leucine has been researched along with Pancreatic Neoplasms in 89 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 72 (80.90) | 18.7374 |
1990's | 5 (5.62) | 18.2507 |
2000's | 4 (4.49) | 29.6817 |
2010's | 7 (7.87) | 24.3611 |
2020's | 1 (1.12) | 2.80 |
Authors | Studies |
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Alves, TC; Bork, U; Chavakis, T; Distler, M; Funk, AM; Jonas, S; Kahlert, C; Komorek, F; Meisterfeld, R; Menschikowski, M; Mirtschink, P; Seifert, AM; Seifert, L; Tritchkova, G; von Bechtolsheim, F; von Renesse, J; Weitz, J | 1 |
He, X; Wang, L; Wang, S; Yuan, Y; Zhang, Y; Zhong, J; Zhou, Y | 1 |
Jain, N; Katoch, P; Mehta, PP; Ray, A | 1 |
Asaoka, T; Doki, Y; Eguchi, H; Fujimoto, M; Gotoh, K; Iwagami, Y; Kobayashi, S; Mori, M; Naka, T; Noda, T; Otsuru, T; Serada, S; Takahashi, T; Wada, H; Yamada, D | 1 |
Buchberger, A; Frost, D; Hao, L; Johnson, J; Kao, WJ; Li, L; Lietz, CB | 1 |
Cui, B; Gao, L; Guan, Q; Guo, H; Sun, N; Tian, L; Wang, L; Zhang, X; Zhao, J | 1 |
Bouvet, M; Hayashi, K; Hoffman, RM; Nagakura, C; Tomita, K; Tsuchiya, H; Yamamoto, N; Yamauchi, K; Zhao, M | 1 |
Dalrymple, SA; Elie, BT; Gocheva, V; Holsinger, LJ; Joyce, JA; Shree, T | 1 |
Bonner, C; Byrne, MM; Farrelly, AM; Kilbride, SM; Prehn, JH | 1 |
Anzai, N; Endou, H; Hayashi, K; Jutabha, P | 1 |
GOLDBARG, JA; PINEDA, EP; RUTENBURG, AM | 1 |
FISCHL, J; PRUZANSKI, W | 2 |
FLANAGAN, GC; RYAN, WG; SCHWARTZ, TB | 1 |
MARKS, V; MARRACK, D; ROSE, FC | 1 |
ARST, HE; DELP, M; MANNING, RT | 1 |
TAKAMORI, M | 1 |
GOLDNER, MG; WEISENFELD, S | 1 |
BRADHAM, R; BUSE, J; BUSE, MG; MARSHALL, JN; OBERMAN, H | 1 |
BARDAWILL, C; CHANG, C | 1 |
EVERSOLE, JW; MOSELEY, T | 1 |
CAMMAROTA, HE | 1 |
GUTH, PH | 1 |
ANAGNOSTOU, E; HADZIYANNIS, S; KAKARI, S; MERICAS, G | 1 |
BOUMAN, PR | 1 |
GRANN, V; MAHLER, RJ; PURDY, R | 1 |
SCHOLTZ, DA | 1 |
AOYAMA, S | 1 |
CHIAPPA, A; PANNELLA, A | 2 |
FIELD, JB | 1 |
CONN, JW; FAJANS, SS; FLOYD, JC; KNOPF, RF | 1 |
FAJANS, SS | 1 |
KLEIN, R; MARKS, JF | 1 |
OVERSTREET, AE; RUPP, JJ | 1 |
Hedeskov, CJ; Knudsen, P; Kofod, H; Lernmark, A | 1 |
Chick, WL; Gishizky, ML; Gold, G; Grodsky, GM | 1 |
Reddy, JK; Warren, JR | 1 |
Battezzati, A; Bianchi, E; Di Carlo, V; Luzi, L; Perseghin, G; Pozza, G; Terruzzi, I | 1 |
Bakker, A; Finkelstein, SD; Keller, G; Pricolo, VE; Przygodzki, R; Sayegh, R; Swalsky, PA | 1 |
Sandler, S; Welsh, N | 1 |
Barazzoni, R; Tessari, P; Tiengo, A; Zanetti, M | 1 |
