lg 100268 has been researched along with Insulin Resistance in 6 studies
LG 100268: a retinoid X receptor (RXR) selective compound; structure given in first source
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
Excerpt | Relevance | Reference |
---|---|---|
"Chronic administration of retinoid X receptor agonists LG 100268 and LG 100324 to Zucker fa/fa rats reduces food intake and body weight gain, lowers plasma insulin concentrations while maintaining normoglycaemia, indicating an improvement of insulin sensitivity." | 3.70 | Retinoid X receptor agonists have anti-obesity effects and improve insulin sensitivity in Zucker fa/fa rats. ( Cawthorne, MA; Crombie, DL; Heyman, RA; Hislop, DC; Liu, YL; Sennitt, MV, 2000) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 5 (83.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Michellys, PY | 1 |
Ardecky, RJ | 1 |
Chen, JH | 1 |
Crombie, DL | 3 |
Etgen, GJ | 1 |
Faul, MM | 1 |
Faulkner, AL | 1 |
Grese, TA | 1 |
Heyman, RA | 4 |
Karanewsky, DS | 1 |
Klausing, K | 2 |
Leibowitz, MD | 2 |
Liu, S | 1 |
Mais, DA | 1 |
Mapes, CM | 1 |
Marschke, KB | 1 |
Reifel-Miller, A | 1 |
Ogilvie, KM | 1 |
Rungta, D | 2 |
Thompson, AW | 1 |
Tyhonas, JS | 1 |
Boehm, MF | 2 |
Mukherjee, R | 1 |
Davies, PJ | 2 |
Bischoff, ED | 1 |
Cesario, RM | 2 |
Jow, L | 1 |
Hamann, LG | 1 |
Mondon, CE | 1 |
Nadzan, AM | 1 |
Paterniti, JR | 1 |
Liu, YL | 1 |
Sennitt, MV | 1 |
Hislop, DC | 1 |
Cawthorne, MA | 1 |
Razzaghi, H | 1 |
Crombie, D | 1 |
Lala, DS | 1 |
Yamauchi, T | 1 |
Waki, H | 1 |
Kamon, J | 1 |
Murakami, K | 1 |
Motojima, K | 1 |
Komeda, K | 1 |
Miki, H | 1 |
Kubota, N | 1 |
Terauchi, Y | 1 |
Tsuchida, A | 1 |
Tsuboyama-Kasaoka, N | 1 |
Yamauchi, N | 1 |
Ide, T | 1 |
Hori, W | 1 |
Kato, S | 1 |
Fukayama, M | 1 |
Akanuma, Y | 1 |
Ezaki, O | 1 |
Itai, A | 1 |
Nagai, R | 1 |
Kimura, S | 1 |
Tobe, K | 1 |
Kagechika, H | 1 |
Shudo, K | 1 |
Kadowaki, T | 1 |
Shen, Q | 1 |
Cline, GW | 1 |
Shulman, GI | 1 |
6 other studies available for lg 100268 and Insulin Resistance
Article | Year |
---|---|
Novel (2E,4E,6Z)-7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic acid retinoid X receptor modulators are active in models of type 2 diabetes.
Topics: Animals; Blood Glucose; Caprylates; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin Resistan | 2003 |
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists.
Topics: Animals; Bexarotene; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Female; Glucose Tole | 1997 |
Retinoid X receptor agonists have anti-obesity effects and improve insulin sensitivity in Zucker fa/fa rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Eating; Hypoglycemic Agents; Insulin; Ins | 2000 |
The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo.
Topics: 3T3 Cells; Adipocytes; Animals; Blood Glucose; Cell Differentiation; Diabetes Mellitus; Dimerization | 2001 |
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
Topics: 3T3 Cells; Adipose Tissue; Animals; Benzhydryl Compounds; Benzoates; Biphenyl Compounds; Diabetes Me | 2001 |
Effects of rexinoids on glucose transport and insulin-mediated signaling in skeletal muscles of diabetic (db/db) mice.
Topics: Acyl Coenzyme A; Animals; Anticholesteremic Agents; Biological Transport; Blotting, Western; Body We | 2004 |