Page last updated: 2024-08-17

levodopa and Drug Withdrawal Symptoms

levodopa has been researched along with Drug Withdrawal Symptoms in 100 studies

Research

Studies (100)

Timeframe	Studies, this research(%)	All Research%
pre-1990	33 (33.00)	18.7374
1990's	32 (32.00)	18.2507
2000's	26 (26.00)	29.6817
2010's	8 (8.00)	24.3611
2020's	1 (1.00)	2.80

Authors

Authors	Studies
Jost, WH; Koschel, J; Raeder, V; Ray Chaudhuri, K; Thiel, M; Tönges, L	1
Casier, I; Hantson, P; Jeanjean, A	1
Cannas, A; Fasano, A; Lang, AE; Marrosu, F; Marrosu, MG; Mulas, CS; Solla, P	1
Ablordeppey, E; Taylor, B; Whitman, CB	1
Antonini, A; Cossu, G; Mancini, F; Modugno, N; Pilleri, M; Quatrale, R; Sensi, M; Tamma, F; Zibetti, M	1
Frisina, PG; Gracies, JM; Hälbig, TD; Koller, WC; Lesser, G; Liang, L; Libow, LS; Neufeld, R; Tarshish, C; Tse, W	1
Ba, M; Kong, M; Liu, Z; Song, L	1
San Luciano, M; Saunders-Pullman, R	1
Cresswell, SA; Evans, AH; Katzenschlager, R; Lawrence, AD; Lees, AJ	1
Man, SP	1
Domino, EF; Jutkiewicz, EM; Ohmura, Y	1
McKeown, MJ; Oishi, MM; Stevenson, JK; Talebifard, P; Ty, E	1
Borra, S; Hauser, RA; Zesiewicz, TA	1
Kleiner-Fisman, G; Lang, AE; Lozano, A; Miyasaki, J; Saint-Cyr, JA	1
Agid, Y; Bejjani, BP; Houeto, JL; Mallet, L; Mesnage, V; Welter, ML	1
Serrano-Dueñas, M	1
Kuno, S; Mizuno, Y; Mizuta, E; Takubo, H	1
Hanyu, N; Hashimoto, T; Tabata, K; Tokuda, T; Yanagisawa, N	1
Mizuno, Y; Shimoda-Matsubayashi, S; Takubo, H	1
Ahmed, SM; Chartisathian, K; Chase, TN; Oh, JD	1
Castro, A; Dapena, MD; Linazasoro, G; Van Blercom, N	1
Al-Din, A; Lily, O	1
Ladha, SS; Shill, HA; Walker, R	1
Ward, C	1
Iyer, SS; Morgan, JC; Sethi, KD	1
Brodsky, MA; Hogarth, P; Nutt, JG	1
Brooks, DJ; Goerendt, IK; Lawrence, AD	1
Douglas, A; Morris, J	1
Mutani, R; Sechi, GP; Tanda, F	1
Bear, G; Casson, I; Durso, R; Foo, SH; Goldstein, M; Khayali, M; Kupersmith, M; Lieberman, A; Neophytides, A	1
Bailey, R; Crisp, E; Jackson, DM; Jenkins, O	1
Armando, I; Clow, A; Glover, V; Sandler, M	1
Goetz, CG; Klawans, HL; Koller, WC; Nausieda, PA; Perlik, S; Weiner, WJ	1
Ghosh, MN; Gopalakrishnan, V; Pillai, NP; Ramaswamy, S	1
Chatel, DM; Dahdal, WY; Franson, KL; Grossberg, GT; Hay, DP; Kotegal, S; Mirza, WU; Neppe, V; Szwabo, PA	1
Collier, TJ; Junn, FS; Sladek, JR; Steece-Collier, K; Yurek, DM	1
Carey, RJ; Huston, JP; Pinheiro-Carrera, M; Tomaz, C	1
Gershteĭn, LM; Kukuev, LA; Sergutina, AV	1
Cetel, M; Guilleminault, C; Philip, P	1
Cape, G	1
González, J; Masana, L; Olivé, JM	1
Fernandez, W; Lees, AJ; Turjanski, N	1
Cheng, FC; Chia, LG; Kuo, JS	1
Angrist, B; Sanfilipo, M; Wolfsohn, R	1
Bravi, D; Chase, TN; Davis, TL; Mouradian, MM; Roberts, JW	1
Kornhuber, J; Weller, M	1
Lange, KW; Marsden, CD; Paul, GM; Robbins, TW	1
Kaufman, BS; Young, CC	1
Fuchs, G	1
Barbato, L; Marsden, CD; Monge, A; Nordera, G; Ruggieri, S; Stocchi, F; Vacca, L	1
el-Kadi, AO; Sharif, SI	1
Kobayashi, T; Muneta, S; Saeki, H	1
Horikawa, Y; Iijima, K; Koganei, H; Tanaka, O; Tanaka, S	1
Busenbark, K; Hauser, RA; Hubble, JP; Koller, WC; Malapira, T; Olanow, CW	1
Bonoma, RA; Iwuagwu, CU; Riley, D	1
Galili-Mosberg, R; Melamed, E; Merims, D	1
Chew, EL; Ong, KC; Ong, YY	1
Bonanni, L; Di Iorio, A; Iacono, D; Onofrj, M; Thomas, A	1
Onofrj, M; Paci, C; Thomas, A	1
Frucht, SJ; Gordon, PH	1
Bunney, WE; Kopanda, RT; Murphy, DL	1
Kruszewska, A; Langwiński, R	1
Timberlake, WH; Vance, MA	1
Laplane, D	1
Bhargava, HN	1
Blum, K; Eubanks, JD; Schwertner, HA; Wallace, JE	1
Bantoutova, I; Kobourova, K; Ovcharov, R	1
Blum, K; Eubanks, JD; Morgan, WW; Schwertner, H; Wallace, JE	1
Colpaert, FC; Laduron, P; Lal, H	1
Kuschinsky, K	1
Heninger, GR; Kleber, HD; Kosten, TR; McDougle, CJ; Palumbo, JM; Price, LH	1
Brown, RG; Jahanshahi, M; Marsden, CD	1
Bonuccelli, U; Corsini, GU; Muratorio, A; Piccini, P	1
James, M; Lange, KW; Marsden, CD; Owen, AM; Paul, GM; Robbins, TW	1
Campbell, N; Evans, C; Franco, K; Pentz, J; Tamburrino, M	1
Carey, RJ	1
Eriksson, T; Oberg, B; Pedersen, SW	1
Lefeber, EJ; Rainer, C; Scheinost, NA	1
Goldswain, PR; Harrison, WB; Reutens, DC	1
Montastruc, JL; Rascol, O; Salachas, F	1
Meltzer, HY; Parsa, MA; Ramirez, LF; Rohr, T	1
Angrist, B; Wolfsohn, R	1
Choi, P; Parrott, A	1
Boyce, S; Jenner, P; Marsden, CD	1
De Cuypere, G; Jannes, C; Remouchamps, A; Tack, E	1
Agid, Y; Bonnet, AM; Javoy-Agid, F; Ruberg, M	1
Kantak, KM; Miczek, KA	1
Gibb, WR	1
Lees, AJ; Poewe, WH; Stern, GM	1
Berman, ML; Tennant, F	1
Greenberg, HS; Hirschorn, KA	1
Lang, AE	1
Golubev, VL; Orlova, OR	1
Iacono, RP; Sandyk, R	1
Gibb, WR; Griffith, DN	1
Maesner, JE	1
Clow, A; Murray, R; Sandler, M; Saunders, JB; Topham, A	1
Feinberg, SS; Feldman, RG; Friedman, JH	1