Flatt, PR; McClenaghan, NH | 1 |
Chiba, T; Itoh, Y; Kajita, M; Kinoh, H; Mori, H; Okada, A; Seiki, M | 1 |
Berger, H | 1 |
Araki, N; Harano, Y; Hoshi, M; Kohama, M; Sakamoto, A | 1 |
Klöppel, G; Seifert, G | 1 |
Hayashi, T; Misugi, Y; Nagai, S; Yamaguchi, H | 1 |
Lundbaek, K; Seyer-Hansen, K | 1 |
Senior, B; Wolfsdorf, JI | 1 |
Chiotellis, E; Dassiou, A; Hadzilouka-Mantaka, A; Koutoulidis, K; Papanicolaou, N; Sawas-Dimopoulou, C; Simitzis, G | 1 |
Fiedorek, FT; Parkinson, D | 1 |
Harty, RF; Jain, DK; McGuigan, JE | 1 |
Barreto, M; Malaisse, WJ; Sener, A; Valverde, I | 1 |
Schonbrunn, A; Sullivan, SJ | 2 |
Archer, MC; Chan, AM; Zucker, PF | 1 |
Ezrin, C; Frohman, LA; Goodman, RS; Kovacs, K; Melmed, S | 1 |
Carrington, CA; Hales, CN; Pearson, EC; Rubery, ED | 1 |
Creutzfeldt, C; Creutzfeldt, W; Track, NS | 1 |
Miles, LE | 1 |
Smith, M | 1 |
Colwell, JA; Furey, WL | 1 |
Frawley, TF; Pensuwan, S | 1 |
Glöckner, E; Knoke, M; Markert, J; Reding, R | 1 |
Sleisenger, MH; Walsh, JH | 1 |
Williams, C | 1 |
Abernethy, RJ; Buchanan, KD; McKiddie, MT | 1 |
DePeyster, FA | 1 |
Brooten, P; Felig, P; Landsberg, L; Sachs, FL | 1 |
Brauman, H; Corvilain, J; Telerman-Toppet, N | 1 |
Grinvalsky, HT; Remigio, PA | 1 |
Parmentier, J; Rubay, J | 1 |
Schwartz, JF; Zwiren, GT | 1 |
Marks, V | 1 |
Corredor, DG; Danowski, TS; Dhawer, VP; Gonzalez, AR; Jung, Y; Khurana, RC; Klayton, R; Sieracki, JC | 1 |
Lindall, AW; Sorenson, RL; Steffes, MW; Wong, ET | 1 |
Baker, L; Balsam, MJ; Bishop, HC; Hummeler, K; Kaye, R; Yakovac, WC | 1 |
Birchard, E; Cameron, GS; Cole, FM; Tuttle, RJ; Wright, AD | 1 |
Levey, GS; Mintz, DH; Schmidt, WM | 1 |
Fink, G; Gutman, RA; Recant, L; Selawry, H; Shapiro, JR | 1 |
Basoli, A; Carboni, M; De Bernardinis, G; Patrassi, N; Perrotta, G | 1 |
Lefebvre, P; Luyckx, A | 1 |
Ishihara, Y; Kuroda, A; Sato, N; Tajima, Y; Wada, Y | 1 |
Grögler, F; Lucke, C; Mitzkat, HJ | 1 |
Duprey, J; Lubetzki, J | 1 |
Wüstenberg, PW | 1 |
Federspil, G; Frezzato, S; Macrì, C; Muggeo, M; Tiengo, A; Trisotto, A; Vianello, A | 1 |
Brunner, G; Kattermann, R; Sommer, J | 1 |
8 review(s) available for leucine and Pancreatic Neoplasms
Article | Year |
---|---|
[POSSIBILITIES AND LIMITATIONS IN THE DETERMINATION OF INSULIN IN BLOOD IN THE DIAGNOSIS OF HYPERINSULINISM].
Topics: Adenoma, Islet Cell; Blood; Diagnosis; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Leucine; Pancreatic Neoplasms; Tolbutamide | 1963 |
LEUCINE-INDUCED HYPOGLYCEMIA.
