for spinal puncture. A comparison of EMLA patch with lignocaine infiltration and placebo patch.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anestheti | 1998 |
The use of lidocaine for preventing the withdrawal associated with the injection of rocuronium in children and adolescents.
Topics: Adolescent; Androstanols; Child; Child, Preschool; Humans; Lidocaine; Movement; Neuromuscular Nondep | 1999 |
Positive symptoms in multiple sclerosis: their treatment with sodium channel blockers, lidocaine and mexiletine.
Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Lidocaine; Male; Mexiletine; Middle Aged; M | 1999 |
Subcutaneous infusion of lidocaine provides effective pain relief for CRPS patients.
Topics: Adult; Anesthetics, Local; Female; Humans; Infusion Pumps; Injections, Subcutaneous; Lidocaine; Male | 1999 |
[Efficacy of EMLA cream, effect of time and place of application].
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Double-Blind Method; Elbow; Emulsions; Erythema; F | 1999 |
Prospective, randomized comparison of epidural versus parenteral opioid analgesia in thoracic trauma.
Topics: Adolescent; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Cytokines | 1999 |
Prospective, randomized comparison of epidural versus parenteral opioid analgesia in thoracic trauma.
Topics: Adolescent; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Cytokines | 1999 |
Prospective, randomized comparison of epidural versus parenteral opioid analgesia in thoracic trauma.
Topics: Adolescent; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Cytokines | 1999 |
Prospective, randomized comparison of epidural versus parenteral opioid analgesia in thoracic trauma.
Topics: Adolescent; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Cytokines | 1999 |
Intraperitoneal lidocaine decreases intraoperative pain during postpartum tubal ligation.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Injections, Intraperitoneal; Intraop | 1999 |
Effects of single and repeated applications of a eutectic mixture of local anaesthetics (EMLA) cream on spontaneous and evoked pain in post-herpetic neuralgia.
Topics: Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Female; Herpesviridae Infections | 1999 |
Efficacy of parental application of eutectic mixture of local anesthetics for intravenous insertion.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Anxiety; Child; Child, Preschool; Female; Humans; | 1999 |
Adding clonidine to lidocaine for intravenous regional anesthesia prevents tourniquet pain.
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Loca | 1999 |
The rectal administration of lidocaine gel and tolerance of transrectal ultrasonography-guided biopsy of the prostate: a prospective randomized placebo-controlled study.
Topics: Administration, Rectal; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Biopsy; Gels | 1999 |
Petroleum jelly is an ideal contact medium for pain reduction and successful treatment with extracorporeal shock wave lithotripsy.
Topics: Anesthetics, Local; Emollients; Gels; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Lit | 1999 |
Painless intravenous catheterization by intradermal jet injection of lidocaine: a randomized trial.
Topics: Administration, Cutaneous; Adult; Aged; Anesthetics, Local; Catheterization; Female; Humans; Injecti | 1999 |
A trial of intravenous lidocaine on the pain and allodynia of postherpetic neuralgia.
Topics: Aged; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female; Herpesviridae Infections; | 1999 |
Does local anaesthetic affect the success rate of intravenous cannulation?
Topics: Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Female; Humans; Injections, Intr | 1999 |
The effects of EMLA and a topical formulation of 4% amethocaine (Ametop) on pain associated with retrobulbar injection.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Cataract Extraction; Female; Humans; | 1999 |
Iontophoretically applied lidocaine reduces pain on propofol injection.
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; Humans; Iont | 1999 |
Relative efficacy of amethocaine gel and lidocaine-prilocaine cream for Port-a-Cath puncture in children.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Catheterization, Central Venous; Catheters, Indwe | 1999 |
Relative efficacy of amethocaine gel and lidocaine-prilocaine cream for Port-a-Cath puncture in children.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Catheterization, Central Venous; Catheters, Indwe | 1999 |
Relative efficacy of amethocaine gel and lidocaine-prilocaine cream for Port-a-Cath puncture in children.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Catheterization, Central Venous; Catheters, Indwe | 1999 |
Relative efficacy of amethocaine gel and lidocaine-prilocaine cream for Port-a-Cath puncture in children.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Catheterization, Central Venous; Catheters, Indwe | 1999 |
Propofol-thiopentone admixture-hypnotic dose, pain on injection and effect on blood pressure.
Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Intravenous; | 1999 |
The optimal effective concentration of lidocaine to reduce pain on injection of propofol.
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Dilatation and Curettage; Double-Blind Me | 1999 |
Peribulbar anesthesia with either 0.75% ropivacaine or a 2% lidocaine and 0.5% bupivacaine mixture for vitreoretinal surgery: a double-blinded study.
Topics: Amides; Anesthesia, Conduction; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Double-Blind | 1999 |
Management of pain from heel lance with lidocaine-prilocaine (EMLA) cream: is it safe and efficacious in preterm infants?
Topics: Anesthetics, Combined; Anesthetics, Local; Heel; Humans; Infant, Newborn; Infant, Premature; Lidocai | 1999 |
[Premixing of 5% dextrose in Ringer's acetate solution with propofol reduces incidence and severity of pain on propofol injection].
Topics: Adult; Aged; Anesthesia, General; Double-Blind Method; Female; Glucose; Humans; Injections, Intraven | 1999 |
Intradermal bacteriostatic 0.9% sodium chloride containing the preservative benzyl alcohol compared with intradermal lidocaine hydrochloride 1% for attenuation of intravenous cannulation pain.
Topics: Adult; Aged; Anesthetics, Local; Benzyl Alcohol; Catheterization, Peripheral; Female; Humans; Inject | 1998 |
Analgesia during extracorporeal shock wave lithotripsy using the Medstone STS lithotriptor: a randomized prospective study.
Topics: Adult; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory | 1999 |
[Is local anesthesia necessary for spinal needle insertion?].
Topics: Adult; Aged; Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Local; Female; Humans; Injections, | 1999 |
The effect of differential and complete nerve block on experimental muscle pain in humans.
Topics: Adult; Anesthetics, Local; Electric Stimulation; Female; Humans; Hypertonic Solutions; Injections, I | 1999 |
[Administration of propofol. Addition of lidocaine eases the pain].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Anesthetics, Local; Drug Combi | 1999 |
Comparison of lignocaine-prilocaine cream and amethocaine gel for local analgesia before venepuncture in children.
Topics: Adolescent; Analgesia; Anesthetics, Combined; Anesthetics, Local; Anxiety; Child; Child, Preschool; | 1999 |
Steroid injection for heel pain: evidence of short-term effectiveness. A randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Fasciitis; Female; Foot Dis | 1999 |
Steroid injection for heel pain: evidence of short-term effectiveness. A randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Fasciitis; Female; Foot Dis | 1999 |
Steroid injection for heel pain: evidence of short-term effectiveness. A randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Fasciitis; Female; Foot Dis | 1999 |
Steroid injection for heel pain: evidence of short-term effectiveness. A randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Fasciitis; Female; Foot Dis | 1999 |
A prospective, randomized, double-blind and placebo-controlled study to assess the efficacy of paracervical block in the pain relief during egg collection in IVF.
Topics: Abdominal Pain; Analgesia; Anesthetics, Local; Double-Blind Method; Female; Fertilization in Vitro; | 1999 |
A prospective, randomized, double-blind and placebo-controlled study to assess the efficacy of paracervical block in the pain relief during egg collection in IVF.
Topics: Abdominal Pain; Analgesia; Anesthetics, Local; Double-Blind Method; Female; Fertilization in Vitro; | 1999 |
A prospective, randomized, double-blind and placebo-controlled study to assess the efficacy of paracervical block in the pain relief during egg collection in IVF.
Topics: Abdominal Pain; Analgesia; Anesthetics, Local; Double-Blind Method; Female; Fertilization in Vitro; | 1999 |
A prospective, randomized, double-blind and placebo-controlled study to assess the efficacy of paracervical block in the pain relief during egg collection in IVF.
Topics: Abdominal Pain; Analgesia; Anesthetics, Local; Double-Blind Method; Female; Fertilization in Vitro; | 1999 |
A prospective, randomized, double-blind and placebo-controlled study to assess the efficacy of paracervical block in the pain relief during egg collection in IVF.
Topics: Abdominal Pain; Analgesia; Anesthetics, Local; Double-Blind Method; Female; Fertilization in Vitro; | 1999 |
A prospective, randomized, double-blind and placebo-controlled study to assess the efficacy of paracervical block in the pain relief during egg collection in IVF.
Topics: Abdominal Pain; Analgesia; Anesthetics, Local; Double-Blind Method; Female; Fertilization in Vitro; | 1999 |
A prospective, randomized, double-blind and placebo-controlled study to assess the efficacy of paracervical block in the pain relief during egg collection in IVF.
Topics: Abdominal Pain; Analgesia; Anesthetics, Local; Double-Blind Method; Female; Fertilization in Vitro; | 1999 |
A prospective, randomized, double-blind and placebo-controlled study to assess the efficacy of paracervical block in the pain relief during egg collection in IVF.
Topics: Abdominal Pain; Analgesia; Anesthetics, Local; Double-Blind Method; Female; Fertilization in Vitro; | 1999 |
A prospective, randomized, double-blind and placebo-controlled study to assess the efficacy of paracervical block in the pain relief during egg collection in IVF.
Topics: Abdominal Pain; Analgesia; Anesthetics, Local; Double-Blind Method; Female; Fertilization in Vitro; | 1999 |
Topical anesthesia for office hysteroscopy. A prospective, randomized study comparing two modalities.
Topics: Adult; Anesthetics, Local; Female; Humans; Hysteroscopes; Hysteroscopy; Lidocaine; Middle Aged; Offi | 1999 |
Topical anesthesia for office hysteroscopy. A prospective, randomized study comparing two modalities.
Topics: Adult; Anesthetics, Local; Female; Humans; Hysteroscopes; Hysteroscopy; Lidocaine; Middle Aged; Offi | 1999 |
Topical anesthesia for office hysteroscopy. A prospective, randomized study comparing two modalities.
Topics: Adult; Anesthetics, Local; Female; Humans; Hysteroscopes; Hysteroscopy; Lidocaine; Middle Aged; Offi | 1999 |
Topical anesthesia for office hysteroscopy. A prospective, randomized study comparing two modalities.
Topics: Adult; Anesthetics, Local; Female; Humans; Hysteroscopes; Hysteroscopy; Lidocaine; Middle Aged; Offi | 1999 |
Efficacy of supplementary intracameral lidocaine in routine phacoemulsification under topical anesthesia.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Anterior Cham | 1999 |
To determine whether the temperature of 2% lignocaine gel affects the initial discomfort which may be associated with its instillation into the male urethra.
Topics: Administration, Topical; Anesthetics, Local; Double-Blind Method; Gels; Humans; Lidocaine; Male; Mid | 1999 |
A novel mechanism for benign essential blepharospasm.
Topics: Anesthetics, Local; Autonomic Nerve Block; Autonomic Nervous System Diseases; Blepharospasm; Eyelids | 1999 |
A randomized, controlled trial of a eutectic mixture of local anesthetic cream (lidocaine and prilocaine) versus penile nerve block for pain relief during circumcision.
Topics: Administration, Cutaneous; Anesthetics, Combined; Anesthetics, Local; Circumcision, Male; Double-Bli | 1999 |
Alkalinizing local anesthetic does not decrease pain during injection for dorsal penile nerve block.
Topics: Adolescent; Adult; Alkalies; Analysis of Variance; Anesthetics, Local; Buffers; Bupivacaine; Circumc | 1999 |
The efficacy of EMLA versus ELA-Max for pain relief in medium-depth chemical peeling: a clinical and histopathologic evaluation.
Topics: Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; Chemexfoliation; Female; Glycolates; Huma | 2000 |
Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II.
Topics: Adult; Aged; Anesthetics, Local; Blood Pressure; Cold Temperature; Complex Regional Pain Syndromes; | 2000 |
A randomized controlled trial of intracameral lidocaine during phacoemulsification under topical anesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Anterior Chamber; Capsulorhex | 2000 |
A potential mechanism of propofol-induced pain on injection based on studies using nafamostat mesilate.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Anesthetics, Local; Benzamidin | 1999 |
Computer-assisted infrared thermographic study of axon reflex induced by intradermal melittin.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Axons; Diagnosis, Computer-Assisted; Femal | 2000 |
Towards a pain-free venepuncture.
Topics: Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Humans; Lidocaine; Pain; Pain Me | 2000 |
Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle A | 2000 |
Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle A | 2000 |
Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle A | 2000 |
Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle A | 2000 |
Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle A | 2000 |
Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle A | 2000 |
Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle A | 2000 |
Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle A | 2000 |
Intravenous lidocaine in central pain: a double-blind, placebo-controlled, psychophysical study.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle A | 2000 |
Effects of 3 analgesic regimens on the perception of pain after removal of femoral artery sheaths.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Angioplasty, Balloon, Coronary; Attitude to Hea | 2000 |
Anesthetic efficacy of intrauterine lidocaine for endometrial biopsy: a randomized double-masked trial.
Topics: Administration, Intravaginal; Anesthetics, Local; Biopsy; Double-Blind Method; Endometrium; Female; | 2000 |
Propofol and pain on induction: the effect of injectate temperature in children.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Chi-Square Distribution; Child; Child, Preschool; Cold | 2000 |
Pain on injection of rocuronium: influence of two doses of lidocaine pretreatment.
Topics: Adolescent; Adult; Androstanols; Anesthetics, Local; Dose-Response Relationship, Drug; Double-Blind | 2000 |
Premixed buffered lidocaine retains efficacy after prolonged room temperature storage.
Topics: Anesthetics, Local; Buffers; Chemistry, Pharmaceutical; Double-Blind Method; Drug Combinations; Drug | 2000 |
Both EMLA and placebo cream reduced pain during extracorporeal piezoelectric shock wave lithotripsy with the Piezolith 2300.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female; Human | 2000 |
A randomised study of lidocaine and prilocaine for spinal anaesthesia.
Topics: Adult; Aged; Anesthesia, Spinal; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; P | 2000 |
The use of EMLA reduces the pain associated with digital ring block for ingrowing toenail correction.
Topics: Adolescent; Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Lidocaine, Pr | 2000 |
[Use of the anesthetic cream EMLA in arterial punction].
Topics: Anesthesia, Local; Anesthetics, Local; Arteries; Blood Specimen Collection; Double-Blind Method; Fem | 2000 |
The effect of local anaesthetic spray on the pain associated with local anaesthetic injection, prior to biopsy or loop diathermy to the cervix in the outpatient colposcopy clinic.
Topics: Adult; Ambulatory Care; Anesthetics, Local; Colposcopy; Double-Blind Method; Female; Humans; Injecti | 2000 |
Does preservative-free lignocaine 1% for hydrodissection reduce pain during phacoemulsification?
Topics: Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Humans; Isotonic Solutions; Lidocaine; O | 2000 |
Lidocaine-prilocaine patch decreases the pain associated with the subcutaneous administration of measles-mumps-rubella vaccine but does not adversely affect the antibody response.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Antibodies; Double-Blind Method; | 2000 |
Combined analgesia and local anesthesia to minimize pain during circumcision.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analysis of Variance; Anesthesia, Local; Anesthe | 2000 |
Topical anesthesia without intracameral lidocaine in cataract surgery.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Blepharospasm; Cataract Extraction; Humans; Hypnotics a | 2000 |
Evaluation of prilocaine for the reduction of pain associated with transmucosal anesthetic administration.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; In | 1999 |
Stepwise pain score analysis of the effect of local lignocaine on outpatient hysteroscopy: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Ambulatory Care; Anesthetics, Local; Cervix Uteri; Double-Blind Method; Female; Gels; Humans; | 2000 |
Comparison of 4 analgesic agents for venipuncture.
Topics: Adolescent; Adult; Aerosols; Aged; Aged, 80 and over; Anesthetics, Local; Chlorofluorocarbons; Chlor | 2000 |
Comparison of 4 analgesic agents for venipuncture.
Topics: Adolescent; Adult; Aerosols; Aged; Aged, 80 and over; Anesthetics, Local; Chlorofluorocarbons; Chlor | 2000 |
Comparison of 4 analgesic agents for venipuncture.
Topics: Adolescent; Adult; Aerosols; Aged; Aged, 80 and over; Anesthetics, Local; Chlorofluorocarbons; Chlor | 2000 |
Comparison of 4 analgesic agents for venipuncture.
Topics: Adolescent; Adult; Aerosols; Aged; Aged, 80 and over; Anesthetics, Local; Chlorofluorocarbons; Chlor | 2000 |
Induction pain perception after premedication with propofol vs lidocaine: a pilot study.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Female; Humans; Infusions, Intravenous; Intubation, In | 2000 |
[Intravenous lignocaine for chronic pain: an 18-month experience].
Topics: Adult; Aged; Anesthetics, Local; Blood Pressure; Chronic Disease; Female; Heart Rate; Humans; Infusi | 1998 |
Pain perception with pH buffered peribulbar anaesthesia: a pilot study.
Topics: Analysis of Variance; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Lidocain | 2000 |
The effect of systemic lidocaine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers.
Topics: Adult; Anesthetics, Local; Capsaicin; Cross-Over Studies; Dizziness; Double-Blind Method; Hot Temper | 2000 |
Transanally injected triamcinolone acetonide in levator syndrome.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anus Diseases; Female; Humans | 2000 |
The incidence of transient neurological symptoms after spinal anaesthesia with lidocaine compared to prilocaine.
Topics: Adolescent; Adult; Aged; Anesthesia, Spinal; Anesthetics, Local; Double-Blind Method; Female; Humans | 2000 |
Topical lidocaine patch relieves a variety of neuropathic pain conditions: an open-label study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lidocai | 2000 |
Prilocaine versus lignocaine for minor lid procedures.
Topics: Anesthetics, Local; Double-Blind Method; Eyelids; Humans; Injections, Intradermal; Lidocaine; Pain; | 2000 |
Reduction in pain associated with open carpal tunnel decompression.
Topics: Anesthetics, Local; Carpal Tunnel Syndrome; Decompression, Surgical; Double-Blind Method; Female; Hu | 2000 |
Intrathecal methylprednisolone for intractable postherpetic neuralgia.
Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofe | 2000 |
Does local anesthesia at mid-trimester amniocentesis decrease pain experience? A randomized trial in 220 patients.
Topics: Adult; Amniocentesis; Anesthesia, Local; Anesthetics, Local; Chi-Square Distribution; Female; Humans | 2000 |
Pain during insertion of peripheral intravenous catheters with and without intradermal lidocaine.
Topics: Anesthetics, Local; Catheterization, Peripheral; Female; Humans; Injections, Intradermal; Lidocaine; | 1999 |
Is transient lumbar pain after spinal anaesthesia with lidocaine influenced by early mobilisation?
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Early Ambulation; Female; Hu | 2001 |
The effect of an intrauterine application of two percent lignocaine gel on pain perception during Vabra endometrial sampling: a randomised double-blind, placebo-controlled trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Double-Blind Me | 2001 |
[Relief of subacute herpetic pain and postherpetic neuralgia with repeated application of 10% lidocaine cream].
Topics: Aged; Anesthetics, Local; Female; Herpes Zoster; Humans; Lidocaine; Male; Middle Aged; Neuralgia; Oi | 2000 |
[Effect of pre-mixed lidocaine with propofol on propofol injection pain in elderly patients].
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Double-Blind Method; Drug Combinations; Female; | 2000 |
LET versus EMLA for pretreating lacerations: a randomized trial.
Topics: Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Female; Humans; | 2001 |
Comparison of EMLA cream versus placebo in children receiving distraction therapy for venepuncture.
Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Cognitive Behavioral Therapy; Double-Blind | 2001 |
Oral sucrose compares favourably with lidocaine-prilocaine cream for pain relief during venepuncture in neonates.
Topics: Administration, Oral; Anesthetics, Local; Crying; Double-Blind Method; Drug Combinations; Female; He | 2001 |
A comparative study of proxymetacaine-fluorescein and lignocaine-fluorescein use during applanation tonometry.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Coloring Agents; Double-Blind Method; Female; Fl | 2001 |
Reducing postnatal pain from perineal tears by using lignocaine gel: a double-blind randomized trial.
Topics: Administration, Topical; Adult; Analgesia, Obstetrical; Anesthetics, Local; Double-Blind Method; Fem | 2001 |
Effect of local anesthetics on patient recovery after transrectal biopsy.
Topics: Aged; Anesthesia, Local; Biopsy; Double-Blind Method; Humans; Lidocaine; Male; Pain; Pain Measuremen | 2001 |
Clinical evaluation and comparison of 2 topical anesthetics for pain caused by needle sticks and scaling and root planing.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Benzocaine; Bicuspid; Dental Arch; Dental | 2001 |
The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraqix) for periodontal scaling/root planing.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Combined; Anesthetics, Local; Dental Scalin | 2001 |
A randomised, double-blind, placebo-controlled, comparative study of topical skin analgesics and the anxiety and discomfort associated with venous cannulation.
Topics: Administration, Cutaneous; Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Combined; A | 2001 |
The use of pre-cannulation local anaesthetic and factors affecting pain perception in the emergency department setting.
Topics: Adolescent; Adult; Anesthetics, Local; Catheterization; Emergency Service, Hospital; Humans; Injecti | 2001 |
The WAND local anesthetic delivery system: a more pleasant experience for anal anesthesia.
Topics: Adult; Aged; Anal Canal; Anesthesia, Local; Anesthetics, Local; Anus Diseases; Equipment Design; Fem | 2001 |
Local anesthesia in the palate: a comparison of techniques and solutions.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bicuspid; Double-Blind Method; Epi | 2000 |
Epidural anesthesia with lidocaine reduces propofol injection pain.
Topics: Adult; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Fema | 2001 |
Eutectic mixture of local anesthetics reduces pain during intravenous catheter insertion in the pediatric patient.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 2001 |
Role of tramadol in reducing pain on propofol injection.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Me | 2001 |
Effect of ondansetron pretreatment on pain after rocuronium and propofol injection: a randomised, double-blind controlled comparison with lidocaine.
Topics: Adult; Androstanols; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Double-Blind Method; | 2001 |
Local anesthesia for ultrasound guided prostate biopsy: a prospective randomized trial comparing 2 methods.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Middle | 2001 |
Manipulation under anesthesia for frozen shoulder with and without steroid injection.
Topics: Activities of Daily Living; Anesthesia, Intravenous; Anesthetics, Local; Anti-Inflammatory Agents; B | 2001 |
EMLA or Ametop, and for how long?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Drug Administ | 2001 |
Lidocaine versus plain saline for pain relief in fractional curettage: a randomized controlled trial.
Topics: Adult; Analysis of Variance; Anesthetics, Local; Dilatation and Curettage; Double-Blind Method; Fema | 2001 |
Pain after transrectal ultrasonography-guided prostate biopsy: the advantages of periprostatic local anaesthesia.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Biopsy, Needle; Humans; Injections; Lidocaine; Male; Mi | 2001 |
Clinical effectiveness of lidocaine and benzocaine for topical anesthesia.
Topics: Adolescent; Adult; Analysis of Variance; Anesthesia, Local; Anesthetics, Local; Benzocaine; Double-B | 1999 |
Pain, photophobia, and retinal and optic nerve function after phacoemulsification with intracameral lidocaine.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Electroretinography; Evoked Potentials, Visual; | 2001 |
Flexible cystoscopy: is the volume and content of the urethral gel critical?
Topics: Aged; Anesthetics, Local; Cystoscopes; Cystoscopy; Gels; Humans; Lidocaine; Male; Middle Aged; Pain; | 2001 |
The effects of warming and buffering on pain of infiltration of lidocaine.
Topics: Adult; Analysis of Variance; Anesthetics, Local; Buffers; Double-Blind Method; Hot Temperature; Huma | 1995 |
[Efficacy of simultaneous bolus injection of lidocaine with propofol on pain caused by propofol injection].
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; Humans; Inje | 2001 |
Immediate versus delayed outpatient flexible cystoscopy: final report of a randomized study.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Cystoscopy; Follow-Up Studies; Gels; Humans; Lidocaine; | 2001 |
A randomized double-blind, placebo-controlled trial of the EMLA patch for the reduction of pain associated with intramuscular injection in four to six-year-old children.
Topics: Anesthetics, Combined; Child; Child, Preschool; Diphtheria-Tetanus-Pertussis Vaccine; Double-Blind M | 2001 |
Chloroprocaine is less painful than lidocaine for skin infiltration anesthesia.
Topics: Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Female; Humans; Hydro | 2002 |
Randomized prospective study of periprostatic local anesthesia during transrectal ultrasound-guided prostate biopsy.
Topics: Aged; Anesthesia, Local; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; Pain; Pain Measuremen | 2002 |
Tubal surface lidocaine mediates pre-emptive analgesia in awake laparoscopic sterilization: a prospective, randomized clinical trial.
Topics: Adult; Analgesia; Anesthetics, Local; Double-Blind Method; Fallopian Tubes; Female; Humans; Intraope | 2002 |
A study of lidocaine iontophoresis for pediatric venipuncture.
Topics: Adolescent; Anesthetics, Local; Child; Double-Blind Method; Female; Humans; Iontophoresis; Lidocaine | 2002 |
Rapid skin anaesthesia using high velocity lignocaine particles: a prospective placebo controlled trial.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Child; Child | 2002 |
Effect of the rate of delivery of lignocaine gel on patient discomfort perception prior to performing flexible cystoscopy.
Topics: Aged; Anesthesia, Local; Cystoscopy; Gels; Humans; Lidocaine; Male; Middle Aged; Pain; Pain Measurem | 2002 |
[Comparison between Greenbaum's parabulbar anesthesia and Ripart's subtenon anesthesia in the anterior segment surgery].
Topics: Anesthesia, Local; Anesthetics, Local; Anterior Eye Segment; Bupivacaine; Glaucoma; Humans; Lidocain | 2002 |
EMLA cream prior to digital nerve block for ingrown nail surgery does not reduce pain at injection of anesthetic solution.
Topics: Adolescent; Adult; Aged; Anesthetics, Combined; Child; Double-Blind Method; Female; Humans; Injectio | 2002 |
Photodynamic therapy for superficial bladder cancer under local anaesthetic.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Anesthesia, Local; Anesthetics, Local; Carcinoma, Tran | 2002 |
Lidocaine iontophoresis versus eutectic mixture of local anesthetics (EMLA) for IV placement in children.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Cross-Over Studies; Female; Humans; | 2002 |
The prevention of pain from injection of rocuronium by ondansetron, lidocaine, tramadol, and fentanyl.
Topics: Adult; Analgesics, Opioid; Androstanols; Anesthetics, Local; Double-Blind Method; Female; Fentanyl; | 2002 |
[Prevention of pain on injection with propofol in children: comparison of nitrous oxide with lidocaine].
Topics: Analgesics; Child; Humans; Hypnotics and Sedatives; Injections; Lidocaine; Nitrous Oxide; Pain; Pain | 2002 |
A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cross-Over Studies; | 2002 |
A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cross-Over Studies; | 2002 |
A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cross-Over Studies; | 2002 |
A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cross-Over Studies; | 2002 |
A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cross-Over Studies; | 2002 |
A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cross-Over Studies; | 2002 |
A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cross-Over Studies; | 2002 |
A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cross-Over Studies; | 2002 |
A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cross-Over Studies; | 2002 |
Iontophoretically applied lidocaine and the prevention of pain associated with the injection of intravenous propofol: a comparison with intravenous lidocaine.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; | 2002 |
The use of glyceryl trinitrate ointment with EMLA cream for i.v. cannulation in children undergoing routine surgery.
Topics: Administration, Topical; Adolescent; Anesthesia, Local; Catheterization, Peripheral; Child; Child, P | 2002 |
Local antiseptic therapy for non-gonococcal urethritis: phase II study with Instillagel.
Topics: Anti-Infective Agents, Local; Chlorhexidine; Colony Count, Microbial; Drug Combinations; Gonorrhea; | 2002 |
Comparison of local anesthesia techniques during transrectal ultrasound-guided biopsies.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Middle | 2002 |
Use of EMLA cream with vasectomy.
Topics: Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Humans; Injections; Lanolin; Lidocaine; | 2002 |
The use of intra-arterial lidocaine to control pain due to aortofemoral arteriography.
Topics: Angiography; Aorta; Clinical Trials as Topic; Contrast Media; Double-Blind Method; Femoral Artery; H | 1977 |
Pain associated with peripheral angiography: is lidocaine effective?
Topics: Aged; Angiography; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; Lidocain | 1978 |
Adjuvant intra-arterial lidocaine in aortofemoral arteriography: some further observations.
Topics: Aortography; Clinical Trials as Topic; Double-Blind Method; Femoral Artery; Humans; Lidocaine; Pain; | 1978 |
A double-blind crossover comparison of topical anesthetics.
Topics: Administration, Topical; Adult; Anesthetics, Local; Benzocaine; Clinical Trials as Topic; Double-Bli | 1979 |
[Analgesic effect of Neuro-Demoplas in a double-blind test].
Topics: Aminopyrine; Analgesics; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Humans; Lidoc | 1976 |
Complications after removal of mandibular third molars with special reference to local anaesthetics with different vasoactive properties.
Topics: Adolescent; Adult; Alveolar Process; Analgesics; Anesthesia, Dental; Clinical Trials as Topic; Deglu | 1975 |
EMLA partially relieves the pain of EMG needling.
Topics: Administration, Cutaneous; Adult; Aged; Anesthetics, Local; Drug Combinations; Elbow; Electrodes; El | 1992 |
Outpatient hysteroscopy: a comparison of 2 methods of local analgesia.
Topics: Ambulatory Surgical Procedures; Analgesia; Cervix Uteri; Female; Humans; Hysteroscopy; Lidocaine; Ne | 1992 |
Efficacy of lignocaine in alleviating potassium chloride infusion pain.
Topics: Adult; Aged; Analgesia; Double-Blind Method; Humans; Hypokalemia; Incidence; Infusions, Intravenous; | 1992 |
Analgesia for the reduction of Colles fracture. A comparison of hematoma block and intravenous sedation.
Topics: Adult; Analgesia; Anesthesia, Intravenous; Anesthesia, Local; Colles' Fracture; Diazepam; Double-Bli | 1992 |
Analgesia for the reduction of Colles fracture. A comparison of hematoma block and intravenous sedation.
Topics: Adult; Analgesia; Anesthesia, Intravenous; Anesthesia, Local; Colles' Fracture; Diazepam; Double-Bli | 1992 |
Analgesia for the reduction of Colles fracture. A comparison of hematoma block and intravenous sedation.
Topics: Adult; Analgesia; Anesthesia, Intravenous; Anesthesia, Local; Colles' Fracture; Diazepam; Double-Bli | 1992 |
Analgesia for the reduction of Colles fracture. A comparison of hematoma block and intravenous sedation.
Topics: Adult; Analgesia; Anesthesia, Intravenous; Anesthesia, Local; Colles' Fracture; Diazepam; Double-Bli | 1992 |
Local anaesthetic creams and intradermal skin tests.
Topics: Anesthetics, Local; Drug Combinations; Histamine; Humans; Injections, Intradermal; Lidocaine; Lidoca | 1992 |
Efficacy of lignocaine analgesia during treatment to the cervix.
Topics: Analgesia; Cold Temperature; Double-Blind Method; Female; Humans; Lidocaine; Pain; Pain Measurement; | 1992 |
Pain on injection of propofol: comparison of lignocaine with metoclopramide.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Ma | 1992 |
Warming lignocaine to reduce pain associated with injection.
Topics: Adult; Double-Blind Method; Female; Hot Temperature; Humans; Injections, Subcutaneous; Lidocaine; Ma | 1992 |
Local anaesthetic: does it really reduce the pain of insertion of all sizes of venous cannula?
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Catheterization, Peripheral; Female; Humans; Inje | 1992 |
A clinical evaluation of three topical anaesthetic agents.
Topics: Adult; Anesthetics, Local; Benzocaine; Double-Blind Method; Drug Combinations; Female; Humans; Injec | 1992 |
Pain perception and effectiveness of the eutectic mixture of local anesthetics in children undergoing venipuncture.
Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Evaluation Studies as Topic; Female; Humans | 1992 |
Injection pain, cardiovascular changes and recovery following induction of anaesthesia with propofol in combination with alfentanil or lignocaine in children.
Topics: Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Child; Child, Preschool; Double-Bli | 1992 |
Buffered lidocaine as a local anesthetic: an investigation of shelf life.
Topics: Adult; Double-Blind Method; Drug Stability; Drug Storage; Humans; Hydrogen-Ion Concentration; Inject | 1992 |
Buffered lidocaine as a local anesthetic: an investigation of shelf life.
Topics: Adult; Double-Blind Method; Drug Stability; Drug Storage; Humans; Hydrogen-Ion Concentration; Inject | 1992 |
Buffered lidocaine as a local anesthetic: an investigation of shelf life.
Topics: Adult; Double-Blind Method; Drug Stability; Drug Storage; Humans; Hydrogen-Ion Concentration; Inject | 1992 |
Buffered lidocaine as a local anesthetic: an investigation of shelf life.
Topics: Adult; Double-Blind Method; Drug Stability; Drug Storage; Humans; Hydrogen-Ion Concentration; Inject | 1992 |
A comparative study of transdermal 10% lidocaine gel with and without glycyrrhetinic acid monohemiphthalate disodium for pain reduction at venous cannulation.
Topics: Administration, Cutaneous; Catheterization, Peripheral; Double-Blind Method; Female; Glycyrrhetinic | 1992 |
Epidural fentanyl and caesarean section: when should fentanyl be given?
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Cesarean Section; Double-Blind Me | 1992 |
[Peridural anesthesia for surgery of the ankle and foot: effect of the sitting position].
