leucine has been researched along with Skin Neoplasms in 41 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 30 (73.17) | 18.7374 |
1990's | 2 (4.88) | 18.2507 |
2000's | 3 (7.32) | 29.6817 |
2010's | 4 (9.76) | 24.3611 |
2020's | 2 (4.88) | 2.80 |
Authors | Studies |
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Chen, Y; He, X; Hu, H; Huang, W; Li, B; Li, Y; Liu, J; Liu, W; Peng, Z; Tan, L; Yan, SM; Yu, F; Yuan, Y; Zhang, H; Zhang, Y | 1 |
Dong, Z; Huang, L; Jiang, Y; Li, J; Liu, K; Yao, K; Zhao, S | 1 |
Allegra, M; Bahadoran, P; Ballotti, R; Giacchero, D; Hofman, P; Lacour, JP; Le Duff, F; Long-Mira, E; Passeron, T | 1 |
Bailey, CG; Beaumont, KA; Font, J; Haass, NK; Holst, J; Jormakka, M; Otte, NJ; Rasko, JE; Ryan, RM; Sharp, DM; Tiffen, JC; van Geldermalsen, M; Wang, Q | 1 |
Alaibac, M; Frigo, AC; Michelotto, A; Piaserico, S | 1 |
Diaz-Meco, MT | 1 |
Bosserhoff, A; Dennhöfer, R; Hunzelmann, N; Klose, A; Krieg, T; Kurschat, P; Mauch, C; van Muijen, G; Zigrino, P | 1 |
ISHIKAWA, H; KLINGMUELLER, G | 1 |
DOERMER, P; LESCH, R; OEHLERT, W | 1 |
BADEN, HP; PEARLMAN, C | 1 |
Aozuka, Y; Koizumi, K; Saiki, I; Saitoh, Y; Sakurai, H; Ueda, Y | 1 |
Bhisey, RA; Ramchandani, AG; Sirsat, SM | 1 |
Bolmer, SD; Wolf, G | 1 |
Ikeda, S; Miyasato, H; Saito, K; Tajima, K | 1 |
Hayasaka, K; Ikeda, S; Ishihara, K; Jimbow, K; Kukita, A; Seki, Y; Takahashi, H; Terakado, T | 1 |
Amirkhan, RH; Frederick, GD; Friedberg, EC; Schultz, RA | 1 |
Arden, KC; Cavenee, WK; Gutzmer, R; Herbst, RA; Kapp, A; Matiaske, F; Mommert, S; Weiss, J | 1 |
Bogyo, M; Burlingame, A; Greenbaum, D; Medzihradszky, KF | 1 |
Lupulescu, A | 1 |
Boutwell, RK; Bowden, GT; Slaga, TJ | 1 |
Hayasaka, K; Ishihara, K; Yamazaki, N | 1 |
Ikeda, S; Ishihara, K; Taguchi, G | 2 |
Alvord, G; Bizub, D; Blair, D; Skalka, AM | 1 |
Alidina, R; Epstein, JH; Fukuyama, K; Kashima, M; Kikuchi, M | 1 |
Esumi, H; Ikeda, S; Suzuki, T; Tomita, Y | 1 |
Hopsu-Havu, VK; Järvinen, M | 1 |
Balda, BR; Birkmayer, GD | 1 |
Scribner, JD; Slaga, TJ | 1 |
Boutwell, RK; Bowden, GT; Shapas, BG; Slaga, TJ | 2 |
Burdzy, K; Raick, AN | 1 |
Hozumi, M; Ogawa, M; Sugimura, T; Takeuchi, T; Umezawa, H | 1 |
da Fonseca-Wollheim, F; Liss, E; Reinecke, A | 1 |
Jackisch, R; Meier-Gerwert, H; Weitzel, G; Zinser, D | 1 |
Baird, WM; Boutwell, RK; Sedgwick, JA | 1 |
Bates, RR; Gelboin, HV; Klein, M | 1 |
Beasley, AR; Dietrich, LS; López, DM; Sigel, MM | 1 |
Hu, F; Kitano, Y | 1 |
Boutwell, RK; Hennings, H | 1 |
Kinzel, V; Maurer, R; Süss, R; Volm, M | 1 |
3 trial(s) available for leucine and Skin Neoplasms
Article | Year |
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[Phase III controlled studies of bestatin in malignant tumors of the skin--results of treatment of squamous cell carcinoma and genital Paget's disease].