Topics: Adenoma, Islet Cell; Amino Acid Metabolism, Inborn Errors; Diagnosis; Humans; Hypoglycemia; Insulin; Leucine; Metabolism; Pancreatic Neoplasms | 1965 |
[Diffuse nesidioblastic island hyperplasia in the juvenile hypoglycemia syndrome].
Topics: Adenoma, Islet Cell; Child; Child, Preschool; Humans; Hyperplasia; Hypoglycemia; Infant; Infant, Newborn; Islets of Langerhans; Leucine; Pancreatic Neoplasms; Syndrome | 1975 |
Hypoglycemia: tolbutamide and leucine tests in insulinoma.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Tolbutamide | 1968 |
Functioning tumors of the pancreas.
Topics: Adenoma, Islet Cell; Diarrhea; Digestive System; Fasting; Gastrins; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Hypokalemia; Leucine; Pancreatic Neoplasms; Tolbutamide; Zollinger-Ellison Syndrome | 1968 |
Progress report. Diagnosis of insulinoma.
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Child; Child, Preschool; Diagnosis, Differential; Ethanol; Fasting; Glucagon; Glucose Tolerance Test; Hormones, Ectopic; Humans; Hypoglycemia; Infant; Infant, Newborn; Injections, Intravenous; Insulin; Leucine; Pancreatic Neoplasms; Parathyroid Neoplasms; Pituitary Neoplasms; Tolbutamide | 1971 |
[Insulinoma].
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Angiography; Child; Diagnosis, Differential; Diagnostic Techniques, Surgical; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Proinsulin; Tolbutamide | 1973 |
[The hypoglycemia syndrome].
Topics: Alloxan; Angiography; Antibiotics, Antineoplastic; Blood Glucose; Diagnosis, Differential; Diazoxide; Diet Therapy; Epinephrine; Gastrointestinal Diseases; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Metabolic Diseases; Neoplasms; Pancreatic Neoplasms; Prednisone; Tolbutamide | 1970 |
81 other study(ies) available for leucine and Pancreatic Neoplasms
Article | Year |
---|---|
Tumour catabolism independent of malnutrition and inflammation in upper GI cancer patients revealed by longitudinal metabolomics.
Topics: 3-Hydroxybutyric Acid; Cachexia; Gastrointestinal Neoplasms; Humans; Inflammation; Leucine; Malnutrition; Metabolomics; Pancreatic Neoplasms | 2023 |
Serum metabolomics differentiating pancreatic cancer from new-onset diabetes.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Biomarkers, Tumor; Body Mass Index; CA-19-9 Antigen; Carcinoma, Pancreatic Ductal; Chromatography, Liquid; Diabetes Mellitus, Type 2; Diagnosis, Differential; Early Detection of Cancer; Feasibility Studies; Female; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Principal Component Analysis; Sensitivity and Specificity; Serologic Tests; Valine | 2017 |
Dileucine-like motifs in the C-terminal tail of connexin32 control its endocytosis and assembly into gap junctions.
Topics: Amino Acid Motifs; Cell Line, Tumor; Cell Polarity; Clathrin; Connexins; Endocytosis; Epithelial Cells; Gap Junction beta-1 Protein; Gap Junctions; Humans; Leucine; Male; Pancreatic Neoplasms; Prostatic Neoplasms | 2018 |
Epithelial-mesenchymal transition via transforming growth factor beta in pancreatic cancer is potentiated by the inflammatory glycoprotein leucine-rich alpha-2 glycoprotein.
Topics: Cadherins; Carcinoma, Pancreatic Ductal; Cell Line; Cell Line, Tumor; Disease-Free Survival; Epithelial-Mesenchymal Transition; Female; Glycoproteins; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Leucine; Male; Neoplasm Recurrence, Local; Pancreatic Neoplasms; Phosphorylation; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1 | 2019 |
Mass Defect-Based N,N-Dimethyl Leucine Labels for Quantitative Proteomics and Amine Metabolomics of Pancreatic Cancer Cells.