Topics: Adult; Anesthesia, Epidural; Ankle; Blood Pressure; Foot; Humans; Lidocaine; Lumbar Vertebrae; Middl | 1992 |
Effect of lidocaine-prilocaine cream on pain from subcutaneous injection.
Topics: Administration, Topical; Adult; Anesthetics, Local; Double-Blind Method; Drug Combinations; Female; | 1992 |
Reduction of pain and local complications when buffered lidocaine solution is used as a local anesthetic in conjunction with hyperthermia treatments: results of a randomized trial.
Topics: Buffers; Catheterization; Female; Humans; Hydrogen-Ion Concentration; Hyperthermia, Induced; Lidocai | 1992 |
The minimum effective dose of lignocaine to prevent injection pain due to propofol in children.
Topics: Anesthesia, Intravenous; Anesthesia, Local; Child; Child, Preschool; Humans; Infant; Injections, Int | 1992 |
Inhibition of burn pain by intravenous lignocaine infusion.
Topics: Burns; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Intraveno | 1991 |
Diagnostic spinal anaesthesia in chronic spinal cord injury pain.
Topics: Adolescent; Adult; Anesthesia, Spinal; Chronic Disease; Dose-Response Relationship, Drug; Female; Hu | 1991 |
Lidocaine for the prevention of pain due to injection of propofol.
Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenou | 1992 |
Tourniquet at 50 mm Hg followed by intravenous lidocaine diminishes hand pain associated with propofol injection.
Topics: Adult; Drug Evaluation; Female; Hand; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; | 1992 |
Taking the 'sting' out of local anaesthetics.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Double-Blind Method; Drug Compounding | 1991 |
Thickly and thinly applied lignocaine-prilocaine cream prior to venepuncture in children.
Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Bloodletting; Child; Child Behavior; Chil | 1991 |
Does combined epidural lignocaine and fentanyl provide better anaesthesia for ESWL than lignocaine alone?
Topics: Anesthesia, Epidural; Double-Blind Method; Drug Combinations; Female; Fentanyl; Humans; Kidney Calcu | 1991 |
[Gonalgia: treatment with therapeutic local anesthesia. Results of a controlled comparative study versus diclofenac].
Topics: Adult; Anesthesia, Local; Diclofenac; Female; Humans; Knee Joint; Lidocaine; Male; Middle Aged; Pain | 1991 |
Effect of prior administration of cold saline on pain during propofol injection. A comparison with cold propofol and propofol with lignocaine.
Topics: Adult; Aged; Anesthesia, Intravenous; Cold Temperature; Female; Humans; Lidocaine; Male; Middle Aged | 1991 |
Is intravenous lidocaine clinically effective in acute migraine?
Topics: Acute Disease; Adult; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; | 1991 |
Epilation of upper lip hirsutism with a eutectic mixture of lidocaine and prilocaine used as a topical anesthetic.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Diathermy; Double-Blind Method; Drug Combination | 1991 |
Iliac crest pain syndrome in low back pain. A double blind, randomized study of local injection therapy.
Topics: Adult; Back Pain; Double-Blind Method; Female; Humans; Ilium; Injections; Lidocaine; Lumbosacral Reg | 1991 |
Pain on intradermal injection with lignocaine. The effect of concentration.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Humans; Injections, Intradermal; Lidocaine; P | 1991 |
Topical glyceryl trinitrate and eutectic mixture of local anaesthetics in children. A randomised controlled trial on choice of site and ease of venous cannulation.
Topics: Administration, Topical; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; D | 1991 |
Pain control in the surgical debridement of leg ulcers by the use of a topical lidocaine--prilocaine cream, EMLA.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Debridement; Double-Bli | 1990 |
A quantitative comparison of the effect of local analgesics on argon laser induced cutaneous pain and on histamine induced wheal, flare and itch.
Topics: Administration, Topical; Adult; Anesthetics, Local; Drug Combinations; Emollients; Female; Histamine | 1990 |
Prevention of pain during injection of propofol.
Topics: Drug Therapy, Combination; Humans; Injections, Intravenous; Lidocaine; Pain; Premedication; Propofol | 1990 |
Local injection treatment of tennis elbow--hydrocortisone, triamcinolone and lignocaine compared.
Topics: Adult; Drug Combinations; Elbow; Female; Humans; Hydrocortisone; Injections; Lidocaine; Male; Middle | 1991 |
Local injection treatment of tennis elbow--hydrocortisone, triamcinolone and lignocaine compared.
Topics: Adult; Drug Combinations; Elbow; Female; Humans; Hydrocortisone; Injections; Lidocaine; Male; Middle | 1991 |
Local injection treatment of tennis elbow--hydrocortisone, triamcinolone and lignocaine compared.
Topics: Adult; Drug Combinations; Elbow; Female; Humans; Hydrocortisone; Injections; Lidocaine; Male; Middle | 1991 |
Local injection treatment of tennis elbow--hydrocortisone, triamcinolone and lignocaine compared.
Topics: Adult; Drug Combinations; Elbow; Female; Humans; Hydrocortisone; Injections; Lidocaine; Male; Middle | 1991 |
Local injection treatment of tennis elbow--hydrocortisone, triamcinolone and lignocaine compared.
Topics: Adult; Drug Combinations; Elbow; Female; Humans; Hydrocortisone; Injections; Lidocaine; Male; Middle | 1991 |
Local injection treatment of tennis elbow--hydrocortisone, triamcinolone and lignocaine compared.
Topics: Adult; Drug Combinations; Elbow; Female; Humans; Hydrocortisone; Injections; Lidocaine; Male; Middle | 1991 |
Local injection treatment of tennis elbow--hydrocortisone, triamcinolone and lignocaine compared.
Topics: Adult; Drug Combinations; Elbow; Female; Humans; Hydrocortisone; Injections; Lidocaine; Male; Middle | 1991 |
Local injection treatment of tennis elbow--hydrocortisone, triamcinolone and lignocaine compared.
Topics: Adult; Drug Combinations; Elbow; Female; Humans; Hydrocortisone; Injections; Lidocaine; Male; Middle | 1991 |
Local injection treatment of tennis elbow--hydrocortisone, triamcinolone and lignocaine compared.
Topics: Adult; Drug Combinations; Elbow; Female; Humans; Hydrocortisone; Injections; Lidocaine; Male; Middle | 1991 |
Modification of pain on injection of propofol--a comparison between lignocaine and procaine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Anesthesia, Local; Humans; Lido | 1991 |
A quantitative double-blind evaluation of the antinociceptive effects of perineurally administered morphine compared with lidocaine.
Topics: Adult; Double-Blind Method; Evoked Potentials, Somatosensory; Female; Humans; Lidocaine; Male; Morph | 1991 |
A double-masked evaluation of lignocaine-prilocaine cream (EMLA) used to alleviate the pain of retrobulbar injection.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cataract Extraction; Do | 1991 |
Optimal dose of lignocaine for preventing pain on injection of propofol.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Double-Blind Method; Female; Hu | 1991 |
Assessing pain and analgesia with a lidocaine-prilocaine emulsion in infants and toddlers during venipuncture.
Topics: Anesthetics, Local; Bloodletting; Child Behavior; Child, Preschool; Double-Blind Method; Drug Combin | 1991 |
A controlled study of low and high volume anesthetic jelly as a lubricant and pain reliever during cystoscopy.
Topics: Aging; Anesthesia, Local; Cystoscopes; Cystoscopy; Female; Gels; Humans; Lidocaine; Lubrication; Mal | 1991 |
Reduction in injection pain using buffered lidocaine as a local anesthetic before cardiac catheterization.
Topics: Anesthesia, Local; Cardiac Catheterization; Double-Blind Method; Female; Humans; Hydrogen-Ion Concen | 1991 |
[The effect of epidural anesthesia on tourniquet pain: a comparison of 2% lidocaine and 0.5% bupivacaine].
Topics: Adult; Aged; Anesthesia, Epidural; Bupivacaine; Female; Humans; Lidocaine; Male; Middle Aged; Pain; | 1990 |
Local application of EMLA and glyceryl trinitrate ointment before venepuncture.
Topics: Administration, Cutaneous; Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Loc | 1990 |
pH-adjustment and discomfort caused by the intradermal injection of lignocaine.
Topics: Adult; Anesthesia, Local; Bicarbonates; Epinephrine; Female; Humans; Hydrogen-Ion Concentration; Inj | 1990 |
[The modification of injection pain and the incidence of thrombophlebitis following etomidate].
Topics: Adult; Aged; Anesthesia, Intravenous; Clinical Trials as Topic; Constriction; Double-Blind Method; E | 1990 |
The effect, on injection pain, of adding lignocaine to propofol.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Double-Blind Method; Female; Humans; Injections, Intrave | 1990 |
Pain on injection of propofol. Methods of alleviation.
Topics: Double-Blind Method; Humans; Injections, Intravenous; Lidocaine; Mental Recall; Pain; Propofol; Rand | 1990 |
Pain on injection of propofol. Methods of alleviation.
Topics: Double-Blind Method; Humans; Injections, Intravenous; Lidocaine; Mental Recall; Pain; Propofol; Rand | 1990 |
Pain on injection of propofol. Methods of alleviation.
Topics: Double-Blind Method; Humans; Injections, Intravenous; Lidocaine; Mental Recall; Pain; Propofol; Rand | 1990 |
Pain on injection of propofol. Methods of alleviation.
Topics: Double-Blind Method; Humans; Injections, Intravenous; Lidocaine; Mental Recall; Pain; Propofol; Rand | 1990 |
Ethyl chloride and venepuncture pain: a comparison with intradermal lidocaine.
Topics: Administration, Cutaneous; Aerosols; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesi | 1990 |
Ethyl chloride and venepuncture pain: a comparison with intradermal lidocaine.
Topics: Administration, Cutaneous; Aerosols; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesi | 1990 |
Ethyl chloride and venepuncture pain: a comparison with intradermal lidocaine.
Topics: Administration, Cutaneous; Aerosols; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesi | 1990 |
Ethyl chloride and venepuncture pain: a comparison with intradermal lidocaine.
Topics: Administration, Cutaneous; Aerosols; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesi | 1990 |
EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream.
Topics: Anesthetics, Local; Catheterization, Peripheral; Double-Blind Method; Drug Combinations; Humans; Lid | 1990 |
Double-blind comparison of topical lignocaine-prilocaine cream (EMLA) and lignocaine infiltration for arterial cannulation in adults.
Topics: Administration, Topical; Adult; Anesthetics, Local; Catheterization; Double-Blind Method; Drug Combi | 1990 |
Relief of injection pain in adults. EMLA cream for 5 minutes before venepuncture.
Topics: Administration, Topical; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anesthetics, Local | 1990 |
Buffered versus plain lidocaine as a local anesthetic for simple laceration repair.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Buffers; Double-Blind Method; Emergencies; Femal | 1990 |
Buffered versus plain lidocaine as a local anesthetic for simple laceration repair.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Buffers; Double-Blind Method; Emergencies; Femal | 1990 |
Buffered versus plain lidocaine as a local anesthetic for simple laceration repair.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Buffers; Double-Blind Method; Emergencies; Femal | 1990 |
Buffered versus plain lidocaine as a local anesthetic for simple laceration repair.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Buffers; Double-Blind Method; Emergencies; Femal | 1990 |
Our experience with EMLA Cream (for painless venous cannulation in children).
Topics: Anesthetics, Local; Anxiety; Catheterization, Peripheral; Child; Child, Preschool; Drug Combinations | 1990 |
Bicarbonate-buffered lidocaine-epinephrine-hyaluronidase for eyelid anesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bicarbonates; Buffers; Cataract Extraction; Doub | 1990 |
Long- or short-acting anesthetic with corticosteroid in local injections of overuse injuries? A prospective, randomized, double-blind study.
Topics: Adolescent; Adult; Athletic Injuries; Bupivacaine; Cumulative Trauma Disorders; Double-Blind Method; | 1990 |
Towards less painful local anesthesia.
Topics: Adult; Anesthesia, Local; Double-Blind Method; Humans; Hydrogen-Ion Concentration; Lidocaine; Middle | 1990 |
The effect of intravenous lidocaine on nociceptive processing in diabetic neuropathy.
Topics: Adult; Diabetic Neuropathies; Double-Blind Method; H-Reflex; Humans; Injections, Intravenous; Lidoca | 1990 |
Does EMLA reduce the discomfort associated with local-anaesthetic infiltration?
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Double-Bl | 1990 |
Reducing the pain of intradermal lignocaine injection by pH buffering.
Topics: Adolescent; Adult; Buffers; Humans; Hydrogen-Ion Concentration; Injections, Intradermal; Lidocaine; | 1990 |
Prophylactic lidocaine in the prehospital patient with chest pain of suspected cardiac origin.
Topics: Adult; Age Factors; Aged; Angina, Unstable; Arrhythmias, Cardiac; Blood Pressure; Cardiac Complexes, | 1986 |
A comparison of regional intravenous guanethidine and reserpine in reflex sympathetic dystrophy. A controlled, randomized, double-blind crossover study.
Topics: Adult; Body Temperature; Double-Blind Method; Female; Guanethidine; Humans; Injections, Intravenous; | 1989 |
Trial of intravenous lidocaine on painful neuropathy in cancer patients.
Topics: Adult; Aged; Double-Blind Method; Electrocardiography; Female; Humans; Injections, Intravenous; Lido | 1989 |
Repeated application of EMLA cream 5% for the alleviation of cannulation pain in haemodialysis.
Topics: Aged; Anesthetics, Local; Catheterization, Central Venous; Dermatitis, Contact; Double-Blind Method; | 1989 |
Propofol as an induction agent in children: pain on injection and pharmacokinetics.
Topics: Anesthetics; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Combinatio | 1989 |
Effect of a eutectic mixture of local anaesthetic agents (EMLA) on tourniquet pain in volunteers.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Drug Combinations; Humans; Lidoca | 1989 |
The efficacy of paracervical injections of lignocaine before laser ablation of the cervical transformation zone. A randomized placebo-controlled double-blind clinical trial.
Topics: Cervix Uteri; Double-Blind Method; Female; Humans; Injections; Laser Therapy; Lidocaine; Pain; Pain | 1989 |
Pain responses to perineuromal injection of normal saline, gallamine, and lidocaine in humans.
Topics: Adult; Aged; Gallamine Triethiodide; Humans; Lidocaine; Middle Aged; Neuroma; Pain; Pain Measurement | 1989 |
Topical skin anesthesia for venous, subcutaneous drug reservoir and lumbar punctures in children.
Topics: Adolescent; Anesthetics, Local; Bloodletting; Child; Child, Preschool; Drug Combinations; Female; Hu | 1989 |
The effect of topically applied anaesthetics (EMLA cream) on thresholds to thermode and argon laser stimulation.
Topics: Administration, Cutaneous; Anesthetics, Local; Argon; Cold Temperature; Drug Combinations; Hot Tempe | 1989 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
The use of lidocaine to reduce the pain of myochrysine injections for children with juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Child; Drug Combinations; Gold Sodium Thiomalate; Humans; Injections, Intramuscul | 1986 |
Topical anaesthesia for fistula cannulation in haemodialysis patients.
Topics: Adult; Aged; Anesthetics, Local; Catheters, Indwelling; Clinical Trials as Topic; Double-Blind Metho | 1988 |
Propofol: clinical strategies for preventing the pain of injection.
Topics: Adolescent; Adult; Aged; Anesthetics; Humans; Injections, Intravenous; Lidocaine; Middle Aged; Pain; | 1988 |
The reduction of pain on injection of propofol: the effect of addition of lignocaine.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics; Double-Blind Method; Female; Humans; Inject | 1988 |
Pain-free injection in infants. Use of a lignocaine-prilocaine cream to prevent pain at intravenous induction of general anaesthesia in 1-5-year-old children.
Topics: Anesthesia, General; Anesthetics, Local; Child, Preschool; Clinical Trials as Topic; Double-Blind Me | 1988 |
A clinical comparison of lidocaine and bupivacaine.
Topics: Adult; Bupivacaine; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Emergencies; Fem | 1987 |
Randomized, double-blind, placebo-controlled study of the treatment of the painful shoulder.
Topics: Bursa, Synovial; Bursitis; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; | 1987 |
Delayed hypersensitivity responses in children after local cutaneous anesthesia.
Topics: Adolescent; Anesthesia, Local; Antigens; Child; Clinical Trials as Topic; Humans; Hypersensitivity, | 1987 |
EMLA cream reduces the pain of venepuncture in children.
Topics: Anesthesia, Intravenous; Anesthetics, Local; Child; Child, Preschool; Clinical Trials as Topic; Doub | 1987 |
Local anesthesia for neonatal circumcision. Effects on distress and cortisol response.
Topics: Circumcision, Male; Crying; Double-Blind Method; Humans; Hydrocortisone; Infant, Newborn; Lidocaine; | 1988 |
Distress caused by urethral catheters.
Topics: Aged; Catheters, Indwelling; Female; Humans; Lidocaine; Pain; Placebos; Urethra; Urinary Catheteriza | 1988 |
Reduction of pain at venous cannulation in children with a eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication.
Topics: Administration, Cutaneous; Anesthetics, Local; Anxiety; Catecholamines; Catheterization, Peripheral; | 1987 |
Electromyography and bite force studies of muscular function and dysfunction in masticatory muscles.
Topics: Bite Force; Dental Occlusion; Double-Blind Method; Electromyography; Facial Pain; Female; Humans; Is | 1986 |
Double-blind evaluation of a lignocaine-prilocaine cream (EMLA) in children. Effect on the pain associated with venous cannulation.
Topics: Anesthesia, Local; Attitude to Health; Catheterization; Child; Child, Preschool; Clinical Trials as | 1986 |
Topical anaesthesia for venepuncture.
Topics: Administration, Topical; Adolescent; Anesthesia, Local; Child; Child, Preschool; Clinical Trials as | 1986 |
Diclofenac versus lidocaine as injection therapy in myofascial pain.
Topics: Diclofenac; Female; Humans; Injections, Intramuscular; Lidocaine; Male; Middle Aged; Myofascial Pain | 1986 |
Intravenous lidocaine infusion--a new treatment of chronic painful diabetic neuropathy?
Topics: Adult; Chronic Disease; Diabetic Neuropathies; Double-Blind Method; Female; Humans; Infusions, Intra | 1987 |
Dercum's disease (adiposis dolorosa). Treatment of the severe pain with intravenous lidocaine.
Topics: Adiposis Dolorosa; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Injections, | 1987 |
Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Child, Preschool; Drug Combinations; Humans; In | 1985 |
[Pain relief in vein puncture. Application time and effectiveness of lidocaine-prilocaine-cream].
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; | 1985 |
A lignocaine-prilocaine cream reduces venipuncture pain.
Topics: Anesthetics, Local; Child; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Humans; | 1985 |
Lidocaine reduces intravenous diazepam pain.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; In | 1985 |
Clinical study of a lignocaine-prilocaine cream to relieve the pain of venepuncture.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Double-Blind Method; Drug Combinatio | 1985 |
Psychomotor skills related to driving after intramuscular lidocaine.
Topics: Adolescent; Adult; Attention; Automobile Driving; Clinical Trials as Topic; Drug Combinations; Epine | 1974 |
A study of the local reaction to intramuscular disodium carbenicillin (Geopen).
Topics: Adult; Carbenicillin; Clinical Trials as Topic; Humans; Injections, Intramuscular; Lidocaine; Male; | 1972 |
A double-blind trial of bupivacaine and lignocaine. Latency and duration in extradural blockade.
Topics: Adult; Aged; Analgesia; Anesthesia, Spinal; Anesthetics, Local; Anilides; Clinical Trials as Topic; | 1968 |
The effectiveness of a teething solution in infants. A clinical study.
Topics: Age Factors; Alcohols; Anesthetics, Local; Child, Preschool; Clinical Trials as Topic; Female; Human | 1969 |
1003 other studies available for lidocaine and Ache
| Article | Year |
|---|---|
Search for anticonvulsant and analgesic active derivatives of dihydrofuran-2(3H)-one.
Topics: 4-Butyrolactone; Analgesics; Anesthetics, Local; Animals; Anticonvulsants; Dose-Response Relationshi | 2012 |
Lidocaine for Reduction of Pain Induced by Propofol in a Tertiary Care Hospital: A Descriptive Cross-sectional Study.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Cross-Sectional Studies; Doub | 2021 |
Efficacy of additional periprostatic apex nerve block on pain in each of 12 transrectal prostate core biopsies: a retrospective study.
Topics: Aged; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Pain; P | 2021 |
Application of Topical Lidocaine for Pain Relief in the Setting of Targeted Therapy-Induced Onycholysis: A Case Report.
Topics: Humans; Lidocaine; Onycholysis; Pain | 2022 |
Development and optimization of tibezonium iodide and lignocaine hydrochloride containing novel mucoadhesive buccal tablets: a pharmacokinetic investigation among healthy humans.
Topics: Adhesiveness; Administration, Buccal; Benzodiazepines; Humans; Hypromellose Derivatives; Iodides; Li | 2021 |
A Retrospective Study of Topical Lidocaine 5% Plasters in Chronic Off-Label Pain Conditions.
Topics: Administration, Topical; Anesthetics, Local; Humans; Lidocaine; Off-Label Use; Pain; Retrospective S | 2021 |
Evaluation of Pain and Distress and Therapeutic Interventions for Rectal Prolapse in Mice to Reduce Early Study Removal.
Topics: Animals; Lidocaine; Mice; Pain; Rectal Prolapse; Rectum | 2021 |
Real-life experience of a lidocaine/tetracaine self-occluding topical anesthetic for dermatological procedures.
Topics: Administration, Topical; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Pain; Pain Meas | 2022 |
Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro.
Topics: Anesthetics, Local; Bupivacaine; Cell Survival; Cells, Cultured; Chondrocytes; Drug Therapy, Combina | 2021 |
The use of lidocaine spray (Xylocaine) as a topical anaesthetic for minor ear procedures.
Topics: Anesthesia, Local; Anesthetics, Local; Humans; Lidocaine; Middle Ear Ventilation; Pain | 2022 |
Wide Awake Local Anesthesia No Tourniquet Technique in Hand Surgery: The Patient Experience.
Topics: Anesthesia, Local; Brain Neoplasms; Bupivacaine; Epinephrine; Hand; Humans; Lidocaine; Pain; Patient | 2023 |
TRANSCARUNCULAR DOUBLE INJECTION TECHNIQUE FOR PERIBULBAR ANESTHESIA IN VITREORETINAL SURGERY.
Topics: Anesthesia, Local; Anesthetics, Local; Bupivacaine; Humans; Lidocaine; Pain; Vitreoretinal Surgery | 2023 |
The Radial Synergy Test: An Aid to Diagnose de Quervain's Tenosynovitis.
Topics: De Quervain Disease; Humans; Lidocaine; Pain; Prospective Studies; Retrospective Studies; Tenosynovi | 2023 |
Caffeine Consumption Influences Lidocaine Action via Pain-Related Voltage-Gated Sodium Channels: An In Vivo Animal Study.
Topics: Anesthetics, Local; Animals; Caffeine; Drug Interactions; Humans; Lidocaine; Pain; Rats; Rats, Wista | 2022 |
Exclusive manual perineal rehabilitation with lidocaine 2% gel in the treatment of provoked vestibulodynia: results from a single-arm interventional study.
Topics: Adult; Female; Humans; Lidocaine; Pain; Quality of Life; Surveys and Questionnaires; Treatment Outco | 2023 |
Evaluation of the 4-point regional nerve block using 2% lidocaine in sheep.
Topics: Animals; Female; Lameness, Animal; Lidocaine; Nerve Block; Pain; Pain Measurement; Sheep; Sheep Dise | 2022 |
Lidocaine Infusion for the Treatment of Headache Associated With Subarachnoid Hemorrhage: A Case Report.
Topics: Analgesics, Opioid; Headache; Humans; Lidocaine; Pain; Subarachnoid Hemorrhage | 2022 |
I.V. lidocaine and opioid: Adjunctive therapy for pain management.
Topics: Analgesics, Opioid; Anesthetics, Local; Humans; Lidocaine; Pain; Pain Management | 2022 |
A high-dosage microneedle for programmable lidocaine delivery and enhanced local long-lasting analgesia.
Topics: Administration, Cutaneous; Analgesia; Animals; Lidocaine; Needles; Pain; Rats | 2022 |
Designer self-assembling peptide nanofibers induce biomineralization of lidocaine for slow-release and prolonged analgesia.
Topics: Analgesia; Analgesics; Biomineralization; Humans; Lidocaine; Nanofibers; Pain; Peptides; Water | 2022 |
A sequential allocation study to determine the ED
Topics: Anesthesia, Conduction; Anesthetics, Local; Clonidine; Dexmedetomidine; Double-Blind Method; Humans; | 2022 |
Mechanical nociceptive assessment of the equine hoof after navicular bursa anesthetic infiltration validated by bursography.
Topics: Anesthetics, Local; Animals; Bursa, Synovial; Forelimb; Hoof and Claw; Horse Diseases; Horses; Lidoc | 2022 |
Antinociceptive effect of lidocaine, tramadol, and their combination for lumbosacral epidural analgesia in rabbits undergoing experimental knee surgery.
Topics: Analgesia, Epidural; Analgesics; Animals; Lidocaine; Male; Pain; Rabbits; Tramadol | 2022 |
Translator use not associated with longer time to pain medication in initial evaluation of low-severity geriatric trauma.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Female; Humans; Lidocaine; Male; Pain; Retrospective Studie | 2022 |
The changes in levels of blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction.
Topics: Anesthetics, Local; Diabetes Mellitus, Type 2; Epinephrine; Glucose; Humans; Hydrocortisone; Lidocai | 2022 |
Comparison of the onset, depth, and duration of cutaneous anesthesia between topical 10% lidocaine and EMLA creams: a randomized, intraindividual, comparative trial.
Topics: Anesthesia; Anesthetics, Local; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Ointments | 2022 |
Ultrasound-guided 5-in-1 trigger point injection for treating tension-type headache: A case report.
Topics: Adult; Female; Humans; Lidocaine; Pain; Tension-Type Headache; Trigger Points; Ultrasonography, Inte | 2022 |
Phlegmasia cerulea dolens causing compartment syndrome.
Topics: Compartment Syndromes; Edema; Female; Humans; Hydromorphone; Lidocaine; Middle Aged; Pain; Thromboph | 2022 |
Lidocaine spray 10% prior to intravenous catheterisation in dogs.
Topics: Anesthetics, Local; Animals; Catheterization; Dogs; Double-Blind Method; Humans; Lidocaine; Pain; Pr | 2022 |
Ultrasound-Guided Capsular Thyroid Injection Therapy With Dexamethasone and Lidocaine Mixture for Subacute Thyroiditis: A Single-Center Study.
Topics: COVID-19; COVID-19 Drug Treatment; Dexamethasone; Humans; Hypothyroidism; Lidocaine; Pain; Thyroidit | 2023 |
Analgesic Effect and Safety of Lidocaine Liposome vs Oral Sucrose Water in Blood Collection and Intramuscular Injection in Neonates.
Topics: Analgesics; Humans; Infant, Newborn; Injections, Intramuscular; Lidocaine; Liposomes; Pain; Sucrose | 2023 |
Printed graphene-based electrochemical sensor with integrated paper microfluidics for rapid lidocaine detection in blood.
Topics: Biosensing Techniques; Electrochemical Techniques; Electrodes; Graphite; Humans; Lidocaine; Microflu | 2022 |
Successful treatment of notalgia paresthetica with lidocaine 5% medicated plaster: a case report.
Topics: Aged; Female; Humans; Lidocaine; Pain; Paresthesia; Peripheral Nervous System Diseases; Pruritus | 2022 |
Swelling of Multilayered Calcium Alginate Microspheres for Drug-Loaded Dressing Induced Rapid Lidocaine Release for Better Pain Control.
Topics: Alginates; Bandages; Chitosan; Gelatin; Humans; Lidocaine; Microspheres; Pain | 2022 |
A comparison of sub-tenon block with peribulbar block in small-incision cataract surgery.
Topics: Anesthesia, Local; Anesthetics, Local; Cataract; Cataract Extraction; Humans; India; Lidocaine; Opht | 2022 |
N(Omega)-nitro-l-arginine methyl ester potentiates lidocaine analgesic and anaesthetic effect in rats.
Topics: Analgesics; Anesthetics; Animals; Lidocaine; NG-Nitroarginine Methyl Ester; Pain; Rats; Rats, Spragu | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; L | 2023 |
Real-world effect of the treatment for painful subacute thyroiditis: The combined injection of lidocaine and triamcinolone using an insulin pen.
Topics: Anesthetics, Local; Humans; Insulins; Lidocaine; Pain; Thyroiditis, Subacute; Treatment Outcome; Tri | 2023 |
Real-world effect of the treatment for painful subacute thyroiditis: The combined injection of lidocaine and triamcinolone using an insulin pen.
Topics: Anesthetics, Local; Humans; Insulins; Lidocaine; Pain; Thyroiditis, Subacute; Treatment Outcome; Tri | 2023 |
Real-world effect of the treatment for painful subacute thyroiditis: The combined injection of lidocaine and triamcinolone using an insulin pen.
Topics: Anesthetics, Local; Humans; Insulins; Lidocaine; Pain; Thyroiditis, Subacute; Treatment Outcome; Tri | 2023 |
Real-world effect of the treatment for painful subacute thyroiditis: The combined injection of lidocaine and triamcinolone using an insulin pen.
Topics: Anesthetics, Local; Humans; Insulins; Lidocaine; Pain; Thyroiditis, Subacute; Treatment Outcome; Tri | 2023 |
Efficacy of lidocaine on preventing incidence and severity of pain associated with propofol using in pediatric patients: A PRISMA-compliant meta-analysis of randomized controlled trials: Erratum.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Child; Double-Blind Method; Humans; Incidence; Injecti | 2022 |
Differential diagnosis of paracervical vascular anomalies in pregnancy.
Topics: Anesthesia, Obstetrical; Aneurysm, False; Angiography; Diagnosis, Differential; Female; Humans; Lido | 2023 |
Pain of local anesthetic injection of lidocaine during subsequent stages of Mohs micrographic surgery: A multicenter prospective cohort study.
Topics: Adult; Anesthetics, Local; Humans; Lidocaine; Longitudinal Studies; Mohs Surgery; Pain; Prospective | 2023 |
Topical Lidocaine and Morphine Gel Use for Malignant Wound Pain.
Topics: Administration, Topical; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Morphine; Morph | 2023 |
Lidocaine Tape Application for 3 Hours Prevents Vasovagal Syncope During Venipuncture: A Case Series.
Topics: Anesthetics, Local; Humans; Lidocaine; Pain; Phlebotomy; Syncope, Vasovagal | 2023 |
A Comparative Analysis of Local Anesthetics: Injection Associated Pain and Duration of Anesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Benzyl Alcohol; Double-Blind Method; Epinephrine; Humans; Lid | 2023 |
Lidocaine aerosol sprayed on oral and/or nasal mucosa for the rescue of acute trigeminal neuralgia exacerbations: A retrospective study.
Topics: Aerosols; Humans; Lidocaine; Nasal Mucosa; Pain; Retrospective Studies; Treatment Outcome; Trigemina | 2023 |
Association Between Single-nucleotide Polymorphisms in Candidate Genes and Success of Pulpal Anesthesia after Inferior Alveolar Nerve Block.
Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Double-Blind Method; Female; Humans; Lidocaine; | 2023 |
Preoperative protocol for right flank laparotomy affects postoperative serum cortisol concentrations in dairy cows.
Topics: Animals; Cattle; Female; Hydrocortisone; Laparotomy; Lidocaine; Pain; Xylazine | 2023 |
Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Hum | 2023 |
Open Label, Pilot Evaluation of the Safety and Efficacy of Intravesical Sustained Release System of Lidocaine and Oxybutynin (TRG-100) for Patients With Interstitial Cystitis/Bladder Pain Syndrome, Overactive Bladder and Patients With Retained Ureteral St
Topics: Administration, Intravesical; Cystitis, Interstitial; Delayed-Action Preparations; Humans; Lidocaine | 2023 |
The effects of greater occipital nerve blockage with lidocaine on sleep characteristics in chronic migraine patients.
Topics: Adult; Female; Humans; Lidocaine; Middle Aged; Migraine Disorders; Pain; Sleep; Sleep Initiation and | 2023 |
Effectiveness of Eutectic Mixture of Local Anesthetics in Preventing Postoperative Sore Throat.
Topics: Anesthetics, Local; Humans; Intubation, Intratracheal; Lidocaine; Lidocaine, Prilocaine Drug Combina | 2023 |
[Application value and safety of prostate peripheral nerve block combined with dezocine in transrectal prostate biopsy].
Topics: Anesthetics, Local; Biopsy; Humans; Lidocaine; Male; Nerve Block; Pain; Prostate | 2022 |
Behavioral changes in the first 3 weeks after disbudding in dairy calves.
Topics: Animals; Cattle; Female; Horns; Iron; Lidocaine; Meloxicam; Pain | 2023 |
Perioperative Lidocaine Infusions and Pain Measurements: Effect Size Matters.
Topics: Humans; Lidocaine; Pain | 2023 |
Mpox Pain Management with Topical Agents: A Case Series.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Humans; Lidocaine; Mpox (monkeypox); Pain; P | 2023 |
Temperature-sensitive multifunctional intelligent responsive hydrogel based on carboxymethyl agarose and N-isopropylacrylamide: Controlled drug release and accelerated wound healing.
