leucine and Thalassemias

leucine has been researched along with Thalassemias in 81 studies

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199080 (98.77)18.7374
1990's1 (1.23)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BURKA, ER; MARKS, PA2
SIEGAL, S1
HEYWOOD, JD; KARON, M; WEISSMAN, S1
RIEDER, RF; WEATHERALL, DJ1
GABUZDA, TG; GARDNER, FH; NATHAN, DG1
Jeffries, I; Karon, M; Weissman, SM1
Garlick, RL; Himelstein, AL; Mazer, JS; Shaeffer, JR; Stamatoyannopoulos, G1
Fessas, P; Karoulias, A; Loukopoulos, D1
Ballas, SK; Burka, ER; Gill, FM1
Bernini, LF; Flavell, RA; Heerspink, W; Oort, M; Roos, D1
Atwater, J; Ballas, SK; Walker, BK1
de Castro, CM; Devlin, B; Fleenor, DE; Kaufman, RE; Lee, ME1
Changloah, L; Flatz, G; Matragoon, S; Sanguansermsri, T1
Cividalli, G; Di Segni, G; Kaempfer, R; Kerem, H; Rachmilewitz, EA1
Alter, BP; Fairweather, D; Hobbins, JC; Mahoney, MJ; Modell, CB; Nathan, DG1
Corley, CC; Gravely, M; Huisman, TH; Milner, PF; Pomeroy, WL; Wilson, JB1
Borgatti, L; Conconi, F; Del Senno, L; Ferrarese, P; Labie, D; Menini, C; Vullo, C1
Clegg, JB; Weatherall, DJ; Willcox, MC1
Fukumaki, Y; Kobayashi, Y; Komatsu, N; Miura, Y; Miyaji, T; Ohba, Y1
Popp, RA; Wawrzyniak, CJ1
Conconi, F; Dreyfus, JC; Labie, D; Vibert, M1
Clegg, JB; Knox-Macaulay, HH; Pembrey, ME; Weatherall, DJ1
Conconi, F; del Senno, L2
Gaburro, D; Vigi, V; Volpato, S1
Feldman, R; Rieder, RF1
Bunch, C; Clegg, JB; Hopkins, CR; Knox-Macaulay, HH; Temperley, IJ; Weatherall, DJ1
Clegg, JB; Knox-Macaulay, HH; Roberts, AV; Weatherall, DJ1
Labie, A; Pagnier, J; Wajcman, H1
Schwartz, E3
Atwater, J; Friedman, S; Gill, FM; Schwartz, E1
Conconi, F; Del Senno, L; Pontremoli, S; Rowley, PT; Volpato, S1
Kosciolek, B; Rowley, PT1
Clegg, JB; Weatherall, DJ2
Bank, A; Dow, LW; Grossbard, E; Terada, M1
Bank, A; Dow, LW; Grossbard, E; Marks, PA; Metafora, S; Natta, C; Terada, M1
Bank, A; Banks, J; Marks, PA; Natta, C; Niazi, G1
Cividalii, G; Frigoletto, F; Kan, YW; Nathan, DG1
Anderson, WF2
Gill, FM; Schwartz, E1
Adams, JG1
Rieder, RF1
Gallo, E; Mazza, U; Pich, PG; Pinna, G; Pugliatti, L; Ricco, G1
Lang, A; Lehmann, H; van Enk, A; White, JM1
Bank, A; Dow, LW; Farace, MG; Ford, S; Natta, C; O'Donnell, JV1
Borgatti, L; Conconi, F; Del Senno, L1
Friedman, S; Hamilton, RW; Schwartz, E1
Benz, EJ; Forget, BG; Swerdlow, PS1
Gallo, E; Mazza, U; Pich, PG; Ricco, G1
King-Lewis, PA; Lang, A; Lehmann, H1
Bank, A; Ford, S; Natta, CL; Niazi, GA1
DeSimone, J; Kleve, L; Longley, MA; Shaeffer, J1
Bank, A; Marks, PA1
Christakopoulos, P; Elias-Kesse, M; Gyftaki, E; Malamos, B1
Alevizou-Terzaki, V; Gyftaki, E; Kesse-Elias, M; Koukoulommati, A1
Friedman, S; Oski, FA; Schwartz, E1
Kan, YW; Lodish, HF; Nathan, DG1
Ramot, B; Shchory, M1
Forget, BG; Kan, YW; Nathan, DG1
Bannister, D; Clegg, JB; MacNeish, AS; Mann, JR; Weatherall, DJ; Wood, WG1
Atwater, J; Gill, F; Schwartz, E1
Anderson, WF; Nienhuis, AW1
Kan, YW; Nathan, DG; Schwartz, E2
Bank, A; Braverman, AS1
Anderson, WF; Gilbert, JM; Nienhuis, AW; Thornton, AG1
Huehns, ER; Latter, A; Modell, CB; Steadman, JH1
Kan, YW; Nathan, DG2
Bargellesi, A; Conconi, F; Pontremoli, S1
Clegg, JB; Na-Nakorn, S; Wasi, P; Weatherall, DJ2
Bank, A; O'Donnell, JV1
Honig, GR; Mason, RG; Rowan, BQ1
Heywood, D; Karon, M; Weissman, S1
Clegg, JB; Naughton, MA; Weatherall, DJ1