Topics: Amines; Cell Line, Tumor; Chromatography, Reverse-Phase; Humans; Leucine; Metabolomics; Methylation; Pancreatic Neoplasms; Proteins; Proteomics; Tandem Mass Spectrometry | 2017 |
AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin secretion under high leucine exposure in rat insulinoma beta-cells.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Death; Cell Line, Tumor; Enzyme Inhibitors; Glucokinase; Glucose Transporter Type 2; Homeodomain Proteins; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Leucine; Pancreatic Neoplasms; Rats; Ribonucleotides; Trans-Activators | 2009 |
Efficacy of a genetically-modified Salmonella typhimurium in an orthotopic human pancreatic cancer in nude mice.
Topics: Animals; Arginine; Cell Line, Tumor; Green Fluorescent Proteins; Humans; Leucine; Mice; Mice, Nude; Mutation; Organisms, Genetically Modified; Pancreatic Neoplasms; Salmonella typhimurium; Transfection; Xenograft Model Antitumor Assays | 2009 |
Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Availability; Cathepsins; Cell Proliferation; Cyclopropanes; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hydrocarbons, Fluorinated; Leucine; Mice; Neoplasm Invasiveness; Neovascularization, Pathologic; Pancreatic Neoplasms; Protease Inhibitors; Sulfones; Tumor Burden | 2010 |
Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Survival; Diabetes Mellitus, Type 1; Gene Expression Regulation; Genes, Dominant; Hepatocyte Nuclear Factor 1-alpha; Insulin-Secreting Cells; Insulinoma; Leucine; Mutation; Pancreatic Neoplasms; Protein Processing, Post-Translational; Rats; Real-Time Polymerase Chain Reaction; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2011 |
c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells.
Topics: Base Sequence; Binding Sites; Cell Line, Tumor; Cell Proliferation; Consensus Sequence; Down-Regulation; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, Reporter; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Luciferases; Pancreatic Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; RNA, Small Interfering | 2012 |
Leucine aminopeptidase activity; observations in patients with cancer of the pancreas and other diseases.
Topics: Encephalomyelitis; Leucine; Leucyl Aminopeptidase; Neoplasms; Pancreas; Pancreatic Neoplasms; Peptide Hydrolases | 1958 |
[Appraisal of serum leucine aminopeptidase activity and its diagnostic value].
Topics: Jaundice; Jaundice, Obstructive; Leucine; Leucyl Aminopeptidase; Pancreatic Neoplasms; Peptide Hydrolases | 1961 |
Studies on patients with islet-cell tumor, including the phenomenon of leucine-induced accentuation of hypoglycemia.
Topics: Adenoma, Islet Cell; Blood Glucose; Humans; Hypoglycemia; Leucine; Pancreatic Neoplasms | 1961 |
A leucine-sensitive insulin-secreting tumour.
Topics: Adenoma, Islet Cell; Humans; Insulin; Leucine; Pancreatic Neoplasms | 1960 |
Serum leucine aminopeptidase activity: findings in carcinoma of the pancreas, pregnancy and other disorders.
Topics: Carcinoma; Leucine; Leucyl Aminopeptidase; Liver Diseases; Pancreas; Pancreatic Neoplasms; Peptide Hydrolases; Pregnancy | 1959 |
[Clinical significance of serum leucine aminopeptidase activity in liver, bile duct, and pancreatic diseases].
Topics: Aminopeptidases; Bile Duct Neoplasms; Bile Ducts; Humans; Leucine; Leucyl Aminopeptidase; Liver Diseases; Pancreas; Pancreatic Diseases; Pancreatic Neoplasms | 1963 |
Hyperinsulinemia in 1-leucine-sensitive hypoglycemia in an adult.
Topics: Adenoma, Islet Cell; Adult; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Medical Records; Pancreatic Neoplasms | 1961 |
FUNCTIONING PANCREATIC ISLET CELL ADENOMA. WITH LEUCINE-INDUCED HYPOGLYCEMIA.
Topics: Adenoma, Islet Cell; Fasting; Humans; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Pathology; Surgical Procedures, Operative; Tolbutamide; Toxicology | 1963 |
SERUM LACTIC DEHYDROGENASE, LEUCINE AMINOPEPTIDASE AND 5-NUCLEOTIDASE ACTIVITIES: OBSERVATION IN PATIENTS WITH CARCINOMA OF THE PANCREAS AND HEPATOBILIARY DISEASE.
