leupeptin has been researched along with Aging in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brunk, UT; Dalen, H; Stroikin, Y; Terman, A | 1 |
| Agarwal, S; Sohal, RS | 1 |
| Ivy, GO; Kanai, S; Kitani, K; Ohta, M; Roopsingh, R; Sato, Y | 1 |
| Gao, CL; Katz, ML; Rice, LM | 1 |
| Ivy, GO | 1 |
| Ivy, GO; Kanai, S; Kitani, K; Ohta, M; Otsubo, K; Sato, Y | 1 |
| Ivy, GO; Kanai, S; Kitani, K; Kobayashi, M; Ohta, M; Sato, Y; Smith, G | 1 |
| Ivy, GO; Kanai, S; Kitani, K; Nokubo, M; Ohta, M; Otsubo, K; Sato, Y | 1 |
| Danzo, BJ | 1 |
| Ikeno, K; Ikeno, T; Ishiguro, I; Kuzuya, H | 1 |
10 other study(ies) available for leupeptin and Aging
| Article | Year |
|---|---|
Testing the "garbage" accumulation theory of ageing: mitotic activity protects cells from death induced by inhibition of autophagy.
Topics: Adenine; Aging; Astrocytes; Autophagy; Cell Line; Cell Survival; Cellular Senescence; Cysteine Proteinase Inhibitors; Fibroblasts; Humans; Leupeptins; Mitosis; Phosphoinositide-3 Kinase Inhibitors | 2005 |
Aging and proteolysis of oxidized proteins.
Topics: Aging; Animals; Aprotinin; Endopeptidases; Enzyme Stability; Hot Temperature; Houseflies; Hydrogen-Ion Concentration; Leupeptins; Male; Oxidation-Reduction; Protease Inhibitors; Proteins; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine | 1994 |
Leupeptin causes an accumulation of lipofuscin-like substances and other signs of aging in kidneys of young rats: further evidence for the protease inhibitor model of aging.
Topics: Aging; Animals; Kidney; Leupeptins; Lipofuscin; Male; Microscopy, Electron; Models, Biological; Protease Inhibitors; Rats; Rats, Inbred F344 | 1996 |
Reversible accumulation of lipofuscin-like inclusions in the retinal pigment epithelium.
Topics: Aging; Animals; Eye Proteins; Inclusion Bodies; Injections; Leupeptins; Lipofuscin; Male; Microscopy, Fluorescence; Pigment Epithelium of Eye; Rats; Rats, Inbred F344; Vitreous Body | 1999 |
Protease inhibition causes some manifestations of aging and Alzheimer's disease in rodent and primate brain.
Topics: Aging; Alzheimer Disease; Animals; Brain; Dolichols; Endopeptidases; Humans; Immunologic Techniques; Intermediate Filaments; Leucine; Leupeptins; Lipofuscin; Macaca fascicularis; Male; Protease Inhibitors; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Ubiquitins | 1992 |
Leupeptin causes an accumulation of lipofuscin-like substances in liver cells of young rats.
Topics: Aging; Animals; Ceroid; Histocytochemistry; Leupeptins; Lipofuscin; Liver; Male; Microscopy, Fluorescence; Rats; Rats, Inbred F344 | 1991 |
Lipofuscin-like substances accumulate rapidly in brain, retina and internal organs with cysteine protease inhibition.
Topics: Aging; Animals; Brain; Cysteine Proteinase Inhibitors; Dogs; Leupeptins; Lipofuscin; Lysosomes; Mice; Mice, Inbred C57BL; Microscopy, Electron; Rats; Rats, Inbred F344; Rats, Inbred Strains; Retina; Viscera | 1989 |
Morphological, physiological and biochemical alterations in livers of rodents induced by protease inhibitors: a comparison with old livers.
Topics: Aging; Animals; Biological Transport; Dolichols; Leucine; Leupeptins; Liver; Male; Mice; Mice, Inbred C57BL; Ouabain; Protease Inhibitors; Rats; Rats, Inbred F344; Rats, Inbred Strains; Sulfobromophthalein | 1989 |
A protease acting on the estrogen receptor may modify its action in the adult rabbit epididymis.
Topics: Aging; Animals; Cell Nucleus; Centrifugation, Density Gradient; Epididymis; Estradiol; Estrogens; Genitalia, Male; In Vitro Techniques; Leupeptins; Male; Orchiectomy; Peptide Hydrolases; Rabbits; Receptors, Estrogen | 1986 |
Effect of leupeptin, a protease inhibitor, on dopa decarboxylase and protease activities in homogenates of submandibular salivary glands from young rats.
Topics: Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dopa Decarboxylase; Female; Leupeptins; Male; Oligopeptides; Peptide Hydrolases; Rats; Rats, Inbred Strains; Submandibular Gland | 1986 |