leucine and Uremia

leucine has been researched along with Uremia in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199023 (58.97)18.7374
1990's5 (12.82)18.2507
2000's7 (17.95)29.6817
2010's2 (5.13)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Chen, HW; Hsieh, CB; Hsieh, TY; Lin, JC1
Kao, JH; Yu, ML1
Chen, Y; McIntire, KL; Rabkin, R; Sood, S1
Jia, W; Lin, J; Liu, Y; Qiu, Y; Su, M; Tao, X; Wang, Y; Zhao, A1
Chen, Y; McIntire, K; Rabkin, R; Roth, R; Sood, S1
Biolo, G; Bosutti, A; Ciocchi, B; Guarnieri, G; Situlin, R; Toigo, G1
Allen, DA; Chesser, AM; Harwood, SM; New, DI; Raftery, MJ; Yaqoob, MM1
Brunini, TM; Ellory, JC; Mann, GE; Mendes Ribeiro, AC; Novaes Malagris, LE; Yaqoob, MM1
Brunini, TM; Ellory, JC; Mann, GE; Mendes Ribeiro, AC; Moss, MB; Roberts, NB; Siqueira, MA; Yaqoob, MM1
Wardle, EN; Williams, R1
Heidland, A; Hörl, WH; Kittel, R1
Delaporte, C; Gros, F1
Battezzati, A; Bianchi, E; Ferrari, G; La Rocca, E; Luzi, L; Perseghin, G; Secchi, A; Spotti, D; Terruzzi, I; Vergani, S1
Biolo, G; Carraro, M; Ciocchi, B; Faccini, L; Guarnieri, G; Morena, G; Situlin, R; Toigo, G; Vasile, A1
Flanigan, MJ; Lim, VS; Yarasheski, KE1
Aronson, JK; Brunini, TM; Ellory, JC; Mann, GE; Mendes Ribeiro, AC; Yaqoob, M1
Holecek, M; Sprongl, L; Tichý, M; Tilser, I2
Burgmann, I; Kuhl, R; Ludwig, D; Wizemann, V1
Alvestrand, A; Bergström, J; Fürst, P1
Djaldetti, M; Levi, J; Mitelman, M1
Chantler, C; Holliday, MA; Keitges, J; MacDonnell, R1
Mitch, W; Walser, M1
Abu-Alfa, A; Mujais, SK1
Flanigan, MJ; Lim, VS; Tsalikian, E1
Hara, Y; Kelly, RA; May, RC; Mitch, WE1
Broyer, M; Dodu, C; Kleinknecht, C; Laouari, D; Rocchiccioli, F1
Broyer, M; Dodu, C; Kamoun, PP; Kleinknecht, C; Laouari, D; Rocchiccioli, F1
Kang, CW; Tungsanga, K; Walser, M1
Betuel, H; Cirillo, D; Esposito, R; Fredel, A; Giordano, C; Lanzetti, N; Manzo, M; Perna, N; Pluvio, M1
Ardelt, W1
Klimkiewicz, E; Szewczyk, Z1
Bergström, J; Bucht, H; Fürst, P; Hultman, E; Josephson, B; Norée, LO; Vinnars, E1
Lacy, WW1
Shear, L1
Burzyński, S; Czerniak, Z1
Burzyński, S1
Clayton, EM; Seligson, D; Seligson, H1
Barry, KG; McCormick, GJ; Shear, L1

Reviews

1 review(s) available for leucine and Uremia

ArticleYear
[Role of essential amino acids in the treatment of chronic renal failure].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1972, Mar-13, Volume: 27, Issue:11

    Topics: Age Factors; Amino Acids; Diet Therapy; Diuresis; Glomerular Filtration Rate; Humans; Isoleucine; Kidney Failure, Chronic; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Threonine; Tryptophan; Uremia; Valine

1972

Trials

1 trial(s) available for leucine and Uremia

ArticleYear
Intravenous nutrition with amino acid solutions in patients with chronic uraemia.
    Acta medica Scandinavica, 1972, Volume: 191, Issue:4

