Page last updated: 2024-10-28

lidocaine and 2019 Novel Coronavirus Disease

lidocaine has been researched along with 2019 Novel Coronavirus Disease in 15 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Compound lidocaine/prilocaine cream combined with tetracaine may be a more effective approach for preventing coughing and stabilising circulation during extubation following general anaesthesia."9.69Compound lidocaine/prilocaine cream combined with tetracaine prevents cough caused by extubation after general anaesthesia: a randomised controlled trial. ( Gao, J; Li, T; Li, Y; Wang, M; Zhang, E; Zhang, H; Zhang, L; Zhao, X, 2023)
"Compound lidocaine/prilocaine cream combined with tetracaine may be a more effective approach for preventing coughing and stabilising circulation during extubation following general anaesthesia."5.69Compound lidocaine/prilocaine cream combined with tetracaine prevents cough caused by extubation after general anaesthesia: a randomised controlled trial. ( Gao, J; Li, T; Li, Y; Wang, M; Zhang, E; Zhang, H; Zhang, L; Zhao, X, 2023)
"The main objective of this study is to evaluate the effect of intravenous lidocaine on gas exchange and inflammation in acute respiratory distress syndrome due or not to Covid-19 pneumonia."5.41Impact of intravenous lidocaine on clinical outcomes of patients with ARDS during COVID-19 pandemia (LidoCovid): A structured summary of a study protocol for a randomised controlled trial. ( Aberkane, O; Becker, G; Chamaraux-Tran, TN; Glady, L; Harlay, ML; Hecketsweiler, S; Julians, M; Lefebvre, F; Muller, C; Muller, M; Pottecher, J; Romoli, A; Schneider, F; Tawk, M, 2021)
"Severe cases of Coronavirus Disease 2019 (COVID-19) that require admission to the Intensive Care Unit (ICU) and mechanical ventilation assistance show a high mortality rate with currently few therapeutic options available."1.91Lidocaine reinforces the anti-inflammatory action of dexamethasone on myeloid and epithelial cells activated by inflammatory cytokines or SARS-CoV-2 infection. ( Baumeister, E; Correger, E; Docena, G; Elizagaray, ML; Mazitelli, I; Pontoriero, A; Raimondi, C; Rumbo, M, 2023)
"Oral manifestations of coronavirus disease 2019 (COVID-19), including ulcers, herpetiform lesions, macules, and petechiae, among others, are becoming increasingly recognized, but there is little guidance on their treatment."1.72Conservative treatment with mouthwashes followed by tongue photo biomodulation therapy in Covid-19: a case report. ( Asif, A; Chaughtai, S; Chaughtai, Z, 2022)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's15 (100.00)2.80

Authors

AuthorsStudies
Barman, R1
Clark, K1
Olatoye, O1
Hasan, D1
Shono, A1
van Kalken, CK1
van der Spek, PJ1
Krenning, EP1
Kotani, T1
Elizagaray, ML1
Mazitelli, I1
Pontoriero, A1
Baumeister, E1
Docena, G1
Raimondi, C1
Correger, E1
Rumbo, M1
Huo, J1
Chen, C1
Gao, D1
Yang, L1
Qu, R1
Jiang, H1
Chen, X2
Guo, Y1
Zhu, S1
Ou, D1
Zhao, L1
Chaughtai, S1
Chaughtai, Z1
Asif, A1
Zhang, E1
Zhao, X1
Li, T3
Wang, M1
Gao, J1
Zhang, H1
Li, Y1
Zhang, L1
Liu, X1
Zheng, F1
Tian, L1
Zhang, Z1
Ren, Z1
Chen, W1
Li, K1
Sheng, J1
Aminnejad, R1
Salimi, A1
Saeidi, M1
Ali, ZA1
El-Mallakh, RS1
Finnerty, DT1
Buggy, DJ1
Kanodia, A1
Srigyan, D1
Sikka, K1
Choudhary, A1
Choudekar, A1
Mittal, S1
Bhopale, SA1
Dar, L1
Thakar, A1
Jain, A1
Lamperti, M1
Doyle, DJ1
Turcotte, JJ1
Petre, BM1
Jones, CM1
Gelfand, JM1
Giardino, FR1
Cuomo, R1
Sisti, A1
Han, J1
Giuseppe, N1
Grimaldi, L1
Muller, M1
Lefebvre, F1
Harlay, ML1
Glady, L1
Becker, G1
Muller, C1
Aberkane, O1
Tawk, M1
Julians, M1
Romoli, A1
Hecketsweiler, S1
Schneider, F1
Pottecher, J1
Chamaraux-Tran, TN1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Intravenous Lidocaine on Clinical Outcomes of Patients With ARDS During COVID-19 Pandemia[NCT04609865]Phase 3100 participants (Anticipated)Interventional2020-11-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lidocaine and 2019 Novel Coronavirus Disease

