Page last updated: 2024-08-17

levodopa and Aging

levodopa has been researched along with Aging in 181 studies

Research

Studies (181)

Timeframe	Studies, this research(%)	All Research%
pre-1990	59 (32.60)	18.7374
1990's	54 (29.83)	18.2507
2000's	33 (18.23)	29.6817
2010's	32 (17.68)	24.3611
2020's	3 (1.66)	2.80

Authors

Authors	Studies
Kleppe, R; Ruoff, P; Waheed, Q	1
Bhidayasiri, R; Phokaewvarangkul, O; Virameteekul, S	1
D'Amelio, M; Giacalone, E; Keller, F; Krashia, P; La Barbera, L; Lupascu, CA; Migliore, M; Nobili, A; Renzi, M; Spoleti, E	1
Hanajima, R; Ohminami, S; Shimizu, T; Shirota, Y; Tanaka, N; Terao, Y; Tsuji, S; Tsutsumi, R; Ugawa, Y	1
Bugdol, M; Czernek, M; Derejczyk, J; Kapko, W; Kawa, J; Marcisz, C; Seiffert, P; Stępień-Wyrobiec, O; Szymszal, J; Torbus, A	1
Donsante, C; Fan, X; Harrast, P; Hess, EJ; Jinnah, HA; Joers, V; Rose, SJ; Tansey, MG	1
MacDonald, PA; Seergobin, KN; Vo, A	1
Ahn, JH; Cho, JW; Cho, KR; Kim, M; Lee, JI; Park, JH; Park, S; Youn, J	1
Albrecht, F; Ballarini, T; Bezdicek, O; Jech, R; Mueller, K; Roth, J; Růžička, E; Růžička, F; Schroeter, ML; Vymazal, J	1
Bishop, C; Deak, T; Lanza, K; Perkins, AE	1
Chowdhury, R; Dayan, P; Dolan, RJ; Düzel, E; Guitart-Masip, M; Huys, Q; Lambert, C	1
Shohamy, D; Wimmer, GE	1
Müller, T	1
Martey, J; Rajabally, YA	1
Anderson, W; Badugu, S	1
Li, B; Li, Y; Sun, Y; Wu, Y; Yang, J; Yu, J	1
Backer, F; Govind, P; James, P; Kishore, A; Meunier, S; Popa, T; Pradeep, S; Varughese Chacko, L; Yahia-Cherif, L	1
Collier, TJ; Gebremedhin, KG; O'Malley, J; Paumier, KL; Rademacher, DJ; Sisson, KA; Sortwell, CE; Stancati, JA; Steece-Collier, K	1
Horvath, S; Ritz, BR	1
Alegre-Abarrategui, J; Bannerman, DM; Bolam, JP; Brimblecombe, K; Cioroch, M; Connor-Robson, N; Cragg, SJ; Deltheil, T; Dodson, PD; Exley, R; Kaufmann, AK; Magill, PJ; Potgieter, D; Sloan, M; Threlfell, S; Wade-Martins, R; Wallings, R	1
Bez, F; Cenci, MA; Francardo, V	1
Rajput, AH; Rajput, EF	1
Andersen, AD; Binzer, M; Blaabjerg, M; Gramsbergen, JBP; Kamal, A; Kjaer, TW; Stenager, E; Thagesen, H	1
Almeida, L; Falcão, A; Fernandes-Lopes, C; Loureiro, AI; Nunes, T; Rocha, JF; Soares-da-Silva, P; Vaz-da-Silva, M; Wright, L	1
Cantero, M; Cediel, R; Contreras, J; Montoliu, L; Murillo-Cuesta, S; Varela-Nieto, I; Zurita, E	1
Abdel Wahab, Z; El-Moursy, SA; Rashed, L; Shawky, HM	1
Allen, E; Carlson, KM; Cavanaugh, JE; Zigmond, MJ	1
Hamamoto, M; Katayama, Y; Kumagai, T; Nagayama, H; Nishimura, S; Nishiyama, Y; Tsukamoto, K; Ueda, M	1
Brunk, UT; Dunlop, RA; Rodgers, KJ	1
Fink, GR; Lie, CH; Onur, ÖA; Piefke, M; Thiel, CM	1
Abbs, JH; Bendlin, BB; Brooks, BR; Brown, WD; Chung, MK; Dejesus, OT; Dogan, S; Gallagher, CL; Holden, JE; Johnson, SC; Konopacki, RA; Nickles, RJ; Oakes, TR; Pyzalski, RW; Xu, G	1
Pruett, BS; Salvatore, MF	1
Ionov, ID; Severtsev, NN	1
Kulkarni, N; Ledeen, RW; Lu, ZH; Wu, G	1
Butler, SG; Feng, X; Kritchevsky, SB; Leng, I; Xu, Z; Zhang, T	1
Bunzeck, N; Chowdhury, R; Dolan, RJ; Düzel, E; Guitart-Masip, M	1
Gawel, D; Gawel, M; Jamrozik, Z; Kaminska, A; Rowińska-Marcińska, K; Slawek, J; Szmidt-Salkowska, E	1
Fukumoto, D; Harada, N; Kakiuchi, T; Nishiyama, S; Satoh, K; Tsukada, H	1
Nieoullon, A	1
Froelick, GJ; Kim, DS; Palmiter, RD	1
Ogawa, N	1
Innis, SM; Ng, KF	1
Giladi, N; Korczyn, AD; Merims, D; Peretz, C; Shabtai, H; Weizman, N	1
Brown, AM; Colbran, RJ; Deutch, AY	1
Bottiglieri, T; Diaz-Arrastia, R; Greenberg, SM; Growdon, JH; Gurol, ME; Hyman, BT; Irizarry, MC; Locascio, JJ; Raju, S; Tennis, M	1
Staup, MA; Stehouwer, DJ	1
Li, T; Malapani, C; Rakitin, BC; Scarmeas, N; Stern, Y	1
Asada, T; Ito, H; Nozaki, S; Ota, M; Seki, C; Suhara, T; Yasuno, F	1
Bae, E; Bang, S; Chun, B; Chung, J; Kang, J; Kim, J; Lee, S; Lee, Y; Paik, D	1
Colebrooke, RE; Emson, PC; Humby, T; Lynch, PJ; McGowan, DP; Xia, J	1
Abreu, P; Afonso-Oramas, D; Barroso-Chinea, P; Cruz-Muros, I; González, MC; Hernández, TG; Rodríguez, M	1
Mash, DC; Papapetropoulos, S	1
Pinho, MJ; Serrão, MP; Soares-da-Silva, P	1
Erginöz, E; Ertan, S; Ertan, T; Kiziltan, G; Ozekmekçi, S	1
Chen, JJ; Fernandez, HH	1
Levy, G	1
Segawa, M	1
Breitenstein, C; Floel, A; Knecht, S; Lorenzen, A; Roesser, N; Vomhof, P	1
Azulay, JP; Bourdeix, I; Durif, F; Rerat, K; Rogez, R; Tranchant, C	1
Grahovska, T; Konstantinova, E; Petkov, VD; Petkov, VV	1
Jellinger, K; Riederer, P; Tomonaga, M	1
Itoh, H	1
Fisman, M	1
Walker, RF	1
Masturzo, P; Murialdo, G; Nappi, G; Polleri, A; Sances, G; Savoldi, F	1
Frackowiak, RS; Gibbs, JM; Jones, T; Lammertsma, AA; Leenders, KL	1
Wilke, WL	1
Praznikov, VP	1
Parkes, JD	1
Commissiong, JW	2
Aikawa, E; Kawasaki, K; Mato, M; Ookawara, S	1
Buterbaugh, GG; London, ED; Vocci, FJ; Waller, SB	1
Cooper, RL; Linnoila, M	2
Forman, LJ; Meites, J; Miki, N; Sonntag, WE	1
Porter, JC; Reymond, MJ	1
Houlihan, G; Miller, ST; Nerder, LJ; Papavasiliou, PS; Rao, SN; Stevens, JM; Thal, LJ	1
Osuide, G; Wambebe, C	1
Steger, RW	1
Clough, CG; Mendoza, M; Yahr, MD	1
Bone, AH; Taufek, HR	1
Dregits, DP; Erinoff, L; Levine, TE; Seiden, LS	1
Anisimov, VN; Dilman, VM	1
Cano, J; de la Roza, C; Machado, A; Venero, JL	1
Cano, J; Machado, A; Venero, JL	2
Fernandes, MH; Guimarães, JT; Pestana, M; Soares-da-Silva, P; Vieira-Coelho, MA	1
Chatel, DM; Dahdal, WY; Franson, KL; Grossberg, GT; Hay, DP; Kotegal, S; Mirza, WU; Neppe, V; Szwabo, PA	1
McCrea, AE; Stehouwer, DJ; Van Hartesveldt, C	2
Ghijsels, E; Moons, L; van Gils, J; Vandesande, F	1
Dopico, AM; Zieher, LM	1
Knoll, J	1
Bowes, SG; Charlett, A; Dickins, J; Dobbs, RJ; Dobbs, SM; Frith, C; Henley, M	1
Falk, M; Künig, G; Neubauer, M; Ransmayr, G; Wagner, M	1
Battistin, L; Cagnin, A; Chierichetti, F; Dam, M; Fabbri, M; Ferlin, G; Pizzolato, G; Rossato, A	1
Albani, M; Grigoriadis, N; Guiba-Tziampiri, O; Parashos, SA; Simeonidou, C	1
Aihara, Y; Kanazawa, I; Murata, M; Yamada, S; Yamanouchi, H	1
Bulygina, VV; Markel', AL; Maslova, LN; Naumenko, EV; Shishkina, GT	1
Bodis-Wollner, I; Tagliati, M; Yahr, MD	1
McEwen, ML; Stehouwer, DJ; Van Hartesveldt, C	1
Kurth, MC	1
Camicioli, R; Ganzini, L; Young, BK	1
Playfer, JR	1
Caffarri, G; Capretti, L; Chiodera, P; Cigarini, C; Coiro, V; Gramellini, D; Necchi Ghiri, S; Volpi, R	1
Martí-Massó, JF	1
Adler, CH; Atkinson, EJ; Boylan, KB; Caviness, JN; Finton, MJ; Goerss, SJ; Graff-Radford, NR; Kall, BA; Lucas, JA; Turk, MF; Uitti, RJ; Wharen, RE	1
Mark, MH; Sage, JI	1
Quinn, NP	1
Andersen, SL; Dumont, NL; Teicher, MH	1
Barbato, L; Berardelli, A; Nordera, G; Ruggieri, S; Stocchi, F	1
Bertorello, AM; Finkel, Y; Soares-Da-Silva, P; Teixeira, VA; Vieira-Coelho, MA	1
Ingvarsson, PE; Johnels, B; Olsson, T; Steg, G	1
Guimaraes, JT; Hussain, T; Kansra, V; Lokhandwala, MF; Pestana, M; Serrao, MP; Soares-Da-Silva, P; Vieira-Coelho, MA	1
Peng, Y; Shui, H; Tsai, Y; Wu, R	1
Chang, CK; Cheng, JT; Chi, TC; Lee, JJ; Liu, IM; Yu, HJ	1
Diroma, C; Fraddosio, A; Iliceto, G; Lamberti, S; Moramarco, A; Palagano, G; Zenzola, A	1
Bettencourt, P; Cerqueira-Gomes, M; Correia, F; Ferreira, A; Martins, L; Pestana, M; Serrão, P; Soares-Da-Silva, P	1
Hussain, T; Lokhandwala, MF; Serrão, P; Soares-da-Silva, P; Vieira-Coelho, MA	1
Kleinow, J; Ramig, LO; Smith, A	1
DeJesus, OT; Holden, JE; Nickles, RJ; Roberts, AD; Shelton, SE	1
Arafah, BM; Biller, BM; Bonert, V; Chipman, JJ; Cook, DM; Hartman, ML; Kleinberg, DL; Samuels, MH; Stavrou, S; Zagar, A	1
Hickey, MA; Morton, AJ; Reynolds, GP	1
de Vries, JA; Fremouw-Ottevangers, DC; Muskiet, FA; van der Meulen, J; Wolthers, BG	1
Blog, FB; Gilchrest, BA; Szabo, G	1
Janoff, AS; Rosenberg, B	1
Anisimov, VN; Dil'man, VM	1
Berrios, N; Marshall, JF	1
Matsuzawa, T	1
Brandt, S; Cooper, RL; Linnoila, M	1
Hendricks, SE; Lehman, JR; McArthur, DA	1
Anisimov, VN; Dmitrievskaia, AIu; Gracheva, GM; Il'in, AP; Pozdeev, VK	1
Alper, A; Dougher, GJ; Finch, CE; Hody, G; Jonec, V; Morton-Smith, W; Walker, JP	1
Meites, J; Riegle, GD	1
Fernandes, MH; Soares-da-Silva, P	2
Horak, FB; Nashner, LM; Nutt, JG	1
Coper, H; Hausmanowa-Petrusewicz, I; Kaminska, A; Ossowska, K; Schulze, G; Wolfarth, S	1
Appel, SH; Bostwick, JR; Le, WD	1
Allain, H; Bentue-Ferrer, D; Decombe, R; Lemaitre, MH; Martinet, JP; Milon, D	1
Angelberger, P; Brücke, T; Deecke, L; Küfferle, B; Müller, C; Podreka, I; Topitz, A; Wenger, S	1
Dluzen, D; McDermott, J	1
Drucker-Colín, R; García-Hernández, F	1
Greenspan, SL; Rowe, JW; Sparrow, D	1
Joyce, JN; Neal, BS	1
Bhatt, MH; Calne, DB; Martin, WR; Pate, BD; Ruth, TJ; Snow, BJ	1
Dluzen, DE; McDermott, JL	1
Da Prada, M	1
Inoue, S; Numata, K; Saito, M; Shiraki, J; Shishido, T; Takamura, Y; Tanaka, K	1
Flaster, E; Kostic, V; Przedborski, S; Sternic, N	1
Bando, H; Saito, S; Takada, Y; Yamasaki, R; Zhang, C	1
Garcia-Rill, E; Iwahara, T; Skinner, RD; Van Hartesveldt, C	1
Dluzen, DE; McDermott, JL; Ramirez, VD	2
Danilov, AA; Grigor'iants, RA; Kiseleva, ZM; Mukharliamov, NM	1
Buu, NT; Debinski, W	1
Bowes, SG; Deshmukh, AA; Dobbs, RJ; Dobbs, SM; Hughes, JR; Leeman, AL; Nicholson, PW; O'Neill, CJ	1
Markel, AL; Maslova, LN; Naumenko, EV	1
Ianovich, LA; Kuznetsova, SM; Man'kovskiĭ, NB; Red'ko, LA	1
Gross, J; Horvath, G; Lun, A; Nagy, I; Szuecz, L	1
Garty, M; Goldstein, DS; Kopin, IJ; Stull, R	1
Diamond, SG; Hoehn, MM; Markham, CH; McDowell, FH; Muenter, MD	1
Everest, H; George, CF; Monks, K; Renwick, AG; Robertson, DR; Waller, DG; Wood, ND	1
Greer, M	1
Leathwood, PD	1
Atsumi, F; Iwamoto, K; Matsushita, T; Watanabe, J; Yamada, M	1
Konstantinova, E; Petkov, VD; Petkov, VV; Popova, J	1
Reed, JD; Schneider, EL	1
Gancher, ST; Nutt, JG; Woodward, W	1
LeWitt, PA	1
Mortimer, JA	1
Gottfries, CG	1
Ribera Casado, JM	1
Ermini, M; Finch, CE; Flurkey, K; Randall, PK; Sinha, YN	1
Atsumi, F; Iwamoto, K; Watanabe, J	1
Gordienko, NI; Markel', AL; Maslova, LN; Naumenko, EV	1
Dontsov, VI	1
De Keyser, J	1
Calne, DB; Jaffe, M; Larsen, TA; LeWitt, PA; Newman, RP	1
Hylka, VW; Meites, J; Sonntag, WE	1