Reviews

8 review(s) available for levodopa and Drug Withdrawal Symptoms

Article	Year
Implications of dopaminergic medication withdrawal in Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996), 2022, Volume: 129, Issue:9 Topics: Amantadine; Dopamine; Dopamine Agonists; Humans; Levodopa; Parkinson Disease; Substance Withdrawal Syndrome	2022
Substance abuse and movement disorders. Current drug abuse reviews, 2009, Volume: 2, Issue:3 Topics: Alcoholism; Animals; Apomorphine; Humans; Levodopa; Movement Disorders; Parkinson Disease; Substance Withdrawal Syndrome; Substance-Related Disorders	2009
Malignant syndrome in Parkinson's disease: concept and review of the literature. Parkinsonism & related disorders, 2003, Volume: 9 Suppl 1 Topics: Antiparkinson Agents; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	2003
Drug-induced seizures in the elderly. Causative agents and optimal management. Drugs & aging, 1995, Volume: 7, Issue:1 Topics: Aging; Anti-Bacterial Agents; Anti-Infective Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Central Nervous System Agents; Histamine H2 Antagonists; Humans; Lactams; Levodopa; Seizures; Substance Withdrawal Syndrome; Theophylline	1995
L-dopa and frontal cognitive function in Parkinson's disease. Advances in neurology, 1993, Volume: 60 Topics: Aged; Dementia; Frontal Lobe; Humans; Levodopa; Mental Processes; Neuropsychological Tests; Parkinson Disease; Prefrontal Cortex; Substance Withdrawal Syndrome	1993
Neuroleptic malignant syndrome. When levodopa withdrawal is the cause. Postgraduate medicine, 1991, Volume: 89, Issue:5 Topics: Aged; Carbidopa; Humans; Levodopa; Male; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	1991
[Neuroleptic malignant-like syndrome following levodopa withdrawal]. Revue neurologique, 1990, Volume: 146, Issue:3 Topics: Aged; Humans; Levodopa; Male; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	1990
Receptor changes during chronic dopaminergic stimulation. Journal of neural transmission. Supplementum, 1988, Volume: 27 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Brain Diseases; Bromocriptine; Dopamine; Humans; Hydroxydopamines; Injections, Intraperitoneal; Levodopa; Neurotransmitter Agents; Oxidopamine; Parkinson Disease; Pergolide; Primates; Pyridines; Receptors, Dopamine; Substance Withdrawal Syndrome	1988

