Page last updated: 2024-09-04

levofloxacin and Acute Liver Injury, Drug-Induced

levofloxacin has been researched along with Acute Liver Injury, Drug-Induced in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (30.56)29.6817
2010's22 (61.11)24.3611
2020's3 (8.33)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cao, Y; He, K; Liang, J; Wang, T; Wang, X; Xue, J1
Chen, KH; Chen, YL; Hung, CC; Lin, SW; Liu, WD; Wang, JT; Wang, YC1
Abd Eldaim, MA; Abdallah, AEM; Abdel-Daim, MM; Abdelaziz, SAM; Abdul Rashid, S; Abdullah, AS; Abdullah, LC; Abramson, MJ; Ahmed, HB; Ahmed, MM; Ahn, YC; Alexander, DC; Ando, T; Angelone, AM; Anglani, F; Ap, Y; Arthanari, SK; Axelrad, C; Bai, S; Bakonyi, P; Barnes, E; Beckmann, NA; Bélafi-Bakó, K; Bennett, CM; Bestha, RM; Bitsch, RG; Bradley, CA; Bu, Y; Calò, LA; Cañedo-Villaroya, E; Carlson, L; Caruso, S; Casado-Flores, J; Ceol, M; Cesarino, I; Chen, IL; Chen, R; Chen, X; Chilvers, MI; Cho, WK; Choong, TSY; Conceição-Neto, N; Culver, EL; Dai, X; de Lama Caro-Patón, G; De Rosa, I; Del Prete, D; Dharmage, SC; Dimitriadis, E; Dittakavi, S; Dobrowolski, JC; Edin, S; Elgarawany, GE; Emam, HE; Emmens, RW; Erbas, B; Erwich, JJHM; Farghali, M; Feng, L; Funston, RN; Gabler, NK; Gale, P; Ganesh, M; Gao, J; Gao, L; Gao, X; García-Salido, A; Gatto, R; Gautam, S; Ge, C; Ghogomu, SM; Gianesello, L; Gonçales, VR; Gooch, JL; Gooding, JJ; Gourley, GG; Gu, H; Gu, X; Gu, Z; Guerreri, M; Guillén, M; Hazzaa, SM; Heylen, E; Hicks, R; Hong, X; Hoshi, M; Hu, B; Hu, LX; Hu, R; Hu, S; Huang, J; Huang, K; Hubbard, WB; Hui, J; Hwang, NY; Iannacci, J; Ianus, A; Iglesias-Bouzas, MI; Ihara, I; Iwasaki, M; Jaeger, S; Kandel, YR; Karpińska, G; Kim, HK; Klopfenstein, TJ; Knorr, D; Koók, L; Kotb, S; Kruithof, S; Larsson, P; Laurence, C; Leng, J; Li, H; Li, J; Li, Q; Li, S; Li, X; Li, Z; Lian, J; Liang, JX; Liang, X; Lighaam, LC; Lin, CW; Lin, HC; Lin, J; Ling, A; Liu, J; Liu, P; Liu, YS; Ljuslinder, I; Lo, GH; Lodge, CJ; Löfgren-Burström, A; Lowe, AJ; Lu, M; Lu, N; Lucero-Prisno, DE; Luebbe, KM; Luo, X; Ma, Z; Maes, P; Makuch, M; Malekbala, MR; Mao, Z; Martínez-Romera, I; Marzo, G; Mathew, FM; Mattei, A; Matthijnssens, J; Mayumi, M; Morita, N; Mueller, DS; Mullangi, R; Mummolo, S; Murthi, P; Myte, R; Nabeshima, T; Nakamoto, K; Nehdi, IA; Nemestóthy, N; Niessen, HWM; Noh, JM; Nota, A; Nunes, D; Oh, D; Öhlund, D; Olsen, KM; Ono, H; Osawa, Y; Palmqvist, R; Palombo, M; Park, M; Patience, JF; Peng, Y; Perng, DS; Persano, A; Priante, G; Prince, SJ; Pulipati, S; Pyo, H; Qiu, X; Quan, J; Quaranta, F; Quinzi, V; Rademacher, CJ; Rajaraman, G; Rashid, U; Rauch, JC; Rector, A; Remmerswaal, EBM; Ren, R; Rispens, T; Rocha, GS; Saad