Compounds > leucine

leucine and Urinary Bladder Neoplasms

leucine has been researched along with Urinary Bladder Neoplasms in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199017 (48.57)18.7374
1990's8 (22.86)18.2507
2000's4 (11.43)29.6817
2010's5 (14.29)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
Cai, X; Chen, Y; Ying, X; Zhou, B1
Cui, M; Guo, F; Liu, S; Liu, W; Liu, Y; Wang, X; Wu, R; Zhang, L; Zhang, Y1
Kakehashi, A; Takeshita, M; Wanibuchi, H; Wei, M; Xie, XL; Yamano, S; Yunoki, T1
Fischer, JW; Freudenberger, T; Kretschmer, I; Nagy, N; Niedworok, C; Reis, H; Röck, K; Rübben, H; Szarvas, T; Vom Dorp, F1
Abbar, M; Al Bouzidi, A; Ameur, A; Ameziane El Hassani, R; Attaleb, M; Dakka, N; El Mzibri, M; Hadami, K1
Kakehashi, A; Kato, M; Wanibuchi, H; Wei, M; Xie, XL; Yamano, S; Yunoki, T1
Anzai, N; Babu, E; Chairoungdua, A; Choi, HW; Endou, H; Iribe, Y; Kanai, Y; Kim, DK; Tachampa, K; Tangtrongsup, S1
Habuchi, T; Ichimura, Y; Kato, T; Nishiyama, H; Ogawa, O; Oyama, C; Sato, K; Tsuchiya, N; Wang, L1
Amorós, A; Carrato, A; Hernández, S; Kogevinas, M; Lloreta, J; López-Knowles, E; Malats, N; Real, FX; Serra, C; Tardón, A1
Blomgren, H; Edsmyr, F; Esposti, PL; Näslund, I1
Hakomori, S; Hellström, I; Hellström, KE; Kohwi, Y1
Honma, Y; Kakizoe, T; Niijima, T; Nishio, Y; Sugimura, T1
Kato, T; Nemoto, R1
Aaronson, SA; Dunn, CY; Reddy, EP; Rhim, JS; Srivastava, SK; Yuasa, Y1
Akaza, H; Kobayashi, K; Niijima, T; Umeda, T; Yokoyama, H1
Jacob, HS; Kay, NE; LeMarbre, P; Rinehart, JJ; Vesella, R1
Kobayashi, Y; Watanabe, N1
Boyer, MJ; Firestone, RA; Horn, I; Steele-Norwood, D; Tannock, IF1
Koshida, K; Kunimi, K; Uchibayashi, T; Yamamoto, H1
Andreesen, R; Konur, A; Krause, SW; Kreutz, M; Rehli, M1
Huang, JK; Jan, CR; Yu, CC1
Mizutani, Y; Nio, Y; Yoshida, O1
Droller, MJ; Hodge, DE; Liu, BC; Redwood, SM; Weiss, RE1
Asakawa, M; Horii, A; Kyo, M; Maekawa, M; Yasumoto, R1
Blomgren, H; Esposti, PL; Johansen, L; Lemming, O; Näslund, I1
Aso, Y; Kitagawa, M; Suzuki, K; Tajima, A; Ushiyama, T1
Aoyama, T; Furuya, S; Honma, A; Kato, S; Kumamoto, Y; Takatsuka, K; Tamiya, T; Tanda, H; Tsukamoto, T; Yokoyama, E1
Aaskoven, O; Blomgren, H; Esposti, PL; Johansen, L; Näslund, I1
Hosaka, M; Kubota, Y; Miura, T; Sakuramoto, T1
Lehman, TA; Schut, HA; Shivapurkar, N; Stoner, GD1
Blomgren, H; Edsmyr, F; von Stedingk, LV; Wasserman, J1
Fukushima, S; Kakizoe, T; Nishio, Y; Ohtani, M; Sato, S; Sugimura, T1
Hirokawa, I; Ichikawa, T; Ishihara, Y1
Amaral, L; Pai, SH; Werthamer, S; Zak, FG1
Hahn, K; Jesdinsky, HJ; Ladner, HA1

Trials

6 trial(s) available for leucine and Urinary Bladder Neoplasms

ArticleYear
Immunological and haematological monitoring in bladder cancer patients receiving adjuvant bestatin treatment following radiation therapy. A prospective randomized trial.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1984, Volume: 38, Issue:3

    Topics: Adjuvants, Immunologic; Aged; Blood Cell Count; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Leucine; Male; Middle Aged; Time Factors; Urinary Bladder Neoplasms

1984
Adjuvant therapy with 5-fluoro-1-(2-tetrahydrofuryl)-2,4 (1H,3H)-pyrimidinedione (UFT) and Bestatin in patients with transitional cell carcinoma of the bladder--comparison between UFT therapy alone and UFT therapy in combination with Bestatin.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:8