Topics: Acrylamides; Anti-Bacterial Agents; Drug Liberation; Humans; Hydrogels; Lidocaine; Pain; Polymers; S | 2023 |
Can Achilles tendinosis be treated effectively with lidocaine and glucose infiltrations, and if so, is the effect lasting? A longitudinal, observational on 27 consecutive patients.
Topics: Achilles Tendon; Activities of Daily Living; Glucose; Humans; Lidocaine; Longitudinal Studies; Pain; | 2023 |
[Management of puncture pain in hospitalized children].
Topics: Child; Child, Hospitalized; Child, Preschool; Humans; Lidocaine; Pain; Punctures; Retrospective Stud | 2022 |
Experimental Study of Tumescence Injection to Provide Anesthesia Without Local Anesthetics.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Disease Models, Animal; Dose-Response Relationship, | 2020 |
Intravenous Lidocaine for Relief of Chronic Neuropathic Pain.
Topics: Anesthetics, Local; Female; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Nurse Anes | 2019 |
Repeated Intravenous Lidocaine Infusions for Patients with Fibromyalgia: Higher Doses of Lidocaine Have a Stronger and Longer-Lasting Effect on Pain Reduction.
Topics: Anesthetics, Local; Fibromyalgia; Humans; Infusions, Intravenous; Lidocaine; Pain; Pain Measurement; | 2020 |
Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation.
Topics: Animals; Bupivacaine; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Signaling | 2019 |
Percutaneous Endoscopic Interlaminar Lumbar Discectomy with Local Anesthesia for L5-S1 Disc Herniation: A Feasibility Study.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthesia, Local; Diskectomy, Percutaneous; En | 2019 |
Intra-Arterial Lidocaine Administration for Anesthesia after Uterine Artery Embolization with Trisacryl Gelatin Microspheres for Leiomyoma.
Topics: Acrylic Resins; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Drug A | 2020 |
Intra-Arterial Lidocaine Is Not Found to Be Effective for Reducing Pain after Uterine Fibroid Embolization in a Retrospective Study: Now What?
Topics: Acrylic Resins; Anesthesia; Female; Gelatin; Humans; Leiomyoma; Lidocaine; Pain; Retrospective Studi | 2020 |
Analgesic efficacy of an intravenous constant rate infusion of a morphine-lidocaine-ketamine combination in Holstein calves undergoing umbilical herniorrhaphy.
Topics: Analgesics; Animals; Cattle; Female; Hernia, Umbilical; Herniorrhaphy; Hydrocortisone; Infusions, In | 2020 |
Sustained Release of Levobupivacaine, Lidocaine, and Acemetacin from Electrosprayed Microparticles: In Vitro and In Vivo Studies.
Topics: 3T3 Cells; Analgesics; Animals; Delayed-Action Preparations; Disease Models, Animal; Drug Compoundin | 2020 |
Conditioned place preference reveals ongoing pain in calves 3 weeks after disbudding.
Topics: Air Conditioning; Animal Husbandry; Animals; Cattle; Horns; Lidocaine; Nerve Block; Pain | 2020 |
Pharmacological Transection of Brain-Spinal Cord Communication Blocks Pain-Induced Hemorrhage and Locomotor Deficits after Spinal Cord Injury in Rats.
Topics: Anesthetics, Local; Animals; Brain; Hemorrhage; Lidocaine; Locomotion; Pain; Pain Measurement; Rats; | 2020 |
Management of diabetic foot ulcers: a 25% lidocaine topical cream formulation design, physicochemical and microbiological assessments.
Topics: Administration, Cutaneous; Anesthetics, Local; Chemistry, Pharmaceutical; Diabetic Foot; Drug Compou | 2020 |
Plating of clavicle fracture using the wide-awake technique.
Topics: Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Bone Plates; Buffers; Clavicle; Epinephrin | 2020 |
Reporting strategies and clinical outcome when using intravenous lidocaine in burns.
Topics: Analgesics, Opioid; Anesthetics, Local; Burns; Double-Blind Method; Humans; Lidocaine; Pain; Prospec | 2021 |
Lidocaine Versus Bupivacaine in the Treatment of Headache with Intranasal Sphenopalatine Nerve Block.
Topics: Adolescent; Adult; Anesthetics, Local; Bupivacaine; Cohort Studies; Female; Ganglia, Parasympathetic | 2020 |
Topical Cetacaine is probably more effective in preventing pain than benzocaine and an eutectic mixture of local anesthetic before palatal infiltration in children.
Topics: Administration, Topical; Anesthetics, Local; Benzalkonium Compounds; Benzocaine; Cetrimonium Compoun | 2020 |
Beyond lidocaine: selective voltage-gated sodium channel blockade for vaginal pain.
Topics: Female; Humans; Lidocaine; Nociception; Pain; Sodium; Sodium Channel Blockers; Voltage-Gated Sodium | 2021 |
Once again, less pain with articaine!
Topics: Anesthesia, Dental; Anesthetics, Local; Carticaine; Humans; Lidocaine; Pain | 2020 |
The success of using 2% lidocaine in pain removal during extraction of mandibular premolars: a prospective clinical study.
Topics: Anesthesia, Dental; Anesthetics, Local; Bicuspid; Carticaine; Double-Blind Method; Humans; Lidocaine | 2020 |
The Effectiveness of Jet (Needle-Free) Injector to Provide Anesthesia in Child Circumcision under Local Anesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Child; Child, Preschool; Humans; Injections, Jet; Lidocaine; | 2022 |
Continuous Intravenous Lidocaine Provides Effective Pain Control in a Palliative Child: A Case Report.
Topics: Administration, Intravenous; Child; Humans; Lidocaine; Pain; Pain Management | 2020 |
5% Lidocaine Hydrochloride Cream for Wound Pain Relief: A Multicentre Observational Study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Hum | 2022 |
Determinants of pain in advanced HCC patients recieving hepatic artery infusion chemotherapy.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesics; Anesthetics, Local; Antineoplastic Combined | 2021 |
Image-Guided Peripheral Nerve Cryoneurolysis for Pain Relief in Calciphylaxis.
Topics: Anesthetics, Local; Bupivacaine; Calciphylaxis; Cryosurgery; Humans; Lidocaine; Male; Middle Aged; N | 2020 |
[A Case of Abdominal Fullness Caused by a Retroperitoneal Bulky Tumor Treated with Epidural Analgesia].
Topics: Analgesia, Epidural; Analgesics, Opioid; Female; Humans; Lidocaine; Middle Aged; Morphine; Neoplasm | 2020 |
Did lidocaine indeed significantly contribute to the reduction of opioid consumption in the treatment of background pain after burns in this randomized controlled trial?
Topics: Analgesics, Opioid; Anesthetics, Local; Burns; Double-Blind Method; Humans; Lidocaine; Pain; Prospec | 2021 |
Add-on therapy of interfascial hydrodissection to trigger point injection for myofascial pain?
Topics: Humans; Lidocaine; Myofascial Pain Syndromes; Pain; Trigger Points | 2021 |
Propofol extravasation pain masked by lignocaine premedication.
Topics: Anesthetics, Intravenous; Humans; Lidocaine; Pain; Premedication; Propofol | 2021 |
Buffering Lidocaine 1%/ Epinephrine with Sodium Bicarbonate in a 3:1 Ratio Is as Effective and Less Painful than a 9:1 Ratio.
Topics: Anesthetics, Local; Double-Blind Method; Epinephrine; Humans; Lidocaine; Pain; Sodium Bicarbonate | 2021 |
Methylene blue induces an analgesic effect by significantly decreasing neural firing rates and improves pain behaviors in rats.
Topics: Action Potentials; Analgesics; Animals; Coloring Agents; Disease Models, Animal; Dose-Response Relat | 2021 |
Response to 'Effect of low-dose lidocaine on objective upper extremity strength and immediate pain relief following cervical interlaminar epidural injections: a double-blinded randomized controlled trial'.
Topics: Humans; Injections, Epidural; Lidocaine; Pain; Pain Management; Upper Extremity | 2021 |
Should lidocaine routinely be used to prevent pain on propofol injection during induction of general anaesthesia or sedation?
Topics: Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Humans; Lidocaine; Pain; Propofol | 2021 |
The Effect on Pain and Anxiety of Hot Pad Applied to Patients During Transrectal Prostate Biopsy.
Topics: Anesthetics, Local; Anxiety; Biopsy; Humans; Hyperthermia, Induced; Lidocaine; Male; Pain; Pain Meas | 2021 |
Tumescent local anesthesia versus general anesthesia for subcutaneous implantable cardioverter-defibrillator implantation.
Topics: Anesthesia, Local; Anesthetics, Local; Death, Sudden, Cardiac; Defibrillators, Implantable; Female; | 2021 |
Atractylodin Produces Antinociceptive Effect through a Long-Lasting TRPA1 Channel Activation.
Topics: Analgesics; Animals; Calcium; Calcium Channels; Furans; Ganglia, Spinal; HEK293 Cells; Humans; Isoth | 2021 |
Cannula for periocular eyelid lidocaine injection to prevent bruising.
Topics: Anesthetics, Local; Cannula; Eyelids; Humans; Lidocaine; Pain | 2023 |
10% lidocaine spray versus chlorhexidine, not placebo.
Topics: Anesthetics, Local; Chlorhexidine; Double-Blind Method; Humans; Lidocaine; Pain | 2022 |
Topical Lidocaine Reduces Vaccination Pain in Infants.
Topics: Anesthetics, Local; Double-Blind Method; Humans; Infant; Lidocaine; Pain; Pain Measurement; Vaccinat | 2017 |
Comparative antinociceptive effect of arachidonylcyclopropylamide, a cannabinoid 1 receptor agonist & lignocaine, a local anaesthetic agent, following direct intrawound administration in rats.
Topics: Analgesics; Animals; Arachidonic Acids; Humans; Lidocaine; Male; Pain; Pain Measurement; Rats; Recep | 2016 |
Transformation of the peripheral intravenous catheter placement experience in pediatrics.
Topics: Administration, Cutaneous; Adolescent; Age Factors; Anesthetics, Local; Catheterization, Peripheral; | 2017 |
Continuous serratus plane block in a patient with multiple rib fractures.
Topics: Amides; Anesthetics, Local; Fractures, Multiple; Humans; Intermediate Back Muscles; Lidocaine; Male; | 2017 |
Revisiting Mechanisms of Extraterritorial Allodynia.
Topics: Adenocarcinoma; Humans; Hyperalgesia; Lidocaine; Male; Middle Aged; Pain; Pain Threshold; Spinal Cor | 2017 |
Advanced multi-targeted composite biomaterial dressing for pain and infection control in chronic leg ulcers.
Topics: Anti-Bacterial Agents; Bandages; Biocompatible Materials; Carrageenan; Cells, Cultured; Humans; Hyal | 2017 |
Tumescent anesthesia for reducing pain, swelling, and ecchymosis during polycaprolactone filler injections in the face.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Cicatrix; Cosmetic Techniques; Dermal Fillers; Ecchymo | 2017 |
The antimicrobial activity of bupivacaine, lidocaine and mepivacaine against equine pathogens: An investigation of 40 bacterial isolates.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Anti-Bacterial Agents; Bacteria; Bupivacaine; Dose-R | 2017 |
Parallel, minimal needle-insertion technique for achieving a painless injection of local anesthetic.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Cohort Studies; Female; Humans; Inje | 2017 |
A novel anesthetic technique for palmar botulinum toxin injection.
Topics: Anesthesia; Anesthetics, Local; Botulinum Toxins, Type A; Hand; Humans; Hyperhidrosis; Injections; L | 2017 |
Layering of different materials to achieve optimal conditions for treatment of painful wounds.
Topics: Bandages; Biocompatible Materials; Cells, Cultured; Diclofenac; Fibroblasts; Humans; Lidocaine; Pain | 2017 |
BET 1: Lidocaine with propofol to reduce pain on injection.
Topics: Adult; Anesthetics, Local; Humans; Injections; Lidocaine; Male; Pain; Propofol | 2017 |
Lidocaine/ketorolac-loaded biodegradable nanofibrous anti-adhesive membranes that offer sustained pain relief for surgical wounds.
Topics: Adhesives; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biocompatible Mater | 2017 |
Comments on manuscript: Lidocaine gel vs lidocaine spray in reducing pain during insertion of the intrauterine contraceptive device.
Topics: Anesthetics, Local; Double-Blind Method; Female; Humans; Intrauterine Devices; Lidocaine; Pain | 2017 |
An Intraplantar Hypertonic Saline Assay in Mice for Rapid Screening of Analgesics.
Topics: Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; F | 2018 |
Effects of Extracorporeal Shock Wave-Mediated Transdermal Local Anesthetic Drug Delivery on Rat Caudal Nerves.
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Disease Models, Animal; Extracorporeal Shock | 2018 |
Topical anaesthesia reduces sensitivity of castration wounds in neonatal piglets.
Topics: Anesthesia, Local; Animal Welfare; Animals; Animals, Newborn; Lidocaine; Male; Orchiectomy; Pain; Sw | 2017 |
Comments on manuscript: Lidocaine for pain control during intrauterine device insertion.
Topics: Anesthetics, Local; Female; Humans; Intrauterine Devices; Lidocaine; Pain; Pain Management | 2018 |
Retrospective evaluation of the effects of periprostatic local anesthesia on recurrent prostate biopsy.
Topics: Aged; Anesthetics, Local; Biopsy; Case-Control Studies; Humans; Lidocaine; Male; Middle Aged; Nerve | 2017 |
Menthol reduces phototoxicity pain in a mouse model of photodynamic therapy.
Topics: Acrylamides; Animals; Animals, Newborn; Antipruritics; Bridged Bicyclo Compounds, Heterocyclic; Derm | 2018 |
Mucosal co-delivery of ketorolac and lidocaine using polymeric wafers for dental application.
Topics: Adolescent; Adult; Alginates; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Drug Deli | 2018 |
Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314.
Topics: Anesthetics, Local; Animals; Bacterial Toxins; Gene Knockdown Techniques; Lidocaine; Methicillin-Res | 2018 |
A Multi-Center, Open-Label, Prospective Study of Cannula Injection of Small-Particle Hyaluronic Acid Plus Lidocaine (SPHAL) for Lip Augmentation.
Topics: Adult; Aged; Anesthetics, Local; Cannula; Contusions; Dermal Fillers; Edema; Esthetics; Female; Huma | 2018 |
Authors' reply to letter to the editor: Lidocaine gel vs lidocaine spray in reducing pain during insertion of the intrauterine contraceptive device.
Topics: Anesthetics, Local; Double-Blind Method; Female; Humans; Intrauterine Devices; Lidocaine; Pain | 2018 |
Effectiveness of regional anaesthesia for treatment of facial and hand wounds by emergency physicians: A 9-month prospective study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anatomic Landmarks; Anesthesia, Conduction; Anesthetics, | 2018 |
A Comparison Between Upper Arm and Chest for Optimal Site of Totally Implanted Venous Access Ports in Patients with Female Breast Cancer.
Topics: Administration, Intravenous; Adult; Aged; Anesthetics, Local; Antineoplastic Agents; Breast Neoplasm | 2018 |
Metabotropic glutamate receptor subtype 7 in the dorsal striatum oppositely modulates pain in sham and neuropathic rats.
Topics: Animals; Benzhydryl Compounds; Benzoxazoles; Corpus Striatum; Glutamic Acid; Hyperalgesia; Lidocaine | 2018 |
Intravenous lidocaine before caesarean section.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Double-Blind Method; Female; Humans | 2018 |
Tetracaine Challenges Old Dogma for Emergency Department Management of Corneal Abrasion Pain and Beckons a Definitive Study.
Topics: Emergency Service, Hospital; Humans; Lidocaine; Pain; Tetracaine | 2018 |
Palatal infiltration of articaine probably reduces pain during extraction and increases patient satisfaction compared with placebo.
Topics: Anesthetics, Local; Carticaine; Humans; Lidocaine; Molar; Pain; Patient Satisfaction | 2018 |
Buffered local anesthetics reduce injection pain and provide anesthesia for up to 5 hours.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Female; Humans; Injections; Lidocaine; Male; Pain; Tim | 2018 |
In Lumbar Spinal Stenosis, Adding Corticosteroids to Lidocaine Epidural Injections Did Not Improve Pain or Function at 12 Months.
Topics: Adrenal Cortex Hormones; Anesthetics, Local; Humans; Injections, Epidural; Lidocaine; Pain; Spinal S | 2018 |
Pain Inhibits Pain: an Ascending-Descending Pain Modulation Pathway Linking Mesolimbic and Classical Descending Mechanisms.
Topics: Analgesia; Analgesics, Opioid; Animals; Benzazepines; Lidocaine; Male; Medulla Oblongata; Pain; Pain | 2019 |
Urethral instillations of clobetasol propionate and lidocaine: a promising treatment of urethral pain syndrome.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Clobetasol; Female; Glucocorti | 2016 |
Pain in the hand caused by a previously undescribed mechanism with possible relevance for understanding regional pain.
Topics: Acupuncture Points; Adult; Anesthetics, Local; Bupivacaine; Female; Hand; Humans; Injections, Intrav | 2018 |
Pain management for children needing laceration repair.
Topics: Administration, Cutaneous; Anesthetics, Local; Child; Drug Combinations; Epinephrine; Humans; Lacera | 2018 |
Comparison of antinociceptive effects of plain lidocaine versus lidocaine complexed with hydroxypropyl-β-cyclodextrin in animal models of acute and persistent orofacial pain.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Analgesics; Animals; Capsaicin; Carrageenan; Disease Models, Anim | 2019 |
Oral lidocaine for infant teething reclassified as Pharmacy only.
Topics: Administration, Oral; Drug and Narcotic Control; Humans; Infant; Lidocaine; Nonprescription Drugs; P | 2019 |
Beyond Opioids for Pain Management in Adult Critically Ill Patients.
Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Adult; Analgesia; Analgesics; Analgesics, Non-N | 2019 |
Analgesia for lumbar puncture in infants and children.
Topics: Adolescent; Analgesia; Anesthetics, Local; Child; Child, Preschool; Emergency Service, Hospital; Hum | 2019 |
Effect of perithyroidal lignocaine infusion (PLI) to pain experienced during high-intensity focused ultrasound (HIFU) ablation of benign thyroid nodules.
Topics: Anesthetics, Local; Body Mass Index; Demography; Female; High-Intensity Focused Ultrasound Ablation; | 2019 |
Commentary to: Prospective comparative study on the effects of lidocaine on urodynamic and sensory parameters in bladder-pain syndrome.
Topics: Humans; Lidocaine; Pain; Prospective Studies; Urodynamics | 2019 |
The Search for an Effective Therapy and Pain Relief for Oral Mucositis.
Topics: Antacids; Diphenhydramine; Doxepin; Humans; Lidocaine; Mouthwashes; Pain; Stomatitis | 2019 |
The Search for an Effective Therapy and Pain Relief for Oral Mucositis.
Topics: Antacids; Diphenhydramine; Doxepin; Humans; Lidocaine; Mouthwashes; Pain; Stomatitis | 2019 |
The Search for an Effective Therapy and Pain Relief for Oral Mucositis.
Topics: Antacids; Diphenhydramine; Doxepin; Humans; Lidocaine; Mouthwashes; Pain; Stomatitis | 2019 |
The Search for an Effective Therapy and Pain Relief for Oral Mucositis.
Topics: Antacids; Diphenhydramine; Doxepin; Humans; Lidocaine; Mouthwashes; Pain; Stomatitis | 2019 |
[Pain and distress responses of suckling piglets to injection and castration under local anaesthesia with procaine and lidocaine - Part 1: Cortisol, chromogranin A, wound healing, weights, losses].
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Animals, Suckling; Body Weight; Chromogranin A; Hand | 2019 |
The challenge of distinguishing pain from distress in young children.
Topics: Child; Child, Preschool; Double-Blind Method; Humans; Infant; Lidocaine; Nasal Sprays; Pain; Phenyle | 2019 |
Challenges of Remote Medical Care in South Sudan: Centipede Bites.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Arthropod Venoms; | 2019 |
Erythermalgia Involving the Face Alone: Two Case Reports.
Topics: Erythromelalgia; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Skin | 2019 |
Development and evaluation of a technique for spinal anaesthesia in broiler chickens.
Topics: Analysis of Variance; Anesthesia, Spinal; Anesthetics, Local; Animals; Chickens; Female; Interverteb | 2019 |
Effect of syringe size on severity of pain during local anesthesia administration.
Topics: Adult; Anesthetics, Local; Equipment Design; Female; Humans; Lidocaine; Male; Needles; Pain; Pain Me | 2019 |
Buffering the Suffering of Breast Lymphoscintigraphy.
Topics: Aged; Anesthetics, Local; Attitude of Health Personnel; Breast Neoplasms; Female; Humans; Injections | 2020 |
[Pain and distress response of suckling piglets to injection and castration under local anaesthesia with procaine and licocaine - Part 2: Defence behaviour, catecholamines, coordination of movements].
Topics: Anesthetics, Local; Animals; Animals, Suckling; Behavior, Animal; Catecholamines; Injections; Lidoca | 2019 |
Stability of a novel Lidocaine, Adrenaline and Tetracaine sterile thermosensitive gel: A ready-to-use formulation.
Topics: Anesthetics, Local; Chemistry, Pharmaceutical; Epinephrine; Gels; Lidocaine; Pain; Pain Measurement; | 2019 |
Comparing 2% lidocaine gel (Dispogel and Cathejell) in cystoscopy.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cystoscopy; Gels; Humans; Lidocaine; Male; Middle Aged; Pai | 2019 |
Two-step minipercutaneous ureterolithotripsy under multimodal analgesia for complicated impacted calculi in proximal ureter.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia, Local; Anesthetics, Local; Female; Humans; L | 2013 |
Local anaesthetic repair of uncomplicated paraumbilical hernia without sedation: peri-operative pain and patient satisfaction.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Body Mass Index; Bupivacaine; Clinical Competenc | 2013 |
Antihyperalgesic activity of a novel synthesized analogue of lidocaine in diabetic rats.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Diabetes Complications; | 2013 |
Lidocaine patch 5% for acute pain management.
Topics: Acute Pain; Administration, Cutaneous; Anesthetics, Local; Humans; Lidocaine; Pain; Pain Management | 2013 |
[Epidural pharmacotherapy in the treatment of the pain syndrome in osteochondrosis complicated by intervertebral discs protrusion of lumbar part of the vertebral column].
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Dexamethasone; Epidural Space | 2013 |
Use of ophthalmic lidocaine gel as an anesthetic for intravitreal injections.
Topics: Anesthetics, Local; Female; Gels; Humans; Intravitreal Injections; Lidocaine; Male; Ophthalmic Solut | 2013 |
Functional connectivity of the default mode network and its association with pain networks in irritable bowel patients assessed via lidocaine treatment.
Topics: Administration, Rectal; Adult; Anesthetics, Local; Data Interpretation, Statistical; Female; Functio | 2013 |
An alternative local anaesthesia technique to reduce pain in paediatric patients during needle insertion.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Child; Child, Pres | 2013 |
[Investigation of the influence of intracameral injection of domestic lidocaine on the corneal thickness during phacoemulsification of cataract].
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Anterior Chamber; Cataract; Cornea; Female; Humans; Hy | 2012 |
[Methaemoglobinaemia after using EMLA cream].
Topics: Analgesics; Anesthetics, Combined; Anesthetics, Local; Blood Gas Analysis; Female; Humans; Lidocaine | 2013 |
Activation of ERK signaling in rostral ventromedial medulla is dependent on afferent input from dorsal column pathway and contributes to acetic acid-induced visceral nociception.
Topics: Acetic Acid; Afferent Pathways; Anesthetics, Local; Animals; Butadienes; Enzyme Activation; Extracel | 2013 |
Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis?
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dental Pulp; Epinephrine; Female; Humans; Lidocaine; | 2013 |
Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis?
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dental Pulp; Epinephrine; Female; Humans; Lidocaine; | 2013 |
Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis?
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dental Pulp; Epinephrine; Female; Humans; Lidocaine; | 2013 |
Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis?
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dental Pulp; Epinephrine; Female; Humans; Lidocaine; | 2013 |
An open-label pilot study evaluating the effectiveness of the heated lidocaine/tetracaine patch for the treatment of pain associated with carpal tunnel syndrome.
Topics: Administration, Cutaneous; Adult; Carpal Tunnel Syndrome; Drug Combinations; Female; Hot Temperature | 2014 |
Re: Randomized clinical trial comparing effectiveness of intracorpus spongiosum block versus topical anesthesia for performing visual internal urethrotomy for urethral stricture disease.
Topics: Anesthesia, Local; Anesthetics, Local; Humans; Intraoperative Complications; Lidocaine; Male; Pain; | 2013 |
Factors that affect the efficacy of fluoroscopically guided selective spinal nerve root block in the treatment of radicular pain: a prospective cohort study.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Cohort St | 2013 |
[Evaluation of peripherally inserted central catheters in a pediatric population].
Topics: Adolescent; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Catheter-Related Infection | 2013 |
Unclear study methods still confusing readers despite CONSORT guidelines (e.g., lidocaine patch does relieve pain of covered rib fractures).
Topics: Case-Control Studies; Guideline Adherence; Humans; Lidocaine; Pain; Pain Measurement; Periodicals as | 2014 |
Qualification of fMRI as a biomarker for pain in anesthetized rats by comparison with behavioral response in conscious rats.
Topics: Anesthesia, General; Anesthetics, Local; Animals; Brain; Brain Mapping; Consciousness; Image Process | 2014 |
Expectation requires treatment to boost pain relief: an fMRI study.
Topics: Adult; Anesthetics, Local; Antipruritics; Brain; Capsaicin; Female; Humans; Image Processing, Comput | 2014 |
Reducing the pain of intramuscular benzathine penicillin injections in the rheumatic fever population of Counties Manukau District Health Board.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Local; Child; Child, Preschool; Fear; Female; | 2014 |
Reducing the pain of intramuscular benzathine penicillin injections in the rheumatic fever population of Counties Manukau District Health Board.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Local; Child; Child, Preschool; Fear; Female; | 2014 |
Reducing the pain of intramuscular benzathine penicillin injections in the rheumatic fever population of Counties Manukau District Health Board.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Local; Child; Child, Preschool; Fear; Female; | 2014 |
Reducing the pain of intramuscular benzathine penicillin injections in the rheumatic fever population of Counties Manukau District Health Board.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Local; Child; Child, Preschool; Fear; Female; | 2014 |
Pre-emptive penile ring block with sucrose analgesia reduces pain response to neonatal circumcision.
Topics: Analgesia; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Logistic Models; Male; Multivaria | 2014 |
Reply by the authors.
Topics: Anesthesia, Local; Anesthetics, Local; Humans; Intraoperative Complications; Lidocaine; Male; Pain; | 2013 |
Re: Bastab et al.: Randomized clinical trial comparing effectiveness of intracorpus spongiosum block versus topical anesthesia for performing visual internal urethrotomy for urethral stricture disease (Urology 2013;81:204-207).
Topics: Anesthesia, Local; Anesthetics, Local; Humans; Intraoperative Complications; Lidocaine; Male; Pain; | 2013 |
Lidocaine may be effective in alleviating physical symptoms in cancer patients.
Topics: Anesthetics, Local; Humans; Lidocaine; Neoplasms; Pain; Pain Management | 2014 |
Topical lidocaine-epinephrine-tetracaine is effective in reducing pain during laceration repair with tissue adhesive in children.
Topics: Anesthetics, Local; Epinephrine; Female; Humans; Lidocaine; Male; Pain; Tetracaine | 2014 |
Transretroperitoneal CT-guided embolization of growing internal iliac artery aneurysm after repair of abdominal aortic aneurysm: a transretroperitoneal approach with intramuscular lidocaine injection technique.
Topics: Aged, 80 and over; Anesthetics, Local; Aortic Aneurysm, Abdominal; Embolization, Therapeutic; Female | 2015 |
[Base in four types of lidocaine preparation (formulated in hospital)].
Topics: Acrylic Resins; Administration, Topical; Anesthetics, Local; Animals; Chemistry, Pharmaceutical; Fem | 2014 |
Reducing pain associated with arterial punctures for blood gas analysis.
Topics: Anesthetics, Local; Blood Gas Analysis; Female; Humans; Lidocaine; Male; Pain; Pain Measurement; Phl | 2014 |
Duloxetine in the treatment of burning mouth syndrome refractory to conventional treatment: A case report.
Topics: Aged; Analgesics; Burning Mouth Syndrome; Duloxetine Hydrochloride; Female; Humans; Lidocaine; Lingu | 2014 |
Is perioperative intravenous lidocaine for complex spine surgery a more complex issue?
Topics: Analgesics, Opioid; Female; Humans; Lidocaine; Male; Pain; Perioperative Care; Quality of Life; Spin | 2014 |
In reply.
Topics: Analgesics, Opioid; Female; Humans; Lidocaine; Male; Pain; Perioperative Care; Quality of Life; Spin | 2014 |
Step-up testing procedure for multiple comparisons with a control for a latent variable model with ordered categorical responses.
Topics: Algorithms; Clinical Trials as Topic; Computer Simulation; Data Interpretation, Statistical; Fentany | 2014 |
Centipede bite.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Allergic Agents; Anti-Inflammatory Agent | 2014 |
Use of 5% lidocaine medicated plasters for the treatment of pain in routine hospital practice: patient reported pain, functioning and satisfaction.
Topics: Administration, Cutaneous; Anesthetics, Local; Dosage Forms; Health Care Surveys; Hospitals, Teachin | 2014 |
Improving the local anesthesia experience for our patients.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Carticaine; Equipment Design | 2014 |
Evidence appraisal of Harman S, Zemek R, Duncan MJ, Ying Y, Petrcich W. Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children: a randomized controlled trial. CMAJ. 2013;185(13):E62
Topics: Anesthetics, Local; Epinephrine; Female; Humans; Lidocaine; Male; Pain; Tetracaine | 2014 |
Co-administration of memantine with epinephrine produces a marked peripheral action in intensifying and prolonging analgesia in response to local skin pinprick in rats.
Topics: Analgesics; Anesthetics, Combined; Anesthetics, Local; Animals; Epinephrine; Lidocaine; Male; Memant | 2014 |
Prospective double-blind preoperative pain clinic screening before microsurgical denervation of the spermatic cord in patients with testicular pain syndrome.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Bupivacaine; Denervation; Double-Blind Method; Humans; | 2014 |
Study of the anesthetic efficacy of inferior alveolar nerve block using articaine in irreversible pulpitis.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Carticaine; Epinephrine; Humans; Lidocain | 2014 |
LMX4 leads to poor IV dressing adherence.
Topics: Adhesiveness; Administration, Cutaneous; Anesthetics, Local; Bandages; Child; Humans; Infusions, Int | 2014 |
Lidocaine gel should be more effective in reducing urethral pain during urodynamic study in men: Re: Stav K, Taleb E, Sabler IM, Siegel YI, Beberashvili I, Zisman A. Liquid paraffin is superior to 2% lidocaine gel in reducing urethral pain during urodynam
Topics: Anesthetics, Local; Emollients; Humans; Lidocaine; Lubricants; Male; Mineral Oil; Pain; Urinary Cath | 2015 |
Healing of surgical castration wounds: a description and an evaluation of flunixin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cattle; Clonixin; Injections; Li | 2014 |
Pain and satisfaction during rigid cystoscopic ureteral stent removal: a preliminary study.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Cross-Sectional Studies; Cystoscopy; Device Removal; H | 2014 |
Carborane-derived local anesthetics are isomer dependent.
Topics: Anesthetics, Local; Animals; Area Under Curve; Binding Sites; Boranes; Catalysis; Catalytic Domain; | 2015 |
Cortisol and pain-related behavior in disbudded goat kids with and without cornual nerve block.
Topics: Anesthetics, Local; Animals; Female; Goats; Horns; Hydrocortisone; Lidocaine; Male; Motor Activity; | 2015 |
Coapplication of lidocaine and membrane-impermeable lidocaine derivative QX-222 produces divergent effects on evoked and spontaneous nociceptive behaviors in mice.
Topics: Analgesics; Animals; Behavior, Animal; Drug Combinations; Humans; Lidocaine; Mice; Nociception; Pain | 2014 |
Blue toe syndrome, ischemic pain treated with digital block.
Topics: Anesthetics, Local; Blue Toe Syndrome; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Pain | 2015 |
Lidocaine spray administration in transrectal ultrasound-guided prostate biopsy: five years of experience.
Topics: Aerosols; Aged; Anesthetics, Local; Biopsy, Needle; Humans; Image-Guided Biopsy; Lidocaine; Male; Mi | 2014 |
EN3427: a novel cationic aminoindane with long-acting local anesthetic properties.
Topics: Analgesia; Analgesics; Anesthesia; Anesthesia, Local; Anesthetics, Local; Animals; Drug Design; Inda | 2015 |
The Pronociceptive Effect of Paradoxical Sleep Deprivation in Rats: Evidence for a Role of Descending Pain Modulation Mechanisms.
Topics: Animals; Bicuculline; Lidocaine; Male; Morphine; Motor Activity; Nociception; Pain; Pain Measurement | 2016 |
Distinct neural representations of placebo and nocebo effects.
Topics: Adult; Anesthetics, Local; Capsaicin; Cerebral Cortex; Female; Hot Temperature; Humans; Lidocaine; M | 2015 |
The use of the needle-free jet injection system with buffered lidocaine device does not change intravenous placement success in children in the emergency department.
Topics: Adolescent; Catheterization; Child; Child, Preschool; Emergency Service, Hospital; Female; Humans; I | 2015 |
Anaesthesia changes perceived finger width but not finger length.
