Page last updated: 2024-10-28

lidocaine and Abdominal Migraine

lidocaine has been researched along with Abdominal Migraine in 65 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Four-weekly greater occipital nerve blockade with 2% lidocaine for 12 weeks was superior to placebo in decreasing the average number of headache and migraine days in patients with chronic migraine with a good tolerability profile."5.69Greater occipital nerve blockade for the preventive treatment of chronic migraine: A randomized double-blind placebo-controlled study. ( Chowdhury, D; Deorari, V; Duggal, A; Koul, A; Krishnan, A; Tomar, A, 2023)
"This study showed that GONB with lidocaine can improve sleep quality, insomnia, and symptoms of depression and anxiety while reducing migraine headache."4.31The effects of greater occipital nerve blockage with lidocaine on sleep characteristics in chronic migraine patients. ( Dilek, SS; İnan, LE; Karaduman, Y; Metin, KM; Serçe, A; Takmaz, SA, 2023)
"A hundred patients with migraine attacks, aged between 18 and 65, were randomly divided into two groups."3.11Intravenous lidocaine vs. NSAIDs for migraine attack in the ED: a prospective, randomized, double-blind study. ( Ahiskalioglu, A; Ahiskalioglu, EO; Aydin, ME; Aydin, P; Gur, STA; Kocak, AO, 2022)
"Status migrainosus is a disabling complication of migraine, which frequently results in hospitalisation."3.11Status migrainosus inpatient treatment with eptinezumab (SMITE): study protocol for a randomised controlled trial. ( Chen, Z; Germaine, J; Hutton, EJ; Ramsay, G; Ray, JC, 2022)
"Eighty-seven patients diagnosed with migraine without aura were included in the study."2.90Greater occipital and supraorbital nerve blockade for the preventive treatment of migraine: a single-blind, randomized, placebo-controlled study. ( Altun, D; Bölük, C; Köseoğlu Toksoy, C; Özer, D; Taşdemir, M; Türk Börü, Ü, 2019)
"Migraine affects more than 35 million people in the United States of America, and 10% of the population in the world."2.87Effectiveness of surgical treatment in chronic migraine. ( Amaya-Blas, FJ; Castro-Góvea, Y; Chacón-Moreno, H; Coutiño, R; García-Pérez, MM; Marfil-Rivera, A; Mecott, GA; Pérez-Porras, S; Tamayo-Esquivel, ML, 2018)
"Included patients met the migraine criteria of the International Headache Society."2.84Intranasal Lidocaine in Acute Treatment of Migraine: A Randomized Controlled Trial. ( Akalın, LE; Alyeşil, C; Avcu, N; Doğan, NÖ; Pekdemir, M; Yaka, E; Yılmaz, S, 2017)
" The most frequently reported adverse events in both groups were associated with nasal discomfort."2.77Intranasal ketorolac tromethamine (SPRIX(R)) containing 6% of lidocaine (ROX-828) for acute treatment of migraine: safety and efficacy data from a phase II clinical trial. ( Bregman, D; Färkkila, M; Fenzl, E; Pfaffenrath, V, 2012)
"Many patients with refractory chronic migraine have experienced treatment failure with the Raskin protocol."2.72Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine. ( Lauritsen, C; Mojica, JJ; Nahas, SJ; Schwenk, ES, 2021)
"Subjects scored the intensity of headache and nausea on separate visual analogue scales before the injection and at 10 and 20 min after injection."2.67Is intravenous lidocaine clinically effective in acute migraine? ( Fatovich, DM; Prentice, DA; Reutens, DC; Stewart-Wynne, EG, 1991)
"Pediatric migraine is a common, chronic, and disabling neurological disorder in children and adolescents."2.66Intravenous Migraine Treatment in Children and Adolescents. ( Hershey, AD; Kabbouche, M; Maconochie, I; Murphy, B; Qaiser, S; Werner, K, 2020)
"While 21 out of 39 episodic migraine (EM) patients continued to use prophylactic medications, 18 were followed up with PNB alone."1.91Evaluation of the efficacy of peripheral nerve block alone in episodic and chronic migraine patients. ( Evcili, G; Yabalak, A, 2023)
"Patients with refractory chronic migraine have poor quality of life."1.72Lidocaine infusions for refractory chronic migraine: a retrospective analysis. ( Lauritsen, CG; Mukhtar, S; Nardone, B; Patel, HT; Schwenk, ES; Silberstein, SD; Sun, G; Thota, B; Torjman, MC; Walter, A, 2022)
"Patients with refractory chronic migraine have substantial disability and have failed many acute and preventive medications."1.62Ketamine for Refractory Chronic Migraine: An Observational Pilot Study and Metabolite Analysis. ( Denk, W; Katz, D; Lauritsen, C; Lovett, J; Moaddel, R; Schwenk, ES; Silberstein, SD; Torjman, MC; Wainer, IW, 2021)
"In two patients with status migrainosus, migraine-related disability 3 months prior and after treatment using MIDAS (Migraine Disability Assessment) questionnaire was recorded."1.62Intra-arterial injection of lidocaine into middle meningeal artery to treat intractable headaches and severe migraine. ( Babar, S; French, BR; Gomez, CR; Huang, W; Ishfaq, MF; Lobanova, I; Pfeiffer, K; Qureshi, AI; Siddiq, F, 2021)
"The outcomes observed were migraine pain before and after administration within the same initial encounter of receiving an occipital nerve block using a numeric pain rating scale, injection direction, medications used, duration of effect and frequency of additional injections, and adverse reactions."1.56Evaluation of Occipital Nerve Blocks for Acute Pain Relief of Migraines. ( Dang, T; Ebied, AM; Nguyen, DT, 2020)
"Although migraine is one of the most common primary headaches, its therapy is still limited in many cases."1.56Trigeminal activation patterns evoked by chemical stimulation of the dura mater in rats. ( Bohár, Z; Fejes-Szabó, A; Laborc, KF; Nagy-Grócz, G; Párdutz, Á; Spekker, E; Szűcs, M; Vécsei, L, 2020)
"A sudden loss of consciousness and tonic-clonic seizure was occurred after negative aspiration and test dose."1.51Tonic-clonic seizure during the ultrasound-guided stellate ganglion block because of an injection into an unrecognized variant vertebral artery: A case report. ( Dong, J; Lu, F; Tian, J; Zhang, K, 2019)
"Lidocaine was administered as a bolus (2."1.48Safety and Efficacy of IV Lidocaine in the Treatment of Children and Adolescents With Status Migraine. ( Ayulo, MA; Phillips, KE; Tripathi, S, 2018)
"Therapeutic management of Chronic Migraine (CM), often associated with Medication Overuse Headache (MOH), is chiefly empirical, as no biomarker predicting or correlating with clinical efficacy is available to address therapeutic choices."1.48Neurophysiological correlates of clinical improvement after greater occipital nerve (GON) block in chronic migraine: relevance for chronic migraine pathophysiology. ( Altieri, M; Di Piero, V; Petolicchio, B; Puledda, F; Ruggiero, S; Sasso D'Elia, T; Schoenen, J; Torrieri, MC; Toscano, M; Verzina, A; Vicenzini, E; Viganò, A, 2018)
"Thus the pain of migraine may not always be the result of peripheral sensory stimulation, but may also arise by a central mechanism."1.37Effect of cortical spreading depression on basal and evoked traffic in the trigeminovascular sensory system. ( Lambert, GA; Truong, L; Zagami, AS, 2011)
"The pathophysiology of many types of chronic headaches is not well understood."1.33Cervicogenic headache in patients with presumed migraine: missed diagnosis or misdiagnosis? ( Cook, AJ; Hamill-Ruth, RJ; Rowlingson, JC; Yi, X, 2005)
"Five infusions were given for status migrainosus in three patients, with four of these infusions successfully relieving the headache."1.31Intravenous lignocaine infusions for severe chronic daily headache. ( Hand, PJ; Stark, RJ, 2000)
"In a noncontrolled study, 23 migraine headache patients were treated with intranasal instillation of 0."1.29Rapid and sustained relief of migraine attacks with intranasal lidocaine: preliminary findings. ( Kudrow, DB; Kudrow, L; Sandweiss, JH, 1995)
"Sumatriptan was not used in patients with chronic daily headaches; in the 8 cases of acute migraine or status migrainosus in which it was used, improvement was rapid and complete in seven."1.28The hospital management of severe migrainous headache. ( Goadsby, PJ; Jauslin, P; Lance, JW, 1991)
"In many patients with migraine, several localised areas usually on the scalp or neck can be identified."1.26The treatment of pain trigger areas in migraine. ( Hay, KM, 1976)