Reviews

3 review(s) available for leucine and Thalassemias

ArticleYear
The clinical and chemical heterogeneity of the beta-thalassemias.
    Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0

    Topics: Black People; Blood Transfusion; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Chromatography, Gel; Erythrocyte Aging; Erythrocytes; Fetal Hemoglobin; Globins; Hemoglobins, Abnormal; Heterozygote; Homozygote; Humans; Inclusion Bodies; Leucine; Male; Middle Aged; Peptide Fragments; Reticulocytes; Thalassemia

1974
Variation in beta-alpha synthesis ratios in thalassemia and hemoglobinopathies.
    Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0

    Topics: Anemia, Hemolytic, Autoimmune; Anemia, Sickle Cell; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Erythrocyte Aging; Erythrocytes; Globins; Hemoglobin C Disease; Hemoglobinopathies; Heterozygote; Homozygote; Humans; Leucine; Peptide Chain Termination, Translational; Peptide Fragments; RNA, Messenger; Thalassemia; Tritium; Trypsin; Valine

1974
Hemoglobin synthesis in thalassemia.
    Series haematologica (1968), 1971, Volume: 4, Issue:3

    Topics: Amino Acids; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Ethnicity; Globins; Hemoglobins; Heterozygote; Homozygote; Humans; Leucine; Peptides; Rabbits; Reticulocytes; RNA, Messenger; Thalassemia; Tritium

1971

Other Studies

78 other study(ies) available for leucine and Thalassemias

ArticleYear
RIBOSOMES ACTIVE IN PROTEIN SYNTHESIS IN HUMAN RETICULOCYTES: A DEFECT IN THALASSEMIA MAJOR.
    Nature, 1963, Aug-17, Volume: 199

    Topics: Anemia; Anemia, Sickle Cell; beta-Thalassemia; Carbon Isotopes; Hemoglobins; Humans; Isoleucine; Leucine; Nucleoproteins; Proteins; Reticulocytes; Ribosomes; Thalassemia

1963
THE THALASSEMIA SYNDROMES. BIOCHEMICAL, GENETIC AND CLINICAL CONSIDERATIONS.
    The American journal of medicine, 1964, Volume: 36

    Topics: Biochemical Phenomena; Biochemistry; DNA; Genetics, Medical; Hemoglobins; Hemoglobins, Abnormal; Isoleucine; Leucine; Proteins; Reticulocytes; RNA; Syndrome; Thalassemia

1964
AMINO ACIDS: INCORPORATION INTO ALPHA- AND BETA-CHAINS OF HEMOGLOBIN BY NORMAL AND THALASSEMIC RETICULOCYTES.
    Science (New York, N.Y.), 1964, Oct-23, Volume: 146, Issue:3643

    Topics: Amino Acids; Anemia, Sickle Cell; Carbon Isotopes; Globins; Hemoglobins; Humans; Leucine; Leukemia; Proteins; Research; Reticulocytes; Thalassemia; Valine

1964
HEMOGLOBINS A AND F: FORMATION IN THALASSEMIA AND OTHER HEMOLYTIC ANEMIAS.
    Science (New York, N.Y.), 1964, May-01, Volume: 144, Issue:3618

    Topics: Anemia, Hemolytic; Carbon Isotopes; DNA; Erythropoiesis; Fetal Hemoglobin; Hemoglobin A; Hemoglobins; Hemoglobins, Abnormal; Histocytochemistry; Humans; Isoleucine; Leucine; Proteins; Reticulocytes; Ribosomes; RNA; Thalassemia

1964
STUDIES ON HEMOGLOBIN BIOSYNTHESIS: ASYNCHRONOUS SYNTHESIS OF HEMOGLOBIN A AND HEMOGLOBIN A2 BY ERYTHROCYTE PRECURSORS.
    The Journal of clinical investigation, 1965, Volume: 44

    Topics: Anemia; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Pernicious; Anemia, Sickle Cell; Blood Protein Electrophoresis; Bone Marrow; Chromatography; Folic Acid; Folic Acid Deficiency; Hemoglobin A2; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Iron; Iron Isotopes; Leucine; Metabolic Diseases; Primary Myelofibrosis; Proteins; Pyruvate Kinase; Reticulocytes; Spherocytosis, Hereditary; Thalassemia; Vitamin B Deficiency

1965
THE METABOLISM OF THE INDIVIDUAL C14 LABELED HEMOGLOBINS IN PATIENTS WITH H-THALASSEMIA, WITH OBSERVATIONS ON RADIOCHROMATE BINDING TO THE HEMOGLOBINS DURING RED CELL SURVIVAL.
    The Journal of clinical investigation, 1965, Volume: 44

    Topics: Blood Protein Electrophoresis; Carbon Isotopes; Cell Survival; Centrifugation; Chromium Isotopes; Erythrocytes; Glycine; Hemoglobins; Hemoglobins, Abnormal; Humans; Leucine; Proteins; Splenectomy; Thalassemia

