levodopa has been researched along with Aging in 181 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 59 (32.60) | 18.7374 |
1990's | 54 (29.83) | 18.2507 |
2000's | 33 (18.23) | 29.6817 |
2010's | 32 (17.68) | 24.3611 |
2020's | 3 (1.66) | 2.80 |
Authors | Studies |
---|---|
Kleppe, R; Ruoff, P; Waheed, Q | 1 |
Bhidayasiri, R; Phokaewvarangkul, O; Virameteekul, S | 1 |
D'Amelio, M; Giacalone, E; Keller, F; Krashia, P; La Barbera, L; Lupascu, CA; Migliore, M; Nobili, A; Renzi, M; Spoleti, E | 1 |
Hanajima, R; Ohminami, S; Shimizu, T; Shirota, Y; Tanaka, N; Terao, Y; Tsuji, S; Tsutsumi, R; Ugawa, Y | 1 |
Bugdol, M; Czernek, M; Derejczyk, J; Kapko, W; Kawa, J; Marcisz, C; Seiffert, P; Stępień-Wyrobiec, O; Szymszal, J; Torbus, A | 1 |
Donsante, C; Fan, X; Harrast, P; Hess, EJ; Jinnah, HA; Joers, V; Rose, SJ; Tansey, MG | 1 |
MacDonald, PA; Seergobin, KN; Vo, A | 1 |
Ahn, JH; Cho, JW; Cho, KR; Kim, M; Lee, JI; Park, JH; Park, S; Youn, J | 1 |
Albrecht, F; Ballarini, T; Bezdicek, O; Jech, R; Mueller, K; Roth, J; Růžička, E; Růžička, F; Schroeter, ML; Vymazal, J | 1 |
Bishop, C; Deak, T; Lanza, K; Perkins, AE | 1 |
Chowdhury, R; Dayan, P; Dolan, RJ; Düzel, E; Guitart-Masip, M; Huys, Q; Lambert, C | 1 |
Shohamy, D; Wimmer, GE | 1 |
Müller, T | 1 |
Martey, J; Rajabally, YA | 1 |
Anderson, W; Badugu, S | 1 |
Li, B; Li, Y; Sun, Y; Wu, Y; Yang, J; Yu, J | 1 |
Backer, F; Govind, P; James, P; Kishore, A; Meunier, S; Popa, T; Pradeep, S; Varughese Chacko, L; Yahia-Cherif, L | 1 |
Collier, TJ; Gebremedhin, KG; O'Malley, J; Paumier, KL; Rademacher, DJ; Sisson, KA; Sortwell, CE; Stancati, JA; Steece-Collier, K | 1 |
Horvath, S; Ritz, BR | 1 |
Alegre-Abarrategui, J; Bannerman, DM; Bolam, JP; Brimblecombe, K; Cioroch, M; Connor-Robson, N; Cragg, SJ; Deltheil, T; Dodson, PD; Exley, R; Kaufmann, AK; Magill, PJ; Potgieter, D; Sloan, M; Threlfell, S; Wade-Martins, R; Wallings, R | 1 |
Bez, F; Cenci, MA; Francardo, V | 1 |
Rajput, AH; Rajput, EF | 1 |
Andersen, AD; Binzer, M; Blaabjerg, M; Gramsbergen, JBP; Kamal, A; Kjaer, TW; Stenager, E; Thagesen, H | 1 |
Almeida, L; Falcão, A; Fernandes-Lopes, C; Loureiro, AI; Nunes, T; Rocha, JF; Soares-da-Silva, P; Vaz-da-Silva, M; Wright, L | 1 |
Cantero, M; Cediel, R; Contreras, J; Montoliu, L; Murillo-Cuesta, S; Varela-Nieto, I; Zurita, E | 1 |
Abdel Wahab, Z; El-Moursy, SA; Rashed, L; Shawky, HM | 1 |
Allen, E; Carlson, KM; Cavanaugh, JE; Zigmond, MJ | 1 |
Hamamoto, M; Katayama, Y; Kumagai, T; Nagayama, H; Nishimura, S; Nishiyama, Y; Tsukamoto, K; Ueda, M | 1 |
Brunk, UT; Dunlop, RA; Rodgers, KJ | 1 |
Fink, GR; Lie, CH; Onur, ÖA; Piefke, M; Thiel, CM | 1 |
Abbs, JH; Bendlin, BB; Brooks, BR; Brown, WD; Chung, MK; Dejesus, OT; Dogan, S; Gallagher, CL; Holden, JE; Johnson, SC; Konopacki, RA; Nickles, RJ; Oakes, TR; Pyzalski, RW; Xu, G | 1 |
Pruett, BS; Salvatore, MF | 1 |
Ionov, ID; Severtsev, NN | 1 |
Kulkarni, N; Ledeen, RW; Lu, ZH; Wu, G | 1 |
Butler, SG; Feng, X; Kritchevsky, SB; Leng, I; Xu, Z; Zhang, T | 1 |
Bunzeck, N; Chowdhury, R; Dolan, RJ; Düzel, E; Guitart-Masip, M | 1 |
Gawel, D; Gawel, M; Jamrozik, Z; Kaminska, A; Rowińska-Marcińska, K; Slawek, J; Szmidt-Salkowska, E | 1 |
Fukumoto, D; Harada, N; Kakiuchi, T; Nishiyama, S; Satoh, K; Tsukada, H | 1 |
Nieoullon, A | 1 |
Froelick, GJ; Kim, DS; Palmiter, RD | 1 |
Ogawa, N | 1 |
Innis, SM; Ng, KF | 1 |
Giladi, N; Korczyn, AD; Merims, D; Peretz, C; Shabtai, H; Weizman, N | 1 |
Brown, AM; Colbran, RJ; Deutch, AY | 1 |
Bottiglieri, T; Diaz-Arrastia, R; Greenberg, SM; Growdon, JH; Gurol, ME; Hyman, BT; Irizarry, MC; Locascio, JJ; Raju, S; Tennis, M | 1 |
Staup, MA; Stehouwer, DJ | 1 |
Li, T; Malapani, C; Rakitin, BC; Scarmeas, N; Stern, Y | 1 |
Asada, T; Ito, H; Nozaki, S; Ota, M; Seki, C; Suhara, T; Yasuno, F | 1 |
Bae, E; Bang, S; Chun, B; Chung, J; Kang, J; Kim, J; Lee, S; Lee, Y; Paik, D | 1 |
Colebrooke, RE; Emson, PC; Humby, T; Lynch, PJ; McGowan, DP; Xia, J | 1 |
Abreu, P; Afonso-Oramas, D; Barroso-Chinea, P; Cruz-Muros, I; González, MC; Hernández, TG; Rodríguez, M | 1 |
Mash, DC; Papapetropoulos, S | 1 |
Pinho, MJ; Serrão, MP; Soares-da-Silva, P | 1 |
Erginöz, E; Ertan, S; Ertan, T; Kiziltan, G; Ozekmekçi, S | 1 |
Chen, JJ; Fernandez, HH | 1 |
Levy, G | 1 |
Segawa, M | 1 |
Breitenstein, C; Floel, A; Knecht, S; Lorenzen, A; Roesser, N; Vomhof, P | 1 |
Azulay, JP; Bourdeix, I; Durif, F; Rerat, K; Rogez, R; Tranchant, C | 1 |
Grahovska, T; Konstantinova, E; Petkov, VD; Petkov, VV | 1 |
Jellinger, K; Riederer, P; Tomonaga, M | 1 |
Itoh, H | 1 |
Fisman, M | 1 |
Walker, RF | 1 |
Masturzo, P; Murialdo, G; Nappi, G; Polleri, A; Sances, G; Savoldi, F | 1 |
Frackowiak, RS; Gibbs, JM; Jones, T; Lammertsma, AA; Leenders, KL | 1 |
Wilke, WL | 1 |
Praznikov, VP | 1 |
Parkes, JD | 1 |
Commissiong, JW | 2 |
Aikawa, E; Kawasaki, K; Mato, M; Ookawara, S | 1 |
Buterbaugh, GG; London, ED; Vocci, FJ; Waller, SB | 1 |
Cooper, RL; Linnoila, M | 2 |
Forman, LJ; Meites, J; Miki, N; Sonntag, WE | 1 |
Porter, JC; Reymond, MJ | 1 |
Houlihan, G; Miller, ST; Nerder, LJ; Papavasiliou, PS; Rao, SN; Stevens, JM; Thal, LJ | 1 |
Osuide, G; Wambebe, C | 1 |
Steger, RW | 1 |
Clough, CG; Mendoza, M; Yahr, MD | 1 |
Bone, AH; Taufek, HR | 1 |
Dregits, DP; Erinoff, L; Levine, TE; Seiden, LS | 1 |
Anisimov, VN; Dilman, VM | 1 |
Cano, J; de la Roza, C; Machado, A; Venero, JL | 1 |
Cano, J; Machado, A; Venero, JL | 2 |
Fernandes, MH; Guimarães, JT; Pestana, M; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
Chatel, DM; Dahdal, WY; Franson, KL; Grossberg, GT; Hay, DP; Kotegal, S; Mirza, WU; Neppe, V; Szwabo, PA | 1 |
McCrea, AE; Stehouwer, DJ; Van Hartesveldt, C | 2 |
Ghijsels, E; Moons, L; van Gils, J; Vandesande, F | 1 |