Reviews

19 review(s) available for levodopa and Aging

Article	Year
Detoxification and antioxidative therapy for levodopa-induced neurodegeneration in Parkinson's disease. Expert review of neurotherapeutics, 2013, Volume: 13, Issue:6 Topics: Aging; Animals; Antioxidants; Antiparkinson Agents; Disease Progression; Dopamine Agonists; Humans; Inactivation, Metabolic; Levodopa; Nerve Degeneration; Oxidative Stress; Parkinson Disease	2013
Dopamine and the regulation of cognition and attention. Progress in neurobiology, 2002, Volume: 67, Issue:1 Topics: Adult; Aged; Aging; Animals; Antiparkinson Agents; Attention; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Basal Ganglia; Child; Cognition; Cognition Disorders; Dopamine; Dopamine Agonists; Humans; Levodopa; Limbic System; Middle Aged; Models, Neurological; Models, Psychological; Parkinson Disease; Phylogeny; Receptors, Dopamine; Schizophrenic Psychology	2002
[Etiology and physiopathology of patients with parkinson's disease]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2003, Aug-10, Volume: 92, Issue:8 Topics: Aging; Dopamine; Dopamine Agonists; Free Radicals; Humans; Levodopa; Ligases; Mutation; Nerve Tissue Proteins; Parkinson Disease; Synucleins; Ubiquitin-Protein Ligases	2003
Community and long-term care management of Parkinson's disease in the elderly: focus on monoamine oxidase type B inhibitors. Drugs & aging, 2007, Volume: 24, Issue:8 Topics: Aged; Aging; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Catechol O-Methyltransferase Inhibitors; Dopamine Agonists; Homes for the Aged; Humans; Indans; Levodopa; Monoamine Oxidase Inhibitors; Nursing Homes; Parkinson Disease; Selegiline	2007
The relationship of Parkinson disease with aging. Archives of neurology, 2007, Volume: 64, Issue:9 Topics: Aging; Antiparkinson Agents; Cognition Disorders; Dementia; Disease Progression; Gait; Humans; Levodopa; Parkinson Disease; Posture	2007
Drug-induced tardive dyskinesia. Current developments in psychopharmacology, 1981, Volume: 6 Topics: Aging; Antipsychotic Agents; Basal Ganglia Diseases; Diagnosis, Differential; Dyskinesia, Drug-Induced; Humans; Huntington Disease; Levodopa; Psychotic Disorders; Racial Groups; Sex Factors	1981
Clinical pharmacology of senile dementia. Progress in neuro-psychopharmacology, 1981, Volume: 5, Issue:5-6 Topics: Aged; Aging; Anticoagulants; Arginine Vasopressin; Brain; Choline; Dementia; Dihydroergotoxine; Free Radicals; Glucose; Humans; Levodopa; Neurotransmitter Agents; Vasodilator Agents; Xanthinol Niacinate	1981
Positron emission tomography of the brain: new possibilities for the investigation of human cerebral pathophysiology. Progress in neurobiology, 1984, Volume: 23, Issue:1-2 Topics: Aging; Amino Acids; Arterial Occlusive Diseases; Brain; Brain Ischemia; Brain Neoplasms; Carotid Artery Diseases; Cerebral Infarction; Cerebrovascular Disorders; Dementia; Epilepsy; Fluorine; Forecasting; Homeostasis; Humans; Huntington Disease; Isotopes; Levodopa; Mental Disorders; Models, Biological; Neurology; Oxygen Radioisotopes; Parkinson Disease; Radioisotopes; Receptors, Drug; Reference Values; Respiration; Tomography, Emission-Computed	1984
Drug-induced seizures in the elderly. Causative agents and optimal management. Drugs & aging, 1995, Volume: 7, Issue:1 Topics: Aging; Anti-Bacterial Agents; Anti-Infective Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Central Nervous System Agents; Histamine H2 Antagonists; Humans; Lactams; Levodopa; Seizures; Substance Withdrawal Syndrome; Theophylline	1995
The pharmacological basis of the beneficial effects of (-)deprenyl (selegiline) in Parkinson's and Alzheimer's diseases. Journal of neural transmission. Supplementum, 1993, Volume: 40 Topics: Aging; Alzheimer Disease; Animals; Avoidance Learning; Catalase; Corpus Striatum; Drug Therapy, Combination; Learning; Levodopa; Male; Neurons; Parkinson Disease; Rats; Selegiline; Substantia Nigra; Superoxide Dismutase	1993
Using liquid levodopa in the treatment of Parkinson's disease. A practical guide. Drugs & aging, 1997, Volume: 10, Issue:5 Topics: Administration, Oral; Aging; Antiparkinson Agents; Central Nervous System; Gastric Emptying; Humans; Injections, Intravenous; Intestinal Absorption; Levodopa; Parkinson Disease; Solutions	1997
Neuropsychiatric adverse effects of antiparkinsonian drugs. Characteristics, evaluation and treatment. Drugs & aging, 1997, Volume: 10, Issue:5 Topics: Aging; Akathisia, Drug-Induced; Amantadine; Antiparkinson Agents; Antipsychotic Agents; Cholinergic Antagonists; Delirium; Dementia; Depression; Dopamine Agonists; Electroconvulsive Therapy; Humans; Levodopa; Memantine; Monoamine Oxidase Inhibitors; Psychoses, Substance-Induced; Risk Factors; Serotonin Antagonists	1997
Parkinson's disease. Postgraduate medical journal, 1997, Volume: 73, Issue:859 Topics: Aged; Aging; Antiparkinson Agents; Humans; Levodopa; Parkinson Disease; Parkinson Disease, Secondary	1997
[Drug-related motor disorders in aged people]. Revista de neurologia, 1997, Volume: 25 Suppl 1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Aging; Antiparkinson Agents; Antipsychotic Agents; Calcium Channel Blockers; Humans; Levodopa; Psychomotor Disorders	1997
Pharmacokinetics of continuous-release carbidopa/levodopa. Clinical neuropharmacology, 1994, Volume: 17 Suppl 2 Topics: Aging; Antiparkinson Agents; Area Under Curve; Blood-Brain Barrier; Carbidopa; Delayed-Action Preparations; Drug Combinations; Gastric Emptying; Humans; Levodopa; Solubility	1994
Sleep disorders in Parkinson's disease. Journal of neurology, 1998, Volume: 245 Suppl 1 Topics: Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Clinical Trials as Topic; Humans; Levodopa; Middle Aged; Motor Activity; Muscle, Skeletal; Parkinson Disease; Respiration; Sleep Wake Disorders	1998
New approaches to the treatment of age-related brain disorders. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1991, Volume: 18, Issue:3 Suppl Topics: Aging; Alzheimer Disease; Benserazide; Benzophenones; Catechol O-Methyltransferase Inhibitors; Drug Combinations; Enzyme Inhibitors; Humans; Levodopa; Monoamine Oxidase Inhibitors; Nitrophenols; Parkinson Disease; Picolinic Acids; Tolcapone	1991
[Dopaminergic mechanisms of brain aging (a review of the literature)]. Vrachebnoe delo, 1989, Issue:9 Topics: Aging; Animals; Brain; Dopamine; Humans; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Receptors, Dopamine	1989
Life extension. The New England journal of medicine, 1985, May-02, Volume: 312, Issue:18 Topics: Aged; Aging; Animals; Antioxidants; Dehydroepiandrosterone; Diet; Energy Intake; Ethics, Medical; Female; Free Radicals; Humans; Hypophysectomy; Immunocompetence; Levodopa; Life Expectancy; Longevity; Male; Meclofenoxate; Mice; Middle Aged; Models, Biological; Physical Exertion; Procaine; Superoxide Dismutase; Ubiquinone	1985