1965
The synthesis of alpha, beta, and delta peptide chains by reticulocytes from subjects with thalassemia or hemoglobin Lepore.
    The Journal of laboratory and clinical medicine, 1967, Volume: 69, Issue:2

    Topics: Hemoglobins, Abnormal; Histidine; Humans; In Vitro Techniques; Leucine; Peptide Biosynthesis; Reticulocytes; Thalassemia; Valine

1967
Acetylation of human fetal hemoglobin occurs throughout erythroid cell maturation.
    Biochimica et biophysica acta, 1984, May-25, Volume: 799, Issue:1

    Topics: Acetylation; Adult; Blood Cells; Bone Marrow; Cells, Cultured; Erythroblasts; Female; Fetal Blood; Fetal Hemoglobin; Humans; Infant; Infant, Newborn; Leucine; Macromolecular Substances; Pregnancy; Thalassemia; Tissue Distribution; Trypsin

1984
Proteolysis in thalassemia: studies with protease inhibitors.
    Annals of the New York Academy of Sciences, 1980, Volume: 344

    Topics: Aminobutyrates; Cell-Free System; Erythrocytes; Globins; Hemoglobins; Humans; Leucine; Molecular Conformation; Peptide Fragments; Phenanthrolines; Protease Inhibitors; Proteins; Thalassemia

1980
Abnormal red cell membrane proteolytic activity in severe heterozygous beta-thalassemia.
    The Journal of laboratory and clinical medicine, 1982, Volume: 99, Issue:2

    Topics: Bone Marrow; Erythrocyte Membrane; Erythrocytes; Female; Globins; Hemoglobin A; Heterozygote; Humans; In Vitro Techniques; Leucine; Male; Middle Aged; Peptide Hydrolases; Protease Inhibitors; Thalassemia

1982
Haemolytic disease of the newborn and chronic anaemia induced by gamma beta thalassaemia in a Dutch family.
    British journal of haematology, 1981, Volume: 48, Issue:2

    Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Congenital; Child; Child, Preschool; Erythroblastosis, Fetal; Female; Globins; Humans; Hyperbilirubinemia, Hereditary; Infant, Newborn; Leucine; Male; Middle Aged; Netherlands; Pedigree; Pregnancy; Thalassemia

1981
Globin synthesis studies in a person heterozygous for alpha-thalassemia-2, Hb S and Hb G Philadelphia.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Jan-01, Volume: 100, Issue:1

    Topics: Adult; Black People; Chromatography; Female; Globins; Hemoglobin, Sickle; Hemoglobins, Abnormal; Heterozygote; Humans; Leucine; Thalassemia; Time Factors; United States

1980
A novel beta-globin mutation, beta Durham-NC [beta 114 Leu-->Pro], produces a dominant thalassemia-like phenotype.
    Blood, 1994, Feb-15, Volume: 83, Issue:4

    Topics: Adult; Amino Acid Sequence; Base Sequence; Codon; Computer Graphics; DNA; DNA Primers; Erythrocytes; Exons; Female; Globins; Humans; Leucine; Leukocytes; Male; Models, Molecular; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Proline; Protein Structure, Secondary; Thalassemia

1994
Hemoglobin Suan-Dok (alpha 2 109 (G16) Leu replaced by Arg beta 2): an unstable variant associated with alpha-thalassemia.
    Hemoglobin, 1979, Volume: 3, Issue:2-3

    Topics: Adult; Amino Acids; Arginine; Child; Child, Preschool; Female; Globins; Hemoglobins, Abnormal; Humans; Leucine; Male; Peptide Fragments; Reticulocytes; Thailand; Thalassemia

1979
Absence of functional beta-globin messenger RNA in Kurdish Jews with beta0-thalassemia.
    Israel journal of medical sciences, 1978, Volume: 14, Issue:11

    Topics: Cell-Free System; Ethnicity; Globins; Homozygote; Humans; Israel; Jews; Leucine; Micrococcal Nuclease; Peptide Initiation Factors; Protein Biosynthesis; Proteins; Reticulocytes; RNA, Messenger; Thalassemia; Triticum

1978
Prenatal diagnosis of hemoglobinopathies: detection of alpha-thalassemia trait and of sickle cell disease in utero.
    Hemoglobin, 1977, Volume: 1, Issue:4

    Topics: Anemia, Sickle Cell; Blood; Female; Fetal Hemoglobin; Globins; Hemoglobin A; Hemoglobin, Sickle; Heterozygote; Humans; Infant, Newborn; Leucine; Placenta; Pregnancy; Prenatal Diagnosis; Thalassemia

1977
Thalassemia intermedia caused by heterozygosity for both beta-thalassemia and hemoglobin Saki [beta 14 (A11) Leu replaced by Pro].
    American journal of hematology, 1976, Volume: 1, Issue:3

    Topics: Adolescent; Hemoglobins; Heterozygote; Humans; Leucine; Male; Peptides; Proline; Thalassemia

1976
Appearance of beta globin synthesis in erythroid cells of Ferrara beta -o-thalassaemic patients following blood transfusion.
    Nature, 1975, Mar-20, Volume: 254, Issue:5497