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19908 (12.31)18.7374
1990's17 (26.15)18.2507
2000's6 (9.23)29.6817
2010's19 (29.23)24.3611
2020's15 (23.08)2.80

Authors

AuthorsStudies
Gur, STA1
Ahiskalioglu, EO1
Aydin, ME1
Kocak, AO1
Aydin, P1
Ahiskalioglu, A1
Malekian, N1
Bastani, PB1
Oveisgharan, S1
Nabaei, G1
Abdi, S1
Mojica, JJ1
Schwenk, ES3
Lauritsen, C2
Nahas, SJ1
Chowdhury, D2
Mundra, A1
Datta, D1
Duggal, A2
Krishnan, A2
Koul, A2
Ray, JC1
Chen, Z1
Ramsay, G1
Germaine, J1
Hutton, EJ1
Walter, A1
Torjman, MC2
Mukhtar, S1
Patel, HT1
Nardone, B1
Sun, G1
Thota, B1
Lauritsen, CG1
Silberstein, SD3
Tomar, A1
Deorari, V1
Metin, KM1
Dilek, SS1
Karaduman, Y1
Serçe, A1
Takmaz, SA1
İnan, LE1
Evcili, G1
Yabalak, A1
Ebied, AM1
Nguyen, DT1
Dang, T1
Chi, PW2
Hsieh, KY2
Chen, KY1
Hsu, CW2
Bai, CH2
Chen, C2
Hsu, YP2
Lu, F1
Tian, J1
Dong, J1
Zhang, K1
Werner, K1
Qaiser, S1
Kabbouche, M1
Murphy, B1
Maconochie, I1
Hershey, AD1
Laborc, KF1
Spekker, E1
Bohár, Z1
Szűcs, M1
Nagy-Grócz, G1
Fejes-Szabó, A1
Vécsei, L1
Párdutz, Á1
Moaddel, R1
Lovett, J1
Katz, D1
Denk, W1
Wainer, IW1
Hokenek, NM1
Ozer, D2
Yılmaz, E1
Baskaya, N1
Hokenek, UD1
Ak, R1
Guven, R1
Erdogan, MO1
Mepham, LA1
Qureshi, AI1
Pfeiffer, K1
Babar, S1
Huang, W1
Lobanova, I1
Ishfaq, MF1
French, BR1
Siddiq, F1
Gomez, CR1
Çatav, S1
Alkaya Solmaz, F1
Kırdemir, P1
Levin, D1
Cohen, S1
Mellender, S1
Kiss, G1
Amaya-Blas, FJ1
Mecott, GA1
Marfil-Rivera, A1
Tamayo-Esquivel, ML1
García-Pérez, MM1
Chacón-Moreno, H1
Pérez-Porras, S1
Coutiño, R1
Castro-Góvea, Y1
Ayulo, MA1
Phillips, KE1
Tripathi, S1
Tasker, RC1
Viganò, A1
Torrieri, MC1
Toscano, M1
Puledda, F1
Petolicchio, B1
Sasso D'Elia, T1
Verzina, A1
Ruggiero, S1
Altieri, M1
Vicenzini, E1
Schoenen, J1
Di Piero, V1
Bölük, C1
Türk Börü, Ü1
Altun, D1
Taşdemir, M1
Köseoğlu Toksoy, C1
Vanderpol, J1
Jonker, L1
Tsai, CW1
Ilhan Alp, S1
Alp, R1
Kashipazha, D1
Nakhostin-Mortazavi, A1
Mohammadianinejad, SE1
Bahadoram, M1
Zandifar, S1
Tarahomi, S1
Dilli, E1
Halker, R1
Vargas, B1
Hentz, J1
Radam, T1
Rogers, R1
Dodick, D1
Cohen, SP1
Peterlin, BL1
Fulton, L1
Neely, ET1
Kurihara, C1
Gupta, A1
Mali, J1
Fu, DC1
Jacobs, MB1
Plunkett, AR1
Verdun, AJ1
Stojanovic, MP1
Hanling, S1
Constantinescu, O1
White, RL1
McLean, BC1
Pasquina, PF1
Zhao, Z1
Avcu, N1
Doğan, NÖ1
Pekdemir, M1
Yaka, E1
Yılmaz, S1
Alyeşil, C1
Akalın, LE1
Saracco, MG1
Valfrè, W1
Cavallini, M1
Aguggia, M1
Lambert, GA1
Truong, L1
Zagami, AS1
Pfaffenrath, V1
Fenzl, E1
Bregman, D1
Färkkila, M1
Dimitriou, V1
Iatrou, C1
Malefaki, A1
Pratsas, C1
Simopoulos, C1
Voyagis, GS1
DESCOMPS, H1
Amparán-Estrada, S1
Yi, X1
Cook, AJ1
Hamill-Ruth, RJ1
Rowlingson, JC1
Ashkenazi, A1
Matro, R1
Shaw, JW1
Abbas, MA1
Tfelt-Hansen, P1
Olesen, J1
Lous, I1
Maxwell, RE1
Kudrow, L1
Kudrow, DB1
Sandweiss, JH1
Kaube, H1
Goadsby, PJ2
Diamond, ML1
Lane, RJ1
Sachs, CJ1
Tulchinsky, A1
Burstein, R1
Yamamura, H1
Malick, A1
Strassman, AM1
Hand, PJ1
Stark, RJ1
Buckley, R1
McCurry, T1
Gera, J1
Maizels, M2
Geiger, AM1
Hay, KM1
Rothbart, P1
Lewis, GB1
Jauslin, P1
Lance, JW1
Reutens, DC1
Fatovich, DM1
Stewart-Wynne, EG1
Prentice, DA1
Keil, G1
Taubert, K1
Bell, R1
Montoya, D1
Shuaib, A1
Lee, MA1
Shute, WB1
Burke, M2
Barker, PG1
Blumenthal, LS1
Maritano, M1
Marchisio, O1
Ghilardi, F1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Efficacy of Intravenous Lidocaine Infusion in Chronic Unilateral Migraine Headache Clinical and Laboratory Assessment .Aprospective Randomized Double Blind Controlled Study[NCT06109389]Phase 280 participants (Actual)Interventional2023-10-01Active, not recruiting
Comparison of Great Occipital Nerve and Supraorbital Nerve Blockade Treatment Methods Individually and in Combination With Placebo in an Acute Migraine Attack in the Emergency Department, a Prospective, Double Blind, Randomized Controlled Study[NCT04491474]Phase 4128 participants (Actual)Interventional2020-08-15Completed