Trials

8 trial(s) available for levodopa and Drug Withdrawal Symptoms

Article	Year
The effects of withdrawal of dopaminergic medication in nursing home patients with advanced parkinsonism. Journal of the American Medical Directors Association, 2008, Volume: 9, Issue:9 Topics: Aged; Aged, 80 and over; Dopamine Agents; Double-Blind Method; Female; Humans; Levodopa; Male; New York City; Nursing Homes; Parkinson Disease; Severity of Illness Index; Substance Withdrawal Syndrome	2008
Dyskinetic Parkinson's disease patients demonstrate motor abnormalities off medication. Experimental brain research, 2011, Volume: 214, Issue:3 Topics: Aged; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Psychomotor Performance; Substance Withdrawal Syndrome	2011
A placebo-controlled trial of L-dopa/carbidopa in early cocaine abstinence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 9, Issue:1 Topics: Adult; Breath Tests; Carbidopa; Cocaine; Drug Combinations; Electrocardiography; Humans; Levodopa; Substance Withdrawal Syndrome	1993
Entacapone improves motor fluctuations in levodopa-treated Parkinson's disease patients. Parkinson Study Group. Annals of neurology, 1997, Volume: 42, Issue:5 Topics: Aged; Antiparkinson Agents; Catechols; Double-Blind Method; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Female; Humans; Levodopa; Male; Middle Aged; Movement; Nitriles; Parkinson Disease; Patient Compliance; Substance Withdrawal Syndrome; Treatment Outcome	1997
Time course of loss of clinical benefit following withdrawal of levodopa/carbidopa and bromocriptine in early Parkinson' s disease. Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:3 Topics: Aged; Antiparkinson Agents; Bromocriptine; Carbidopa; Disability Evaluation; Disease Progression; Double-Blind Method; Female; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Prospective Studies; Selegiline; Substance Withdrawal Syndrome	2000
Amantadine for dyskinesia in patients affected by severe Parkinson's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2001, Volume: 22, Issue:1 Topics: Aged; Amantadine; Antiviral Agents; Disease Progression; Dopamine Agents; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Recovery of Function; Substance Withdrawal Syndrome; Treatment Outcome	2001
Four-year treatment of patients with parkinsonism using amantadine alone or with levodopa. Annals of neurology, 1978, Volume: 3, Issue:2 Topics: Adult; Aged; Amantadine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Placebos; Substance Withdrawal Syndrome	1978
L-dopa withdrawal in Parkinson's disease selectively impairs cognitive performance in tests sensitive to frontal lobe dysfunction. Psychopharmacology, 1992, Volume: 107, Issue:2-3 Topics: Brain Diseases; Cognition Disorders; Discrimination, Psychological; Female; Frontal Lobe; Humans; Learning; Levodopa; Male; Memory; Middle Aged; Parkinson Disease; Psychomotor Performance; Substance Withdrawal Syndrome	1992