Topics: Aminopeptidases; Blood Chemical Analysis; Carcinoma; Carcinoma, Hepatocellular; Cholelithiasis; Clinical Enzyme Tests; Hepatitis; Hepatitis A; Humans; Jaundice; Jaundice, Obstructive; L-Lactate Dehydrogenase; Leucine; Leucyl Aminopeptidase; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Liver Neoplasms; Nucleotidases; Pancreas; Pancreatic Neoplasms; Pancreatitis | 1963 |
ELEVATED SERUM LEUCINE AMINOPEPTIDASE ACTIVITY: CLINICAL SIGNIFICANCE IN PANCREATIC CARCINOMA.
Topics: Aminopeptidases; Clinical Enzyme Tests; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms | 1963 |
[THE LEUCINE AMINOPEPTIDASE. ITS IMPORTANCE IN THE DIAGNOSIS OF BILIARY DISEASES AND IN CASES OF NEOPLASM OF THE HEAD OF THE PANCREAS].
Topics: Aminopeptidases; Blood; Clinical Enzyme Tests; Clinical Laboratory Techniques; Diagnosis, Differential; Jaundice; Jaundice, Obstructive; Leucine; Leucyl Aminopeptidase; Liver Diseases; Neoplasms; Pancreatic Neoplasms | 1963 |
SERUM LEUCINE AMINOPEPTIDASE: SOURCE AND DIAGNOSTIC VALUE.
Topics: Aminopeptidases; Cholelithiasis; Clinical Enzyme Tests; Hepatitis; Hepatitis A; Leucine; Leucyl Aminopeptidase; Liver Cirrhosis; Pancreatic Neoplasms; Pancreatitis | 1963 |
THE DIAGNOSTIC VALUE OF SERUM LEUCINE AMINOPEPTIDASE.
Topics: Adolescent; Aminopeptidases; Chemical and Drug Induced Liver Injury; Child; Cholecystitis; Cholelithiasis; Clinical Enzyme Tests; Gallstones; Geriatrics; Hepatitis; Hepatitis A; Jaundice; Jaundice, Obstructive; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms | 1964 |
FUNCTIONING ISLET CELL ADENOMA.
Topics: Adenoma, Islet Cell; Cerebrovascular Disorders; Diagnosis, Differential; Geriatrics; Humans; Hyperinsulinism; Leucine; Pancreatic Neoplasms; Tolbutamide | 1964 |
SPONTANEOUS HYPOGLYCEMIA: DIAGNOSTIC CONSIDERATIONS AND MANAGEMENT.
Topics: Adenoma, Islet Cell; Diabetes Mellitus; Diagnosis, Differential; Humans; Hypoglycemia; Leucine; Malingering; Neoplasm Metastasis; Pancreatic Neoplasms; Surgical Procedures, Operative; Tolbutamide | 1964 |
[FUNCTIONAL DIAGNOSIS OF PANCREATIC DISORDERS].
Topics: Aminopeptidases; Amylases; Blood Chemical Analysis; Body Fluids; Carbohydrates; Cholecystokinin; Clinical Enzyme Tests; Diagnosis; Gastrointestinal Hormones; Humans; Iodine Isotopes; Leucine; Lipase; Metabolism; Pancreatic Neoplasms; Pancreatitis; Secretin; Triolein; Trypsin; Urine | 1964 |
[IMPORTANCE OF THE DETERMINATION OF SERUM LEUCYL-AMINOPEPTIDASE IN THE DIFFERENTIAL DIAGNOSIS OF JAUNDICES DUE TO STASIS].
Topics: Aminopeptidases; Cholelithiasis; Clinical Enzyme Tests; Diagnosis, Differential; Jaundice; Jaundice, Obstructive; Leucine; Leucyl Aminopeptidase; Pancreatic Neoplasms | 1963 |
[COMPARATIVE STUDY OF THE SIGNIFICANCE WHICH THE DETERMINATION OF SOME ENZYMES HAS FOR THE DIFFERENTIAL DIAGNOSIS OF JAUNDICES DUE TO STASIS].
