Page last updated: 2024-09-04

levofloxacin and Pneumonia, Pneumococcal

levofloxacin has been researched along with Pneumonia, Pneumococcal in 46 studies

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (8.70)	18.2507
2000's	30 (65.22)	29.6817
2010's	12 (26.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Duncan, LR; Flamm, RK; Mendes, RE; Pfaller, MA; Sader, HS	1
Cho, SY; Chung, DR; Ha, YE; Huh, K; Kang, CI; Peck, KR; Seok, H	1
Esteban, J; Fernández-Guerrero, ML; Fernández-Roblas, R; Isea-Peña, MC; Sanz-Moreno, JC	1
Chung, DR; Hsueh, PR; Kang, CI; Kim, SH; Peck, KR; So, TM; Song, JH	1
Adhikary, R; Bhattacharyya, A; Bishayi, B; Mahanti, S; Majhi, A	1
Cabrera, A; Domenech, N; Hernández Bel, L; Moratal E Cervera, B	1
Courter, JD; Girotto, JE; Kazazian, C; Nichols, KR	1
Chen, HH; Chiu, CH; Li, HC; Su, LH	1
Hirai, J; Koizumi, Y; Mikamo, H; Nishiyama, N; Sakanashi, D; Suematsu, H; Sugimoto, N; Yamagishi, Y	1
Cheng, VC; Chow, KH; Ho, PL	1
Chang, LY; Hsieh, YC; Hsueh, PR; Huang, LM; Huang, YC; Lin, HC	1
Cao, GY; Huang, JA; Liu, YB; Shi, YG; Si, B; Sun, SH; Wu, XJ; Xia, QM; Xiao, ZK; Xu, JF; Zhang, J; Zhang, YY	1
Araj, GF; Awar, GN; Baban, TA; Kanj, SS; Naba, MR; Tabbarah, ZA	1
Bijlsma, JJ; Canton, E; Gant, CM; González-Morán, F; López-Hontangas, JL; Rosingh, AW; van der Heijden, M	1
Ahanou, A; Buisson, M; Chavanet, P; Croisier, D; Duong, M; Lequeu, C; Neuwirth, C; Nierlich, A; Piroth, L; Portier, H	1
Rubinstein, E	1
Aguilar, L; García-Calvo, G; García-Olmos, M; Giménez, MJ; Parra, A; Ponte, C; Soriano, F	1
Anderson, KB; DiPersio, JR; File, TM; Low, DE; Tan, JS; Willey, BM	1
Fraschini, F; Mattina, R; Mouton, JW; Scaglione, F	1
Alfandari, S; d'Escrivan, T; Guery, B; Roussel-Delvallez, M	1
Bergoin, E; Charles, PE; Chavanet, P; Croisier, D; Etienne, M; Lequeu, C; Piroth, L; Portier, H	1
Low, DE	1
Fukuda, Y; Hirakata, Y; Kadota, J; Kohno, S; Miyazaki, Y; Murata, I; Tashiro, T; Tomono, K; Tsukamoto, K; Yanagihara, K	1
Bast, DJ; Bell, D; Chen, X; de Azavedo, JC; Dresser, L; Low, DE; Mandell, LA; Saskin, R; Yue, M	1
Zubkov, MN	1
Aguado, JM; Carlavilla, AB; Chaves, F; Echave-Sustaeta, J; López-Medrano, F; Villena, V	1
Fritsche, TR; Jones, RN; Sader, HS	1
Bettaccini, AA; Brigante, G; Endimiani, A; Grossi, P; Luzzaro, F; Toniolo, AQ	1
Carratalá, J; García-Rey, C; Martín-Herrero, JE; Mykietiuk, A	1
Aguilar, L; Alou, L; Cafini, F; Echeverría, O; Giménez, MJ; Pérez-Trallero, E; Prieto, J; Sevillano, D	1
Bast, DJ; de Azavedo, JC; Dresser, L; Duncan, CL; Low, DE; Mandell, LA; Walker, SE	1
de Cueto, M; López-Cerero, L; Pascual, A; Rodríguez, JM; Soriano, MJ; Venero, J	1
Alsina, M; Calbo, E; Garau, J; Lite, J; Rodríguez-Carballeira, M	1
Geweniger, KH; Isert, D; Iyer, P; Klesel, N; Koletzki, P; Limbert, M; Markus, A; Riess, G; Schramm, H	1
Bryskier, A; Lemperle, M; Lütticken, R; Reinert, RR	1
Amsden, GW; Cabelus, LJ; Graci, DM; Hejmanowski, LG	1
Léophonte, P; Veyssier, P	1
Bush, K; Fogarty, C; Goldschmidt, R	1
Shah, PM	1
Dunbar, L; Fogarty, CM; Greenberg, RN; Kojak, CM; Marrie, TJ; Morgan, N; Player, R; Williams, RR	1
Empey, PE; Evans, ME; Jennings, HR; Rapp, RP; Thornton, AC	1
Drlica, K; Mariano, N; Rahal, JJ; Rahman, N; Segal-Maurer, S; Urban, C; Zhao, X	1
Bast, DJ; Brunton, JL; Cavalcanti, R; Davidson, R; de Azavedo, JC; Fleming, C; Kibsey, P; Low, DE	1
Denys, GA; Kays, MB; Smith, DW; Wack, ME	1
Gorbach, SL; Ross, JJ; Worthington, MG	1
Chan, CK; Hoban, DJ; Zhanel, GG	1