Trials

12 trial(s) available for levodopa and Aging

Article	Year
Dopamine restores reward prediction errors in old age. Nature neuroscience, 2013, Volume: 16, Issue:5 Topics: Adult; Aged; Aging; Alkaloids; Brain; Conditioning, Operant; Dopamine Agents; Double-Blind Method; Female; Humans; Image Processing, Computer-Assisted; Levodopa; Magnetic Resonance Imaging; Male; Oxygen; Reinforcement, Psychology; Reward; Time Factors; Young Adult	2013
Modulatory effects of levodopa on cognitive control in young but not in older subjects: a pharmacological fMRI study. Journal of cognitive neuroscience, 2011, Volume: 23, Issue:10 Topics: Adult; Aged; Aging; Analysis of Variance; Brain Mapping; Catechol O-Methyltransferase; Cognition; Dopamine Agents; Double-Blind Method; Female; Functional Laterality; Humans; Image Processing, Computer-Assisted; Levodopa; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Oxygen; Prefrontal Cortex; Reaction Time; Young Adult	2011
Dopamine modulates episodic memory persistence in old age. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Oct-10, Volume: 32, Issue:41 Topics: Aged; Aging; Cohort Studies; Cross-Over Studies; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hippocampus; Humans; Levodopa; Magnetic Resonance Imaging; Male; Memory, Episodic; Photic Stimulation	2012
Levodopa improves skilled hand functions in the elderly. The European journal of neuroscience, 2008, Volume: 27, Issue:5 Topics: Adult; Aged; Aging; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Hand; Heart Rate; Humans; Levodopa; Male; Middle Aged; Motor Skills	2008
Effect of age and disease duration on parkinsonian motor scores under levodopa therapy. Journal of neural transmission. Parkinson's disease and dementia section, 1995, Volume: 9, Issue:2-3 Topics: Adult; Aged; Aging; Antiparkinson Agents; Bromocriptine; Disease Progression; Female; Gait; Humans; Levodopa; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Psychomotor Performance; Tremor	1995
Striatal dopamine D2 receptor alterations and response to L-DOPA in Parkinson's disease. A [123I]IBZM SPET study. Advances in neurology, 1996, Volume: 69 Topics: Adult; Age of Onset; Aged; Aging; Antiparkinson Agents; Disease Progression; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Middle Aged; Neostriatum; Parkinson Disease; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon	1996
Altered neuroendocrine control of GH secretion in normal women of advanced reproductive age. The journals of gerontology. Series A, Biological sciences and medical sciences, 1997, Volume: 52, Issue:4 Topics: Adult; Aging; Dopamine Agonists; Female; GABA Agonists; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Levodopa; Middle Aged; Neurosecretory Systems; Reference Values; Reproduction; Serotonin Receptor Agonists; Sumatriptan; Valproic Acid	1997
Sleep disorders in Parkinson's disease. Journal of neurology, 1998, Volume: 245 Suppl 1 Topics: Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Clinical Trials as Topic; Humans; Levodopa; Middle Aged; Motor Activity; Muscle, Skeletal; Parkinson Disease; Respiration; Sleep Wake Disorders	1998
Sensitivity and specificity of six tests for the diagnosis of adult GH deficiency. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:5 Topics: Adult; Aged; Aging; Arginine; Body Mass Index; Diagnostic Techniques, Endocrine; Drug Combinations; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Levodopa; Male; Metabolic Diseases; Middle Aged; Sensitivity and Specificity; Sex Characteristics; Stimulation, Chemical	2002
Parkinsonian abnormality of foot strike: a phenomenon of ageing and/or one responsive to levodopa therapy? British journal of clinical pharmacology, 1990, Volume: 29, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Female; Gait; Humans; Levodopa; Male; Middle Aged; Parkinson Disease	1990
The effect of age on the pharmacokinetics of levodopa administered alone and in the presence of carbidopa. British journal of clinical pharmacology, 1989, Volume: 28, Issue:1 Topics: Administration, Oral; Adult; Aged; Aging; Carbidopa; Drug Interactions; Female; Humans; Injections, Intravenous; Levodopa; Male	1989
Motor function in the normal aging population: treatment with levodopa. Neurology, 1985, Volume: 35, Issue:4 Topics: Aged; Aging; Carbidopa; Dopamine; Drug Combinations; Humans; Levodopa; Middle Aged; Movement; Movement Disorders; Parkinson Disease	1985

