leuprolide and Cicatrix

Abdominal wall endometriosis usually occurs in the surgical scar of previous cesarean sections. This condition often presents as a mass with cyclical pain and swelling. Two cases of abdominal scar endometriosis are reported. The definitive diagnosis was established by pathologic analysis. Both patients were premenopausal with no history of endometriosis. Pelvic endometriosis was not detected in the patient undergone laparotomy. The management consisted in perform and adequate excision to prevent recurrence. The utility of drug therapy is evaluated.

Topics: Abdominal Muscles; Adult; Antineoplastic Agents, Hormonal; Cesarean Section; Cicatrix; Danazol; Endometriosis; Estrogen Antagonists; Female; Humans; Leuprolide; Muscular Diseases; Postoperative Care; Time Factors

Progestin or estrogen-progestin combination therapy has not proven useful in the treatment of endometriosis of the abdominal scar after cesarean delivery. We report our experience in managing this condition with a gonadotropin agonist.. A 22-year-old black woman with a history of two previous cesareans developed endometriosis of the abdominal scar. The extent of the lesion was estimated by computed tomographic (CT) scan, and a 6-month preoperative course of leuprolide acetate was administered. The patient exhibited prompt symptomatic response to the gonadotropin agonist, but the physical examination and CT scan findings were unchanged. Pathologic examination after surgical removal of the lesion confirmed the clinical diagnosis.. Leuprolide acetate administered to a patient with cesarean scar endometriosis was associated with an improvement in symptoms, but there was no change in lesion size.

Topics: Adult; Cesarean Section; Cicatrix; Endometriosis; Female; Humans; Leuprolide; Postoperative Complications; Pregnancy; Tomography, X-Ray Computed