Greater Occipital Nerve Block for Migraine Prophylaxis[NCT00915473]Phase 470 participants (Actual)Interventional2009-06-30Completed
Comparison of Heated vs. Pulsed Radiofrequency Treatment of the Genicular Nerves for Osteoarthritis Knee Pain[NCT04379895]60 participants (Anticipated)Interventional2020-06-30Not yet recruiting
A Comparison of Pain Control AND Quality of Life Improvement Between Occipital Nerve Block And Occipital Nerve Radiofrequency Ablation: A Double-Blind Single Center Prospective Study[NCT04124458]70 participants (Anticipated)Interventional2023-01-02Not yet recruiting
Pulsed vs Continuous Radiofrequency Neurotomy for Cervical Facet Joint Mediated Pain: a Single-blind Randomized Controlled Clinical Trial[NCT04124445]88 participants (Anticipated)Interventional2020-02-10Recruiting
Randomized, Double-blind, Comparative-effectiveness Study Comparing Corticosteroid Injections to Pulsed Radiofrequency for Occipital Neuralgia[NCT01670825]81 participants (Actual)Interventional2012-08-31Completed
Greater Occipital Nerve Pulsed Radiofrequency for the Treatment of Combined Migraine and Cervicogenic Headache (New Approach): Randomized Clinical Trial[NCT06121037]60 participants (Actual)Interventional2022-01-01Completed
Sphenopalatine Ganglion Blocks for Headaches in the Emergency Department[NCT04255420]Phase 484 participants (Anticipated)Interventional2020-02-21Recruiting
A Prospective, Open-label, Nonrandomized Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain[NCT01471639]37 participants (Actual)Interventional2011-11-30Completed
Intranasal Lidocaine to Treat Pediatric Migraine in the Emergency Department[NCT03576820]Phase 350 participants (Anticipated)Interventional2018-10-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mean Number of Days With Acute Medication Use

"Acute medication use meant the consumption of a drug to abort or terminate a headache." (NCT00915473)
Timeframe: 4 weeks post-injection

Interventiondays per 4 weeks (Mean)
Active Injection6.7
Placebo Injection7.7

Mean Number of Hours With Moderate or Severe Migraine

(NCT00915473)
Timeframe: 4 weeks post-injection

Interventionhours per 4 weeks (Mean)
Active Injection60
Placebo Injection58

Number of Subjects With at Least 50% Reduction in the Frequency of Days With Moderate or Severe Migraine in the 4 Week Post Injection Compared to the 4 Week Pre-injection Baseline Period

The baseline frequency will be the number of calendar days with moderate or severe migraine during the 4 week period prior to injection, and the follow-up frequency will be the number of calendar days with migraine during the 4 week period following injection. (NCT00915473)
Timeframe: 4 weeks pre-injection baseline, 4 weeks post-injection

Interventionparticipants (Number)
Active Injection10
Placebo Injection9

Mean Frequency of Days With a Migraine

(NCT00915473)
Timeframe: 4 weeks post-injection

,
Interventiondays per 4 weeks (Mean)
SevereAt Least ModerateAt Least Mild
Active Injection3.47.09.3
Placebo Injection2.97.810.4

Change in Average Occipital Pain 2 Weeks After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 2 weeks after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 2 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection2.495
Corticosteroid Injection + Sham Pulsed Radiofrequency3.694

Change in Average Occipital Pain 3 Months After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 3 months after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 3 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection3.791
Corticosteroid Injection + Sham Pulsed Radiofrequency4.441