Topics: Adult; Analysis of Variance; Anesthesia; Anesthetics, Local; Dose-Response Relationship, Drug; Femal | 2015 |
Diagnostic accuracy of sentinel node identification is maintained with the addition of local lidocaine and subareolar radioactive colloid injection.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Breast Neoplasms; Female; Humans; Lidocaine; Mid | 2015 |
Co-application of lidocaine and QX-572 induces divergent pain behaviours in mice.
Topics: Anesthetics, Local; Animals; Freund's Adjuvant; Injections; Lidocaine; Male; Mice; Nerve Block; Pain | 2015 |
Potential of hydrogel-forming and dissolving microneedles for use in paediatric populations.
Topics: Administration, Cutaneous; Adolescent; Analgesics; Animals; Caffeine; Child; Female; Humans; Hydroge | 2015 |
Behavioral and neurochemical analysis of ongoing bone cancer pain in rats.
Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Stero | 2015 |
Trigger point injection reduces the pain of idiopathic intracranial hypotension.
Topics: Female; Humans; Intracranial Hypotension; Lidocaine; Middle Aged; Pain; Trigger Points | 2015 |
Fever, Genital Pain, and Genital Ulcers.
Topics: Anesthetics, Local; Anti-Inflammatory Agents; Child; Clobetasol; Diagnosis, Differential; Female; Fe | 2016 |
Intravenous Lidocaine Infusion to Treat Chemotherapy-Induced Peripheral Neuropathy.
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Humans; Hypesthesia; Infusions, Intravenous; Lidoca | 2015 |
Galanin-Mediated Behavioural Hyperalgesia from the Dorsomedial Nucleus of the Hypothalamus Involves Two Independent Descending Pronociceptive Pathways.
Topics: Animals; Arthritis; Behavior, Animal; Disease Models, Animal; Electrophysiology; Galanin; Glutamic A | 2015 |
Use of Lidocaine 2% Gel Does Not Reduce Pain during Flexible Cystoscopy and Is Not Cost-Effective.
Topics: Aged; Anesthetics, Local; Cost-Benefit Analysis; Cystoscopy; Drug Therapy, Combination; Female; Gels | 2015 |
Pain relief during minor procedures: a challenge for gynaecologists.
Topics: Anesthesia, Obstetrical; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Endometrium; Female; Human | 2015 |
[Transdermal Local Anesthetics].
Topics: Administration, Cutaneous; Anesthesia, Local; Anesthetics, Local; Humans; Lidocaine; Male; Pain; Pai | 2015 |
Delirium Associated With Lidocaine Patch Administration: A Case Presentation.
Topics: Analgesics; Anesthetics, Local; Delirium; Female; Humans; Lidocaine; Pain | 2016 |
Distinct TRPV1- and TRPA1-based mechanisms underlying enhancement of oral ulcerative mucositis-induced pain by 5-fluorouracil.
Topics: Acetanilides; Anesthetics, Local; Animals; Anti-Bacterial Agents; Antimetabolites; Carcinosarcoma; C | 2016 |
Ultrasound-guided block of selective branches of the brachial plexus for vascular access surgery in the forearm: a preliminary report.
Topics: Aged; Aged, 80 and over; Amides; Anesthetics, Combined; Anesthetics, Local; Arteriovenous Shunt, Sur | 2016 |
The traditional Japanese medicine hangeshashinto alleviates oral ulcer-induced pain in a rat model.
Topics: Acetic Acid; Administration, Topical; Analgesics; Animals; Disease Models, Animal; Drugs, Chinese He | 2016 |
The immediate effects of lidocaine iontophoresis using interferential current on pressure sense threshold and tactile sensation.
Topics: Administration, Cutaneous; Adolescent; Adult; Anesthetics, Local; Female; Humans; Iontophoresis; Lid | 2016 |
[COMPARATIVE EVALUATION OF CURRENT METHODS OF ANESTHESIA IN PERFORMANCE OF TRANSRECTAL PROSTATE BIOPSY].
Topics: Administration, Rectal; Aged; Analgesia; Anesthetics, Local; Dosage Forms; Humans; Image-Guided Biop | 2015 |
Functional characterization of a mouse model for central post-stroke pain.
Topics: Animals; Collagenases; Disease Models, Animal; Hyperalgesia; Kainic Acid; Lidocaine; Mice, Inbred C5 | 2016 |
Intractable seizures in a toddler after application of an over-the-counter local anesthetic cream.
Topics: Administration, Cutaneous; Anesthetics, Local; Bandages; Burns; Drug Overdose; Emergency Service, Ho | 2016 |
Sustained relief of pain from osteosynthesis surgery of rib fracture by using biodegradable lidocaine-eluting nanofibrous membranes.
Topics: Absorbable Implants; Anesthetics, Local; Animals; Lactic Acid; Lidocaine; Membranes, Artificial; Nan | 2016 |
Making Comfort Count: Using Quality Improvement to Promote Pediatric Procedural Pain Management.
Topics: Administration, Cutaneous; Anesthetics, Local; Child; Health Care Surveys; Health Knowledge, Attitud | 2016 |
Systemic QX-314 Reduces Bone Cancer Pain through Selective Inhibition of Transient Receptor Potential Vanilloid Subfamily 1-expressing Primary Afferents in Mice.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Bone Neoplasms; Cyclic AMP Response Element-Binding P | 2016 |
[Efficacy of periprostatic nerve block anesthesia for pain control in transrectal ultrasound- guided systematic prostate biopsy].
Topics: Biopsy; Humans; Lidocaine; Male; Nerve Block; Pain; Pain Management; Pain Measurement; Prostate; Pro | 2016 |
Hyaluron Filler Containing Lidocaine on a CPM Basis for Lip Augmentation: Reports from Practical Experience.
Topics: Adult; Anesthetics, Local; Attitude of Health Personnel; Cosmetic Techniques; Dermal Fillers; Drug C | 2016 |
[Effect of Kou Yan Qing Ke Li on the prevention and treatment of radiation-induced oral mucositis in patients with nasopharyngeal carcinoma].
Topics: Carcinoma; Humans; Lidocaine; Mouth Mucosa; Mouthwashes; Nasopharyngeal Carcinoma; Nasopharyngeal Ne | 2016 |
[Perception of pain in flexible cystoscopy using intraurethral lidocaine].
Topics: Administration, Topical; Aged; Anesthetics, Local; Cystoscopy; Humans; Lidocaine; Male; Middle Aged; | 2016 |
Lidocaine can reduce the pain of intra-osseous fluid infusion.
Topics: Double-Blind Method; Humans; Infusions, Intraosseous; Lidocaine; Pain; Pain Measurement | 2016 |
Effect of Vapocoolant on Pain During Peripheral Intravenous Cannulation.
Topics: Anesthetics, Local; Catheterization, Peripheral; Humans; Lidocaine; Pain; Pain Measurement | 2016 |
Intermittent urethral catheterisation: the reality of the lubricants and catheters in the clinical practice of a Brazilian service.
Topics: Adolescent; Adult; Ambulatory Care Facilities; Anesthetics, Local; Brazil; Catheters; Child; Equipme | 2016 |
The Use of Topical Lidocaine Gel During Intermaxillary Fixation Procedure.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Female; Fracture Fixation, Internal; Gels; Gingiva; Hu | 2016 |
A new technique for repeated biopsies of the mammary gland in dairy cows allotted to Latin-square design studies.
Topics: Anesthetics, Local; Animal Feed; Animals; Biopsy; Cattle; Diet; Female; Lactation; Lidocaine; Mammar | 2016 |
Application of ultrasound-guided selective sensory nerve block for the endovascular treatment of hemodialysis fistula in the forearm.
Topics: Anesthetics, Local; Angioplasty, Balloon; Arteriovenous Shunt, Surgical; Autonomic Nerve Block; Fore | 2016 |
Localized Sympathectomy Reduces Mechanical Hypersensitivity by Restoring Normal Immune Homeostasis in Rat Models of Inflammatory Pain.
Topics: Anesthetics, Local; Animals; Cytokines; Disease Models, Animal; Female; Ganglia, Spinal; Homeostasis | 2016 |
Parabrachial complex links pain transmission to descending pain modulation.
Topics: Action Potentials; Anesthetics, Local; Animals; Calcitonin Gene-Related Peptide; GABA-A Receptor Ago | 2016 |
Lidocaine controls pain and allows safe wound bed preparation and debridement of digital ulcers in systemic sclerosis: a retrospective study.
Topics: Aged; Anesthetics, Local; Debridement; Female; Fingers; Humans; Lidocaine; Male; Middle Aged; Pain; | 2017 |
Ultrasound-guided peripheral nerve blocks are useful for resections of malignant skin tumours on the leg.
Topics: Adult; Aged; Aged, 80 and over; Amides; Female; Femoral Nerve; Humans; Leg; Lidocaine; Male; Middle | 2017 |
Effects of two different local anaesthetic methods vs no anaesthesia on pain scores for intratympanic injections.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Dexamethasone; Female; Glucoco | 2016 |
CaMKIIα underlies spontaneous and evoked pain behaviors in Berkeley sickle cell transgenic mice.
Topics: Anemia, Sickle Cell; Anesthetics, Local; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein | 2016 |
The effectiveness of transforaminal epidural steroid injections on radicular pain, functionality, psychological status and sleep quality in patients with lumbar disc herniation.
Topics: Adult; Anesthetics, Local; Betamethasone; Female; Fluoroscopy; Glucocorticoids; Humans; Injections, | 2017 |
Pain Input Impairs Recovery after Spinal Cord Injury: Treatment with Lidocaine.
Topics: Anesthetics, Local; Animals; Disease Models, Animal; Lidocaine; Male; Pain; Rats; Rats, Sprague-Dawl | 2017 |
Cellular permeation of large molecules mediated by TRPM8 channels.
Topics: Anesthetics, Local; Animals; Cell Line; Ganglia, Spinal; Humans; Lidocaine; Nociceptors; Pain; Rats; | 2017 |
Drug-coated microneedles for rapid and painless local anesthesia.
Topics: Administration, Topical; Anesthetics, Local; Animals; Drug Delivery Systems; Drug Liberation; Lidoca | 2017 |
pH-sensitive niosomes: Effects on cytotoxicity and on inflammation and pain in murine models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; BALB 3T3 Cells; Cells, Cultured; Disease Models, A | 2017 |
Continuous Lidocaine Infusion as Adjunctive Analgesia in Intensive Care Unit Patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesia; Anesthetics, Local; Drug Administration Routes; Female; H | 2017 |
Lidocaine gel vs lidocaine spray in reducing pain during insertion of the intrauterine contraceptive device.
Topics: Administration, Topical; Adult; Anesthetics, Local; Contraception; Female; Humans; Intrauterine Devi | 2017 |
Increasing ED Use of Jet Injection of Lidocaine for IV-Related Pain Management.
Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Emergency Service, Hospital; Female; Humans | 2017 |
Warmed local anesthetic for dermatologic surgery.
Topics: Anesthesia, Local; Anesthetics, Local; Dermatologic Surgical Procedures; Dermatology; Heating; Human | 2008 |
[Value of nitrous oxide-oxygen mixture (Entonox) in transrectal prostate biopsies].
Topics: Administration, Inhalation; Administration, Rectal; Aged; Anxiety; Biopsy; Gels; Humans; Lidocaine; | 2008 |
A comparison of injection pain with articaine with adrenaline, prilocaine with phenylpressin and lidocaine with adrenaline.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Carticaine; Drug Therapy, Combinatio | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.
Topics: Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Humans; Lidocaine; Pain; P | 2008 |
Is topical lignocaine for pain relief in acute otitis media really effective?
Topics: Acute Disease; Administration, Topical; Anesthetics, Local; Child; Humans; Lidocaine; Otitis Media; | 2008 |
[What is the place of topical analgesia in neuropathic pain?].
Topics: Administration, Topical; Analgesia; Analgesics; Anesthetics, Local; Humans; Lidocaine; Nervous Syste | 2008 |
Brain nociceptive imaging in rats using (18)f-fluorodeoxyglucose small-animal positron emission tomography.
Topics: Analgesics; Analysis of Variance; Animals; Brain; Fluorodeoxyglucose F18; Formaldehyde; Functional L | 2008 |
Relieving the pain of sentinel lymph node biopsy tracer injection.
Topics: Administration, Cutaneous; Anesthetics, Combined; Anesthetics, Local; Breast Neoplasms; Clinical Nur | 2008 |
Low risk of postinflammatory hyperpigmentation in skin types 4 and 5 after treatment with fractional CO2 laser device.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Dermatitis, Phototoxic; Female; Humans; Hyperpigmentat | 2008 |
Nociceptive behavior induced by mustard oil injection into the temporomandibular joint is blocked by a peripheral non-opioid analgesic and a central opioid analgesic.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, | 2009 |
Evaluation of dressings used with local anaesthetic cream and for peripheral venous cannulation.
Topics: Administration, Cutaneous; Anesthetics, Local; Attitude of Health Personnel; Catheterization, Periph | 2008 |
Neonatal pain relief and the Helsinki Declaration.
Topics: Biomedical Research; Circumcision, Male; Ethics Committees, Research; Helsinki Declaration; Humans; | 2008 |
The effect of intravenous lidocaine on brain activation during non-noxious and acute noxious stimulation of the forepaw: a functional magnetic resonance imaging study in the rat.
Topics: Anesthetics, Local; Animals; Brain; Brain Mapping; Disease Models, Animal; Electric Stimulation; Fem | 2009 |
Differential diagnosis of seizure associated with topical lidocaine in a patient with vestibulodynia.
Topics: Administration, Topical; Anesthetics, Local; Diagnosis, Differential; Female; Humans; Lidocaine; Mid | 2009 |
How to make screening mammography less uncomfortable.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen | 2008 |
Digital block anesthesia.
Topics: Aged; Anesthetics, Local; Epinephrine; Female; Fingers; Humans; Injections, Subcutaneous; Lidocaine; | 2009 |
Characteristics of L3 nerve root radiculopathy.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Decompression, Surgical; Disk | 2009 |
Thermal effect of sonophoresis for accelerating the analgesic effect of local anesthetics on rat tail nerve.
Topics: Analgesia; Anesthesia, Conduction; Anesthesia, Local; Anesthetics, Local; Animals; Hot Temperature; | 2008 |
Noradrenergic neurons in the locus coeruleus contribute to neuropathic pain.
Topics: Anesthetics, Local; Animals; Antibodies, Monoclonal; Cyclic AMP Response Element-Binding Protein; Im | 2009 |
Lidocaine injection into the rat dorsal root ganglion causes neuroinflammation.
Topics: Anesthetics, Local; Animals; CD11b Antigen; Ganglia, Spinal; Glial Fibrillary Acidic Protein; Hypera | 2009 |
Continuous epidural block of the cervical vertebrae for cervicogenic headache.
Topics: Adult; Aged; Anesthesia, Epidural; Cervical Vertebrae; Dexamethasone; Female; Humans; Lidocaine; Mal | 2009 |
Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Female; Humans; Injections, Intralesional; Kel | 2009 |
Effects of local anesthetic and a nonsteroidal antiinflammatory drug on pain responses of dairy calves to hot-iron dehorning.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cattle; Dair | 2009 |
Is Intrathecal lidocaine administration risk-free in rats with neuropathic pain? Reply to [Effects of intrathecal lidocaine on hyperalgesia and allodynia following chronic constriction injury in rats. Eur J Pain 13 (2009) 130-137].
Topics: Anesthetics, Local; Animals; Constriction, Pathologic; Cytokines; Dinoprostone; Hyperalgesia; Inject | 2009 |
Antinociceptive effects of systemic lidocaine: involvement of the spinal glycinergic system.
Topics: Analgesics; Animals; Binding Sites; Glycine; Glycine Agents; Lidocaine; Organophosphonates; Pain; Qu | 2009 |
Safe and less painful injection of triamcenolone acetonide into a keloid--a technique.
Topics: Anesthetics, Local; Bupivacaine; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Lidocai | 2010 |
[Pain during transrectal ultrasound guided needle biopsy of the prostate: comparison of the use or not of lidocaine gel].
Topics: Aged; Anesthetics, Local; Biopsy, Needle; Gels; Humans; Lidocaine; Male; Pain; Prospective Studies; | 2009 |
The behavioral assessment and alleviation of pain associated with castration in beef calves treated with flunixin meglumine and caudal lidocaine epidural anesthesia with epinephrine.
Topics: Anesthesia, Caudal; Anesthesia, Epidural; Anesthetics, Combined; Animals; Behavior, Animal; Cattle; | 2009 |
What stands in the way of treating palmar hyperhidrosis as effectively as axillary hyperhidrosis with botulinum toxin type A.
Topics: Administration, Cutaneous; Anesthesia, Local; Anesthetics, Local; Antibodies, Bacterial; Axilla; Bot | 2009 |
Pain level and anal discomfort during transrectal ultrasound for guided prostate biopsy. Does intrarectal administration of local anesthetic before periprostatic anesthesia makes any difference?
Topics: Administration, Rectal; Aged; Anesthesia, Local; Anesthetics, Local; Anus Diseases; Biopsy; Humans; | 2009 |
Use of lidocaine plaster for testicular pain.
Topics: Administration, Topical; Bandages; Humans; Lidocaine; Male; Middle Aged; Orchiectomy; Pain; Testicul | 2009 |
Comment from the editor on Lambertz et al in the September 2008 issue.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Lidocaine; Mammogra | 2009 |
Assessment of the production of analgesia induced by application of a rubber ring or local anaesthetic to the antler pedicle of yearling stags.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Antlers; Deer; Electric Stimulation; Lidocaine; Male | 2009 |
Inhibitory effect of lidocaine on pain and itch using formalin-induced nociception and 5'-guanidinonaltrindole-induced scratching models in mice: behavioral and neuroanatomical evidence.
Topics: Animals; Behavior, Animal; Formaldehyde; Gene Expression Regulation; Guanidines; Lidocaine; Male; Mi | 2009 |
fMRI investigation of the effect of local and systemic lidocaine on noxious electrical stimulation-induced activation in spinal cord.
Topics: Anesthetics, Local; Animals; Blood Pressure; Disease Models, Animal; Drug Administration Routes; Ele | 2009 |
Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Chronic Disease; Cold Temperature; Disease Models | 2010 |
Topical anaesthesia in children: reducing the need for specialty referral.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Local; Child; Child Welfare; Child, Prescho | 2010 |
[Radial nerve block for implantation of radial catheter].
Topics: Anesthetics, Local; Catheterization; Catheters, Indwelling; Humans; Lidocaine; Lidocaine, Prilocaine | 2009 |
Sentinel-lymph-node biopsy for breast cancer: the story is not yet over.
Topics: Anesthetics, Local; Breast Neoplasms; Drug Combinations; Female; Humans; Injections, Intradermal; Li | 2009 |
Pain control after cryotherapy.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Child; Cryotherapy; Humans; Lidocaine; Liposom | 2009 |
Topical lidocaine and the effect on enoxaparin absorption in children: a pilot study.
Topics: Absorption; Administration, Topical; Anesthetics, Local; Child; Child, Preschool; Clinical Protocols | 2010 |
Antinociception by motor cortex stimulation in the neuropathic rat: does the locus coeruleus play a role?
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; | 2010 |
The combined use of forced cold air and topical anesthetic cream for analgesia during the treatment of palmar hyperhydrosis with botulinum toxin injections.
Topics: Adult; Anesthetics, Local; Botulinum Toxins, Type A; Cold Temperature; Female; Follow-Up Studies; Ha | 2009 |
Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children.
Topics: Administration, Cutaneous; Administration, Inhalation; Adolescent; Anesthetics; Anti-Dyskinesia Agen | 2009 |
Combined use of infraorbital and external nasal nerve blocks for effective perioperative pain control during and after cleft lip repair.
Topics: Adolescent; Adult; Anesthetics, Local; Cleft Lip; Female; Humans; Infant; Lidocaine; Lidocaine, Pril | 2009 |
Ultrasound-aided unilateral epidural block for single lower-extremity pain.
Topics: Adult; Aged; Analgesia, Epidural; Anesthetics, Local; Arthroscopy; Epidural Space; Female; Fluorosco | 2009 |
Minimizing pain, maximizing comfort: a new technique for facial filler injections.
Topics: Anesthetics, Local; Biocompatible Materials; Cosmetic Techniques; Face; Humans; Hyaluronic Acid; Inj | 2009 |
The effects of some permeability enhancers on the percutaneous absorption of lidocaine.
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Cyclohexane Monoterpenes; Cyclohexanols; Cyc | 2010 |
Coupled obturator neurotomies and lidocaine intrathecal infusion to treat bilateral adductor spasticity and drug-refractory pain.
Topics: Adult; Anesthetics, Local; Cerebral Palsy; Female; Fetal Hypoxia; Follow-Up Studies; Humans; Infusio | 2010 |
Diphenidol inhibited sodium currents and produced spinal anesthesia.
Topics: Anesthetics, Local; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Lidocaine; Male; Me | 2010 |
[Our experiences in chronic benign pain by injecting local anaesthetic into scars].
Topics: Adult; Aged; Anesthetics, Local; Chronic Disease; Cicatrix; Female; Humans; Injections, Intralesiona | 2009 |
Selectively targeting pain in the trigeminal system.
Topics: Action Potentials; Analysis of Variance; Anesthetics, Local; Animals; Capsaicin; Electric Stimulatio | 2010 |
Minimizing pain during vasectomy: the mini-needle anesthetic technique.
Topics: Adult; Anesthetics, Local; Humans; Lidocaine; Male; Middle Aged; Needles; Pain; Pain Measurement; Pr | 2010 |
Effects of local tramadol administration on peripheral glutamate-induced nociceptive behaviour in mice.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Female; Foot; Glu | 2010 |
The parabrachial nucleus is a critical link in the transmission of short latency nociceptive information to midbrain dopaminergic neurons.
Topics: Anesthetics, Local; Animals; Dopamine; Electric Stimulation; Electrophysiology; Female; GABA-A Recep | 2010 |
Case reports: management of intractable upper extremity pain with continuous subarachnoid block at the low cervical level without impairment of upper extremity function.
Topics: Analgesics, Opioid; Anesthetics, Local; Cervical Vertebrae; Fatal Outcome; Humans; Lidocaine; Male; | 2010 |
Topical anaesthesia alleviates short-term pain of castration and tail docking in lambs.
Topics: Anesthesia, Local; Animal Welfare; Animals; Animals, Newborn; Behavior, Animal; Bupivacaine; Castrat | 2010 |
The safety of flexible fibre-optic bronchoscopy and proceduralist-administered sedation: a tertiary referral centre experience.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Bronchoscopy; Conscious Sedation; Dyspnea; Femal | 2012 |
Usage of lidocaine-prilocaine cream in the treatment of postburn pain in pediatric patients.
Topics: Administration, Oral; Administration, Topical; Adolescent; Anesthetics, Local; Burns; Child; Female; | 2010 |
Modified impingement test can predict the level of pain reduction after rotator cuff repair.
Topics: Adult; Aged; Aged, 80 and over; Arthroscopy; Cohort Studies; Female; Humans; Lidocaine; Male; Middle | 2010 |
Pain reduction in children during port-à-cath catheter puncture using local anaesthesia with EMLA™.
Topics: Adolescent; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; Cross-Over Stu | 2010 |
In vivo priming and ex vivo activation of equine neutrophils in black walnut extract-induced equine laminitis is not attenuated by systemic lidocaine administration.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; CD13 Antigens; CD18 Antigens; | 2010 |
Luminal serotonin time-dependently modulates vagal afferent driven antinociception in response to colorectal distention in rats.
Topics: Afferent Pathways; Analgesics; Animals; Capsaicin; Colon; Dilatation, Pathologic; Food Hypersensitiv | 2011 |
Using lidocaine as an additional topical local anesthetic agent in gynecological procedures.
Topics: Administration, Topical; Anesthesia, Local; Anesthesia, Obstetrical; Anesthetics, Local; Drug Therap | 2010 |
Treatment satisfaction in osteoarthritis and chronic low back pain: the role of pain, physical and emotional functioning, sleep, and adverse events.
Topics: Anesthetics, Local; Chronic Disease; Clinical Trials as Topic; Female; Humans; Lidocaine; Low Back P | 2011 |
Re: Tomlinson PJ, Field J. Warm or refrigerated local anaesthetic for open carpal tunnel release: a single blind randomized controlled study. J Hand Surg Eur. 2010, 35: 232-3.
Topics: Anesthetics, Local; Bupivacaine; Drug Combinations; Epinephrine; Humans; Lidocaine; Pain; Temperatur | 2010 |
Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Chin; Cranial Nerve Injuries; Female; Gingiva; H | 2010 |
Case report: computed tomography scan-guided Gasserian ganglion injection of dexamethasone and lidocaine for the treatment of recalcitrant pain associated with herpes simplex type 1 infection of the ophthalmic division of the trigeminal nerve.
Topics: Adolescent; Dexamethasone; Follow-Up Studies; Herpes Simplex; Herpesvirus 1, Human; Humans; Lidocain | 2011 |
Spotting the pain in fibromyalgia syndrome--widespread effects of local pain therapy.
Topics: Anesthetics, Local; Arthralgia; Facial Pain; Fibromyalgia; Humans; Lidocaine; Pain; Syndrome; Treatm | 2011 |
Anesthesia for ritual circumcision in neonates.
Topics: Anesthesia; Anesthetics, Local; Ceremonial Behavior; Circumcision, Male; Humans; Infant, Newborn; Is | 2010 |
Lidocaine reduces the transition to slow inactivation in Na(v)1.7 voltage-gated sodium channels.
Topics: Action Potentials; Anesthetics, Local; Cells, Cultured; HEK293 Cells; Humans; Lidocaine; Mutation; N | 2011 |
The use of topical lidocaine to reduce pain during repetitive transcranial magnetic stimulation for the treatment of depression.
Topics: Adult; Aged; Anesthetics, Local; Depression; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Tra | 2011 |
Pain intervention for infant lumbar puncture in the emergency department: physician practice and beliefs.
Topics: Analgesia; Anesthesia; Anesthetics, Local; Attitude of Health Personnel; Emergency Medicine; Emergen | 2011 |
Comparison between lidocaine and glyceryl trinitrate ointment for perianal-intrarectal local anesthesia before transrectal ultrasonography-guided prostate biopsy: a placebo-controlled trial.
Topics: Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; Gels; Humans; Lidocaine; Male; Nitroglycerin; | 2011 |
Development, characterization, and in vitro and in vivo evaluation of benzocaine- and lidocaine-loaded nanostructrured lipid carriers.
Topics: Analgesics; Anesthetics, Local; Animals; Benzocaine; Drug Carriers; Humans; Lidocaine; Lipids; Male; | 2011 |
Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review.
Topics: Analgesics; Animals; Drug Delivery Systems; Lidocaine; Male; Nociceptors; Pain; Rats; Sensory Recept | 2011 |
Long buccal nerve block injection pain in patients with irreversible pulpitis.
Topics: Adolescent; Adult; Age Factors; Aged; Anesthetics, Local; Benzocaine; Cheek; Epinephrine; Female; Hu | 2011 |
Nucleus accumbens facilitates nociception.
Topics: Analysis of Variance; Animals; Electrodes, Implanted; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injection | 2011 |
Judging pain sensitivity with subcutaneous lidocaine injections.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Anxiety; Behavior; Female; H | 2011 |
Painful traumatic neuroma of the tongue treated with serial alcohol injections.
Topics: Aged; Amines; Analgesics; Anesthetics, Local; Central Nervous System Depressants; Cyclohexanecarboxy | 2011 |
Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Site | 2011 |
Size of the transrectal ultrasound probe makes no difference in pain perception during TRUS-Bx under adequate local anesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Biopsy; Humans; Lidocaine; Male; Pain; Pain Measurement; Perc | 2012 |
Effect of local anaesthesia and/or analgesia on pain responses induced by piglet castration.
Topics: Analgesia; Anesthesia, Local; Anesthetics, Local; Animal Welfare; Animals; Animals, Newborn; Anti-In | 2011 |
Intraosseous catheter placement in children.
Topics: Adult; Analgesics, Opioid; Child; Humans; Infusions, Intraosseous; Lidocaine; Pain | 2011 |
Intravenous lidocaine for acute pain treatment.
Topics: Anesthetics, Local; Humans; Infusions, Intravenous; Lidocaine; Pain | 2011 |
Lidocaine patches reduce pain in trauma patients with rib fractures.
Topics: Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Oregon; Pain; Retrospective Studie | 2011 |
Long buccal nerve block: a previously unreported complication.
Topics: Anesthetics, Local; Arteries; Cheek; Epinephrine; Eyelids; Female; Humans; Lidocaine; Lip; Middle Ag | 2011 |
Pain and abortion.
Topics: Abortion, Induced; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Lidocaine; Pain; Pre | 2011 |
Benefits of adding lidocaine to a hyaluronic gel - Stylage® M.
Topics: Adult; Aged; Anesthetics, Local; Dermatologic Agents; Drug Combinations; Esthetics; Female; Humans; | 2011 |
Conscious sedation or general anaesthetic for intramuscular botulinum toxin injections in children - a two centre cross-sectional prospective audit.
Topics: Botulinum Toxins, Type A; Cerebral Palsy; Female; Humans; Lidocaine; Male; Nitrous Oxide; Pain; Para | 2012 |
Stimulation of the occipital or retrosplenial cortex reduces incision pain in rats.
Topics: Analgesics; Animals; Atropine; Cerebral Cortex; Electric Stimulation; Lidocaine; Male; Methysergide; | 2011 |
Atraumatic care: EMLA cream and application of heat to facilitate peripheral venous cannulation in children.
Topics: Anesthetics, Local; Child; Female; Humans; Hyperthermia, Induced; Lidocaine; Lidocaine, Prilocaine D | 2009 |
The use of lignocaine gel as a shaving gel for facial burns.
Topics: Anesthetics, Local; Burns; Facial Injuries; Gels; Hair Removal; Humans; Lidocaine; Male; Pain | 2012 |
How does topical lidocaine relieve pain?
Topics: Anesthetics, Local; Female; Humans; Lidocaine; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyeli | 2012 |
Care to relieve pain-stress in preterm newborns.
Topics: Anesthetics, Local; Female; Humans; Infant, Newborn; Infant, Premature; Lidocaine; Lidocaine, Priloc | 2011 |
Variation of pain and vasomotor responses evoked by intramuscular infusion of hypertonic saline in human subjects: influence of gender and its potential neural mechanisms.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Local; Dose-Response Relationship, Drug; Femal | 2012 |
Predictors of pain during and the day after corticosteroid injection for idiopathic trigger finger.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Cohort Studies; Dexamethasone; Female; Glucocort | 2012 |
Intravenous lidocaine for management of wound care pain.
Topics: Analgesics, Opioid; Female; Humans; Lidocaine; Male; Neoplasms; Pain; Pain Measurement | 2012 |
Relief of palatal injection pain by liposome-encapsulated 2% lignocaine prepared by ultrasonic dental scaler.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Benzocaine; Female; Humans; Injections; Lidocaine; Li | 2012 |
Retrosplenial cortex is involved in analgesia induced by 2- but not 100-Hz electroacupuncture in the rat tail-flick test.
Topics: Acupuncture Points; Analgesia; Animals; Cerebral Cortex; Electric Stimulation; Electroacupuncture; L | 2012 |
Afferent drive elicits ongoing pain in a model of advanced osteoarthritis.
Topics: Afferent Pathways; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, In | 2012 |
US-guided femoral and sciatic nerve blocks for analgesia during endovenous laser ablation.
Topics: Adult; Aged; Analgesia; Cohort Studies; Endovascular Procedures; Female; Femoral Nerve; Humans; Lase | 2013 |
Safety and acceptance of non-sedated upper gastrointestinal endoscopy: a prospective observational study.
Topics: Adult; Analysis of Variance; Anesthetics, Local; Endoscopy, Digestive System; Feasibility Studies; F | 2012 |
How does the lidocaine patch (5%) relieve pain?
Topics: Administration, Cutaneous; Analgesia; Anesthetics, Local; Humans; Lidocaine; Pain | 2012 |
Minimizing injection pain in local anesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Buffers; Equipment Design; Humans; Hydrogen-Ion Concentration | 2012 |
Hyperalgesia by low doses of the local anesthetic lidocaine involves cannabinoid signaling: an fMRI study in mice.
Topics: Anesthetics, Local; Animals; Cannabinoids; Disease Models, Animal; Female; Hyperalgesia; Lidocaine; | 2012 |
The use of subcutaneous infusion tumescent anesthesia in photodynamic therapy pain control.
Topics: Amides; Anesthesia, Local; Anesthetics, Local; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Chi | 2012 |
Non-surgical therapy for bilateral glossopharyngeal neuralgia caused by Eagle's syndrome, diagnosed by three-dimensional computed tomography: a case report.
Topics: Aged; Amines; Analgesics; Anesthetics, Local; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobu | 2012 |
Conscious sedation or general anaesthetic for intramuscular botulinum toxin injections in children - a two centre cross-sectional prospective audit.
Topics: Botulinum Toxins, Type A; Cerebral Palsy; Female; Humans; Lidocaine; Male; Nitrous Oxide; Pain; Para | 2013 |
Eutectic mixture of local anaesthetics (EMLA) 5% cream as a primary dressing on a painful lower leg ulcer.
Topics: Analgesics; Bandages; Drug Therapy, Combination; Female; Humans; Lidocaine; Lidocaine, Prilocaine Dr | 2012 |
A comparison of articaine 4% and lignocaine 2% in block and infiltration analgesia in children.