Other Studies

84 other study(ies) available for levodopa and Drug Withdrawal Symptoms

Article	Year
Postoperative hyperthermic syndrome following antiparkinsonian drugs withdrawal: the pitfall of enteral refeeding. Anaesthesia and intensive care, 2013, Volume: 41, Issue:6 Topics: Aged, 80 and over; Antiparkinson Agents; Diagnosis, Differential; Drug Administration Schedule; Drug Interactions; Enteral Nutrition; Follow-Up Studies; Humans; Intubation, Gastrointestinal; Levodopa; Male; Malignant Hyperthermia; Neuroleptic Malignant Syndrome; Postoperative Period; Substance Withdrawal Syndrome	2013
Dopamine agonist withdrawal syndrome (DAWS) symptoms in Parkinson's disease patients treated with levodopa-carbidopa intestinal gel infusion. Parkinsonism & related disorders, 2015, Volume: 21, Issue:8 Topics: Aged; Anhedonia; Apathy; Carbidopa; Dopamine Agonists; Drug Combinations; Female; Gels; Humans; Infusions, Parenteral; Levodopa; Male; Middle Aged; Parkinson Disease; Substance Withdrawal Syndrome	2015
Levodopa Withdrawal Presenting as Fever in a Critically Ill Patient Receiving Concomitant Enteral Nutrition. Journal of pharmacy practice, 2016, Volume: 29, Issue:6 Topics: Aged; Combined Modality Therapy; Enteral Nutrition; Fever; Food-Drug Interactions; Humans; Levodopa; Male; Substance Withdrawal Syndrome	2016
Which patients discontinue? Issues on Levodopa/carbidopa intestinal gel treatment: Italian multicentre survey of 905 patients with long-term follow-up. Parkinsonism & related disorders, 2017, Volume: 38 Topics: Antiparkinson Agents; Carbidopa; Disease Progression; Drug Combinations; Female; Gels; Health Surveys; Humans; Intestines; Italy; Levodopa; Longitudinal Studies; Male; Parkinson Disease; Retrospective Studies; Substance Withdrawal Syndrome	2017
Comparative effects of acute or chronic administration of levodopa to 6-OHDA-lesioned rats on the expression and phosphorylation of N-methyl-D-aspartate receptor NR1 subunits in the striatum. Neurochemical research, 2009, Volume: 34, Issue:8 Topics: Animals; Blotting, Western; Dopamine Agents; Female; Indicators and Reagents; Levodopa; Movement; Neostriatum; Nerve Tissue Proteins; Oxidopamine; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Sympatholytics	2009
Compulsive use of dopaminergic drug therapy in Parkinson's disease: reward and anti-reward. Movement disorders : official journal of the Movement Disorder Society, 2010, May-15, Volume: 25, Issue:7 Topics: Affect; Compulsive Behavior; Dopamine Agonists; Drug Administration Schedule; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Severity of Illness Index; Substance Withdrawal Syndrome; Surveys and Questionnaires; Treatment Outcome	2010
An uncommon adverse effect of levodopa withdrawal in a patient taking antipsychotic medication: neuroleptic malignant-like syndrome. Hong Kong medical journal = Xianggang yi xue za zhi, 2011, Volume: 17, Issue:1 Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Dopamine Agonists; Humans; Levodopa; Male; Neuroleptic Malignant Syndrome; Substance Withdrawal Syndrome	2011
L-DOPA attenuates nicotine withdrawal-induced behaviors in rats. Pharmacology, biochemistry, and behavior, 2011, Volume: 98, Issue:4 Topics: Animals; Behavior, Animal; Depression; Dopamine Agents; Levodopa; Male; Motor Activity; Nicotine; Rats; Rats, Sprague-Dawley; Smoking Cessation; Substance Withdrawal Syndrome	2011
Clozapine withdrawal symptoms in a Parkinson's disease patient. Movement disorders : official journal of the Movement Disorder Society, 2002, Volume: 17, Issue:6 Topics: Aged; Antipsychotic Agents; Carbidopa; Clozapine; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Hallucinations; Humans; Levodopa; Male; Neurologic Examination; Parkinson Disease; Parkinson Disease, Secondary; Substance Withdrawal Syndrome	2002
Subthalamic DBS replaces levodopa in Parkinson's disease: two-year follow-up. Neurology, 2003, Jan-14, Volume: 60, Issue:1 Topics: Confusion; Depression; Dopamine Agonists; Dysarthria; Electric Stimulation Therapy; Follow-Up Studies; Humans; Levodopa; Motor Activity; Parkinson Disease; Substance Withdrawal Syndrome; Subthalamic Nucleus; Time; Treatment Outcome	2003
Subthalamic DBS replaces levodopa in Parkinson's disease: two-year follow-up. Neurology, 2003, Jan-14, Volume: 60, Issue:1 Topics: Confusion; Depression; Dopamine Agonists; Electric Stimulation Therapy; Follow-Up Studies; Levodopa; Mood Disorders; Neuroleptic Malignant Syndrome; Parkinson Disease; Quality of Life; Social Behavior Disorders; Substance Withdrawal Syndrome; Subthalamic Nucleus; Time; Treatment Outcome	2003
Neuroleptic malignant syndrome-like, or--dopaminergic malignant syndrome--due to levodopa therapy withdrawal. Clinical features in 11 patients. Parkinsonism & related disorders, 2003, Volume: 9, Issue:3 Topics: Adult; Aged; Analysis of Variance; Diagnosis, Differential; Female; Humans; Levodopa; Male; Middle Aged; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	2003
Withdrawal of levodopa and other risk factors for malignant syndrome in Parkinson's disease. Parkinsonism & related disorders, 2003, Volume: 9 Suppl 1 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Dehydration; Female; Fever; Health Status; Humans; Incidence; Levodopa; Male; Middle Aged; Neuroleptic Malignant Syndrome; Parkinson Disease; Risk Factors; Substance Withdrawal Syndrome	2003
Serum creatine kinase is elevated in patients with Parkinson's disease: a case controlled study. Parkinsonism & related disorders, 2003, Volume: 9 Suppl 1 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Case-Control Studies; Creatine Kinase; Female; Humans; Levodopa; Male; Middle Aged; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	2003
