leuprolide has been researched along with Ileal-Diseases* in 2 studies
2 other study(ies) available for leuprolide and Ileal-Diseases
| Article | Year |
|---|---|
Intestinal endometriosis complicated by ileal perforation after initiation of gonadotropin-releasing hormone agonist therapy.
To report a rare complication of GnRH agonist therapy for intestinal endometriosis.. Case report.. University hospital.. A 45-year-old nulliparous Japanese woman with catamenial digestive symptoms.. GnRH agonist therapy.. Acute abdomenal crisis with free air in the abdominal X-ray.. An emergency laparotomy showed both an ileal constriction and perforation. An ileocecal enterectomy with an end-to-end anastomosis was performed. A pathological examination of the ileum revealed ileal endometriosis.. Flare-up of intestinal endometriosis induced by GnRH agonist has the potential to lead to intestinal perforation. Careful diagnosis and treatment are necessary for cyclic and periodic gastrointestinal manifestation. Topics: Abdomen, Acute; Endometriosis; Female; Gonadotropin-Releasing Hormone; Humans; Ileal Diseases; Intestinal Perforation; Leuprolide; Middle Aged | 2007 |
Flare-up of endometriosis induced by gonadotropin-releasing hormone agonist leading to bowel obstruction.
To report a case of intestinal obstruction that developed shortly after preoperative administration of a GnRH analogue (GnRH-a) that caused flare-up and rapid progression of enteric endometriosis.. Case report.. University tertiary reproductive endocrinology practice.. A 34-year-old nulligravid female with progressive severe symptomatic endometriosis.. Planned preoperative administration of GnRH-a for 3 months followed by extirpative surgery and hormone replacement therapy. Instead, total abdominal hysterectomy, bilateral salpingoophorectomy, resection of the obstructed ileocecal junction, and side-to-side ileo-ascending enterocolostomy was performed.. Preoperative GnRH-a administered in the midfollicular phase resulted in flare-up of preexisting ileocecal endometriosis that rapidly progressed, resulting in partial small bowel obstruction.. Gonadotropin-releasing hormone agonist should be used with caution when there is known or suspected enteric endometriosis. Consideration should be given to blocking the agonistic effect of GnRH-a in this setting by the prior or concomitant use of progestins or danazol. Topics: Adult; Endometriosis; Female; Humans; Hysterectomy; Ileal Diseases; Ileocecal Valve; Intestinal Obstruction; Leuprolide | 1995 |