Topics: Aged; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Administration Schedule; Female; Genital Neoplasms, Female; Genital Neoplasms, Male; Humans; Leucine; Male; Middle Aged; Paget Disease, Extramammary; Skin Neoplasms | 1985 |
[Phase III study of bestatin in patients with malignant skin tumors. (1) Malignant melanoma].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Leucine; Lymph Node Excision; Male; Melanoma; Middle Aged; Prognosis; Skin Neoplasms | 1985 |
[Multidisciplinary treatment of malignant melanoma].
Topics: Adult; Aged; Female; Humans; Leucine; Lymph Node Excision; Male; Melanoma; Middle Aged; Neoplasm Staging; Picibanil; Prognosis; Sex Factors; Skin Neoplasms | 1985 |
38 other study(ies) available for leucine and Skin Neoplasms
Article | Year |
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Amino acids and RagD potentiate mTORC1 activation in CD8
Topics: Animals; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Enzyme Activation; HEK293 Cells; Homeodomain Proteins; Humans; Leucine; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Mechanistic Target of Rapamycin Complex 1; Melanoma, Experimental; Mice, Inbred C57BL; Mice, Knockout; Monomeric GTP-Binding Proteins; Phenotype; Signal Transduction; Skin Neoplasms; Tumor Escape; Tumor Microenvironment | 2021 |
Bestatin Cream Impairs Solar Simulated Light‒Driven Skin Inflammation and Skin Carcinogenesis in Mice.
Topics: Animals; Apoptosis; Carcinogenesis; Cells, Cultured; Dermatitis; Epoxide Hydrolases; Humans; Leucine; Mice; Mice, Inbred BALB C; Neoplasms, Radiation-Induced; Ointments; Receptors, Leukotriene B4; Skin Neoplasms; Sunlight; Transcription Factor RelA | 2021 |
Major clinical response to a BRAF inhibitor in a patient with a BRAF L597R-mutated melanoma.
Topics: Aged; Antineoplastic Agents; Arginine; Back; Cell Survival; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Imidazoles; Indoles; Leucine; Lung Neoplasms; MAP Kinase Signaling System; Melanoma; Niacinamide; Oximes; Phenylurea Compounds; Point Mutation; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Sorafenib; Sulfonamides; Vemurafenib | 2013 |
Targeting glutamine transport to suppress melanoma cell growth.
Topics: Amino Acid Transport System ASC; Amino Acids, Cyclic; Benzyl Compounds; Biological Transport; Carrier Proteins; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Glutamine; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Mechanistic Target of Rapamycin Complex 1; Melanoma; Minor Histocompatibility Antigens; Multiprotein Complexes; Proto-Oncogene Proteins B-raf; RNA Interference; RNA, Small Interfering; Serine; Signal Transduction; Skin Neoplasms; Spheroids, Cellular; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Ubiquitin-Conjugating Enzymes | 2014 |
TLR7 Gln11Leu single nucleotide polymorphism and response to treatment with imiquimod in patients with basal cell carcinoma: a pilot study.
Topics: Aminoquinolines; Antineoplastic Agents; Carcinoma, Basal Cell; Drug Resistance, Neoplasm; Female; Glutamine; Humans; Imiquimod; Leucine; Male; Pilot Projects; Polymorphism, Single Nucleotide; Skin Neoplasms; Toll-Like Receptor 7; Treatment Outcome | 2015 |
Targeting leucine addiction and autophagy in melanoma.
Topics: Animals; Apoptosis; Autophagy; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Melanocytes; Melanoma; Mice; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Multiprotein Complexes; Proteins; ras Proteins; Signal Transduction; Skin Neoplasms; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2011 |
Invasion of melanoma cells into dermal connective tissue in vitro: evidence for an important role of cysteine proteases.
Topics: Cathepsins; Connective Tissue; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dermis; Extracellular Matrix; Humans; In Vitro Techniques; Leucine; Leupeptins; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Melanoma; Neoplasm Invasiveness; Protease Inhibitors; Skin Neoplasms; Tumor Cells, Cultured | 2003 |
[CAPILLARY VISUALIZATION IN THE PAPILLARY BODY, ESPECIALLY IN PSORIASIS VULGARIS, BY MEANS OF THE LEUCINE-AMINOPEPTIDASE REACTION].