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Female; Humans; Isomerism; Leucine; Male; Middle Aged; Prospective Studies; Tegafur; Urinary Bladder Neoplasms

1995
Adjuvant bestatin (Ubenimex) treatment following full-dose local irradiation for bladder carcinoma.
    Acta oncologica (Stockholm, Sweden), 1990, Volume: 29, Issue:6

    Topics: Adjuvants, Immunologic; Aged; Antibiotics, Antineoplastic; Carcinoma, Transitional Cell; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Leucine; Male; Middle Aged; Survival Analysis; Urinary Bladder Neoplasms

1990
[Clinical research on prevention of recurrence of superficial bladder cancer--comparative study on clinical efficacy of bleomycin intravesical instillation and bestatin].
    Hinyokika kiyo. Acta urologica Japonica, 1985, Volume: 31, Issue:10

    Topics: Adolescent; Adult; Aged; Animals; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Transitional Cell; Chemotherapy, Cancer, Regional Perfusion; Child; Child, Preschool; Dogs; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Leucine; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Urinary Bladder Neoplasms

1985
Adjuvant Bestatin immunotherapy in patients with transitional cell carcinoma of the bladder. Clinical results of a randomized trial.
    Cancer immunology, immunotherapy : CII, 1987, Volume: 25, Issue:1

    Topics: Adjuvants, Immunologic; Aged; Carcinoma, Transitional Cell; Combined Modality Therapy; Female; Humans; Leucine; Male; Prospective Studies; Random Allocation; Urinary Bladder Neoplasms

1987
Bestatin treatment enhances the recovery of radiation induced impairments of the immunological reactivity of the blood lymphocyte population in bladder cancer patients.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1986, Volume: 40, Issue:2

    Topics: Adjuvants, Immunologic; Combined Modality Therapy; Humans; Immunoglobulins; In Vitro Techniques; Leucine; Leukocyte Count; Lymphocyte Activation; Lymphocytes; Prospective Studies; Random Allocation; Urinary Bladder Neoplasms

1986

Other Studies

29 other study(ies) available for leucine and Urinary Bladder Neoplasms

ArticleYear
A Comprehensive Pan-Cancer Analysis of the Tumorigenic Effect of Leucine-Zipper-Like Transcription Regulator (LZTR1) in Human Cancer.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Carcinogenesis; Carcinoma, Transitional Cell; Endothelial Cells; Humans; Leucine; Male; Transcription Factors; Urinary Bladder Neoplasms

2022
Ubenimex, an APN inhibitor, could serve as an anti‑tumor drug in RT112 and 5637 cells by operating in an Akt‑associated manner.
    Molecular medicine reports, 2018, Volume: 17, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; CD13 Antigens; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Leucine; Proto-Oncogene Proteins c-akt; Signal Transduction; Urinary Bladder Neoplasms

2018
L-Leucine and L-isoleucine enhance growth of BBN-induced urothelial tumors in the rat bladder by modulating expression of amino acid transporters and tumorigenesis-associated genes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59

    Topics: Amino Acid Transport System y+; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Amino Acids, Branched-Chain; Animals; Carcinogenesis; Dietary Supplements; Fusion Regulatory Protein 1, Heavy Chain; Fusion Regulatory Protein 1, Light Chains; Gene Expression Regulation, Neoplastic; Hyperplasia; Isoleucine; Large Neutral Amino Acid-Transporter 1; Leucine; Male; Neoplasm Proteins; Random Allocation; Rats; Rats, Inbred F344; Tumor Burden; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium

2013
Inhibitory role of the small leucine-rich proteoglycan biglycan in bladder cancer.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Biglycan; Gene Expression Regulation, Neoplastic; Humans; Indoles; Leucine; Male; Mice; Mice, Nude; Niacinamide; Phenylurea Compounds; Pyrroles; RNA, Messenger; Sorafenib; Sunitinib; Urinary Bladder Neoplasms

2013
Association between GPX1 Pro189Leu polymorphism and the occurrence of bladder cancer in Morocco.
    Cellular and molecular biology (Noisy-le-Grand, France), 2016, Dec-30, Volume: 62, Issue:14

    Topics: Adult; Aged; Alleles; Base Sequence; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Leucine; Male; Middle Aged; Morocco; Polymorphism, Genetic; Proline; Risk Factors; Urinary Bladder Neoplasms

2016
Long-term treatment with L-isoleucine or L-leucine in AIN-93G diet has promoting effects on rat bladder carcinogenesis.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:11

    Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Diet; Dietary Supplements; Hydrogen-Ion Concentration; Isoleucine; Leucine; Male; Papilloma; Rats; Rats, Inbred F344; Urinalysis; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium

2012
Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells.
    Biochimica et biophysica acta, 2002, Sep-20, Volume: 1565, Issue:1

    Topics: Amino Acids, Cyclic; Biological Transport; Blotting, Northern; Carbon Radioisotopes; Cell Membrane; Endocytosis; Fluorescent Antibody Technique; Fusion Regulatory Protein 1, Heavy Chain; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Microscopy, Confocal; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2002
Increased risk of bladder cancer associated with a glutathione peroxidase 1 codon 198 variant.
    The Journal of urology, 2004, Volume: 172, Issue:2

    Topics: Aged; Alanine; Asian People; Carcinoma, Transitional Cell; Female; Genetic Predisposition to Disease; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Leucine; Logistic Models; Male; Middle Aged; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Superoxide Dismutase; Urinary Bladder Neoplasms; Valine

2004
Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Aug-01, Volume: 24, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Cysteine; Female; Glutamic Acid; Glycine; Humans; Leucine; Male; Middle Aged; Multivariate Analysis; Mutation; Phenylalanine; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Receptor, Fibroblast Growth Factor, Type 3; Sequence Analysis, DNA; Serine; Tyrosine; Urinary Bladder Neoplasms

2006
Amphipathic lipid-bound protein antigens in mouse bladder carcinomas detected by a monoclonal antibody.
    Biochemistry, 1984, Dec-04, Volume: 23, Issue:25

    Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens, Neoplasm; Chloroform; Chromatography; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Immunosorbent Techniques; Leucine; Mice; Mice, Inbred BALB C; Palmitic Acid; Palmitic Acids; Proteins; Rats; Solubility; Urinary Bladder Neoplasms; Water

1984
L-Isoleucine and L-leucine are promoters of bladder cancer in rats.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cells, Cultured; Isoleucine; Leucine; Male; Rats; Urinary Bladder Neoplasms

1983
Rapid assay system for cytotoxicity tests using 14C-leucine incorporation into tumor cells.
    The Tohoku journal of experimental medicine, 1980, Volume: 131, Issue:3

    Topics: Antineoplastic Agents; Carbon Radioisotopes; Carcinoma, Transitional Cell; Cell Line; Cell Survival; Cytological Techniques; Hot Temperature; Humans; Leucine; Methods; Thiotepa; Urinary Bladder Neoplasms

1980
Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene.
    Nature, 1983, Jun-30, Volume: 303, Issue:5920

    Topics: Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; Glutamine; Humans; Leucine; Lung Neoplasms; Mutation; Oncogenes; Proto-Oncogene Mas; Urinary Bladder Neoplasms

1983
Restoration of E-rosette formation by bestatin in patients with bladder cancer.
    Journal of cancer research and clinical oncology, 1980, Volume: 98, Issue:2

    Topics: Adjuvants, Immunologic; Aged; Anti-Bacterial Agents; Humans; Immunity, Cellular; Leucine; Lymphocytes; Middle Aged; Rosette Formation; Urinary Bladder Neoplasms

1980
Lysozyme enhances monocyte-mediated tumoricidal activity: a potential amplifying mechanism of tumor killing.
    Blood, 1981, Volume: 58, Issue:5

    Topics: Acetylglucosamine; Antineoplastic Agents; Cytotoxicity, Immunologic; Dose-Response Relationship, Immunologic; Hexosephosphates; Humans; Leucine; Melanoma; Monocytes; Muramidase; Urinary Bladder Neoplasms

1981
Selective release of a processed form of interleukin 1 alpha.
    Cytokine, 1994, Volume: 6, Issue:6

    Topics: Calcimycin; Calcium; Calpain; Cell Line; Cysteine Proteinase Inhibitors; Egtazic Acid; Gene Expression; Humans; Interleukin-1; L-Lactate Dehydrogenase; Leucine; Methionine; Molecular Weight; Protein Processing, Post-Translational; Sulfur Radioisotopes; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1994
pH dependent cytotoxicity of N-dodecylimidazole: a compound that acquires detergent properties under acidic conditions.
    British journal of cancer, 1993, Volume: 67, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Count; Cysteine Proteinase Inhibitors; Detergents; Drug Interactions; Hydrogen-Ion Concentration; Imidazoles; Leucine; Mice; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1993
Human monocytes induce a carcinoma cell line to secrete high amounts of nitric oxide.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Sep-01, Volume: 157, Issue:5

    Topics: Arginine; Carcinoma, Transitional Cell; Coculture Techniques; Drug Combinations; Humans; Interleukin-1; Kidney Medulla; Leucine; Macrophage Activation; Monocytes; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Solubility; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Urinary Bladder Neoplasms