, NM; Saito, K; Salamova, A; Sarfaraz, K; Satoshi, A; Schnellmann, RG; Scholpa, NE; Schonhoff, M; Schwartz, KJ; Schwarze, M; Schweer, WP; Seiichi, Y; Serrano-González, A; Severino, J; Shemesh, N; Shi, ZQ; Shike, DW; Shim, YM; Siciliano, PA; Siebenrock, KA; Silva, MKL; Smith, DL; Soltani, S; Song, YM; Spry, ML; Stalker, LA; Stokes, RS; Sullivan, PG; Sun, JM; Sun, S; Svanes, C; Syo, K; Tai, CM; Takashima, S; Tashita, C; Taurino, A; Ten Berge, IJM; Tenuta, AU; Teo, SH; Tilley, RD; Trivedi, RK; Umetsu, K; Unger, PA; van Bruggen, R; van Ham, SM; Van Ranst, M; Vanitha, J; Vekaria, HJ; Venier, M; Venkateshwaran, K; Venkert, A; Vermeulen, E; Wan, C; Wang, H; Wang, N; Wang, P; Wang, T; Wang, X; Wang, Y; Wise, KA; Wolbink, GJ; Wu, J; Wu, P; Wu, S; Wu, Y; Xia, Q; Xin, W; Xiong, Q; Xu, H; Xu, P; Xue, S; Yamamoto, Y; Yamashiro, T; Yan, F; Yan, H; Yan, S; Yan, Y; Yang, JM; Yang, L; Yang, P; Ye, W; Yeh, JH; Yinda, CK; Ying, GG; Ying, L; Yoon, HG; Yu, H; Zainuddin, M; Zakkula, A; Zeller, M; Zeng, Y; Zha, J; Zhang, F; Zhang, H; Zhang, M; Zhang, Q; Zhang, S; Zhang, T; Zhang, Z; Zhao, C; Zhao, J; Zhao, Y; Zhong, Q; Zhu, J; Zingmark, C; Zo, JI; Zou, Y1
Bleumink, R; Bol-Schoenmakers, M; Giustarini, G; Kruijssen, L; Pieters, R; Smit, J; van Roest, M; Weaver, RJ1
Becak, D; Schloss, M; Tosto, ST; Velayati, A1
Ansart, S; Gazeau, P; Quaesaet, L; Rezig, S; Tande, D; Williams, T1
Farid, AS; Hegazy, AM1
Bruguera, M; Forns, X; García Juárez, I; Miquel, R1
Alshammari, TM; Caffrey, AR; LaPlante, KL; Larrat, EP; Morrill, HJ; Quilliam, BJ1
Kruhlak, NL; Zhu, X1
Levine, C; Perumalswami, PV; Thung, SN; Trivedi, A1
Bharti, H; Bhushan, B; Chander, R; Gupta, A; Kajal, NC; Ranga, V1
Crogan-Grundy, C; Funk, J; Nguyen, DG; Presnell, SC; Robbins, JB; Roth, AB; Singer, T1
Blomme, EA; Ditewig, AC; Ganey, PE; Liguori, MJ; Roth, RA; Shaw, PJ; Waring, JF1
Andrade, RJ; Carrascosa, MF; Caviedes, JR; Lavín, AC; Lucena, MI; Mones, JC; Rivero, AP; Serrano, VB1
Figueira-Coelho, J; Mendonça, P; Neta, J; Neves-Costa, J; Pereira, O; Picado, B1
Andrade, RJ; Hallal, H; Robles, M; Titos-Arcos, JC1
Coelho, J; Gonçalves, C; Leitão, S; Marques Dos Santos, R; Nascimento Costa, J1
Bielsa, S; Porcel, JM; Pubill-Fondevila, N1
Lee, CH; Schwalm, JD1
Airey, K; Koller, E1
Capony, P; Duffournet, V; Heluwaert, F; Martin, D; Roblin, X1
Alvarez-Lerma, F; Bermejo, B; León, C; Olaechea, P; Palomar, M; Sánchez, M1
Kawai, H; Komiya, M; Matsumoto, T; Nakayasu, T; Shimada, J; Yamaguchi, H; Yokoyama, H1
Ganey, PE; Hopfensperger, MJ; Roth, RA; Shaw, PJ1
Yagawa, K1
Armenian, B; Hadengue, A; Marinescu, O; Rubbia-Brandt, L; Spahr, L1
Ahmed, S; Karim, A; Rossoff, LJ; Siddiqui, RK; Steinberg, HN1