    Topics: Blood Transfusion; Globins; Homozygote; Humans; Leucine; Peptides; Reticulocytes; Thalassemia

1975
Homozygous beta thalassaemia in Liberia.
    Journal of medical genetics, 1975, Volume: 12, Issue:2

    Topics: Black People; Erythrocyte Count; Female; Fetal Hemoglobin; Hemoglobinometry; Hemoglobins; Homozygote; Humans; Leucine; Liberia; Male; Pedigree; Thalassemia; Tritium

1975
A novel globin structural mutant, Showa-Yakushiji (beta 110 Leu-Pro) causing a beta-thalassemia phenotype.
    Blood, 1987, Volume: 70, Issue:5

    Topics: Amino Acid Sequence; Base Sequence; DNA Restriction Enzymes; Genes; Globins; Humans; Leucine; Mutation; Phenotype; Proline; Thalassemia

1987
Detection of an unstable murine hemoglobin.
    Biochemical and biophysical research communications, 1986, Sep-14, Volume: 139, Issue:2

    Topics: 1-Propanol; Amino Acid Sequence; Animals; Female; Globins; Hemoglobin A; Leucine; Macromolecular Substances; Male; Mice; Mice, Inbred Strains; Protein Denaturation; Reticulocytes; Thalassemia

1986
An attempt at demonstrating the existence of a nonsense mutation in -thalassemia.
    European journal of biochemistry, 1972, May-23, Volume: 27, Issue:2

    Topics: Beta-Globulins; Chromatography, Ion Exchange; Genes; Globins; Homozygote; Humans; Leucine; Mutation; Peptides; Reticulocytes; Thalassemia; Tritium; Trypsin

1972
Thalassaemia in the British.
    British medical journal, 1973, Jul-21, Volume: 3, Issue:5872

    Topics: Adolescent; Anemia; Beta-Globulins; Carbon Isotopes; Diagnosis, Differential; Female; Fetal Hemoglobin; Hemoglobin H; Hemoglobinopathies; Humans; Leucine; Male; Thalassemia; United Kingdom

1973
Defective translational control in the beta-thalassemia of Ferrara.
    Advances in experimental medicine and biology, 1974, Volume: 44, Issue:1

    Topics: Beta-Globulins; Blood Transfusion; Chromatography; Homozygote; Humans; Italy; Leucine; Mutation; Peptide Initiation Factors; Protein Biosynthesis; Reticulocytes; Ribosomes; RNA, Messenger; Thalassemia; Transcription, Genetic; Tritium

1974
Diagnosis of beta thalassaemia in the newborn by means of haemoglobin synthesis.
    Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:5

    Topics: Alpha-Globulins; Beta-Globulins; Chromatography; Erythrocyte Count; Female; Hemoglobins; Humans; Infant, Newborn; Infant, Newborn, Diseases; Leucine; Lysine; Male; Osmotic Fragility; Thalassemia; Tritium; Valine

1970
The interaction of hemoglobin E with beta thalassemia: a study of hemoglobin synthesis in a family of mixed Burmese and Iranian origin.
    Blood, 1973, Volume: 42, Issue:5

    Topics: Carrier State; Cell Survival; Child, Preschool; Chromium Radioisotopes; Electrophoresis, Starch Gel; Erythrocytes; Female; Fetal Hemoglobin; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Iran; Leucine; Myanmar; Pedigree; Peptides; Suppression, Genetic; Thalassemia; Tritium

1973
A genetically determined disorder with features both of thalassaemia and congenital dyserythropoietic anaemia.
    British journal of haematology, 1973, Volume: 24, Issue:6

    Topics: Anemia; Bone Marrow Cells; Carbon Isotopes; Cell Division; Cholelithiasis; Erythrocytes; Erythrocytes, Abnormal; Erythropoiesis; Female; Genes, Dominant; Hemoglobins; Humans; Inclusion Bodies; Ireland; Jaundice; Leucine; Male; Microscopy, Electron; Middle Aged; Potassium; Sodium; Splenectomy; Splenomegaly; Thalassemia

1973
Defect in hemoglobin synthesis possibly due to a disturbed association.
    FEBS letters, 1974, Sep-01, Volume: 45, Issue:1

    Topics: Chromatography, Gel; Erythrocytes; Hemoglobins, Abnormal; Heterozygote; Homozygote; Humans; Leucine; Reticulocytes; Spectrophotometry; Spectrophotometry, Ultraviolet; Thalassemia; Time Factors; Tritium

1974
Abnormal globin synthesis in thalassemic red cells.
    Seminars in hematology, 1974, Volume: 11, Issue:4

    Topics: Amino Acids; Animals; Black People; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Densitometry; Erythrocytes; Fetal Hemoglobin; Globins; Glucose; Hemin; Hemoglobin, Sickle; Hemolysis; Heterozygote; Homozygote; Humans; Leucine; Peptides; Rabbits; Ribosomes; RNA, Messenger; RNA, Transfer; Thalassemia; Tritium; tRNA Methyltransferases