Other Studies

151 other study(ies) available for levodopa and Aging

Article	Year
DOPA Homeostasis by Dopamine: A Control-Theoretic View. International journal of molecular sciences, 2021, Nov-28, Volume: 22, Issue:23 Topics: Aging; Dihydroxyphenylalanine; Dopamine; Homeostasis; Humans; Levodopa; Models, Neurological; Oxidative Stress; Tyrosine 3-Monooxygenase	2021
Profiling the most elderly parkinson's disease patients: Does age or disease duration matter? PloS one, 2021, Volume: 16, Issue:12 Topics: Age Factors; Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Case-Control Studies; Clinical Protocols; Comorbidity; Disease Progression; Geriatrics; Humans; Levodopa; Middle Aged; Parkinson Disease; Patient Acuity; Thailand	2021
Early derailment of firing properties in CA1 pyramidal cells of the ventral hippocampus in an Alzheimer's disease mouse model. Experimental neurology, 2022, Volume: 350 Topics: Action Potentials; Aging; Alzheimer Disease; Animals; CA1 Region, Hippocampal; Dopamine Agents; Dopaminergic Neurons; Electrophysiological Phenomena; Female; Levodopa; Male; Mice; Mice, Transgenic; Potassium Channels; Pyramidal Cells; Sodium Channels; Tyrosine 3-Monooxygenase; Ventral Tegmental Area	2022
Effects of L-DOPA on quadripulse magnetic stimulation-induced long-term potentiation in older adults. Neurobiology of aging, 2019, Volume: 84 Topics: Aged; Aging; Cross-Over Studies; Double-Blind Method; Humans; Levodopa; Long-Term Potentiation; Neuronal Plasticity; Transcranial Magnetic Stimulation	2019
Frailty phenotype and the role of levodopa challenge test in geriatric inpatients with mild parkinsonian signs. Biogerontology, 2017, Volume: 18, Issue:4 Topics: Age Factors; Aged; Aged, 80 and over; Aging; Benserazide; Case-Control Studies; Cross-Sectional Studies; Dopamine; Dopamine Agents; Drug Combinations; Female; Frail Elderly; Frailty; Geriatric Assessment; Geriatrics; Humans; Inpatients; Levodopa; Male; Parkinson Disease; Phenotype; Poland; Predictive Value of Tests; Prevalence; Severity of Illness Index	2017
Parkinsonism without dopamine neuron degeneration in aged l-dopa-responsive dystonia knockin mice. Movement disorders : official journal of the Movement Disorder Society, 2017, Volume: 32, Issue:12 Topics: Aging; Analysis of Variance; Animals; Antiparkinson Agents; Dopamine Agents; Dopamine beta-Hydroxylase; Dopamine Plasma Membrane Transport Proteins; Dystonic Disorders; Female; Levodopa; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Parkinsonian Disorders; Tyrosine 3-Monooxygenase	2017
Independent effects of age and levodopa on reversal learning in healthy volunteers. Neurobiology of aging, 2018, Volume: 69 Topics: Adult; Aged; Aging; Carbidopa; Cross-Over Studies; Dopamine Agonists; Double-Blind Method; Drug Combinations; Humans; Levodopa; Punishment; Reversal Learning; Reward; Young Adult	2018
Bilateral subthalamic deep brain stimulation is an effective and safe treatment option for the older patients with Parkinson's disease. Clinical neurology and neurosurgery, 2018, Volume: 173 Topics: Adult; Aged; Aging; Brain; Deep Brain Stimulation; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Subthalamic Nucleus; Treatment Outcome	2018
Regional gray matter changes and age predict individual treatment response in Parkinson's disease. NeuroImage. Clinical, 2019, Volume: 21 Topics: Age Factors; Aged; Aging; Antiparkinson Agents; Brain; Female; Gray Matter; Humans; Levodopa; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Predictive Value of Tests; Treatment Outcome	2019
Late aging-associated increases in L-DOPA-induced dyskinesia are accompanied by heightened neuroinflammation in the hemi-parkinsonian rat. Neurobiology of aging, 2019, Volume: 81 Topics: Aging; Animals; Dyskinesia, Drug-Induced; Gene Expression; Inflammation; Interleukin-1beta; Interleukin-6; Levodopa; Male; Parkinson Disease; Rats; Rats, Inbred F344; Risk Factors	2019
Dopamine and the cost of aging. Nature neuroscience, 2013, Volume: 16, Issue:5 Topics: Aging; Conditioning, Operant; Dopamine Agents; Female; Humans; Levodopa; Male; Reward	2013
Levodopa, vitamins, ageing and the neuropathy of Parkinson's disease. Journal of neurology, 2013, Volume: 260, Issue:11 Topics: Adult; Aged; Aging; Antiparkinson Agents; Cross-Sectional Studies; Female; Folic Acid; Humans; Levodopa; Male; Middle Aged; Nervous System Diseases; Parkinson Disease; Vitamin B 12	2013
Dopamine as the fountain of youth? Restoring decision making ability in older adults. Neurosurgery, 2013, Volume: 73, Issue:4 Topics: Aging; Conditioning, Operant; Dopamine Agents; Female; Humans; Levodopa; Male; Reward	2013
Age-dependent dopaminergic dysfunction following fetal exposure to atrazine in SD rats. Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Atrazine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Fetus; Herbicides; Homovanillic Acid; Levodopa; Maternal-Fetal Exchange; Nuclear Receptor Subfamily 4, Group A, Member 2; Pregnancy; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins	2014
Age-related decline in the responsiveness of motor cortex to plastic forces reverses with levodopa or cerebellar stimulation. Neurobiology of aging, 2014, Volume: 35, Issue:11 Topics: Adult; Aged; Aging; Cerebellum; Dopamine; Evoked Potentials; Female; Humans; Levodopa; Male; Middle Aged; Motor Cortex; Motor Skills; Neuronal Plasticity; Psychomotor Performance; Synaptic Transmission; Transcranial Direct Current Stimulation; Young Adult	2014
Interrogating the aged striatum: robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integration. Neurobiology of disease, 2015, Volume: 77 Topics: Aging; Amphetamine; Animals; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopaminergic Neurons; Dyskinesia, Drug-Induced; Embryo, Mammalian; Functional Laterality; Levodopa; Neurites; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; Recovery of Function; Stem Cell Transplantation; Substance P	2015
Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients. Aging, 2015, Volume: 7, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Aging; DNA Methylation; Epigenesis, Genetic; Female; Granulocytes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Risk Factors	2015
LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function. Human molecular genetics, 2016, Mar-01, Volume: 25, Issue:5 Topics: Action Potentials; Aging; Amino Acid Substitution; Animals; Antiparkinson Agents; Cell Death; Chromosomes, Artificial, Bacterial; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Female; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Male; Mutation; Parkinson Disease; Promoter Regions, Genetic; Protein Domains; Rats; Rats, Transgenic; Substantia Nigra	2016
Dramatic differences in susceptibility to l-DOPA-induced dyskinesia between mice that are aged before or after a nigrostriatal dopamine lesion. Neurobiology of disease, 2016, Volume: 94 Topics: Aging; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Levodopa; Mice, Inbred C57BL; Motor Activity; Oxidopamine; Parkinson Disease	2016
Octogenarian parkinsonism - Clinicopathological observations. Parkinsonism & related disorders, 2017, Volume: 37 Topics: Aged, 80 and over; Aging; Antiparkinson Agents; Autopsy; Brain; Disease Progression; Female; Humans; Levodopa; Longitudinal Studies; Male; Parkinsonian Disorders	2017
Cerebrospinal fluid levels of catecholamines and its metabolites in Parkinson's disease: effect of l-DOPA treatment and changes in levodopa-induced dyskinesia. Journal of neurochemistry, 2017, Volume: 141, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aging; Antiparkinson Agents; Catecholamines; Dopamine; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Norepinephrine; Parkinson Disease	2017
Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects. Journal of clinical pharmacology, 2009, Volume: 49, Issue:12 Topics: Adult; Aged; Aging; Antiparkinson Agents; Drug Administration Schedule; Female; Humans; Levodopa; Male; Resveratrol; Stilbenes; Young Adult	2009
Melanin precursors prevent premature age-related and noise-induced hearing loss in albino mice. Pigment cell & melanoma research, 2010, Volume: 23, Issue:1 Topics: Aging; Aging, Premature; Albinism; Albinism, Oculocutaneous; Animals; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Hearing Loss, Noise-Induced; Hearing Loss, Sensorineural; Levodopa; Melanins; Mice; Mice, Transgenic; Monophenol Monooxygenase; Tyrosine 3-Monooxygenase	2010
The effect of memantine and levodopa/carbidopa on the responses of phrenic nerve-diaphragm preparations from aged rats. Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:11 Topics: Aging; Animals; Carbidopa; Diaphragm; Electric Stimulation; Gallamine Triethiodide; Gene Expression Regulation; Levodopa; Male; Memantine; Muscle Contraction; Neostigmine; Neuromuscular Blockade; Phrenic Nerve; Protein Subunits; Rats; Receptors, Nicotinic; RNA, Messenger	2009
L-DOPA reverses motor deficits associated with normal aging in mice. Neuroscience letters, 2011, Feb-01, Volume: 489, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Brain Chemistry; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Psychomotor Performance	2011
Influence of ageing on the pharmacokinetics of levodopa in elderly patients with Parkinson's disease. Parkinsonism & related disorders, 2011, Volume: 17, Issue:3 Topics: Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Female; Humans; Levodopa; Male; Parkinson Disease; Statistics, Nonparametric; Time Factors	2011
Proteins containing oxidized amino acids induce apoptosis in human monocytes. The Biochemical journal, 2011, Apr-01, Volume: 435, Issue:1 Topics: Aging; Annexin A5; Apoptosis; Caspase 3; Cell Line; Ceroid; DNA Fragmentation; Enzyme Activation; Humans; Intracellular Membranes; Levodopa; Lipofuscin; Lysosomes; Membrane Potential, Mitochondrial; Mitochondrial Membranes; Monocytes; Oxidation-Reduction; Permeability; Protein Biosynthesis; Tyrosine	2011
A longitudinal study of motor performance and striatal [18F]fluorodopa uptake in Parkinson's disease. Brain imaging and behavior, 2011, Volume: 5, Issue:3 Topics: Aged; Aging; Antiparkinson Agents; Carbidopa; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Female; Hand Strength; Humans; Isometric Contraction; Levodopa; Longitudinal Studies; Male; Middle Aged; Muscle Strength; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Psychomotor Performance; Radiopharmaceuticals; Reaction Time; Retrospective Studies; Sex Characteristics; Tongue	2011
