lidocaine has been researched along with Abnormal Deep Tendon Reflex in 21 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Furthermore, autonomic hyperreflexia is completely established within 24 h after CST in the rat." | 1.28 | Chronic cervical spinal cord injury and autonomic hyperreflexia in rats. ( Osborn, JW; Schramm, LP; Taylor, RF, 1990) |
| "Prostatic block eliminated hyperreflexia in 10 of 11 patients and had no effect in 4 patients with a normal cystometrogram." | 1.26 | The etiology of detrusor hyperreflexia in patients with infravesical obstruction. ( Bradley, WE; Chalfin, SA, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (47.62) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sullivan, RW | 1 |
| Ryzewski, M | 1 |
| Holland, MG | 1 |
| Marraffa, JM | 1 |
| Takeda, M | 1 |
| Oshima, K | 1 |
| Takahashi, M | 1 |
| Matsumoto, S | 1 |
| Sugitani, K | 1 |
| Shime, N | 1 |
| Hayashi, K | 1 |
| Kakihara, K | 1 |
| Ukimura, O | 1 |
| Tanaka, Y | 1 |
| EADE, MN | 1 |
| Kapur, E | 1 |
| Vuckovic, I | 1 |
| Dilberovic, F | 1 |
| Zaciragic, A | 1 |
| Cosovic, E | 1 |
| Divanovic, KA | 1 |
| Mornjakovic, Z | 1 |
| Babic, M | 1 |
| Borgeat, A | 1 |
| Thys, DM | 1 |
| Hadzic, A | 1 |
| Varela, C | 1 |
| Palacio, F | 1 |
| Reina, MA | 1 |
| López, A | 1 |
| Benito-León, J | 1 |
| Kuhnert, BR | 1 |
| Harrison, MJ | 1 |
| Linn, PL | 1 |
| Kuhnert, PM | 1 |
| Chalfin, SA | 1 |
| Bradley, WE | 1 |
| Vogt, A | 1 |
| dal Ri, H | 1 |
| Schmidt, G | 1 |
| Kreuzer, H | 1 |
| Peterson, T | 1 |
| Mathias, CJ | 1 |
| Alam, M | 1 |
| Chandiramani, V | 1 |
| Fowler, CJ | 2 |
| Dasgupta, P | 1 |
| Stephen, RL | 1 |
| Petersen, T | 1 |
| Nielsen, JB | 1 |
| Schrøder, HD | 1 |
| Jung, SY | 1 |
| Fraser, MO | 1 |
| Ozawa, H | 1 |
| Yokoyama, O | 1 |
| Yoshiyama, M | 1 |
| De Groat, WC | 1 |
| Chancellor, MB | 1 |
| Levo, H | 1 |
| Blomstedt, G | 1 |
| Pyykkö, I | 1 |
| Bódis, L | 1 |
| Radnai, B | 1 |
| Vigreux, G | 1 |
| Vacant, J | 1 |
| Lepresle, E | 1 |
| Desalle De Hys, C | 1 |
| Debras, C | 1 |
| Manfredi, M | 1 |
| Sacco, G | 1 |
| Sideri, G | 1 |
| Osborn, JW | 1 |
| Taylor, RF | 1 |
| Schramm, LP | 1 |
| Mantia, AM | 1 |
| Phillips, OC | 1 |
| de Morsier, G | 1 |
| Sapru, RP | 1 |
| Griffiths, PH | 1 |
| Guz, A | 1 |
| Eisele, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444] | Phase 2 | 13 participants (Actual) | Interventional | 2017-05-23 | Terminated (stopped due to Efficacy was not seen after interim analysis) | ||
| AMPLIFY: Amplifying Sensation in Underactive Bladder[NCT04516434] | 20 participants (Anticipated) | Interventional | 2021-09-01 | Recruiting | |||
| Potential Biomarkers in the Study of Overactive Bladder in Women[NCT03516292] | 108 participants (Anticipated) | Observational | 2018-01-29 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes
| Intervention | Intensity score (Mean) |
|---|---|
| Topical KeAmLi Combo | 62.7 |
| Topical Ketamine | 63.1 |
| Topical Amitriptyline | 69.2 |
| Topical Lidocaine | 65.8 |
| Topical Vehicle | 61.9 |
Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes
| Intervention | mN (Mean) | |
|---|---|---|
| Mechanical Detection Threshold | Mechanical Pain Threshold | |
| Topical Amitriptyline | 3.573423965 | 152.4768146 |
| Topical KeAmLi Combo | 3.519376956 | 152.3293608 |
| Topical Ketamine | 3.464204768 | 135.9 |
| Topical Lidocaine | 3.546037659 | 126.9 |
| Topical Vehicle | 3.525692637 | 148.7138273 |
Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes
| Intervention | Degrees celsius (Mean) | |
|---|---|---|
| Warm Detection Threshold | Heat Pain Threshold | |
| Topical Amitriptyline | 33.9 | 40.0 |
| Topical KeAmLi Combo | 33.6 | 39.8 |
| Topical Ketamine | 34.0 | 40.0 |
| Topical Lidocaine | 33.7 | 39.4 |
| Topical Vehicle | 33.8 | 39.7 |
1 trial available for lidocaine and Abnormal Deep Tendon Reflex
| Article | Year |
|---|---|
Intravesical capsaicin in patients with detrusor hyper-reflexia--a placebo-controlled cross-over study.
