Page last updated: 2024-10-28

lidocaine and Abscess

lidocaine has been researched along with Abscess in 22 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Abscess: Accumulation of purulent material in tissues, organs, or circumscribed spaces, usually associated with signs of infection.

Research Excerpts

ExcerptRelevanceReference
"We tested the following hypothesis: The addition of intranasal fentanyl to the standard practice of local infiltration with lidocaine would provide better pain control than lidocaine alone for adult ED patients undergoing I&D."9.51A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess. ( Baer, J; Feliciano, C; Friedman, BW; Gupta, C; Latev, A; Sharpe, S, 2022)
"We studied the analgesia provided by a lidocaine/tetracaine patch compared to injectable lidocaine during incision and drainage (I&D) of skin abscesses."9.19Injectable lidocaine provides similar analgesia compared to transdermal lidocaine/tetracaine patch for the incision and drainage of skin abscesses: a randomized, controlled trial. ( Bourne, CL; Brewer, KL; House, J, 2014)
"We tested the following hypothesis: The addition of intranasal fentanyl to the standard practice of local infiltration with lidocaine would provide better pain control than lidocaine alone for adult ED patients undergoing I&D."5.51A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess. ( Baer, J; Feliciano, C; Friedman, BW; Gupta, C; Latev, A; Sharpe, S, 2022)
"We studied the analgesia provided by a lidocaine/tetracaine patch compared to injectable lidocaine during incision and drainage (I&D) of skin abscesses."5.19Injectable lidocaine provides similar analgesia compared to transdermal lidocaine/tetracaine patch for the incision and drainage of skin abscesses: a randomized, controlled trial. ( Bourne, CL; Brewer, KL; House, J, 2014)
"We report a rare case of hypersensitivity in a 63-year-old man who received subconjunctival lidocaine, cefazolin, and gentamicin for corneal abscess."3.73Lidocaine hypersensitivity after subconjunctival injection. ( Levy, J; Lifshitz, T, 2006)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19906 (27.27)18.7374
1990's4 (18.18)18.2507
2000's6 (27.27)29.6817
2010's5 (22.73)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Latev, A1
Baer, J1
Sharpe, S1
Gupta, C1
Feliciano, C1
Friedman, BW1
Elkoundi, A1
Bensghir, M1
Lalaoui, SJ1
Bourne, CL1
Brewer, KL1
House, J1
Rish, A1
Boulos, PR1
Rubin, PA1
Rousso, JJ1
Pitman, MJ1
Iida, T1
Suzuki, A1
Kunisawa, T1
Iwasaki, H1
Levy, J1
Lifshitz, T1
Dojcinovic, I1
Hugentobler, M1
Richter, M1
Hoelzer, BC1
Weingarten, TN1
Hooten, WM1
Wright, RS1
Wilson, WR1
Wilson, PR1
Takahashi, Y1
Köle, W1
Ohlmann, D1
Treib, J1
Hamann, GF1
Hermes, M1
Schimrigk, K1
Rodríguez, G1
Ortegón, M1
Camargo, D1
Orozco, LC1
Simon, E1
Matee, M1
Munshi, AK1
Hegde, AM1
Latha, R1
Lichtman, DM1
Swafford, AW1
Kerr, DM1
Kratzer, GL1
Lazorthes, F1
Chiotasso, P1
Massip, P1
Materre, JP1
Sarkissian, M1
Dixon, JM1
Khubchandani, IT1
Trimpi, HD1
Sheets, JA1
Khafif, RA1
Attie, JN1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Trial of Intranasal Fentanyl Versus Placebo as an Adjunct to Lidocaine Infiltration in Adults Undergoing Abscess Incision and Drainage in the Emergency[NCT03872700]Phase 349 participants (Actual)Interventional2019-08-01Completed
A Study of the Role of Some Drug Delivery Systems in Enhancing the Efficiency of EMLA Cream in Palatal Anesthesia for Children Aged Between 7-11 Years Old[NCT05187494]75 participants (Actual)Interventional2021-05-20Completed
Study Protocol for A Randomized Controlled Trial of Incision and Drainage Versus Ultrasound-Guided Needle Aspiration for Uncomplicated Skin Abscesses[NCT04127071]40 participants (Anticipated)Interventional2020-06-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