1996
NPC-15199, a novel anti-inflammatory agent, mobilizes intracellular Ca2+ in bladder female transitional carcinoma (BFTC) cells.
    The Chinese journal of physiology, 2000, Mar-31, Volume: 43, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium; Carcinoma, Transitional Cell; Female; Fluorenes; Humans; Leucine; Urinary Bladder Neoplasms

2000
Modulation by cis-diamminedichloroplatinum (II) of the susceptibilities of human T24 lined and freshly separated autologous urinary bladder transitional carcinoma cells to peripheral blood lymphocytes and lymphokine activated killer cells.
    The Journal of urology, 1992, Volume: 147, Issue:2

    Topics: Aged; Aged, 80 and over; Carcinoma, Transitional Cell; Cell Line; Chloroquine; Cisplatin; Cytotoxicity, Immunologic; Female; Humans; Killer Cells, Lymphokine-Activated; Leucine; Lymphocytes; Male; Middle Aged; Mitomycin; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1992
Abrogation of the invasion of human bladder tumor cells by using protease inhibitor(s).
    Cancer, 1992, Mar-01, Volume: 69, Issue:5

    Topics: Animals; Carcinoma, Transitional Cell; Cell Movement; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Humans; Laminin; Leucine; Mice; Mice, Nude; Neoplasm Invasiveness; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1992
Multidisciplinary treatment for bladder carcinoma--biological response modifiers and kampo medicines.
    Urologia internationalis, 1991, Volume: 47 Suppl 1

    Topics: Adjuvants, Immunologic; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Combined Modality Therapy; Drugs, Chinese Herbal; Female; Humans; Immunologic Factors; Leucine; Male; Picibanil; Rats; Rats, Inbred Strains; Sizofiran; Urinary Bladder Neoplasms

1991
[Hyperthermic treatment with peplomycin and bestatin in superficial bladder cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Humans; Hyperthermia, Induced; Leucine; Male; Middle Aged; Peplomycin; Urinary Bladder Neoplasms

1985
A trial of the in vitro sensitivity test of anti-cancer drugs using primary cultured urogenital cancer cells.
    Urological research, 1987, Volume: 15, Issue:4

    Topics: Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Cell Survival; Cells, Cultured; Doxorubicin; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Leucine; Male; Testicular Neoplasms; Thymidine; Uridine; Urinary Bladder Neoplasms

1987
DNA binding of 4,4'-methylene-bis(2-chloroaniline) (MOCA) in explant cultures of human and dog bladder.
    Cancer letters, 1987, Volume: 38, Issue:1-2

    Topics: Animals; Benzhydryl Compounds; DNA; Dogs; Humans; Leucine; Methylenebis(chloroaniline); Organ Culture Techniques; Species Specificity; Thymidine; Urinary Bladder; Urinary Bladder Neoplasms

1987
L-isoleucine and L-leucine: tumor promoters of bladder cancer in rats.
    Science (New York, N.Y.), 1986, Feb-21, Volume: 231, Issue:4740

    Topics: Animals; Carcinogens; Carcinoma; Isoleucine; Leucine; Papilloma; Precancerous Conditions; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1986
[Clinical studies of bestatin on genitourinary cancer].
    The Japanese journal of antibiotics, 1985, Volume: 38, Issue:1

    Topics: Adjuvants, Immunologic; Aged; Antibiotics, Antineoplastic; Female; Humans; Kidney Neoplasms; Leucine; Male; Middle Aged; Penile Neoplasms; Prostatic Neoplasms; Ureteral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms

1985
Effect of the bladder carcinogen N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide on nucleic acids and total protein content of bladder epithelium undergoing malignant change.
    Investigative urology, 1974, Volume: 11, Issue:5

    Topics: Animals; Autoradiography; Carcinogens; Cell Nucleus; Cytoplasm; DNA; Formamides; Leucine; Male; Microscopy, Electron; Nitrofurans; Protein Biosynthesis; Rats; RNA; Spectrophotometry; Thiazoles; Thymidine; Tritium; Uridine; Urinary Bladder; Urinary Bladder Neoplasms

1974
[Concentration changes of free amino acids in blood plasma of patients under radiotherapy. (With reference to statistical results)].
    Strahlentherapie, 1972, Volume: 143, Issue:4

    Topics: Alanine; Amino Acids; Bronchial Neoplasms; Carcinoma; Cobalt Isotopes; Dysgerminoma; Esophageal Neoplasms; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leucine; Male; Neoplasms; Phenylalanine; Proline; Radiation Injuries; Sex Factors; Statistics as Topic; Tyrosine; Urinary Bladder Neoplasms; Valine

1972