    Topics: Adult; Aged; Amino Acids; Arginine; Diet Therapy; Female; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Nitrogen; Parenteral Nutrition; Phenylalanine; Threonine; Tryptophan; Urea; Uremia; Valine

1972

Other Studies

37 other study(ies) available for leucine and Uremia

ArticleYear
Tacrolimus concentrations were not affected by glecaprevir/pibrentasvir treatment for hepatitis C virus infection in an adult living donor liver transplant recipient with uremia.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2021, Volume: 120, Issue:6

    Topics: Adult; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Cyclopropanes; Drug Combinations; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Leucine; Liver Transplantation; Living Donors; Proline; Pyrrolidines; Quinoxalines; Sulfonamides; Tacrolimus; Uremia

2021
Reply to "Tacrolimus concentrations were not affected by glecaprevir/pibrentasvir treatment for hepatitis C virus infection in an adult living donor liver transplant recipient with uremia".
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2021, Volume: 120, Issue:6

    Topics: Adult; Aminoisobutyric Acids; Benzimidazoles; Cyclopropanes; Drug Combinations; Hepacivirus; Humans; Lactams, Macrocyclic; Leucine; Liver Transplantation; Living Donors; Proline; Pyrrolidines; Quinoxalines; Sulfonamides; Tacrolimus; Uremia

2021
Acute uremia suppresses leucine-induced signal transduction in skeletal muscle.
    Kidney international, 2014, Volume: 85, Issue:2

    Topics: Acute Disease; Acute Kidney Injury; Animals; Carrier Proteins; Disease Models, Animal; Down-Regulation; Insulin-Like Growth Factor I; Interleukin-6; Intracellular Signaling Peptides and Proteins; Leucine; Ligation; Male; Microtubule-Associated Proteins; Muscle, Skeletal; Nutritional Status; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Uremia; Ureter

2014
GC-MS with ethyl chloroformate derivatization for comprehensive analysis of metabolites in serum and its application to human uremia.
    Analytical and bioanalytical chemistry, 2008, Volume: 391, Issue:8

    Topics: Formic Acid Esters; Gas Chromatography-Mass Spectrometry; Humans; Isoleucine; Leucine; Linoleic Acid; Myristic Acid; Reference Standards; Reproducibility of Results; Uremia; Valine

2008
Leucine-stimulated mTOR signaling is partly attenuated in skeletal muscle of chronically uremic rats.
    American journal of physiology. Endocrinology and metabolism, 2011, Volume: 301, Issue:5

    Topics: Animals; Chronic Disease; Drug Evaluation, Preclinical; Kidney; Kidney Failure, Chronic; Leucine; Male; Muscle, Skeletal; Muscular Diseases; Rats; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases; Uremia; Wasting Syndrome; Weight-Bearing

2011
Pentoxifylline acutely reduces protein catabolism in chronically uremic patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 40, Issue:6

    Topics: Amino Acids; Carbon Dioxide; Carbon Isotopes; Chronic Disease; Drug Administration Schedule; Female; Hematologic Agents; Humans; Kidney Failure, Chronic; Leucine; Male; Middle Aged; Oxidation-Reduction; Pentoxifylline; Proteins; Tumor Necrosis Factor-alpha; Uremia

2002
Calpain is activated in experimental uremia: is calpain a mediator of uremia-induced myocardial injury?
    Kidney international, 2003, Volume: 63, Issue:3

    Topics: Acrylates; Animals; Calcium-Binding Proteins; Calpain; Caspase 3; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Disease Models, Animal; Humans; Hypertrophy, Left Ventricular; Leucine; Male; Nephrectomy; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Uremia

2003
Increased nitric oxide synthesis in uraemic platelets is dependent on L-arginine transport via system y(+)L.
    Pflugers Archiv : European journal of physiology, 2003, Volume: 445, Issue:5

    Topics: Adenosine Diphosphate; Amino Acid Transport System y+L; Arginine; Biological Transport; Blood Platelets; Case-Control Studies; Enzyme Inhibitors; Ethylmaleimide; Female; Homocysteine; Humans; Leucine; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Renal Dialysis; Sulfhydryl Reagents; Uremia