Reviews

4 review(s) available for levofloxacin and Pneumonia, Pneumococcal

Article	Year
Invasive pneumococcal disease caused by mucoid serotype 3 Streptococcus pneumoniae: a case report and literature review. BMC research notes, 2017, Jan-04, Volume: 10, Issue:1 Topics: Aged; Anti-Bacterial Agents; Carbapenems; Cephalosporins; Erythromycin; Hospitalization; Humans; Japan; Levofloxacin; Male; Microbial Sensitivity Tests; Penicillins; Pneumonia, Pneumococcal; Serogroup; Serotyping; Streptococcus pneumoniae; Treatment Outcome	2017
[Efficacy and safety of levofloxacin in low respiratory tract infection]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2004, Volume: 49, Issue:5 Topics: Anti-Bacterial Agents; Central Nervous System Diseases; Clinical Trials as Topic; Dermatitis, Atopic; Gastrointestinal Diseases; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Respiratory Tract Infections; Streptococcus pneumoniae	2004
Clinical experience in the management of community-acquired pneumonia: lessons from the use of fluoroquinolones. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2006, Volume: 12 Suppl 3 Topics: Adult; Anti-Bacterial Agents; Clinical Trials as Topic; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2006
The use of levofloxacin in the treatment of respiratory tract infection. Journal of chemotherapy (Florence, Italy), 2000, Volume: 12 Suppl 4 Topics: Anti-Infective Agents; Bronchitis; Chronic Disease; Community-Acquired Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial; Pneumonia, Pneumococcal; Respiratory Tract Infections; Streptococcus pneumoniae	2000

Trials

5 trial(s) available for levofloxacin and Pneumonia, Pneumococcal

Article	Year
Population pharmacokinetics of oral levofloxacin 500 mg once-daily dosage in community-acquired lower respiratory tract infections: results of a prospective multicenter study in China. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2009, Volume: 15, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bronchitis, Chronic; China; Community-Acquired Infections; Creatinine; Drug Administration Schedule; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Prospective Studies; Recurrence	2009
Systemic expression of cytokine production in patients with severe pneumococcal pneumonia: effects of treatment with a beta-lactam versus a fluoroquinolone. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ceftriaxone; Cytokines; Female; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukins; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Prospective Studies; Time Factors; Tumor Necrosis Factor-alpha	2008
A randomized, crossover design study of the pharmacology of extended-spectrum fluoroquinolones for pneumococcal infections. Chest, 1999, Volume: 116, Issue:1 Topics: Adult; Anti-Infective Agents; Cross-Over Studies; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Prodrugs; Streptococcus pneumoniae	1999
[Levofloxacin in the treatment of community-acquired pneumococcal pneumonia]. Presse medicale (Paris, France : 1983), 1999, Nov-20, Volume: 28, Issue:36 Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents; Ceftriaxone; Cefuroxime; Clavulanic Acid; Community-Acquired Infections; Drug Therapy, Combination; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal	1999
Effectiveness of levofloxacin for adult community-acquired pneumonia caused by macrolide-resistant Streptococcus pneumoniae: integrated results from four open-label, multicenter, phase III clinical trials. Clinical therapeutics, 2001, Volume: 23, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Community-Acquired Infections; Drug Resistance, Microbial; Erythromycin; Humans; Levofloxacin; Ofloxacin; Pneumonia, Pneumococcal	2001