Dichotomy of tyrosine hydroxylase and dopamine regulation between somatodendritic and terminal field areas of nigrostriatal and mesoaccumbens pathways. PloS one, 2012, Volume: 7, Issue:1 Topics: Aging; Animals; Dendrites; Dopamine; Hydrazines; Levodopa; Male; Neostriatum; Neural Pathways; Nucleus Accumbens; Phosphorylation; Phosphoserine; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase; Ventral Tegmental Area	2012
Histamine- and haloperidol-induced catalepsy in aged mice: differential responsiveness to L-DOPA. Psychopharmacology, 2012, Volume: 223, Issue:2 Topics: Aging; Animals; Antiparkinson Agents; Catalepsy; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Histamine; Injections, Intraventricular; Levodopa; Male; Mice; Mice, Inbred BALB C; Parkinson Disease; Time Factors	2012
Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans. Journal of neuroscience research, 2012, Volume: 90, Issue:10 Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Aging; Animals; Antiparkinson Agents; Blotting, Western; Cell Count; Dopamine; Dopaminergic Neurons; Female; G(M1) Ganglioside; Gangliosides; Humans; Immunohistochemistry; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Acetylgalactosaminyltransferases; Parkinson Disease; Polypeptide N-acetylgalactosaminyltransferase; Synucleins; Tyrosine 3-Monooxygenase	2012
Effects of aging and levodopa on the laryngeal adductor reflex in rats. Experimental gerontology, 2012, Volume: 47, Issue:12 Topics: Aging; Animals; Dopamine Agents; Dopaminergic Neurons; Laryngeal Muscles; Laryngeal Nerves; Levodopa; Male; Rats; Rats, Inbred F344; Reaction Time; Reflex	2012
Electrophysiological features of lower motor neuron involvement in progressive supranuclear palsy. Journal of the neurological sciences, 2013, Jan-15, Volume: 324, Issue:1-2 Topics: Action Potentials; Aged; Aging; Antiparkinson Agents; Electrodiagnosis; Electromyography; Female; Humans; Levodopa; Male; Middle Aged; Motor Neuron Disease; Motor Neurons; Muscle, Skeletal; Neural Conduction; Peripheral Nerves; Supranuclear Palsy, Progressive	2013
Age-related changes in the striatal dopaminergic system in the living brain: a multiparametric PET study in conscious monkeys. Synapse (New York, N.Y.), 2002, Volume: 45, Issue:1 Topics: Aging; Animals; Benzazepines; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extracellular Space; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Microdialysis; Piperazines; Raclopride; Tomography, Emission-Computed	2002
Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Nov-15, Volume: 22, Issue:22 Topics: Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Body Weight; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Immunohistochemistry; Levodopa; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Opioid, mu; Signal Transduction; Sodium Chloride	2002
Behavioral responses are altered in piglets with decreased frontal cortex docosahexaenoic acid. The Journal of nutrition, 2003, Volume: 133, Issue:10 Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Brain; Diet; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Dopamine; Dopamine D2 Receptor Antagonists; Energy Intake; Fatty Acids; Fatty Acids, Unsaturated; Frontal Lobe; Levodopa; Male; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Sulpiride; Swine; Weight Gain	2003
Antiparkinsonian medication is not a risk factor for the development of hallucinations in Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996), 2004, Volume: 111, Issue:10-11 Topics: Adult; Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Dementia; Female; Hallucinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Retrospective Studies; Risk Factors; United Kingdom	2004
Dopamine depletion alters phosphorylation of striatal proteins in a model of Parkinsonism. The European journal of neuroscience, 2005, Volume: 22, Issue:1 Topics: Aging; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Levodopa; Male; Nerve Tissue Proteins; Neural Pathways; Neuronal Plasticity; Parkinsonian Disorders; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Presynaptic Terminals; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Substantia Nigra; Synaptic Membranes; Up-Regulation	2005
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease. Neurology, 2005, Nov-08, Volume: 65, Issue:9 Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12	2005
Ontogeny of L-DOPA-induced locomotion: Expression of c-Fos in the brainstem and basal ganglia of rats. Brain research, 2006, Jan-12, Volume: 1068, Issue:1 Topics: Aging; Animals; Arousal; Basal Ganglia; Brain Stem; Data Interpretation, Statistical; Dopamine Agents; Genes, fos; Immunohistochemistry; Levodopa; Locomotion; Male; Prosencephalon; Rats; Rats, Sprague-Dawley	2006
Single-dose levodopa administration and aging independently disrupt time production. Journal of cognitive neuroscience, 2006, Volume: 18, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Aging; Choice Behavior; Dopamine; Female; Humans; Levodopa; Male; Placebos; Reaction Time; Time Perception	2006
Age-related decline of dopamine synthesis in the living human brain measured by positron emission tomography with L-[beta-11C]DOPA. Life sciences, 2006, Jul-17, Volume: 79, Issue:8 Topics: Adult; Aged; Aging; Brain; Dopamine; Humans; Levodopa; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography	2006
Loss of spastic paraplegia gene atlastin induces age-dependent death of dopaminergic neurons in Drosophila. Neurobiology of aging, 2008, Volume: 29, Issue:1 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Animals, Genetically Modified; Cell Death; Cell Proliferation; Dopamine; Dopamine Agonists; Drosophila; Drosophila Proteins; Embryo, Nonmammalian; Gene Expression Regulation; Green Fluorescent Proteins; GTP Phosphohydrolases; GTP-Binding Proteins; Levodopa; Male; Membrane Proteins; Neurons; Sequence Alignment; Tyrosine 3-Monooxygenase	2008
Age-related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease. The European journal of neuroscience, 2006, Volume: 24, Issue:9 Topics: Aging; Animals; Antiparkinson Agents; Blotting, Western; Corpus Striatum; Disease Models, Animal; Dopamine; Immunohistochemistry; Levodopa; Male; Mice; Mice, Mutant Strains; Motor Activity; Motor Skills; Nerve Degeneration; Parkinson Disease; Phosphorylation; Substantia Nigra; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins	2006
Aging of the rat mesostriatal system: differences between the nigrostriatal and the mesolimbic compartments. Experimental neurology, 2007, Volume: 204, Issue:1 Topics: Aging; alpha-Synuclein; Amyloid beta-Protein Precursor; Animals; Axons; Corpus Striatum; Dopa Decarboxylase; Dopamine; Levodopa; Limbic System; Male; Nerve Degeneration; Phosphorylation; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase	2007
Motor fluctuations and dyskinesias in advanced/end stage Parkinson's disease: a study from a population of brain donors. Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:3 Topics: Age of Onset; Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Brain; Cohort Studies; Disease Progression; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Nerve Degeneration; Neuronal Plasticity; Parkinson Disease; Synaptic Transmission; Tissue Donors	2007
High-salt intake and the renal expression of amino acid transporters in spontaneously hypertensive rats. American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:5 Topics: Aging; Amino Acid Transport System ASC; Amino Acid Transport System y+; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Dopamine; Dose-Response Relationship, Drug; Fusion Regulatory Protein 1, Light Chains; Hypertension; Kidney; Kidney Tubules; Large Neutral Amino Acid-Transporter 1; Levodopa; Minor Histocompatibility Antigens; Neurotransmitter Agents; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Sodium Chloride, Dietary	2007
Relationship between age and subtypes of psychotic symptoms in Parkinson's disease. Journal of neurology, 2007, Volume: 254, Issue:4 Topics: Age of Onset; Aged; Aging; Antiparkinson Agents; Delusions; Female; Hallucinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Statistics, Nonparametric	2007
[Segawa disease]. Brain and nerve = Shinkei kenkyu no shinpo, 2008, Volume: 60, Issue:1 Topics: Aging; Brain; Dopamine; Dystonia; Female; GTP Cyclohydrolase; History, 20th Century; Humans; Levodopa; Phenotype; Pteridines	2008
[Precoce survey: a new self-assessment patient card for early detection and management of Parkinson disease fluctuations]. Revue neurologique, 2008, Volume: 164, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Reproducibility of Results; Surveys and Questionnaires	2008
Enkephalin receptor changes in rat brain during aging. General pharmacology, 1984, Volume: 15, Issue:6 Topics: Aging; Animals; Cerebral Cortex; Corpus Striatum; Haloperidol; Hypothalamus; Levodopa; Male; Rats; Rats, Inbred Strains; Receptors, Opioid	1984
Progressive supranuclear palsy: clinico-pathological and biochemical studies. Journal of neural transmission. Supplementum, 1980, Issue:16 Topics: Adolescent; Adult; Aged; Aging; Brain; Brain Chemistry; Bulbar Palsy, Progressive; Female; Humans; Levodopa; Male; Middle Aged; Tyrosine 3-Monooxygenase	1980
Reinstatement of LH surges by serotonin neuroleptics in aging, constant estrous rats. Neurobiology of aging, 1982,Fall, Volume: 3, Issue:3 Topics: 5-Hydroxytryptophan; Aging; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Castration; Estradiol; Estrus; Female; Fenclonine; Levodopa; Luteinizing Hormone; Methyltyrosines; Muridae; Pargyline; Pregnancy; Progesterone; Serotonin	1982
Neuroendocrinological signs of central neurotransmission disorders. Cephalalgia : an international journal of headache, 1983, Volume: 3 Suppl 1 Topics: Aging; Central Nervous System Diseases; Endocrine System Diseases; Headache; Humans; Levodopa; Neurotransmitter Agents; Nociceptors; Nomifensine; Periodicity; Prolactin	1983
Age-dependent depressor effect of L-dopa in dogs with inhibition of extracerebral dopa decarboxylase. Pediatric research, 1983, Volume: 17, Issue:11 Topics: Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain; Carbidopa; Dogs; Drug Therapy, Combination; Heart Rate; Levodopa; Male; Renin; Renin-Angiotensin System; Time Factors	1983
[Adrenergic mechanisms regulating the motor reactions of rats in the early postnatal period]. Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:9 Topics: Aging; Animals; Animals, Newborn; Chlorpromazine; Levodopa; Motor Activity; Rats; Receptors, Adrenergic; Reserpine	1984