Change in Average Occipital Pain 6 Months After the Start of Treatment

The change in the numeric pain scale score from baseline to 6 months after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 6 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection4.312
Corticosteroid Injection + Sham Pulsed Radiofrequency4.765

Change in Average Occipital Pain 6 Weeks After the Start of Treatment

The change in the numeric pain scale score from baseline to 6 weeks after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 6 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection3.068
Corticosteroid Injection + Sham Pulsed Radiofrequency3.738

Change in Overall Average Headache Pain 2 Weeks After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 2 weeks after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 2 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection3.392
Corticosteroid Injection + Sham Pulsed Radiofrequency4.220

Change in Overall Average Headache Pain 3 Months After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 3 months after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 3 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection4.000
Corticosteroid Injection + Sham Pulsed Radiofrequency4.694

Change in Overall Average Headache Pain 6 Months After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 6 months after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 6 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection6.761
Corticosteroid Injection + Sham Pulsed Radiofrequency7.556

Change in Overall Average Headache Pain 6 Weeks After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 6 weeks after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 6 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection3.678
Corticosteroid Injection + Sham Pulsed Radiofrequency4.410

Change in Overall Worst Headache Pain 2 Weeks After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 2 weeks after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 2 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection5.540
Corticosteroid Injection + Sham Pulsed Radiofrequency6.650

Change in Overall Worst Headache Pain 3 Months After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 3 months after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 3 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection6.522
Corticosteroid Injection + Sham Pulsed Radiofrequency7.417

Change in Overall Worst Headache Pain 6 Months After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 6 months after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 6 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection6.761
Corticosteroid Injection + Sham Pulsed Radiofrequency7.556

Change in Overall Worst Overall Headache Pain 6 Weeks After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 6 weeks after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 6 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection6.583
Corticosteroid Injection + Sham Pulsed Radiofrequency6.825

Change in the Presence of Insomnia 3 Months After the Start of Treatment Measured Using the Athens Insomnia Scale.

This outcome will measure the participant's perceived improvement in sleep using the Athens Insomnia Scale. Scores in this scale can range from 0 to 24. 0 being the best possible outcome and 24 being the worst possible outcome. A score greater than or equal to 6 indicates a presence of insomnia. (NCT01670825)
Timeframe: From baseline to 3 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection9.539
Corticosteroid Injection + Sham Pulsed Radiofrequency9.069

Change in the Presence of Insomnia 6 Months After the Start of Treatment Measured Using the Athens Insomnia Scale.

This outcome will measure the participant's perceived improvement in sleep using the Athens Insomnia Scale. Scores in this scale can range from 0 to 24. 0 being the best possible outcome and 24 being the worst possible outcome. A score greater than or equal to 6 indicates a presence of insomnia. (NCT01670825)
Timeframe: From baseline to 6 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection9.256
Corticosteroid Injection + Sham Pulsed Radiofrequency9.431

Change in the Presence of Insomnia 6 Weeks After the Start of Treatment Measured Using the Athens Insomnia Scale.

This outcome will measure the participant's perceived improvement in sleep using the Athens Insomnia Scale. Scores in this scale can range from 0 to 24. 0 being the best possible outcome and 24 being the worst possible outcome. A score greater than or equal to 6 indicates a presence of insomnia. (NCT01670825)
Timeframe: From baseline to 6 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection10.025
Corticosteroid Injection + Sham Pulsed Radiofrequency8.132

Change in the Severity of Depression 3 Months After the Start of Treatment Measured Using the Beck's Depression Inventory

This outcome will measure the change in severity of depression using the Beck's Depression Inventory. Scores in this inventory can range from 0 to 63. 0 being the best possible outcome and 63 being the worst possible outcome. A score between 14 and 19 indicates mild depression and a score greater than or equal 29 indicates severe depression. (NCT01670825)
Timeframe: From baseline to 3 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection11.333
Corticosteroid Injection + Sham Pulsed Radiofrequency11.972

Change in the Severity of Depression 6 Months After the Start of Treatment Measured Using the Beck's Depression Inventory

This outcome will measure the change in severity of depression using the Beck's Depression Inventory. Scores in this inventory can range from 0 to 63. 0 being the best possible outcome and 63 being the worst possible outcome. A score between 14 and 19 indicates mild depression and a score greater than or equal 29 indicates severe depression. (NCT01670825)
Timeframe: From baseline to 6 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection12.590
Corticosteroid Injection + Sham Pulsed Radiofrequency12.250

Change in the Severity of Depression 6 Weeks After the Start of Treatment Measured Using the Beck's Depression Inventory

This outcome will measure the change in severity of depression using the Beck's Depression Inventory. Scores in this inventory can range from 0 to 63. 0 being the best possible outcome and 63 being the worst possible outcome. A score between 14 and 19 indicates mild depression and a score greater than or equal 29 indicates severe depression. (NCT01670825)
Timeframe: From baseline to 6 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection12.775
Corticosteroid Injection + Sham Pulsed Radiofrequency10.842

Change in Worst Occipital Pain 2 Weeks After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 2 weeks after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 2 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection4.726
Corticosteroid Injection + Sham Pulsed Radiofrequency5.846

Change in Worst Occipital Pain 3 Months After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 3 months after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 3 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection5.850
Corticosteroid Injection + Sham Pulsed Radiofrequency7.149

Change in Worst Occipital Pain 6 Months After the Start of Treatment

This outcome measures the change in the numeric pain scale score from baseline to 6 months after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 6 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection6.705
Corticosteroid Injection + Sham Pulsed Radiofrequency7.541

Change in Worst Occipital Pain 6 Weeks After the Start of Treatment

The change in the numeric pain scale score from baseline to 6 weeks after treatment. The scale ranges from 0-10. The minimum score is 0 which is defined as no pain and the maximum score is 10, which is defined as the worst pain imaginable. The best possible outcome would be a 0. The worst possible outcome would be a 10. (NCT01670825)
Timeframe: From baseline to 6 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection5.354
Corticosteroid Injection + Sham Pulsed Radiofrequency6.064

Disability Due to Headaches 3 Months After the Start of Treatment Measured Using the Headache Impact Scale

