lg 100268 has been researched along with Breast Cancer in 5 studies
LG 100268: a retinoid X receptor (RXR) selective compound; structure given in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effects of a nuclear receptor system constituted by retinoid X receptor (RXR) and its heterodimer partner on the aromatase activity in a cultured MCF-7 human breast cancer cell line and also in human ovarian granulosa cells, using each selective ligand for retinoic acid receptor, RAR (TTNPB), retinoid X receptor, RXR (LG100268), PPARgamma (troglitazone), and vitamin D3 receptor (cholecalciferol)." | 3.71 | Regulation of aromatase by nuclear receptors. ( Goto, K; Mu, YM; Nawata, H; Nishi, Y; Nomura, M; Okabe, T; Takayanagi, R; Yanase, T, 2001) |
| "We set out to test several ER-negative breast cancer cell lines for expression of RAR alpha protein and responsiveness to retinoids in growth inhibition assays." | 1.30 | Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status. ( Allegretto, EA; Chandraratna, RA; Fitzgerald, P; Heyman, RA; Teng, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seo, HS | 1 |
| Woo, JK | 1 |
| Shin, YC | 1 |
| Ko, SG | 1 |
| Hede, K | 1 |
| Fitzgerald, P | 1 |
| Teng, M | 1 |
| Chandraratna, RA | 1 |
| Heyman, RA | 1 |
| Allegretto, EA | 1 |
| Mu, YM | 2 |
| Yanase, T | 2 |
| Nishi, Y | 2 |
| Hirase, N | 1 |
| Goto, K | 2 |
| Takayanagi, R | 2 |
| Nawata, H | 2 |
| Nomura, M | 1 |
| Okabe, T | 1 |
5 other studies available for lg 100268 and Breast Cancer
| Article | Year |
|---|---|
Identification of biomarkers regulated by rexinoids (LGD1069, LG100268 and Ro25-7386) in human breast cells using Affymetrix microarray.
Topics: Anticarcinogenic Agents; Bexarotene; Biomarkers, Tumor; Breast; Breast Neoplasms; Cell Proliferation | 2015 |
Rexinoids may be ready for prime time in prevention, but challenges remain.
Topics: Animals; Anticarcinogenic Agents; Bexarotene; Breast Neoplasms; Clinical Trials as Topic; Disease Mo | 2004 |
Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status.
Topics: Alitretinoin; Aminobenzoates; Antineoplastic Agents; Benzoates; Bexarotene; Breast Neoplasms; Cell D | 1997 |
A nuclear receptor system constituted by RAR and RXR induces aromatase activity in MCF-7 human breast cancer cells.
Topics: Aromatase; Base Sequence; Benzoates; Breast Neoplasms; DNA Primers; Enzyme Induction; Estrone; Exons | 2000 |
Regulation of aromatase by nuclear receptors.
Topics: Aromatase; Benzoates; Breast Neoplasms; Cholecalciferol; Chromans; Female; Gene Expression Regulatio | 2001 |