Reviews

5 review(s) available for levofloxacin and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
High-dose rifampicin for the treatment of tuberculous meningitis: a meta-analysis of randomized controlled trials.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Humans; Levofloxacin; Randomized Controlled Trials as Topic; Rifampin; Tuberculosis, Meningeal

2022
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays

2013
Severe ductopenia and cholestasis from levofloxacin drug-induced liver injury: a case report and review.
    Seminars in liver disease, 2014, Volume: 34, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Bile Ducts; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Levofloxacin; Liver Cirrhosis

2014
Latest industry information on the safety profile of levofloxacin in Japan.
    Chemotherapy, 2001, Volume: 47 Suppl 3

    Topics: Adverse Drug Reaction Reporting Systems; Anti-Infective Agents; Central Nervous System; Chemical and Drug Induced Liver Injury; Dermatitis, Phototoxic; Drug Industry; Fluoroquinolones; Heart Diseases; Humans; Japan; Levofloxacin; Naphthyridines; Ofloxacin; Seizures; Substance Withdrawal Syndrome

2001

Trials

1 trial(s) available for levofloxacin and Acute Liver Injury, Drug-Induced

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays

2013

Other Studies

31 other study(ies) available for levofloxacin and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Pyrazinamide related prolonged drug-induced liver injury: A case report.
    Medicine, 2022, Sep-30, Volume: 101, Issue:39

    Topics: Antitubercular Agents; Arylamine N-Acetyltransferase; Chemical and Drug Induced Liver Injury; Ethambutol; Humans; Levofloxacin; Pyrazinamide; Transaminases; Tuberculosis, Lymph Node

2022
Tissue influx of neutrophils and monocytes is delayed during development of trovafloxacin-induced tumor necrosis factor-dependent liver injury in mice.
    Journal of applied toxicology : JAT, 2018, Volume: 38, Issue:5

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cytokines; Flow Cytometry; Fluoroquinolones; Leukocytes; Levofloxacin; Liver; Male; Mice; Mice, Inbred C57BL; Monocytes; Naphthyridines; Neutrophils; Tumor Necrosis Factor-alpha

2018
A Case of Levofloxacin-Induced Hepatotoxicity.
    The American journal of case reports, 2018, Mar-10, Volume: 19

    Topics: Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Humans; Levofloxacin; Liver; Male; Young Adult

2018
Erysipelothrix rhusiopathiae knee prosthesis infection.
    Medecine et maladies infectieuses, 2018, Volume: 48, Issue:5

    Topics: Aged, 80 and over; Amoxicillin; Arthroplasty, Replacement, Knee; Ceftriaxone; Chemical and Drug Induced Liver Injury; Drug Substitution; Erysipelothrix; Erysipelothrix Infections; Humans; Knee Prosthesis; Levofloxacin; Male; Prosthesis-Related Infections; Recurrence; Reoperation; Sepsis

2018
Ameliorative effects of
    Drug and chemical toxicology, 2020, Volume: 43, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Inflammation Mediators; Interleukin-1; Interleukin-10; Levofloxacin; Liver; Male; Moringa oleifera; Oxidative Stress; Plant Extracts; Plant Leaves; Rats, Wistar

