levoleucovorin and Retinal-Vasculitis

To describe a case of recurrent frosted branch angiitis after treatment of ocular toxoplasmosis.. In a 6-year-old boy, we found perivascular, creamy, patchy, retinal sheathing in both eyes without any focal necrotizing retinochoroiditis or scarring. IgM antibodies for toxoplasma gondii were also found. The patient was treated with antitoxoplasmosis medication and a systemic steroid.. Several years after treatment of the toxoplasmosis, frosted branch angiitis occurred twice without any retinal scarring or serological evidence of toxoplasmosis. After systemic steroid therapy, the angiitis improved without further complications.. Toxoplasmic retinal vasculitis should be considered as a cause of frosted branch angiitis.

Topics: Antiprotozoal Agents; Child; Chorioretinitis; Drug Therapy, Combination; Fluorescein Angiography; Glucocorticoids; Humans; Leucovorin; Male; Pyrimethamine; Recurrence; Retinal Vasculitis; Toxoplasmosis, Ocular