Topics: Aminopeptidases; Animals; Capillaries; Coloring Agents; Eczema; Fibroma; Guinea Pigs; Histocytochemistry; Histological Techniques; Leucine; Leucyl Aminopeptidase; Neurofibromatoses; Psoriasis; Research; Skin; Skin Neoplasms; Staining and Labeling; Tattooing | 1963 |
[AUTORADIOGRAPHIC STUDIES ON DNA SYNTHESIS IN BIOPSY TUMOR TISSUE IN MAN].
Topics: Autoradiography; Biopsy; Bronchial Neoplasms; DNA; DNA, Neoplasm; Humans; Laryngeal Neoplasms; Leucine; Male; Neoplasms; Paranasal Sinus Neoplasms; Research; Skin Neoplasms; Tongue Neoplasms; Tritium | 1963 |
STUDIES OF EPIDERMAL PROTEIN METABOLISM. 3. PROTEIN SYNTHESIS IN AN EPIDERMAL CARCINOMA IN VIVO AND IN VITRO.
Topics: Carbon Isotopes; Cricetinae; Histological Techniques; In Vitro Techniques; Leucine; Liver; Magnesium; Microsomes; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Pharmacology; Phenylalanine; Proteins; Research; Ribosomes; Skin Neoplasms; Uracil Nucleotides | 1965 |
Anti-tumor angiogenesis effect of aminopeptidase inhibitor bestatin against B16-BL6 melanoma cells orthotopically implanted into syngeneic mice.
Topics: Animals; Endothelial Cells; Female; Leucine; Melanoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Neovascularization, Pathologic; Protease Inhibitors; Skin Neoplasms; Transplantation, Heterologous; Umbilical Veins | 2004 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on the incorporation of labelled precursors into RNA, DNA and protein in epidermis, dermis and subcutis from precancerous mouse skin with reference to enhanced tumorigenesis.
Topics: Animals; Carbon Radioisotopes; DNA Replication; Female; Kinetics; Leucine; Mice; Phorbols; Precancerous Conditions; Protein Biosynthesis; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymidine; Transcription, Genetic; Tritium; Uridine | 1984 |
Stimulation of fibronectin production by retinoic acid in mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromatography, Affinity; Female; Fibronectins; Fucose; Leucine; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
[Phase I study of Bestatin: (I) A clinical study on determination of an optimal dose of Bestatin].
Topics: Adjuvants, Immunologic; Adolescent; Adult; Antibiotics, Antineoplastic; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leucine; Male; Middle Aged; Skin Neoplasms | 1983 |
[Malignant melanoma in Japan: unique distribution and effect of DAV chemoimmunotherapy].
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Drug Therapy, Combination; Female; Humans; Leucine; Male; Melanoma; Middle Aged; Nimustine; Nitrosourea Compounds; Picibanil; Proteoglycans; Skin Neoplasms; Vincristine | 1982 |
Structural and mutational analysis of the xeroderma pigmentosum group D (XPD) gene.
Topics: Alleles; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cell Survival; Cloning, Molecular; DNA; DNA Helicases; DNA Mutational Analysis; DNA Primers; DNA Repair; DNA-Binding Proteins; Exons; Fishes; Genes, Recessive; Humans; Leucine; Mice; Molecular Sequence Data; Plasmids; Point Mutation; Polymerase Chain Reaction; Proteins; Saccharomyces cerevisiae; Schizosaccharomyces; Sequence Homology, Amino Acid; Skin Neoplasms; Transcription Factors; Ultraviolet Rays; Valine; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group D Protein | 1994 |
Further evidence for ultraviolet light induction of CDKN2 (p16INK4) mutations in sporadic melanoma in vivo.
Topics: Alanine; Alleles; Arginine; Carrier Proteins; Cyclin-Dependent Kinase Inhibitor p16; DNA, Neoplasm; Enzyme Inhibitors; Exons; Heterozygote; Humans; Leucine; Melanoma; Mutation; Polymerase Chain Reaction; Skin; Skin Neoplasms; Ultraviolet Rays; Valine | 1997 |
Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools.