ArticleYear
A novel definition and treatment of hyperinflammation in COVID-19 based on purinergic signalling.
    Purinergic signalling, 2022, Volume: 18, Issue:1

    Topics: Adenosine Triphosphate; Anti-Inflammatory Agents; COVID-19; Critical Care; Cytokine Release Syndrome

2022

Trials

2 trials available for lidocaine and 2019 Novel Coronavirus Disease

ArticleYear
Compound lidocaine/prilocaine cream combined with tetracaine prevents cough caused by extubation after general anaesthesia: a randomised controlled trial.
    BMC anesthesiology, 2023, 01-03, Volume: 23, Issue:1

    Topics: Airway Extubation; Anesthesia, General; Anesthetics, Local; Cough; COVID-19; Double-Blind Method; Ep

2023
Impact of intravenous lidocaine on clinical outcomes of patients with ARDS during COVID-19 pandemia (LidoCovid): A structured summary of a study protocol for a randomised controlled trial.
    Trials, 2021, Feb-11, Volume: 22, Issue:1

    Topics: Administration, Intravenous; Clinical Trials, Phase III as Topic; COVID-19; COVID-19 Drug Treatment;

2021

Other Studies

12 other studies available for lidocaine and 2019 Novel Coronavirus Disease

ArticleYear
Short-Term Lidocaine Infusion as a Nonsedative Option to Maintain Ventilator Synchrony During Opioid Tapering in a COVID-19 Patient.
    Pain medicine (Malden, Mass.), 2022, 03-02, Volume: 23, Issue:3

    Topics: Analgesics, Opioid; COVID-19; Humans; Infusions, Intravenous; Lidocaine; SARS-CoV-2; Ventilators, Me

2022
Lidocaine reinforces the anti-inflammatory action of dexamethasone on myeloid and epithelial cells activated by inflammatory cytokines or SARS-CoV-2 infection.
    Biomedical journal, 2023, Volume: 46, Issue:1

    Topics: Anti-Inflammatory Agents; COVID-19; COVID-19 Drug Treatment; Cytokines; Dexamethasone; Epithelial Ce

2023
Ultrasound-Guided Capsular Thyroid Injection Therapy With Dexamethasone and Lidocaine Mixture for Subacute Thyroiditis: A Single-Center Study.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2023, Volume: 42, Issue:3

    Topics: COVID-19; COVID-19 Drug Treatment; Dexamethasone; Humans; Hypothyroidism; Lidocaine; Pain; Thyroidit

2023
Conservative treatment with mouthwashes followed by tongue photo biomodulation therapy in Covid-19: a case report.
    Journal of medical case reports, 2022, Oct-06, Volume: 16, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Antiviral Agents; Conservative Treatment; COVID-19;

2022
Lidocaine inhibits influenza a virus replication by up-regulating IFNα4 via TBK1-IRF7 and JNK-AP1 signaling pathways.
    International immunopharmacology, 2023, Volume: 115

    Topics: Animals; Antiviral Agents; COVID-19; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Inf

2023
Lidocaine during intubation and extubation in patients with coronavirus disease (COVID-19).
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2020, Volume: 67, Issue:6

    Topics: Airway Extubation; Anesthesiology; Betacoronavirus; Coronavirus; Coronavirus Infections; COVID-19; C

2020
Nebulized Lidocaine in COVID-19, An Hypothesis.
    Medical hypotheses, 2020, Volume: 144

    Topics: Administration, Inhalation; Anesthetics, Local; Anti-Inflammatory Agents; COVID-19; COVID-19 Drug Tr

2020
A novel role for lidocaine in COVID-19 patients?
    British journal of anaesthesia, 2020, Volume: 125, Issue:4

    Topics: Anesthetics, Local; Coronavirus Infections; COVID-19; Cytokines; Extracellular Traps; Humans; Lidoca

2020
Topical lignocaine anaesthesia for oropharyngeal sampling for COVID-19.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021, Volume: 278, Issue:5

    Topics: Adult; Anesthesia; COVID-19; Humans; Lidocaine; Oropharynx; RNA, Viral; SARS-CoV-2

2021
Dexmedetomidine: another arrow in the quiver to fight COVID-19 in intensive care units.
    British journal of anaesthesia, 2021, Volume: 126, Issue:1

    Topics: COVID-19; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Lidocaine; SARS-Co

2021
Maintaining Access to Orthopaedic Surgery During Periods of Operating Room Resource Constraint: Expanded Use of Wide-Awake Surgery During the COVID-19 Pandemic.
    Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2020, 12-15, Volume: 4, Issue:12

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; COVID-19; Epinephrine; Female; Hemostatics; Huma

2020
Taking care of healthcare workers during COVID-19 pandemic: does plastic surgery have a role?
    Acta bio-medica : Atenei Parmensis, 2020, 11-10, Volume: 91, Issue:4

    Topics: Anesthetics, Local; Burnout, Professional; Collagen; COVID-19; Health Personnel; Humans; Infectious

2020