Dopico, AM; Zieher, LM | 1 |
Knoll, J | 1 |
Bowes, SG; Charlett, A; Dickins, J; Dobbs, RJ; Dobbs, SM; Frith, C; Henley, M | 1 |
Falk, M; Künig, G; Neubauer, M; Ransmayr, G; Wagner, M | 1 |
Battistin, L; Cagnin, A; Chierichetti, F; Dam, M; Fabbri, M; Ferlin, G; Pizzolato, G; Rossato, A | 1 |
Albani, M; Grigoriadis, N; Guiba-Tziampiri, O; Parashos, SA; Simeonidou, C | 1 |
Aihara, Y; Kanazawa, I; Murata, M; Yamada, S; Yamanouchi, H | 1 |
Bulygina, VV; Markel', AL; Maslova, LN; Naumenko, EV; Shishkina, GT | 1 |
Bodis-Wollner, I; Tagliati, M; Yahr, MD | 1 |
McEwen, ML; Stehouwer, DJ; Van Hartesveldt, C | 1 |
Kurth, MC | 1 |
Camicioli, R; Ganzini, L; Young, BK | 1 |
Playfer, JR | 1 |
Caffarri, G; Capretti, L; Chiodera, P; Cigarini, C; Coiro, V; Gramellini, D; Necchi Ghiri, S; Volpi, R | 1 |
Martí-Massó, JF | 1 |
Adler, CH; Atkinson, EJ; Boylan, KB; Caviness, JN; Finton, MJ; Goerss, SJ; Graff-Radford, NR; Kall, BA; Lucas, JA; Turk, MF; Uitti, RJ; Wharen, RE | 1 |
Mark, MH; Sage, JI | 1 |
Quinn, NP | 1 |
Andersen, SL; Dumont, NL; Teicher, MH | 1 |
Barbato, L; Berardelli, A; Nordera, G; Ruggieri, S; Stocchi, F | 1 |
Bertorello, AM; Finkel, Y; Soares-Da-Silva, P; Teixeira, VA; Vieira-Coelho, MA | 1 |
Ingvarsson, PE; Johnels, B; Olsson, T; Steg, G | 1 |
Guimaraes, JT; Hussain, T; Kansra, V; Lokhandwala, MF; Pestana, M; Serrao, MP; Soares-Da-Silva, P; Vieira-Coelho, MA | 1 |
Peng, Y; Shui, H; Tsai, Y; Wu, R | 1 |
Chang, CK; Cheng, JT; Chi, TC; Lee, JJ; Liu, IM; Yu, HJ | 1 |
Diroma, C; Fraddosio, A; Iliceto, G; Lamberti, S; Moramarco, A; Palagano, G; Zenzola, A | 1 |
Bettencourt, P; Cerqueira-Gomes, M; Correia, F; Ferreira, A; Martins, L; Pestana, M; Serrão, P; Soares-Da-Silva, P | 1 |
Hussain, T; Lokhandwala, MF; Serrão, P; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
Kleinow, J; Ramig, LO; Smith, A | 1 |
DeJesus, OT; Holden, JE; Nickles, RJ; Roberts, AD; Shelton, SE | 1 |
Arafah, BM; Biller, BM; Bonert, V; Chipman, JJ; Cook, DM; Hartman, ML; Kleinberg, DL; Samuels, MH; Stavrou, S; Zagar, A | 1 |
Hickey, MA; Morton, AJ; Reynolds, GP | 1 |
de Vries, JA; Fremouw-Ottevangers, DC; Muskiet, FA; van der Meulen, J; Wolthers, BG | 1 |
Blog, FB; Gilchrest, BA; Szabo, G | 1 |
Janoff, AS; Rosenberg, B | 1 |
Anisimov, VN; Dil'man, VM | 1 |
Berrios, N; Marshall, JF | 1 |
Matsuzawa, T | 1 |
Brandt, S; Cooper, RL; Linnoila, M | 1 |
Hendricks, SE; Lehman, JR; McArthur, DA | 1 |
Anisimov, VN; Dmitrievskaia, AIu; Gracheva, GM; Il'in, AP; Pozdeev, VK | 1 |
Alper, A; Dougher, GJ; Finch, CE; Hody, G; Jonec, V; Morton-Smith, W; Walker, JP | 1 |
Meites, J; Riegle, GD | 1 |
Fernandes, MH; Soares-da-Silva, P | 2 |
Horak, FB; Nashner, LM; Nutt, JG | 1 |
Coper, H; Hausmanowa-Petrusewicz, I; Kaminska, A; Ossowska, K; Schulze, G; Wolfarth, S | 1 |
Appel, SH; Bostwick, JR; Le, WD | 1 |
Allain, H; Bentue-Ferrer, D; Decombe, R; Lemaitre, MH; Martinet, JP; Milon, D | 1 |
Angelberger, P; Brücke, T; Deecke, L; Küfferle, B; Müller, C; Podreka, I; Topitz, A; Wenger, S | 1 |
Dluzen, D; McDermott, J | 1 |
Drucker-Colín, R; García-Hernández, F | 1 |
Greenspan, SL; Rowe, JW; Sparrow, D | 1 |
Joyce, JN; Neal, BS | 1 |
Bhatt, MH; Calne, DB; Martin, WR; Pate, BD; Ruth, TJ; Snow, BJ | 1 |
Dluzen, DE; McDermott, JL | 1 |
Da Prada, M | 1 |
Inoue, S; Numata, K; Saito, M; Shiraki, J; Shishido, T; Takamura, Y; Tanaka, K | 1 |
Flaster, E; Kostic, V; Przedborski, S; Sternic, N | 1 |
Bando, H; Saito, S; Takada, Y; Yamasaki, R; Zhang, C | 1 |
Garcia-Rill, E; Iwahara, T; Skinner, RD; Van Hartesveldt, C | 1 |
Dluzen, DE; McDermott, JL; Ramirez, VD | 2 |
Danilov, AA; Grigor'iants, RA; Kiseleva, ZM; Mukharliamov, NM | 1 |
Buu, NT; Debinski, W | 1 |
Bowes, SG; Deshmukh, AA; Dobbs, RJ; Dobbs, SM; Hughes, JR; Leeman, AL; Nicholson, PW; O'Neill, CJ | 1 |
Markel, AL; Maslova, LN; Naumenko, EV | 1 |
Ianovich, LA; Kuznetsova, SM; Man'kovskiĭ, NB; Red'ko, LA | 1 |
Gross, J; Horvath, G; Lun, A; Nagy, I; Szuecz, L | 1 |
Garty, M; Goldstein, DS; Kopin, IJ; Stull, R | 1 |
Diamond, SG; Hoehn, MM; Markham, CH; McDowell, FH; Muenter, MD | 1 |
Everest, H; George, CF; Monks, K; Renwick, AG; Robertson, DR; Waller, DG; Wood, ND | 1 |
Greer, M | 1 |
Leathwood, PD | 1 |
Atsumi, F; Iwamoto, K; Matsushita, T; Watanabe, J; Yamada, M | 1 |
Konstantinova, E; Petkov, VD; Petkov, VV; Popova, J | 1 |
Reed, JD; Schneider, EL | 1 |
Gancher, ST; Nutt, JG; Woodward, W | 1 |
LeWitt, PA | 1 |
Mortimer, JA | 1 |
Gottfries, CG | 1 |
Ribera Casado, JM | 1 |
Ermini, M; Finch, CE; Flurkey, K; Randall, PK; Sinha, YN | 1 |
Atsumi, F; Iwamoto, K; Watanabe, J | 1 |
Gordienko, NI; Markel', AL; Maslova, LN; Naumenko, EV | 1 |
Dontsov, VI | 1 |
De Keyser, J | 1 |
Calne, DB; Jaffe, M; Larsen, TA; LeWitt, PA; Newman, RP | 1 |
Hylka, VW; Meites, J; Sonntag, WE | 1 |
19 review(s) available for levodopa and Aging
Article | Year |
---|---|
Detoxification and antioxidative therapy for levodopa-induced neurodegeneration in Parkinson's disease.
Topics: Aging; Animals; Antioxidants; Antiparkinson Agents; Disease Progression; Dopamine Agonists; Humans; Inactivation, Metabolic; Levodopa; Nerve Degeneration; Oxidative Stress; Parkinson Disease | 2013 |
Dopamine and the regulation of cognition and attention.
Topics: Adult; Aged; Aging; Animals; Antiparkinson Agents; Attention; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Basal Ganglia; Child; Cognition; Cognition Disorders; Dopamine; Dopamine Agonists; Humans; Levodopa; Limbic System; Middle Aged; Models, Neurological; Models, Psychological; Parkinson Disease; Phylogeny; Receptors, Dopamine; Schizophrenic Psychology | 2002 |
[Etiology and physiopathology of patients with parkinson's disease].