Topics: Adolescent; Anesthesia, Dental; Anesthetics, Local; Australia; Carticaine; Child; Dental Care for Ch | 2012 |
Cross-over study of topical anaesthesia with tetracaine solution for transoral rigid laryngoscopy.
Topics: Adult; Anesthesia, Local; Cross-Over Studies; Female; Humans; Laryngeal Diseases; Laryngoscopy; Lido | 2012 |
Evaluation of EMLA cream for preventing pain during tattooing of rabbits: changes in physiological, behavioural and facial expression responses.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Cross-Over Studies; Face; Lidocaine; Lidocaine, Prilo | 2012 |
Commentary: A prospective comparison between neutralizing the pH of 1% lidocaine with epinephrine (buffering) and pre-operative skin cooling in reducing the pain of infiltration of local anesthetic.
Topics: Anesthetics, Local; Buffers; Cryotherapy; Epinephrine; Humans; Lidocaine; Pain; Sodium Bicarbonate | 2012 |
Minimizing injection pain.
Topics: Anesthetics, Local; Benzyl Alcohol; Drug Combinations; Eye Injuries, Penetrating; Humans; Injections | 2012 |
[Efficacy and safety of lidocaine hydrochloride jelly for the treatment of pain caused by breast cancer metastases to the skin].
Topics: Adult; Breast Neoplasms; Female; Gels; Humans; Lidocaine; Middle Aged; Pain; Skin Neoplasms | 2012 |
Does pain score in response to a standardized subcutaneous local anesthetic injection predict epidural steroid injection outcomes in patients with lumbosacral radiculopathy? A prospective correlational study.
Topics: Adult; Aged; Anesthetics, Local; Female; Glucocorticoids; Humans; Injections, Epidural; Injections, | 2013 |
Frequency and intensity of pain related to thyroid nodule fine-needle aspiration cytology.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care Facilities; | 2013 |
Effects of adding alfentanil or atracurium to lidocaine solution for intravenous regional anaesthesia.
Topics: Adult; Alfentanil; Analysis of Variance; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetic | 2002 |
Safety, tolerability, and efficacy of iontophoresis with lidocaine for dermal anesthesia in ED pediatric patients.
Topics: Administration, Cutaneous; Anesthesia; Anesthetics, Local; Child; Child, Preschool; Emergency Servic | 2002 |
Lidocaine patch 5% and the management of chronic pain.
Topics: Administration, Cutaneous; Anesthetics, Local; Chronic Disease; Humans; Lidocaine; Pain; Primary Hea | 2002 |
A new method of continuous maxillary nerve block with an indwelling catheter.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Lo | 2002 |
[New indication for EMLA creme. Significant reduction of pain in mechanical would debridement].
Topics: Anesthesia, Local; Anesthetics, Local; Debridement; Humans; Lidocaine; Lidocaine, Prilocaine Drug Co | 2002 |
Continuous lidocaine infusion for the relief of refractory malignant pain in a terminally ill pediatric cancer patient.
Topics: Analgesics, Opioid; Child, Preschool; Female; Humans; Injections, Spinal; Lidocaine; Neoplasm Metast | 2002 |
Combined sphenopalatine ganglion and mandibular nerve, neurolytic block for pain due to advanced head and neck cancer.
Topics: Adult; Anesthetics, Local; Carcinoma; Fatal Outcome; Humans; Lidocaine; Male; Mouth Neoplasms; Nerve | 2002 |
Lidocaine transdermal--Vyteris.
Topics: Administration, Cutaneous; Anesthetics, Local; Clinical Trials, Phase III as Topic; Drug Delivery Sy | 2002 |
Lumbar spinal cord stimulation for cervical-originated central pain: a case report.
Topics: Acetates; Amines; Antidepressive Agents, Tricyclic; Cervical Vertebrae; Cyclohexanecarboxylic Acids; | 2002 |
Effects of analgesia of the distal interphalangeal joint and navicular bursa on experimental lameness caused by solar pain in horses.
Topics: Analgesia; Anesthetics, Local; Animals; Breeding; Bursa, Synovial; Foot Diseases; Gait; Hoof and Cla | 2002 |
Comparison of lidocaine and compression for velvet antler analgesia in wapiti.
Topics: Anesthetics, Local; Animals; Antlers; Behavior, Animal; Blood Pressure; Deer; Heart Rate; Hydrocorti | 2002 |
Intrathecal lidocaine reverses tactile allodynia caused by nerve injuries and potentiates the antiallodynic effect of the COX inhibitor ketorolac.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Dose-Response Relationship | 2003 |
Skin analgesia with lidocaine tape prior to epidural blockade.
Topics: Administration, Cutaneous; Analgesia; Analgesia, Epidural; Anesthetics, Local; Humans; Lidocaine; Pa | 2003 |
Lidocaine toxicity during frequent viscous lidocaine use for painful tongue ulcer.
Topics: Administration, Oral; Adult; Anesthetics, Local; Drug Administration Schedule; Humans; Lidocaine; Ma | 2002 |
Lidocaine toxicity during frequent viscous lidocaine use for painful tongue ulcer.
Topics: Administration, Oral; Adult; Anesthetics, Local; Drug Administration Schedule; Humans; Lidocaine; Ma | 2002 |
Lidocaine toxicity during frequent viscous lidocaine use for painful tongue ulcer.
Topics: Administration, Oral; Adult; Anesthetics, Local; Drug Administration Schedule; Humans; Lidocaine; Ma | 2002 |
Lidocaine toxicity during frequent viscous lidocaine use for painful tongue ulcer.
Topics: Administration, Oral; Adult; Anesthetics, Local; Drug Administration Schedule; Humans; Lidocaine; Ma | 2002 |
Use of lidocaine spray for pain relief and improved quality of life in terminally ill cancer patients.
Topics: Administration, Topical; Anesthetics, Local; Deglutition Disorders; Head and Neck Neoplasms; Humans; | 2002 |
A dissociative change in the efficacy of supraspinal versus spinal morphine in the neuropathic rat.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Respons | 2003 |
Submucous infiltration of betamethasone and lidocaine in the treatment of vulvar vestibulitis.
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Betamethasone; Female; Humans; Lidocaine; Pain; | 2003 |
Centrally mediated reflex vasodilation in the gingiva induced by painful tooth-pulp stimulation in sympathectomized human subjects.
Topics: Adult; Anesthetics, Local; Autonomic Nerve Block; Blood Pressure; Dental Pulp; Electric Stimulation; | 2003 |
Potent inhibition of burn pain without use of opiates.
Topics: Adolescent; Analgesia; Analgesics, Opioid; Anesthetics, Local; Bandages; Burns; Humans; Infusions, I | 2003 |
Transdermal delivery of lidocaine in vitro by alternating current.
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Electricity; In Vitro Techniques; Iontophore | 2003 |
Using lidocaine for peripheral i.v. insertions: patients' preferences and pain experiences.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Attitude to Health; Catheterization, | 2003 |
Instrumental learning within the spinal cord: V. Evidence the behavioral deficit observed after noncontingent nociceptive stimulation reflects an intraspinal modification.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Electroshock; Functional Laterality; Injections, Spin | 2003 |
Multiple phases of relief from experimental mechanical allodynia by systemic lidocaine: responses to early and late infusions.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Functional Laterality; Hyperalgesia; Infusions, Intra | 2003 |
Involvement of the anterior pretectal nucleus in the control of persistent pain: a behavioral and c-Fos expression study in the rat.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Disease Models, Animal; Dose-Response Relatio | 2003 |
Urethral meatal dilatation using topical EMLA cream for anaesthesia.
Topics: Ambulatory Surgical Procedures; Anesthetics, Local; Child; Child, Preschool; Dilatation; Humans; Lid | 2003 |
Allodynia after acute intrathecal morphine administration in a patient with neuropathic pain after spinal cord injury.
Topics: Adrenergic alpha-Agonists; Aged; Analgesics, Opioid; Anesthetics, Local; Clonidine; Humans; Injectio | 2003 |
A personal story regarding pain control.
Topics: Administration, Cutaneous; Aged; Anesthetics, Local; Humans; Lidocaine; Male; Pain; Pressure Ulcer; | 2003 |
A reappraisal of local anesthesia for prostate brachytherapy.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Brachytherapy; Humans; Lidocaine; Male; Middle Aged; Pa | 2003 |
Radicular pain after vertebroplasty: compression or irritation of the nerve root? Initial experience with the "cooling system".
Topics: Adult; Aged; Anesthetics, Local; Bone Cements; Humans; Lidocaine; Middle Aged; Orthopedic Procedures | 2003 |
Attenuation of neuropathic manifestations by local block of the activities of the ventrolateral orbito-frontal area in the rat.
Topics: Adrenergic Agents; Anesthetics, Local; Animals; Cold Temperature; Disease Models, Animal; Electricit | 2003 |
A clinical evaluation of xylocaine anesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Lidocaine; Pain; Pain Management; Procaine | 1956 |
A clinical evaluation of xylocaine anesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Lidocaine; Pain; Pain Management; Procaine | 1956 |
A clinical evaluation of xylocaine anesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Lidocaine; Pain; Pain Management; Procaine | 1956 |
A clinical evaluation of xylocaine anesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Lidocaine; Pain; Pain Management; Procaine | 1956 |
[Clinic experience with the local anesthetic, leostesin].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthetics, Local; Lidocaine; Pain; Pain Managemen | 1956 |
[Clinic experience with the local anesthetic, leostesin].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthetics, Local; Lidocaine; Pain; Pain Managemen | 1956 |
[Clinic experience with the local anesthetic, leostesin].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthetics, Local; Lidocaine; Pain; Pain Managemen | 1956 |
[Clinic experience with the local anesthetic, leostesin].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthetics, Local; Lidocaine; Pain; Pain Managemen | 1956 |
[New opportunities of local anesthesia in modern surgery].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Lidocaine; Pain; Pain Management | 1956 |
[New opportunities of local anesthesia in modern surgery].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Lidocaine; Pain; Pain Management | 1956 |
[New opportunities of local anesthesia in modern surgery].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Lidocaine; Pain; Pain Management | 1956 |
[New opportunities of local anesthesia in modern surgery].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Lidocaine; Pain; Pain Management | 1956 |
Intramuscular lignocaine; an adjuvant to nitrous oxide-oxygen anaesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Lidocaine; Nitrous Oxide; Oxygen; Pain; Pai | 1957 |
Epidural block with xylocaine.
Topics: Analgesia; Anesthesia; Humans; Lidocaine; Pain | 1957 |
Infrared analysis for the estimation of carbon dioxide in the presence of nitrous oxide.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesiology; Carbon Dioxide; Humans; Lidocaine; | 1957 |
[A new local anesthetic, diethylamino-2,6-dimethylacetanilid (maricaine) in eye surgery].
Topics: Analgesia; Anesthesia; Anesthesia, Local; Anesthetics, Local; Eye; Humans; Lidocaine; Ophthalmologic | 1957 |
[Intravenous lidocaine in anesthesia].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Lidocaine; Pain; Pain Management | 1957 |
Intravenous lignocaine anaesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Intravenous; Humans; Lidocaine; Pain | 1958 |
[New treatment of painful throat infections].
Topics: Disease; Humans; Lidocaine; Pain; Pharyngeal Diseases; Pharyngitis; Pharynx | 1958 |
Neuromuscular block with lignocaine.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Conduction; Humans; Lidocaine; Neuromus | 1958 |
[Xylocaine anesthesia in cystoscopy].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Cystoscopy; Lidocaine; Pain; Pain Management | 1959 |
The control of postoperative pain by the use of local anesthetic pumps.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Anesthetics, Local; Humans; Lido | 1959 |
[Experience with endovenous use of xylocaine].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Lidocaine; Pain; Pain Management | 1959 |
Xylocaine (lidocaine) viscous. A topical anesthetic agent of value for the relief of pain associated with oral mucous membrane lesions.
Topics: Anesthetics, Local; Eye; Humans; Lidocaine; Mouth; Mouth Diseases; Mucous Membrane; Ophthalmologic S | 1960 |
[Use of lidocaine in anesthesia of the mucosa in urological practice].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Lidocaine; Mucous Membrane; Pain; Urology | 1961 |
An invalidated state followed the shock due to xylocaine-anesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Brain; Brain Diseases; Lidocaine; Pain; Pain Manage | 1959 |
[On anesthesia for the urethra].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Lidocaine; Male; Pain; Pain Management; Ure | 1962 |
Local anesthesia in ophthalmology.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Anesthesiology; Anesthetics, Loc | 1962 |
[Analgetic reducing therapy for pain associated with circulatory insufficiency].
Topics: Baths; Geriatrics; Heparin; Humans; Lidocaine; Pain; Papaverine; Vascular Diseases | 1962 |
Lidocaine (xylocaine) for the relief of postoperative pain.
Topics: Humans; Lidocaine; Pain; Pain, Postoperative; Surgical Procedures, Operative | 1962 |
Alleviation of post tonsillectomy pain and infection. A preliminary report.
Topics: Humans; Lidocaine; Methylprednisolone; Pain; Penicillins; Tonsillectomy | 1963 |
LOCAL ANAESTHETICS FOR CHRONIC PAIN.
Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Autonomic Nerve Block; Chronic Pain; Geriatrics; | 1964 |
[ON ANALGESIA FOLLOWING TONSILLECTOMY WITH A VISCOUS SURFACE ANESTHETIC].
Topics: Analgesia; Anesthetics; Humans; Lidocaine; Pain; Pain Management; Postoperative Care; Tonsillectomy | 1963 |
[EFFECTS OF PHARMACOLOGICAL BLOCKING OF THE STELLATE GANGLION ON CUTANEOUS PAIN SENSITIVITY IN NORMAL INDIVIDIALS].
Topics: Administration, Cutaneous; Autonomic Nerve Block; Electrophysiology; Humans; Lidocaine; Pain; Pain T | 1963 |
[EXPLORATION OF THE SENSORY FUNCTION OF THE UPPER LIMB AND OF THE CORRELATED CUTANEOUS PHENOMENA IN FIBROMYALGIAS. EFFECTS OF BLOCKING OF THE SENSORY PATHWAYS AND STELLATE GANGLION].
Topics: Arm; Autonomic Nerve Block; Electrophysiology; Fibromyalgia; Humans; Lidocaine; Muscular Diseases; P | 1963 |
THE PAINFUL SHOULDER.
Topics: Arthritis; Bursitis; Drug Therapy; Humans; Hydrocortisone; Joints; Lidocaine; Osteoarthritis; Pain; | 1964 |
[EVISCERATION. SUPPRESSION OF POSTOPERATIVE PAIN AND REACTION].
Topics: Anesthesia; Anesthesia, General; Dexamethasone; Eye; Humans; Lidocaine; Pain; Pain, Postoperative; P | 1964 |
TO-DAY'S DRUGS. LOCAL ANALGESICS.
Topics: Analgesia; Analgesics; Dibucaine; Lidocaine; Pain; Pharmacology; Procaine; Tetracaine; Toxicology | 1964 |
MANAGEMENT OF PAIN AND INFECTION OF TONSILLECTOMY.
Topics: Adolescent; Analgesia; Biomedical Research; Humans; Lidocaine; Methylprednisolone; Pain; Pain Manage | 1964 |
THE MANAGEMENT OF PAIN.
Topics: Anesthesia; Anesthesia, Spinal; Anesthetics; Anesthetics, Local; Autonomic Nerve Block; Humans; Lido | 1964 |
THE RELIEF OF PAIN AFTER THORACOTOMY.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Dextrans; Drug Therapy; Epinephrine; Geriatrics; | 1964 |
THE MEASUREMENT OF HUMAN DENTAL INTRAPULPAL PRESSURE AND ITS RESPONSE TO CLINICAL VARIABLES.
Topics: Adolescent; Biomedical Research; Blood Pressure; Blood Pressure Determination; Body Fluids; Capillar | 1965 |
RECENT ADVANCES IN LOCAL ANALGESIA. CLINICAL EXPERIENCE WITH PRILOCAINE.
Topics: Analgesia; Anesthesia; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics; Anesthetics, Lo | 1965 |
SINGLE-INJECTION CAUDAL EPIDURAL ANALGESIA.
Topics: Analgesia, Epidural; Anesthesia; Anesthesia, Spinal; Biomedical Research; Epinephrine; Humans; Lidoc | 1965 |
Anaesthesia with leostesin (lidocaine) and pethidine in bronchoscopy.
Topics: Aged; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesiology; Bronchoscopy; Humans; Lidocai | 1959 |
[Anesthesia with leostesin (lidocaine) and pethidine in bronchoscopy].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Bronchoscopy; Humans; Lidocaine; Meperidine; Pain; | 1959 |
[Use of Xylocaine viscous in tracheo-bronchoscopy].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Bronchoscopy; Lidocaine; Pain; Pain Management | 1962 |
[Mucous membrane anesthesia with a 10 per cent xylocaine liquid spray].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Lidocaine; Mucous Membrane; Pain; Pain Management | 1961 |
Perceptual integration of intramuscular electrical stimulation in the focal and the referred pain area in healthy humans.
Topics: Adult; Anesthetics, Local; Arm; Conditioning, Psychological; Electric Stimulation; Female; Humans; L | 2003 |
The critical role of concentration for lidocaine block of peripheral nerve in vivo: studies of function and drug uptake in the rat.
Topics: Anesthetics, Inhalation; Anesthetics, Local; Animals; Behavior, Animal; Dose-Response Relationship, | 2003 |
Lidocaine patch helpful in managing the chronic pain of leg ulceration.
Topics: Administration, Topical; Anesthetics, Local; Chronic Disease; Female; Humans; Leg Ulcer; Lidocaine; | 2003 |
Plain talk about wound pain.
Topics: Administration, Cutaneous; Algorithms; Anesthetics, Local; Chronic Disease; Decision Trees; Humans; | 2003 |
Do unto others--why I would want anesthesia for my prostate biopsy.
Topics: Analgesia; Anxiety; Biopsy, Needle; Humans; Lidocaine; Male; Nerve Block; Pain; Prostate; Randomized | 2003 |
Bone scan 14 days after a toxic lignocaine reaction.
Topics: Adult; Anaphylaxis; Angioedema; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Inci | 2004 |
Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain.
Topics: Amiodarone; Anesthetics, Local; Animals; Cold Temperature; Hot Temperature; Hyperalgesia; Injections | 2004 |
New treatment for troublesome vulvar pain.
Topics: Anesthetics, Local; Coitus; Female; Humans; Lidocaine; Pain; Vulvar Diseases | 2004 |
A new method of postoperative anorectal analgesia.
Topics: Anal Canal; Analgesia; Humans; Lidocaine; Pain; Rectum | 1951 |
Does lidocaine-prilocaine cream (EMLA) decrease the pain of neonatal circumcision?
Topics: Anesthetics, Combined; Anesthetics, Local; Circumcision, Male; Evidence-Based Medicine; Heart Rate; | 2004 |
Local anaesthetic and steroid combined injection therapy in the management of non-cyclical mastalgia.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Breast Diseases; Female; Huma | 2004 |
Preliminary results of colour Doppler-guided intratendinous glucocorticoid injection for Achilles tendonitis in five patients.
Topics: Achilles Tendon; Adult; Aged; Chronic Disease; Drug Combinations; Drug Therapy, Computer-Assisted; E | 2004 |
Prostate brachytherapy under local anesthesia; lessons from the first 600 patients.
Topics: Anesthesia, Local; Anesthetics, Local; Brachytherapy; Humans; Lidocaine; Male; Pain; Patient Satisfa | 2002 |
Substance P release in the cat spinal cord upon afferent C-fibre stimulation is not attenuated by clonidine at analgesic doses.
Topics: Afferent Pathways; Analgesics; Animals; Cats; Clonidine; Dose-Response Relationship, Drug; Down-Regu | 2004 |
Thalamic modulation of visceral nociceptive processing in adult rats with neonatal colon irritation.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Catheterization; Colitis; Electrophysiology; Lidocain | 2004 |
The long-term effect of repeated intravenous lidocaine on central pain and possible correlation in positron emission tomography measurements.
Topics: Aged; Female; Humans; Infusions, Intravenous; Lidocaine; Pain; Pons; Thalamus; Time; Tomography, Emi | 2004 |
Intralesional treatment in painful rib metastases.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Bone Neoplasms; Humans | 2004 |
Ketamine to reduce propofol injection pain.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Child; Clinical Trials as Topic; Drug Combinations; Dr | 2004 |
Surgical pearl: tumescent anesthesia reduces pain of axillary laser hair removal.
Topics: Anesthesia, Local; Axilla; Hair Removal; Humans; Laser Therapy; Lidocaine; Pain | 2004 |
Sonographically guided injection of anesthetic for iliopsoas tendinopathy after total hip arthroplasty.
Topics: Adult; Anesthetics, Local; Arthroplasty, Replacement, Hip; Betamethasone; Bupivacaine; Female; Groin | 2004 |
Injectable microparticle-gel system for prolonged and localized lidocaine release. II. In vivo anesthetic effects.
Topics: Anesthetics, Local; Animals; Biocompatible Materials; Delayed-Action Preparations; Drug Carriers; Ge | 2004 |
[Therapy of chronic pain with lidocaine plasters].
Topics: Administration, Topical; Humans; Lidocaine; Pain; Syndrome | 2004 |
Antinociception induced by stimulating the anterior pretectal nucleus in two models of pain in rats.
Topics: Analgesia; Anesthetics, Local; Animals; Brain; Disease Models, Animal; Efferent Pathways; Electric S | 2004 |
Painful and non-painful pressure sensations from human skeletal muscle.
Topics: Adult; Afferent Pathways; Anesthetics, Local; Female; Humans; Ischemia; Lidocaine; Male; Mechanorece | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Evaluation of the tail formalin test in mice as a new model to assess local analgesic effects.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; D | 2004 |
Introduction: chronic pain studies of the lidocaine patch 5% using the Neuropathic Pain Scale.
Topics: Administration, Cutaneous; Anesthetics, Local; Chronic Disease; Humans; Lidocaine; Neuralgia; Pain; | 2004 |
Conclusions: chronic pain studies of lidocaine patch 5% using the Neuropathic Pain Scale.
Topics: Administration, Cutaneous; Anesthetics, Local; Chronic Disease; Clinical Trials as Topic; Humans; Li | 2004 |
Intravenous lidocaine relieves severe pain: results of an inpatient hospice chart review.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; California; Drug Utilization; Female; Hospice Ca | 2004 |
Central neuropathic itch from spinal-cord cavernous hemangioma: a human case, a possible animal model, and hypotheses about pathogenesis.
Topics: Anesthetics, Local; Animals; Disease Models, Animal; Hemangioma, Cavernous; Humans; Laminectomy; Lid | 2005 |
Using EMLA cream before venipuncture.
Topics: Adolescent; Anesthetics, Local; Child; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Oi | 2005 |
[2/6 EMLA cream application].
Topics: Administration, Cutaneous; Age Factors; Anesthetics, Combined; Anesthetics, Local; Child; Child, Pre | 2004 |
Patching up your pain. The transition from pill to patch has spawned products for both chronic and short-term ailments.
Topics: Administration, Cutaneous; Analgesics; Fentanyl; Humans; Lidocaine; Nonprescription Drugs; Pain | 2004 |
Pain induced by phacoemulsification without sedation using topical or peribulbar anesthesia.
Topics: Adult; Aged; Aged, 80 and over; Aminobenzoates; Anesthesia, Local; Anesthetics, Combined; Anesthetic | 2005 |
Pain therapy in horses.
Topics: Analgesia; Anesthetics, Local; Animals; Horse Diseases; Horses; Lidocaine; Nociceptors; Pain; Specie | 2005 |
Effect of systemic lidocaine on visceral and somatic nociception in conscious horses.
Topics: Analgesia; Anesthetics, Local; Animals; Colon; Female; Horse Diseases; Horses; Infusions, Intravenou | 2005 |
Emergency physicians' practices and attitudes regarding procedural anaesthesia for nasogastric tube insertion.
Topics: Administration, Topical; Anesthesia; Anesthetics; Attitude of Health Personnel; Clinical Competence; | 2005 |
Fatal case of BOTOX-related anaphylaxis?
Topics: Adult; Anaphylaxis; Anesthetics, Local; Botulinum Toxins, Type A; Fatal Outcome; Female; Humans; Lid | 2005 |
Vascular access.
Topics: Anesthetics, Combined; Anesthetics, Local; Arteriovenous Shunt, Surgical; Hemodialysis, Home; Humans | 2005 |
The prevention of pain from injection of propofol by dexmedetomidine and comparison with lidocaine.
Topics: Dexmedetomidine; Humans; Injections, Intravenous; Lidocaine; Pain; Propofol | 2005 |
Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Blood Pressure; Cats | 2005 |
Bupivacaine versus lidocaine analgesia for neonatal circumcision.
Topics: Acetaminophen; Administration, Topical; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; C | 2005 |
Propofol-induced injection pain: comparison of a modified propofol emulsion and standard propofol with premixed lidocaine.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Drug Combinations; Emulsions; | 2005 |
The pain of venous cannulation.
Topics: Anesthetics, Local; Catheterization, Peripheral; Humans; Lidocaine; Pain | 2005 |
Do no harm--but first, do not hurt.
Topics: Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Child; Humans; Infant; Lidocaine | 2005 |
Comparison of propofol with lidocaine pretreatment versus propofol formulated with long- and medium-chain triglycerides or confounding effect of tourniquet.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Chemistry, Pharmaceutical; Excipients; Humans; Injecti | 2005 |
Local anaesthetics attenuates spinal nociception and HPA-axis activation during experimental laparotomy in pigs.
Topics: Adrenocorticotropic Hormone; Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; C-Reactive | 2005 |
Intra-operative pain perception in tooth extraction--possible causes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Dental; Anesthetics, Local; Dental Anxiety; | 2005 |
High doses of topically applied lidocaine in a cancer patient.
Topics: Administration, Topical; Anesthetics, Local; Bone Neoplasms; Humans; Lidocaine; Osteosarcoma; Pain; | 2005 |
Topical lidocaine helps reduce pain of digital ulcers in systemic sclerosis (scleroderma).
Topics: Administration, Oral; Administration, Topical; Anesthetics, Local; Anti-Infective Agents; Ciprofloxa | 2006 |
Topical lidocaine helps reduce pain of digital ulcers in systemic sclerosis (scleroderma).
Topics: Administration, Oral; Administration, Topical; Anesthetics, Local; Anti-Infective Agents; Ciprofloxa | 2006 |
Topical lidocaine helps reduce pain of digital ulcers in systemic sclerosis (scleroderma).
Topics: Administration, Oral; Administration, Topical; Anesthetics, Local; Anti-Infective Agents; Ciprofloxa | 2006 |
Topical lidocaine helps reduce pain of digital ulcers in systemic sclerosis (scleroderma).
Topics: Administration, Oral; Administration, Topical; Anesthetics, Local; Anti-Infective Agents; Ciprofloxa | 2006 |
Lidocaine patch for pain of erythromelalgia: follow-up of 34 patients.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Erythromelalgia; Female; Follow-Up Studies; Humans; Lid | 2005 |
Successful treatment of persistent vulvodynia with submucous infiltration of betamethasone and lidocaine.
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Betamethasone; Female; Humans; Injections, Subc | 2006 |
Lateral plantar nerve injury following steroid injection for plantar fasciitis.
Topics: Adult; Anesthetics, Local; Fasciitis, Plantar; Foot; Heel; Humans; Hypesthesia; Injections; Lidocain | 2005 |
Pain management with interventional spine therapy in patients with spinal cord injury: a case series.
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Autonomic Dysreflexia; Chronic Disease; Disease | 2005 |
[Tolerability and complications of the ultrasound guided transrectal biopsy of the prostate extended to 10 cores. The role of neurovascular bundle blockage with lidocaine].
Topics: Anesthetics, Local; Biopsy; Humans; Lidocaine; Male; Nerve Block; Pain; Postoperative Complications; | 2005 |
Effect of application duration of 2% lidocaine jelly on aqueous lidocaine concentration for topical anesthesia in cataract surgery.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Aqueous Humor; Chromatography | 2006 |
Pain induced by phacoemulsification without sedation using topical or peribulbar anesthesia.
Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Conscious Sedation; Human | 2006 |
The lidocaine patch: a useful addition to the pain clinic armamentarium.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Chronic Disease; Female; Humans; Lidocaine; Ne | 2006 |
Anesthetic management of a labouring parturient with urticaria pigmentosa.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Intravenous; | 2006 |
Hypoechoic space formation with periprostatic nerve block: myth or reality?
Topics: Aged; Anesthetics, Local; Biopsy, Needle; Humans; Injections; Lidocaine; Male; Middle Aged; Nerve Bl | 2006 |
Plain talk about wound pain.
Topics: Acute Disease; Anesthetics, Local; Attitude to Health; Chronic Disease; Humans; Lidocaine; Nursing A | 2005 |
Pain- and distress-reducing interventions for venepuncture in children.
Topics: Anesthetics; Anesthetics, Combined; Anesthetics, Local; Child; Child Behavior; Child, Preschool; Fem | 2006 |
Palmar hyperhidrosis. Safety efficacy of two anaesthetic techniques for botulinum toxin therapy.
Topics: Anesthesia, Local; Anesthetics, Local; Autonomic Nerve Block; Botulinum Toxins, Type A; Hand; Humans | 2006 |
Perianal and intrarectal anaesthesia for transrectal biopsy of the prostate: a prospective randomized study comparing lidocaine-prilocaine cream and placebo.
Topics: Anesthetics, Combined; Biopsy, Needle; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Ma | 2006 |
Retrobulbar alcohol injection for orbital pain relief under difficult circumstances: a case report.
Topics: Analgesia; Anti-Infective Agents, Local; Carcinoma, Adenoid Cystic; Chronic Disease; Ethanol; Humans | 2006 |
Fascia-iliaca compartment block for femoral bone fracture in prehospital medicine in a 6-yr-old child.
Topics: Anesthetics, Local; Child; Emergency Medical Services; Epinephrine; Female; Femoral Fractures; Human | 2006 |
[Painful defecation and chronic functional constipation in children: Diagnosis and treatment].
Topics: Anal Canal; Anesthetics, Local; Child; Child, Preschool; Chronic Disease; Constipation; Defecation; | 2006 |
Analgesia in the second stage of labour.
Topics: Aerosols; Analgesia, Obstetrical; Anesthetics, Local; Female; Humans; Labor Stage, Second; Lidocaine | 2006 |
Response of central pain syndromes to intravenous lidocaine.
Topics: Adult; Aged; Central Nervous System Diseases; Female; Humans; Injections, Intravenous; Lidocaine; Ma | 1992 |
Predictors of topical anesthetic effectiveness in children.
Topics: Administration, Topical; Age Factors; Anesthetics, Local; Anxiety; Catheterization, Peripheral; Chil | 2007 |
Increased joint loads during walking--a consequence of pain relief in knee osteoarthritis.
Topics: Aged; Anesthetics, Local; Case-Control Studies; Gait; Humans; Injections, Intra-Articular; Knee Join | 2006 |
The need for pain control during scaling and root planing.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Dental Scaling; Humans; Lidocain | 2005 |
Efficacy of an intrapocket anesthetic for scaling and root planing procedures: a review of three multicenter studies.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Clinical Trials as Topic; Dental | 2005 |
Lidocaine patch for the management of leg ulcer pain.
Topics: Administration, Cutaneous; Adult; Aged; Anesthetics, Local; Female; Humans; Leg Ulcer; Lidocaine; Ma | 2006 |
Lidocaine patch for the management of leg ulcer pain.
Topics: Administration, Cutaneous; Adult; Aged; Anesthetics, Local; Female; Humans; Leg Ulcer; Lidocaine; Ma | 2006 |
Lidocaine patch for the management of leg ulcer pain.
Topics: Administration, Cutaneous; Adult; Aged; Anesthetics, Local; Female; Humans; Leg Ulcer; Lidocaine; Ma | 2006 |
Lidocaine patch for the management of leg ulcer pain.
Topics: Administration, Cutaneous; Adult; Aged; Anesthetics, Local; Female; Humans; Leg Ulcer; Lidocaine; Ma | 2006 |
Modulation of neuronal activity in CNS pain pathways following propofol administration in rats: Fos and EEG analysis.
Topics: Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Animals; Central Nervous System; Conscious | 2007 |
Comparison of intraoperative pain responses following intratesticular or mesorchial injection of lidocaine in standing horses undergoing laparoscopic cryptorchidectomy.
Topics: Analgesics; Anesthetics, Local; Animals; Cryptorchidism; Horse Diseases; Horses; Hydrocortisone; Imi | 2006 |
Sudden deflation of a tourniquet caused by lowering of the operating table.
Topics: Blood Loss, Surgical; Equipment Design; Equipment Failure; Fentanyl; Hand; Humans; Intraoperative Co | 2007 |
Liver biopsy: is the pain for real or is it only the fear of it?
Topics: Adult; Aged; Anesthetics, Local; Anxiety; Biopsy, Needle; Fear; Female; Health Knowledge, Attitudes, | 2007 |
[Use of ways to prevent pain].
Topics: Age Factors; Analgesia; Anesthetics, Local; Attitude of Health Personnel; Benchmarking; Blood Specim | 2006 |
Reducing noise and pain during TNP therapy for pilonidal disease.
Topics: Chlorhexidine; Drug Combinations; Emollients; Humans; Lidocaine; Noise; Pain; Petrolatum; Pilonidal | 2007 |
[Italian guidelines and recommendations for prevention and treatment of pain in the newborn].
Topics: Adjuvants, Anesthesia; Analgesics; Analgesics, Opioid; Anesthetics, Local; Atropine; Drug Therapy, C | 2006 |
Reorganization of dorsal root ganglion neurons following chronic sciatic nerve constriction injury: correlation with morphine and lidocaine analgesia.