Cyclic AMP responsive element binding protein phosphorylation and persistent expression of levodopa-induced response alterations in unilateral nigrostriatal 6-OHDA lesioned rats. Journal of neuroscience research, 2003, Jun-15, Volume: 72, Issue:6 Topics: Animals; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; Levodopa; Male; Oxidopamine; Phosphorylation; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substantia Nigra	2003
Subthalamic deep brain stimulation masking possible malignant syndrome in Parkinson disease. Neurology, 2004, Aug-10, Volume: 63, Issue:3 Topics: Analgesics, Non-Narcotic; Anti-Infective Agents; Antiparkinson Agents; Combined Modality Therapy; Consciousness Disorders; Dantrolene; Deep Brain Stimulation; Diagnosis, Differential; Diagnostic Errors; Dystonic Disorders; Encephalitis; Female; Fluid Therapy; Foot; Humans; Levodopa; Malignant Hyperthermia; Middle Aged; Muscle Relaxants, Central; Parkinson Disease; Selegiline; Substance Withdrawal Syndrome; Tachycardia	2004
Case study: cerebrovascular parkinsonism with levodopa addiction. Journal of neurology, neurosurgery, and psychiatry, 2004, Volume: 75, Issue:9 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Cerebrovascular Disorders; Female; Humans; Levodopa; Parkinson Disease; Parkinsonian Disorders; Substance Withdrawal Syndrome; Substance-Related Disorders	2004
Case of neuroleptic malignant-like syndrome precipitated by abrupt fava bean discontinuance. Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:5 Topics: Diagnosis, Differential; Humans; Levodopa; Male; Middle Aged; Neuroleptic Malignant Syndrome; Phytotherapy; Substance Withdrawal Syndrome; Vicia faba	2005
Neuroleptic malignant syndrome in a patient with Parkinson's disease: a case study. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 2005, Volume: 37, Issue:3 Topics: Aged; Antiparkinson Agents; Confusion; Dantrolene; Deep Brain Stimulation; Dehydration; Dopamine Agents; Drug Monitoring; Electrolytes; Fever; Humans; Leukocyte Count; Levodopa; Magnetic Resonance Imaging; Male; Muscle Relaxants, Central; Neuroleptic Malignant Syndrome; Nurse's Role; Nursing Assessment; Parkinson Disease; Physical Examination; Substance Withdrawal Syndrome; Time Factors; Urinalysis	2005
Absorption of orally disintegrating carbidopa-levodopa requires intact small bowel function. Neurology, 2005, Nov-08, Volume: 65, Issue:9 Topics: Administration, Oral; Aged; Carbidopa; Disease Progression; Dopamine Agents; Drug Combinations; Female; Humans; Intestinal Pseudo-Obstruction; Intestine, Small; Levodopa; Middle Aged; Parkinson Disease; Patient Selection; Substance Withdrawal Syndrome; Treatment Failure	2005
OFF-off rebound dyskinesia in subthalamic nucleus deep brain stimulation of Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:9 Topics: Antiparkinson Agents; Carbidopa; Combined Modality Therapy; Corpus Striatum; Deep Brain Stimulation; Dominance, Cerebral; Drug Therapy, Combination; Dyskinesias; Electrodes, Implanted; Humans; Levodopa; Magnetic Resonance Imaging; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Secondary Prevention; Stereotaxic Techniques; Substance Withdrawal Syndrome; Subthalamic Nucleus	2006
Impaired recognition of facial expressions of anger in Parkinson's disease patients acutely withdrawn from dopamine replacement therapy. Neuropsychologia, 2007, Jan-07, Volume: 45, Issue:1 Topics: Aged; Anger; Antiparkinson Agents; Dopamine Agents; Emotions; Exploratory Behavior; Facial Expression; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Personality Tests; Social Perception; Substance Withdrawal Syndrome	2007
It was not just a heatwave! Neuroleptic malignant-like syndrome in a patient with Parkinson's disease. Age and ageing, 2006, Volume: 35, Issue:6 Topics: Aged; Antiparkinson Agents; Female; Fever; Humans; Levodopa; Parkinson Disease; Substance Withdrawal Syndrome	2006
Fatal hyperpyrexia after withdrawal of levodopa. Neurology, 1984, Volume: 34, Issue:2 Topics: Basal Ganglia Diseases; Dyskinesia, Drug-Induced; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Substance Withdrawal Syndrome	1984
Long-term efficacy of bromocriptine in Parkinson disease. Neurology, 1980, Volume: 30, Issue:5 Topics: Bromocriptine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Levodopa; Long-Term Care; Middle Aged; Parkinson Disease; Substance Withdrawal Syndrome	1980
Chronic L-DOPA treatment of mice: a behavioural and biochemical study. Journal of neural transmission, 1981, Volume: 50, Issue:2-4 Topics: Animals; Apomorphine; Benserazide; Body Temperature Regulation; Brain; Clonidine; Dihydroxyphenylalanine; Dopamine; Humans; Levodopa; Male; Mice; Motor Activity; Norepinephrine; Substance Withdrawal Syndrome	1981
Pictet-Spengler condensation products, stress and alcoholism: some clinical overtones. Progress in clinical and biological research, 1982, Volume: 90 Topics: Alcoholism; Animals; Carbolines; Chemical Phenomena; Chemistry; Gas Chromatography-Mass Spectrometry; Humans; Isoquinolines; Levodopa; Monoamine Oxidase Inhibitors; Papaverine; Rats; Salsoline Alkaloids; Stress, Physiological; Substance Withdrawal Syndrome; Tetrahydroisoquinolines; Tetrahydropapaveroline	1982
Complications of chronic levodopa therapy: long-term efficacy of drug holiday. Neurology, 1981, Volume: 31, Issue:4 Topics: Aged; Dyskinesia, Drug-Induced; Female; Hallucinations; Humans; Levodopa; Male; Middle Aged; Motor Activity; Parkinson Disease; Substance Withdrawal Syndrome	1981
L-Dopa induced jumping behaviour in acutely morphinized mice. Indian journal of experimental biology, 1981, Volume: 19, Issue:9 Topics: Animals; Humans; Levodopa; Male; Mice; Morphine; Motor Activity; Substance Withdrawal Syndrome	1981
The detrimental effect of levodopa on behavioral efficacy of fetal dopamine neuron grafts in rats is reversible following prolonged withdrawal of chronic dosing. Brain research, 1995, Apr-10, Volume: 676, Issue:2 Topics: Animals; Dopamine; Drug Administration Schedule; Fetal Tissue Transplantation; Levodopa; Male; Motor Activity; Neurons; Rats; Rats, Inbred F344; Rotation; Substance Withdrawal Syndrome; Time Factors	1995