Topics: Aging; Dopamine; Dopamine Agonists; Free Radicals; Humans; Levodopa; Ligases; Mutation; Nerve Tissue Proteins; Parkinson Disease; Synucleins; Ubiquitin-Protein Ligases | 2003 |
Community and long-term care management of Parkinson's disease in the elderly: focus on monoamine oxidase type B inhibitors.
Topics: Aged; Aging; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Catechol O-Methyltransferase Inhibitors; Dopamine Agonists; Homes for the Aged; Humans; Indans; Levodopa; Monoamine Oxidase Inhibitors; Nursing Homes; Parkinson Disease; Selegiline | 2007 |
The relationship of Parkinson disease with aging.
Topics: Aging; Antiparkinson Agents; Cognition Disorders; Dementia; Disease Progression; Gait; Humans; Levodopa; Parkinson Disease; Posture | 2007 |
Drug-induced tardive dyskinesia.
Topics: Aging; Antipsychotic Agents; Basal Ganglia Diseases; Diagnosis, Differential; Dyskinesia, Drug-Induced; Humans; Huntington Disease; Levodopa; Psychotic Disorders; Racial Groups; Sex Factors | 1981 |
Clinical pharmacology of senile dementia.
Topics: Aged; Aging; Anticoagulants; Arginine Vasopressin; Brain; Choline; Dementia; Dihydroergotoxine; Free Radicals; Glucose; Humans; Levodopa; Neurotransmitter Agents; Vasodilator Agents; Xanthinol Niacinate | 1981 |
Positron emission tomography of the brain: new possibilities for the investigation of human cerebral pathophysiology.
Topics: Aging; Amino Acids; Arterial Occlusive Diseases; Brain; Brain Ischemia; Brain Neoplasms; Carotid Artery Diseases; Cerebral Infarction; Cerebrovascular Disorders; Dementia; Epilepsy; Fluorine; Forecasting; Homeostasis; Humans; Huntington Disease; Isotopes; Levodopa; Mental Disorders; Models, Biological; Neurology; Oxygen Radioisotopes; Parkinson Disease; Radioisotopes; Receptors, Drug; Reference Values; Respiration; Tomography, Emission-Computed | 1984 |
Drug-induced seizures in the elderly. Causative agents and optimal management.
Topics: Aging; Anti-Bacterial Agents; Anti-Infective Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Central Nervous System Agents; Histamine H2 Antagonists; Humans; Lactams; Levodopa; Seizures; Substance Withdrawal Syndrome; Theophylline | 1995 |
The pharmacological basis of the beneficial effects of (-)deprenyl (selegiline) in Parkinson's and Alzheimer's diseases.
Topics: Aging; Alzheimer Disease; Animals; Avoidance Learning; Catalase; Corpus Striatum; Drug Therapy, Combination; Learning; Levodopa; Male; Neurons; Parkinson Disease; Rats; Selegiline; Substantia Nigra; Superoxide Dismutase | 1993 |
Using liquid levodopa in the treatment of Parkinson's disease. A practical guide.
Topics: Administration, Oral; Aging; Antiparkinson Agents; Central Nervous System; Gastric Emptying; Humans; Injections, Intravenous; Intestinal Absorption; Levodopa; Parkinson Disease; Solutions | 1997 |
Neuropsychiatric adverse effects of antiparkinsonian drugs. Characteristics, evaluation and treatment.
Topics: Aging; Akathisia, Drug-Induced; Amantadine; Antiparkinson Agents; Antipsychotic Agents; Cholinergic Antagonists; Delirium; Dementia; Depression; Dopamine Agonists; Electroconvulsive Therapy; Humans; Levodopa; Memantine; Monoamine Oxidase Inhibitors; Psychoses, Substance-Induced; Risk Factors; Serotonin Antagonists | 1997 |
Parkinson's disease.
Topics: Aged; Aging; Antiparkinson Agents; Humans; Levodopa; Parkinson Disease; Parkinson Disease, Secondary | 1997 |
[Drug-related motor disorders in aged people].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Aging; Antiparkinson Agents; Antipsychotic Agents; Calcium Channel Blockers; Humans; Levodopa; Psychomotor Disorders | 1997 |
Pharmacokinetics of continuous-release carbidopa/levodopa.
Topics: Aging; Antiparkinson Agents; Area Under Curve; Blood-Brain Barrier; Carbidopa; Delayed-Action Preparations; Drug Combinations; Gastric Emptying; Humans; Levodopa; Solubility | 1994 |
Sleep disorders in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Clinical Trials as Topic; Humans; Levodopa; Middle Aged; Motor Activity; Muscle, Skeletal; Parkinson Disease; Respiration; Sleep Wake Disorders | 1998 |
New approaches to the treatment of age-related brain disorders.
Topics: Aging; Alzheimer Disease; Benserazide; Benzophenones; Catechol O-Methyltransferase Inhibitors; Drug Combinations; Enzyme Inhibitors; Humans; Levodopa; Monoamine Oxidase Inhibitors; Nitrophenols; Parkinson Disease; Picolinic Acids; Tolcapone | 1991 |
[Dopaminergic mechanisms of brain aging (a review of the literature)].
Topics: Aging; Animals; Brain; Dopamine; Humans; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Receptors, Dopamine | 1989 |
Life extension.
Topics: Aged; Aging; Animals; Antioxidants; Dehydroepiandrosterone; Diet; Energy Intake; Ethics, Medical; Female; Free Radicals; Humans; Hypophysectomy; Immunocompetence; Levodopa; Life Expectancy; Longevity; Male; Meclofenoxate; Mice; Middle Aged; Models, Biological; Physical Exertion; Procaine; Superoxide Dismutase; Ubiquinone | 1985 |
12 trial(s) available for levodopa and Aging
Article | Year |
---|---|
Dopamine restores reward prediction errors in old age.
Topics: Adult; Aged; Aging; Alkaloids; Brain; Conditioning, Operant; Dopamine Agents; Double-Blind Method; Female; Humans; Image Processing, Computer-Assisted; Levodopa; Magnetic Resonance Imaging; Male; Oxygen; Reinforcement, Psychology; Reward; Time Factors; Young Adult | 2013 |
Modulatory effects of levodopa on cognitive control in young but not in older subjects: a pharmacological fMRI study.
Topics: Adult; Aged; Aging; Analysis of Variance; Brain Mapping; Catechol O-Methyltransferase; Cognition; Dopamine Agents; Double-Blind Method; Female; Functional Laterality; Humans; Image Processing, Computer-Assisted; Levodopa; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Oxygen; Prefrontal Cortex; Reaction Time; Young Adult | 2011 |
Dopamine modulates episodic memory persistence in old age.
Topics: Aged; Aging; Cohort Studies; Cross-Over Studies; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hippocampus; Humans; Levodopa; Magnetic Resonance Imaging; Male; Memory, Episodic; Photic Stimulation | 2012 |
Levodopa improves skilled hand functions in the elderly.
Topics: Adult; Aged; Aging; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Hand; Heart Rate; Humans; Levodopa; Male; Middle Aged; Motor Skills | 2008 |
Effect of age and disease duration on parkinsonian motor scores under levodopa therapy.
Topics: Adult; Aged; Aging; Antiparkinson Agents; Bromocriptine; Disease Progression; Female; Gait; Humans; Levodopa; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Psychomotor Performance; Tremor | 1995 |
Striatal dopamine D2 receptor alterations and response to L-DOPA in Parkinson's disease. A [123I]IBZM SPET study.
Topics: Adult; Age of Onset; Aged; Aging; Antiparkinson Agents; Disease Progression; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Middle Aged; Neostriatum; Parkinson Disease; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon | 1996 |
Altered neuroendocrine control of GH secretion in normal women of advanced reproductive age.
Topics: Adult; Aging; Dopamine Agonists; Female; GABA Agonists; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Levodopa; Middle Aged; Neurosecretory Systems; Reference Values; Reproduction; Serotonin Receptor Agonists; Sumatriptan; Valproic Acid | 1997 |
Sleep disorders in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Clinical Trials as Topic; Humans; Levodopa; Middle Aged; Motor Activity; Muscle, Skeletal; Parkinson Disease; Respiration; Sleep Wake Disorders | 1998 |
Sensitivity and specificity of six tests for the diagnosis of adult GH deficiency.
Topics: Adult; Aged; Aging; Arginine; Body Mass Index; Diagnostic Techniques, Endocrine; Drug Combinations; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Levodopa; Male; Metabolic Diseases; Middle Aged; Sensitivity and Specificity; Sex Characteristics; Stimulation, Chemical | 2002 |
Parkinsonian abnormality of foot strike: a phenomenon of ageing and/or one responsive to levodopa therapy?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Female; Gait; Humans; Levodopa; Male; Middle Aged; Parkinson Disease | 1990 |
The effect of age on the pharmacokinetics of levodopa administered alone and in the presence of carbidopa.
Topics: Administration, Oral; Adult; Aged; Aging; Carbidopa; Drug Interactions; Female; Humans; Injections, Intravenous; Levodopa; Male | 1989 |
Motor function in the normal aging population: treatment with levodopa.