Topics: Analgesia; Analgesics, Opioid; Anesthetics, Local; Animals; Constriction; Drug Therapy, Combination; | 2007 |
Topical lidocaine in silver sulfadiazine cream on painful, cancer, or treatment-related skin lesions.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Drug Combinations; Female; Humans; Lidocai | 2007 |
Role of 4-aminopyridine-sensitive potassium channels in peripheral antinociception.
Topics: 4-Aminopyridine; Anesthetics, Local; Animals; Female; Lidocaine; Pain; Potassium Channel Blockers; P | 2007 |
Ketamine versus lidocaine for the pain of propofol injection.
Topics: Humans; Injections, Intravenous; Ketamine; Lidocaine; Pain; Propofol | 2007 |
Reducing the pain during children's immunizations.
Topics: Anesthetics, Local; Child; Child, Preschool; Glucose; Humans; Infant; Lidocaine; Lidocaine, Prilocai | 2007 |
The quaternary lidocaine derivative, QX-314, produces long-lasting local anesthesia in animal models in vivo.
Topics: Action Potentials; Anesthesia, Local; Anesthetics, Local; Animals; Disease Models, Animal; Dose-Resp | 2007 |
Ultra-low dose combined spinal-epidural anaesthesia.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Combined; Ane | 2007 |
Factors influencing pain during transrectal ultrasonography-guided prostate biopsy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesia; Anesthetics, Local; Anti-Inflammato | 2008 |
Itch induced by a novel method leads to limbic deactivations a functional MRI study.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Brain; Codeine; Data Interpretation, Statistical; Fem | 2007 |
Retrobulbar hemorrhage after sub-Tenon's anesthesia.
Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Connective Tissue; Diabet | 2007 |
Local anesthesia: an appropriate technology for simple fistula repair.
Topics: Adolescent; Adult; Anesthesia, Local; Female; Gynecologic Surgical Procedures; Humans; Lidocaine; Mi | 2007 |
Routine immunization practices: use of topical anesthetics and oral analgesics.
Topics: Acetaminophen; Administration, Oral; Administration, Topical; Adult; Analgesics, Non-Narcotic; Anest | 2007 |
Routine immunization practices: use of topical anesthetics and oral analgesics.
Topics: Acetaminophen; Administration, Oral; Administration, Topical; Adult; Analgesics, Non-Narcotic; Anest | 2007 |
Routine immunization practices: use of topical anesthetics and oral analgesics.
Topics: Acetaminophen; Administration, Oral; Administration, Topical; Adult; Analgesics, Non-Narcotic; Anest | 2007 |
Routine immunization practices: use of topical anesthetics and oral analgesics.
Topics: Acetaminophen; Administration, Oral; Administration, Topical; Adult; Analgesics, Non-Narcotic; Anest | 2007 |
Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesia.
Topics: Adolescent; Adult; Aged; Aging; Analysis of Variance; Anesthetics, Local; Chronic Disease; Cohort St | 2007 |
Meperidine prolongs lidocaine caudal epidural anaesthesia in the horse.
Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Animals; Drug Synergism; Female; Horses; Lidocaine; Mal | 2008 |
Editorial comment on: topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial.
Topics: Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Nerve Block; Oin | 2008 |
Editorial comment on: topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial.
Topics: Anesthetics, Combined; Anesthetics, Local; Biopsy, Needle; Humans; Lidocaine; Male; Nerve Block; Oin | 2008 |
Local anesthetic treatment significantly attenuates acute pain responding but does not prevent the neonatal injury-induced reduction in adult spinal behavioral plasticity.
Topics: Acute Disease; Anesthetics, Local; Animals; Animals, Newborn; Behavior, Animal; Electroshock; Inject | 2007 |
Neuroscience: a local route to pain relief.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Capsaicin; Cell Membrane Permeability; Electric Cond | 2007 |
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Capsaicin; Cell Membrane Permeability; Electric Cond | 2007 |
Pelvic nerve input mediates descending modulation of homovisceral processing in the thoracolumbar spinal cord of the rat.
Topics: Anesthetics, Local; Animals; Colon; Electrophysiology; Female; Hypogastric Plexus; Lidocaine; Lumbos | 2007 |
Chillies: out of the frying pan and into the clinic?
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Capsaicin; Drug Interactions; Humans; Lidocai | 2007 |
Inactivation of the periaqueductal gray attenuates antinociception elicited by stimulation of the rat medial preoptic area.
Topics: Analgesia; Anesthetics, Local; Animals; Homocysteine; Hyperalgesia; Lidocaine; Male; Microinjections | 2007 |
Control of pain during transrectal ultrasound-guided prostate biopsy: a prospective study comparing two methods.
Topics: Aged; Biopsy, Needle; Case-Control Studies; Diclofenac; Humans; Injections, Intramuscular; Lidocaine | 2007 |
[The efficacy of local anaesthetics administered prior to castration of male suckling piglets].
Topics: Anesthetics, Local; Animals; Aspartate Aminotransferases; Creatine Kinase; Hydrocortisone; Lidocaine | 2007 |
The efficacy and neurotoxicity of dexmedetomidine administered via the epidural route.
Topics: Adrenergic alpha-Agonists; Anesthesia, Epidural; Anesthetics, Local; Animals; Blood Gas Analysis; Bl | 2008 |
The efficacy and neurotoxicity of dexmedetomidine administered via the epidural route.
Topics: Adrenergic alpha-Agonists; Anesthesia, Epidural; Anesthetics, Local; Animals; Blood Gas Analysis; Bl | 2008 |
The efficacy and neurotoxicity of dexmedetomidine administered via the epidural route.
Topics: Adrenergic alpha-Agonists; Anesthesia, Epidural; Anesthetics, Local; Animals; Blood Gas Analysis; Bl | 2008 |
The efficacy and neurotoxicity of dexmedetomidine administered via the epidural route.
Topics: Adrenergic alpha-Agonists; Anesthesia, Epidural; Anesthetics, Local; Animals; Blood Gas Analysis; Bl | 2008 |
Patient comfort in regional anesthesia.
Topics: Administration, Topical; Anesthetics, Local; Drug Combinations; Humans; Lidocaine; Nerve Block; Oint | 2008 |
Listen to the data when results are not significant.
Topics: Abortifacient Agents, Nonsteroidal; Administration, Inhalation; Administration, Oral; Adolescent; An | 2008 |
A new way to reduce common but painful medical procedures.
Topics: Anesthetics, Local; Child; Humans; Lidocaine; Pain; Punctures | 2007 |
Prevention of retrobulbar hemorrhage after sub-Tenon anesthesia.
Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Connective Tissue; Diabet | 2008 |
Modified Bier block anesthetic technique is safe for office use for botulinum a toxin treatment of palmar and plantar hyperhidrosis.
Topics: Anesthesia, Local; Anesthetics, Local; Botulinum Toxins, Type A; Hand; Humans; Hyperhidrosis; Inject | 2007 |
Improving pain management for pediatric patients undergoing nonurgent painful procedures.
Topics: Administration, Topical; Adolescent; Analgesics; Anesthetics, Local; Child; Child, Preschool; Humans | 2008 |
Challenges in cancer pain management--bone pain.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Bone Diseases | 2008 |
What is the mechanism underlying treatment of pain by systemic application of lidocaine?
Topics: Animals; Humans; Infusions, Intravenous; Lidocaine; Nerve Fibers, Unmyelinated; Pain; Treatment Outc | 2008 |
Reversal of visceral and somatic hypersensitivity in a subset of hypersensitive rats by intracolonic lidocaine.
Topics: Abdominal Pain; Animals; Colon; Lidocaine; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; | 2008 |
Effects of intrathecal lidocaine on hyperalgesia and allodynia following chronic constriction injury in rats.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Chronic Disease; Constriction, Pathologic; Hot Temper | 2009 |
Topical anesthesia with EMLA does not decrease pain during vasectomy.
Topics: Adult; Anesthetics, Local; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Pain; Pr | 2008 |
Extradural analgesia for pain relief.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Pre | 1967 |
Non-operative management of coccygodynia.
Topics: Humans; Lidocaine; Methods; Pain; Sacrococcygeal Region; Triamcinolone | 1980 |
Painless neonatal circumcision.
Topics: Anesthesia, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Male; Nerve Block; Pain; | 1980 |
Complete heart block after sublingual nitroglycerin.
Topics: Administration, Oral; Electrocardiography; Heart Block; Humans; Hypotension; Lidocaine; Male; Middle | 1983 |
Treatment of painful conditions of the abdominal wall with local injections.
Topics: Abdominal Muscles; Adolescent; Adult; Drug Combinations; Female; Humans; Injections, Intramuscular; | 1980 |
Obturator neuropathy after forceps delivery.
Topics: Adult; Carbamazepine; Delivery, Obstetric; Female; Humans; Hyperesthesia; Lidocaine; Methylprednisol | 1984 |
[Combined use of droperidol and xylocitin in peripheral arteriography].
Topics: Acetrizoic Acid; Angiography; Arterial Occlusive Diseases; Contrast Media; Droperidol; Drug Therapy, | 1984 |
[Are local pain elimination procedures for emergency patients at the emergency site and during transportation really contraindicated?].
Topics: Anesthesia, Local; Emergencies; First Aid; Fractures, Bone; Humans; Lidocaine; Pain; Transportation | 1984 |
Do large diameter cutaneous afferents have a role in the transmission of nociceptive messages?
Topics: Acoustic Stimulation; Adult; Afferent Pathways; Female; Humans; Lidocaine; Male; Neurons; Nociceptor | 1984 |
Sensitivity to pain predicts CNS sensitivity to lidocaine.
Topics: Brain; Double-Blind Method; Humans; Infusions, Parenteral; Injections, Intravenous; Lidocaine; Male; | 1984 |
Please pass me the onions and the socks--lidocaine toxicity.
Topics: Herpangina; Humans; Infant; Lidocaine; Mouth Diseases; Pain; Stomatitis, Herpetic | 1983 |
Intraligamentary anesthesia: a double-blind comparative study.
Topics: Adult; Anesthesia, Dental; Bupivacaine; Dental Pulp Test; Double-Blind Method; Epinephrine; Evaluati | 1984 |
Minimizing the pain of local anesthesia.
Topics: Adult; Anesthesia, Local; Body Temperature; Humans; Injections, Subcutaneous; Lidocaine; Pain; Proba | 1983 |
The efficacy of xylocaine topical anaesthetic in reducing injection pain.
Topics: Administration, Topical; Adult; Anesthesia, Dental; Anesthesia, Local; Humans; Injections; Lidocaine | 1983 |
Anesthesia in chalazion surgery.
Topics: Anesthesia, Local; Eyelid Diseases; Humans; Lidocaine; Pain | 1983 |
Diagnostic maneuvers in painful syndromes.
Topics: Barbiturates; Humans; Lidocaine; Nerve Block; Pain; Spinal Cord | 1983 |
A radiopaque-labeling technique to visualize the distribution of local anesthesia.
Topics: Anesthesia, Local; Arthritis; Diatrizoate; Drug Combinations; Female; Humans; Lidocaine; Middle Aged | 1983 |
The use of lignocaine and hydrocortisone in the diagnosis and management of chest wall pain masquerading as ischaemic cardiac pain.
Topics: Coronary Disease; Diagnosis, Differential; Humans; Hydrocortisone; Lidocaine; Pain; Thorax | 1983 |
Relative contributions of the nucleus raphe magnus and adjacent medullary reticular formation to the inhibition by stimulation in the periaqueductal gray of a spinal nociceptive reflex in the pentobarbital-anesthetized rat.
Topics: Animals; Brain Mapping; Brain Stem; Electric Stimulation; Lidocaine; Male; Nerve Block; Neural Inhib | 1984 |
[Efficacy of intra-arterial lidocaine in the control of pain in arteriography of the arm and leg (author's transl)].
Topics: Angiography; Blood Pressure; Contrast Media; Humans; Injections, Intra-Arterial; Lidocaine; Pain | 1980 |
Morbidity from shoulder arthrography: etiology, incidence, and prevention.
Topics: Anesthesia, Local; Contrast Media; Humans; Lidocaine; Methods; Pain; Prospective Studies; Radiograph | 1981 |
[The immediate treatment of acute myocardial infarct].
Topics: Acute Disease; Arrhythmias, Cardiac; First Aid; Furosemide; Hemodynamics; Humans; Isosorbide Dinitra | 1981 |
Spread of epidural analgesia in early pregnancy.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Cold Temperature; Dose-Response Relationship, | 1983 |
Pain relief in herpes zoster.
Topics: Adolescent; Adult; Aged; Analgesics; Bupivacaine; Drug Combinations; Female; Herpes Zoster; Humans; | 1983 |
[Local therapy using a venous cannule, an effective way for pain relief in ununited fractures].
Topics: Aged; Arm Injuries; Fractures, Ununited; Humans; Lidocaine; Male; Pain | 1983 |
More on neck pain.
Topics: Carotid Artery Diseases; Diagnosis, Differential; Humans; Lidocaine; Muscular Diseases; Neck; Pain | 1983 |
Using local anesthesia to ease venipuncture.
Topics: Anesthesia, Local; Bloodletting; Humans; Lidocaine; Pain | 1981 |
Local anesthesia for Herpes Zoster.
Topics: Anesthesia, Local; Herpes Zoster; Humans; Lidocaine; Neuralgia; Pain | 1980 |
Elimination of pain caused by Small-Carrion penile prosthesis.
Topics: Anesthesia, Local; Humans; Lidocaine; Male; Middle Aged; Pain; Pain Management; Penis; Prostheses an | 1982 |
Elimination of pain caused by Small-Carrion prosthesis.
Topics: Humans; Lidocaine; Male; Pain; Penis; Prostheses and Implants | 1982 |
The influence of lidocaine and iontophoresis on the pain threshold of the human eardrum.
Topics: Adult; Epinephrine; Humans; Iontophoresis; Lidocaine; Pain; Sensory Thresholds; Tympanic Membrane | 1982 |
Analgesic responses to i.v. lignocaine.
Topics: Adult; Aged; Humans; Ischemia; Lidocaine; Middle Aged; Pain; Pain, Intractable | 1982 |
Pain reduction with etomidate injection.
Topics: Adult; Anesthesia, Intravenous; Etomidate; Female; Humans; Imidazoles; Lidocaine; Pain | 1982 |
Does lidocaine-prilocaine cream permit painfree insertion of IV catheters in children?
Topics: Adolescent; Catheterization; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Emulsions; | 1982 |
Gnawing is the preferred consummatory behavior initially induced by tail pinch.
Topics: Animals; Feeding Behavior; Food Preferences; Lidocaine; Male; Mastication; Nerve Block; Pain; Rats; | 1982 |
[Intra-arterial lidocaine in arteriography of lower extremities. Analgesic action and side-effects].
Topics: Analgesics; Angiography; Contrast Media; Humans; Injections, Intra-Arterial; Leg; Lidocaine; Pain | 1982 |
Effects of local anesthetic infiltration on brain potentials evoked by painful dental stimulation.
Topics: Anesthetics, Local; Brain; Dental Pulp; Electric Stimulation; Evoked Potentials, Somatosensory; Fema | 1981 |
Low temperature painful stimulus alters brain wave pattern of transcutaneous electrical stimulus.
Topics: Animals; Cold Temperature; Electric Stimulation; Electroencephalography; Evoked Potentials; Humans; | 1981 |
[Reduction of side effects in aortofemoral angiography: low-osmolar contrast medium compared with conventional contrast medium plus local anaesthetic (author's transl)].
Topics: Aged; Aortography; Blood Pressure; Double-Blind Method; Female; Femoral Artery; Heart Rate; Hot Temp | 1981 |
Comparison of 0.25% Marcaine with 0.50% Xylocaine as local anesthetic agents (both with 1:200,000 epinephrine)
Topics: Bupivacaine; Ecchymosis; Epinephrine; Humans; Injections; Lidocaine; Pain | 1980 |
[Local anesthetics and antalgic therapy].
Topics: Anesthetics, Local; Bupivacaine; Humans; Lidocaine; Mepivacaine; Nerve Block; Pain | 1980 |
Myofascial pain syndrome in the foot.
Topics: Aged; Female; Foot Diseases; Humans; Lidocaine; Middle Aged; Muscles; Pain; Syndrome | 1980 |
Metatarsalgia: diagnosis and treatment.
Topics: Child; Female; Foot; Foot Diseases; Gait; Humans; Lidocaine; Male; Metatarsophalangeal Joint; Metata | 1980 |
Persistent cardiovascular and behavioral nociceptive responses to subcutaneous formalin require peripheral nerve input.
Topics: Anesthesia; Anesthetics, Local; Animals; Behavior, Animal; Blood Pressure; Dose-Response Relationshi | 1995 |
Hyperbaric lidocaine spinal anesthesia: do we need an alternative?
Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Drug Monitoring; Humans; Lidocaine; Pain; Perip | 1995 |
[Treatment of chronic cancer pain. Contribution of acupuncture, auriculotherapy and mesotherapy].
Topics: Acupuncture Therapy; Humans; Lidocaine; Neoplasms; Pain; Pain Management; Palliative Care; Reflexoth | 1993 |
Referred ocular pain relieved by suboccipital injection.
Topics: Adult; Aged; Aged, 80 and over; Eye; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Midd | 1995 |
A multifactorial analysis to explain inadequate surgical analgesia after extradural block.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, | 1995 |
Leg pains after spinal anaesthesia.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Female; Humans; Leg; Lidocaine; Pain | 1995 |
Protracted relief of experimental neuropathic pain by systemic local anesthetics. How, where, and when.
Topics: Anesthetics, Local; Animals; Lidocaine; Pain; Peripheral Nervous System Diseases; Rats | 1995 |
Prolonged alleviation of tactile allodynia by intravenous lidocaine in neuropathic rats.
Topics: Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Injections, Intravenous; Lidocaine; M | 1995 |
[Changes in analgesic levels, plasma concentrations and epidurogram during long-term continuous epidural block].
Topics: Adult; Analgesia, Epidural; Bupivacaine; Epidural Space; Female; Fractures, Bone; Humans; Lidocaine; | 1995 |
A study of early ongoing activity in dorsal horn units following sciatic nerve constriction.
Topics: Animals; Electrophysiology; Lidocaine; Ligation; Male; Neurons; Pain; Physical Stimulation; Rats; Ra | 1994 |
Pain during injection of propofol.
Topics: Humans; Injections, Intravenous; Lidocaine; Pain; Propofol; Thiopental | 1995 |
Neurologic evaluation of the rat during sciatic nerve block with lidocaine.
Topics: Animals; Behavior, Animal; Body Weight; Evaluation Studies as Topic; Gait; Heating; Hindlimb; Lidoca | 1995 |
Antinociception produced by an ascending spino-supraspinal pathway.
Topics: Analgesics; Animals; Brain Stem; Cerebral Ventricles; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephali | 1995 |
Bilateral leg pain following lidocaine spinal anaesthesia.
Topics: Achilles Tendon; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Spinal; Back Pain; Cystosc | 1995 |
Hematoma block for ankle fractures: a safe and efficacious technique for manipulations.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Ankle Injuries; Child; Female; | 1995 |
Hematoma block for ankle fractures: a safe and efficacious technique for manipulations.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Ankle Injuries; Child; Female; | 1995 |
Hematoma block for ankle fractures: a safe and efficacious technique for manipulations.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Ankle Injuries; Child; Female; | 1995 |
Hematoma block for ankle fractures: a safe and efficacious technique for manipulations.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Ankle Injuries; Child; Female; | 1995 |
Subanesthetic concentrations of lidocaine selectively inhibit a nociceptive response in the isolated rat spinal cord.
Topics: Animals; Butylamines; Female; In Vitro Techniques; Lidocaine; Male; Naloxone; Pain; Rats; Rats, Spra | 1995 |
Local anaesthesia for cannulation. Has practice changed?
Topics: Anesthesia Department, Hospital; Anesthesia, Local; Attitude of Health Personnel; Catheterization, P | 1995 |
Painless epidural haematoma.
Topics: Aged; Aged, 80 and over; Anesthesia, Epidural; Bupivacaine; Fatal Outcome; Female; Hematoma, Epidura | 1994 |
Buffering lidocaine with sodium bicarbonate.
Topics: Buffers; Humans; Lidocaine; Pain; Pain Measurement; Sodium Bicarbonate | 1994 |
[Pain associated with the injection of Diprivan].
Topics: Adolescent; Adult; Child; Drug Combinations; Humans; Injections, Intravenous; Lidocaine; Pain; Propo | 1994 |
Eutectic mixture of local anesthetic cream--topical anesthesia for extracorporeal shock wave lithotripsy.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Drug Combinations; Humans; Lidocaine; Lidocain | 1994 |
Use of local anaesthetics in guanethidine-induced regional sympathetic blockade.
Topics: Anesthesia, Local; Animals; Autonomic Nerve Block; Drug Therapy, Combination; Guanethidine; Humans; | 1995 |
Further applications for EMLA cream.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anesthetics, Local; Drug Combinations; Humans; Injections | 1994 |
Inguinal herniorrhaphy under local anesthesia: a study of intraoperative tolerance.
Topics: Adipose Tissue; Ambulatory Surgical Procedures; Anesthesia, Local; Female; Hematoma; Hernia, Inguina | 1994 |
EMLA cream in the treatment of causalgic pain.
Topics: Administration, Topical; Adult; Causalgia; Drug Combinations; Humans; Lidocaine; Male; Pain; Priloca | 1994 |
Study of the sensitivity of the diabetes-induced pain model in rats to a range of analgesics.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Aspirin; Clonidine; Diabetes Mellitus, Experi | 1994 |
Management of childhood pain: new approaches to procedure-related pain. Proceedings of a roundtable discussion. Palm Beach, Florida, January 9, 1993.
Topics: Anesthetics, Local; Child; Child, Preschool; Drug Combinations; Humans; Infant; Lidocaine; Lidocaine | 1993 |
Local anesthesia in blepharoplasty: a new look?
Topics: Adult; Aged; Anesthesia, Local; Blepharoptosis; Buffers; Female; Humans; Lidocaine; Male; Middle Age | 1994 |
Reduction of pain and EMG activity in the masseter region by trapezius trigger point injection.
Topics: Adolescent; Adult; Electromyography; Female; Humans; Injections, Intramuscular; Lidocaine; Masseter | 1993 |
Epidural analgesia in the management of severe vaso-occlusive sickle cell crisis.
Topics: Analgesia, Epidural; Anemia, Sickle Cell; Child; Emergencies; Female; Fentanyl; Humans; Lidocaine; M | 1994 |
Multiple bladder biopsies under intravesical lignocaine anaesthesia.
Topics: Aged; Aged, 80 and over; Biopsy, Needle; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Patient | 1994 |
Extirpation and fulguration of multiple superficial bladder tumour recurrences under intravesical lignocaine anaesthesia.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anti-Bacterial Agen | 1994 |
The use of EMLA cream to reduce and/or eliminate procedural pain in children.
Topics: Anesthetics, Local; Child; Drug Combinations; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combinat | 1993 |
A two-year review of pain control during laser therapy using the flashlamp pulsed dye laser.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Local; Anesthetics, Local; Child; Child, P | 1994 |
The rostroventromedial medulla is not involved in alpha 2-adrenoceptor-mediated antinociception in the rat.
Topics: Analysis of Variance; Animals; Cerebellum; Clonidine; Dose-Response Relationship, Drug; Hot Temperat | 1993 |
Response to intravenous lidocaine infusion differs based on clinical diagnosis and site of nervous system injury.
Topics: Central Nervous System; Humans; Infusions, Intravenous; Lidocaine; Pain; Peripheral Nervous System; | 1993 |
Treatment of the cutaneous pain of acute herpes zoster with 9% lidocaine (base) in petrolatum/paraffin ointment.
Topics: Acute Disease; Administration, Cutaneous; Adult; Drug Evaluation; Female; Herpes Zoster; Humans; Lid | 1994 |
Caudal epidural blocks for elderly patients with lumbar canal stenosis.
Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Anti-Inflammatory Agents; Female; Follow-Up Studies; H | 1994 |
Preoperative needle localization in the breast: utility of local anesthesia.
Topics: Anesthesia, Local; Biopsy, Needle; Breast; Female; Humans; Injections, Subcutaneous; Lidocaine; Mens | 1993 |
Acquired methemoglobinemia from multiple oxidants.
Topics: Administration, Topical; Adult; Analgesia, Epidural; Blood Gas Analysis; Bupivacaine; Cytochrome-B(5 | 1993 |
Neuropathic pain in a cancer patient responding to subcutaneously administered lignocaine.
Topics: Adult; Analgesia, Epidural; Autonomic Nerve Block; Evoked Potentials; Hodgkin Disease; Humans; Injec | 1993 |
Effects of the somatostatin analogue octreotide on rectal afferent nerves in humans.
Topics: Administration, Topical; Adult; Afferent Pathways; Catheterization; Compliance; Consciousness; Human | 1993 |
The efficacy and acceptability of using a jet injector in performing digital blocks.
Topics: Adult; Female; Finger Injuries; Humans; Injections, Jet; Lidocaine; Male; Needles; Nerve Block; Pain | 1993 |
Taking the jab out of needles.
Topics: Bloodletting; Drug Combinations; Humans; Injections; Lidocaine; Pain; Prilocaine | 1993 |
Alkalinization of local anesthesia with sodium bicarbonate--preferred method of local anesthesia.
Topics: Anesthesia, Local; Drug Therapy, Combination; Humans; Hydrogen-Ion Concentration; Lidocaine; Male; P | 1994 |
The effect of pre- versus postinjury infiltration with lidocaine on thermal and mechanical hyperalgesia after heat injury to the skin.
Topics: Adult; Burns; Humans; Injections, Subcutaneous; Lidocaine; Male; Pain; Pain Measurement; Physical St | 1993 |
Lidocaine fan.
Topics: Extravasation of Diagnostic and Therapeutic Materials; Humans; Infusions, Intravenous; Lidocaine; Pa | 1993 |
Ischiogluteal bursitis in cancer patients: an infrequently recognized cause of pain.
Topics: Adrenal Cortex Hormones; Adult; Aged; Bursitis; Buttocks; Female; Humans; Injections; Ischium; Lidoc | 1993 |
How to reduce the discomfort caused by local anaesthetics.
Topics: Anesthetics, Local; Humans; Lidocaine; Pain | 1993 |
Caines produce pain.
Topics: Administration, Topical; Anesthesia, Local; Humans; Injections; Lidocaine; Orbit; Pain | 1993 |
Combined stellate ganglion and sphenopalatine ganglion block in acute herpes infection.
Topics: Autonomic Nerve Block; Bupivacaine; Female; Ganglia, Parasympathetic; Herpes Zoster Ophthalmicus; Hu | 1993 |
[Transdermal application of 10% lidocaine-gel for management of pain associated with herpes zoster].
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Female; Gels; Herpes Zoster; Humans; Lido | 1993 |
Dermal anaesthesia: comparison of EMLA cream with iontophoretic local anaesthesia.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Drug Combinations; Epinephrine; Female; Humans; Inject | 1993 |
Comparison of pentobarbital alone and pentobarbital in combination with lidocaine for euthanasia of dogs.
Topics: Animals; Dogs; Drug Combinations; Drug Synergism; Electrocardiography; Euthanasia; Female; Injection | 1993 |
Scorpion sting on the penis.
Topics: Animals; Humans; Lidocaine; Male; Middle Aged; Pain; Penis; Scorpion Stings; Scorpions | 1993 |
Tail-pinch induced analgesia and immobility: altered responses to noxious tail-pinch by prior pinch of the neck.
Topics: Analgesia; Animals; Lidocaine; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Neck; Nocicep | 1993 |
Rationalising venous cannulation: patient factors and lignocaine efficacy.
Topics: Adolescent; Adult; Age Factors; Anesthesia, Local; Catheterization, Peripheral; Female; Humans; Lido | 1993 |
Pain, punctures, and pediatricians.
Topics: Adult; Age Factors; Anesthesia, Local; Child; Child, Preschool; Emergency Medicine; Emergency Servic | 1993 |
A comparison of percutaneous and perconjunctival routes of administration of peri-ocular anaesthesia for day case cataract surgery.
Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Local; Cataract Extraction; Conjunctiva; Day Care, | 1993 |
Chronic catheterization of the epidural space in rabbits: a model for behavioural and histopathological studies. Examination of meptazinol neurotoxicity.
Topics: Animals; Behavior, Animal; Catheterization; Drug Tolerance; Female; Injections, Epidural; Lidocaine; | 1993 |
Lidocaine and no carrier fluid for the prevention of pain due to injection of propofol.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Humans; Injections, Intraveno | 1996 |
The central nucleus of the amygdala contributes to the production of morphine antinociception in the rat tail-flick test.
Topics: Amygdala; Animals; Dose-Response Relationship, Drug; Hot Temperature; Lidocaine; Male; Morphine; N-M | 1995 |
Derivation and cross-validation of pharmacokinetic parameters for computer-controlled infusion of lidocaine in pain therapy.
Topics: Adult; Anesthetics, Local; Computers; Female; Humans; Infusion Pumps; Lidocaine; Male; Middle Aged; | 1996 |
Reducing the pain on injection of propofol.
Topics: Alfentanil; Humans; Injections, Intravenous; Lidocaine; Pain; Pharmaceutical Vehicles; Propofol | 1996 |
Usefulness of a clinical scoring system to anticipate difficulty of Norplant removal.
Topics: Anesthetics, Local; Contraceptives, Oral, Synthetic; Drug Implants; Female; Humans; Levonorgestrel; | 1995 |
Heated lidocaine.
Topics: Anesthetics, Local; Buffers; Drug Stability; Hot Temperature; Humans; Hydrogen-Ion Concentration; Li | 1996 |
[Therapeutic trials with topical capsaicin cream and iontophoretically applied lidocaine for diabetic painful truncal neuropathy].
Topics: Capsaicin; Diabetic Neuropathies; Humans; Hyperesthesia; Iontophoresis; Lidocaine; Male; Middle Aged | 1996 |
Minimizing the pain of venipuncture.
Topics: Anesthetics, Local; Child; Drug Combinations; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combinat | 1996 |
Painful calf, moving foot.
Topics: Dystonia; Electromyography; Female; Foot; Ganglia, Spinal; Humans; Intervertebral Disc Displacement; | 1996 |
[Pain in lumbar puncture. Results of a 2-year discussion at the French Society of Pediatric Oncology].
Topics: Anesthetics, Local; Child; Drug Combinations; Humans; Hypnotics and Sedatives; Lidocaine; Lidocaine, | 1996 |
Oculoplastic surgery pearl. A procedure to decrease discomfort in blepharoptosis surgery.
Topics: Anesthesia, Local; Anesthetics, Local; Blepharoptosis; Drug Therapy, Combination; Epinephrine; Eyeli | 1995 |
Effects of local anaesthesia on formalin-induced Fos expression in the rat dorsal horn.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Felypressin; Formaldehyde; Ganglia, Spinal; Hemostat | 1995 |
[Cancer pain: beneficial effect of ketamine addition to spinal administration of morphine-clonidine-lidocaine mixture].
Topics: Aged; Analgesics; Catheters, Indwelling; Clonidine; Drug Combinations; Drug Synergism; Female; Human | 1996 |
Bilateral severe pain at L3-4 after spinal anaesthesia with hyperbaric 5% lignocaine.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Humans; Leg; Lidocaine; Lumbosacral Region; Male; Pain | 1996 |
Transient radicular irritation after single subarachnoid injection of isobaric 2% lignocaine for spinal anaesthesia.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Female; Genitalia, Female; Humans; Lidocaine; Middle | 1996 |
Which structures are sensitive to painful transcranial electric stimulation?
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Drug Combinations; Electric Stimulation; | 1995 |
Lignocaine for acute phantom limb pain reactivation by regional anaesthesia.
Topics: Anesthesia, Conduction; Anesthetics, Local; Humans; Injections, Intravenous; Lidocaine; Pain; Phanto | 1996 |
Pericardial sclerosis as the primary management of malignant pericardial effusion and cardiac tamponade.
Topics: Adult; Aged; Anesthetics, Local; Anti-Bacterial Agents; Arrhythmias, Cardiac; Bacterial Infections; | 1996 |
Circumcision without tears.
Topics: Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Male; Nerve Block; Pain | 1996 |
EMLA cream for renal extracorporeal shock wave lithotripsy in ambulatory patients.
Topics: Ambulatory Care; Analgesia; Analgesics, Opioid; Anesthetics, Local; Drug Combinations; Female; Fenta | 1996 |
Regional variations in skin perfusion and skin thickness may contribute to varying efficacy of topical, local anaesthetics in neonates.
Topics: Anesthesia, Local; Anesthetics, Local; Blood Specimen Collection; Drug Combinations; Female; Forehea | 1996 |
The effects of systemic procaine, lidocaine and dimethocaine on nociception in mice.
Topics: Acetic Acid; Aminobenzoates; Anesthetics, Local; Animals; Hot Temperature; Injections, Subcutaneous; | 1996 |
Cortical facilitatory action on centralis lateralis thalamic activity during the development of carrageenin-produced inflammation.
Topics: Acute Disease; Afferent Pathways; Anesthetics, Local; Animals; Carrageenan; Chronic Disease; Edema; | 1996 |
Potentiation of local lignocaine-induced sensory block by calcium channel blockers in rats.
Topics: Anesthetics, Local; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Synerg | 1996 |
Skin blood flow disturbances in the contralateral limb in a peripheral mononeuropathy in the rat.
