leukotoxin has been researched along with Enteritis* in 1 studies
1 other study(ies) available for leukotoxin and Enteritis
Article | Year |
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Partial characterization of the leukotoxin of Pasteurella haemolytica-like bacteria isolated from swine enteritis.
Pasteurella haemolytica-like (PHL) strains isolated from diarrheic pigs are known to produce a leukotoxin that is lethal to ruminant leukocytes. In the present study, 12 PHL strains were screened for leukotoxin production using a tetrazolium dye-reduction assay. Sterile culture supernatant from strain 6213A, the maximum leukotoxin producer, was used as the crude leukotoxin for characterization studies. The leukotoxin was inactivated by heat at 60 degrees C and by trypsin, protease, and amylase. Toxicity was retained over a pH range of 3.0-11.0. The leukotoxin was lethal to polymorphoneutrophils (PMNs) of cattle, sheep, goat, and swine. Chromosomal DNA of all 12 PHL strains hybridized with a 3.9 kb Pasteurella haemolytica A1 leukotoxin probe, indicating similarities between the leukotoxin genes of P. haemolytica and PHL strains. Topics: Animals; Bacterial Toxins; Cattle; Diarrhea; DNA, Bacterial; Enteritis; Exotoxins; In Vitro Techniques; Kinetics; Mannheimia haemolytica; Neutrophils; Pasteurella Infections; Species Specificity; Swine; Swine Diseases | 1995 |