Topics: Aged; Aging; Carbidopa; Dopamine; Drug Combinations; Humans; Levodopa; Middle Aged; Movement; Movement Disorders; Parkinson Disease | 1985 |
151 other study(ies) available for levodopa and Aging
Article | Year |
---|---|
DOPA Homeostasis by Dopamine: A Control-Theoretic View.
Topics: Aging; Dihydroxyphenylalanine; Dopamine; Homeostasis; Humans; Levodopa; Models, Neurological; Oxidative Stress; Tyrosine 3-Monooxygenase | 2021 |
Profiling the most elderly parkinson's disease patients: Does age or disease duration matter?
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Case-Control Studies; Clinical Protocols; Comorbidity; Disease Progression; Geriatrics; Humans; Levodopa; Middle Aged; Parkinson Disease; Patient Acuity; Thailand | 2021 |
Early derailment of firing properties in CA1 pyramidal cells of the ventral hippocampus in an Alzheimer's disease mouse model.
Topics: Action Potentials; Aging; Alzheimer Disease; Animals; CA1 Region, Hippocampal; Dopamine Agents; Dopaminergic Neurons; Electrophysiological Phenomena; Female; Levodopa; Male; Mice; Mice, Transgenic; Potassium Channels; Pyramidal Cells; Sodium Channels; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2022 |
Effects of L-DOPA on quadripulse magnetic stimulation-induced long-term potentiation in older adults.
Topics: Aged; Aging; Cross-Over Studies; Double-Blind Method; Humans; Levodopa; Long-Term Potentiation; Neuronal Plasticity; Transcranial Magnetic Stimulation | 2019 |
Frailty phenotype and the role of levodopa challenge test in geriatric inpatients with mild parkinsonian signs.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Benserazide; Case-Control Studies; Cross-Sectional Studies; Dopamine; Dopamine Agents; Drug Combinations; Female; Frail Elderly; Frailty; Geriatric Assessment; Geriatrics; Humans; Inpatients; Levodopa; Male; Parkinson Disease; Phenotype; Poland; Predictive Value of Tests; Prevalence; Severity of Illness Index | 2017 |
Parkinsonism without dopamine neuron degeneration in aged l-dopa-responsive dystonia knockin mice.
Topics: Aging; Analysis of Variance; Animals; Antiparkinson Agents; Dopamine Agents; Dopamine beta-Hydroxylase; Dopamine Plasma Membrane Transport Proteins; Dystonic Disorders; Female; Levodopa; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Parkinsonian Disorders; Tyrosine 3-Monooxygenase | 2017 |
Independent effects of age and levodopa on reversal learning in healthy volunteers.
Topics: Adult; Aged; Aging; Carbidopa; Cross-Over Studies; Dopamine Agonists; Double-Blind Method; Drug Combinations; Humans; Levodopa; Punishment; Reversal Learning; Reward; Young Adult | 2018 |
Bilateral subthalamic deep brain stimulation is an effective and safe treatment option for the older patients with Parkinson's disease.
Topics: Adult; Aged; Aging; Brain; Deep Brain Stimulation; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Subthalamic Nucleus; Treatment Outcome | 2018 |
Regional gray matter changes and age predict individual treatment response in Parkinson's disease.
Topics: Age Factors; Aged; Aging; Antiparkinson Agents; Brain; Female; Gray Matter; Humans; Levodopa; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Predictive Value of Tests; Treatment Outcome | 2019 |
Late aging-associated increases in L-DOPA-induced dyskinesia are accompanied by heightened neuroinflammation in the hemi-parkinsonian rat.
Topics: Aging; Animals; Dyskinesia, Drug-Induced; Gene Expression; Inflammation; Interleukin-1beta; Interleukin-6; Levodopa; Male; Parkinson Disease; Rats; Rats, Inbred F344; Risk Factors | 2019 |
Dopamine and the cost of aging.
Topics: Aging; Conditioning, Operant; Dopamine Agents; Female; Humans; Levodopa; Male; Reward | 2013 |
Levodopa, vitamins, ageing and the neuropathy of Parkinson's disease.
Topics: Adult; Aged; Aging; Antiparkinson Agents; Cross-Sectional Studies; Female; Folic Acid; Humans; Levodopa; Male; Middle Aged; Nervous System Diseases; Parkinson Disease; Vitamin B 12 | 2013 |
Dopamine as the fountain of youth? Restoring decision making ability in older adults.
Topics: Aging; Conditioning, Operant; Dopamine Agents; Female; Humans; Levodopa; Male; Reward | 2013 |
Age-dependent dopaminergic dysfunction following fetal exposure to atrazine in SD rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Atrazine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Fetus; Herbicides; Homovanillic Acid; Levodopa; Maternal-Fetal Exchange; Nuclear Receptor Subfamily 4, Group A, Member 2; Pregnancy; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2014 |
Age-related decline in the responsiveness of motor cortex to plastic forces reverses with levodopa or cerebellar stimulation.
Topics: Adult; Aged; Aging; Cerebellum; Dopamine; Evoked Potentials; Female; Humans; Levodopa; Male; Middle Aged; Motor Cortex; Motor Skills; Neuronal Plasticity; Psychomotor Performance; Synaptic Transmission; Transcranial Direct Current Stimulation; Young Adult | 2014 |
Interrogating the aged striatum: robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integration.
Topics: Aging; Amphetamine; Animals; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopaminergic Neurons; Dyskinesia, Drug-Induced; Embryo, Mammalian; Functional Laterality; Levodopa; Neurites; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; Recovery of Function; Stem Cell Transplantation; Substance P | 2015 |
Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients.
Topics: Adult; Aged; Aged, 80 and over; Aging; DNA Methylation; Epigenesis, Genetic; Female; Granulocytes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Risk Factors | 2015 |
LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function.
Topics: Action Potentials; Aging; Amino Acid Substitution; Animals; Antiparkinson Agents; Cell Death; Chromosomes, Artificial, Bacterial; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Female; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Male; Mutation; Parkinson Disease; Promoter Regions, Genetic; Protein Domains; Rats; Rats, Transgenic; Substantia Nigra | 2016 |
Dramatic differences in susceptibility to l-DOPA-induced dyskinesia between mice that are aged before or after a nigrostriatal dopamine lesion.
Topics: Aging; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Levodopa; Mice, Inbred C57BL; Motor Activity; Oxidopamine; Parkinson Disease | 2016 |
Octogenarian parkinsonism - Clinicopathological observations.
Topics: Aged, 80 and over; Aging; Antiparkinson Agents; Autopsy; Brain; Disease Progression; Female; Humans; Levodopa; Longitudinal Studies; Male; Parkinsonian Disorders | 2017 |
Cerebrospinal fluid levels of catecholamines and its metabolites in Parkinson's disease: effect of l-DOPA treatment and changes in levodopa-induced dyskinesia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aging; Antiparkinson Agents; Catecholamines; Dopamine; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Norepinephrine; Parkinson Disease | 2017 |
Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects.
Topics: Adult; Aged; Aging; Antiparkinson Agents; Drug Administration Schedule; Female; Humans; Levodopa; Male; Resveratrol; Stilbenes; Young Adult | 2009 |
Melanin precursors prevent premature age-related and noise-induced hearing loss in albino mice.
Topics: Aging; Aging, Premature; Albinism; Albinism, Oculocutaneous; Animals; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Hearing Loss, Noise-Induced; Hearing Loss, Sensorineural; Levodopa; Melanins; Mice; Mice, Transgenic; Monophenol Monooxygenase; Tyrosine 3-Monooxygenase | 2010 |
The effect of memantine and levodopa/carbidopa on the responses of phrenic nerve-diaphragm preparations from aged rats.
Topics: Aging; Animals; Carbidopa; Diaphragm; Electric Stimulation; Gallamine Triethiodide; Gene Expression Regulation; Levodopa; Male; Memantine; Muscle Contraction; Neostigmine; Neuromuscular Blockade; Phrenic Nerve; Protein Subunits; Rats; Receptors, Nicotinic; RNA, Messenger | 2009 |
L-DOPA reverses motor deficits associated with normal aging in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Brain Chemistry; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Psychomotor Performance | 2011 |
Influence of ageing on the pharmacokinetics of levodopa in elderly patients with Parkinson's disease.
Topics: Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Female; Humans; Levodopa; Male; Parkinson Disease; Statistics, Nonparametric; Time Factors | 2011 |
Proteins containing oxidized amino acids induce apoptosis in human monocytes.
Topics: Aging; Annexin A5; Apoptosis; Caspase 3; Cell Line; Ceroid; DNA Fragmentation; Enzyme Activation; Humans; Intracellular Membranes; Levodopa; Lipofuscin; Lysosomes; Membrane Potential, Mitochondrial; Mitochondrial Membranes; Monocytes; Oxidation-Reduction; Permeability; Protein Biosynthesis; Tyrosine | 2011 |
A longitudinal study of motor performance and striatal [18F]fluorodopa uptake in Parkinson's disease.