NRS Pain Score After Blunt Dissection

Patient reported NRS pain scores after Blunt Dissection. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl4.1
Placebo4.4

NRS Pain Score After Irrigation

Patient reported NRS pain scores after Irrigation. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl3.4
Placebo2.6

NRS Pain Score After Lidocaine Injection

Patient reported NRS pain scores after Lidocaine injection. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Following Lidocaine injection measured once anytime up to 12 minutes after intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl8.4
Placebo8.0

NRS Pain Score After Packing of Abscess

Patient reported pain after Packing of abscess. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once at the time of completion of application of the bandage, up to 60 minutes following intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl4.5
Placebo3.9

NRS Pain Score Following Incision

Patient reported NRS pain scores following Incision. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl3.9
Placebo3.9

Numerical Rating Scale (NRS) Pain Score at Baseline

Patient reported pain scores at baseline. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Baseline

Interventionscore on a scale (Mean)
Intranasal Fentanyl8.3
Placebo8.1

Numerical Rating Scale (NRS) Pain Score for Overall Procedure

Patient reported pain scores for overall Procedure assessed immediately after placement of dressing at the end of procedure. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once following placement of dressing at completion of procedure, up to 60 minutes following intranasal administration

Interventionscore on a scale (Mean)
Intranasal Fentanyl6.2
Placebo7.0

Trials

3 trials available for lidocaine and Abscess

ArticleYear
A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess.
    The Journal of emergency medicine, 2022, Volume: 62, Issue:3

    Topics: Abscess; Administration, Intranasal; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Dra

2022
Injectable lidocaine provides similar analgesia compared to transdermal lidocaine/tetracaine patch for the incision and drainage of skin abscesses: a randomized, controlled trial.
    The Journal of emergency medicine, 2014, Volume: 47, Issue:3

    Topics: Abscess; Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Female; Huma

2014
Local antibiotic prophylaxis in inguinal hernia repair.
    Surgery, gynecology & obstetrics, 1992, Volume: 175, Issue:6

    Topics: Abscess; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Cefamandole; Child; Co

1992

Other Studies

19 other studies available for lidocaine and Abscess

ArticleYear
Nebulized ketamine for successful management of difficult airway.
    Journal of clinical anesthesia, 2017, Volume: 41

    Topics: Abscess; Administration, Inhalation; Adult; Aerosols; Anti-Infective Agents; Bronchoscopes; C-Reacti

2017
Polyacrylamide gel 10 years experience: with particular reference to complications from filling of the body of the lip.
    Journal of cosmetic dermatology, 2014, Volume: 13, Issue:4

    Topics: Abscess; Acrylic Resins; Adult; Anesthetics, Local; Anti-Bacterial Agents; Cosmetic Techniques; Gels

2014
A lacrimal sac abscess incision and drainage technique.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2008, Volume: 126, Issue:9

    Topics: Abscess; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics,

2008
Enterococcus faecalis complicating dermal filler injection: a case of virulent facial abscesses.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2010, Volume: 36, Issue:10

    Topics: Abscess; Adult; Enterococcus faecalis; Female; Gram-Positive Bacterial Infections; Humans; Hyaluroni

2010
Ultrasound-guided superior laryngeal nerve block and translaryngeal block for awake tracheal intubation in a patient with laryngeal abscess.
    Journal of anesthesia, 2013, Volume: 27, Issue:2

    Topics: Abscess; Airway Management; Anesthetics, Local; Drainage; Female; Humans; Intubation, Intratracheal;