Topics: Animals; Capsaicin; Cold Temperature; Electric Stimulation; Functional Laterality; Hindlimb; Lidocai | 1996 |
Diagnostic obturator nerve block for inguinal and back pain: a recovered opinion.
Topics: Back Pain; Bupivacaine; Electrodiagnosis; Female; Groin; Hip Joint; Humans; Injections, Intra-Articu | 1996 |
Effects of local anaesthetics on carrageenan-evoked inflammatory nociceptive processing in the rat.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Edema; Inflammation; Lidocaine; Male; Nocicep | 1996 |
[Pain in the lower extremities after subarachnoid block with lidocaine].
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Female; Humans; Leg; Lidocaine; Male; Middle Aged; Ne | 1996 |
Using local anesthetics to control procedural pain.
Topics: Anesthetics, Local; Humans; Lidocaine; Male; Pain; Surgical Procedures, Operative | 1997 |
Reducing the pain of lidocaine.
Topics: Buffers; Humans; Injections, Intradermal; Lidocaine; Pain | 1997 |
Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the rat spinal cord: studies with remifentanil and lidocaine.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Bupivacaine; Formaldehyde; Immunohistochemistry; Li | 1997 |
Supraspinal influence on hindlimb withdrawal thresholds and mustard oil-induced secondary allodynia in rats.
Topics: Animals; Brain Mapping; Hindlimb; Lidocaine; Male; Medulla Oblongata; Microinjections; Mustard Plant | 1997 |
Circumcision circumspection.
Topics: Analgesia; Anesthetics, Local; Circumcision, Male; Humans; Lidocaine; Male; Pain; Prilocaine; Urinar | 1997 |
Neonatal circumcision.
Topics: Anesthesia, Local; Anesthetics, Local; Circumcision, Male; Drug Combinations; Humans; Infant, Newbor | 1997 |
Neonatal circumcision.
Topics: Anesthetics, Local; Circumcision, Male; Drug Combinations; Humans; Infant, Newborn; Lidocaine; Lidoc | 1997 |
Trigeminal autonomic pathways involved in nociception-induced reflex cardiovascular responses.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Cobalt; Electric Stimulation; Functional Laterali | 1997 |
Patients can be pain-free while undergoing implanted port assessment.
Topics: Anesthetics, Local; Catheterization, Central Venous; Catheters, Indwelling; Drug Combinations; Human | 1997 |
[The diagnosis and treatment of anserine and trochanteric bursitis].
Topics: Anesthetics, Local; Bursitis; Diagnosis, Differential; Female; Hip Joint; Humans; Injections, Intra- | 1997 |
Analgesia during circumcision.
Topics: Analgesia; Anesthetics, Local; Circumcision, Male; Double-Blind Method; Drug Combinations; Humans; I | 1997 |
Antinociceptive interaction of intrathecal alpha2-adrenergic agonists, tizanidine and clonidine, with lidocaine in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Blood Pressure | 1997 |
Pain associated with 2% lignocaine epidural anaesthesia.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Lidocaine; Pain; | 1997 |
Intravenous lidocaine: effects on controlling pain after anti-GD2 antibody therapy in children with neuroblastoma--a report of a series.
Topics: Antibodies, Monoclonal; Child; Child, Preschool; Female; Gangliosides; Humans; Infusions, Intravenou | 1997 |
Use of differential normal pulse voltammetry for the measurement of locus coeruleus catecholaminergic metabolism in an acute anaesthetized rodent model of allodynia: effect of mexiletine.
Topics: Anesthesia; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Catecholamines; Electrodes, Implant | 1997 |
Sub-anesthetic doses of bupivacaine or lidocaine increase peripheral ICS-205 930-induced analgesia against inflammatory pain in rats.
Topics: Analgesia; Anesthetics, Local; Animals; Bupivacaine; Drug Synergism; Indoles; Inflammation; Lidocain | 1997 |
Dilute lidocaine ankle blocks in the diagnosis of sympathetically maintained pain.
Topics: Adult; Aged; Anesthetics, Local; Ankle; Female; Humans; Lidocaine; Male; Middle Aged; Nerve Block; P | 1997 |
Warming lignocaine reduces the pain of injection during local anaesthetic eyelid surgery.
Topics: Anesthetics, Local; Eyelids; Hot Temperature; Humans; Lidocaine; Pain | 1997 |
Pain during circumcision.
Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Circumcision, Male; Humans; Infant, Ne | 1997 |
QX-314 inhibits ectopic nerve activity associated with neuropathic pain.
Topics: Action Potentials; Anesthetics, Local; Animals; Blood Pressure; Heart Rate; Lidocaine; Male; Pain; R | 1997 |
Comparison of the effects of treatment with intrathecal lidocaine given before and after formalin on both nociception and Fos expression in the spinal cord dorsal horn.
Topics: Anesthetics, Local; Animals; Formaldehyde; Lidocaine; Male; Pain; Proto-Oncogene Proteins c-fos; Rat | 1998 |
Comparison of methods for the reduction of acute pain produced by rubber ring castration or tail docking of week-old lambs.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Hydrocortisone; Injections, Subcutaneous; Lidocaine; | 1998 |
Lignocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy.
Topics: Anesthetics, Local; Cystoscopy; Gels; Humans; Lidocaine; Pain | 1998 |
Antinociception following opioid stimulation of the basolateral amygdala is expressed through the periaqueductal gray and rostral ventromedial medulla.
Topics: Amygdala; Analgesics, Opioid; Anesthetics, Local; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enke | 1998 |
Utility of EMLA in the relief of pain associated with electroneurography.
Topics: Administration, Topical; Adult; Anesthetics, Local; Electric Stimulation; Electromyography; Facial N | 1998 |
Systemic lidocaine induces expansion of the receptive field of spinal dorsal horn neurons in rats.
Topics: Anesthetics, Local; Animals; Evoked Potentials; Female; Hindlimb; Injections, Intravenous; Lidocaine | 1998 |
A surgically placed epidural catheter in a patient with spinal trauma.
Topics: Accidents, Traffic; Adolescent; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, General; Anes | 1998 |
Pharmacological and neuroanatomical evidence for the involvement of the anterior pretectal nucleus in the antinociception induced by stimulation of the dorsal raphe nucleus in rats.
Topics: Afferent Pathways; Amidines; Anesthetics, Local; Animals; Electric Stimulation; Fluorescent Dyes; Li | 1998 |
Tumescent infiltration of corticosteroids, lidocaine, and epinephrine into dermatomes of acute herpetic pain or postherpetic neuralgia.
Topics: Acute Disease; Anesthetics, Local; Epinephrine; Glucocorticoids; Herpes Zoster; Humans; Injections; | 1998 |
Lessening the pain of lidocaine injection.
Topics: Adult; Anesthetics, Local; Buffers; Humans; Injections, Subcutaneous; Lidocaine; Pain; Prospective S | 1998 |
The cold plate as a test of nociceptive behaviors: description and application to the study of chronic neuropathic and inflammatory pain models.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Chronic Disease; Clonidine; Cold | 1998 |
[Pain-free circumcision].
Topics: Anesthetics, Combined; Circumcision, Male; Heart Rate; Humans; Infant, Newborn; Lidocaine; Lidocaine | 1998 |
No negative influence of EMLA application prior to BCG vaccination.
Topics: Anesthetics, Combined; Anesthetics, Local; BCG Vaccine; Child; Child, Preschool; Female; Humans; Inf | 1998 |
Sevoflurane suppresses behavioral response in the rat formalin test: combination with intrathecal lidocaine produced profound suppression of the response.
Topics: Anesthetics, Inhalation; Anesthetics, Local; Animals; Behavior, Animal; Drug Synergism; Formaldehyde | 1998 |
Pain on injection of propofol.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Humans; Lidocaine; Pain; Propofol | 1998 |
Does intravenous administration of GABA(A) receptor antagonists induce both descending antinociception and touch-evoked allodynia?
Topics: Analgesics; Anesthetics, Local; Animals; Brain Mapping; Cats; Decerebrate State; Electrophysiology; | 1998 |
[Inguinal pain caused by iliopsoas bursitis].
Topics: Aged; Anesthetics; Bursitis; Female; Groin; Hip Joint; Humans; Lidocaine; Male; Middle Aged; Pain; R | 1998 |
Painful pricks.
Topics: Anesthetics, Local; Child; Child, Preschool; Female; Humans; India; Infant; Infant, Newborn; Injecti | 1998 |
Reducing the pain of local anesthetic infiltration: results of a national clinical practice survey.
Topics: Anesthetics, Local; Buffers; Emergency Medicine; Hot Temperature; Humans; Injections, Subcutaneous; | 1998 |
Ring block for neonatal circumcision.
Topics: Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Pain | 1998 |
Nasal manipulation with intravenous sedation. Is it an acceptable and effective treatment?
Topics: Administration, Intranasal; Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Conscious Seda | 1998 |
[Groin pain due to iliopectineal bursitis].
Topics: Adult; Bursitis; Groin; Humans; Ilium; Injections; Lidocaine; Male; Pain; Ultrasonography | 1998 |
The effects of local anesthetics on postoperative pain.
Topics: Adult; Anesthetics, Local; Bupivacaine; Hernia, Inguinal; Humans; Intraoperative Period; Lidocaine; | 1998 |
Pain analysis in prediction of treatment outcome.
Topics: Adenosine; Analgesics; Analgesics, Opioid; Anesthetics, Local; Dose-Response Relationship, Drug; Dru | 1998 |
Spinal antinociceptive action of Na+-K+ pump inhibitor ouabain and its interaction with morphine and lidocaine in rats.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Animals; Drug Interactions; Enzyme Inhibitors; L | 1999 |
Alleviation of the pain of venepuncture in neonates.
Topics: Anesthetics, Local; Hand; Heel; Humans; Infant, Newborn; Lidocaine; Lidocaine, Prilocaine Drug Combi | 1999 |
Bilateral buttock and leg pain after lidocaine epidural anesthesia.
Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Buttocks; Female; Humans; Leg; Lidocaine; Pain | 1999 |
Treatment of pain in adiposis dolorosa (Dercum's disease) with intravenous lidocaine: a case report with a 10-year follow-up.
Topics: Adiposis Dolorosa; Anesthetics, Local; Drug Administration Schedule; Female; Follow-Up Studies; Huma | 1999 |
Use of topical lidocaine in pediatric laceration repair.
Topics: Anesthetics, Local; Child; Ethics, Medical; Humans; Lidocaine; Pain; Research Design; United States; | 1999 |
Analgesia for spinal puncture.
Topics: Analgesia; Anesthetics, Local; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain; Pril | 1999 |
Epidural analgesia for labor pain is not associated with a decreased frequency of uterine activity.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca | 1999 |
Behavioural, endocrine and cardiac responses in young calves undergoing dehorning without and with use of sedation and analgesia.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Local; Animals; Butorphanol; Cattle; Ele | 1999 |
Relative effectiveness of lignocaine-prilocaine emulsion and nitrous oxide inhalation for routine preoperative laboratory testing.
Topics: Adult; Age Factors; Analysis of Variance; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetic | 1999 |
The non-NMDA glutamate receptor antagonist CNQX augments lidocaine antinociception through a spinal action in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Colon; Drug Synergism; Excitatory | 1999 |
Treatment of painful distal sensory polyneuropathy in HIV-infected patients with a topical agent: results of an open-label trial of 5% lidocaine gel.
Topics: Anesthetics, Local; Clinical Trials as Topic; HIV Infections; Humans; Lidocaine; Pain; Peripheral Ne | 1999 |
Anesthetic dose and analgesic effects of sub-Tenon's anesthesia in cataract surgery.
Topics: Aged; Analgesia; Anesthesia, Local; Anesthetics, Local; Conjunctiva; Connective Tissue; Female; Huma | 1999 |
[Behavior of piglets during castration with and without local anesthesia].
Topics: Anesthesia, Local; Animal Welfare; Animals; Germany; Lidocaine; Male; Orchiectomy; Pain; Pain Measur | 1999 |
Membrane potential oscillations in dorsal root ganglion neurons: role in normal electrogenesis and neuropathic pain.
Topics: Afferent Pathways; Animals; Axons; Electric Stimulation; Female; Ganglia, Spinal; Lidocaine; Male; M | 1999 |
[Use of EMLA Creme in leg ulcers: usefulness and limits].
Topics: Anesthetics, Combined; Anesthetics, Local; Debridement; Humans; Leg Ulcer; Lidocaine; Lidocaine, Pri | 1999 |
Repetitive pinching of the skin during lidocaine infiltration reduces patient discomfort.
Topics: Anesthetics, Local; Humans; Injections, Intradermal; Lidocaine; Pain; Pain Threshold; Skin; Touch | 1999 |
[Paraspinal muscle spasm].
Topics: Accidental Falls; Adolescent; Female; Humans; Lidocaine; Lumbosacral Region; Muscle, Skeletal; Pain; | 1996 |
Comparative study of distraction versus topical anesthesia for pediatric pain management during immunizations.
Topics: Anesthetics, Local; Anxiety; Child; Child Behavior; Female; Humans; Immunization; Lidocaine; Lidocai | 1999 |
New skin patch calms pain following shingles.
Topics: Administration, Cutaneous; Anesthetics, Local; Herpes Zoster; Humans; Lidocaine; Pain | 2000 |
Successful treatment of reflex sympathetic dystrophy by bier block with lidocaine and clonidine.
Topics: Adult; Anesthesia, Conduction; Anesthetics, Local; Cardiography, Impedance; Clonidine; Female; Human | 1999 |
[Idiopathic entrapment neuropathy of the ilio-inguinalis nerve--a differential diagnosis in inguinal pain].
Topics: Adult; Anesthetics, Local; Humans; Inguinal Canal; Lidocaine; Male; Nerve Compression Syndromes; Pai | 2000 |
Lidocaine patch 5%.
Topics: Absorption; Administration, Cutaneous; Anesthetics, Local; Herpes Zoster; Humans; Lidocaine; Neuralg | 2000 |
Use of a eutectic mixture of local anesthesia in newborns.
Topics: Anesthetics, Local; Drug Combinations; Emulsions; Humans; Infant; Infant, Newborn; Lidocaine; Pain; | 1999 |
[Emla cream in pediatric emergency cases by using selection criteria. Feasibility study].
Topics: Anesthetics, Local; Child; Child Welfare; Emergency Medical Services; Feasibility Studies; Humans; L | 2000 |
Amino acid release into the knee joint: key role in nociception and inflammation.
Topics: Amino Acids; Anesthetics, Local; Animals; Arginine; Arthritis; Carrageenan; Chromatography, High Pre | 2000 |
Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats.
Topics: Anesthetics, Local; Animals; Antibodies, Blocking; Dizocilpine Maleate; Dynorphins; Excitatory Amino | 2000 |
Analgesic effects of sub-Tenon's versus retrobulbar anesthesia in planned extracapsular cataract extraction.
Topics: Acetylcholine; Aged; Analgesia; Anesthesia, Local; Anesthetics, Local; Cataract Extraction; Choliner | 2000 |
[The predictive lidocaine test in treatment of neuropathic pain].
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Pa | 2000 |
The 'three in one' block as locoregional analgesia in an emergency department.
Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Combinations; Emergency Treatment; | 2000 |
Intravenous lidocaine inhibits visceral nociceptive reflexes and spinal neurons in the rat.
Topics: Anesthetics, Local; Animals; Blood Pressure; Colon; Dilatation, Pathologic; Electrophysiology; Heart | 2000 |
Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice.
Topics: Animals; Carbamazepine; Clonidine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Dru | 2000 |
[Isobaric 2% lidocaine in continuous subarachnoid anesthesia using microcatheters].
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Catheterization; Drug Administration Schedule; Electiv | 2000 |
Does the temperature of lignocaine hydrochloride gel affect instillation discomfort in the male urethra?
Topics: Cold Temperature; Gels; Humans; Lidocaine; Male; Pain; Urethra | 2000 |
The rectal administration of lidocaine gel and tolerance of transrectal ultrasonography-guided biopsy of the prostate: a prospective randomized placebo-controlled study.
Topics: Administration, Rectal; Biopsy, Needle; Gels; Humans; Lidocaine; Pain; Pain Measurement; Prospective | 2000 |
Perfusion of the mechanically compressed lumbar ganglion with lidocaine reduces mechanical hyperalgesia and allodynia in the rat.
Topics: Anesthetics, Local; Animals; Ganglia, Spinal; Hyperalgesia; Infusion Pumps, Implantable; Lidocaine; | 2000 |
EMLA for circumcision?
Topics: Anesthetics, Local; Child Advocacy; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocain | 2000 |
Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat.
Topics: Anesthetics, Local; Animals; Benzodiazepinones; Cholecystokinin; Hot Temperature; Hyperalgesia; Lido | 2000 |
Arm pain as an unusual presentation of postdural puncture intracranial hypotension.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Blood Patch, Epidural; Dilatation and Curettage; Dura | 2000 |
Lidocaine + prilocaine before 3 months of age: new indication. Correct use is crucial.
Topics: Administration, Cutaneous; Age Factors; Blood Specimen Collection; Circumcision, Male; Drug Therapy, | 2000 |
The anterior pretectal nucleus participates as a relay station in the glutamate-, but not morphine-induced antinociception from the dorsal raphe nucleus in rats.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Animals; Basal Ganglia; Glutamic Acid; Lidocaine | 2000 |
Systemic naloxone enhances cerebral blood flow in anesthetized morphine-dependent rats.
Topics: Anesthesia; Anesthetics, Local; Animals; Brain; Cerebrovascular Circulation; Diarrhea; Lidocaine; Ma | 2000 |
The pediatric forum: pain indication in circumcision.
Topics: Anesthetics, Local; Circumcision, Male; Humans; Infant, Newborn; Lidocaine; Lidocaine, Prilocaine Dr | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Effectiveness of local anesthesia in pediatric dental practice.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Child; Child, Pre | 2000 |
Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Implants; Drug Tolerance; Hot Temperatur | 2001 |
Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Implants; Drug Tolerance; Hot Temperatur | 2001 |
Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Implants; Drug Tolerance; Hot Temperatur | 2001 |
Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Implants; Drug Tolerance; Hot Temperatur | 2001 |
Antinociceptive interaction between spinal clonidine and lidocaine in the rat formalin test: an isobolographic analysis.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Calcium Channels; Clonidine; Dose-Response R | 2001 |
Topical anesthesia for phacoemulsification and painless subconjunctival antibiotic injection.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Antibiotic Prophylaxis; Cefuroxime; Cephalosporins; Con | 2001 |
Reducing pain during hair transplant lidocaine infiltration.
Topics: Anesthetics, Local; Hair; Humans; Lidocaine; Pain; Vibration | 2001 |
Influence of ophthalmic viscosurgical device on the effects of intracameral anesthesia and stains.
Topics: Anesthesia, Local; Anesthetics, Local; Humans; Lidocaine; Pain; Pain Measurement; Palliative Care; P | 2001 |
The lidocaine patch.
Topics: Anesthetics, Local; Drug Administration Schedule; Evidence-Based Medicine; Herpes Zoster Oticus; Hum | 2001 |
Factors affecting patients' and potential patients' choices among anaesthetics for periodontal recall visits.
Topics: Administration, Topical; Adult; Anesthesia, Dental; Anesthetics, Local; Attitude to Health; Choice B | 2001 |
Gray ramus communicans nerve block: novel treatment approach for painful osteoporotic vertebral compression fracture.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Drug Combinations; Female; Fl | 2001 |
Alkalinized intravesical lidocaine to treat interstitial cystitis: absorption kinetics in normal and interstitial cystitis bladders.
Topics: Administration, Intravesical; Anesthetics, Local; Buffers; Cystitis, Interstitial; Humans; Lidocaine | 2001 |
Hot chili, a cook and EMLA.
Topics: Anesthetics, Local; Capsaicin; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain; Pril | 2001 |
Pain control and the apprehensive patient.
Topics: Administration, Topical; Anesthetics, Local; Dental Anxiety; Dentist-Patient Relations; Humans; Inje | 2001 |
[Suture of skin lacerations using LAT gel (lidocaine, adrenaline, tetracaine)].
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Child; Child, Preschool; Dermatologic Surgical Procedur | 2001 |
Re: A randomized prospective trial of intrarectal lidocaine for pain control during transrectal prostate biopsy: the Emory University experience.
Topics: Administration, Rectal; Anesthetics, Local; Biopsy; Humans; Lidocaine; Male; Pain; Prospective Studi | 2001 |
Periprostatic local anesthesia before ultrasound-guided prostate biopsy: an update of the miami experience.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Biopsy; Humans; Lidocaine; Male; Middle Aged; Pa | 2001 |
Re: reduction in pain associated with open carpal tunnel decompression.
Topics: Anesthetics, Local; Carpal Tunnel Syndrome; Decompression, Surgical; Humans; Injections; Lidocaine; | 2001 |
Flexible cystodiathermy can be rendered painless by using 2% lignocaine solution to provide intravesical anaesthesia.
Topics: Administration, Intravesical; Anesthetics, Local; Chlorhexidine; Cystoscopy; Diathermy; Drug Combina | 2001 |
[New uses of EMLA: anesthesia for relief of pain caused by hemorrhoid thrombosis].
Topics: Adult; Anesthetics, Combined; Female; Hemorrhoids; Humans; Lidocaine; Lidocaine, Prilocaine Drug Com | 2001 |
Physiological characteristics of the projection pathway from the medial preoptic to the nucleus raphe magnus of the rat and its modulation by the periaqueductal gray.
Topics: Anesthetics, Local; Animals; Electric Stimulation; Glutamic Acid; Lidocaine; Male; Neural Pathways; | 2001 |
Development of a behavioral model of TMJ pain in rats: the TMJ formalin test.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Disease Models, Animal; Lidocaine | 2001 |
Diagnosis and management of transient neurologic symptoms following subarachnoid block with single-shot isobaric 2% lidocaine.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Female; Humans; Lidocaine; Pain; Spinal Cord; Subarach | 2001 |
[Corticosteroid injection for coccygodynia].
Topics: Adrenal Cortex Hormones; Adult; Anesthetics, Local; Coccyx; Female; Follow-Up Studies; Humans; Injec | 2001 |
NSAID reduction through alternative pain-management programs.
Topics: Administration, Topical; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans | 2001 |
Topical pharyngeal anesthesia during gastroscopy.
Topics: Anesthesia, Local; Anesthetics, Local; Anxiety; Gastroscopy; Humans; Larynx; Lidocaine; Midazolam; P | 2001 |
A single injection of lidocaine as local anesthesia for ultrasound guided needle biopsy of the prostate.
Topics: Anesthetics, Local; Biopsy, Needle; Humans; Hypnotics and Sedatives; Injections; Lidocaine; Male; Mi | 2002 |
Evidence for two populations of rat spinal dorsal horn neurons excited by urinary bladder distension.
Topics: Action Potentials; Analgesics, Opioid; Anesthetics, Local; Animals; Catheterization; Decerebrate Sta | 2001 |
A human oral capsaicin pain model to assess topical anesthetic-analgesic drugs.
Topics: Administration, Topical; Adult; Anesthetics, Local; Capsaicin; Female; Genetic Variation; Humans; Li | 2001 |
Lidocaine patch for pain of erythromelalgia.
Topics: Administration, Cutaneous; Adolescent; Delayed-Action Preparations; Erythromelalgia; Female; Follow- | 2002 |
[Anterior iliopsoas impingement after total hip arthroplasty: diagnosis and conservative treatment in 9 cases].
Topics: Adrenal Cortex Hormones; Adult; Anesthetics, Local; Arthroplasty, Replacement, Hip; Female; Groin; H | 2001 |
The relationship between propagated contractions and pseudoaffective changes in blood pressure in response to intestinal distension.
Topics: Adrenergic alpha-Antagonists; Affect; Anesthetics, Local; Animals; Blood Pressure; Capsaicin; Heart | 2001 |
Local anaesthetic endonasal endoscopic laser dacryocystorhinostomy: analysis of patients' acceptability and various factors affecting the success of this procedure.
Topics: Administration, Topical; Adrenergic Agonists; Aged; Anesthesia, Local; Anesthetics, Local; Cocaine; | 2002 |
Lidocaine gel greatly reduces pain for men undergoing rectal prostate biopsy.
Topics: Administration, Rectal; Anesthetics, Local; Biopsy, Needle; Gels; Humans; Lidocaine; Male; Pain; Pai | 2001 |
Second phase of formalin-induced excitation of spinal dorsal horn neurons in spinalized rats is reversed by sciatic nerve block.
Topics: Action Potentials; Afferent Pathways; Anesthetics, Local; Animals; Lidocaine; Male; Nerve Block; Neu | 2002 |
[Management of leg ulcers in the elderly].
Topics: Age Distribution; Aged; Anesthetics, Local; Bandages; Debridement; Humans; Leg Ulcer; Lidocaine; Lid | 2002 |
Registered nurses' choices regarding the use of intradermal lidocaine for intravenous insertions: the challenge of changing practice.
Topics: Anesthetics, Local; Attitude of Health Personnel; Catheterization, Peripheral; Choice Behavior; Clin | 2002 |
Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain.
Topics: Animals; Behavior, Animal; Denervation; Dynorphins; Immunotoxins; Kinetics; Lidocaine; Ligation; Mal | 2002 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Tape stripping the stratum corneum and the effectiveness of EMLA.
Topics: Anesthetics, Local; Child, Preschool; Evidence-Based Medicine; Humans; Lidocaine; Lidocaine, Priloca | 2002 |
Medijector--a new method of corticosteroid-anesthetic delivery.
Topics: Anesthetics, Local; Dexamethasone; Drug Therapy, Combination; Glucocorticoids; Humans; Injections, J | 1979 |
Relieving pain with nerve blocks.
Topics: Acute Disease; Aged; Back Pain; Bursitis; Humans; Intervertebral Disc; Joint Diseases; Lidocaine; Mi | 1978 |
The myofascial syndrome.
Topics: Humans; Lidocaine; Neck; Pain; Shoulder; Temporomandibular Joint Dysfunction Syndrome | 1979 |
Sensitivity of cutaneous cold fibers to noxious heat: paradoxical cold discharge.
Topics: Animals; Body Temperature; Cold Temperature; Evoked Potentials; Haplorhini; Hot Temperature; Lidocai | 1977 |
The effects of diazepam, morphine and lidocaine on nociception in rhesus monkeys: a signal detection analysis.
Topics: Animals; Diazepam; Discrimination, Psychological; Electric Stimulation; Escape Reaction; Haplorhini; | 1978 |
Pain of first-trimester abortion: its quantification and relations with other variables.
Topics: Abortion, Induced; Anesthesia, Local; Diazepam; Evaluation Studies as Topic; Female; Humans; Lidocai | 1979 |
Pain of first-trimester abortion: its quantification and relations with other variables.
Topics: Abortion, Induced; Anesthesia, Local; Diazepam; Evaluation Studies as Topic; Female; Humans; Lidocai | 1979 |
Pain of first-trimester abortion: its quantification and relations with other variables.
Topics: Abortion, Induced; Anesthesia, Local; Diazepam; Evaluation Studies as Topic; Female; Humans; Lidocai | 1979 |
Pain of first-trimester abortion: its quantification and relations with other variables.
Topics: Abortion, Induced; Anesthesia, Local; Diazepam; Evaluation Studies as Topic; Female; Humans; Lidocai | 1979 |
Trochanteric bursitis: a common cause of pelvic girdle pain.
Topics: Bursitis; Diagnosis, Differential; Hip; Humans; Hydrocortisone; Lidocaine; Pain; Pelvic Bones; Radio | 1979 |
Semimembranosus insertion syndrome: a treatable and frequent cause of persistent knee pain.
Topics: Adrenal Cortex Hormones; Adult; Aged; Female; Follow-Up Studies; Humans; Injections, Intra-Articular | 1979 |
New low osmolality water-soluble contrast compounds in selective arteriography of the peripheral limbs. A comparative study.
Topics: Angiography; Contrast Media; Humans; Lidocaine; Meglumine; Metrizamide; Metrizoic Acid; Osmolar Conc | 1979 |
The use of xylocaine to diminish leg cramps in venography.
Topics: Contrast Media; Double-Blind Method; Drug Combinations; Evaluation Studies as Topic; Humans; Leg; Li | 1979 |
Intravenous lidocaine: an effective analgesic for lower extremity venography.
Topics: Contrast Media; Drug Combinations; Humans; Leg; Lidocaine; Pain; Phlebography | 1979 |
Segmental epidural analgesia for labor and delivery.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Pressure; Bupivacaine; Drug Evaluation; Female; | 1979 |
[Pharmacological studies on the antiphlogistic effect of pentosanpolysulfate in combination with metamizol].
Topics: Aminopyrine; Animals; Arthritis, Rheumatoid; Dipyrone; Drug Combinations; Drug Evaluation, Preclinic | 1977 |
Painful peripheral states and sympathetic blocks.
Topics: Anesthesia, Local; Bupivacaine; Central Nervous System Diseases; Differential Threshold; Female; Gua | 1978 |
[The intra-arterial use of lidocaine to reduce pain in aorto-femoral arteriography (author's transl)].
Topics: Adult; Aged; Aortography; Femoral Artery; Humans; Injections, Intra-Arterial; Lidocaine; Middle Aged | 1978 |
The use of microsurgical denervation of the spermatic cord for orchialgia.
Topics: Abdomen; Adult; Denervation; Hernia, Inguinal; Humans; Lidocaine; Male; Meperidine; Microsurgery; Pa | 1978 |
Pain and temperature sensations related to local analgesia.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Body Temperature; Female; Humans; Lidocaine; Male; Mep | 1975 |
[Sphincter surgery. Etiology and therapy of the anal fissure (author's transl)].
Topics: Adolescent; Adult; Anal Canal; Constipation; Female; Fissure in Ano; Humans; Lidocaine; Male; Middle | 1976 |
Xylocaine visous for diagnosis of chest pain.
Topics: Diagnosis, Differential; Humans; Lidocaine; Methods; Myocardial Infarction; Pain; Thorax | 1977 |
Abdominal pain of spinal origin. Value of intercostal block.
Topics: Abdomen; Adolescent; Adult; Aged; Child; Female; Humans; Intercostal Nerves; Lidocaine; Male; Middle | 1977 |
Intra-arterial lidocaine: an effective analgesic for peripheral angiography.
Topics: Angiography; Contrast Media; Diatrizoate Meglumine; Female; Femoral Artery; Humans; Injections, Intr | 1977 |
The painful arc syndrome. Clinical classification as a guide to management.
Topics: Acromioclavicular Joint; Female; Humans; Joint Diseases; Lidocaine; Ligaments, Articular; Male; Midd | 1977 |
Pharmacological modulations on the nociceptive flexion reflex in man.
Topics: Adult; Aspirin; Electric Stimulation; Female; Humans; Leg; Lidocaine; Male; Meperidine; Muscles; Nap | 1977 |
The use of sacral nerve blocks in the evaluation and treatment of neurologic bladder disease.
Topics: Humans; Lidocaine; Lumbosacral Plexus; Nerve Block; Pain; Pain Management; Pelvic Neoplasms; Phenols | 1977 |
The effects of local steroid injection for supraspinatus tears.
Topics: Adult; Aged; Analgesics; Blood Sedimentation; Female; Humans; Injections; Lidocaine; Male; Methylpre | 1977 |
Xylocaine viscous as an aid in the differential diagnosis of chest pain.
Topics: Administration, Oral; Coronary Disease; Diagnosis, Differential; Gastrointestinal Diseases; Humans; | 1976 |
A caveat for xylocaine viscous and chest pain.
Topics: Coronary Disease; Gastrointestinal Diseases; Humans; Lidocaine; Pain; Thorax | 1976 |
Clinical trials with bupivacaine in oral surgery.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Bupivacaine; Drug Evaluation; Female; Humans; Lidocaine; | 1976 |
Peroneal tenography in previous calcaneal fractures.
Topics: Cadaver; Calcaneus; Fibula; Fractures, Bone; Humans; Lidocaine; Pain; Pressure; Radiography; Tendons | 1975 |
The tonic ambulatory foot response. A clinical and electromyographic study.
Topics: Cerebrovascular Disorders; Electromyography; Female; Foot; Humans; Lidocaine; Locomotion; Male; Midd | 1975 |
An investigation in man into the relative potency of lignocaine, bupivacaine and etidocaine.
Topics: Acetanilides; Anesthetics, Local; Bupivacaine; Dose-Response Relationship, Drug; Ethylamines; Humans | 1975 |
Letter: The pain of venipuncture.
Topics: Humans; Lidocaine; Pain; Punctures; Veins | 1975 |
EEG evaluation of humaneness of asphyxia and decapitation euthanasia of the laboratory rat.
Topics: Action Potentials; Anesthesia, Inhalation; Anesthesia, Local; Animals; Asphyxia; Electrodes, Implant | 1975 |
The nonsurgical treatment of Eagle's syndrome.
Topics: Drug Therapy, Combination; Humans; Hyoid Bone; Injections; Lidocaine; Ligaments; Pain; Pharyngeal Di | 1976 |
[Does the differential block by the epidural route provide a diagnostic aid in chronic pain?].
Topics: Aged; Analgesia, Epidural; Autonomic Nerve Block; Chronic Disease; Female; Humans; Lidocaine; Male; | 1992 |
Local anesthesia in rhinoplasty: a new twist?
Topics: Adult; Anesthesia, Local; Bicarbonates; Bupivacaine; Female; Humans; Injections; Lidocaine; Male; Mi | 1992 |
pH-adjusted local anaesthetics.
Topics: Anesthesia, Local; Bicarbonates; Humans; Hydrogen-Ion Concentration; Lidocaine; Pain; Sodium; Sodium | 1992 |
ECT anaesthetics.