Topics: Aged; Aging; Antiparkinson Agents; Carbidopa; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Female; Hand Strength; Humans; Isometric Contraction; Levodopa; Longitudinal Studies; Male; Middle Aged; Muscle Strength; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Psychomotor Performance; Radiopharmaceuticals; Reaction Time; Retrospective Studies; Sex Characteristics; Tongue | 2011 |
Dichotomy of tyrosine hydroxylase and dopamine regulation between somatodendritic and terminal field areas of nigrostriatal and mesoaccumbens pathways.
Topics: Aging; Animals; Dendrites; Dopamine; Hydrazines; Levodopa; Male; Neostriatum; Neural Pathways; Nucleus Accumbens; Phosphorylation; Phosphoserine; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2012 |
Histamine- and haloperidol-induced catalepsy in aged mice: differential responsiveness to L-DOPA.
Topics: Aging; Animals; Antiparkinson Agents; Catalepsy; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Histamine; Injections, Intraventricular; Levodopa; Male; Mice; Mice, Inbred BALB C; Parkinson Disease; Time Factors | 2012 |
Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Aging; Animals; Antiparkinson Agents; Blotting, Western; Cell Count; Dopamine; Dopaminergic Neurons; Female; G(M1) Ganglioside; Gangliosides; Humans; Immunohistochemistry; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Acetylgalactosaminyltransferases; Parkinson Disease; Polypeptide N-acetylgalactosaminyltransferase; Synucleins; Tyrosine 3-Monooxygenase | 2012 |
Effects of aging and levodopa on the laryngeal adductor reflex in rats.
Topics: Aging; Animals; Dopamine Agents; Dopaminergic Neurons; Laryngeal Muscles; Laryngeal Nerves; Levodopa; Male; Rats; Rats, Inbred F344; Reaction Time; Reflex | 2012 |
Electrophysiological features of lower motor neuron involvement in progressive supranuclear palsy.
Topics: Action Potentials; Aged; Aging; Antiparkinson Agents; Electrodiagnosis; Electromyography; Female; Humans; Levodopa; Male; Middle Aged; Motor Neuron Disease; Motor Neurons; Muscle, Skeletal; Neural Conduction; Peripheral Nerves; Supranuclear Palsy, Progressive | 2013 |
Age-related changes in the striatal dopaminergic system in the living brain: a multiparametric PET study in conscious monkeys.
Topics: Aging; Animals; Benzazepines; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extracellular Space; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Microdialysis; Piperazines; Raclopride; Tomography, Emission-Computed | 2002 |
Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum.
Topics: Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Body Weight; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Immunohistochemistry; Levodopa; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Opioid, mu; Signal Transduction; Sodium Chloride | 2002 |
Behavioral responses are altered in piglets with decreased frontal cortex docosahexaenoic acid.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Brain; Diet; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Dopamine; Dopamine D2 Receptor Antagonists; Energy Intake; Fatty Acids; Fatty Acids, Unsaturated; Frontal Lobe; Levodopa; Male; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Sulpiride; Swine; Weight Gain | 2003 |
Antiparkinsonian medication is not a risk factor for the development of hallucinations in Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Dementia; Female; Hallucinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Retrospective Studies; Risk Factors; United Kingdom | 2004 |
Dopamine depletion alters phosphorylation of striatal proteins in a model of Parkinsonism.
Topics: Aging; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Levodopa; Male; Nerve Tissue Proteins; Neural Pathways; Neuronal Plasticity; Parkinsonian Disorders; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Presynaptic Terminals; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Substantia Nigra; Synaptic Membranes; Up-Regulation | 2005 |
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12 | 2005 |
Ontogeny of L-DOPA-induced locomotion: Expression of c-Fos in the brainstem and basal ganglia of rats.
Topics: Aging; Animals; Arousal; Basal Ganglia; Brain Stem; Data Interpretation, Statistical; Dopamine Agents; Genes, fos; Immunohistochemistry; Levodopa; Locomotion; Male; Prosencephalon; Rats; Rats, Sprague-Dawley | 2006 |
Single-dose levodopa administration and aging independently disrupt time production.
Topics: Adult; Aged; Aged, 80 and over; Aging; Choice Behavior; Dopamine; Female; Humans; Levodopa; Male; Placebos; Reaction Time; Time Perception | 2006 |
Age-related decline of dopamine synthesis in the living human brain measured by positron emission tomography with L-[beta-11C]DOPA.
Topics: Adult; Aged; Aging; Brain; Dopamine; Humans; Levodopa; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography | 2006 |
Loss of spastic paraplegia gene atlastin induces age-dependent death of dopaminergic neurons in Drosophila.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Animals, Genetically Modified; Cell Death; Cell Proliferation; Dopamine; Dopamine Agonists; Drosophila; Drosophila Proteins; Embryo, Nonmammalian; Gene Expression Regulation; Green Fluorescent Proteins; GTP Phosphohydrolases; GTP-Binding Proteins; Levodopa; Male; Membrane Proteins; Neurons; Sequence Alignment; Tyrosine 3-Monooxygenase | 2008 |
Age-related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease.
Topics: Aging; Animals; Antiparkinson Agents; Blotting, Western; Corpus Striatum; Disease Models, Animal; Dopamine; Immunohistochemistry; Levodopa; Male; Mice; Mice, Mutant Strains; Motor Activity; Motor Skills; Nerve Degeneration; Parkinson Disease; Phosphorylation; Substantia Nigra; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2006 |
Aging of the rat mesostriatal system: differences between the nigrostriatal and the mesolimbic compartments.
Topics: Aging; alpha-Synuclein; Amyloid beta-Protein Precursor; Animals; Axons; Corpus Striatum; Dopa Decarboxylase; Dopamine; Levodopa; Limbic System; Male; Nerve Degeneration; Phosphorylation; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 2007 |
Motor fluctuations and dyskinesias in advanced/end stage Parkinson's disease: a study from a population of brain donors.
Topics: Age of Onset; Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Brain; Cohort Studies; Disease Progression; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Nerve Degeneration; Neuronal Plasticity; Parkinson Disease; Synaptic Transmission; Tissue Donors | 2007 |
High-salt intake and the renal expression of amino acid transporters in spontaneously hypertensive rats.
Topics: Aging; Amino Acid Transport System ASC; Amino Acid Transport System y+; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Dopamine; Dose-Response Relationship, Drug; Fusion Regulatory Protein 1, Light Chains; Hypertension; Kidney; Kidney Tubules; Large Neutral Amino Acid-Transporter 1; Levodopa; Minor Histocompatibility Antigens; Neurotransmitter Agents; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Sodium Chloride, Dietary | 2007 |
Relationship between age and subtypes of psychotic symptoms in Parkinson's disease.
Topics: Age of Onset; Aged; Aging; Antiparkinson Agents; Delusions; Female; Hallucinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Statistics, Nonparametric | 2007 |
[Segawa disease].
Topics: Aging; Brain; Dopamine; Dystonia; Female; GTP Cyclohydrolase; History, 20th Century; Humans; Levodopa; Phenotype; Pteridines | 2008 |
[Precoce survey: a new self-assessment patient card for early detection and management of Parkinson disease fluctuations].
Topics: Adult; Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Reproducibility of Results; Surveys and Questionnaires | 2008 |
Enkephalin receptor changes in rat brain during aging.
Topics: Aging; Animals; Cerebral Cortex; Corpus Striatum; Haloperidol; Hypothalamus; Levodopa; Male; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Progressive supranuclear palsy: clinico-pathological and biochemical studies.
Topics: Adolescent; Adult; Aged; Aging; Brain; Brain Chemistry; Bulbar Palsy, Progressive; Female; Humans; Levodopa; Male; Middle Aged; Tyrosine 3-Monooxygenase | 1980 |
Reinstatement of LH surges by serotonin neuroleptics in aging, constant estrous rats.
Topics: 5-Hydroxytryptophan; Aging; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Castration; Estradiol; Estrus; Female; Fenclonine; Levodopa; Luteinizing Hormone; Methyltyrosines; Muridae; Pargyline; Pregnancy; Progesterone; Serotonin | 1982 |
Neuroendocrinological signs of central neurotransmission disorders.
Topics: Aging; Central Nervous System Diseases; Endocrine System Diseases; Headache; Humans; Levodopa; Neurotransmitter Agents; Nociceptors; Nomifensine; Periodicity; Prolactin | 1983 |
Age-dependent depressor effect of L-dopa in dogs with inhibition of extracerebral dopa decarboxylase.
Topics: Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain; Carbidopa; Dogs; Drug Therapy, Combination; Heart Rate; Levodopa; Male; Renin; Renin-Angiotensin System; Time Factors | 1983 |
[Adrenergic mechanisms regulating the motor reactions of rats in the early postnatal period].
Topics: Aging; Animals; Animals, Newborn; Chlorpromazine; Levodopa; Motor Activity; Rats; Receptors, Adrenergic; Reserpine | 1984 |
Variability in Parkinson's disease; clinical aspects, causes and treatment.