Topics: Administration, Intravesical; Anesthetics, Local; Capsaicin; Cross-Over Studies; Female; Humans; Lid | 1999 |
20 other studies available for lidocaine and Abnormal Deep Tendon Reflex
| Article | Year |
|---|---|
Compounded ointment results in severe toxicity in a pediatric patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined M | 2013 |
Systemic administration of lidocaine suppresses the excitability of rat cervical dorsal horn neurons and tooth-pulp-evoked jaw-opening reflex.
Topics: Action Potentials; Anesthetics, Local; Animals; Dental Pulp; Dose-Response Relationship, Drug; Elect | 2009 |
Autonomic hyperreflexia during intravesical administration of resiniferatoxin.
Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Diterpenes; Humans; Lidocaine; Male; Reflex, Abnorm | 2003 |
PAROXYSMAL HYPERTENSION IN SPINAL CORD INJURIES (AUTONOMIC HYPERREFLEXIA).
Topics: Adolescent; Autonomic Dysreflexia; Autonomic Nervous System Diseases; Blushing; Bradycardia; Headach | 1964 |
Neurologic and histologic outcome after intraneural injections of lidocaine in canine sciatic nerves.
Topics: Anesthetics, Local; Animals; Dogs; Injections; Lidocaine; Medical Errors; Nerve Block; Pain Measurem | 2007 |
[Horner's syndrome secondary to epidural anesthesia].
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Arm; Bupivacaine; Cesarean | 2007 |
Effects of maternal epidural anesthesia on neonatal behavior.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Child Behavior; Female; Fetal Blo | 1984 |
The etiology of detrusor hyperreflexia in patients with infravesical obstruction.
Topics: Aged; Humans; Lidocaine; Male; Middle Aged; Prostate; Reflex, Abnormal; Sensation; Urinary Bladder; | 1982 |
Depressive cardiac reflex elicited by angiographic contrast medium and its inhibition by lidocaine.
Topics: Animals; Blood Pressure; Cats; Contrast Media; Coronary Angiography; Diatrizoate; Heart Diseases; He | 1980 |
Simultaneous arterial and urinary bladder pressure recordings in multiple system atrophy and in spinal disorders with detrusor hyperreflexia.
Topics: Adult; Aged; Anesthetics, Local; Blood Pressure; Cold Temperature; Female; Humans; Lidocaine; Male; | 1997 |
Electromotive drug administration of lidocaine to anesthetize the bladder before intravesical capsaicin.
Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Capsaicin; Female; Humans; Iontophore | 1998 |
Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability.
Topics: Anesthetics, Local; Animals; Capsaicin; Enzyme Inhibitors; Female; Lidocaine; Muscle Contraction; Mu | 1999 |
Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability.
Topics: Anesthetics, Local; Animals; Capsaicin; Enzyme Inhibitors; Female; Lidocaine; Muscle Contraction; Mu | 1999 |
Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability.
Topics: Anesthetics, Local; Animals; Capsaicin; Enzyme Inhibitors; Female; Lidocaine; Muscle Contraction; Mu | 1999 |
Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability.
Topics: Anesthetics, Local; Animals; Capsaicin; Enzyme Inhibitors; Female; Lidocaine; Muscle Contraction; Mu | 1999 |
Vestibular schwannoma surgery and headache.
Topics: Adult; Aged; Anesthetics, Local; Dizziness; Female; Follow-Up Studies; Headache; Humans; Lidocaine; | 2000 |
Clinical aspects of carotid sinus hyperaesthesia.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Carotid Sinus; Digoxin; Electrocardiography; Female; | 1979 |
[Post-operative course in tetraplegics after urological surgers (author's transl)].
Topics: Anesthesia, Epidural; Cerebral Hemorrhage; Endoscopy; Gastrointestinal Motility; Humans; Hypertensio | 1976 |
The tonic ambulatory foot response. A clinical and electromyographic study.
Topics: Cerebrovascular Disorders; Electromyography; Female; Foot; Humans; Lidocaine; Locomotion; Male; Midd | 1975 |
Chronic cervical spinal cord injury and autonomic hyperreflexia in rats.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Chronic Disease; Decerebrate State; Injections; L | 1990 |
Lidocaine skinwheal fails to prevent vasovagal reflex during venipuncture.
Topics: Anesthesia, Local; Bradycardia; Humans; Hypotension; Lidocaine; Male; Middle Aged; Punctures; Reflex | 1987 |
[Traumatic intervertebral disk disorders. A study of 31 new cases].
Topics: Adult; Back Pain; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lidocaine; | 1971 |
Syncope on swallowing.
Topics: Adult; Atropine; Deglutition; Electrocardiography; Female; Heart Block; Humans; Lidocaine; Reflex, A | 1971 |