Topics: Alanine Transaminase; Alkaline Phosphatase; Aminopeptidases; Cholelithiasis; Clinical Enzyme Tests; Diagnosis, Differential; Fructose-Bisphosphate Aldolase; Jaundice; Jaundice, Obstructive; Leucine; Pancreatic Neoplasms | 1963 |
CLINICAL AND BIOCHEMICAL STUDIES IN PATIENTS WITH FUNCTIONING ISLET CELL TUMORS.
Topics: Adenoma, Islet Cell; Amino Acids; Biochemical Phenomena; Biochemistry; Biomedical Research; Carbohydrate Metabolism; Glucose; Glucose Tolerance Test; Glutarates; Humans; Hypoglycemia; Insulin; Isoleucine; Leucine; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Research; Valine | 1964 |
PLASMA INSULIN IN ORGANIC HYPERINSULINISM: COMPARATIVE EFFECTS OF TOLBUTAMIDE, LEUCINE AND GLUCOSE.
Topics: Adenoma, Islet Cell; Blood; Blood Chemical Analysis; Blood Glucose; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Pharmacology; Surgical Procedures, Operative; Tolbutamide | 1964 |
THE EVALUATION OF SERUM LEUCINE-AMINOPEPTIDASE ESTIMATION; THE INFLUENCE OF THE ADMINISTRATION OF STEROIDS ON S-LAP ACTIVITY IN OBSTRUCTIVE DISEASES OF THE BILIARY TRACT. (PRELIMINARY REPORT).
Topics: Alkaline Phosphatase; Biliary Tract; Cholelithiasis; Clinical Enzyme Tests; Drug Therapy; Gallbladder Neoplasms; Humans; Leucine; Leucyl Aminopeptidase; Liver Diseases; Liver Neoplasms; Pancreatic Neoplasms; Prednisone; Surgical Procedures, Operative | 1964 |
Effect of leucine on plasma insulin concentration in a girl with a pancreatic adenoma.
Topics: Adenoma; Female; Humans; Insulin; Leucine; Pancreatic Neoplasms | 1961 |
Functioning islet cell adenoma with a note about leucine sensitivity.
Topics: Adenoma, Islet Cell; Blood Glucose; Humans; Leucine; Medical Records; Pancreatic Neoplasms | 1961 |
L-leucine methyl ester stimulates insulin secretion and islet glutamate dehydrogenase.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Glucagon; Glucose; Glutamate Dehydrogenase; Glutamine; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Leucine; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pancreatic Neoplasms; Rats | 1983 |
Contrasting patterns of insulin biosynthesis, compartmental storage, and secretion. Rat tumor versus islet cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Leucine; Male; Neoplasm Transplantation; Pancreatic Neoplasms; Proinsulin; Rats; Rats, Inbred Strains | 1984 |
Transplantable pancreatic acinar carcinoma.
Topics: Animals; Autoradiography; Biological Transport; Carbachol; Carcinoma; Cytoplasmic Granules; Enzyme Precursors; Leucine; Male; Nafenopin; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Pancreatic Neoplasms; Rats; Rats, Inbred F344; Tritium | 1981 |
Defective insulin action on protein and glucose metabolism during chronic hyperinsulinemia in subjects with benign insulinoma.
Topics: Adult; Blood Glucose; Carbon Radioisotopes; Chronic Disease; Glucose; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Insulinoma; Keto Acids; Leucine; Liver; Middle Aged; Pancreatic Neoplasms; Proteins; Radioisotope Dilution Technique; Reference Values; Tritium | 1995 |
K-ras-2 topographic genotyping of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Alanine; Arginine; Aspartic Acid; Codon; Cysteine; DNA, Neoplasm; Exons; Forecasting; Genes, ras; Genotype; Glycine; Humans; Leucine; Mutation; Pancreas; Pancreatic Neoplasms; Serine; Survival Rate; Valine | 1994 |
Interleukin-10 stimulates rat pancreatic islets in vitro, but fails to protect against interleukin-1.
Topics: Animals; Cells, Cultured; DNA; Drug Interactions; Glucose; Humans; Insulin; Insulin Secretion; Insulinoma; Interleukin-1; Interleukin-10; Islets of Langerhans; Kinetics; Leucine; Male; Pancreatic Neoplasms; Proinsulin; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tritium; Tumor Cells, Cultured | 1993 |
Protein metabolism in glucagonoma.