Topics: Aging; Fatigue; Humans; Levodopa; Movement Disorders; Neurasthenia; Parkinson Disease; Sleep | 1983 |
The development of catecholaminergic nerves in the spinal cord of rat. II. Regional development.
Topics: Aging; Animals; Dopamine; Female; Fetus; Levodopa; Microscopy, Fluorescence; Norepinephrine; Pregnancy; Rats; Spinal Cord | 1983 |
Synthesis of catecholamines in the developing spinal cord of the rat.
Topics: Aging; Animals; Dopamine; Kinetics; Levodopa; Nialamide; Norepinephrine; Rats; Rats, Inbred Strains; Spinal Cord | 1984 |
Studies on fluorescent granular perithelium (F.G.P.) of rat cerebral cortex - especially referring to morphological changes in aging.
Topics: 5-Hydroxytryptophan; Aging; Animals; Animals, Newborn; Blood Vessels; Cerebral Cortex; Dioxoles; Levodopa; Microscopy, Fluorescence; Rats; Serotonin | 1981 |
Age-dependent reduction in maximum electroshock convulsive threshold associated with decreased concentrations of brain monoamines.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Aging; Animals; Biogenic Amines; Brain Chemistry; Electroshock; Female; Hydroxydopamines; Levodopa; p-Chloroamphetamine; Pregnancy; Rats; Rats, Inbred Strains; Seizures; Tetrabenazine | 1982 |
Effects of centrally and systemically administered L-tyrosine and L-leucine on ovarian function in the old rat.
Topics: Aging; Animals; Catecholamines; Estrus; Female; Leucine; Levodopa; Ovary; Pregnancy; Preoptic Area; Rats; Serotonin; Tyrosine | 1980 |
Maintenance by L-DOPA treatment of estrous cycles and LH response to estrogen in aging female rats.
Topics: Aging; Animals; Castration; Estradiol; Estrus; Female; Hypothalamo-Hypophyseal System; Levodopa; Luteinizing Hormone; Pituitary-Adrenal System; Pregnancy; Prolactin; Rats | 1980 |
Secretion of hypothalamic dopamine into pituitary stalk blood of aged female rats.
Topics: Aging; Animals; Dopamine; Estrus; Female; Hypothalamus; Levodopa; Median Eminence; Pituitary Gland; Pregnancy; Prolactin; Rats; Tyrosine | 1981 |
Age-related motor and catecholamine alterations in mice on levodopa supplemented diet.
Topics: Aging; Animals; Brain Chemistry; Catecholamines; Diet; Levodopa; Male; Mice; Motor Activity; Quinuclidinyl Benzilate; Receptors, Dopamine; Receptors, Muscarinic; Spiperone | 1981 |
Hypothermic effect of dopamine and L-DOPA in the domestic fowl (Gallus domesticus).
Topics: Aging; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Body Temperature; Chickens; Depression, Chemical; Dopamine; Drug Interactions; Levodopa; Male | 1981 |
Age related changes in the control of prolactin secretion in the female rat.
Topics: Aging; Animals; Castration; Dopamine; Estrogens; Female; Hypothalamus; Levodopa; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1981 |
A case of sporadic juvenile Parkinson's disease.
Topics: Adult; Aging; Carbidopa; Female; Humans; Levodopa; Parkinson Disease | 1981 |
Influence of exogenous L-3,4,-dihydroxyphenylalanine (L-dopa) on the methionine and s-adenosylmethionine concentrations in the brain and other tissues [proceedings].
Topics: Aging; Animals; Brain; Iproniazid; Kidney; Levodopa; Liver; Methionine; Organ Specificity; Rats; S-Adenosylmethionine | 1980 |
Effects of neonatal and adult 6-hydroxydopamine treatment on random-interval behavior.
Topics: Aging; Animals; Animals, Newborn; Apomorphine; Brain Chemistry; Catecholamines; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Hydroxydopamines; Levodopa; Male; Mice; Rats; Reinforcement Schedule; Time Factors | 1980 |
Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice.
Topics: Adenocarcinoma; Aging; Animals; Female; Leukemia, Experimental; Levodopa; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Phenformin; Phenytoin | 1980 |
Age-related changes on monoamine turnover in hippocampus of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Hippocampus; Hydroxyindoleacetic Acid; Immunohistochemistry; Levodopa; Male; Monoamine Oxidase; Norepinephrine; Rats; Rats, Wistar; Serotonin | 1993 |
Effect of ageing on monoamine turnover in the prefrontal cortex of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pargyline; Prefrontal Cortex; Probenecid; Rats; Rats, Wistar; Serotonin; Tyrosine 3-Monooxygenase | 1993 |
Ontogeny of the cell outward dopamine transporter in canine renal tissues.
Topics: Aging; Animals; Animals, Newborn; Aromatic-L-Amino-Acid Decarboxylases; Carrier Proteins; Dogs; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Kidney; Kinetics; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins | 1995 |
L-dopa-induced air-stepping in preweanling rats. I. Effects of dose and age.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Gait; Levodopa; Male; Motor Activity; Rats; Stereotyped Behavior | 1994 |
L-dopa-induced air-stepping in preweanling rats. II. Kinematic analyses.
Topics: Aging; Animals; Female; Forelimb; Gait; Hindlimb; Levodopa; Male; Motor Activity; Rats; Stereotyped Behavior; Time Factors; Videotape Recording | 1994 |
Immunocytochemical localization of L-dopa and dopamine in the brain of the chicken (Gallus domesticus).
Topics: Aging; Animals; Brain Chemistry; Chickens; Dopamine; Female; Immunohistochemistry; Levodopa; Nerve Endings | 1994 |
Neurochemical characterization of the alterations in the noradrenergic afferents to the cerebellum of adult rats exposed to X-irradiation at birth.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Afferent Pathways; Aging; Animals; Animals, Newborn; Cerebellar Cortex; Cerebellum; Female; In Vitro Techniques; Kinetics; Levodopa; Male; Norepinephrine; Rats; Rats, Wistar; Reserpine; Tritium; Tyrosine 3-Monooxygenase | 1993 |
Hypothesis: the bradyphrenia of parkinsonism is a nosological entity.
Topics: Adult; Aged; Aging; Alcohol Drinking; Antiparkinson Agents; Cognition; Cognition Disorders; Depressive Disorder; Ethanol; Female; Humans; Levodopa; Male; Middle Aged; Motor Skills; Parkinson Disease; Probability; Psychological Tests; Reaction Time | 1993 |
Ontogenetic development of the locomotor response to levodopa in the rat.
Topics: Aging; Animals; Animals, Newborn; Autoreceptors; Brain; Female; Injections, Intraperitoneal; Levodopa; Locomotion; Male; Motor Activity; Norepinephrine; Rats; Receptors, Dopamine | 1996 |
Age-related decrease in responsiveness to L-DOPA is not due to changes in dopamine receptor mRNAs or G protein mRNAs.
Topics: Actins; Aged; Aged, 80 and over; Aging; Antiparkinson Agents; Blotting, Northern; Brain Chemistry; Female; GTP-Binding Proteins; Humans; In Vitro Techniques; Levodopa; Male; Middle Aged; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger | 1996 |
[Brain catecholamines and the hypothalamo-hypophyseal-adrenocortical system in hereditary arterial hypertension].
Topics: Aging; Animals; Blood Pressure; Brain; Brain Chemistry; Carbidopa; Catecholamines; Dopamine Agonists; Drug Combinations; Female; Hypertension; Hypothalamo-Hypophyseal System; Levodopa; Male; Pituitary-Adrenal System; Rats; Rats, Inbred SHR; Rats, Wistar; Stress, Psychological | 1996 |
The pattern electroretinogram in Parkinson's disease reveals lack of retinal spatial tuning.
Topics: Aged; Aged, 80 and over; Aging; Disease Progression; Electroretinography; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Reference Values; Retina; Space Perception; Time Perception; Visual Perception | 1996 |
A kinematic comparison of L-DOPA-induced air-stepping and swimming in developing rats.
Topics: Aging; Animals; Animals, Newborn; Dopamine Agents; Female; Levodopa; Locomotion; Male; Motor Activity; Motor Skills; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Swimming | 1997 |
Unilateral pallidotomy for Parkinson's disease: comparison of outcome in younger versus elderly patients.
Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Globus Pallidus; Humans; Levodopa; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Postoperative Complications; Severity of Illness Index; Treatment Outcome | 1997 |
Parkinson's disease: clinical features.
Topics: Aging; Antiparkinson Agents; Diagnosis, Differential; Humans; Levodopa; Neurologic Examination; Parkinson Disease; Parkinson Disease, Secondary; Treatment Outcome | 1997 |
The developing prefrontal cortex: is there a transient interneuron that stimulates catecholamine terminals?
Topics: Aging; Animals; Catecholamines; Interneurons; Levodopa; Nerve Endings; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Tissue Distribution | 1998 |
Dopamine-dependent inhibition of jejunal Na+-K+-ATPase during high-salt diet in young but not in adult rats.
