Page last updated: 2024-10-30

lg 100268 and Pancreatic Neoplasms

lg 100268 has been researched along with Pancreatic Neoplasms in 2 studies

LG 100268: a retinoid X receptor (RXR) selective compound; structure given in first source

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
"Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States and is nearly always fatal."1.36Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer. ( Hruban, RH; Liby, KT; Maitra, A; Risingsong, R; Royce, DB; Sporn, MB; Williams, CR, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liby, KT1
Royce, DB1
Risingsong, R1
Williams, CR1
Maitra, A1
Hruban, RH1
Sporn, MB1
Ravnskjaer, K1
Boergesen, M1
Rubi, B1
Larsen, JK1
Nielsen, T1
Fridriksson, J1
Maechler, P1
Mandrup, S1

Other Studies

2 other studies available for lg 100268 and Pancreatic Neoplasms

ArticleYear
Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:11

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Disease Models, Animal; Mice; Mice, Transgenic; N

2010
Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells.
    Endocrinology, 2005, Volume: 146, Issue:8

    Topics: Adenoviridae; Animals; Cell Line, Tumor; DNA Primers; Genes, Reporter; Glucose; Insulin; Insulin Sec

2005