Page last updated: 2024-08-21

levonorgestrel and Activated Protein C Resistance

levonorgestrel has been researched along with Activated Protein C Resistance in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (25.00)	18.2507
2000's	8 (66.67)	29.6817
2010's	1 (8.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Helmerhorst, FM; Rosendaal, FR; Rosing, J; Tchaikovski, SN; van Vliet, HA	1
Duijkers, I; Junge, W; Klipping, C; Mellinger, U; Parke, S; Serrani, M	1
Algra, A; Bouma, BN; Grobbee, DE; Kemmeren, JM; Meijers, JC	2
Bouma, BN; Deguchi, H; Griffin, JH; Lee, YM; Middeldorp, S	1
Bremme, K; Hamsten, A; Hansson, LO; Rosing, J; Silveira, A; Thomassen, S; van Rooijen, M	1
Bertina, RM; Dahm, AE; Helmerhorst, FM; Rosendaal, FR; Rosing, J; Sandset, PM; van Vliet, HA	1
de Maat, MP; Heinemann, LA; Kluft, C; Schramm, W; Spannagl, M	1
Bouma, BN; Büller, HR; Christella, M; Curvers, J; Meijers, JC; Middeldorp, S; Nicolaes, GA; Prins, MH; Rosing, J; Tans, G; Thomassen, LG	1
Koh, SC; Prasad, RN; Ratnam, SS; Viegas, OA	1
Kluft, C	1
Bouma, BN; Büller, HR; Curvers, J; Meijers, JC; Middeldorp, S; Prins, MH; Rosing, J; Tans, G; Thomassen, MC	1