Topics: Affinity Labels; Animals; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dendritic Cells; Disease Progression; Epoxy Compounds; Gene Expression Regulation, Enzymologic; Kidney; Leucine; Mice; Molecular Probes; Neoplasm Proteins; Organ Specificity; Peptide Library; Peptides; Rats; Skin Neoplasms; Substrate Specificity; Tumor Cells, Cultured | 2000 |
Enhancement of carcinogenesis by prostaglandins in male albino Swiss mice.
Topics: Animals; Carcinoma, Squamous Cell; Hyperplasia; Leucine; Male; Methylcholanthrene; Mice; Microscopy, Electron; Neoplasms, Experimental; Papilloma; Prostaglandins E, Synthetic; Prostaglandins F, Synthetic; Skin Neoplasms; Thymidine; Uridine | 1978 |
Acetic acid, a potent stimulator of mouse epidermal macromolecular synthesis and hyperplasia but with weak tumor-promoting ability.
Topics: Acetates; Animals; Croton Oil; Cytidine; DNA; Dose-Response Relationship, Drug; Female; Hyperplasia; Leucine; Mice; Neoplasms, Experimental; Papilloma; Proteins; RNA; Skin; Skin Neoplasms; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thymidine | 1975 |
Current status of melanoma treatment with interferon, cytokines and other biologic response modifiers in Japan.
Topics: Biological Factors; Biological Products; Cell Wall Skeleton; Cytokines; DNA, Bacterial; Glycine; Humans; Interferon Type I; Interferon-gamma; Interferons; Interleukin-2; Leucine; Male; Melanoma; Middle Aged; Mucoproteins; Mycolic Acids; Picibanil; Recombinant Proteins; Skin Neoplasms; Tumor Necrosis Factor-alpha | 1989 |
Correlation between H-ras p21TLeu61 protein content and tumorigenicity of NIH3T3 cells.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Codon; DNA, Neoplasm; Genes, ras; Leucine; Methionine; Mice; Mice, Nude; Mutation; Oncogene Protein p21(ras); Skin Neoplasms; Transfection | 1988 |
Cysteine protease and its inhibitor in experimentally produced squamous cell carcinomas in hairless mouse skin.
Topics: Animals; Carcinoma, Squamous Cell; Cathepsin H; Cathepsins; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Hydrogen-Ion Concentration; Hydrolysis; Leucine; Mice; Mice, Hairless; Protease Inhibitors; Skin Neoplasms | 1988 |
Aminopeptidase activity of elastotic fibres--a histochemical artifact?
Topics: Aged; Amides; Aminopeptidases; Animals; Azo Compounds; Dialysis; Fibroma; Histocytochemistry; Humans; Kidney; Leucine; Naphthalenes; Rats; Skin; Skin Neoplasms; Staining and Labeling | 1971 |
[Metabolism of malignant melanomas. Biochemical studies].
Topics: Adenosine Triphosphatases; Animals; Carbon Isotopes; Cricetinae; DNA, Neoplasm; Electron Transport Complex IV; Isoleucine; Leucine; Melanoma; Mitochondria; Neoplasms, Experimental; Phenylalanine; Skin Neoplasms | 1972 |
Multiple effects of dexamethasone on protein synthesis and hyperplasia caused by a tumor promoter.
Topics: Alcohols; Animals; Benz(a)Anthracenes; Carcinogens; Cytidine; Cytosol; Depression, Chemical; Dexamethasone; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Female; Hyperplasia; Leucine; Mice; Mice, Inbred Strains; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Proteins; RNA, Neoplasm; Skin; Skin Neoplasms; Spectrophotometry; Terpenes; Thymidine | 1973 |
Macromolecular synthesis following a single application of alkylating agents used as initiators of mouse skin tumorigenesis.
Topics: Alkylating Agents; Animals; Croton Oil; Cytidine; DNA; Female; Hyperplasia; Leucine; Mice; Neoplasms, Experimental; Papilloma; Protein Biosynthesis; RNA; Skin; Skin Neoplasms; Thymidine; Time Factors; Tritium; Urethane | 1973 |
Ultrastructural and biochemical changes induced in mouse epidermis by a hyperplastic agent, ethylphenylpropiolate.
