levetiracetam and Sjogren-s-Syndrome

Sjogren's syndrome (SS), either primary or secondary, is rarely accompanied by CNS complications. We report the exceptional case of a patient with secondary SS, who presented orofacial dystonia as a consequence of her disease. Initial treatment with clonazepam and levetiracetam was unsuccessful. However, dystonia was dramatically improved by a treatment with corticosteroids. This case demonstrates that corticosteroids can be efficacious in the treatment of dystonia related to SS.

Topics: Adrenal Cortex Hormones; Brain; Clonazepam; Dystonia; Dystonic Disorders; Face; Female; Humans; Levetiracetam; Magnetic Resonance Imaging; Middle Aged; Piracetam; Remission Induction; Sjogren's Syndrome; Treatment Outcome