2003
Characterization of cationic amino acid transport systems in rat erythrocytes: lack of effect of uraemia on L-arginine influx.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:8

    Topics: Amino Acid Transport System y+; Amino Acid Transport System y+L; Animals; Arginine; Citrulline; Disease Models, Animal; Erythrocytes; Kinetics; Leucine; Lysine; Male; Nephrectomy; Ornithine; Rats; Rats, Wistar; Uremia

2006
Polymorph leucocyte function in uraemia and jaundice.
    Acta haematologica, 1980, Volume: 64, Issue:3

    Topics: Blood Glucose; Cholestasis; Esterases; Humans; Iodine; Jaundice; Leucine; Liver; Liver Cirrhosis, Alcoholic; NADH, NADPH Oxidoreductases; NADPH Oxidases; Necrosis; Neutrophils; Oxidation-Reduction; Peroxidase; Toxins, Biological; Uremia

1980
Effects of high doses of leucine and ketoleucine on glycogen and protein metabolism in acute uremia.
    The American journal of clinical nutrition, 1980, Volume: 33, Issue:7

    Topics: Acute Disease; Animals; Dietary Proteins; Female; Glycogen; Glycogen Synthase; Keto Acids; Kinetics; Leucine; Liver; Muscles; Phosphorylase a; Proteins; Rats; Uremia

1980
In vitro inhibition of protein synthesis by dialysates of plasma from uraemic patients.
    European journal of clinical investigation, 1981, Volume: 11, Issue:2 Suppl 1

    Topics: Adult; Animals; Cell-Free System; Child; Humans; Leucine; Mice; Protein Biosynthesis; Renal Dialysis; Temperature; Uremia

1981
Combined pancreas and kidney transplantation normalizes protein metabolism in insulin-dependent diabetic-uremic patients.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:5

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Hemoglobins; Hormones; Humans; Hyperinsulinism; Immunosuppression Therapy; Keto Acids; Kidney Failure, Chronic; Kidney Transplantation; Leucine; Male; Nitrogen; Oxidation-Reduction; Pancreas Transplantation; Proteins; Uremia; Uveitis, Posterior

1994
Relationship between whole-body protein turnover and serum creatinine in chronically uremic patients.
    Mineral and electrolyte metabolism, 1998, Volume: 24, Issue:4

    Topics: Adult; Aged; Body Mass Index; Carbon Isotopes; Creatinine; Female; Humans; Hydrogen-Ion Concentration; Keto Acids; Kidney Failure, Chronic; Kinetics; Leucine; Male; Middle Aged; Nutritional Status; Proteins; Regression Analysis; Uremia

1998
The effect of uraemia, acidosis, and dialysis treatment on protein metabolism: a longitudinal leucine kinetic study.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:7

    Topics: Acidosis; Case-Control Studies; Female; Humans; Kidney Failure, Chronic; Leucine; Longitudinal Studies; Male; Middle Aged; Nutrition Disorders; Nutritional Status; Peritoneal Dialysis, Continuous Ambulatory; Proteins; Renal Dialysis; Sodium Bicarbonate; Uremia

1998
Identification of system y+L as the high-affinity transporter for L-arginine in human platelets: up-regulation of L-arginine influx in uraemia.
    Pflugers Archiv : European journal of physiology, 1999, Volume: 438, Issue:4

    Topics: Amino Acid Transport Systems, Basic; Arginine; Binding, Competitive; Biological Transport; Blood Platelets; Carrier Proteins; Glutamine; Humans; Kidney Failure, Chronic; Kinetics; Leucine; Membrane Proteins; Potassium; Sodium; Up-Regulation; Uremia

1999
Leucine and protein metabolism after bilateral nephrectomy in rats: the role of hepatic tissue.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 2000, Volume: 200, Issue:1