Variability in Parkinson's disease; clinical aspects, causes and treatment. Acta neurologica Scandinavica. Supplementum, 1983, Volume: 95 Topics: Aging; Fatigue; Humans; Levodopa; Movement Disorders; Neurasthenia; Parkinson Disease; Sleep	1983
The development of catecholaminergic nerves in the spinal cord of rat. II. Regional development. Brain research, 1983, Volume: 313, Issue:1 Topics: Aging; Animals; Dopamine; Female; Fetus; Levodopa; Microscopy, Fluorescence; Norepinephrine; Pregnancy; Rats; Spinal Cord	1983
Synthesis of catecholamines in the developing spinal cord of the rat. Journal of neurochemistry, 1984, Volume: 42, Issue:6 Topics: Aging; Animals; Dopamine; Kinetics; Levodopa; Nialamide; Norepinephrine; Rats; Rats, Inbred Strains; Spinal Cord	1984
Studies on fluorescent granular perithelium (F.G.P.) of rat cerebral cortex - especially referring to morphological changes in aging. Anatomischer Anzeiger, 1981, Volume: 149, Issue:5 Topics: 5-Hydroxytryptophan; Aging; Animals; Animals, Newborn; Blood Vessels; Cerebral Cortex; Dioxoles; Levodopa; Microscopy, Fluorescence; Rats; Serotonin	1981
Age-dependent reduction in maximum electroshock convulsive threshold associated with decreased concentrations of brain monoamines. Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:3 Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Aging; Animals; Biogenic Amines; Brain Chemistry; Electroshock; Female; Hydroxydopamines; Levodopa; p-Chloroamphetamine; Pregnancy; Rats; Rats, Inbred Strains; Seizures; Tetrabenazine	1982
Effects of centrally and systemically administered L-tyrosine and L-leucine on ovarian function in the old rat. Gerontology, 1980, Volume: 26, Issue:5 Topics: Aging; Animals; Catecholamines; Estrus; Female; Leucine; Levodopa; Ovary; Pregnancy; Preoptic Area; Rats; Serotonin; Tyrosine	1980
Maintenance by L-DOPA treatment of estrous cycles and LH response to estrogen in aging female rats. Experimental aging research, 1980, Volume: 6, Issue:6 Topics: Aging; Animals; Castration; Estradiol; Estrus; Female; Hypothalamo-Hypophyseal System; Levodopa; Luteinizing Hormone; Pituitary-Adrenal System; Pregnancy; Prolactin; Rats	1980
Secretion of hypothalamic dopamine into pituitary stalk blood of aged female rats. Brain research bulletin, 1981, Volume: 7, Issue:1 Topics: Aging; Animals; Dopamine; Estrus; Female; Hypothalamus; Levodopa; Median Eminence; Pituitary Gland; Pregnancy; Prolactin; Rats; Tyrosine	1981
Age-related motor and catecholamine alterations in mice on levodopa supplemented diet. Life sciences, 1981, Jun-29, Volume: 28, Issue:26 Topics: Aging; Animals; Brain Chemistry; Catecholamines; Diet; Levodopa; Male; Mice; Motor Activity; Quinuclidinyl Benzilate; Receptors, Dopamine; Receptors, Muscarinic; Spiperone	1981
Hypothermic effect of dopamine and L-DOPA in the domestic fowl (Gallus domesticus). General pharmacology, 1981, Volume: 12, Issue:5 Topics: Aging; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Body Temperature; Chickens; Depression, Chemical; Dopamine; Drug Interactions; Levodopa; Male	1981
Age related changes in the control of prolactin secretion in the female rat. Neurobiology of aging, 1981,Summer, Volume: 2, Issue:2 Topics: Aging; Animals; Castration; Dopamine; Estrogens; Female; Hypothalamus; Levodopa; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine	1981
A case of sporadic juvenile Parkinson's disease. Archives of neurology, 1981, Volume: 38, Issue:11 Topics: Adult; Aging; Carbidopa; Female; Humans; Levodopa; Parkinson Disease	1981
Influence of exogenous L-3,4,-dihydroxyphenylalanine (L-dopa) on the methionine and s-adenosylmethionine concentrations in the brain and other tissues [proceedings]. Biochemical Society transactions, 1980, Volume: 8, Issue:1 Topics: Aging; Animals; Brain; Iproniazid; Kidney; Levodopa; Liver; Methionine; Organ Specificity; Rats; S-Adenosylmethionine	1980
Effects of neonatal and adult 6-hydroxydopamine treatment on random-interval behavior. Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:2 Topics: Aging; Animals; Animals, Newborn; Apomorphine; Brain Chemistry; Catecholamines; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Hydroxydopamines; Levodopa; Male; Mice; Rats; Reinforcement Schedule; Time Factors	1980
Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice. Gerontology, 1980, Volume: 26, Issue:5 Topics: Adenocarcinoma; Aging; Animals; Female; Leukemia, Experimental; Levodopa; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Phenformin; Phenytoin	1980
Age-related changes on monoamine turnover in hippocampus of rats. Brain research, 1993, Dec-17, Volume: 631, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Hippocampus; Hydroxyindoleacetic Acid; Immunohistochemistry; Levodopa; Male; Monoamine Oxidase; Norepinephrine; Rats; Rats, Wistar; Serotonin	1993
Effect of ageing on monoamine turnover in the prefrontal cortex of rats. Mechanisms of ageing and development, 1993, Dec-15, Volume: 72, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pargyline; Prefrontal Cortex; Probenecid; Rats; Rats, Wistar; Serotonin; Tyrosine 3-Monooxygenase	1993
Ontogeny of the cell outward dopamine transporter in canine renal tissues. Fundamental & clinical pharmacology, 1995, Volume: 9, Issue:3 Topics: Aging; Animals; Animals, Newborn; Aromatic-L-Amino-Acid Decarboxylases; Carrier Proteins; Dogs; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Kidney; Kinetics; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins	1995
L-dopa-induced air-stepping in preweanling rats. I. Effects of dose and age. Brain research. Developmental brain research, 1994, Oct-14, Volume: 82, Issue:1-2 Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Gait; Levodopa; Male; Motor Activity; Rats; Stereotyped Behavior	1994
L-dopa-induced air-stepping in preweanling rats. II. Kinematic analyses. Brain research. Developmental brain research, 1994, Oct-14, Volume: 82, Issue:1-2 Topics: Aging; Animals; Female; Forelimb; Gait; Hindlimb; Levodopa; Male; Motor Activity; Rats; Stereotyped Behavior; Time Factors; Videotape Recording	1994
Immunocytochemical localization of L-dopa and dopamine in the brain of the chicken (Gallus domesticus). The Journal of comparative neurology, 1994, Aug-01, Volume: 346, Issue:1 Topics: Aging; Animals; Brain Chemistry; Chickens; Dopamine; Female; Immunohistochemistry; Levodopa; Nerve Endings	1994
Neurochemical characterization of the alterations in the noradrenergic afferents to the cerebellum of adult rats exposed to X-irradiation at birth. Journal of neurochemistry, 1993, Volume: 61, Issue:2 Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Afferent Pathways; Aging; Animals; Animals, Newborn; Cerebellar Cortex; Cerebellum; Female; In Vitro Techniques; Kinetics; Levodopa; Male; Norepinephrine; Rats; Rats, Wistar; Reserpine; Tritium; Tyrosine 3-Monooxygenase	1993
Hypothesis: the bradyphrenia of parkinsonism is a nosological entity. Acta neurologica Scandinavica, 1993, Volume: 87, Issue:4 Topics: Adult; Aged; Aging; Alcohol Drinking; Antiparkinson Agents; Cognition; Cognition Disorders; Depressive Disorder; Ethanol; Female; Humans; Levodopa; Male; Middle Aged; Motor Skills; Parkinson Disease; Probability; Psychological Tests; Reaction Time	1993
Ontogenetic development of the locomotor response to levodopa in the rat. Pediatric neurology, 1996, Volume: 14, Issue:1 Topics: Aging; Animals; Animals, Newborn; Autoreceptors; Brain; Female; Injections, Intraperitoneal; Levodopa; Locomotion; Male; Motor Activity; Norepinephrine; Rats; Receptors, Dopamine	1996
Age-related decrease in responsiveness to L-DOPA is not due to changes in dopamine receptor mRNAs or G protein mRNAs. Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:3 Topics: Actins; Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Blotting, Northern; Brain Chemistry; Female; GTP-Binding Proteins; Humans; In Vitro Techniques; Levodopa; Male; Middle Aged; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger	1996
[Brain catecholamines and the hypothalamo-hypophyseal-adrenocortical system in hereditary arterial hypertension]. Fiziologicheskii zhurnal imeni I.M. Sechenova, 1996, Volume: 82, Issue:4 Topics: Aging; Animals; Blood Pressure; Brain; Brain Chemistry; Carbidopa; Catecholamines; Dopamine Agonists; Drug Combinations; Female; Hypertension; Hypothalamo-Hypophyseal System; Levodopa; Male; Pituitary-Adrenal System; Rats; Rats, Inbred SHR; Rats, Wistar; Stress, Psychological	1996
The pattern electroretinogram in Parkinson's disease reveals lack of retinal spatial tuning. Electroencephalography and clinical neurophysiology, 1996, Volume: 100, Issue:1 Topics: Aged; Aged, 80 and over; Aging; Disease Progression; Electroretinography; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Reference Values; Retina; Space Perception; Time Perception; Visual Perception	1996
A kinematic comparison of L-DOPA-induced air-stepping and swimming in developing rats. Developmental psychobiology, 1997, Volume: 30, Issue:4 Topics: Aging; Animals; Animals, Newborn; Dopamine Agents; Female; Levodopa; Locomotion; Male; Motor Activity; Motor Skills; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Swimming	1997
Unilateral pallidotomy for Parkinson's disease: comparison of outcome in younger versus elderly patients. Neurology, 1997, Volume: 49, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Globus Pallidus; Humans; Levodopa; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Postoperative Complications; Severity of Illness Index; Treatment Outcome	1997
Parkinson's disease: clinical features. Bailliere's clinical neurology, 1997, Volume: 6, Issue:1 Topics: Aging; Antiparkinson Agents; Diagnosis, Differential; Humans; Levodopa; Neurologic Examination; Parkinson Disease; Parkinson Disease, Secondary; Treatment Outcome	1997
The developing prefrontal cortex: is there a transient interneuron that stimulates catecholamine terminals? Synapse (New York, N.Y.), 1998, Volume: 29, Issue:1 Topics: Aging; Animals; Catecholamines; Interneurons; Levodopa; Nerve Endings; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Tissue Distribution	1998
Dopamine-dependent inhibition of jejunal Na+-K+-ATPase during high-salt diet in young but not in adult rats. The American journal of physiology, 1998, Volume: 275, Issue:6 Topics: Absorption; Adenosine Triphosphate; Aging; Animals; Diet, Sodium-Restricted; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Hydrolysis; Intestinal Mucosa; Jejunum; Levodopa; Norepinephrine; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Sodium; Sodium-Potassium-Exchanging ATPase	1998