Topics: Animals; Cell Differentiation; Cell Division; Cell Nucleolus; Chromatin; Cytoplasm; DNA; Endoplasmic Reticulum; Female; Golgi Apparatus; Hyperplasia; Leucine; Mice; Microscopy, Electron; Mitochondria; Mitosis; Necrosis; Orotic Acid; Phenylpropionates; Polyribosomes; Protein Biosynthesis; RNA; Skin; Skin Neoplasms; Thymidine; Time Factors; Tritium | 1973 |
Macromolecular synthesis following a single application of polycyclic hydrocarbons used as initiators of mouse skin tumorigenesis.
Topics: Acetates; Animals; Benz(a)Anthracenes; Cytidine; Depression, Chemical; DNA; DNA, Neoplasm; Leucine; Mice; Neoplasm Proteins; Neoplasms, Experimental; Precancerous Conditions; Protein Biosynthesis; RNA; RNA, Neoplasm; Skin Neoplasms; Stimulation, Chemical; Thymidine; Time Factors; Tritium | 1974 |
Inhibition of tumorigenesis in mouse skin by leupeptin, a protease inhibitor from Actinomycetes.
Topics: Acetates; Actinomycetales; Animals; Antineoplastic Agents; Arginine; Benz(a)Anthracenes; Cell Fractionation; Croton Oil; Dimethyl Sulfoxide; Esterases; Female; Leucine; Methods; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Peptides; Propionates; Protease Inhibitors; Skin; Skin Neoplasms; Time Factors; Tosyl Compounds | 1972 |
[Effect of glutamine on the incorporation of ( 14 C)leucine into protein and of ( 3 H)thymidine into DNA of Yoshida ascites tumor cells].
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Cell Line; DNA, Neoplasm; Female; Glutamine; Leucine; Mice; Mice, Inbred Strains; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm; Sarcoma, Yoshida; Skin Neoplasms; Thymidine; Time Factors; Tritium | 1972 |
[Additional classes of tumor inhibiting compounds. V. Cytostatic properties of alkylated alcohols and aldehydes of the chain length C 8 ].
Topics: Alcohol Oxidoreductases; Alcohols; Aldehydes; Alkylation; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Leucine; Mice; Neoplasms, Experimental; Sarcoma, Yoshida; Skin Neoplasms; Thymidine; Tritium; Uridine | 1972 |
Effects of phorbol and four diesters of phorbol on the incorporation of tritiated precursors into DNA, RNA, and protein in mouse epidermis.
Topics: Acetates; Animals; Autoradiography; Carcinogens; Cytidine; DNA; Esters; Fatty Acids; Female; Leucine; Mice; Protein Biosynthesis; Proteins; RNA; Skin; Skin Neoplasms; Stimulation, Chemical; Terpenes; Thymidine; Tritium | 1971 |
Inhibition of mouse skin tumorigenesis by actinomycin D.
Topics: Animals; Benz(a)Anthracenes; Croton Oil; Dactinomycin; In Vitro Techniques; Leucine; Mice; Neoplasms, Experimental; Protein Biosynthesis; Puromycin; Radiometry; Skin Neoplasms; Tritium; Urethane; Uridine | 1965 |
Biochemical and morphologic studies of lymphocystis disease.
Topics: Adenine; Animal Diseases; Animals; Carbon Isotopes; Culture Techniques; DNA; Fish Diseases; Fishes; Hypertrophy; Leucine; Nucleosides; Papilloma; Protein Biosynthesis; RNA; Skin; Skin Neoplasms; Tritium; Virus Diseases; Virus Replication | 1969 |
DNA, RNA, and protein synthesis of pigment cells in culture.
Topics: Animals; Autoradiography; Chromatophores; Culture Techniques; DNA; Leucine; Melanins; Melanoma; Mice; Neoplasms, Experimental; Pigmentation; Protein Biosynthesis; Puromycin; RNA; Skin; Skin Neoplasms; Thymidine; Tritium; Tyrosine; Uridine | 1970 |
Studies on the mechanism of skin tumor promotion.
Topics: Animals; Benzofurans; Croton Oil; DNA, Neoplasm; Female; Leucine; Macromolecular Substances; Mice; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Papilloma; RNA, Neoplasm; Skin; Skin Neoplasms; Thymidine; Tritium; Wound Healing | 1970 |
Carcinogensis and inhibited biosynthesis of soluble mouse skin proteins by actidione.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Cycloheximide; Depression, Chemical; Leucine; Mice; Neoplasms, Experimental; Papilloma; Protein Binding; Protein Biosynthesis; Skin; Skin Neoplasms | 1969 |