NMDA antagonist effects on the development of L-dopa behavioral sensitization in rats. Behavioral neuroscience, 1995, Volume: 109, Issue:1 Topics: Animals; Dizocilpine Maleate; Dominance, Cerebral; Dopamine; Dose-Response Relationship, Drug; Levodopa; Male; Motor Activity; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substance Withdrawal Syndrome; Synaptic Transmission; Tegmentum Mesencephali	1995
[Pathochemical changes in the motor structures of the brain under the influence of the administration of L-DOPA preparations and their withdrawal (experimental research)]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1994, Volume: 94, Issue:5 Topics: Animals; Benserazide; Brain; Brain Chemistry; Drug Combinations; Histocytochemistry; Levodopa; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Time Factors	1994
Dopaminergic treatment of restless legs and rebound phenomenon. Neurology, 1993, Volume: 43, Issue:2 Topics: Aged; Carbidopa; Dopamine Agents; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Prospective Studies; Restless Legs Syndrome; Substance Withdrawal Syndrome	1993
Neuroleptic malignant syndrome--a cautionary tale and a surprising outcome. The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:1 Topics: Activities of Daily Living; Adaptation, Psychological; Adult; Antisocial Personality Disorder; Combined Modality Therapy; Critical Care; Dantrolene; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluphenazine; Follow-Up Studies; Humans; Levodopa; Male; Neuroleptic Malignant Syndrome; Neurologic Examination; Schizoid Personality Disorder; Sick Role; Social Environment; Substance Withdrawal Syndrome	1994
Meperidine and reversible parkinsonism. Movement disorders : official journal of the Movement Disorder Society, 1994, Volume: 9, Issue:1 Topics: Adult; Benserazide; Drug Therapy, Combination; Humans; Levodopa; Male; Meperidine; Neurologic Examination; Parkinson Disease, Secondary; Substance Withdrawal Syndrome	1994
The effects of acute levodopa withdrawal on motor performance and dopaminergic receptor sensitivity in patients with Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry, 1993, Volume: 56, Issue:7 Topics: Aged; Apomorphine; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Psychomotor Performance; Receptors, Dopamine; Substance Withdrawal Syndrome	1993
Monoamines and their metabolites in plasma and lumbar cerebrospinal fluid of Chinese patients with Parkinson's disease. Journal of the neurological sciences, 1993, Volume: 116, Issue:2 Topics: Aged; Benserazide; Biogenic Monoamines; China; Chromatography, High Pressure Liquid; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Substance Withdrawal Syndrome	1993
End-of-dose dystonia in Parkinson's disease. Neurology, 1993, Volume: 43, Issue:10 Topics: Adult; Carbidopa; Dystonia; Humans; Infusions, Intravenous; Levodopa; Middle Aged; Parkinson Disease; Selegiline; Substance Withdrawal Syndrome	1993
Amantadine withdrawal and neuroleptic malignant syndrome. Neurology, 1993, Volume: 43, Issue:10 Topics: Amantadine; Bromocriptine; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	1993
Neuroleptic malignant syndrome postoperative onset due to levodopa withdrawal. Journal of clinical anesthesia, 1995, Volume: 7, Issue:8 Topics: Anesthesia; Antiparkinson Agents; Female; Humans; Levodopa; Middle Aged; Neuroleptic Malignant Syndrome; Neuromuscular Blocking Agents; Postoperative Complications; Substance Withdrawal Syndrome	1995
[Parkinson disease--problems in long-term treatment. Dopamine agonists optimize L-dopa therapy]. Fortschritte der Medizin, 1997, Feb-20, Volume: 115, Issue:5 Topics: Antiparkinson Agents; Dopamine Agonists; Drug Therapy, Combination; Humans; Levodopa; Lisuride; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Substance Withdrawal Syndrome	1997
The long-duration action of levodopa may be due to a postsynaptic effect. Clinical neuropharmacology, 1997, Volume: 20, Issue:5 Topics: Adult; Antiparkinson Agents; Dopamine Agents; Dopamine Agonists; Female; Humans; Indoles; Levodopa; Male; Middle Aged; Parkinson Disease; Receptors, Dopamine D2; Substance Withdrawal Syndrome; Time Factors	1997
The role of dopamine in the expression of morphine withdrawal. General pharmacology, 1998, Volume: 30, Issue:4 Topics: Adrenergic Agents; Analgesia; Analgesics, Opioid; Analysis of Variance; Animals; Apomorphine; Dopamine; Dopamine Agents; Dopamine Antagonists; Hypothermia; Levodopa; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Oxidopamine; Substance Withdrawal Syndrome	1998
[Malignant syndrome associated with disseminated intravascular coagulation and a high level of amylase in serum, followed by diabetic coma in an elderly patient with Parkinson's disease during L-dopa therapy]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1998, Volume: 35, Issue:2 Topics: Aged; Amylases; Diabetic Coma; Disseminated Intravascular Coagulation; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	1998
[Postoperative respiratory failure resulting from perioperative withdrawal of antiparkinsonian medications]. Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:1 Topics: Aged; Antiparkinson Agents; Humans; Levodopa; Male; Perioperative Care; Postoperative Complications; Respiratory Insufficiency; Substance Withdrawal Syndrome	1999
Neuroleptic malignant-like syndrome in an elderly patient caused by abrupt withdrawal of tolcapone, a-catechol-o-methyl transferase inhibitor. The American journal of medicine, 2000, Apr-15, Volume: 108, Issue:6 Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Antiparkinson Agents; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Confusion; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Nitrophenols; Substance Withdrawal Syndrome; Tolcapone	2000