2020
[Levofloxacin-induced autoimmune hepatitis. Description of a case].
    Gastroenterologia y hepatologia, 2014, Volume: 37, Issue:1

    Topics: Adrenal Cortex Hormones; Alanine Transaminase; Anti-Asthmatic Agents; Aspartate Aminotransferases; Asthma; Biopsy; Chemical and Drug Induced Liver Injury; Eosinophilia; Female; Hepatitis, Autoimmune; Humans; Levofloxacin; Liver; Middle Aged; Nasal Polyps; Prednisone; Recurrence; Respiratory Tract Infections

2014
Risk of hepatotoxicity associated with fluoroquinolones: a national case-control safety study.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2014, Jan-01, Volume: 71, Issue:1

    Topics: Adult; Aged; Alcoholism; Anti-Bacterial Agents; Aza Compounds; Case-Control Studies; Chemical and Drug Induced Liver Injury; Ciprofloxacin; Comorbidity; Data Interpretation, Statistical; Databases, Factual; Female; Fluoroquinolones; Hospitals, Veterans; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Patient Safety; Quinolines; Retrospective Studies; Risk Factors; Socioeconomic Factors; United States; United States Department of Veterans Affairs

2014
Construction and analysis of a human hepatotoxicity database suitable for QSAR modeling using post-market safety data.
    Toxicology, 2014, Jul-03, Volume: 321

    Topics: Algorithms; Ampicillin; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Bile Duct Diseases; Calibration; Chemical and Drug Induced Liver Injury; Cholestasis; Data Mining; Databases, Factual; Drug Labeling; Endpoint Determination; Humans; Levofloxacin; Liver; Naproxen; Product Surveillance, Postmarketing; Quantitative Structure-Activity Relationship; Toxicity Tests; Vitamins

2014
Profile of adverse drug reactions in drug resistant tuberculosis from Punjab.
    The Indian journal of tuberculosis, 2014, Volume: 61, Issue:4

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Arthralgia; Ataxia; Chemical and Drug Induced Liver Injury; Child; Cycloserine; Drug Eruptions; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; Gastrointestinal Diseases; Hearing Loss; Humans; Hypothyroidism; India; Kanamycin; Levofloxacin; Male; Middle Aged; Peripheral Nervous System Diseases; Psychoses, Substance-Induced; Pyrazinamide; Severity of Illness Index; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Vision Disorders; Young Adult

2014
Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Albumins; Bioprinting; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Drug-Related Side Effects and Adverse Reactions; Fluoroquinolones; Hepatocytes; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Levofloxacin; Lipopolysaccharides; Liver; Naphthyridines; Platelet Endothelial Cell Adhesion Molecule-1

2016
Coexposure of mice to trovafloxacin and lipopolysaccharide, a model of idiosyncratic hepatotoxicity, results in a unique gene expression profile and interferon gamma-dependent liver injury.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 107, Issue:1

    Topics: Analysis of Variance; Animals; Chemical and Drug Induced Liver Injury; Female; Fluoroquinolones; Gene Expression; Hepatocytes; Inflammation; Interferon-gamma; Interleukin-18; Janus Kinases; Levofloxacin; Lipopolysaccharides; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Naphthyridines; Necrosis; Ofloxacin; Oligonucleotide Array Sequence Analysis; STAT Transcription Factors; Transcriptional Activation

2009
Fatal acute hepatitis after sequential treatment with levofloxacin, doxycycline, and naproxen in a patient presenting with acute Mycoplasma pneumoniae infection.
    Clinical therapeutics, 2009, Volume: 31, Issue:5

    Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Doxycycline; Fatal Outcome; Hepatitis; Humans; Levofloxacin; Liver Failure, Acute; Male; Middle Aged; Naproxen; Ofloxacin; Pericarditis; Pneumonia, Mycoplasma

2009
Acute hepatitis associated with the use of levofloxacin.
    Clinical therapeutics, 2010, Volume: 32, Issue:10

    Topics: Acute Disease; Aged; Anti-Bacterial Agents; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Humans; Levofloxacin; Liver Function Tests; Male; Ofloxacin; Pneumonia; Treatment Outcome

