levosulpiride and Parkinsonian-Disorders

levosulpiride has been researched along with Parkinsonian-Disorders* in 2 studies

Other Studies

2 other study(ies) available for levosulpiride and Parkinsonian-Disorders

Article	Year
An Unusual Cause of Camptocormia. Tremor and other hyperkinetic movements (New York, N.Y.), 2019, Volume: 9 Camptocormia is defined as forward flexion of the spine that manifests during walking and standing and disappears in recumbent position. The various etiologies include idiopathic Parkinson's disease, multiple system atrophy, myopathies, degenerative joint disease, and drugs.. A 67-year-old diabetic female presented with bradykinesia and camptocormia that started 1 year prior to presentation. Evaluation revealed levosulpiride, a dopamine receptor blocker commonly used for dyspepsia, to be the culprit.. It is well known that dopamine receptor blockers cause parkinsonism and tardive syndromes. We report a rare and unusual presentation of camptocormia attributed to this commonly used gastrointestinal drug in the Asian population. Topics: Aged; Brain; Diabetes Complications; Diagnosis, Differential; Dopamine Antagonists; Dyspepsia; Female; Humans; Muscular Atrophy, Spinal; Parkinsonian Disorders; Spinal Curvatures; Sulpiride	2019
Diabetes mellitus and drug-induced Parkinsonism: a case-control study. Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2 To investigate if diabetes is more common in drug-induced parkinsonism patients. We performed a hospital-based retrospective case-control study on 44 drug-induced parkinsonism (DIP) patients, 177 Parkinson disease patients, and 176 acute stroke patients matched for age and sex who were seen over the same period at the same hospital. The frequency of diabetes, age-at onset and sex were compared between DIP and IPD or acute stroke. Multivariate analysis showed that patients with diabetes are more frequent in DIP compared with IPD (p<0.001, adjusted OR 5.48; 95% CI, 2.52-11.94). The frequency of diabetes in DIP was comparable to that in acute stroke patients (p=0.16, adjusted OR 0.62; 95% CI, 0.32-1.21). These data suggest that diabetes may be a risk factor for DIP. Drugs with dopamine receptor blocking potency should be avoided in elderly with diabetes. Topics: Age of Onset; Aged; Contraindications; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Susceptibility; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Gastroparesis; Humans; Male; Middle Aged; Parkinsonian Disorders; Retrospective Studies; Risk Factors; Sex Distribution; Single-Blind Method; Stroke; Sulpiride	2009

Article

Year

Tremor and other hyperkinetic movements (New York, N.Y.), 2019, Volume: 9

Camptocormia is defined as forward flexion of the spine that manifests during walking and standing and disappears in recumbent position. The various etiologies include idiopathic Parkinson's disease, multiple system atrophy, myopathies, degenerative joint disease, and drugs.. A 67-year-old diabetic female presented with bradykinesia and camptocormia that started 1 year prior to presentation. Evaluation revealed levosulpiride, a dopamine receptor blocker commonly used for dyspepsia, to be the culprit.. It is well known that dopamine receptor blockers cause parkinsonism and tardive syndromes. We report a rare and unusual presentation of camptocormia attributed to this commonly used gastrointestinal drug in the Asian population.

Topics: Aged; Brain; Diabetes Complications; Diagnosis, Differential; Dopamine Antagonists; Dyspepsia; Female; Humans; Muscular Atrophy, Spinal; Parkinsonian Disorders; Spinal Curvatures; Sulpiride

2019

Diabetes mellitus and drug-induced Parkinsonism: a case-control study.

Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2

To investigate if diabetes is more common in drug-induced parkinsonism patients. We performed a hospital-based retrospective case-control study on 44 drug-induced parkinsonism (DIP) patients, 177 Parkinson disease patients, and 176 acute stroke patients matched for age and sex who were seen over the same period at the same hospital. The frequency of diabetes, age-at onset and sex were compared between DIP and IPD or acute stroke. Multivariate analysis showed that patients with diabetes are more frequent in DIP compared with IPD (p<0.001, adjusted OR 5.48; 95% CI, 2.52-11.94). The frequency of diabetes in DIP was comparable to that in acute stroke patients (p=0.16, adjusted OR 0.62; 95% CI, 0.32-1.21). These data suggest that diabetes may be a risk factor for DIP. Drugs with dopamine receptor blocking potency should be avoided in elderly with diabetes.

Topics: Age of Onset; Aged; Contraindications; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Susceptibility; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Gastroparesis; Humans; Male; Middle Aged; Parkinsonian Disorders; Retrospective Studies; Risk Factors; Sex Distribution; Single-Blind Method; Stroke; Sulpiride

2009