Topics: Absorption; Adenosine Triphosphate; Aging; Animals; Diet, Sodium-Restricted; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Hydrolysis; Intestinal Mucosa; Jejunum; Levodopa; Norepinephrine; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Sodium; Sodium-Potassium-Exchanging ATPase | 1998 |
Objective assessment in Parkinson's disease: optoelectronic movement and force analysis in clinical routine and research.
Topics: Aging; Antiparkinson Agents; Dopamine Agonists; Electronics; Hand; Hand Strength; Humans; Levodopa; Methods; Movement; Optics and Photonics; Parkinson Disease; Posture; Reference Values; Tremor | 1999 |
Aging, high salt intake, and renal dopaminergic activity in Fischer 344 rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Aromatic-L-Amino-Acid Decarboxylases; Catecholamines; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Kidney; Levodopa; Male; Monoamine Oxidase; Rats; Rats, Inbred F344; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase | 1999 |
Evaluation of L-DOPA biotransformation during repeated L-DOPA infusion into the striatum in freely-moving young and old rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antiparkinson Agents; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Locomotion; Male; Microdialysis; Rats; Rats, Wistar | 2000 |
Changes in endogenous monoamines in aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Catechol O-Methyltransferase; Cerebral Cortex; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Monoamine Oxidase; Norepinephrine; Rats; Rats, Wistar; Serotonin | 2001 |
Efficacy and tolerability of dopamine agonists in a parkinsonian population.
Topics: Age of Onset; Aged; Aging; Benzothiazoles; Bromocriptine; Dopamine Agonists; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Ergolines; Female; Follow-Up Studies; Humans; Indoles; Levodopa; Lisuride; Male; Middle Aged; Parkinson Disease; Pergolide; Pramipexole; Retrospective Studies; Thiazoles; Treatment Outcome | 2001 |
Heart failure, aging, and renal synthesis of dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Age Factors; Aged; Aging; Aldosterone; Cardiac Output, Low; Case-Control Studies; Creatinine; Diet, Sodium-Restricted; Dopamine; Echocardiography; Female; Homovanillic Acid; Humans; Kidney; Levodopa; Male; Middle Aged; Norepinephrine; Statistics as Topic; Urine | 2001 |
Salt intake and intestinal dopaminergic activity in adult and old Fischer 344 rats.
Topics: Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dopamine; Jejunum; Levodopa; Male; Rats; Rats, Inbred F344; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 2001 |
Speech motor stability in IPD: effects of rate and loudness manipulations.
Topics: Aged; Aging; Antiparkinson Agents; Dysarthria; Female; Humans; Levodopa; Lip; Loudness Perception; Male; Mandible; Middle Aged; Parkinson Disease; Severity of Illness Index; Speech | 2001 |
Effect of tetrabenazine on the striatal uptake of exogenous L-DOPA in vivo: a PET study in young and aged rhesus monkeys.
Topics: Adrenergic Uptake Inhibitors; Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; Dopamine Agents; Image Processing, Computer-Assisted; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Neuropeptides; Tetrabenazine; Tomography, Emission-Computed; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2002 |
The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease.
Topics: Aging; Animals; Behavior, Animal; Brain; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Huntington Disease; Levodopa; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Spatial Behavior; Survival Rate | 2002 |
Determination of some L-3,4-dihydroxyphenylalanine and dopamine metabolites in urine by means of mass fragmentography.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Adult; Aging; Child; Child, Preschool; Dihydroxyphenylalanine; Dopamine; Flavoring Agents; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Infant; Infant, Newborn; Lactates; Levodopa; Middle Aged; Neuroblastoma; Phenylethyl Alcohol | 1978 |
Effects of aging and chronic sun exposure on melanocytes in human skin.
Topics: Adult; Aged; Aging; Cell Count; Humans; Levodopa; Male; Melanocytes; Middle Aged; Skin; Staining and Labeling; Sunlight | 1979 |
Chemically evoked hypothermia in the mouse: towards a method for investigating thermodynamic parameters of aging and death in mammals.
Topics: Adaptation, Physiological; Aging; Animals; Chlorpromazine; Drug Synergism; Female; Fenclonine; Hypothermia; Levodopa; Male; Methods; Mice; Mice, Inbred ICR; Reserpine; Sex Factors; Thermodynamics | 1978 |
[Increase in longevity and a decrease in the frequency of tumors in C3H/Sn mice under the influence of fenformin and diphenin].
Topics: Aging; Animals; Female; Levodopa; Longevity; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Phenformin; Phenytoin; Time Factors | 1979 |
Movement disorders of aged rats: reversal by dopamine receptor stimulation.
Topics: Aging; Animals; Apomorphine; Levodopa; Male; Movement Disorders; Rats; Receptors, Dopamine; Swimming; Time Factors | 1979 |
Effect of L-dopa on the ovary of aged hens.
Topics: Aging; Animals; Body Weight; Chickens; Feathers; Female; Injections, Subcutaneous; Levodopa; Ovary; Oviducts; Ovulation | 1979 |
Reinstatement of ovarian cycles in aged female rats by placement of L-dopa in the medial preoptic area [proceedings].
Topics: Aging; Animals; Female; Levodopa; Ovary; Periodicity; Preoptic Area; Rats | 1978 |
Pharmacological induction of ovulation in old and neonatally androgenized rats.
Topics: Aging; Animals; Animals, Newborn; Brain; Female; Iproniazid; Levodopa; Ovulation; Ovulation Induction; Progesterone; Rats; Receptors, Steroid; Testosterone | 1978 |
[Age and changes in the levels of biogenic amines in the brains of rats].
Topics: Age Factors; Aging; Animals; Biogenic Amines; Brain Chemistry; Brain Stem; Dopamine; Histamine; Hydroxyindoleacetic Acid; Levodopa; Male; Norepinephrine; Rats; Serotonin; Sexual Maturation | 1977 |
Reinstatement of vaginal cycles in aged female rats.
Topics: Aging; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drug Interactions; Estrus; Female; Fusaric Acid; Hypophysectomy; Levodopa; Phenoxybenzamine; Pimozide; Pregnancy; Propranolol; Rats; Tyrosine; Vagina | 1976 |
Aging and the passage of L-tyrosine, L-DOPA, and inulin into mouse brain slices in vitro.
Topics: Aging; Animals; Biological Transport, Active; Brain; Brain Stem; Corpus Striatum; Hypothalamus; In Vitro Techniques; Inulin; Levodopa; Male; Mice; Mice, Inbred C57BL; Tritium; Tyrosine | 1975 |
Effects of aging on LH and prolactin after LHRL L-dopa, methyl-dopa, and stress in male rat.
Topics: Aging; Animals; Hypothalamus; Levodopa; Luteinizing Hormone; Male; Methyldopa; Pituitary Gland, Anterior; Prolactin; Rats; Stress, Physiological | 1976 |
Effect of alpha-human atrial natriuretic peptide on the synthesis of dopamine in the rat kidney.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Aging; Animals; Atrial Natriuretic Factor; Dopamine; In Vitro Techniques; Kidney; Levodopa; Male; Purinones; Rats; Rats, Inbred Strains; Sodium, Dietary | 1992 |
Postural inflexibility in parkinsonian subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Electromyography; Female; Humans; Levodopa; Male; Middle Aged; Muscles; Parkinson Disease; Postural Balance; Posture; Reflex | 1992 |
Muscle stiffness and continuous electromyographic activity in old rats; an animal model for spasticity?
Topics: Aging; Animals; Atrophy; Baclofen; Benserazide; Drug Combinations; Electromyography; Female; Levodopa; Muscle Contraction; Muscle Denervation; Muscle Spasticity; Muscle Tonus; Muscles; Rats; Rats, Wistar | 1992 |
Use of [3H]-GBR12935 to measure dopaminergic nerve terminal growth into the developing rat striatum.
Topics: Aging; Animals; Biological Transport; Corpus Striatum; Dopamine; Embryonic and Fetal Development; Gestational Age; Levodopa; Male; Nerve Endings; Piperazines; Rats; Rats, Inbred Strains; Tritium | 1992 |
Cardiac beta-adrenoceptor sensitivity and Parkinson's disease.
Topics: Aged; Aging; Blood Pressure; Bromocriptine; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Isoproterenol; Levodopa; Male; Middle Aged; Myocardium; Parkinson Disease; Piribedil; Receptors, Adrenergic, beta | 1991 |
Dopamine D2 receptor imaging with SPECT: studies in different neuropsychiatric disorders.
Topics: Adult; Aged; Aging; Antipsychotic Agents; Benzamides; Brain Diseases; Cerebellum; Corpus Striatum; Frontal Lobe; Humans; Huntington Disease; Iodine Radioisotopes; Levodopa; Middle Aged; Parkinson Disease; Pyrrolidines; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 1991 |
Age effects on monoamine turnover of the rat substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydrazines; In Vitro Techniques; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra | 1991 |
Striatal dopamine release in vitro from immature male rats shows enhanced responsiveness to pulsatile, but not continuous, infusions of L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Levodopa; Male; Pulsatile Flow; Rats; Rats, Inbred Strains | 1991 |
A study on the renal synthesis of dopamine in aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Chromatography, High Pressure Liquid; Dopamine; Kidney; Levodopa; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1991 |
A new motor test sensitive to aging and dopaminergic function.