2010
[Acute cholestatic hepatitis associated with levofloxacin].
    Gastroenterologia y hepatologia, 2011, Volume: 34, Issue:5

    Topics: Acute Disease; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin

2011
[Levofloxacin hepatotoxicity. Higher risk in diabetics?].
    Acta medica portuguesa, 2011, Volume: 24 Suppl 3

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Type 2; Female; Humans; Levofloxacin; Liver; Male; Ofloxacin

2011
[Levofloxacin hepatotoxicity].
    Medicina clinica, 2013, Mar-16, Volume: 140, Issue:6

    Topics: Adult; Alanine Transaminase; Anti-Bacterial Agents; Aspartate Aminotransferases; Bronchiectasis; Bronchitis; Ceftriaxone; Chemical and Drug Induced Liver Injury; Drug Substitution; gamma-Glutamyltransferase; Hepatomegaly; Humans; Hyperbilirubinemia; Levofloxacin; Male; Ofloxacin

2013
Acute hepatitis associated with oral levofloxacin therapy in a hemodialysis patient.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003, Apr-01, Volume: 168, Issue:7

    Topics: Acute Disease; Aged; Anti-Infective Agents; Cellulitis; Chemical and Drug Induced Liver Injury; Humans; Kidney Failure, Chronic; Levofloxacin; Male; Ofloxacin; Renal Dialysis

2003
Acute hepatitis associated with levofloxacin in a patient with renal insufficiency.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003, Oct-14, Volume: 169, Issue:8

    Topics: Acute Disease; Alkaline Phosphatase; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Epistaxis; Female; Humans; Kidney Failure, Chronic; Levofloxacin; Middle Aged; Ofloxacin

2003
[Hepatitis related to amoxicillin or levofloxacin: a case report].
    La Revue de medecine interne, 2003, Volume: 24, Issue:12

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Levofloxacin; Ofloxacin

2003
[Observational study investigating the use of levofloxacin in ICU patients].
    Enfermedades infecciosas y microbiologia clinica, 2004, Volume: 22, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Arrhythmias, Cardiac; Bacterial Infections; Chemical and Drug Induced Liver Injury; Community-Acquired Infections; Comorbidity; Critical Care; Cross Infection; Diarrhea; Drug Resistance; Drug Therapy, Combination; Drug Utilization; Female; Humans; Infusions, Parenteral; Intensive Care Units; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Respiration, Artificial; Respiratory Tract Infections; Spain

2004
Post-marketing surveillance of the safety of levofloxacin in Japan.
    Chemotherapy, 2007, Volume: 53, Issue:2

    Topics: Achilles Tendon; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Chemical and Drug Induced Liver Injury; Female; Humans; Hypoglycemia; Japan; Levofloxacin; Liver Diseases; Long QT Syndrome; Male; Middle Aged; Ofloxacin; Photosensitivity Disorders; Product Surveillance, Postmarketing; Seizures; Torsades de Pointes

2007
Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 100, Issue:1

    Topics: Alanine Transaminase; Animals; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Etanercept; Fluoroquinolones; Immunoglobulin G; Inflammation; Levofloxacin; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Naphthyridines; Ofloxacin; Pentoxifylline; Receptors, Tumor Necrosis Factor; Time Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha

2007
Acute fatal hepatitis related to levofloxacin.
    Journal of hepatology, 2001, Volume: 35, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Chemical and Drug Induced Liver Injury; Fatal Outcome; Humans; Levofloxacin; Liver Failure, Acute; Male; Ofloxacin; Urinary Tract Infections

2001
Possible levofloxacin-induced acute hepatocellular injury in a patient with chronic obstructive lung disease.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Dec-15, Volume: 33, Issue:12

    Topics: Acute Disease; Aged; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Infusions, Intravenous; Levofloxacin; Liver; Liver Diseases; Liver Function Tests; Ofloxacin; Pulmonary Disease, Chronic Obstructive

2001