licochalcone-a and Sarcoma

licochalcone-a has been researched along with Sarcoma* in 1 studies

Other Studies

1 other study(ies) available for licochalcone-a and Sarcoma

Article	Year
Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor. Bioorganic & medicinal chemistry letters, 2020, 01-15, Volume: 30, Issue:2 IDH1 mutations are closely related to the development and progression of various human cancers, such as glioblastoma, sarcoma, and acute myeloid leukemia. By screening dozens of reported natural compounds using both wild-type and mutant IDH1 enzymatic assays, we discovered Licochalcone A is a selective inhibitor to the R132C-mutant IDH1 with an IC Topics: Cell Line, Tumor; Cell Proliferation; Chalcones; Humans; Isocitrate Dehydrogenase; Sarcoma	2020

Article

Year

Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor.

Bioorganic & medicinal chemistry letters, 2020, 01-15, Volume: 30, Issue:2

IDH1 mutations are closely related to the development and progression of various human cancers, such as glioblastoma, sarcoma, and acute myeloid leukemia. By screening dozens of reported natural compounds using both wild-type and mutant IDH1 enzymatic assays, we discovered Licochalcone A is a selective inhibitor to the R132C-mutant IDH1 with an IC

Topics: Cell Line, Tumor; Cell Proliferation; Chalcones; Humans; Isocitrate Dehydrogenase; Sarcoma

2020