Topics: Aging; Animals; Body Weight; Dextroamphetamine; Dopamine; Haloperidol; Levodopa; Male; Motor Activity; Neuropsychological Tests; Rats; Rats, Inbred Strains | 1991 |
Dopaminergic regulation of gonadotropin and thyrotropin hormone secretion is altered with age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Dopamine; Follicle Stimulating Hormone; Growth Hormone; Humans; Levodopa; Luteinizing Hormone; Male; Middle Aged; Prolactin; Thyrotropin | 1991 |
Dopamine D1 receptor behavioral responsitivity following selective lesions of the striatal patch compartment during development.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Analysis of Variance; Animals; Animals, Newborn; Apomorphine; Autoradiography; Corpus Striatum; Haloperidol; Hydroxydopamines; Levodopa; Mazindol; Motor Activity; Neurotoxins; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior; Tritium | 1991 |
Positron emission tomography suggests that the rate of progression of idiopathic parkinsonism is slow.
Topics: Adult; Aged; Aging; Corpus Striatum; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors; Tomography, Emission-Computed | 1991 |
The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amphetamine; Animals; Corpus Striatum; Dopamine; In Vitro Techniques; Levodopa; Male; Rats; Selegiline | 1991 |
Age-related decrease in plasma growth hormone: response to growth hormone-releasing hormone, arginine, and L-dopa in obesity.
Topics: Adolescent; Adult; Aged; Aging; Arginine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Levodopa; Male; Middle Aged; Obesity | 1991 |
Early development of levodopa-induced dyskinesias and response fluctuations in young-onset Parkinson's disease.
Topics: Adult; Aging; Dyskinesia, Drug-Induced; Humans; Levodopa; Middle Aged; Movement; Parkinson Disease; Probability; Severity of Illness Index; Time Factors | 1991 |
Impaired secretion of growth hormone-releasing hormone, growth hormone and IGF-I in elderly men.
Topics: Adult; Aged; Aged, 80 and over; Aging; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Insulin-Like Growth Factor I; Levodopa; Male; Radioimmunoassay | 1991 |
L-dopa-induced air-stepping in decerebrate developing rats.
Topics: Aging; Animals; Animals, Newborn; Decerebrate State; Denervation; Electromyography; Levodopa; Motor Activity; Rats; Rats, Inbred Strains; Spinal Cord; Thorax | 1991 |
Changes in dopamine release in vitro from the corpus striatum of young versus aged rats as a function of infusion modes of L-dopa, potassium, and amphetamine.
Topics: Aging; Amphetamine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Infusions, Parenteral; Levodopa; Male; Potassium; Rats; Rats, Inbred Strains; Reference Values | 1991 |
[The sympathetic-adrenal system in mitral heart defects in patients of different ages studied by the use of a specific L-DOPA test].
Topics: Adrenal Glands; Adult; Aged; Aging; Dopamine; Epinephrine; Female; Heart Failure; Humans; Levodopa; Male; Middle Aged; Mitral Valve Insufficiency; Mitral Valve Stenosis; Norepinephrine; Sympathetic Nervous System; Vanilmandelic Acid | 1990 |
Vesicular and ganglionic norepinephrine in the rat: progressive increase with age.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Catecholamines; Chromatography, High Pressure Liquid; Cytoplasm; Dopamine; Ganglia, Sympathetic; Levodopa; Male; Norepinephrine; Osmolar Concentration; Rats; Rats, Inbred Strains; Synaptic Vesicles | 1990 |
Correction of arterial blood pressure in adult rats with inherited stress-induced arterial hypertension by enhancement of catecholamine metabolism in early postnatal period.
Topics: Aging; Animals; Animals, Newborn; Blood Pressure; Catecholamines; Hypertension; Levodopa; Male; Rats; Rats, Inbred Strains; Stress, Physiological | 1990 |
The effect of L-dopa upon in vitro dopamine release from the corpus striatum of young and old male rats.
Topics: Aging; Animals; Corpus Striatum; Dopamine; In Vitro Techniques; Levodopa; Male; Naloxone; Rats; Rats, Inbred Strains | 1989 |
Effect of mild postnatal hypoxia and L-dopa administration on dopamine concentration in striata of the newborn rat and long term sequelae on dopamine turnover.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Hypoxia, Brain; Levodopa; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Skin color, aging, and plasma L-dopa levels.
Topics: Adolescent; Adult; Aged; Aging; Black People; Humans; Levodopa; Middle Aged; Norepinephrine; Skin Pigmentation; White People | 1989 |
Effect of age at onset on progression and mortality in Parkinson's disease.
Topics: Aging; Athetosis; Chorea; Disability Evaluation; Humans; Levodopa; Middle Aged; Parkinson Disease | 1989 |
Recent developments in the treatment of Parkinson's disease.
Topics: Aged; Aging; Amantadine; Diagnosis, Differential; Drug Administration Schedule; Dyskinesia, Drug-Induced; Histamine H1 Antagonists; Humans; Levodopa; Parasympatholytics; Parkinson Disease; Physical Exertion | 1985 |
Neurotransmitter precursors and brain function.
Topics: Aged; Aging; Alzheimer Disease; Animals; Biological Transport; Brain; Diet; Humans; Learning; Levodopa; Memory; Neurotransmitter Agents; Parkinson Disease; Phosphatidylcholines; Serotonin; Sleep; Tryptophan | 1986 |
Effect of age on gastrointestinal and hepatic first-pass effects of levodopa in rats.
Topics: Administration, Oral; Aging; Animals; Biological Availability; Digestive System; Feces; Injections; Injections, Intravenous; Jejunum; Kinetics; Levodopa; Liver; Liver Circulation; Male; Portal Vein; Rats; Regional Blood Flow | 1987 |
Changes in the 5-HT-binding sites in the cerebral cortex, striatum and hypothalamus of rats during ageing and under the effect of dopaminergic agents.
Topics: Aging; Animals; Binding Sites; Cerebral Cortex; Corpus Striatum; Haloperidol; Hypothalamus; Levodopa; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin | 1987 |
Response to brief levodopa infusions in parkinsonian patients with and without motor fluctuations.
Topics: Aged; Aging; Humans; Levodopa; Middle Aged; Movement; Parkinson Disease; Time Factors | 1988 |
Neuropharmacological intervention with motor system aging.
Topics: Adult; Aged; Aging; Cognition; Gait; Humans; Levodopa; Middle Aged; Movement Disorders; Neuropharmacology; Neuropsychological Tests; Parkinson Disease; Posture; Reaction Time; Sympathomimetics | 1988 |
Human motor behavior and aging.
Topics: Aged; Aging; Brain; Extrapyramidal Tracts; Humans; Levodopa; Movement; Parkinson Disease; Reference Values | 1988 |
Pharmacology of mental aging and dementia disorders.
Topics: Acetylcholine; Aging; Alzheimer Disease; Dementia; Humans; Levodopa; Neuropeptides | 1987 |
[Critical review of geriatric preparations].
Topics: Aging; Androsterone; Free Radicals; Humans; Levodopa; Life Expectancy | 1987 |
Transient shortening of estrous cycles in aging C57BL/6J mice: effects of spontaneous pseudopregnancy, progesterone, L-dihydroxyphenylalanine, and hydergine.
Topics: Aging; Animals; Carbidopa; Dihydroergotoxine; Estrus; Female; Levodopa; Mice; Mice, Inbred C57BL; Ovulation; Progesterone; Pseudopregnancy; Silicone Elastomers; Time Factors | 1987 |
Age dependence in capacity-limited jejunal decarboxylation of levodopa in rats.
Topics: Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dopa Decarboxylase; Jejunum; Kinetics; Levodopa; Male; Mesenteric Veins; Rats; Rats, Inbred Strains | 1987 |
[Correction of arterial pressure in rats with hereditary hypertension by altering catecholamine metabolism in early ontogeny].
Topics: Aging; Animals; Blood Pressure; Catecholamines; Dopamine beta-Hydroxylase; Hypertension; Levodopa; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1987 |
[Regulation of isoproterenol-induced salivary gland hyperplasia in young and old mice by substances affecting the serotonin- and dopaminergic systems].
Topics: Aging; Animals; Female; Freund's Adjuvant; Hyperplasia; Isoproterenol; Levodopa; Mice; Mice, Inbred BALB C; Receptors, Dopamine; Receptors, Serotonin; Salivary Glands; Serotonin; Time Factors | 1986 |
Treatment with levodopa of motor dysfunction in the elderly.
Topics: Aged; Aging; Humans; Levodopa; Motor Neurons; Neuromuscular Diseases; Receptors, Dopamine | 1986 |
Growth hormone restores protein synthesis in skeletal muscle of old male rats.
Topics: Age Factors; Aging; Animals; Diaphragm; Growth Hormone; Levodopa; Male; Muscle Proteins; Muscles; Phenylalanine; Rats; Rats, Inbred Strains | 1985 |