Objective assessment in Parkinson's disease: optoelectronic movement and force analysis in clinical routine and research. Advances in neurology, 1999, Volume: 80 Topics: Aging; Antiparkinson Agents; Dopamine Agonists; Electronics; Hand; Hand Strength; Humans; Levodopa; Methods; Movement; Optics and Photonics; Parkinson Disease; Posture; Reference Values; Tremor	1999
Aging, high salt intake, and renal dopaminergic activity in Fischer 344 rats. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:4 Pt 1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Aromatic-L-Amino-Acid Decarboxylases; Catecholamines; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Kidney; Levodopa; Male; Monoamine Oxidase; Rats; Rats, Inbred F344; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase	1999
Evaluation of L-DOPA biotransformation during repeated L-DOPA infusion into the striatum in freely-moving young and old rats. Brain research. Developmental brain research, 2000, May-11, Volume: 121, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antiparkinson Agents; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Locomotion; Male; Microdialysis; Rats; Rats, Wistar	2000
Changes in endogenous monoamines in aged rats. Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Catechol O-Methyltransferase; Cerebral Cortex; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Monoamine Oxidase; Norepinephrine; Rats; Rats, Wistar; Serotonin	2001
Efficacy and tolerability of dopamine agonists in a parkinsonian population. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2001, Volume: 22, Issue:1 Topics: Age of Onset; Aged; Aging; Benzothiazoles; Bromocriptine; Dopamine Agonists; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Ergolines; Female; Follow-Up Studies; Humans; Indoles; Levodopa; Lisuride; Male; Middle Aged; Parkinson Disease; Pergolide; Pramipexole; Retrospective Studies; Thiazoles; Treatment Outcome	2001
Heart failure, aging, and renal synthesis of dopamine. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Age Factors; Aged; Aging; Aldosterone; Cardiac Output, Low; Case-Control Studies; Creatinine; Diet, Sodium-Restricted; Dopamine; Echocardiography; Female; Homovanillic Acid; Humans; Kidney; Levodopa; Male; Middle Aged; Norepinephrine; Statistics as Topic; Urine	2001
Salt intake and intestinal dopaminergic activity in adult and old Fischer 344 rats. Life sciences, 2001, Sep-14, Volume: 69, Issue:17 Topics: Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dopamine; Jejunum; Levodopa; Male; Rats; Rats, Inbred F344; Sodium Chloride; Sodium-Potassium-Exchanging ATPase	2001
Speech motor stability in IPD: effects of rate and loudness manipulations. Journal of speech, language, and hearing research : JSLHR, 2001, Volume: 44, Issue:5 Topics: Aged; Aging; Antiparkinson Agents; Dysarthria; Female; Humans; Levodopa; Lip; Loudness Perception; Male; Mandible; Middle Aged; Parkinson Disease; Severity of Illness Index; Speech	2001
Effect of tetrabenazine on the striatal uptake of exogenous L-DOPA in vivo: a PET study in young and aged rhesus monkeys. Synapse (New York, N.Y.), 2002, Jun-15, Volume: 44, Issue:4 Topics: Adrenergic Uptake Inhibitors; Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; Dopamine Agents; Image Processing, Computer-Assisted; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Neuropeptides; Tetrabenazine; Tomography, Emission-Computed; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins	2002
The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease. Journal of neurochemistry, 2002, Volume: 81, Issue:1 Topics: Aging; Animals; Behavior, Animal; Brain; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Huntington Disease; Levodopa; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Spatial Behavior; Survival Rate	2002
Determination of some L-3,4-dihydroxyphenylalanine and dopamine metabolites in urine by means of mass fragmentography. Clinical chemistry, 1978, Volume: 24, Issue:1 Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Adult; Aging; Child; Child, Preschool; Dihydroxyphenylalanine; Dopamine; Flavoring Agents; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Infant; Infant, Newborn; Lactates; Levodopa; Middle Aged; Neuroblastoma; Phenylethyl Alcohol	1978
Effects of aging and chronic sun exposure on melanocytes in human skin. The Journal of investigative dermatology, 1979, Volume: 73, Issue:2 Topics: Adult; Aged; Aging; Cell Count; Humans; Levodopa; Male; Melanocytes; Middle Aged; Skin; Staining and Labeling; Sunlight	1979
Chemically evoked hypothermia in the mouse: towards a method for investigating thermodynamic parameters of aging and death in mammals. Mechanisms of ageing and development, 1978, Volume: 7, Issue:5 Topics: Adaptation, Physiological; Aging; Animals; Chlorpromazine; Drug Synergism; Female; Fenclonine; Hypothermia; Levodopa; Male; Methods; Mice; Mice, Inbred ICR; Reserpine; Sex Factors; Thermodynamics	1978
[Increase in longevity and a decrease in the frequency of tumors in C3H/Sn mice under the influence of fenformin and diphenin]. Doklady Akademii nauk SSSR, 1979, Volume: 245, Issue:3 Topics: Aging; Animals; Female; Levodopa; Longevity; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Phenformin; Phenytoin; Time Factors	1979
Movement disorders of aged rats: reversal by dopamine receptor stimulation. Science (New York, N.Y.), 1979, Oct-26, Volume: 206, Issue:4417 Topics: Aging; Animals; Apomorphine; Levodopa; Male; Movement Disorders; Rats; Receptors, Dopamine; Swimming; Time Factors	1979
Effect of L-dopa on the ovary of aged hens. Poultry science, 1979, Volume: 58, Issue:6 Topics: Aging; Animals; Body Weight; Chickens; Feathers; Female; Injections, Subcutaneous; Levodopa; Ovary; Oviducts; Ovulation	1979
Reinstatement of ovarian cycles in aged female rats by placement of L-dopa in the medial preoptic area [proceedings]. Advances in experimental medicine and biology, 1978, Volume: 97 Topics: Aging; Animals; Female; Levodopa; Ovary; Periodicity; Preoptic Area; Rats	1978
Pharmacological induction of ovulation in old and neonatally androgenized rats. Experimental gerontology, 1978, Volume: 13, Issue:3-4 Topics: Aging; Animals; Animals, Newborn; Brain; Female; Iproniazid; Levodopa; Ovulation; Ovulation Induction; Progesterone; Rats; Receptors, Steroid; Testosterone	1978
[Age and changes in the levels of biogenic amines in the brains of rats]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1977, Volume: 63, Issue:3 Topics: Age Factors; Aging; Animals; Biogenic Amines; Brain Chemistry; Brain Stem; Dopamine; Histamine; Hydroxyindoleacetic Acid; Levodopa; Male; Norepinephrine; Rats; Serotonin; Sexual Maturation	1977
Reinstatement of vaginal cycles in aged female rats. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 199, Issue:2 Topics: Aging; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drug Interactions; Estrus; Female; Fusaric Acid; Hypophysectomy; Levodopa; Phenoxybenzamine; Pimozide; Pregnancy; Propranolol; Rats; Tyrosine; Vagina	1976
Aging and the passage of L-tyrosine, L-DOPA, and inulin into mouse brain slices in vitro. Journal of gerontology, 1975, Volume: 30, Issue:1 Topics: Aging; Animals; Biological Transport, Active; Brain; Brain Stem; Corpus Striatum; Hypothalamus; In Vitro Techniques; Inulin; Levodopa; Male; Mice; Mice, Inbred C57BL; Tritium; Tyrosine	1975
Effects of aging on LH and prolactin after LHRL L-dopa, methyl-dopa, and stress in male rat. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 151, Issue:3 Topics: Aging; Animals; Hypothalamus; Levodopa; Luteinizing Hormone; Male; Methyldopa; Pituitary Gland, Anterior; Prolactin; Rats; Stress, Physiological	1976
Effect of alpha-human atrial natriuretic peptide on the synthesis of dopamine in the rat kidney. British journal of pharmacology, 1992, Volume: 105, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Aging; Animals; Atrial Natriuretic Factor; Dopamine; In Vitro Techniques; Kidney; Levodopa; Male; Purinones; Rats; Rats, Inbred Strains; Sodium, Dietary	1992
Postural inflexibility in parkinsonian subjects. Journal of the neurological sciences, 1992, Volume: 111, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Aging; Electromyography; Female; Humans; Levodopa; Male; Middle Aged; Muscles; Parkinson Disease; Postural Balance; Posture; Reflex	1992
Muscle stiffness and continuous electromyographic activity in old rats; an animal model for spasticity? Neuroscience, 1992, Volume: 51, Issue:1 Topics: Aging; Animals; Atrophy; Baclofen; Benserazide; Drug Combinations; Electromyography; Female; Levodopa; Muscle Contraction; Muscle Denervation; Muscle Spasticity; Muscle Tonus; Muscles; Rats; Rats, Wistar	1992
Use of [3H]-GBR12935 to measure dopaminergic nerve terminal growth into the developing rat striatum. Brain research. Developmental brain research, 1992, Jun-19, Volume: 67, Issue:2 Topics: Aging; Animals; Biological Transport; Corpus Striatum; Dopamine; Embryonic and Fetal Development; Gestational Age; Levodopa; Male; Nerve Endings; Piperazines; Rats; Rats, Inbred Strains; Tritium	1992
Cardiac beta-adrenoceptor sensitivity and Parkinson's disease. Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:6 Topics: Aged; Aging; Blood Pressure; Bromocriptine; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Isoproterenol; Levodopa; Male; Middle Aged; Myocardium; Parkinson Disease; Piribedil; Receptors, Adrenergic, beta	1991
Dopamine D2 receptor imaging with SPECT: studies in different neuropsychiatric disorders. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1991, Volume: 11, Issue:2 Topics: Adult; Aged; Aging; Antipsychotic Agents; Benzamides; Brain Diseases; Cerebellum; Corpus Striatum; Frontal Lobe; Humans; Huntington Disease; Iodine Radioisotopes; Levodopa; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Tissue Distribution; Tomography, Emission-Computed, Single-Photon	1991
Age effects on monoamine turnover of the rat substantia nigra. Brain research, 1991, Aug-23, Volume: 557, Issue:1-2 Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydrazines; In Vitro Techniques; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra	1991
Striatal dopamine release in vitro from immature male rats shows enhanced responsiveness to pulsatile, but not continuous, infusions of L-dopa. Brain research. Developmental brain research, 1991, Oct-21, Volume: 62, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Levodopa; Male; Pulsatile Flow; Rats; Rats, Inbred Strains	1991