    Topics: Acute Disease; Amino Acids, Branched-Chain; Animals; In Vitro Techniques; Kinetics; Leucine; Liver; Male; Nephrectomy; Perfusion; Proteins; Rats; Rats, Wistar; Uremia

2000
Leucine and protein metabolism in rats with chronic renal insufficiency.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2001, Volume: 53, Issue:1

    Topics: Acidosis; Animals; Body Weight; Cholesterol; Creatinine; Disease Models, Animal; Eating; Isoleucine; Kidney Failure, Chronic; Leucine; Male; Muscle, Skeletal; Nephrectomy; Proteins; Rats; Rats, Wistar; Urea; Uremia; Valine

2001
Digestive-absorptive function of the intestinal brush border in uremia.
    The American journal of clinical nutrition, 1978, Volume: 31, Issue:9

    Topics: alpha-Glucosidases; Animals; Disaccharidases; gamma-Glutamyltransferase; Intestinal Absorption; Intestinal Mucosa; Kidney; Leucine; Male; Rats; Uremia

1978
Intracellular free amino acids in patients treated with regular haemodialysis (HD).
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1979, Volume: 16

    Topics: Amino Acids; Amino Acids, Branched-Chain; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Renal Dialysis; Threonine; Uremia; Valine

1979
Functional activity of uremic erythroblast incubated in autologous and homologous plasma.
    Blut, 1979, Jun-18, Volume: 38, Issue:6

    Topics: Adult; Aged; Blood Proteins; DNA; Erythroblasts; Erythrocytes; Female; Humans; Leucine; Male; Middle Aged; RNA; Thymidine; Uremia; Uridine

1979
Effect of uremia on nutritionally-induced variations in protein metabolism.
    Kidney international, 1977, Volume: 11, Issue:4

    Topics: Alanine; Amino Acids; Animals; Blood Proteins; Eating; Extracellular Space; Fasting; Insulin; Intracellular Fluid; Leucine; Muscles; Nitrogen; Nutritional Physiological Phenomena; Oxidation-Reduction; Protein Biosynthesis; Rats; Urea; Uremia

1977
Nitrogen balance of uremic patients receiving branched-chain ketoacids and the hydroxy-analogue of methionine as substitutes for the respective amino acids.
    Clinical nephrology, 1977, Volume: 8, Issue:2

    Topics: Amino Acids, Essential; Glomerular Filtration Rate; Glycine; Humans; Isoleucine; Leucine; Methionine; Nitrogen; Uremia; Valine

1977
Uremic pancreopathy: impaired secretory function in vitro.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1992, Volume: 20, Issue:6

    Topics: Animals; Carbachol; Cell Count; Cell Survival; Cells, Cultured; DNA; Kidney Failure, Chronic; Leucine; Male; Pancreas; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; Tritium; Uremia

1992
Augmentation of protein degradation by L-triiodothyronine in uremia.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:12

    Topics: Adult; Chromatography; Energy Intake; Energy Metabolism; Female; Food Analysis; Humans; Leucine; Male; Middle Aged; Nitrogen; Plasma; Proteins; Radioimmunoassay; Renal Dialysis; Thyroid Function Tests; Triiodothyronine; Urea; Uremia

1989
Acidosis, not azotemia, stimulates branched-chain, amino acid catabolism in uremic rats.
    Kidney international, 1987, Volume: 32, Issue:6

    Topics: Acidosis; Amino Acids, Branched-Chain; Animals; Dietary Proteins; Kidney Failure, Chronic; Leucine; Male; Muscles; Nephrectomy; Rats; Rats, Inbred Strains; Uremia; Valine

1987
Conversion efficiency of two branched-chain alpha ketoanalogs in normal and uremic rats.
    Kidney international. Supplement, 1987, Volume: 22

    Topics: Amino Acids, Branched-Chain; Animals; Keto Acids; Leucine; Male; Rats; Rats, Inbred Strains; Uremia; Valine

1987
Efficiency of substitution of 2-ketoisocaproic acid and 2-ketoisovaleric acid in the diet of normal and uremic growing rats.
    The American journal of clinical nutrition, 1986, Volume: 44, Issue:6