1974
Alpha-thalassemia in Negro infants.
    Pediatric research, 1974, Volume: 8, Issue:12

    Topics: Black or African American; Carbon Radioisotopes; Chromatography, Gel; Electrophoresis, Starch Gel; Erythrocyte Count; Female; Hematocrit; Hemoglobins; Hemoglobins, Abnormal; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Leucine; Male; Pennsylvania; Serum Globulins; Thalassemia

1974
Induction of -globin synthesis in the -thalassaemia of Ferrara.
    Nature: New biology, 1972, Jul-19, Volume: 238, Issue:81

    Topics: Cell-Free System; Chromatography; Globins; Humans; Leucine; Peptides; Reticulocytes; Ribosomes; Thalassemia; Tritium

1972
Distinction between two types of beta-thalassaemia by inducibility of the cell-free synthesis of beta-chains by nonthalassaemic soluble fraction.
    Nature: New biology, 1972, Oct-25, Volume: 239, Issue:95

    Topics: Cell-Free System; Ethnicity; Hemoglobins; Homozygote; Humans; Leucine; Ribosomes; Thalassemia; Tritium

1972
Haemoglobin synthesis during erythroid maturation in -thalassaemia.
    Nature: New biology, 1972, Dec-06, Volume: 240, Issue:101

    Topics: Anemia, Sickle Cell; Bone Marrow; Carbon Isotopes; Chromatography, Gel; Hemoglobins; Heterozygote; Humans; Leucine; Molecular Weight; Reticulocytes; RNA, Messenger; Thalassemia

1972
Decreased globin messenger RNA activity associated with polyribosomes in thalassaemia.
    Nature: New biology, 1973, Feb-14, Volume: 241, Issue:111

    Topics: Adult; Carbon Isotopes; Cell Fractionation; Cell-Free System; Chromatography; Female; Globins; Hemoglobin H; Hemoglobinopathies; Humans; Leucine; Polyribosomes; Reticulocytes; RNA, Messenger; Thalassemia; Tritium

1973
Globin synthesis of intact cells and activity of isolated mRNA in -thalassaemia.
    Nature: New biology, 1973, May-23, Volume: 243, Issue:125

    Topics: Animals; Cell-Free System; Erythrocytes; Globins; Humans; Leucine; Polyribosomes; Rabbits; RNA, Messenger; RNA, Ribosomal; Thalassemia; Tritium

1973
Decreased beta globin mRNA activity in bone marrow cells in homozygous and heterozygous beta thalassaemia.
    Nature: New biology, 1973, Aug-29, Volume: 244, Issue:139

    Topics: Anemia, Hemolytic, Autoimmune; Bone Marrow; Bone Marrow Cells; Cell-Free System; Globins; Heterozygote; Homozygote; Humans; Leucine; Reticulocytes; RNA, Messenger; Thalassemia; Tritium

1973
Intrauterine diagnosis of thalassemia.
    Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0

    Topics: Anemia, Sickle Cell; Blood; Carbon Radioisotopes; Chromatography, Ion Exchange; Erythrocytes; Female; Fetus; Gestational Age; Hemagglutination; Humans; Immune Sera; Leucine; Methods; Peptide Fragments; Placenta; Pregnancy; Prenatal Diagnosis; Thalassemia; Tritium; Umbilical Cord

1974
Isolation and translation of messenger RNA from beta-thalassemia red cells.
    Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0

    Topics: Anemia; Anemia, Sickle Cell; Animals; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Erythroblastosis, Fetal; Erythrocytes; Female; Globins; Glycine; Humans; Leucine; Methionine; Peptide Fragments; Peptide Initiation Factors; Phenylhydrazines; Pregnancy; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; RNA, Transfer; Thalassemia; Valine

1974
Regulation of hemoglobin synthesis in beta-thalassemia.
    Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0

    Topics: Anemia, Sickle Cell; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Chromatography, Ion Exchange; Erythrocytes; Globins; Hemoglobins; Hemoglobins, Abnormal; Hemolysis; Heterozygote; Homozygote; Humans; Italy; Leucine; Peptide Fragments; Thalassemia

1974
The molecular defect of Ferrara beta-thalassemia.
    Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0

    Topics: Blood Transfusion; Cell Survival; Chromatography, Ion Exchange; Erythrocytes; Globins; Hemolysis; Heterozygote; Homozygote; Humans; Italy; Leucine; Peptide Fragments; Protein Biosynthesis; RNA, Messenger; Thalassemia; Transcription, Genetic; Tritium

1974
Cell-free synthesis of globin chains: an overview.
    Annals of the New York Academy of Sciences, 1974, Nov-29, Volume: 241, Issue:0

    Topics: Anemia, Sickle Cell; Animals; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Globins; Humans; Kinetics; Leucine; Peptide Chain Initiation, Translational; Polyribosomes; Protein Biosynthesis; Rabbits; Reticulocytes; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Ribosomal; RNA, Transfer; Thalassemia; Time Factors; Tritium

1974
Hemoglobin Ann Arbor: disturbance in the coordinated biosynthesis of globin chains?
    Annals of the New York Academy of Sciences, 1974, Nov-29, Volume: 241, Issue:0

