leukotriene-b4 and Appendicitis

leukotriene-b4 has been researched along with Appendicitis* in 2 studies

Trials

1 trial(s) available for leukotriene-b4 and Appendicitis

Article	Year
Urine leukotriene B4 in familial Mediterranean fever and other forms of right lower abdominal pain. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:7 Acute right lower abdominal pain may present a diagnostic dilemma. Leukotrienes have been found to be elevated in familial Mediterranean fever (FMF), a disease manifesting with recurrent episodes of "acute abdomen.". To determine whether urine leukotriene B4 (LTB4) may differentiate between an FMF attack and some other forms of acute right lower abdominal pain.. The LTB4 level was determined, using a commercial enzyme-linked immunosorbent assay (ELISA), in urine samples obtained from 36 patients with acute (< 24 hours) right lower abdominal pain presenting to the emergency department, and from 18 healthy volunteers.. Compared with the healthy control subjects, LTB4 was significantly higher in those who had FMF (12 patients, p < 0.03). In other forms of acute right lower abdominal pain, including appendicitis (eight patients), urologic disorders (eight patients), and nonspecific abdominal pain (eight patients), intermediate levels of LTB4 were observed, not significantly different from those of either FMF patients or healthy control subjects.. In the samples tested, urine LTB4 levels were not instrumental in differentiating FMF from other acute right lower abdominal pain. Topics: Abdominal Pain; Acute Disease; Adult; Appendicitis; Diagnosis, Differential; Familial Mediterranean Fever; Female; Humans; Leukotriene B4; Male; Middle Aged; Reference Values; Sensitivity and Specificity	2005

Article

Year

Urine leukotriene B4 in familial Mediterranean fever and other forms of right lower abdominal pain.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:7

Acute right lower abdominal pain may present a diagnostic dilemma. Leukotrienes have been found to be elevated in familial Mediterranean fever (FMF), a disease manifesting with recurrent episodes of "acute abdomen.". To determine whether urine leukotriene B4 (LTB4) may differentiate between an FMF attack and some other forms of acute right lower abdominal pain.. The LTB4 level was determined, using a commercial enzyme-linked immunosorbent assay (ELISA), in urine samples obtained from 36 patients with acute (< 24 hours) right lower abdominal pain presenting to the emergency department, and from 18 healthy volunteers.. Compared with the healthy control subjects, LTB4 was significantly higher in those who had FMF (12 patients, p < 0.03). In other forms of acute right lower abdominal pain, including appendicitis (eight patients), urologic disorders (eight patients), and nonspecific abdominal pain (eight patients), intermediate levels of LTB4 were observed, not significantly different from those of either FMF patients or healthy control subjects.. In the samples tested, urine LTB4 levels were not instrumental in differentiating FMF from other acute right lower abdominal pain.

Topics: Abdominal Pain; Acute Disease; Adult; Appendicitis; Diagnosis, Differential; Familial Mediterranean Fever; Female; Humans; Leukotriene B4; Male; Middle Aged; Reference Values; Sensitivity and Specificity

2005

Other Studies

1 other study(ies) available for leukotriene-b4 and Appendicitis

Article	Year
Leukotriene B4 and 20-OH-LTB4 in purulent peritoneal exudates demonstrated by GC-MS. Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:1 Inflammatory peritoneal exudates from 11 patients with purulent peritonitis or non-perforative appendicitis were analyzed by gas chromatography mass spectrometry (GC-MS) for their content of 5S, 12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid (LTB4) and its omega-oxidized catabolite, 5S,12R,20-trihydroxy-6,8,10,14-eicosatetraenoic acid (20-OH-LTB4). Eleven samples of peritoneal exudates were examined. LTB4 and 20-OH-LTB4 were demonstrated only in the samples from patients with purulent peritonitis. LTB4 was detected in 4 samples, and 20-OH-LTB4 was detected in 6 samples by GC-MS with selected ion monitoring. In addition, a nearly full spectrum corresponding to that of synthetic 20-OH-LTB4 was obtained with 3 samples. Neither LTB4 nor 20-OH-LTB4 were detected in samples from patients with non-perforative appendicitis. LTB4 or 20-OH-LTB4 may be related to the pathophysiological mechanism of purulent inflammations. Topics: Appendicitis; Ascitic Fluid; Gas Chromatography-Mass Spectrometry; Humans; Inflammation; Leukotriene B4; Peritonitis	1986

Article

Year

Leukotriene B4 and 20-OH-LTB4 in purulent peritoneal exudates demonstrated by GC-MS.

Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:1

Inflammatory peritoneal exudates from 11 patients with purulent peritonitis or non-perforative appendicitis were analyzed by gas chromatography mass spectrometry (GC-MS) for their content of 5S, 12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid (LTB4) and its omega-oxidized catabolite, 5S,12R,20-trihydroxy-6,8,10,14-eicosatetraenoic acid (20-OH-LTB4). Eleven samples of peritoneal exudates were examined. LTB4 and 20-OH-LTB4 were demonstrated only in the samples from patients with purulent peritonitis. LTB4 was detected in 4 samples, and 20-OH-LTB4 was detected in 6 samples by GC-MS with selected ion monitoring. In addition, a nearly full spectrum corresponding to that of synthetic 20-OH-LTB4 was obtained with 3 samples. Neither LTB4 nor 20-OH-LTB4 were detected in samples from patients with non-perforative appendicitis. LTB4 or 20-OH-LTB4 may be related to the pathophysiological mechanism of purulent inflammations.

Topics: Appendicitis; Ascitic Fluid; Gas Chromatography-Mass Spectrometry; Humans; Inflammation; Leukotriene B4; Peritonitis

1986