This outcome measures what the patient feels they cannot do because headaches. This outcome is measured using the Headache Impact Test. Scores in this test range from range from 36 to 78, with higher scores indicating greater negative impact. A score of less than 50 indicates minimal impact, while a score greater than or equal to 60 indicates headaches are severely impacting one's life. (NCT01670825)
Timeframe: From baseline to 3 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection59.718
Corticosteroid Injection + Sham Pulsed Radiofrequency60.556

Disability Due to Headaches 6 Months After the Start of Treatment Measured Using the Headache Impact Scale

This outcome measures what the patient feels they cannot do because headaches. This outcome is measured using the Headache Impact Test. Scores in this test range from range from 36 to 78, with higher scores indicating greater negative impact. A score of less than 50 indicates minimal impact, while a score greater than or equal to 60 indicates headaches are severely impacting one's life. (NCT01670825)
Timeframe: From baseline to 6 months after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection59.641
Corticosteroid Injection + Sham Pulsed Radiofrequency61.389

Disability Due to Headaches 6 Weeks After the Start of Treatment Measured Using the Headache Impact Scale

This outcome measures what the patient feels they cannot do because headaches. This outcome is measured using the Headache Impact Test. Scores in this test range from range from 36 to 78, with higher scores indicating greater negative impact. A score of less than 50 indicates minimal impact, while a score greater than or equal to 60 indicates headaches are severely impacting one's life. (NCT01670825)
Timeframe: From baseline to 6 weeks after the start of treatment

Interventionunits on a scale (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection60.087
Corticosteroid Injection + Sham Pulsed Radiofrequency59.553

Severe Headache Frequency for Migraine Headaches 3 Months After the Start of Treatment Measured Asking the Number of Severe Headache Days 1 Week Prior to Study Visit

This outcome will measure the number of days the patient has severe migraine headaches in the week (7 days) prior to the 3 month follow-up visit. A severe headache is defined as a headache with a score greater than or equal to 7 on the numeric pain scale. (NCT01670825)
Timeframe: From baseline to 3 months after the start of treatment

Interventiondays (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection2.087
Corticosteroid Injection + Sham Pulsed Radiofrequency2.263

Severe Headache Frequency for Migraine Headaches 6 Months After the Start of Treatment Measured Asking the Number of Severe Headache Days 1 Week Prior to Study Visit

This outcome will measure the number of days the patient has severe migraine headaches in the week (7 days) prior to the 6 month follow-up visit. A severe headache is defined as a headache with a score greater than or equal to 7 on the numeric pain scale. (NCT01670825)
Timeframe: From baseline to 6 months after the start of treatment

Interventiondays (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection2.044
Corticosteroid Injection + Sham Pulsed Radiofrequency2.368

Severe Headache Frequency for Migraine Headaches 6 Weeks After the Start of Treatment Measured Asking the Number of Severe Headaches in the Past Week.

This outcome will measure the number of days the patient has severe migraine headaches in the week (7 days) prior to the 6 week follow-up visit. A severe headache is defined as a headache with a score greater than or equal to 7 on the numeric pain scale. (NCT01670825)
Timeframe: From baseline to 6 weeks after the start of treatment

Interventiondays (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection1.708
Corticosteroid Injection + Sham Pulsed Radiofrequency1.810

Severe Headache Frequency for Occipital Neuralgia Headaches 3 Months After the Start of Treatment Measured Asking the Number of Severe Headache Days 1 Week Prior to Study Visit

This outcome will measure the number of days the patient has severe occipital neuralgia headaches in the week (7 days) prior to the 6 week follow-up visit. A severe headache is defined as a headache with a score greater than or equal to 7 on the numeric pain scale. (NCT01670825)
Timeframe: 3 months

Interventiondays (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection1.846
Corticosteroid Injection + Sham Pulsed Radiofrequency1.919

Severe Headache Frequency for Occipital Neuralgia Headaches 6 Months After the Start of Treatment Measured Asking the Number of Severe Headache Days 1 Week Prior to Study Visit

This outcome will measure the number of days the patient has severe occipital neuralgia headaches in the week (7 days) prior to the 6 week follow-up visit. A severe headache is defined as a headache with a score greater than or equal to 7 on the numeric pain scale. (NCT01670825)
Timeframe: From baseline to 6 months after the start of treatment

Interventiondays (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection2.128
Corticosteroid Injection + Sham Pulsed Radiofrequency2.162

Severe Headache Frequency for Occipital Neuralgia Headaches 6 Weeks After the Start of Treatment Measured Asking the Number of Severe Headache Days 1 Week Prior to Study Visit

This outcome will measure the number of days the patient has severe occipital neuralgia headaches in the week (7 days) prior to the 6 week follow-up visit. A severe headache is defined as a headache with a score greater than or equal to 7 on the numeric pain scale. (NCT01670825)
Timeframe: From baseline to 6 weeks after the start of treatment

Interventiondays (Mean)
Pulsed Radiofrequency + Local Anesthetic Injection1.436
Corticosteroid Injection + Sham Pulsed Radiofrequency1.436

Efficacy of Intranasal Ketorolac on Numeric Pain Scale

Change in numeric rating scale after receiving intranasal ketorolac. 0 (no pain) - 10 (worst possible pain) (NCT01471639)
Timeframe: up to 4 hours

InterventionParticipants (Count of Participants)
Baseline7213042920 minutes7213042940 minutes721304291 hour721304292 hoiurs721304293 hours721304294 hours72130429
Reported Pain Score of 10Reported Pain Score of 9Reported Pain Score of 8Reported Pain Score of 7Reported Pain Score of 6Reported Pain Score of 5Reported Pain Score of 4REported Pain Score of 3Reported Pain Score of 2Reported Pain Score of 1Reported Pain Score of 0No Rating
Intranasal Ketorolac (Sprix)12
Intranasal Ketorolac (Sprix)3
Intranasal Ketorolac (Sprix)2
Intranasal Ketorolac (Sprix)6
Intranasal Ketorolac (Sprix)4
Intranasal Ketorolac (Sprix)5
Intranasal Ketorolac (Sprix)10
Intranasal Ketorolac (Sprix)0
Intranasal Ketorolac (Sprix)1
Intranasal Ketorolac (Sprix)29
Intranasal Ketorolac (Sprix)36
Intranasal Ketorolac (Sprix)37

