levorphanol has been researched along with Brain-Neoplasms* in 1 studies
1 other study(ies) available for levorphanol and Brain-Neoplasms
| Article | Year |
|---|---|
Opioids potentiate transmitter release from SK-N-SH human neuroblastoma cells by modulating N-type calcium channels.
Opioids induce dual (inhibitory and excitatory) regulation of depolarization-evoked [3H]dopamine release in SK-N-SH cells through either mu or delta receptors. The potentiation of dopamine release by opioid agonists is mediated by N-type voltage-dependent calcium channels and does not involve Gi/Go proteins. Removal of the excitatory opioid effect by blockade with omega-conotoxin, an N-channel antagonist, reveals the inhibitory effect of opioids on release, thus suggesting that both modulatory effects of opioids are exerted in parallel. Topics: Brain Neoplasms; Calcium Channel Blockers; Calcium Channels; Dopamine; GTP-Binding Proteins; Humans; Levorphanol; Morphine; Narcotics; Neuroblastoma; Neurotransmitter Agents; Opioid Peptides; Tumor Cells, Cultured | 1997 |