Trials

9 trial(s) available for levonorgestrel and Activated Protein C Resistance

Article	Year
The effect of the levonorgestrel-releasing intrauterine system on the resistance to activated protein C (APC). Thrombosis and haemostasis, 2009, Volume: 101, Issue:4 Topics: Activated Protein C Resistance; Adult; Biomarkers; Contraceptives, Oral, Combined; Female; Genetic Predisposition to Disease; Humans; Intrauterine Devices, Copper; Intrauterine Devices, Medicated; Levonorgestrel; Middle Aged; Pedigree; Risk Assessment; Risk Factors; Thrombin; Time Factors; Venous Thrombosis; Young Adult	2009
Hemostatic effects of a novel estradiol-based oral contraceptive: an open-label, randomized, crossover study of estradiol valerate/dienogest versus ethinylestradiol/levonorgestrel. Drugs in R&D, 2011, Volume: 11, Issue:2 Topics: Activated Protein C Resistance; Adolescent; Adult; Antigens; Antithrombin III; Blood Pressure; Contraceptives, Oral, Hormonal; Cross-Over Studies; Drug Combinations; Estradiol; Ethinyl Estradiol; Factor VII; Factor VIII; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Hemostasis; Humans; Levonorgestrel; Middle Aged; Nandrolone; Patient Compliance; Peptide Fragments; Protein C; Protein Precursors; Protein S; Prothrombin; Sex Hormone-Binding Globulin; Young Adult	2011
Effect of second- and third-generation oral contraceptives on fibrinolysis in the absence or presence of the factor V Leiden mutation. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2002, Volume: 13, Issue:5 Topics: Activated Protein C Resistance; Adult; Carboxypeptidase B2; Contraceptives, Oral, Hormonal; Desogestrel; Double-Blind Method; Ethinyl Estradiol; Factor V; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Humans; Levonorgestrel; Thrombophilia	2002
Decreased plasma sensitivity to activated protein C by oral contraceptives is associated with decreases in plasma glucosylceramide. Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:5 Topics: Activated Protein C Resistance; Chromatography, High Pressure Liquid; Contraceptives, Oral; Contraceptives, Oral, Combined; Desogestrel; Estradiol; Ethinyl Estradiol; Female; Glucosylceramides; Humans; Levonorgestrel; Pilot Projects; Protein C; Protein S; Prothrombin Time; Risk; Sensitivity and Specificity; Venous Thrombosis	2005
Rapid activation of haemostasis after hormonal emergency contraception. Thrombosis and haemostasis, 2007, Volume: 97, Issue:1 Topics: Activated Protein C Resistance; Adult; Apolipoprotein A-I; Apolipoproteins B; Biomarkers; Blood Coagulation; Contraceptives, Oral, Hormonal; Cross-Over Studies; Drug Therapy, Combination; Estrogens; Female; Hemostasis; Humans; Levonorgestrel; Liver	2007
Low-dose oral contraceptives and acquired resistance to activated protein C: a randomised cross-over study. Lancet (London, England), 1999, Dec-11, Volume: 354, Issue:9195 Topics: Activated Protein C Resistance; Adolescent; Adult; Contraceptives, Oral, Synthetic; Cross-Over Studies; Desogestrel; Dose-Response Relationship, Drug; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Protein C; Risk Factors; Thrombin; Thromboembolism	1999
Effects on hemostasis after two-year use of low dose combined oral contraceptives with gestodene or levonorgestrel. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 1999, Volume: 5, Issue:1 Topics: Activated Protein C Resistance; Adolescent; Adult; Analysis of Variance; Antigens; Antithrombin III; beta-Thromboglobulin; Blood Platelets; Contraceptives, Oral, Synthetic; Factor VII; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Hematocrit; Hemoglobins; Hemostasis; Humans; Levonorgestrel; Norpregnenes; Partial Thromboplastin Time; Peptide Fragments; Peptide Hydrolases; Plasminogen; Progesterone Congeners; Protein C; Protein S; Prothrombin; Thrombelastography; Time Factors; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator; von Willebrand Factor	1999
A randomized cross-over study on the effects of levonorgestrel- and desogestrel-containing oral contraceptives on the anticoagulant pathways. Thrombosis and haemostasis, 2000, Volume: 84, Issue:1 Topics: Activated Protein C Resistance; Adolescent; Adult; alpha 1-Antitrypsin; alpha-Macroglobulins; Antithrombins; Biomarkers; Blood Coagulation; Blood Proteins; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Cross-Over Studies; Desogestrel; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Netherlands; Partial Thromboplastin Time; Protein C; Protein C Inhibitor; Protein S; Thrombin; Thrombophilia	2000
Effects of second and third generation oral contraceptives and their respective progestagens on the coagulation system in the absence or presence of the factor V Leiden mutation. Thrombosis and haemostasis, 2002, Volume: 87, Issue:2 Topics: Activated Protein C Resistance; Adult; Blood Coagulation; Blood Coagulation Factors; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Desogestrel; Double-Blind Method; Ethinyl Estradiol; Factor IX; Factor V; Factor VII; Female; Humans; Levonorgestrel; Peptide Fragments; Prothrombin; Thrombophilia	2002

Other Studies

3 other study(ies) available for levonorgestrel and Activated Protein C Resistance

Article	Year
Different effects of oral contraceptives containing different progestogens on protein S and tissue factor pathway inhibitor. Journal of thrombosis and haemostasis : JTH, 2008, Volume: 6, Issue:2 Topics: Activated Protein C Resistance; Adolescent; Adult; Androstenes; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Contraceptives, Oral, Synthetic; Cyproterone Acetate; Desogestrel; Ethinyl Estradiol-Norgestrel Combination; Female; Humans; Levonorgestrel; Lipoproteins; Middle Aged; Protein S; Thrombophilia	2008
Importance of levonorgestrel dose in oral contraceptives for effects on coagulation. Lancet (London, England), 1999, Sep-04, Volume: 354, Issue:9181 Topics: Activated Protein C Resistance; Blood Coagulation; Contraceptives, Oral, Combined; Contraceptives, Oral, Synthetic; Female; Humans; Levonorgestrel	1999
Renewed interest in haemostasis changes induced by oral contraceptives (OCs) Thrombosis and haemostasis, 2000, Volume: 84, Issue:1 Topics: Activated Protein C Resistance; Adult; Biomarkers; Blood Coagulation Factors; Blood Proteins; Case-Control Studies; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Cross-Over Studies; Desogestrel; Ethinyl Estradiol; Female; Genetic Predisposition to Disease; Hemostasis; Humans; Levonorgestrel; Partial Thromboplastin Time; Randomized Controlled Trials as Topic; Thrombophilia; Venous Thrombosis	2000