Reviews

4 reviews available for lidocaine and Abdominal Migraine

ArticleYear
Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine.
    Current pain and headache reports, 2021, Dec-11, Volume: 25, Issue:12

    Topics: Analgesics; Humans; Ketamine; Lidocaine; Migraine Disorders; Prospective Studies

2021
Intranasal lidocaine for acute migraine: A meta-analysis of randomized controlled trials.
    PloS one, 2019, Volume: 14, Issue:10

    Topics: Acute Disease; Administration, Intranasal; Humans; Lidocaine; Migraine Disorders; Randomized Control

2019
Intravenous Migraine Treatment in Children and Adolescents.
    Current pain and headache reports, 2020, Jul-08, Volume: 24, Issue:8

    Topics: Administration, Intravenous; Adolescent; Akathisia, Drug-Induced; Anesthetics, Local; Anti-Inflammat

2020
Intranasal lidocaine for acute migraine: A protocol for the systematic review of randomized clinical trials.
    Medicine, 2019, Volume: 98, Issue:20

    Topics: Acute Disease; Administration, Intranasal; Anesthetics, Local; Humans; Lidocaine; Migraine Disorders

2019

Trials

20 trials available for lidocaine and Abdominal Migraine

ArticleYear
Intravenous lidocaine vs. NSAIDs for migraine attack in the ED: a prospective, randomized, double-blind study.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:1

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Hum

2022
Preventive effect of greater occipital nerve block on patients with episodic migraine: A randomized double-blind placebo-controlled clinical trial.
    Cephalalgia : an international journal of headache, 2022, Volume: 42, Issue:6

    Topics: Adult; Headache; Humans; Iran; Lidocaine; Migraine Disorders; Nerve Block; Triamcinolone

2022
Efficacy and tolerability of combination treatment of topiramate and greater occipital nerve block versus topiramate monotherapy for the preventive treatment of chronic migraine: A randomized controlled trial.
    Cephalalgia : an international journal of headache, 2022, Volume: 42, Issue:9

    Topics: Adult; Double-Blind Method; Fructose; Headache; Humans; Lidocaine; Migraine Disorders; Nerve Block;

2022
Status migrainosus inpatient treatment with eptinezumab (SMITE): study protocol for a randomised controlled trial.
    BMJ open, 2022, 03-08, Volume: 12, Issue:3

    Topics: Antibodies, Monoclonal, Humanized; Double-Blind Method; Hospitalization; Humans; Inpatients; Lidocai

2022
Greater occipital nerve blockade for the preventive treatment of chronic migraine: A randomized double-blind placebo-controlled study.
    Cephalalgia : an international journal of headache, 2023, Volume: 43, Issue:2

    Topics: Double-Blind Method; Headache; Humans; Lidocaine; Migraine Disorders; Nerve Block; Treatment Outcome

2023
Comparison of greater occipital nerve and supra orbital nerve blocks methods in the treatment of acute migraine attack: A randomized double-blind controlled trial.
    Clinical neurology and neurosurgery, 2021, Volume: 207

    Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Male; Migraine Disorders;

2021
Effectiveness of surgical treatment in chronic migraine.
    Cirugia y cirujanos, 2018, Volume: 86, Issue:1

    Topics: Adolescent; Adult; Chronic Disease; Decompression, Surgical; Facial Muscles; Female; Humans; Lidocai

2018
Greater occipital and supraorbital nerve blockade for the preventive treatment of migraine: a single-blind, randomized, placebo-controlled study.
    Current medical research and opinion, 2019, Volume: 35, Issue:5

    Topics: Adult; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Migraine Disorders; Nerve B

2019
Preventive effect of greater occipital nerve block on severity and frequency of migraine headache.
    Global journal of health science, 2014, Jul-29, Volume: 6, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Cranial Nerves; Double-Blind

2014
Occipital nerve block for the short-term preventive treatment of migraine: A randomized, double-blinded, placebo-controlled study.
    Cephalalgia : an international journal of headache, 2015, Volume: 35, Issue:11

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anesthetics, Local; Bupivacaine; Double-Blind Meth

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Double-Blind Method; Drug Thera

2015
Intranasal Lidocaine in Acute Treatment of Migraine: A Randomized Controlled Trial.
    Annals of emergency medicine, 2017, Volume: 69, Issue:6

    Topics: Acute Disease; Administration, Intranasal; Adult; Anesthetics, Local; Antiemetics; Double-Blind Meth

2017
Greater occipital nerve block in chronic migraine.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2010, Volume: 31 Suppl 1

    Topics: Anesthetics, Local; Bupivacaine; Humans; Lidocaine; Migraine Disorders; Nerve Block; Peripheral Nerv

2010
Intranasal ketorolac tromethamine (SPRIX(R)) containing 6% of lidocaine (ROX-828) for acute treatment of migraine: safety and efficacy data from a phase II clinical trial.
    Cephalalgia : an international journal of headache, 2012, Volume: 32, Issue:10

    Topics: Administration, Intranasal; Adolescent; Adult; Anesthetics, Local; Cyclooxygenase Inhibitors; Double

2012
Blockade of branches of the ophthalmic nerve in the management of acute attack of migraine.
    Middle East journal of anaesthesiology, 2002, Volume: 16, Issue:5

    Topics: Acute Disease; Adult; Anesthetics, Local; Epinephrine; Female; Humans; Lidocaine; Middle Aged; Migra

2002
Greater occipital nerve block using local anaesthetics alone or with triamcinolone for transformed migraine: a randomised comparative study.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:4

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Cranial Nerves; Drug Therapy, Comb

2008
Lignocaine versus saline in migraine pain.
    Lancet (London, England), 1980, May-24, Volume: 1, Issue:8178

    Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Injections, Intramuscular; Lidocaine; Migrain

1980
Intranasal lidocaine for migraine: a randomized trial and open-label follow-up.
    Headache, 1999, Volume: 39, Issue:8

    Topics: Administration, Intranasal; Adult; Anesthetics, Local; Double-Blind Method; Female; Follow-Up Studie

1999
Intranasal lidocaine for migraine: a randomized trial and open-label follow-up.
    Headache, 1999, Volume: 39, Issue:8