Other Studies

37 other study(ies) available for levofloxacin and Pneumonia, Pneumococcal

Article	Year
Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:2 Topics: Academic Medical Centers; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Drug Resistance, Multiple, Bacterial; Epidemiological Monitoring; Humans; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Tigecycline; United States	2018
Risk Factors for Community-Onset Pneumonia Caused by Levofloxacin-Nonsusceptible Streptococcus pneumoniae. Microbial drug resistance (Larchmont, N.Y.), 2018, Volume: 24, Issue:9 Topics: Aged; Anti-Bacterial Agents; Case-Control Studies; Community-Acquired Infections; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Pneumonia, Pneumococcal; Retrospective Studies; Risk Factors; Streptococcus pneumoniae	2018
Risk factors and clinical significance of invasive infections caused by levofloxacin-resistant Streptococcus pneumoniae. Infection, 2013, Volume: 41, Issue:5 Topics: Anti-Bacterial Agents; Chi-Square Distribution; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Pneumonia, Pneumococcal; Retrospective Studies; Risk Factors; Streptococcus pneumoniae	2013
Risk factors for levofloxacin-nonsusceptible Streptococcus pneumoniae in community-acquired pneumococcal pneumonia: a nested case-control study. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2014, Volume: 33, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactam Resistance; Case-Control Studies; Community-Acquired Infections; Female; Hong Kong; Humans; Korea; Levofloxacin; Male; Middle Aged; Pneumonia, Pneumococcal; Prospective Studies; Risk Factors; Streptococcus pneumoniae; Taiwan; Young Adult	2014
Levofloxacin-ceftriaxone combination attenuates lung inflammation in a mouse model of bacteremic pneumonia caused by multidrug-resistant Streptococcus pneumoniae via inhibition of cytolytic activities of pneumolysin and autolysin. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:9 Topics: Animals; Anti-Bacterial Agents; Bacteremia; Bacterial Proteins; Bronchoalveolar Lavage Fluid; Ceftriaxone; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Levofloxacin; Male; Mice; Mice, Inbred BALB C; N-Acetylmuramoyl-L-alanine Amidase; Pneumococcal Infections; Pneumonia; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Streptolysins; Virulence; Virulence Factors	2014
[Retinal folds as a non-reported secondary effect of darunavir in a 20 year-old HIV patient]. Archivos de la Sociedad Espanola de Oftalmologia, 2015, Volume: 90, Issue:9 Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Darunavir; Female; HIV Infections; HIV Protease Inhibitors; Humans; Levofloxacin; Meropenem; Ophthalmoscopy; Pneumonia, Pneumococcal; Polypharmacy; Retinal Dystrophies; Thienamycins; Young Adult	2015
Pharmacodynamically Guided Levofloxacin Dosing for Pediatric Community-Acquired Pneumonia. Journal of the Pediatric Infectious Diseases Society, 2017, Jun-01, Volume: 6, Issue:2 Topics: Adolescent; Age Factors; Anti-Bacterial Agents; Child; Child, Preschool; Community-Acquired Infections; Dose-Response Relationship, Drug; Humans; Infant; Levofloxacin; Microbial Sensitivity Tests; Monte Carlo Method; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2017
Fluoroquinolone-nonsusceptible Streptococcus pneumoniae isolates from a medical center in the pneumococcal conjugate vaccine era. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2017, Volume: 50, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Disk Diffusion Antimicrobial Tests; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroquinolones; Heptavalent Pneumococcal Conjugate Vaccine; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Multilocus Sequence Typing; Pneumonia, Pneumococcal; Prospective Studies; Serogroup; Streptococcus pneumoniae; Topoisomerase II Inhibitors; Vaccines, Conjugate; Young Adult	2017
Decreasing prevalence of levofloxacin-resistant Streptococcus pneumoniae in Hong Kong, 2001 to 2007. The Journal of antimicrobial chemotherapy, 2009, Volume: 63, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Resistance, Bacterial; Hong Kong; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Prevalence; Streptococcus pneumoniae; Young Adult	2009
Circulation of international clones of levofloxacin non-susceptible Streptococcus pneumoniae in Taiwan. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2010, Volume: 16, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Anti-Bacterial Agents; Base Sequence; Child; Child, Preschool; Community-Acquired Infections; DNA Gyrase; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Epidemiology; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Polymerase Chain Reaction; Risk Factors; Sequence Analysis, Protein; Serotyping; Streptococcus pneumoniae; Taiwan; Young Adult	2010
Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in Lebanon: a report of three cases. Journal of infection and public health, 2010, Volume: 3, Issue:3 Topics: Aged; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Clarithromycin; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Lebanon; Levofloxacin; Male; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Vancomycin	2010
Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:9 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Erythromycin; Humans; Levofloxacin; Ofloxacin; Penicillins; Pneumococcal Vaccines; Pneumonia, Pneumococcal; Serotyping; Spain; Streptococcus pneumoniae; Vaccines, Conjugate	2012
Efficacy and pharmacodynamics of simulated human-like treatment with levofloxacin on experimental pneumonia induced with penicillin-resistant pneumococci with various susceptibilities to fluoroquinolones. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:3 Topics: Animals; Anti-Infective Agents; Area Under Curve; Disease Models, Animal; Genotype; Humans; Levofloxacin; Lung; Male; Microbial Sensitivity Tests; Mutation; Ofloxacin; Penicillin Resistance; Pneumonia, Pneumococcal; Pulmonary Edema; Rabbits; Spleen; Streptococcus pneumoniae	2002
Reply to: Efficacy and pharmacodynamics of simulated human-like treatment with levofloxacin on experimental pneumonia induced with penicillin-resistant pneumococci with various susceptibilities to fluoroquinolones. The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:5 Topics: Animals; Anti-Infective Agents; Disease Models, Animal; Levofloxacin; Ofloxacin; Penicillin Resistance; Pneumonia, Pneumococcal; Quinolones; Rabbits; Streptococcus pneumoniae	2003
Efficacy and pharmacodynamics of gemifloxacin versus levofloxacin in guinea pig pneumococcal pneumonia induced by strains with decreased ciprofloxacin susceptibility. International journal of antimicrobial agents, 2003, Volume: 21, Issue:6 Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Guinea Pigs; Levofloxacin; Lung; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Survival Analysis	2003
Emergence of levofloxacin-resistant pneumococci in immunocompromised adults after therapy for community-acquired pneumonia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Aug-01, Volume: 37, Issue:3 Topics: Adult; Anti-Infective Agents; Community-Acquired Infections; Drug Resistance, Microbial; Humans; Immunocompromised Host; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2003
Pharmacodynamics of levofloxacin and ciprofloxacin in a murine pneumonia model: peak concentration/MIC versus area under the curve/MIC ratios. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:9 Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Colony Count, Microbial; Dose-Response Relationship, Drug; Female; Levofloxacin; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Protein Binding; Streptococcus pneumoniae; Survival Analysis	2003
High level of resistance to levofloxacin of Streptococcus pneumoniae following fluoroquinolone therapy. Infection, 2003, Volume: 31, Issue:5 Topics: Aged; Cefotaxime; Community-Acquired Infections; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Follow-Up Studies; Humans; Infusions, Intravenous; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Risk Assessment; Severity of Illness Index; Streptococcus pneumoniae; Treatment Outcome	2003
Mutant selection window in levofloxacin and moxifloxacin treatments of experimental pneumococcal pneumonia in a rabbit model of human therapy. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:5 Topics: Animals; Anti-Infective Agents; Area Under Curve; Aza Compounds; Colony Count, Microbial; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Lung; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Pneumonia, Pneumococcal; Quinolines; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Spleen; Streptococcus pneumoniae	2004
Quinolone resistance among pneumococci: therapeutic and diagnostic implications. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, May-15, Volume: 38 Suppl 4 Topics: Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2004
Pharmacodynamics and bactericidal activity of gatifloxacin in experimental pneumonia caused by penicillin-resistant Streptococcus pneumoniae. Chemotherapy, 2004, Volume: 50, Issue:3 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gatifloxacin; Levofloxacin; Lung; Mice; Mice, Inbred CBA; Ofloxacin; Penicillin Resistance; Pneumonia, Pneumococcal; Survival Rate	2004
Novel murine model of pneumococcal pneumonia: use of temperature as a measure of disease severity to compare the efficacies of moxifloxacin and levofloxacin. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:9 Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Body Temperature; Colony Count, Microbial; Disease Models, Animal; Female; Fluoroquinolones; Levofloxacin; Lung; Mice; Moxifloxacin; Ofloxacin; Pneumonia, Pneumococcal; Quinolines; Skin Temperature	2004
[Failure of levofloxacin therapy in two cases of community-acquired pneumonia caused by fluoroquinolone-resistant Streptococcus pneumoniae and complicated with empyema]. Enfermedades infecciosas y microbiologia clinica, 2005, Volume: 23, Issue:5 Topics: Aged; Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2005
