leukotriene-e4 and Mucocutaneous-Lymph-Node-Syndrome

leukotriene-e4 has been researched along with Mucocutaneous-Lymph-Node-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for leukotriene-e4 and Mucocutaneous-Lymph-Node-Syndrome

ArticleYear
Increased generation of cysteinyl leukotrienes in Kawasaki disease.
    Archives of disease in childhood, 1995, Volume: 72, Issue:6

    Endogenous cysteinyl leukotriene synthesis was assessed in 10 patients with Kawasaki disease and 10 healthy controls by measuring excretion of leukotriene E4 (LTE4) in urine. LTE4 was increased more than fivefold in patients with Kawasaki disease compared with controls (median (range) 55.3 (31.8-120.6) v 10.2 (7.1-14.9) nmol/mol creatinine); this suggests that cysteinyl leukotrienes are involved in the pathophysiology of Kawasaki disease. Leukotriene synthetase inhibition or receptor antagonism may therefore offer a new potential therapeutic approach in children with this disease.

    Topics: Child, Preschool; Chromatography, Gas; Chromatography, High Pressure Liquid; Female; Humans; Infant; Leukotriene E4; Male; Mass Spectrometry; Mucocutaneous Lymph Node Syndrome; Reference Values

1995