Topics: Adult; Amino Acids; Blood Glucose; C-Peptide; Deuterium; Female; Glucagon; Glucagonoma; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Reference Values; Tyrosine | 1999 |
Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion.
Topics: Animals; Arginine; Butyrates; Calcium; Calcium Channel Blockers; Calcium Channels; Coumaric Acids; Diazoxide; Glucose; Insulin; Insulin Secretion; Insulinoma; Ion Channel Gating; Ion Transport; Islets of Langerhans; Isoleucine; Keto Acids; Leucine; Membrane Potentials; Membrane Proteins; Mitochondria; Pancreatic Neoplasms; Phenylpyruvic Acids; Potassium Channels; Secretory Rate; Sodium Azide; Sodium Cyanide; Tumor Cells, Cultured; Valine; Verapamil | 2000 |
Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration.
Topics: alpha-Amylases; Amino Acid Sequence; Animals; Cell Movement; Cell Size; Extracellular Matrix; Genes, Dominant; Humans; Hyaluronan Receptors; Leucine; Ligands; Matrix Metalloproteinase 14; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mice; Molecular Sequence Data; Neoplasm Invasiveness; Pancreatic Neoplasms; Phenylalanine; Plant Proteins; Protein Processing, Post-Translational; Sequence Deletion; Solubility; Sulfones; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Trypsin Inhibitors; Tumor Cells, Cultured | 2001 |
Hypoglycemia: a perspective.
Topics: Adenoma, Islet Cell; Citric Acid Cycle; Diabetes Complications; Diazoxide; Female; Glucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Liver; Liver Diseases; Middle Aged; Muscles; Pancreatic Neoplasms; Streptozocin; Tolbutamide | 1975 |
Qualitative abnormality of insulin secretion in a case with insulinoma.
Topics: Adenoma; Adenoma, Islet Cell; Blood Glucose; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Microscopy, Electron; Middle Aged; Pancreatic Neoplasms | 1975 |
Some observations on blood amino acid concentrations during L-leucine loading tests on a patient with an insulin producing tumor.
Topics: Adenoma, Islet Cell; Adult; Aged; Amino Acids; Female; Humans; Leucine; Male; Middle Aged; Pancreatic Neoplasms | 1975 |
The clinical diagnosis of insulinoma.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Glucagon; Humans; Insulin; Insulin Secretion; Leucine; Pancreatic Neoplasms | 1979 |
The diagnosis of insulinoma in a child in the absence of fasting hyperinsulinemia.
Topics: Adenoma, Islet Cell; Blood Glucose; Child; Fasting; Female; Glucose; Glycogen; Humans; Hypoglycemia; Insulin; Insulin Secretion; Ketone Bodies; Leucine; Pancreatic Neoplasms | 1979 |
Pharmacokinetic and imaging studies of the hepatobiliary agent 99mTc-pyridoxal leucine.
Topics: Animals; Carcinoma; Cholelithiasis; Dogs; Humans; Leucine; Liver Diseases; Mice; Pancreatic Neoplasms; Pyridoxal; Rabbits; Radionuclide Imaging; Technetium | 1978 |
Carboxypeptidase H processing and secretion in rat clonal beta-cell lines.
Topics: Animals; Carboxypeptidase H; Carboxypeptidases; Cell Membrane; Clone Cells; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Insulin; Insulin Secretion; Insulinoma; Kinetics; Leucine; Pancreatic Neoplasms; Protein Processing, Post-Translational; Rats | 1992 |
Mechanisms of vasoactive intestinal peptide release in short-term culture of vasoactive intestinal peptide-producing tumor.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Egtazic Acid; Female; Humans; Immunohistochemistry; Leucine; Middle Aged; Pancreatic Neoplasms; Radioimmunoassay; Vasoactive Intestinal Peptide; Verapamil; Vipoma | 1988 |
Inhibition by a nonmetabolized analogue of L-leucine of protein biosynthesis in tumoral pancreatic islet cells.
