leukotriene-b4 and Meningitis--Cryptococcal

leukotriene-b4 has been researched along with Meningitis--Cryptococcal* in 2 studies

Other Studies

2 other study(ies) available for leukotriene-b4 and Meningitis--Cryptococcal

Article	Year
[Leukotriene B4 level in cerebrospinal fluid of patients with tuberculosis meningitis and clinical significance]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2015, Volume: 31, Issue:8 To investigate the level of leukotriene B4 (LTB4) in the cerebrospinal fluid (CSF) of patients with tuberculosis meningitis (TBM) and analyze the relationships of LTB4 level with cytological parameters and disease severity.. By ELISA, LTB4 levels were measured in the CSF of the patients with TBM (diagnosed by modified Ziehl-Neelsen staining), cryptococcal meningitis (CM), central nervous system leukemia (CNSL) or non-inflammatory neurological disease (NIND). CSF cytological testing was performed in TBM patients. Disease severity was evaluated by modified Rankin scale (mRS). LTB4 levels were compared between different disease groups, and the relationships of LTB4 level with white blood cell (WBC) counts, neutrophil counts and disease severity were analyzed statistically.. Compared with CM, CNSL or NIND patients, CSF LTB4 level in TBM patients was remarkably higher. CSF LTB4 level in TBM patients was related to neutrophil counts and neutrophil percentages, but not related to WBC counts. No simple linear correlation was found between CSF LTB4 level and disease severity.. CSF LTB4 level in TBM patients can be used as a predictor of inflammation degree, but its relationship with disease severity and prognosis need further exploration. Topics: Adolescent; Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Child; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leukemia; Leukotriene B4; Male; Meningitis, Cryptococcal; Middle Aged; Nervous System Diseases; Prognosis; Severity of Illness Index; Tuberculosis, Meningeal; Young Adult	2015
Low levels of LTB4 in cerebrospinal fluid of AIDS patients with cryptococcal meningitis. Journal of clinical & laboratory immunology, 1995, Volume: 47, Issue:1 In this study we evaluated the release of leukotriene B4 (LTB4) in the cerebrospinal fluid (CSF) of 12 patients with Acquired Immunodeficiency Syndrome (AIDS), which disease was complicated by Cryptococcal Meninigitis and in CSF of 12 control subjects with inflammatory and degenerative pathologies of the Central Nervous System (CNS). We obtained low levels of LTB4 in all the AIDS patients (mean 60.5 pg/ml), while the HIV negative subjects with degenerative and inflammatory pathologies of CNS showed a mean of 91.5 pg/ml. The finding of low levels of this inflammatory reaction mediator agrees with the limited clinical symptoms of cryptococcal meningoencephalitis in patients affected by AIDS. Topics: Acquired Immunodeficiency Syndrome; Adult; Binding, Competitive; Female; Humans; Leukotriene B4; Male; Meningitis, Cryptococcal; Middle Aged; Radioimmunoassay	1995

Article

Year

[Leukotriene B4 level in cerebrospinal fluid of patients with tuberculosis meningitis and clinical significance].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2015, Volume: 31, Issue:8

To investigate the level of leukotriene B4 (LTB4) in the cerebrospinal fluid (CSF) of patients with tuberculosis meningitis (TBM) and analyze the relationships of LTB4 level with cytological parameters and disease severity.. By ELISA, LTB4 levels were measured in the CSF of the patients with TBM (diagnosed by modified Ziehl-Neelsen staining), cryptococcal meningitis (CM), central nervous system leukemia (CNSL) or non-inflammatory neurological disease (NIND). CSF cytological testing was performed in TBM patients. Disease severity was evaluated by modified Rankin scale (mRS). LTB4 levels were compared between different disease groups, and the relationships of LTB4 level with white blood cell (WBC) counts, neutrophil counts and disease severity were analyzed statistically.. Compared with CM, CNSL or NIND patients, CSF LTB4 level in TBM patients was remarkably higher. CSF LTB4 level in TBM patients was related to neutrophil counts and neutrophil percentages, but not related to WBC counts. No simple linear correlation was found between CSF LTB4 level and disease severity.. CSF LTB4 level in TBM patients can be used as a predictor of inflammation degree, but its relationship with disease severity and prognosis need further exploration.

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Child; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leukemia; Leukotriene B4; Male; Meningitis, Cryptococcal; Middle Aged; Nervous System Diseases; Prognosis; Severity of Illness Index; Tuberculosis, Meningeal; Young Adult

2015

Low levels of LTB4 in cerebrospinal fluid of AIDS patients with cryptococcal meningitis.

Journal of clinical & laboratory immunology, 1995, Volume: 47, Issue:1

In this study we evaluated the release of leukotriene B4 (LTB4) in the cerebrospinal fluid (CSF) of 12 patients with Acquired Immunodeficiency Syndrome (AIDS), which disease was complicated by Cryptococcal Meninigitis and in CSF of 12 control subjects with inflammatory and degenerative pathologies of the Central Nervous System (CNS). We obtained low levels of LTB4 in all the AIDS patients (mean 60.5 pg/ml), while the HIV negative subjects with degenerative and inflammatory pathologies of CNS showed a mean of 91.5 pg/ml. The finding of low levels of this inflammatory reaction mediator agrees with the limited clinical symptoms of cryptococcal meningoencephalitis in patients affected by AIDS.

Topics: Acquired Immunodeficiency Syndrome; Adult; Binding, Competitive; Female; Humans; Leukotriene B4; Male; Meningitis, Cryptococcal; Middle Aged; Radioimmunoassay

1995