lfm-a13 and Inflammation

lfm-a13 has been researched along with Inflammation* in 2 studies

Reviews

1 review(s) available for lfm-a13 and Inflammation

ArticleYear
Bruton's tyrosine kinase inhibitors: approaches to potent and selective inhibition, preclinical and clinical evaluation for inflammatory diseases and B cell malignancies.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Catalytic Domain; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Industry; Humans; Inflammation; Leukemia, B-Cell; Models, Molecular; Protein Conformation; Protein-Tyrosine Kinases; Structure-Activity Relationship

2012

Other Studies

1 other study(ies) available for lfm-a13 and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    This protocol describes microsphere-based protease assays for use in flow cytometry and high-throughput screening. This platform measures a loss of fluorescence from the surface of a microsphere due to the cleavage of an attached fluorescent protease substrate by a suitable protease enzyme. The assay format can be adapted to any site or protein-specific protease of interest and results can be measured in both real time and as endpoint fluorescence assays on a flow cytometer. Endpoint assays are easily adapted to microplate format for flow cytometry high-throughput analysis and inhibitor screening.

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature

2010