    Topics: Alleles; Amino Acids; Carbon Radioisotopes; Female; Globins; Hemoglobins, Abnormal; Heterozygote; Humans; Isotope Labeling; Israel; Kinetics; Leucine; Male; Michigan; Pedigree; Protein Biosynthesis; Thalassemia; Time Factors; Tritium; Valine

1974
A case of haemoglobin J Sardegna- -thalassaemia double heterozygosis.
    Acta haematologica, 1972, Volume: 47, Issue:5

    Topics: Amino Acids; Blood Protein Electrophoresis; Carbon Isotopes; Chromatography, DEAE-Cellulose; Glycerophosphates; Hemoglobinopathies; Hemoglobins, Abnormal; Heterozygote; Humans; Italy; Leucine; Male; Oxygen; Pedigree; Peptides; Thalassemia

1972
Benign obstetric history in women with sickle-cell anaemia associated with -thalassaemia.
    British medical journal, 1972, Dec-02, Volume: 4, Issue:5839

    Topics: Adult; Anemia, Sickle Cell; Black People; Bone Marrow; Female; Fetal Hemoglobin; Ghana; Hemoglobins, Abnormal; Humans; Iron; Leucine; Pregnancy; Pregnancy Complications, Hematologic; Social Class; Thalassemia; Tritium; United States

1972
Changes in globin synthesis with erythroid cell maturation in sickle thalassemia.
    Blood, 1973, Volume: 41, Issue:3

    Topics: Anemia, Sickle Cell; Blood Protein Electrophoresis; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Chromatography; Female; Globins; Hemoglobins, Abnormal; Heterozygote; Humans; Leucine; Male; Thalassemia

1973
Reduced rate of -globin mRNA translation in -thalassemia.
    European journal of biochemistry, 1973, Feb-01, Volume: 32, Issue:3

    Topics: Erythrocytes; Globins; Humans; Leucine; Protein Biosynthesis; Reticulocytes; RNA, Messenger; Temperature; Thalassemia; Tritium

1973
Beta-thalassemia in the American Negro.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Aged; Black People; Carbon Isotopes; Child; Child, Preschool; Chromatography; Female; Globins; Heterozygote; Homozygote; Humans; Leucine; Male; Middle Aged; Pedigree; Thalassemia; United States

1973
Globin messenger RNA in hemoglobin H disease.
    Blood, 1973, Volume: 42, Issue:6

    Topics: Adult; Animals; Carbon Radioisotopes; Cell-Free System; Globins; Hemoglobin H; Hemoglobinopathies; Humans; Leucine; Male; Neoplasm Proteins; Neoplasms, Experimental; Potassium Chloride; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Thalassemia

1973
[Study on a case of double heterozygosis between Hb-C and beta-thalassemia].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Mar-15, Volume: 49, Issue:9

    Topics: Adult; Blood Protein Electrophoresis; Carbon Radioisotopes; Chromatography, Gel; Female; Hemoglobin C; Heterozygote; Humans; Leucine; Splenomegaly; Thalassemia

1973
Hb K Woolwich the cause of a thalassaemia.
    Nature, 1974, May-31, Volume: 249, Issue:456

    Topics: Amino Acid Sequence; Female; Genes; Genetic Code; Hemoglobins, Abnormal; Heterozygote; Humans; Leucine; Mutation; Pedigree; Reticulocytes; Thalassemia; Tritium; West Indies

1974
Balanced globin chain synthesis in hereditary persistence of fetal hemoglobin.
    The Journal of clinical investigation, 1974, Volume: 54, Issue:2

    Topics: Adult; Alleles; Amino Acids; Anemia, Sickle Cell; Black People; Blood Protein Electrophoresis; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Chromatography; Female; Fetal Hemoglobin; Genotype; Globins; Heterozygote; Humans; Immunoglobulin Fragments; Leucine; Male; Middle Aged; Pedigree; Pregnancy; Reticulocytes; Thalassemia; Tritium

1974
Unbalanced globin chain synthesis in reticulocytes of sickle cell trait individuals with low concentrations of hemoglobin S.
    Biochemical and biophysical research communications, 1974, Jul-24, Volume: 59, Issue:2

    Topics: Adult; Anemia, Sickle Cell; Blood Protein Electrophoresis; Carbon Radioisotopes; Cellulose; Centrifugation, Density Gradient; Cytosol; Hemoglobins; Hemoglobins, Abnormal; Humans; Leucine; Protein Biosynthesis; Reticulocytes; Thalassemia; Time Factors; Tritium

1974
In vitro synthesis of haemoglobin from Fe59 and leucine-C14 by normal, sickle-cell and thalassaemic immature red cells.
    Acta haematologica, 1967, Volume: 38, Issue:4

    Topics: Anemia, Sickle Cell; Carbon Isotopes; Erythrocytes; Hemoglobins; Humans; In Vitro Techniques; Iron Isotopes; Leucine; Thalassemia

1967
Reticulocyte and normoblast labelling with leucine -3H in thalassaemic and non thalassaemic subjects.
    Acta haematologica, 1968, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Autoradiography; Blood Cell Count; Child; Child, Preschool; Electrophoresis; Female; Hemoglobins; Humans; Infant; Leucine; Male; Middle Aged; Reticulocytes; Thalassemia; Tritium