A study on the renal synthesis of dopamine in aged rats. Acta physiologica Scandinavica, 1991, Volume: 143, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Chromatography, High Pressure Liquid; Dopamine; Kidney; Levodopa; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine	1991
A new motor test sensitive to aging and dopaminergic function. Journal of neuroscience methods, 1991, Volume: 39, Issue:2 Topics: Aging; Animals; Body Weight; Dextroamphetamine; Dopamine; Haloperidol; Levodopa; Male; Motor Activity; Neuropsychological Tests; Rats; Rats, Inbred Strains	1991
Dopaminergic regulation of gonadotropin and thyrotropin hormone secretion is altered with age. Hormone research, 1991, Volume: 36, Issue:1-2 Topics: Adult; Aged; Aged, 80 and over; Aging; Dopamine; Follicle Stimulating Hormone; Growth Hormone; Humans; Levodopa; Luteinizing Hormone; Male; Middle Aged; Prolactin; Thyrotropin	1991
Dopamine D1 receptor behavioral responsitivity following selective lesions of the striatal patch compartment during development. Brain research. Developmental brain research, 1991, Jun-21, Volume: 60, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Analysis of Variance; Animals; Animals, Newborn; Apomorphine; Autoradiography; Corpus Striatum; Haloperidol; Hydroxydopamines; Levodopa; Mazindol; Motor Activity; Neurotoxins; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior; Tritium	1991
Positron emission tomography suggests that the rate of progression of idiopathic parkinsonism is slow. Annals of neurology, 1991, Volume: 29, Issue:6 Topics: Adult; Aged; Aging; Corpus Striatum; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors; Tomography, Emission-Computed	1991
The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats. Journal of neural transmission. General section, 1991, Volume: 85, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amphetamine; Animals; Corpus Striatum; Dopamine; In Vitro Techniques; Levodopa; Male; Rats; Selegiline	1991
Age-related decrease in plasma growth hormone: response to growth hormone-releasing hormone, arginine, and L-dopa in obesity. Metabolism: clinical and experimental, 1991, Volume: 40, Issue:12 Topics: Adolescent; Adult; Aged; Aging; Arginine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Levodopa; Male; Middle Aged; Obesity	1991
Early development of levodopa-induced dyskinesias and response fluctuations in young-onset Parkinson's disease. Neurology, 1991, Volume: 41, Issue:2 ( Pt 1) Topics: Adult; Aging; Dyskinesia, Drug-Induced; Humans; Levodopa; Middle Aged; Movement; Parkinson Disease; Probability; Severity of Illness Index; Time Factors	1991
Impaired secretion of growth hormone-releasing hormone, growth hormone and IGF-I in elderly men. Acta endocrinologica, 1991, Volume: 124, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Aging; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Insulin-Like Growth Factor I; Levodopa; Male; Radioimmunoassay	1991
L-dopa-induced air-stepping in decerebrate developing rats. Brain research. Developmental brain research, 1991, Feb-22, Volume: 58, Issue:2 Topics: Aging; Animals; Animals, Newborn; Decerebrate State; Denervation; Electromyography; Levodopa; Motor Activity; Rats; Rats, Inbred Strains; Spinal Cord; Thorax	1991
Changes in dopamine release in vitro from the corpus striatum of young versus aged rats as a function of infusion modes of L-dopa, potassium, and amphetamine. Experimental neurology, 1991, Volume: 112, Issue:2 Topics: Aging; Amphetamine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Infusions, Parenteral; Levodopa; Male; Potassium; Rats; Rats, Inbred Strains; Reference Values	1991
[The sympathetic-adrenal system in mitral heart defects in patients of different ages studied by the use of a specific L-DOPA test]. Terapevticheskii arkhiv, 1990, Volume: 62, Issue:11 Topics: Adrenal Glands; Adult; Aged; Aging; Dopamine; Epinephrine; Female; Heart Failure; Humans; Levodopa; Male; Middle Aged; Mitral Valve Insufficiency; Mitral Valve Stenosis; Norepinephrine; Sympathetic Nervous System; Vanilmandelic Acid	1990
Vesicular and ganglionic norepinephrine in the rat: progressive increase with age. Journal of neurochemistry, 1990, Volume: 54, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Catecholamines; Chromatography, High Pressure Liquid; Cytoplasm; Dopamine; Ganglia, Sympathetic; Levodopa; Male; Norepinephrine; Osmolar Concentration; Rats; Rats, Inbred Strains; Synaptic Vesicles	1990
Correction of arterial blood pressure in adult rats with inherited stress-induced arterial hypertension by enhancement of catecholamine metabolism in early postnatal period. Endocrinologia experimentalis, 1990, Volume: 24, Issue:1-2 Topics: Aging; Animals; Animals, Newborn; Blood Pressure; Catecholamines; Hypertension; Levodopa; Male; Rats; Rats, Inbred Strains; Stress, Physiological	1990
The effect of L-dopa upon in vitro dopamine release from the corpus striatum of young and old male rats. Experimental neurology, 1989, Volume: 106, Issue:3 Topics: Aging; Animals; Corpus Striatum; Dopamine; In Vitro Techniques; Levodopa; Male; Naloxone; Rats; Rats, Inbred Strains	1989
Effect of mild postnatal hypoxia and L-dopa administration on dopamine concentration in striata of the newborn rat and long term sequelae on dopamine turnover. Biomedica biochimica acta, 1989, Volume: 48, Issue:2-3 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Hypoxia, Brain; Levodopa; Rats; Rats, Inbred Strains; Reference Values	1989
Skin color, aging, and plasma L-dopa levels. Journal of the autonomic nervous system, 1989, Volume: 26, Issue:3 Topics: Adolescent; Adult; Aged; Aging; Black People; Humans; Levodopa; Middle Aged; Norepinephrine; Skin Pigmentation; White People	1989
Effect of age at onset on progression and mortality in Parkinson's disease. Neurology, 1989, Volume: 39, Issue:9 Topics: Aging; Athetosis; Chorea; Disability Evaluation; Humans; Levodopa; Middle Aged; Parkinson Disease	1989
Recent developments in the treatment of Parkinson's disease. Geriatrics, 1985, Volume: 40, Issue:2 Topics: Aged; Aging; Amantadine; Diagnosis, Differential; Drug Administration Schedule; Dyskinesia, Drug-Induced; Histamine H1 Antagonists; Humans; Levodopa; Parasympatholytics; Parkinson Disease; Physical Exertion	1985
Neurotransmitter precursors and brain function. Bibliotheca nutritio et dieta, 1986, Issue:38 Topics: Aged; Aging; Alzheimer Disease; Animals; Biological Transport; Brain; Diet; Humans; Learning; Levodopa; Memory; Neurotransmitter Agents; Parkinson Disease; Phosphatidylcholines; Serotonin; Sleep; Tryptophan	1986
Effect of age on gastrointestinal and hepatic first-pass effects of levodopa in rats. The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:6 Topics: Administration, Oral; Aging; Animals; Biological Availability; Digestive System; Feces; Injections; Injections, Intravenous; Jejunum; Kinetics; Levodopa; Liver; Liver Circulation; Male; Portal Vein; Rats; Regional Blood Flow	1987
Changes in the 5-HT-binding sites in the cerebral cortex, striatum and hypothalamus of rats during ageing and under the effect of dopaminergic agents. Acta physiologica et pharmacologica Bulgarica, 1987, Volume: 13, Issue:1 Topics: Aging; Animals; Binding Sites; Cerebral Cortex; Corpus Striatum; Haloperidol; Hypothalamus; Levodopa; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin	1987
Response to brief levodopa infusions in parkinsonian patients with and without motor fluctuations. Neurology, 1988, Volume: 38, Issue:5 Topics: Aged; Aging; Humans; Levodopa; Middle Aged; Movement; Parkinson Disease; Time Factors	1988
Neuropharmacological intervention with motor system aging. Annals of the New York Academy of Sciences, 1988, Volume: 515 Topics: Adult; Aged; Aging; Cognition; Gait; Humans; Levodopa; Middle Aged; Movement Disorders; Neuropharmacology; Neuropsychological Tests; Parkinson Disease; Posture; Reaction Time; Sympathomimetics	1988
Human motor behavior and aging. Annals of the New York Academy of Sciences, 1988, Volume: 515 Topics: Aged; Aging; Brain; Extrapyramidal Tracts; Humans; Levodopa; Movement; Parkinson Disease; Reference Values	1988
Pharmacology of mental aging and dementia disorders. Clinical neuropharmacology, 1987, Volume: 10, Issue:4 Topics: Acetylcholine; Aging; Alzheimer Disease; Dementia; Humans; Levodopa; Neuropeptides	1987
[Critical review of geriatric preparations]. Revista clinica espanola, 1987, Volume: 180, Issue:1 Topics: Aging; Androsterone; Free Radicals; Humans; Levodopa; Life Expectancy	1987
Transient shortening of estrous cycles in aging C57BL/6J mice: effects of spontaneous pseudopregnancy, progesterone, L-dihydroxyphenylalanine, and hydergine. Biology of reproduction, 1987, Volume: 36, Issue:4 Topics: Aging; Animals; Carbidopa; Dihydroergotoxine; Estrus; Female; Levodopa; Mice; Mice, Inbred C57BL; Ovulation; Progesterone; Pseudopregnancy; Silicone Elastomers; Time Factors	1987
Age dependence in capacity-limited jejunal decarboxylation of levodopa in rats. Biochemical pharmacology, 1987, Jul-01, Volume: 36, Issue:13 Topics: Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dopa Decarboxylase; Jejunum; Kinetics; Levodopa; Male; Mesenteric Veins; Rats; Rats, Inbred Strains	1987
[Correction of arterial pressure in rats with hereditary hypertension by altering catecholamine metabolism in early ontogeny]. Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 104, Issue:10 Topics: Aging; Animals; Blood Pressure; Catecholamines; Dopamine beta-Hydroxylase; Hypertension; Levodopa; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains	1987
[Regulation of isoproterenol-induced salivary gland hyperplasia in young and old mice by substances affecting the serotonin- and dopaminergic systems]. Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:4 Topics: Aging; Animals; Female; Freund's Adjuvant; Hyperplasia; Isoproterenol; Levodopa; Mice; Mice, Inbred BALB C; Receptors, Dopamine; Receptors, Serotonin; Salivary Glands; Serotonin; Time Factors	1986
Treatment with levodopa of motor dysfunction in the elderly. Neurology, 1986, Volume: 36, Issue:3 Topics: Aged; Aging; Humans; Levodopa; Motor Neurons; Neuromuscular Diseases; Receptors, Dopamine	1986
Growth hormone restores protein synthesis in skeletal muscle of old male rats. Journal of gerontology, 1985, Volume: 40, Issue:6 Topics: Age Factors; Aging; Animals; Diaphragm; Growth Hormone; Levodopa; Male; Muscle Proteins; Muscles; Phenylalanine; Rats; Rats, Inbred Strains	1985