    Topics: Administration, Intranasal; Adult; Anesthetics, Local; Double-Blind Method; Female; Follow-Up Studie

1999
Intranasal lidocaine for migraine: a randomized trial and open-label follow-up.
    Headache, 1999, Volume: 39, Issue:8

    Topics: Administration, Intranasal; Adult; Anesthetics, Local; Double-Blind Method; Female; Follow-Up Studie

1999
Intranasal lidocaine for migraine: a randomized trial and open-label follow-up.
    Headache, 1999, Volume: 39, Issue:8

    Topics: Administration, Intranasal; Adult; Anesthetics, Local; Double-Blind Method; Female; Follow-Up Studie

1999
Is intravenous lidocaine clinically effective in acute migraine?
    Cephalalgia : an international journal of headache, 1991, Volume: 11, Issue:6

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male;

1991
A comparative trial of three agents in the treatment of acute migraine headache.
    Annals of emergency medicine, 1990, Volume: 19, Issue:10

    Topics: Adult; Chlorpromazine; Dihydroergotamine; Emergencies; Follow-Up Studies; Humans; Infusions, Intrave

1990

Other Studies

41 other studies available for lidocaine and Abdominal Migraine

ArticleYear
Lidocaine infusions for refractory chronic migraine: a retrospective analysis.
    Regional anesthesia and pain medicine, 2022, Volume: 47, Issue:7

    Topics: Adult; Aftercare; Female; Headache; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Mi

2022
The effects of greater occipital nerve blockage with lidocaine on sleep characteristics in chronic migraine patients.
    Clinical neurology and neurosurgery, 2023, Volume: 231

    Topics: Adult; Female; Humans; Lidocaine; Middle Aged; Migraine Disorders; Pain; Sleep; Sleep Initiation and

2023
Evaluation of the efficacy of peripheral nerve block alone in episodic and chronic migraine patients.
    Arquivos de neuro-psiquiatria, 2023, Volume: 81, Issue:8

    Topics: Anesthetics, Local; Humans; Lidocaine; Migraine Disorders; Peripheral Nerves; Retrospective Studies;

2023
Evaluation of Occipital Nerve Blocks for Acute Pain Relief of Migraines.
    Journal of clinical pharmacology, 2020, Volume: 60, Issue:3

    Topics: Acute Pain; Adult; Aged; Anesthetics, Local; Bupivacaine; Dexamethasone; Female; Florida; Glucocorti

2020
Tonic-clonic seizure during the ultrasound-guided stellate ganglion block because of an injection into an unrecognized variant vertebral artery: A case report.
    Medicine, 2019, Volume: 98, Issue:48

    Topics: Adult; Anesthetics, Local; Autonomic Nerve Block; Humans; Intraoperative Complications; Lidocaine; M

2019
Trigeminal activation patterns evoked by chemical stimulation of the dura mater in rats.
    The journal of headache and pain, 2020, Aug-15, Volume: 21, Issue:1

    Topics: Animals; Dura Mater; Freund's Adjuvant; Headache; Inflammation; Lidocaine; Male; Migraine Disorders;

2020
Ketamine for Refractory Chronic Migraine: An Observational Pilot Study and Metabolite Analysis.
    Journal of clinical pharmacology, 2021, Volume: 61, Issue:11

    Topics: Adult; Analgesics; Chronic Disease; Female; Humans; Ketamine; Lidocaine; Male; Middle Aged; Migraine

2021
Intra-arterial injection of lidocaine into middle meningeal artery to treat intractable headaches and severe migraine.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2021, Volume: 31, Issue:6

    Topics: Headache Disorders; Humans; Injections, Intra-Arterial; Lidocaine; Meningeal Arteries; Migraine Diso

2021
[The results of greater occipital nerve block applied for migraine headache].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2017, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Migraine

2017
Sphenopalatine Ganglion Block Successfully Treats Migraines in a Type 1 Arnold Chiari Malformation Pregnant Patient: A Case Report.
    A&A practice, 2018, Jul-15, Volume: 11, Issue:2

    Topics: Administration, Intranasal; Adult; Anesthetics, Local; Arnold-Chiari Malformation; Female; Humans; L

2018
Safety and Efficacy of IV Lidocaine in the Treatment of Children and Adolescents With Status Migraine.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2018, Volume: 19, Issue:8

    Topics: Adolescent; Anesthetics, Local; Child; Female; Humans; Infusions, Intravenous; Intensive Care Units,

2018
IV Lidocaine for Status Migraine: Making an "Off-Label" Treatment Decision.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2018, Volume: 19, Issue:8

    Topics: Adolescent; Child; Humans; Lidocaine; Migraine Disorders; Off-Label Use

2018
Neurophysiological correlates of clinical improvement after greater occipital nerve (GON) block in chronic migraine: relevance for chronic migraine pathophysiology.
    The journal of headache and pain, 2018, Aug-20, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Anesthetics, Local; Autonomic Nerve Block; Betamethasone; Chronic Disease; Evoked

2018
Influence of patient positioning on reported clinical outcomes after greater occipital nerve block for treatment of headache: Results from prospective single-centre, non-randomised, proof-of-concept study.
    Clinical neurology and neurosurgery, 2019, Volume: 176

    Topics: Adult; Anesthesia, Conduction; Anesthetics, Local; Headache; Humans; Lidocaine; Middle Aged; Migrain

2019
Supraorbital and infraorbital nerve blockade in migraine patients: results of 6-month clinical follow-up.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:13

    Topics: Adult; Anesthetics, Local; Disability Evaluation; Female; Follow-Up Studies; Humans; Lidocaine; Male

2013
Effect of cortical spreading depression on basal and evoked traffic in the trigeminovascular sensory system.
    Cephalalgia : an international journal of headache, 2011, Volume: 31, Issue:14

    Topics: Anesthetics, Local; Animals; Cortical Spreading Depression; Dura Mater; Electric Stimulation; Evoked

2011
[STIMULATION OF HYPOTHALAMO-HYPOPHYSIAL SECRETIONS IN MAN BY RETRO-STYLOID ANESTHETIC INFILTRATION].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1963, Sep-10, Volume: 39

    Topics: Adrenocorticotropic Hormone; Anesthetics; Asthma; Autonomic Nerve Block; Eczema; Endocrinology; Huma

