Page last updated: 2024-09-04

levofloxacin and Long QT Syndrome

levofloxacin has been researched along with Long QT Syndrome in 23 studies

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (4.35)	18.2507
2000's	7 (30.43)	29.6817
2010's	10 (43.48)	24.3611
2020's	5 (21.74)	2.80

Authors

Authors	Studies
Gao, J; Gao, M; Li, L; Liu, F; Liu, Y; Pang, Y; Shu, W; Sun, Y; Xie, L; Zhang, L	1
Fu, A; Gao, A; Guo, D; Guo, H; Li, C; Li, P; Lu, J; Zhao, P	1
Cole, ST; Djumanov, D; Ferber, G; Fernandes, S; Prasad, K; Rosano, G; Sugiyama, A; Täubel, J; Van Langenhoven, L; Wibberley, H	1
Khajavian, S; Moradi, F; Rajabian, M; Ruzbahani, M; Shahbazi, F; Shahsavari, S; Shojaei, L; Tamasoki, N	1
Akbulut Koyuncu, İM; Kızıltunç, E; Uğurlu Ilgın, B	1
Groo, VL; Sadr, R; Tilton, JJ	1
Chen, JC; Kuo, CW; Lin, CC; Tsai, LH; Weng, YM	1
Bennett, CL; Jacob, S; Li, M; Lu, ZK; Rao, GA; Sutton, SS; Yuan, J	1
Diehl, NN; Getz, TW; Heckman, MG; Mentel, JJ; Pagan, RJ; Palmer, WC; Racho, RG; Ray, JC; Sears, SP; Seeger, KM; Serra-Valentin, NA; Snipelisky, DF; Stancampiano, FF	1
Al-Zaiti, SS; Carey, MG; Kozik, TM; Pelter, MM	1
Birkhoff, W; Burggraaf, J; Danhof, M; Gotta, V; Kamerling, I; Kervezee, L; Meijer, JH; Stevens, J	1
Garnett, C; Johannesen, L	1
Ferber, G; Fernandes, S; Täubel, J	1
Foulon, V; Spriet, I; Vandael, E; Vandenberghe, J; Vandenberk, B; Willems, R	1
Estes, LL; Wilson, JW; Zeuli, JD	1
Chien, S; Goodman, DB; Natarajan, J; Noel, GJ; Padmanabhan, M; Solanki, B	1
Blackmon, CL; Nykamp, DL; Roberson, AG; Schmidt, PE	1
Byrns, K; Goldner, B; Makaryus, AN; Makaryus, MN; Natarajan, U; Singer, C	1
Cox, CD; Meyerrose, GE; Peeters, MJ; Seifert, CF; Tsikouris, JP	1
Kawai, H; Komiya, M; Matsumoto, T; Nakayasu, T; Shimada, J; Yamaguchi, H; Yokoyama, H	1
Samaha, FF	1
Chiba, K; Hashimoto, K; Satoh, Y; Shiina, H; Sugiyama, A	1

Reviews

2 review(s) available for levofloxacin and Long QT Syndrome

Article	Year
Cardiac risks associated with antibiotics: azithromycin and levofloxacin. Expert opinion on drug safety, 2015, Volume: 14, Issue:2 Topics: Anti-Bacterial Agents; Azithromycin; Death; Humans; Levofloxacin; Long QT Syndrome	2015
Commentary on: "Levofloxacin-Induced QTc Prolongation Depends on the Time of Drug Administration". CPT: pharmacometrics & systems pharmacology, 2016, Volume: 5, Issue:9 Topics: Animals; Arrhythmias, Cardiac; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Levofloxacin; Long QT Syndrome	2016

