lg 100268 has been researched along with Pancreatic Neoplasms in 2 studies
LG 100268: a retinoid X receptor (RXR) selective compound; structure given in first source
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States and is nearly always fatal." | 1.36 | Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer. ( Hruban, RH; Liby, KT; Maitra, A; Risingsong, R; Royce, DB; Sporn, MB; Williams, CR, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liby, KT | 1 |
| Royce, DB | 1 |
| Risingsong, R | 1 |
| Williams, CR | 1 |
| Maitra, A | 1 |
| Hruban, RH | 1 |
| Sporn, MB | 1 |
| Ravnskjaer, K | 1 |
| Boergesen, M | 1 |
| Rubi, B | 1 |
| Larsen, JK | 1 |
| Nielsen, T | 1 |
| Fridriksson, J | 1 |
| Maechler, P | 1 |
| Mandrup, S | 1 |
2 other studies available for lg 100268 and Pancreatic Neoplasms
| Article | Year |
|---|---|
Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Disease Models, Animal; Mice; Mice, Transgenic; N | 2010 |
Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells.
Topics: Adenoviridae; Animals; Cell Line, Tumor; DNA Primers; Genes, Reporter; Glucose; Insulin; Insulin Sec | 2005 |