2013
Lidocaine hypersensitivity after subconjunctival injection.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2006, Volume: 41, Issue:2

    Topics: Abscess; Anesthetics, Local; Conjunctiva; Corneal Diseases; Drug Hypersensitivity; Humans; Injection

2006
[Infracondylar abscess formation: a rare complication of local anesthesia].
    Revue de stomatologie et de chirurgie maxillo-faciale, 2006, Volume: 107, Issue:5

    Topics: Abscess; Adult; Anesthesia, Dental; Anesthetics, Local; Humans; Injections; Lidocaine; Male; Mandibu

2006
Paraspinal abscess complicated by endocarditis following a facet joint injection.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Abscess; Aged; Analgesia, Epidural; Analgesics, Non-Narcotic; Bacteremia; Bupivacaine; Endocarditis,

2008
[The effect of lidocaine hydrochloride on Staphylococcus aureus].
    Gifu Shika Gakkai zasshi = The Journal of Gifu Dental Society, 1983, Volume: 11, Issue:1

    Topics: Abscess; Animals; Escherichia coli; Lidocaine; Male; Mice; Microbial Sensitivity Tests; Rabbits; Sta

1983
[Emergency interventions in anorectal processes].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1982, Volume: 53, Issue:6

    Topics: Abscess; Dermoid Cyst; Emergencies; Foreign Bodies; Hemorrhoids; Humans; Lidocaine; Pilonidal Sinus;

1982
[Paravertebral abscess with secondary meningomyelitis after infiltration therapy. A brief case report].
    Wiener klinische Wochenschrift, 1996, Volume: 108, Issue:14

    Topics: Abscess; Aged; Analgesia, Epidural; Anesthetics, Local; Female; Humans; Lidocaine; Low Back Pain; Ma

1996
Iatrogenic Mycobacterium abscessus infection: histopathology of 71 patients.
    The British journal of dermatology, 1997, Volume: 137, Issue:2

    Topics: Abscess; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Child; Child, Preschool; Co

1997
Post-extraction complications seen at a referral dental clinic in Dar Es Salaam, Tanzania.
    International dental journal, 2001, Volume: 51, Issue:4

    Topics: Abscess; Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthetics, Local;

2001
Use of EMLA: is it an injection free alternative?
    The Journal of clinical pediatric dentistry, 2001,Spring, Volume: 25, Issue:3

    Topics: Abscess; Adolescent; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Child; Child, Pr

2001
Calcified abscess in the ulnar nerve in a patient with leprosy. A case report.
    The Journal of bone and joint surgery. American volume, 1979, Volume: 61, Issue:4

    Topics: Abscess; Adult; Calcinosis; Dapsone; Drainage; Follow-Up Studies; Humans; Leprosy; Lidocaine; Male;

1979
Outpatient anorectal surgery.
    American family physician, 1975, Volume: 11, Issue:3

    Topics: Abscess; Ambulatory Care; Anal Canal; Anesthesia, Local; Anus Diseases; Bandages; Cathartics; Coloni

1975
Outpatient treatment of non-lactational breast abscesses.
    The British journal of surgery, 1992, Volume: 79, Issue:1

    Topics: Abscess; Adult; Ambulatory Care; Anesthetics, Local; Breast Diseases; Drainage; Drug Combinations; F

1992
Closed hemorrhoidectomy with local anesthesia.
    Surgery, gynecology & obstetrics, 1972, Volume: 135, Issue:6

    Topics: Abscess; Anesthesia, Local; Hemorrhage; Hemorrhoids; Humans; Injections, Subcutaneous; Lidocaine; Me

1972
One-stage excision of infected sebaceous cysts.
    Archives of surgery (Chicago, Ill. : 1960), 1969, Volume: 98, Issue:1

    Topics: Abscess; Anesthesia, Local; Epidermal Cyst; Humans; Lidocaine; Methods

1969