Trials

3 trial(s) available for levofloxacin and Long QT Syndrome

Article	Year
Effects of the Fluoroquinolones Moxifloxacin and Levofloxacin on the QT Subintervals: Sex Differences in Ventricular Repolarization. Journal of clinical pharmacology, 2020, Volume: 60, Issue:3 Topics: Action Potentials; Adult; Algorithms; Anti-Bacterial Agents; Calcium Channels; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Gonadal Steroid Hormones; Healthy Volunteers; Heart; Humans; Levofloxacin; Long QT Syndrome; Male; Moxifloxacin; Potassium Channels; Retrospective Studies; Sex Characteristics	2020
Measuring the effects of supratherapeutic doses of levofloxacin on healthy volunteers using four methods of QT correction and periodic and continuous ECG recordings. Journal of clinical pharmacology, 2004, Volume: 44, Issue:5 Topics: Administration, Oral; Adult; Aged; Area Under Curve; Cross-Over Studies; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography, Ambulatory; Female; Heart Conduction System; Heart Rate; Humans; Levofloxacin; Linear Models; Long QT Syndrome; Male; Middle Aged; Myocardial Contraction; Ofloxacin; Syncope; Tachycardia; Time Factors	2004
Effects of three fluoroquinolones on QT analysis after standard treatment courses. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2006, Volume: 11, Issue:1 Topics: Analysis of Variance; Aza Compounds; Ciprofloxacin; Cross-Over Studies; Electrocardiography; Female; Fluoroquinolones; Heart Rate; Humans; Levofloxacin; Long QT Syndrome; Male; Moxifloxacin; Ofloxacin; Quinolines; Statistics, Nonparametric; Torsades de Pointes	2006