Therapeutic options among broad-spectrum beta-lactams for infections caused by levofloxacin-nonsusceptible Streptococcus pneumoniae. Diagnostic microbiology and infectious disease, 2005, Volume: 52, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Community-Acquired Infections; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Polymerase Chain Reaction; Respiratory Tract Infections; Streptococcus pneumoniae	2005
Failure of levofloxacin treatment in community-acquired pneumococcal pneumonia. BMC infectious diseases, 2005, Nov-24, Volume: 5 Topics: Aged; Anti-Bacterial Agents; Bacterial Proteins; Community-Acquired Infections; DNA Topoisomerases, Type II; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Ofloxacin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Streptolysins; Treatment Failure	2005
A pharmacodynamic approach to antimicrobial activity in serum and epithelial lining fluid against in vivo-selected Streptococcus pneumoniae mutants and association with clinical failure in pneumonia. The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:2 Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Community-Acquired Infections; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Mutation; Ofloxacin; Pneumonia, Pneumococcal; Quinolines; Serum Bactericidal Test; Streptococcus pneumoniae	2006
Short-course therapy of gemifloxacin effective against pneumococcal pneumonia in mice. Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:6 Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Body Temperature; Colony Count, Microbial; Disease Models, Animal; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Lung; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Mutation, Missense; Naphthyridines; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Survival Analysis; Survival Rate; Time Factors; Treatment Outcome	2006
Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC mutation. Journal of clinical microbiology, 2008, Volume: 46, Issue:4 Topics: Aged; Anti-Bacterial Agents; Bacteremia; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fatal Outcome; Humans; Levofloxacin; Male; Mutation; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure	2008
Chemotherapeutic activity of levofloxacin (HR 355, DR-3355) against systemic and localized infections in laboratory animals. The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:6 Topics: Abscess; Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Female; Granuloma; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Male; Mice; Mice, Inbred C3H; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Pyelonephritis; Rats; Rats, Wistar; Sepsis; Stereoisomerism; Streptococcus pneumoniae	1995
A comparative study of the in-vitro activity of levofloxacin against Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 1999, Volume: 43 Suppl C Topics: Anti-Bacterial Agents; Anti-Infective Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Pneumonia, Pneumococcal; Streptococcus pneumoniae	1999
Bacteremic pneumonia due to multidrug-resistant pneumococci in 3 patients treated unsuccessfully with azithromycin and successfully with levofloxacin. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 31, Issue:2 Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteremia; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2000
Levofloxacin failure in a patient with pneumococcal pneumonia. The Annals of pharmacotherapy, 2001, Volume: 35, Issue:6 Topics: Anti-Infective Agents; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Penicillins; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure	2001
Fluoroquinolone-resistant Streptococcus pneumoniae associated with levofloxacin therapy. The Journal of infectious diseases, 2001, Sep-15, Volume: 184, Issue:6 Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Point Mutation; Streptococcus pneumoniae	2001
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. The New England journal of medicine, 2002, Mar-07, Volume: 346, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Drug Resistance, Bacterial; Fatal Outcome; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure	2002
Levofloxacin treatment failure in a patient with fluoroquinolone-resistant Streptococcus pneumoniae pneumonia. Pharmacotherapy, 2002, Volume: 22, Issue:3 Topics: Anti-Infective Agents; Colony Count, Microbial; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance; Drug Resistance, Microbial; Humans; Levofloxacin; Male; Middle Aged; Mutation; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure	2002
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. The New England journal of medicine, 2002, Jul-04, Volume: 347, Issue:1 Topics: Aged; Anti-Infective Agents; Bacteremia; Drug Resistance, Bacterial; Fatal Outcome; Humans; Levofloxacin; Male; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure	2002
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. The New England journal of medicine, 2002, Jul-04, Volume: 347, Issue:1 Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2002