Page last updated: 2024-10-30

lg 100268 and Acute Promyelocytic Leukemia

lg 100268 has been researched along with Acute Promyelocytic Leukemia in 3 studies

LG 100268: a retinoid X receptor (RXR) selective compound; structure given in first source

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boehm, MF1
Zhang, L1
Zhi, L1
McClurg, MR1
Berger, E1
Wagoner, M1
Mais, DE1
Suto, CM1
Davies, JA1
Heyman, RA1
Xu, T1
Zhong, L1
Gan, LG1
Xiao, CL1
Shan, ZL1
Yang, R1
Song, H1
Li, L1
Liu, BZ1
Tabe, Y1
Konopleva, M1
Kondo, Y1
Contractor, R1
Tsao, T1
Konoplev, S1
Shi, Y1
Ling, X1
Watt, JC1
Tsutsumi-Ishii, Y1
Ohsaka, A1
Nagaoka, I1
Issa, JP1
Kogan, SC1
Andreeff, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase I Study of Bexarotene in Patients With Acute Myeloid Leukemia[NCT00316030]Phase 154 participants Interventional2004-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for lg 100268 and Acute Promyelocytic Leukemia

ArticleYear
Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells.
    Journal of medicinal chemistry, 1995, Aug-04, Volume: 38, Issue:16

    Topics: Apoptosis; Bexarotene; Binding, Competitive; Cell Line; Drug Design; Humans; Leukemia, Promyelocytic

1995
Effects of LG268 on Cell Proliferation and Apoptosis of NB4 Cells.
    International journal of medical sciences, 2016, Volume: 13, Issue:7

    Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation,

2016
PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.
    Cancer biology & therapy, 2007, Volume: 6, Issue:12

    Topics: Acetylation; Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Line, Tumor; Drug

2007