Topics: Contraindications; Electroconvulsive Therapy; Humans; Lidocaine; Methohexital; Pain; Propofol | 1992 |
Suppression of prostaglandin E1-induced pain by dilution of the drug with lidocaine before intracavernous injection.
Topics: Alprostadil; Erectile Dysfunction; Humans; Injections; Lidocaine; Male; Pain; Penis | 1992 |
Treatment of inflammatory, neuropathic and sympathetically maintained pain in a patient with Sjögren's syndrome.
Topics: Action Potentials; Adult; Female; Humans; Inflammation; Lidocaine; Nerve Block; Pain; Pain Managemen | 1992 |
Intravenous morphine-induced activation of vagal afferents: peripheral, spinal, and CNS substrates mediating inhibition of spinal nociception and cardiovascular responses.
Topics: Afferent Pathways; Animals; Blood Pressure; Brain; Heart Rate; Ibotenic Acid; Lidocaine; Male; Medul | 1992 |
[Changes in the pain produced by the peripheral venous injection of propofol when it is combined with lidocaine or fentanyl].
Topics: Adolescent; Adult; Aged; Child; Female; Fentanyl; Humans; Injections, Intravenous; Lidocaine; Male; | 1992 |
Onset and duration of hypoalgesia of lidocaine spray applied to oral mucosa--a dose response study.
Topics: Adult; Aerosols; Anesthesia, Local; Dose-Response Relationship, Drug; Female; Humans; Lasers; Lidoca | 1992 |
Reducing pain associated with injection of lidocaine.
Topics: Hot Temperature; Humans; Injections; Lidocaine; Pain | 1992 |
Hemodialysis needles can be pain free: use of a topical anaesthetic cream.
Topics: Administration, Topical; Anesthetics, Local; Drug Combinations; Humans; Lidocaine; Needles; Ointment | 1992 |
Relieving needle puncture pain.
Topics: Anesthetics, Local; Child; Drug Combinations; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combinat | 1992 |
Nociceptive neurons in area 24 of rabbit cingulate cortex.
Topics: Animals; Cerebral Cortex; Ear, External; Electric Stimulation; Electrodes; Electrophysiology; Inject | 1992 |
The NMDA-receptor antagonist CPP abolishes neurogenic 'wind-up pain' after intrathecal administration in humans.
Topics: Cold Temperature; Female; Hot Temperature; Humans; Injections, Spinal; Lidocaine; Middle Aged; Pain; | 1992 |
Corticosteroid injections for chronic low back pain.
Topics: Adrenal Cortex Hormones; Back Pain; Humans; Injections, Intra-Arterial; Lidocaine; Pain | 1992 |
Neutralized lidocaine: use in pain reduction in local anesthesia.
Topics: Adult; Anesthesia, Local; Buffers; Humans; Hydrogen-Ion Concentration; Injections, Intradermal; Lido | 1992 |
Bacteriostatic saline as a means of reducing the pain of injecting xylocaine.
Topics: Anesthesia, Local; Humans; Injections, Subcutaneous; Lidocaine; Pain; Sodium Chloride | 1992 |
Appropriate use of local anaesthetic for venous cannulation.
Topics: Adult; Aged; Anesthesia, Local; Catheterization, Peripheral; Female; Humans; Injections, Subcutaneou | 1992 |
The source of shoulder pain in hemiplegia.
Topics: Age Factors; Aged; Data Interpretation, Statistical; Female; Hemiplegia; Humans; Lidocaine; Male; Mi | 1992 |
Analgesia produced by lidocaine microinjection into the dentate gyrus.
Topics: Analgesics; Animals; Formaldehyde; Hippocampus; Injections, Subcutaneous; Lidocaine; Male; Microinje | 1992 |
Pain response to perineuromal injection of normal saline, epinephrine, and lidocaine in humans.
Topics: Epinephrine; Humans; Injections; Lidocaine; Neuroma; Pain; Pain Measurement; Sodium Chloride | 1992 |
[Influence of calcium channel blockers and beta-blockers on pain relief with iontophoresis].
Topics: Adult; Calcium Channel Blockers; Female; Guanethidine; Humans; Iontophoresis; Lidocaine; Male; Pain; | 1992 |
Temporal processes of formalin pain: differential role of the cingulum bundle, fornix pathway and medial bulboreticular formation.
Topics: Animals; Efferent Pathways; Formaldehyde; Gyrus Cinguli; Hippocampus; Injections; Lidocaine; Male; P | 1992 |
[Treatment of pain in diabetic polyneuropathy].
Topics: Analgesics; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Carbamaze | 1991 |
Electrocution injury.
Topics: Adolescent; Betamethasone; Electric Injuries; Foot Injuries; Humans; Hyaluronoglucosaminidase; Lidoc | 1991 |
Bleomycin-lidocaine mixture reduces pain of intralesional injection in the treatment of recalcitrant verrucae.
Topics: Anesthesia, Local; Bleomycin; Humans; Injections, Intralesional; Lidocaine; Pain; Warts | 1991 |
Analgesia versus sedation during Broviac catheter placement.
Topics: Blood Glucose; Blood Pressure; Catheterization; Epinephrine; Female; Fentanyl; Heart Rate; Humans; I | 1991 |
The management of oral mexiletine and intravenous lidocaine to treat chronic painful symmetrical distal diabetic neuropathy.
Topics: Chronic Disease; Diabetic Neuropathies; Drug Therapy, Combination; Female; Humans; Infusions, Intrav | 1991 |
On "The effect of intravenous lidocaine on nociceptive processing in diabetic neuropathy" by Bach et al. in Pain, 40 (1990) 29-34.
Topics: Diabetic Neuropathies; Humans; Injections, Intravenous; Lidocaine; Nociceptors; Pain | 1991 |
Does lignocaine temperature alter pain perception during cutaneous local anaesthesia?
Topics: Adult; Anesthesia, Local; Female; Humans; Injections, Intradermal; Lidocaine; Male; Middle Aged; Pai | 1991 |
Sphenopalatine block--the cheapest technique in the management of chronic pain.
Topics: Aerosols; Chronic Disease; Humans; Lidocaine; Nerve Block; Pain; Pain Management | 1991 |
Studies in autotomy: its pathophysiology and usefulness as a model of chronic pain.
Topics: Afferent Pathways; Animals; Behavior, Animal; Chronic Disease; Denervation; Disease Models, Animal; | 1991 |
Pain associated with peripheral infusion of carmustine.
Topics: Carmustine; Catheterization, Peripheral; Humans; Infusions, Intravenous; Lidocaine; Pain | 1991 |
Selective inhibition by systemic lidocaine of noxious evoked activity in rat dorsal horn neurons.
Topics: Animals; Evoked Potentials; Hot Temperature; Injections, Intravenous; Lidocaine; Male; Neurons; Pain | 1991 |
Lidocaine-induced spinal block can relieve central poststroke pain: role of the block in chronic pain diagnosis.
Topics: Aged; Anesthesia, Spinal; Brain; Cerebrovascular Disorders; Chronic Disease; Humans; Lidocaine; Male | 1991 |
Hyperalgesia during acute opioid abstinence: evidence for a nociceptive facilitating function of the rostral ventromedial medulla.
Topics: Animals; Lidocaine; Male; Medulla Oblongata; Microinjections; Naloxone; Nociceptors; Pain; Rats; Rat | 1991 |
Stability of buffered lidocaine and epinephrine used for local anesthesia.
Topics: Anesthesia, Local; Buffers; Drug Combinations; Drug Stability; Drug Storage; Epinephrine; Humans; Hy | 1991 |
Iontophoresis versus subcutaneous injection: a comparison of two methods of local anesthesia delivery in children.
Topics: Adolescent; Adult; Anesthetics, Local; Anxiety; Child; Female; Humans; Injections, Subcutaneous; Ion | 1991 |
Zones of differential sensory block during extradural anaesthesia.
Topics: Adult; Age Factors; Aged; Anesthesia, Epidural; Cold Temperature; Female; Humans; Lidocaine; Male; M | 1991 |
Buffered lidocaine in local anesthesia.
Topics: Anesthetics, Local; Buffers; Humans; Hydrogen-Ion Concentration; Lidocaine; Pain; Pain Measurement | 1990 |
Alkalinized lidocaine in special procedures.
Topics: Humans; Hydrogen-Ion Concentration; Lidocaine; Pain | 1990 |
Neutralized lidocaine with epinephrine for local anesthesia--II.
Topics: Anesthesia, Local; Bicarbonates; Dermatologic Surgical Procedures; Double-Blind Method; Epinephrine; | 1990 |
Painless port access.
Topics: Catheters, Indwelling; Child; Humans; Injections, Jet; Lidocaine; Pain | 1990 |
A practical approach to the painful bladder syndrome.
Topics: Administration, Intravesical; Adult; Aged; Clinical Protocols; Dilatation; Dimethyl Sulfoxide; Exerc | 1990 |
Androctonus crassicauda sting and its clinical study in Iran.
Topics: Animals; Antivenins; Atropine; Autonomic Nervous System; Bites and Stings; Central Nervous System; H | 1990 |
Effect of the topical anesthetic EMLA on the efficacy of pulsed dye laser treatment of port-wine stains.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Drug Combin | 1990 |
Electrical stimulation of cervical vagal afferents. II. Central relays for behavioral antinociception and arterial blood pressure decreases.
Topics: Animals; Behavior, Animal; Blood Pressure; Brain Stem; Electric Stimulation; Ibotenic Acid; Lidocain | 1990 |
Multiple angiolipomata treated with intravenous infusions of lignocaine.
Topics: Double-Blind Method; Female; Hemangioma; Humans; Infusions, Intravenous; Lidocaine; Lipoma; Middle A | 1990 |
Abolition of injection pain due to propofol in children.
Topics: Anesthesia, Intravenous; Child; Child, Preschool; Humans; Infant; Lidocaine; Pain; Propofol | 1990 |
Minimizing pain due to local anesthesia.
Topics: Anesthesia, Local; Humans; Injections; Lidocaine; Pain | 1990 |
Pain relief in hysterosalpingography. A comparison of analgesics.
Topics: Analgesics; Benzocaine; Dose-Response Relationship, Drug; Drug Combinations; Female; Gels; Humans; H | 1990 |
Carotid endarterectomy under cervical plexus block--a prospective clinical audit.
Topics: Aged; Carotid Arteries; Cervical Plexus; Constriction; Consumer Behavior; Endarterectomy; Female; Hu | 1990 |
Insufficient effect of local analgesics in Ehlers Danlos type III patients (connective tissue disorder).
Topics: Adult; Anesthetics, Local; Drug Combinations; Ehlers-Danlos Syndrome; Female; Humans; Lidocaine; Lid | 1990 |
Enhancement of local anaesthesia action by organic acid salts. (I): Possible change of excitability in nerve fibre membrane.
Topics: Action Potentials; Animals; Astacoidea; Carboxylic Acids; Humans; Lidocaine; Neural Conduction; Neur | 1987 |
Curettage of molluscum contagiosum in children: analgesia by topical application of a lidocaine/prilocaine cream (EMLA).
Topics: Administration, Cutaneous; Adolescent; Analgesia; Child; Child, Preschool; Curettage; Female; Humans | 1988 |
Failure of epidural opioid to control cancer pain in a patient previously treated with massive doses of intravenous opioid.
Topics: Adenocarcinoma; Bupivacaine; Cecal Neoplasms; Clonidine; Female; Humans; Hydromorphone; Infusions, I | 1989 |
Lignocaine-prilocaine cream in postherpetic neuralgia.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Drug Combinations; Female; Herpes Zoster; Humans | 1989 |
Diagnostic epidural opioid technique.
Topics: Adult; Age Factors; Aged; Analgesia, Epidural; Chronic Disease; Disability Evaluation; Female; Fenta | 1989 |
Distribution of pain provoked from lumbar facet joints and related structures during diagnostic spinal infiltration.
Topics: Back Pain; Humans; Injections, Spinal; Lidocaine; Lumbar Vertebrae; Nerve Block; Pain; Pain Measurem | 1989 |
Mistaken injection of sodium bicarbonate.
Topics: Anesthesia, Local; Bicarbonates; Humans; Injections, Subcutaneous; Lidocaine; Nose; Pain; Sodium; So | 1989 |
Lidocaine treatment of painful diabetic neuropathy and endogenous opioid peptides in plasma.
Topics: Adult; beta-Endorphin; Diabetic Neuropathies; Dynorphins; Endorphins; Female; Humans; Lidocaine; Mal | 1989 |
Analgesia produced by injection of lidocaine into the anterior cingulum bundle of the rat.
Topics: Analgesia; Animals; Gyrus Cinguli; Lidocaine; Male; Pain; Rats | 1989 |
A safer technique for retrobulbar alcohol injections.
Topics: Drug Therapy, Combination; Ethanol; Eye; Humans; Injections; Lidocaine; Pain | 1989 |
Common regional pain syndromes. III.
Topics: Drug Combinations; Foot; Humans; Injections; Knee; Lidocaine; Pain; Pain Management; Steroids; Syndr | 1989 |
Evidence for central phenomena participating in the changes of responses of ventrobasal thalamic neurons in arthritic rats.
Topics: Action Potentials; Animals; Arthritis; Epinephrine; Lidocaine; Male; Pain; Rats; Rats, Inbred Strain | 1989 |
Less painful alcohol block.
Topics: Ethanol; Humans; Lidocaine; Nerve Block; Pain | 1989 |
Diagnosis and treatment of injury to the second and third carpometacarpal joints.
Topics: Adolescent; Adult; Arthrodesis; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Wrist Injuries | 1989 |
Topical lidocaine for relief of superficial pain in postherpetic neuralgia.
Topics: Administration, Topical; Aged; Bandages; Drug Evaluation; Female; Herpes Zoster; Humans; Lidocaine; | 1989 |
The burning truth.
Topics: Adolescent; Adult; Humans; Lidocaine; Pain | 1989 |
Pain on injection of methohexitone. The use of lignocaine to modify pain on injection of methohexitone during anaesthesia for electroconvulsive therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Drug Combinations; Electroconvu | 1989 |
[Peripheral analgesic actions of opioid peptides and morphine analogues].
Topics: Analgesics, Opioid; Animals; Cyclazocine; Dynorphins; Enkephalin, Methionine; Ethylketocyclazocine; | 1986 |
[Effects of nucleus raphe magnus and locus coeruleus in descending modulation of the habenula on pain threshold and acupuncture analgesia].
Topics: Acupuncture Therapy; Analgesia; Animals; Efferent Pathways; Electric Stimulation; Female; Glutamates | 1988 |
[The influence of blocking habenulae or medial forebrain bundles on the analgesic effect elicited by administration L-glutamic acid into the septa].
Topics: Analgesia; Animals; Female; Glutamates; Glutamic Acid; Lidocaine; Male; Medial Forebrain Bundle; Neu | 1988 |
Pain of delayed traumatic splenic rupture masked by intrapleural lidocaine.
Topics: Humans; Lidocaine; Male; Middle Aged; Pain; Pain Management; Pleura; Splenic Rupture | 1989 |
Nursing management of the patient with acute myocardial infarction.
Topics: Angioplasty, Balloon; Coronary Care Units; Early Ambulation; Emergency Medical Services; Fibrinolyti | 1986 |
Sodium bicarbonate attenuates pain on skin infiltration with lidocaine, with or without epinephrine.
Topics: Bicarbonates; Double-Blind Method; Drug Evaluation; Epinephrine; Humans; Hydrogen-Ion Concentration; | 1987 |
Procedures used in the diagnosis of pain.
Topics: Afferent Pathways; Anesthesia, Spinal; Barbiturates; Diagnosis, Differential; Efferent Pathways; Hum | 1986 |
Modifications in the responsiveness of rat ventrobasal thalamic neurons at different stages of carrageenin-produced inflammation.
Topics: Action Potentials; Acute-Phase Reaction; Animals; Aspirin; Carrageenan; Inflammation; Lidocaine; Mal | 1986 |
A characterization of the antinociception produced by intracerebroventricular injection of 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate in mice.
Topics: Analgesia; Anesthetics, Local; Animals; Atropine; Biological Assay; Brain; Calcimycin; Calcium; Dose | 1986 |
Managing the pain of herpes zoster.
Topics: Adult; Aged; Doxepin; Female; Herpes Zoster; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Neur | 1986 |
Steroids and low-back pain.
Topics: Adult; Aged; Back Pain; Epidural Space; Evaluation Studies as Topic; Female; Humans; Injections; Lid | 1985 |
Diagnostic epidural opioid blockade and chronic pain: preliminary report.
Topics: Adult; Aged; Anesthesia, Epidural; Back Pain; Chronic Disease; Diagnosis, Differential; Female; Fent | 1985 |
Spinal recordings suggest that wide-dynamic-range neurons mediate sympathetically maintained pain.
Topics: Adaptation, Physiological; Adrenergic Fibers; Animals; Cats; Electric Stimulation; Female; Lidocaine | 1988 |
[Intravenous anesthesia: effects of the venous puncture].
Topics: Administration, Cutaneous; Anesthesia, Intravenous; Blood Pressure; Female; Humans; Lidocaine; Ointm | 1988 |
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 1st communication: effect on the central nervous system.
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Body Temperature; Catalepsy; Cats; Central Ne | 1988 |
Epidural xylocaine and pethidine for control of labor pain--a comparative study.
Topics: Adult; Analgesia, Epidural; Anesthesia, Obstetrical; Female; Humans; Labor, Obstetric; Lidocaine; Me | 1988 |
Brain-stem relays mediating stimulation-produced antinociception from the lateral hypothalamus in the rat.
Topics: Animals; Brain; Brain Stem; Hot Temperature; Hypothalamus; Ibotenic Acid; Injections; Lidocaine; Mal | 1988 |
Local injection therapy for the treatment of chronic pain.
Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Humans; Injections; Lidocaine; Male; Middle Aged; | 1988 |
Prevention of pain on injection.
Topics: Anesthesia, Intravenous; Humans; Injections, Intravenous; Lidocaine; Pain; Phenols; Propofol | 1988 |
A technique to decrease the pain of lidocaine injection.
Topics: Humans; Injections, Intradermal; Lidocaine; Pain | 1988 |
A prospective blinded trial of warm and cold lidocaine for intradermal injection.
Topics: Anesthesia, Local; Humans; Injections, Intradermal; Lidocaine; Pain; Prospective Studies; Temperatur | 1988 |
pH buffering of local anesthetic solutions: marked reduction in pain with local infiltration of anesthetic solutions.
Topics: Anesthetics, Local; Buffers; Humans; Lidocaine; Pain | 1988 |
Effects of intrathecal fentanyl and lidocaine on somatosensory-evoked potentials, the H-reflex, and clinical responses.
Topics: Electric Stimulation; Evoked Potentials, Somatosensory; Fentanyl; H-Reflex; Humans; Injections, Spin | 1988 |
The lumbar facet syndrome.
Topics: Female; Humans; Injections, Spinal; Lidocaine; Lumbar Vertebrae; Male; Pain; Retrospective Studies; | 1988 |
How to differentiate GI irritation from other causes of chest and upper abdominal pain.
Topics: Abdomen; Antacids; Chest Pain; Gastrointestinal Diseases; Humans; Lidocaine; Pain | 1988 |
[The use of immobilized preparations for the control of suppurative-inflammatory complications and the pain syndrome in trauma and after the operation].
Topics: Adolescent; Adult; Anti-Infective Agents; Child; Dimethylpolysiloxanes; Female; Humans; Lidocaine; M | 1988 |
Local anesthetics potentiate spinal morphine antinociception.
Topics: Anesthesia, Endotracheal; Animals; Bupivacaine; Drug Synergism; Injections, Spinal; Lidocaine; Male; | 1988 |
Analgesia produced by injection of lidocaine into the lateral hypothalamus.
Topics: Animals; Formaldehyde; Hypothalamus; Injections; Lidocaine; Male; Pain; Pain Measurement; Rats | 1987 |
Pain on injection with propofol.
Topics: Anesthetics; Humans; Lidocaine; Pain; Phenols; Propofol | 1986 |
Does heating lidocaine decrease the pain of injection?
Topics: Anesthesia, Local; Humans; Lidocaine; Pain; Temperature | 1987 |
Elimination of pain caused by Small-Carrion penile prosthesis.
Topics: Humans; Lidocaine; Male; Middle Aged; Pain; Penis; Prostheses and Implants | 1987 |
Myalgia and biochemical changes following intermittent suxamethonium administration. Effects of alcuronium, lignocaine, midazolam and suxamethonium pretreatments on serum myoglobin, creatinine kinase and myalgia.
Topics: Adult; Alcuronium; Creatine Kinase; Female; Humans; Lidocaine; Midazolam; Muscular Diseases; Myoglob | 1987 |
Diffuse noxious inhibitory controls of lumbar spinal neurons involve a supraspinal loop in the cat.
Topics: Action Potentials; Animals; Cats; Electric Stimulation; Hot Temperature; Lidocaine; Medulla Oblongat | 1987 |
[Diagnostic and therapeutic blockade of the celiac ganglia].
Topics: Abdomen; Adult; Aged; Celiac Plexus; Ethanol; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Pa | 1987 |
Spinal pathways mediating tonic, coeruleospinal, and raphe-spinal descending inhibition in the rat.
Topics: Animals; Efferent Pathways; Lidocaine; Locus Coeruleus; Male; Neural Inhibition; Norepinephrine; Pai | 1987 |
Comparison of pain associated with intradermal and subcutaneous infiltration with various local anesthetic solutions.
Topics: Anesthetics, Local; Bupivacaine; Etidocaine; Humans; Injections, Intradermal; Injections, Subcutaneo | 1987 |
Use of lidocaine to reduce pain associated with potassium chloride infusions.
Topics: Humans; Infusions, Intravenous; Lidocaine; Pain; Potassium Chloride | 1987 |
Pain-free intravenous injections.
Topics: Humans; Injections, Intravenous; Lidocaine; Pain | 1987 |
Post-traumatic arthrosis of the index carpometacarpal joint. A rationale for treatment and report of two cases.
Topics: Adult; Arthrodesis; Chronic Disease; Female; Humans; Lidocaine; Male; Metacarpus; Methylprednisolone | 1987 |
[Effects of lidocaine, meperidine or fentanyl on pain and clinical thrombophlebitis induced by intravenous diazepam].
Topics: Adult; Diazepam; Female; Fentanyl; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Lido | 1987 |
[Syndrome of perforating lateral branches of the subcostal and ilio-hypogastric nerves. An unrecognized cause of hip pain].
Topics: Arthritis; Diagnosis, Differential; Female; Hip; Hip Joint; Humans; Lidocaine; Lumbosacral Plexus; M | 1986 |
Lidocaine to relieve pain with tissue expansion of the breast.
Topics: Breast; Female; Humans; Lidocaine; Pain; Prostheses and Implants; Surgery, Plastic | 1987 |
Abolishing pain on injection of etomidate.
Topics: Etomidate; Humans; Injections; Lidocaine; Pain | 1987 |
Sedation and pain management during pacemaker implantation, electrophysiologic testing, and related procedures.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Local; Diazepam; Electrophysiology; Female; Humans; | 1985 |
Effect of lignocaine on pain caused by propofol injection.
Topics: Adolescent; Adult; Anesthetics; Female; Humans; Lidocaine; Middle Aged; Pain; Phenols; Propofol | 1985 |
Assessment and modification of pain on induction with propofol (Diprivan).
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics; Apnea; Female; Hemodynamics; Humans; Lidocaine; M | 1985 |
Injecting painful knees with triamcinolone.
Topics: Adult; Aged; Humans; Injections; Knee; Lidocaine; Middle Aged; Pain; Triamcinolone Acetonide | 1985 |
Relief of myocardial ischemia pain with a gastrointestinal cocktail.
Topics: Adult; Aged; Antacids; Diagnosis, Differential; Female; Gastritis; Humans; Lidocaine; Male; Myocardi | 1985 |
Differential spread of blockade of touch, cold, and pinprick during spinal anesthesia.
Topics: Adult; Aged; Anesthesia, Spinal; Cold Temperature; Epinephrine; Female; Humans; Lidocaine; Male; Mid | 1985 |
Cardiopulmonary arrest due to misuse of viscous lidocaine.
Topics: Candidiasis, Oral; Child, Preschool; Female; Heart Arrest; Humans; Lidocaine; Pain | 1985 |
The management of chronic pain syndromes in the upper extremity.
Topics: Analgesia; Arm; Causalgia; Electric Stimulation Therapy; Female; Humans; Lidocaine; Male; Nerve Bloc | 1974 |
Experimental local thalamic application of xylocaine through silicone rubber chemode.
Topics: Analgesia; Animals; Catheterization; Conditioning, Psychological; Electric Stimulation; Haplorhini; | 1973 |
[Combined drug therapy in highly acute attacks of pain in the course of rheumatic diseases].
Topics: Acute Disease; Aminopyrine; Arthritis, Rheumatoid; Dexamethasone; Drug Combinations; Female; Humans; | 1974 |
Anesthesia for diagnostic and operative laparoscopy.
Topics: Abdomen; Adolescent; Adult; Analgesia; Anesthesia; Anesthesia, General; Anesthesia, Local; Diazepam; | 1971 |
Laparoscopic tubal clip sterilization under local anesthesia.
Topics: Adult; Anesthesia, Local; Diazepam; Drug Evaluation; Fallopian Tubes; Female; Fentanyl; Humans; Lapa | 1974 |
Abdominal cutaneous nerve entrapment syndrome.
Topics: Abdomen; Adult; Aged; Diagnosis, Differential; Female; Humans; Lidocaine; Male; Nerve Compression Sy | 1972 |
Meralgia paresthetica.
Topics: Femoral Nerve; Humans; Inguinal Canal; Lidocaine; Pain; Paresthesia; Peripheral Nervous System Disea | 1972 |
[Thoracic pains. Rhomboideus "pedicle" syndrome].
Topics: Humans; Injections; Lidocaine; Muscular Diseases; Pain; Shoulder; Spine; Tendons; Thoracic Vertebrae | 1973 |
Head and neck pain: T-M joint syndrome.
Topics: Adult; Age Factors; Aged; Diagnosis, Differential; Diazepam; Female; Head; Humans; Lidocaine; Male; | 1974 |
Prolonged regional analgesia in scleroderma.
Topics: Amputation, Surgical; Analgesia; Bicarbonates; Dextrans; Female; Fingers; Humans; Hydrogen-Ion Conce | 1974 |
Relief of pain in labor.
Topics: Analgesics; Anesthesia, Conduction; Anesthesia, Inhalation; Anesthesia, Obstetrical; Cervix Uteri; F | 1974 |
The arousal and suppression of pain in the tooth.
Topics: Action Potentials; Animals; Cats; Dental Pulp; Dentin; Dogs; Electric Stimulation; Hot Temperature; | 1972 |
Respiratory changes during continuous epidural blockade.
Topics: Acid-Base Equilibrium; Adult; Anesthesia, Epidural; Cardiac Output; Cholecystectomy; Female; Humans; | 1972 |
Blood concentration of lidocaine during continuous epidural blockade.
Topics: Adult; Anesthesia, Epidural; Cholecystectomy; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Ti | 1972 |
Circulatory changes during continuous epidural blockade.
Topics: Adult; Anesthesia, Epidural; Blood Pressure; Body Temperature; Cardiac Output; Cholecystectomy; Fema | 1972 |
[Thoracic epidural analgesia. A review of the use of continuous epidural analgesia in connection with upper abdominal operations].
Topics: Abdomen; Adolescent; Adult; Age Factors; Aged; Anesthesia, Epidural; Blood Circulation; Catheterizat | 1972 |
Perceptual changes accompanying controlled preferential blocking of A and C fibre responses in intact human skin nerves.
Topics: Adult; Electric Stimulation; Humans; Lidocaine; Male; Microelectrodes; Nerve Fibers, Myelinated; Neu | 1973 |
Anesthesia in obstetrics. 2. Regional.
Topics: Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Cervix Ut | 1973 |
[Prolonged postoperative peridural analgesia].
Topics: Adolescent; Adult; Aged; Analgesia; Humans; Lidocaine; Methods; Middle Aged; Pain; Postoperative Com | 1973 |
Effect of sacral nerve blocks on the function of the urinary bladder in humans.
Topics: Diabetes Mellitus; Humans; Lidocaine; Lumbosacral Plexus; Multiple Sclerosis; Nerve Block; Pain; Par | 1974 |
Spinal and extradural analgesia-anesthesia for parturition.
Topics: Analgesia; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bu | 1974 |
Paracervical block: advantages and disadvantages.
Topics: Acidosis; Anesthesia, Obstetrical; Anesthetics, Local; Bradycardia; Cervix Uteri; Female; Fetal Dise | 1974 |
Regional nerve block with the aid of a nerve stimulator.
Topics: Anesthesia, Conduction; Bupivacaine; Electric Stimulation; Humans; Lidocaine; Methods; Muscle Contra | 1972 |
Iatrogenic pneumothorax. A report of three cases.
Topics: Adult; Aged; Back; Female; Humans; Iatrogenic Disease; Injections, Intramuscular; Lidocaine; Muscles | 1972 |
Closed hemorrhoidectomy with local anesthesia.
Topics: Abscess; Anesthesia, Local; Hemorrhage; Hemorrhoids; Humans; Injections, Subcutaneous; Lidocaine; Me | 1972 |
Post-tonsillectomy morbidity: a clinical trial of a local penicillin-steroid-anesthetic mixture.
Topics: Child, Preschool; Feeding and Eating Disorders; Hemorrhage; Humans; Lidocaine; Methylprednisolone; P | 1967 |
Propulsive gastrointestinal motility related to retroperitoneal irritation. An experimental study in the rat.
Topics: Anesthesia, Local; Animals; Autonomic Nerve Block; Blood; Chromium Isotopes; Digestive System; Gastr | 1968 |
Factors influencing the response of lesions of the rotator cuff of the shoulder to local steroid injection.
Topics: Adrenal Cortex Hormones; Adult; Aged; Blood Sedimentation; Cervical Vertebrae; Female; Humans; Injec | 1969 |
Central nervous system responses to tooth pulp stimulation and their modification by drugs.
Topics: Anesthetics; Animals; Brain; Brain Stem; Cerebral Cortex; Dental Pulp; Dogs; Evoked Potentials; Lido | 1970 |
[Local analgesics in tooth treatment--mode of operation and area of use].
Topics: Anesthesia, Dental; Anesthetics, Local; Dental Pulp Diseases; Drug Synergism; Epinephrine; Felypress | 1971 |
The use of epidural block in acute pancreatitis: a report of eight cases.
Topics: Acute Disease; Adult; Aged; Anesthesia, Spinal; Electrocardiography; Electrolytes; Female; Humans; L | 1969 |
The relief of pain in labour by means of continuous-drip epidural block.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Female; Humans; Labor, Obstetric; Lidocaine; Methods; P | 1969 |
[Experiences with a new anesthesia--spray technic in obstetrics].
Topics: Aerosols; Anesthesia, Obstetrical; Female; Humans; Labor, Obstetric; Lidocaine; Methods; Pain; Pregn | 1969 |
[Our experience in antalgic therapy of peripheral arteriopathies].
Topics: Arteriosclerosis; Diabetic Angiopathies; Humans; Lidocaine; Pain; Raynaud Disease; Thromboangiitis O | 1971 |
[Serum concentrations and painful reactions following injection of benzyl penicillin dissolved in sterile water and in lidocaine solution].
Topics: Humans; Injections, Intramuscular; Lidocaine; Pain; Penicillin G; Solutions; Time Factors; Water | 1971 |
[Postoperative pain control].
Topics: Abdomen; Adolescent; Adult; Aged; Anesthesia, Conduction; Anesthetics, Local; Female; Humans; Laparo | 1967 |
[On hypalgesia in the postoperative period with patients operated on in the ano-rectal region, determined by intravenous lidocaine. Clinical results].
Topics: Anus Diseases; Female; Humans; Lidocaine; Male; Pain; Postoperative Care; Rectal Diseases | 1967 |
[Lac-43 in extradural spinal block in surgery. Postoperative pain control].
Topics: Adolescent; Adult; Aged; Anesthesia, Spinal; Anilides; Child; Humans; Lidocaine; Mepivacaine; Method | 1968 |
Shoulder pain. Suprascapular nerve block in shoulder pain.
Topics: Autonomic Nerve Block; Humans; Lidocaine; Pain; Phenols; Shoulder | 1969 |
The management of chronic interstitial cystitis by differential sacral neurotomy.
Topics: Adult; Aged; Cystitis; Cystoscopy; Female; Humans; Lidocaine; Lumbosacral Plexus; Pain; Procaine; Ur | 1969 |
Osteoarthritis of the carpometacarpal joint of the thumb.
Topics: Anti-Inflammatory Agents; Arthrodesis; Arthroplasty; Female; Humans; Injections, Intra-Articular; Li | 1969 |
Continuous epidural analgesia for labour and delivery: review of 1000 cases.
Topics: Anesthesia, Obstetrical; Epinephrine; Female; Humans; Lidocaine; Mepivacaine; Pain; Pregnancy | 1966 |
Anti-rabies vaccine employing a dental anesthetic as the vehicle: pilot study.
Topics: Anesthesia, Local; Animals; Humans; Lidocaine; Male; Mice; Pain; Pharmaceutical Vehicles; Rabies Vac | 1966 |
[Lemaire's phenomenon in the pathognomy and therapy of gynaecological syndromes].
Topics: Adult; Anesthesia, Local; Female; Humans; Lidocaine; Middle Aged; Pain; Pregnancy | 1966 |