1968
Bone marrow and peripheral blood globin synthesis in an American black family with beta thalassemia.
    Blood, 1972, Volume: 39, Issue:6

    Topics: Black People; Bone Marrow; Carbon Isotopes; Cells, Cultured; Child; Chromatography; Erythropoiesis; Female; Globins; Heterozygote; Homozygote; Humans; Leucine; Thalassemia; White People

1972
Equal synthesis of - and -globin chains in erythroid precursors in heterozygous -thalassemia.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:7

    Topics: Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Centrifugation, Density Gradient; Globins; Heterozygote; Humans; Leucine; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Reticulocytes; Ribosomes; Thalassemia

1972
Globin chain synthesis in the marrow and reticulocytes of beta thalassemia, hemoglobin H disease, and beta delta thalassemia.
    Blood, 1972, Volume: 40, Issue:1

    Topics: Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Chromatography; Globins; Hemoglobinometry; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Leucine; Reticulocytes; Thalassemia; Valine

1972
Gamma-beta thalassemia: a cause of hemolytic disease of the newborn.
    The New England journal of medicine, 1972, Jan-20, Volume: 286, Issue:3

    Topics: Anemia, Hemolytic, Congenital; Anemia, Hypochromic; Carbon Isotopes; Chromatography; Erythroblastosis, Fetal; Erythrocyte Count; Erythrocytes, Abnormal; Female; Fetal Hemoglobin; Globins; Hematocrit; Hemoglobinometry; Humans; Infant; Infant, Newborn; Leucine; Male; Pedigree; Pregnancy; Reticulocytes; Thalassemia

1972
Delta-beta-thalassaemia in a Chinese family.
    British journal of haematology, 1972, Volume: 23, Issue:4

    Topics: Adult; Alanine; Asian People; Black People; Carbon Isotopes; Child; Child, Preschool; Chromatography; Female; Fetal Hemoglobin; Glycine; Hemoglobinopathies; Heterozygote; Humans; Infant; Leucine; Male; Middle Aged; Pedigree; Peptides; Reticulocytes; Thalassemia

1972
Hemoglobin Lepore trait: globin synthesis in bone marrow and peripheral blood.
    Science (New York, N.Y.), 1972, Nov-10, Volume: 178, Issue:4061

    Topics: Bone Marrow; Carbon Isotopes; Chromatography; Globins; Hemoglobinopathies; Humans; Leucine; Thalassemia

1972
Isolation and translation of hemoglobin messenger RNA from thalassemia, sickle cell anemia, and normal human reticulocytes.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:11

    Topics: Anemia, Sickle Cell; Animals; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chromatography; Globins; Hemoglobins; Hemoglobins, Abnormal; Humans; Leucine; Methylcellulose; Peptide Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Thalassemia

1971
Disordered globin synthesis in thalassemia.
    Annals of the New York Academy of Sciences, 1969, Nov-20, Volume: 165, Issue:1

    Topics: Blood Proteins; Chromatography; Globins; Humans; Leucine; Peptides; Reticulocytes; Thalassemia; Tritium

1969
Unbalanced globin chain synthesis in alpha-thalassemia heterozygotes.
    Annals of the New York Academy of Sciences, 1969, Nov-20, Volume: 165, Issue:1

    Topics: Asian People; Blood Proteins; Carbon Isotopes; Female; Globins; Heterozygote; Humans; Leucine; Male; Pedigree; Thalassemia; White People

1969
Hemoglobin synthesis during erythroid cell development in thalassemia and other hemolytic anemias.
    Annals of the New York Academy of Sciences, 1969, Nov-20, Volume: 165, Issue:1

    Topics: Anemia, Hemolytic; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Chromatography; Erythrocytes; Fetal Hemoglobin; Hemoglobins; Humans; Leucine; Mercaptoethanol; Reticulocytes; Spectrophotometry; Thalassemia; Tritium; Valine

1969
Cell-free hemoglobin synthesis in beta-thalassemia.
    Proceedings of the National Academy of Sciences of the United States of America, 1970, Volume: 67, Issue:4

    Topics: Anemia, Hemolytic, Autoimmune; Anemia, Sickle Cell; Animals; Carbon Isotopes; Cell-Free System; Chromatography; Hemoglobins; Humans; In Vitro Techniques; Leucine; Lysine; Methylcellulose; Rabbits; Reticulocytes; Ribosomes; Thalassemia; Tritium

1970
Haemoglobin synthesis in beta-thalassaemia.
    British journal of haematology, 1969, Volume: 17, Issue:5

    Topics: Alanine; Blood Protein Electrophoresis; Chromatography; Chromatography, Gel; Hemoglobins; Humans; In Vitro Techniques; Leucine; Molecular Weight; Thalassemia; Tritium; Valine

1969
The silent carrier of beta thalassemia.
    The New England journal of medicine, 1969, Dec-11, Volume: 281, Issue:24

    Topics: Adult; Albania; Bone Marrow Examination; Carbon Isotopes; Child; Chromatography; Erythrocyte Count; Erythrocytes; Female; Fetal Hemoglobin; Globins; Hemoglobinometry; Hemoglobins; Heterozygote; Humans; Hyperplasia; Leucine; Male; Middle Aged; Osmotic Fragility; Pedigree; Pennsylvania; Reticulocytes; Thalassemia