    Topics: Animals; Diet; Growth; Hemiterpenes; Keto Acids; Leucine; Male; Nitrogen; Nutritive Value; Rats; Rats, Inbred Strains; Urea; Uremia; Valine

1986
Utilization of alpha-ketoisocaproate for protein synthesis in uremic rats.
    Kidney international, 1986, Volume: 30, Issue:6

    Topics: Animals; Blood Proteins; Body Weight; Keto Acids; Kidney Failure, Chronic; Leucine; Nephrectomy; Protein Biosynthesis; Radioisotopes; Rats; Rats, Inbred Strains; Renal Artery Obstruction; Tissue Distribution; Uremia

1986
The effect of branch chain amino acids on the proliferation of normal and uremic cells.
    Kidney international. Supplement, 1985, Volume: 17

    Topics: Cell Division; Cells, Cultured; Humans; Isoleucine; Kidney Failure, Chronic; Leucine; Lymphocytes; Renal Dialysis; Uremia; Valine

1985
[Studies on the clinical significance of glycyl-L-leucine dipeptidase in blood platelets].
    Arztliche Forschung, 1972, Aug-10, Volume: 26, Issue:8

    Topics: Adult; Age Factors; Aprotinin; Blood Platelets; Blood Preservation; Carcinoma; Contraceptives, Oral; Cyclophosphamide; Cystitis; Dipeptidases; Female; Glycine; Humans; Labor, Obstetric; Leucine; Male; Menstruation; Ovarian Neoplasms; Pregnancy; Sex Factors; Temperature; Uremia

1972
Uptake of individual amino acids by perfused rat liver: effect of acute uremia.
    The American journal of physiology, 1970, Volume: 219, Issue:3

    Topics: Amino Acids; Animals; Fasting; Female; Glutamates; Isoleucine; Leucine; Liver; Lysine; Perfusion; Protein Biosynthesis; Rats; Serine; Threonine; Uremia; Valine

1970
Internal redistribution of tissue protein synthesis in uremia.
    The Journal of clinical investigation, 1969, Volume: 48, Issue:7

    Topics: Amino Acids; Animals; Carbon Isotopes; Leucine; Liver; Male; Muscles; Myocardium; Nephrectomy; Organ Size; Protein Biosynthesis; Rats; Uremia

1969
Free amino acids in serum of patients with chronic renal insufficiency.
    Clinica chimica acta; international journal of clinical chemistry, 1969, Volume: 24, Issue:3

    Topics: Adult; Aged; Alanine; Amino Acids; Analysis of Variance; Arginine; Chromatography, Paper; Cystine; Female; Glomerulonephritis; Glutamates; Glycine; Humans; Leucine; Lysine; Male; Middle Aged; Phenylalanine; Pyelonephritis; Threonine; Urea; Uremia

1969
Bound amino acids in serum of patients with chronic renal insufficiency.
    Clinica chimica acta; international journal of clinical chemistry, 1969, Volume: 25, Issue:2

    Topics: Adult; Aged; Amino Acids; Analysis of Variance; Aspartic Acid; Chromatography, Paper; Female; Glomerulonephritis; Glutamates; Glycine; Humans; Kidney Failure, Chronic; Leucine; Lysine; Male; Methods; Middle Aged; Phenylalanine; Pyelonephritis; Threonine; Uremia

1969
Inhibition of protein synthesis by N-methyl-2-pyridone-5-formamidoacetic acid and other compounds isolated from uremic patients.
    The Yale journal of biology and medicine, 1965, Volume: 38, Issue:3

    Topics: Antimetabolites; Blood; Kidneys, Artificial; Leucine; Peritoneal Dialysis; Protein Biosynthesis; Pyridines; Tritium; Uremia

1965
Alteration of hepatic protein synthesis in acute uremia.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 122, Issue:1

    Topics: Animals; Fasting; In Vitro Techniques; Leucine; Liver; Protein Biosynthesis; Rats; Subcellular Fractions; Uremia

1966