lg 100268 has been researched along with Insulin Resistance in 6 studies
LG 100268: a retinoid X receptor (RXR) selective compound; structure given in first source
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic administration of retinoid X receptor agonists LG 100268 and LG 100324 to Zucker fa/fa rats reduces food intake and body weight gain, lowers plasma insulin concentrations while maintaining normoglycaemia, indicating an improvement of insulin sensitivity." | 3.70 | Retinoid X receptor agonists have anti-obesity effects and improve insulin sensitivity in Zucker fa/fa rats. ( Cawthorne, MA; Crombie, DL; Heyman, RA; Hislop, DC; Liu, YL; Sennitt, MV, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Michellys, PY | 1 |
| Ardecky, RJ | 1 |
| Chen, JH | 1 |
| Crombie, DL | 3 |
| Etgen, GJ | 1 |
| Faul, MM | 1 |
| Faulkner, AL | 1 |
| Grese, TA | 1 |
| Heyman, RA | 4 |
| Karanewsky, DS | 1 |
| Klausing, K | 2 |
| Leibowitz, MD | 2 |
| Liu, S | 1 |
| Mais, DA | 1 |
| Mapes, CM | 1 |
| Marschke, KB | 1 |
| Reifel-Miller, A | 1 |
| Ogilvie, KM | 1 |
| Rungta, D | 2 |
| Thompson, AW | 1 |
| Tyhonas, JS | 1 |
| Boehm, MF | 2 |
| Mukherjee, R | 1 |
| Davies, PJ | 2 |
| Bischoff, ED | 1 |
| Cesario, RM | 2 |
| Jow, L | 1 |
| Hamann, LG | 1 |
| Mondon, CE | 1 |
| Nadzan, AM | 1 |
| Paterniti, JR | 1 |
| Liu, YL | 1 |
| Sennitt, MV | 1 |
| Hislop, DC | 1 |
| Cawthorne, MA | 1 |
| Razzaghi, H | 1 |
| Crombie, D | 1 |
| Lala, DS | 1 |
| Yamauchi, T | 1 |
| Waki, H | 1 |
| Kamon, J | 1 |
| Murakami, K | 1 |
| Motojima, K | 1 |
| Komeda, K | 1 |
| Miki, H | 1 |
| Kubota, N | 1 |
| Terauchi, Y | 1 |
| Tsuchida, A | 1 |
| Tsuboyama-Kasaoka, N | 1 |
| Yamauchi, N | 1 |
| Ide, T | 1 |
| Hori, W | 1 |
| Kato, S | 1 |
| Fukayama, M | 1 |
| Akanuma, Y | 1 |
| Ezaki, O | 1 |
| Itai, A | 1 |
| Nagai, R | 1 |
| Kimura, S | 1 |
| Tobe, K | 1 |
| Kagechika, H | 1 |
| Shudo, K | 1 |
| Kadowaki, T | 1 |
| Shen, Q | 1 |
| Cline, GW | 1 |
| Shulman, GI | 1 |
6 other studies available for lg 100268 and Insulin Resistance
| Article | Year |
|---|---|
Novel (2E,4E,6Z)-7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic acid retinoid X receptor modulators are active in models of type 2 diabetes.
Topics: Animals; Blood Glucose; Caprylates; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin Resistan | 2003 |
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists.
Topics: Animals; Bexarotene; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Female; Glucose Tole | 1997 |
Retinoid X receptor agonists have anti-obesity effects and improve insulin sensitivity in Zucker fa/fa rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Eating; Hypoglycemic Agents; Insulin; Ins | 2000 |
The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo.
Topics: 3T3 Cells; Adipocytes; Animals; Blood Glucose; Cell Differentiation; Diabetes Mellitus; Dimerization | 2001 |
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
Topics: 3T3 Cells; Adipose Tissue; Animals; Benzhydryl Compounds; Benzoates; Biphenyl Compounds; Diabetes Me | 2001 |
Effects of rexinoids on glucose transport and insulin-mediated signaling in skeletal muscles of diabetic (db/db) mice.
Topics: Acyl Coenzyme A; Animals; Anticholesteremic Agents; Biological Transport; Blotting, Western; Body We | 2004 |