1963
Management of acute migraine headache with lidocaine.
    Plastic and reconstructive surgery, 2005, Volume: 116, Issue:1

    Topics: Anesthetics, Local; Botulinum Toxins, Type A; Humans; Lidocaine; Migraine Disorders; Neuromuscular A

2005
Cervicogenic headache in patients with presumed migraine: missed diagnosis or misdiagnosis?
    The journal of pain, 2005, Volume: 6, Issue:10

    Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cervical Plexus; Cervical Vertebrae; Chronic Disease;

2005
Surgical control of chronic migrainous neuralgia by trigeminal ganglio-rhizolysis.
    Journal of neurosurgery, 1982, Volume: 57, Issue:4

    Topics: Adult; Chronic Disease; Ergotamine; Humans; Lidocaine; Lithium; Male; Methysergide; Middle Aged; Mig

1982
Rapid and sustained relief of migraine attacks with intranasal lidocaine: preliminary findings.
    Headache, 1995, Volume: 35, Issue:2

    Topics: Administration, Intranasal; Adult; Clinical Trials as Topic; Female; Humans; Lidocaine; Male; Middle

1995
Anti-migraine compounds fail to modulate the propagation of cortical spreading depression in the cat.
    European neurology, 1994, Volume: 34, Issue:1

    Topics: Analgesics; Animals; Aspirin; Cats; Cerebral Cortex; Clonazepam; Cortical Spreading Depression; Dihy

1994
Intranasal lidocaine for treatment of migraine.
    JAMA, 1996, Nov-20, Volume: 276, Issue:19

    Topics: Acute Disease; Administration, Intranasal; Humans; Lidocaine; Migraine Disorders

1996
Intranasal lidocaine for treatment of migraine.
    JAMA, 1996, Nov-20, Volume: 276, Issue:19

    Topics: Acute Disease; Diagnosis, Differential; Humans; Lidocaine; Migraine Disorders; Tomography, X-Ray Com

1996
Intranasal lidocaine for treatment of migraine.
    JAMA, 1996, Nov-20, Volume: 276, Issue:19

    Topics: Acute Disease; Administration, Intranasal; Humans; Lidocaine; Migraine Disorders

1996
Intranasal lidocaine for treatment of migraine.
    JAMA, 1996, Nov-20, Volume: 276, Issue:19

    Topics: Acute Disease; Administration, Inhalation; Humans; Lidocaine; Migraine Disorders

1996
Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons.
    Journal of neurophysiology, 1998, Volume: 79, Issue:2

    Topics: Anesthetics, Local; Animals; Bradykinin; Brain Stem; Dinoprostone; Dura Mater; Electric Stimulation;

1998
Intravenous lignocaine infusions for severe chronic daily headache.
    The Medical journal of Australia, 2000, Feb-21, Volume: 172, Issue:4

    Topics: Adolescent; Adult; Anesthetics, Local; Chronic Disease; Clinical Protocols; Drug Monitoring; Female;

2000
Intranasal lidocaine for migraine using a metered-dose spray.
    Headache, 2000, Volume: 40, Issue:6

    Topics: Administration, Intranasal; Anesthetics, Local; Humans; Lidocaine; Migraine Disorders; Nebulizers an

2000
Intranasal lidocaine to prevent headache following migraine aura.
    Headache, 1999, Volume: 39, Issue:6

    Topics: Administration, Intranasal; Adolescent; Facial Nerve; Humans; Lidocaine; Male; Migraine Disorders; T

1999
The treatment of pain trigger areas in migraine.
    The Journal of the Royal College of General Practitioners, 1976, Volume: 26, Issue:166

    Topics: Adult; Epinephrine; Female; Humans; Lidocaine; Male; Middle Aged; Migraine Disorders

1976
Unilateral headache with features of hemicrania continua and cervicogenic headache--a case report.
    Headache, 1992, Volume: 32, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Female; Headache; Humans; Injections, Spinal; Lidocaine; Methylpred

1992
Lignocaine suppositories for migraine.
    Anaesthesia and intensive care, 1992, Volume: 20, Issue:4

    Topics: Adult; Humans; Lidocaine; Migraine Disorders; Suppositories

1992
The hospital management of severe migrainous headache.
    Headache, 1991, Volume: 31, Issue:10

    Topics: Adolescent; Adult; Aged; Child; Dihydroergotamine; Drug Therapy, Combination; Female; Humans; Indole

1991
[Can reflexotherapy of the pelvis eliminate or improve a migraine?].
    Zeitschrift fur arztliche Fortbildung, 1991, Jan-25, Volume: 85, Issue:1-2

    Topics: Adolescent; Adult; Child; Combined Modality Therapy; Female; Humans; Lidocaine; Male; Manipulation,

1991
Migraine headache--a long-term approach.
    Zentralblatt fur Gynakologie, 1990, Volume: 112, Issue:20

    Topics: Adult; Female; Humans; Injections; Lidocaine; Middle Aged; Migraine Disorders; Myofascial Pain Syndr

1990
Intravenous lignocaine.
    Australian family physician, 1990, Volume: 19, Issue:4

    Topics: Humans; Infusions, Intravenous; Lidocaine; Migraine Disorders

1990
Intravenous lignocaine for migraine headache.
    Australian family physician, 1989, Volume: 18, Issue:12

    Topics: Aspirin; Humans; Injections, Intravenous; Lidocaine; Metoclopramide; Migraine Disorders

1989
Treatment for migraine.
    The Medical journal of Australia, 1986, Jan-06, Volume: 144, Issue:1

    Topics: Humans; Lidocaine; Migraine Disorders

1986
Injury to the cervical spine as a cause of headache.
    Postgraduate medicine, 1974, Volume: 56, Issue:3

    Topics: Adolescent; Female; Head; Headache; Humans; Lidocaine; Male; Middle Aged; Migraine Disorders; Palpat

1974
[Atypical neurovascular pains in the head. Relation between sphygmographic charges caused by anesthetic block and the antalgic effect].
    Minerva anestesiologica, 1967, Volume: 33, Issue:2

    Topics: Adult; Aged; Anesthesia, Conduction; Cerebrovascular Circulation; Epinephrine; Facial Neuralgia; Fem

1967