licochalcone-a and Metabolic-Diseases

The main function of brown adipose tissue is to dissipate surplus caloric intake into heat energy by thermogenesis, increasing energy expenditure. Inducible brown adipocytes can develop within white adipose tissue (WAT) through a process referred to as browning. Browning of white fat represents a promising strategy for treatment of obesity and the related complications. We investigated whether Glycyrrhiza uralensis and its ingredients modulated adipogenesis through adipocyte browning using 3T3-L1 adipocytes and a high-fat diet (HFD)-induced obesity mice model. Amongst extracts and fractions of G. uralensis, methyl dichloride (MeCl

Topics: 3T3-L1 Cells; Adipocytes, Brown; Animals; Chalcones; Diet, High-Fat; Disease Models, Animal; Glycyrrhiza uralensis; Injections, Intraperitoneal; Metabolic Diseases; Mice; Obesity; Plant Extracts; Plant Roots