leukotriene-b4 and Endophthalmitis

leukotriene-b4 has been researched along with Endophthalmitis* in 2 studies

Other Studies

2 other study(ies) available for leukotriene-b4 and Endophthalmitis

Article	Year
Inflammatory mediators in postoperative aphakic and pseudophakic baboon eyes. Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:12 We measured prostaglandin E2 and leukotriene B4 in the aqueous humor of baboon eyes, 1 or 8 days after phacoemulsification, with or without posterior chamber lens implantation. We also evaluated the effects of steroid eye drops and cyclooxygenase inhibitor eye drops on the synthesis of these mediators of inflammation. Eyes that had undergone phacoemulsification showed significant elevation of prostaglandin E2 at both postoperative periods compared with normal, phakic control eyes. The level of prostaglandin E2 was significantly (P less than .05) higher in eyes with posterior chamber lens implantation than in those without it, and was significantly (P less than .05) higher on the eighth than on the first postoperative day. The amount of leukotriene B4 was below the detection limit, except in the few eyes in which complications developed. Cyclooxygenase inhibitor eye drops significantly reduced the amount of prostaglandin E2 on both postoperative days, while steroid eye drops had no such effect. Topics: Animals; Aphakia, Postcataract; Aqueous Humor; Cataract; Endophthalmitis; Eye; Eye Proteins; Lenses, Intraocular; Leukocytes; Leukotriene B4; Papio; Prostaglandins E	1990
Inflammatory responses to intraocularly injected interleukin 1. Current eye research, 1987, Volume: 6, Issue:7 Intraocular injection of highly purified human interleukin 1 into the anterior chamber of the rabbit eye resulted in the accumulation of inflammatory cells. Peak cellular infiltration occurred at 4hr and cells were still present at 24h. Examination of ocular blood vessels in IL-1-injected eyes revealed no abnormalities. IL-1 had no effect on the protein content of the aqueous humour confirming that this monokine has no direct action on the blood-aqueous barrier. Comparison of the potency of IL-1 as a chemoattractant with the 5-lipoxygenase product, leukotriene B4 demonstrated that the former agent was more active by several orders of magnitude. Topics: Animals; Anterior Chamber; Dinoprostone; Endophthalmitis; Eye; Injections; Interleukin-1; Leukotriene B4; Lipopolysaccharides; Male; Prostaglandins E; Rabbits; Vasodilation	1987

Article

Year

Inflammatory mediators in postoperative aphakic and pseudophakic baboon eyes.

Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:12

We measured prostaglandin E2 and leukotriene B4 in the aqueous humor of baboon eyes, 1 or 8 days after phacoemulsification, with or without posterior chamber lens implantation. We also evaluated the effects of steroid eye drops and cyclooxygenase inhibitor eye drops on the synthesis of these mediators of inflammation. Eyes that had undergone phacoemulsification showed significant elevation of prostaglandin E2 at both postoperative periods compared with normal, phakic control eyes. The level of prostaglandin E2 was significantly (P less than .05) higher in eyes with posterior chamber lens implantation than in those without it, and was significantly (P less than .05) higher on the eighth than on the first postoperative day. The amount of leukotriene B4 was below the detection limit, except in the few eyes in which complications developed. Cyclooxygenase inhibitor eye drops significantly reduced the amount of prostaglandin E2 on both postoperative days, while steroid eye drops had no such effect.

Topics: Animals; Aphakia, Postcataract; Aqueous Humor; Cataract; Endophthalmitis; Eye; Eye Proteins; Lenses, Intraocular; Leukocytes; Leukotriene B4; Papio; Prostaglandins E

1990

Inflammatory responses to intraocularly injected interleukin 1.

Current eye research, 1987, Volume: 6, Issue:7

Intraocular injection of highly purified human interleukin 1 into the anterior chamber of the rabbit eye resulted in the accumulation of inflammatory cells. Peak cellular infiltration occurred at 4hr and cells were still present at 24h. Examination of ocular blood vessels in IL-1-injected eyes revealed no abnormalities. IL-1 had no effect on the protein content of the aqueous humour confirming that this monokine has no direct action on the blood-aqueous barrier. Comparison of the potency of IL-1 as a chemoattractant with the 5-lipoxygenase product, leukotriene B4 demonstrated that the former agent was more active by several orders of magnitude.

Topics: Animals; Anterior Chamber; Dinoprostone; Endophthalmitis; Eye; Injections; Interleukin-1; Leukotriene B4; Lipopolysaccharides; Male; Prostaglandins E; Rabbits; Vasodilation

1987