Is there addiction to levodopa in patients with Parkinson's disease? Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:5 Topics: Aged; Antiparkinson Agents; Behavior, Addictive; Dose-Response Relationship, Drug; Humans; Levodopa; Male; Parkinson Disease; Quadriplegia; Substance Withdrawal Syndrome	2000
Neuroleptic malignant syndrome without neuroleptics. Singapore medical journal, 2001, Volume: 42, Issue:2 Topics: Antiparkinson Agents; Bromocriptine; Creatine Kinase; Diagnosis, Differential; Diagnostic Errors; Drug Therapy, Combination; Female; Humans; Levodopa; Middle Aged; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	2001
Switch-over from tolcapone to entacapone in severe Parkinson's disease patients. European neurology, 2001, Volume: 46, Issue:1 Topics: Aged; Antiparkinson Agents; Benzophenones; Catechols; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Mental Disorders; Middle Aged; Nitriles; Nitrophenols; Parkinson Disease; Substance Withdrawal Syndrome; Tolcapone	2001
Neuroleptic malignant syndrome in advanced Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2001, Volume: 16, Issue:5 Topics: Adult; Antiparkinson Agents; Humans; Levodopa; Male; Neuroleptic Malignant Syndrome; Parkinson Disease; Secondary Prevention; Severity of Illness Index; Substance Withdrawal Syndrome	2001
Sleep and behavioral changes possibly reflecting central receptor hypersensitivity following catecholamine synthesis inhibition in man. Acta psychiatrica Scandinavica, 1977, Volume: 56, Issue:3 Topics: Behavior; Bipolar Disorder; Dopamine; Humans; Levodopa; Norepinephrine; Receptors, Neurotransmitter; Sleep; Substance Withdrawal Syndrome; Tryptophan; Tyrosine	1977
[The effect of reserpine on the morphine abstinence syndrome in mice (author's transl)]. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1979, Volume: 34 Topics: 5-Hydroxytryptophan; Animals; Drug Antagonism; Humans; Levodopa; Male; Mice; Morphine Dependence; Reserpine; Substance Withdrawal Syndrome	1979
[On some dangerous withdrawals in neurology]. La Revue du praticien, 1979, Jan-01, Volume: 29, Issue:1 Topics: Anticoagulants; Barbiturates; Central Nervous System Diseases; Humans; Levodopa; Parasympatholytics; Substance Withdrawal Syndrome	1979
Time course of the effects of naturally occurring cannabinoids on morphine abstinence syndrome. Pharmacology, biochemistry, and behavior, 1978, Volume: 8, Issue:1 Topics: Amphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Dronabinol; Humans; Levodopa; Male; Mice; Morphine Dependence; Motor Activity; Naloxone; Substance Withdrawal Syndrome	1978
Suppression of ethanol withdrawal by dopamine. Experientia, 1976, Apr-15, Volume: 32, Issue:4 Topics: Animals; Dopamine; Ethanol; Haloperidol; Humans; Levodopa; Mice; Seizures; Substance Withdrawal Syndrome; Time Factors	1976
Pharmacological analysis of certain mechanisms of morphine addiction. Acta physiologica et pharmacologica Bulgarica, 1976, Volume: 2, Issue:2 Topics: Animals; Brain Chemistry; Diphenhydramine; Dopamine; Humans; Levodopa; Lysergic Acid Diethylamide; Male; Methysergide; Morphine Dependence; Norepinephrine; Rats; Reaction Time; Serotonin; Substance Withdrawal Syndrome; Time Factors	1976
Possible role of tetrahydroisoquinoline alkaloids in postalcohol intoxication states. Annals of the New York Academy of Sciences, 1976, Volume: 273 Topics: Alcoholic Intoxication; Alcoholism; Animals; Brain; Catecholamines; Chlordiazepoxide; Dopamine; Humans; Isoquinolines; Levodopa; Pyrazoles; Rats; Substance Withdrawal Syndrome	1976
Narcotic withdrawal like mouse jumping produced by amphetamine and L-DOPA. European journal of pharmacology, 1975, Volume: 30, Issue:1 Topics: Amphetamine; Animals; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Fluorometry; Haloperidol; Humans; Levodopa; Male; Mice; Motor Activity; Norepinephrine; Phentolamine; Pimozide; Substance Withdrawal Syndrome	1975
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain? Psychopharmacologia, 1975, Jun-19, Volume: 42, Issue:3 Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levodopa; Male; Morphine; Probenecid; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome	1975
Dopaminergic responsivity during cocaine abstinence: a pilot study. Psychiatry research, 1992, Volume: 43, Issue:1 Topics: Adult; Carbidopa; Cocaine; Dopamine Agents; Drug Combinations; Growth Hormone; Homovanillic Acid; Humans; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Prolactin; Receptors, Dopamine; Substance Withdrawal Syndrome; Substance-Related Disorders	1992
The effect of withdrawal of dopaminergic medication on simple and choice reaction time and the use of advance information in Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry, 1992, Volume: 55, Issue:12 Topics: Adult; Aged; Arousal; Attention; Choice Behavior; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Female; Humans; Levodopa; Male; Mental Processes; Middle Aged; Neuropsychological Tests; Parkinson Disease; Psychomotor Performance; Reaction Time; Substance Withdrawal Syndrome	1992
Apomorphine in malignant syndrome due to levodopa withdrawal. Italian journal of neurological sciences, 1992, Volume: 13, Issue:2 Topics: Aged; Apomorphine; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	1992
Dopaminergic activity and idiopathic edema. Hospital & community psychiatry, 1991, Volume: 42, Issue:3 Topics: Adult; Brain; Diuresis; Dopamine; Dyskinesia, Drug-Induced; Edema; Female; Galactorrhea; Haloperidol; Humans; Levodopa; Receptors, Dopamine; Substance Withdrawal Syndrome	1991