1969
Heterozygous beta thalassemia: balanced globin synthesis in bone marrow cells.
    Science (New York, N.Y.), 1970, Mar-13, Volume: 167, Issue:3924

    Topics: Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Erythrocytes; Hemoglobins; Heterozygote; Humans; Kinetics; Leucine; Reticulocytes; RNA, Messenger; Thalassemia

1970
Mild thalassemia: the result of interactions of alpha and beta thalassemia genes.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:4

    Topics: Adult; Bone Marrow; Carbon Isotopes; Chromatography; Erythrocyte Count; Genes; Genotype; Hemoglobinometry; Hemoglobins; Hemolysis; Humans; Leucine; Male; Pedigree; Reticulocytes; Thalassemia

1970
Beta thalassemia trait: detection at birth.
    Science (New York, N.Y.), 1968, Aug-09, Volume: 161, Issue:3841

    Topics: Birth Weight; Carbon Isotopes; Chromatography, Ion Exchange; Gestational Age; Hemoglobins, Abnormal; Heterozygote; Humans; Infant, Newborn; Leucine; Methylcellulose; Molecular Biology; Peptide Biosynthesis; Thalassemia; Umbilical Cord

1968
Excess of alpha-globin synthesis in homozygous beta-thalassemia. Its cytoplasmic molecular forms.
    European journal of biochemistry, 1968, Volume: 5, Issue:3

    Topics: Adult; Blood Proteins; Centrifugation, Density Gradient; Child; Child, Preschool; Chromatography, Ion Exchange; Cytoplasm; Erythrocytes; Globins; Heme; Hemoglobins; Hemolysis; Homozygote; Humans; Infant, Newborn; Infant, Premature; Leucine; Lysine; Peptides; Thalassemia; Tritium; Valine

1968
Haemoglobin synthesis in beta-thalassaemia.
    Nature, 1968, Nov-16, Volume: 220, Issue:5168

    Topics: Carbon Isotopes; Chromatography, Ion Exchange; Genetic Code; Hemoglobins, Abnormal; Humans; Leucine; Methylcellulose; Peptide Biosynthesis; Peptides; Reticulocytes; Ribosomes; RNA, Messenger; Thalassemia; Tritium

1968
Globin chain synthesis in the alpha thalassemia syndromes.
    The Journal of clinical investigation, 1969, Volume: 47, Issue:11

    Topics: Anemia, Hypochromic; Blood Protein Electrophoresis; Blood Proteins; Carbon Isotopes; Erythrocyte Count; Globins; Hematocrit; Hemoglobinopathies; Hemoglobins; Humans; Leucine; Lymphatic Diseases; Pedigree; Reticulocytes; Thalassemia

1969
Intracellular loss of free alpha chains in beta thalassemia.
    Nature, 1969, Apr-19, Volume: 222, Issue:5190

    Topics: Anemia, Hemolytic; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Erythrocytes; Globins; Hemoglobins, Abnormal; Humans; Leucine; Peptides; Thalassemia

1969
The pattern of disordered haemoglobin synthesis in homozygous and heterozygous beta-thalassaemia.
    British journal of haematology, 1969, Volume: 16, Issue:3

    Topics: Anemia, Sickle Cell; Carbon Isotopes; Cellulose; Chromatography; Chromatography, Gel; Culture Techniques; Dextrans; Hemoglobins; Hemoglobins, Abnormal; Heterozygote; Homozygote; Humans; Iron Isotopes; Leucine; Molecular Biology; Reticulocytes; Thalassemia; Tritium

1969
Unequal synthesis of complementary globin chains of human fetal hemoglobin by the effect of L-O-methylthreonine.
    The Journal of biological chemistry, 1969, Apr-25, Volume: 244, Issue:8

    Topics: Blood Proteins; Carbon Isotopes; Chromatography, Gel; Complement System Proteins; Depression, Chemical; Erythroblastosis, Fetal; Female; Fetal Hemoglobin; Globins; Heme; Hemolysis; Humans; In Vitro Techniques; Infant, Newborn; Isoleucine; Leucine; Lysine; Peptide Biosynthesis; Pregnancy; Solubility; Thalassemia; Threonine

1969
Asymmetrical incorporation of amino acids in the alpha and beta chains of hemoglobin synthesized by thalassemic reticulocytes.
    The Journal of laboratory and clinical medicine, 1965, Volume: 66, Issue:3

    Topics: Anemia, Sickle Cell; Dinitrophenols; Hemoglobins; Humans; In Vitro Techniques; Leucine; Leukemia, Lymphoid; Peptide Biosynthesis; Reticulocytes; Thalassemia; Valine

1965
Globin synthesis in thalassaemia: an in vitro study.
    Nature, 1965, Dec-11, Volume: 208, Issue:5015

    Topics: Carbon Isotopes; Globins; Hemoglobins; Humans; In Vitro Techniques; Leucine; Reticulocytes; Spherocytosis, Hereditary; Thalassemia

1965