Other Studies

18 other study(ies) available for levofloxacin and Long QT Syndrome

Article	Year
Development and Validation of a Nomogram for Prediction of QT Interval Prolongation in Patients Administered Bedaquiline-Containing Regimens in China: a Modeling Study. Antimicrobial agents and chemotherapy, 2022, 09-20, Volume: 66, Issue:9 Topics: Antitubercular Agents; Clofazimine; Creatinine; Diarylquinolines; Humans; Levofloxacin; Long QT Syndrome; Moxifloxacin; Nomograms; Tuberculosis, Multidrug-Resistant	2022
Analysis of clinical characteristics and automatic monitoring of drug-induced arrhythmias in 167,546 inpatients. European journal of clinical pharmacology, 2023, Volume: 79, Issue:6 Topics: Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Inpatients; Levofloxacin; Long QT Syndrome; Male; Retrospective Studies; Risk Factors	2023
Analysis of QTc Interval during Levofloxacin Prescription in Cardiac Patients with Pneumonia. Current drug safety, 2020, Volume: 15, Issue:2 Topics: Adult; Aged; Cross-Sectional Studies; Electrocardiography; Female; Humans; Levofloxacin; Long QT Syndrome; Male; Middle Aged; Pneumonia; Torsades de Pointes	2020
Effect of triple antimicrobial therapy on electrocardiography parameters in patients with mild-to-moderate coronavirus disease 2019. Anatolian journal of cardiology, 2021, Volume: 25, Issue:3 Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hydroxychloroquine; Levofloxacin; Long QT Syndrome; Male; Middle Aged; Oseltamivir; Retrospective Studies; SARS-CoV-2; Severity of Illness Index; Treatment Outcome; Young Adult	2021
Concomitant use of levofloxacin and fluconazole leading to possible torsades de pointes. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:8 Topics: Adult; Electrocardiography; Female; Fluconazole; Humans; Levofloxacin; Long QT Syndrome; Risk Factors; Torsades de Pointes	2019
Risk screening for long QT prior to prescribing levofloxacin. The American journal of emergency medicine, 2014, Volume: 32, Issue:9 Topics: Aged; Anti-Bacterial Agents; Contraindications; Electrocardiography; Emergency Service, Hospital; Female; Humans; Levofloxacin; Long QT Syndrome; Pneumonia, Bacterial; Risk Factors; Torsades de Pointes	2014
Rare Incidence of Ventricular Tachycardia and Torsades de Pointes in Hospitalized Patients With Prolonged QT Who Later Received Levofloxacin: A Retrospective Study. Mayo Clinic proceedings, 2015, Volume: 90, Issue:5 Topics: Aged; Anti-Bacterial Agents; Female; Hospitalization; Humans; Incidence; Levofloxacin; Long QT Syndrome; Male; Middle Aged; Retrospective Studies; Tachycardia, Ventricular; Torsades de Pointes	2015
Drug Induced ECG Abnormalities. American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2015, Volume: 24, Issue:4 Topics: Anti-Bacterial Agents; Bronchitis; Electrocardiography; Female; Humans; Levofloxacin; Long QT Syndrome; Middle Aged	2015
Levofloxacin-Induced QTc Prolongation Depends on the Time of Drug Administration. CPT: pharmacometrics & systems pharmacology, 2016, Volume: 5, Issue:9 Topics: Administration, Oral; Adult; Circadian Rhythm; Clinical Trials as Topic; Computer Simulation; Cross-Over Studies; Drug Administration Schedule; Electrocardiography; Heart Conduction System; Humans; Levofloxacin; Long QT Syndrome; Male; Middle Aged; Random Allocation; Young Adult	2016
Time of the Day and Magnitude of the Effect of a Drug on the QTc Interval. CPT: pharmacometrics & systems pharmacology, 2017, Volume: 6, Issue:5 Topics: Electrocardiography; Humans; Levofloxacin; Long QT Syndrome	2017
Development of a risk score for QTc-prolongation: the RISQ-PATH study. International journal of clinical pharmacy, 2017, Volume: 39, Issue:2 Topics: Aged; Female; Fluconazole; Haloperidol; Humans; Levofloxacin; Long QT Syndrome; Male; Models, Statistical; Predictive Value of Tests; Risk Factors; ROC Curve	2017
Effect of combined fluoroquinolone and azole use on QT prolongation in hematology patients. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3 Topics: Adult; Aged; Antifungal Agents; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Fluconazole; Hematologic Neoplasms; Humans; Hypokalemia; Levofloxacin; Long QT Syndrome; Male; Middle Aged; Mycoses; Ofloxacin; Pyrimidines; Risk Factors; Torsades de Pointes; Triazoles; Ventricular Dysfunction, Left; Voriconazole	2013
Moxifloxacin: new preparation. A me-too with more cardiac risks. Prescrire international, 2002, Volume: 11, Issue:62 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Approval; Fluoroquinolones; France; Humans; Levofloxacin; Long QT Syndrome; Ofloxacin; Pneumonia	2002
QTc prolongation associated with combination therapy of levofloxacin, imipramine, and fluoxetine. The Annals of pharmacotherapy, 2005, Volume: 39, Issue:3 Topics: Anti-Infective Agents, Urinary; Antidepressive Agents; Cytochrome P-450 CYP2D6 Inhibitors; Drug Synergism; Female; Fluoxetine; Humans; Imipramine; Levofloxacin; Long QT Syndrome; Middle Aged; Ofloxacin	2005
Effect of ciprofloxacin and levofloxacin on the QT interval: is this a significant "clinical" event? Southern medical journal, 2006, Volume: 99, Issue:1 Topics: Aged; Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Electrocardiography; Female; Follow-Up Studies; Humans; Levofloxacin; Long QT Syndrome; Male; Ofloxacin; Prognosis; Prospective Studies; Prostatitis; Respiratory Tract Infections; Severity of Illness Index; Urinary Tract Infections	2006
Post-marketing surveillance of the safety of levofloxacin in Japan. Chemotherapy, 2007, Volume: 53, Issue:2 Topics: Achilles Tendon; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Chemical and Drug Induced Liver Injury; Female; Humans; Hypoglycemia; Japan; Levofloxacin; Liver Diseases; Long QT Syndrome; Male; Middle Aged; Ofloxacin; Photosensitivity Disorders; Product Surveillance, Postmarketing; Seizures; Torsades de Pointes	2007
QTC interval prolongation and polymorphic ventricular tachycardia in association with levofloxacin. The American journal of medicine, 1999, Volume: 107, Issue:5 Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Electrocardiography; Female; Heart Conduction System; Humans; Levofloxacin; Long QT Syndrome; Ofloxacin; Tachycardia, Ventricular	1999
Proarrhythmic effects of fluoroquinolone antibacterial agents: in vivo effects as physiologic substrate for torsades. Toxicology and applied pharmacology, 2000, Nov-15, Volume: 169, Issue:1 Topics: Action Potentials; Animals; Anti-Infective Agents; Dogs; Electrocardiography, Ambulatory; Female; Fluoroquinolones; Heart; Heart Block; Levofloxacin; Long QT Syndrome; Male; Models, Animal; Ofloxacin; Torsades de Pointes; Ventricular Dysfunction, Right	2000