Chronic L-dopa treatment in the unilateral 6-OHDA rat: evidence for behavioral sensitization and biochemical tolerance. Brain research, 1991, Dec-24, Volume: 568, Issue:1-2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Carbidopa; Corpus Striatum; Denervation; Drug Tolerance; Functional Laterality; Homovanillic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome	1991
Effects of withdrawal of antiparkinson medication on gait and clinical score in the Parkinson patient. Acta neurologica Scandinavica, 1991, Volume: 84, Issue:1 Topics: Aged; Antiparkinson Agents; Bromocriptine; Disability Evaluation; Drug Therapy, Combination; Female; Gait; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Substance Withdrawal Syndrome	1991
Neuroleptic malignant syndrome complicating levodopa withdrawal. The Medical journal of Australia, 1991, Jul-01, Volume: 155, Issue:1 Topics: Aged; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	1991
Neuroleptic malignant syndrome without neuroleptics. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:6 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Carbidopa; Depressive Disorder; Drug Combinations; Drug Therapy, Combination; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome; Tranylcypromine; Tryptophan	1990
A pilot trial of levodopa/carbidopa in early cocaine abstinence. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:6 Topics: Adult; Arousal; Carbidopa; Cocaine; Drug Therapy, Combination; Humans; Levodopa; Pilot Projects; Substance Withdrawal Syndrome; Substance-Related Disorders	1990
Illicit drug use in strength athletes. The British journal of psychiatry : the journal of mental science, 1989, Volume: 154 Topics: Adult; Anabolic Agents; Diagnosis, Differential; Humans; Levodopa; Male; Physical Education and Training; Substance Withdrawal Syndrome	1989
Levodopa addiction. A case study. Acta psychiatrica Scandinavica, 1988, Volume: 78, Issue:3 Topics: Adult; Dermatitis, Seborrheic; Dose-Response Relationship, Drug; Female; Humans; Levodopa; Muscle Rigidity; Paranoid Disorders; Parkinson Disease, Secondary; Psychoses, Substance-Induced; Risk Factors; Substance Withdrawal Syndrome; Substance-Related Disorders	1988
Pathophysiology of L-dopa-induced abnormal involuntary movements. Psychopharmacology. Supplementum, 1985, Volume: 2 Topics: Brain; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Humans; Levodopa; Neural Pathways; Parkinson Disease; Receptors, Dopamine; Spiperone; Substance Withdrawal Syndrome; Substantia Nigra; Synapses; Synaptic Transmission	1985
Social, motor, and autonomic signs of morphine withdrawal: differential sensitivities to catecholaminergic drugs in mice. Psychopharmacology, 1988, Volume: 96, Issue:4 Topics: Animals; Apomorphine; Autonomic Nervous System; Catecholamines; Clonidine; Cocaine; Dextroamphetamine; Levodopa; Mice; Mice, Inbred Strains; Morphine Dependence; Psychomotor Performance; Reaction Time; Social Behavior; Substance Withdrawal Syndrome	1988
Neuroleptic malignant syndrome in striatonigral degeneration. The British journal of psychiatry : the journal of mental science, 1988, Volume: 153 Topics: Aged; Corpus Striatum; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome; Substantia Nigra	1988
Dystonia in Parkinson's disease: clinical and pharmacological features. Annals of neurology, 1988, Volume: 23, Issue:1 Topics: Adult; Aged; Circadian Rhythm; Dose-Response Relationship, Drug; Dystonia; Humans; Injections, Intravenous; Levodopa; Middle Aged; Parkinson Disease; Substance Withdrawal Syndrome	1988
Stepwise detoxification from cocaine. A promising regimen. Postgraduate medicine, 1988, Volume: 84, Issue:2 Topics: Adolescent; Adult; Amantadine; Bromocriptine; Cocaine; Desipramine; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine	1988
Successful treatment of levodopa-induced myoclonus and levodopa withdrawal-induced neuroleptic malignant syndrome. A case report. Clinical neuropharmacology, 1988, Volume: 11, Issue:3 Topics: Aged; Cyproheptadine; Humans; Levodopa; Male; Methysergide; Myoclonus; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	1988
Sudden confusion with levodopa withdrawal. Movement disorders : official journal of the Movement Disorder Society, 1987, Volume: 2, Issue:3 Topics: Cognition Disorders; Confusion; Humans; Levodopa; Parkinson Disease; Parkinson Disease, Secondary; Substance Withdrawal Syndrome	1987
[Phenomenon of inverted rotation in spastic torticollis]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:3 Topics: Adult; Brain; Carbidopa; Drug Combinations; Female; Humans; Levodopa; Muscle Spasticity; Receptors, Dopamine; Rotation; Substance Withdrawal Syndrome; Torticollis	1986
Levodopa withdrawal and the neuroleptic malignant syndrome. Postgraduate medical journal, 1986, Volume: 62, Issue:729 Topics: Humans; Levodopa; Neuroleptic Malignant Syndrome; Substance Withdrawal Syndrome	1986
Levodopa withdrawal syndrome identical to neuroleptic malignant syndrome. Postgraduate medical journal, 1986, Volume: 62, Issue:723 Topics: Female; Humans; Levodopa; Middle Aged; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	1986
Transient levodopa withdrawal in Parkinson's disease. Clinical pharmacy, 1987, Volume: 6, Issue:1 Topics: Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Substance Withdrawal Syndrome	1987
Temporary levodopa withdrawal. The New England journal of medicine, 1986, Mar-27, Volume: 314, Issue:13 Topics: Drug Administration Schedule; Humans; Levodopa; Parkinson Disease; Substance Withdrawal Syndrome	1986
The role of salsolinol in alcohol intake and withdrawal. Progress in clinical and biological research, 1985, Volume: 183 Topics: Acetaldehyde; Alcoholism; Ethanol; Humans; Isoquinolines; Levodopa; Male; Middle Aged; Substance Withdrawal Syndrome; Time Factors	1985
A neuroleptic malignantlike syndrome due to levodopa therapy withdrawal. JAMA, 1985, Nov-15, Volume: 254, Issue:19 Topics: Aged; Humans; Levodopa; Male; Middle Aged; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome	1985