Topics: Adenoma, Islet Cell; Amino Acids; Amino Acids, Cyclic; Keto Acids; Leucine; Neoplasm Proteins; Pancreatic Neoplasms; Phenylalanine; Serine; Tumor Cells, Cultured | 1989 |
Characterization of somatostatin receptors which mediate inhibition of insulin secretion in RINm5F insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Binding, Competitive; Cell Line; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Kinetics; Leucine; Pancreatic Neoplasms; Rats; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin | 1987 |
Distribution of somatostatin receptors in RINm5F insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Cell Fractionation; Cell Membrane; Colforsin; Cytoplasmic Granules; Cytosol; Glucagon; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Iodine Radioisotopes; Kinetics; Leucine; Microsomes; Pancreatic Neoplasms; Rats; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin; Tumor Cells, Cultured | 1988 |
Cellular toxicity of pancreatic carcinogens.
Topics: Animals; Azaserine; Carcinogens; Cricetinae; Glutamine; Leucine; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Protein Biosynthesis; Rats; Rats, Inbred Strains; Streptozocin; Tritium | 1986 |
Acromegaly due to secretion of growth hormone by an ectopic pancreatic islet-cell tumor.
Topics: Acromegaly; Adenoma, Islet Cell; DNA, Circular; Growth Hormone; Hormones, Ectopic; Humans; In Vitro Techniques; Leucine; Male; Mesentery; Middle Aged; Nucleic Acid Hybridization; Pancreatic Neoplasms; Paraneoplastic Endocrine Syndromes; Peritoneal Neoplasms; RNA, Messenger; Tritium | 1985 |
Five new insulin-producing cell lines with differing secretory properties.
Topics: Adenoma, Islet Cell; Animals; Calcium; Cell Line; Glucagon; Glucose; Insulin; Insulin Secretion; Leucine; Microscopy, Electron; Microscopy, Phase-Contrast; Pancreatic Neoplasms; Potassium; Rats; Theophylline | 1986 |
In vitro studies of the rate of proinsulin and insulin turnover in seven human insulinomas.
Topics: Adenoma, Islet Cell; Animals; Cattle; Centrifugation, Density Gradient; Chromatography, Gel; Cytoplasmic Granules; Humans; In Vitro Techniques; Insulin; Iodine Radioisotopes; Leucine; Microscopy, Electron; Mitochondria; Pancreatic Neoplasms; Proinsulin; Rats; Staining and Labeling; Subcellular Fractions; Tritium | 1973 |
Biochemical studies in a patient with hyperinsulinism.
Topics: Adenoma, Islet Cell; Adult; Female; Glucagon; Glucose Tolerance Test; Humans; Hydrocortisone; Hyperinsulinism; Hypoglycemia; Leucine; Pancreatic Neoplasms; Tolbutamide | 1966 |
Insulin-secreting islet-cell tumours of the pancreas.
Topics: Adenoma, Islet Cell; Adult; Duodenum; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Pancreatectomy; Pancreatic Neoplasms; Tolbutamide | 1967 |
Insulin secretion by insuloma and normal pancreas slices. Studies in a patient with multiple endocrine adenomata.
Topics: Adenoma; Adenoma, Islet Cell; Adult; Female; Glucose; Glucose Tolerance Test; Humans; In Vitro Techniques; Insulin; Leucine; Mannose; Pancreas; Pancreatectomy; Pancreatic Neoplasms; Parathyroid Neoplasms; Polycystic Kidney Diseases; Tolbutamide | 1968 |
[Current methods of study and morphologic findings in B-cell adenoma of the pancreas].
Topics: Adenoma, Islet Cell; Adolescent; Blood Glucose; Diagnosis, Differential; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Leucine; Microscopy, Electron; Pancreas; Pancreatic Neoplasms; Tolbutamide | 1967 |
Islet cell tumors of the pancreas.
Topics: Adenoma, Islet Cell; Aged; Fasting; Female; Humans; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Tolbutamide | 1969 |
Plasma insulin studies in the diagnosis of insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Tolbutamide | 1969 |
Planning the appropriate operations for islet cell tumors of the pancreas.
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Glucose Tolerance Test; Humans; Leucine; Neoplasm Metastasis; Pancreatic Neoplasms; Radionuclide Imaging; Tolbutamide | 1970 |
Medical grand rounds at Yale-New Haven Hospital. Diagnosis and management of hypoglycemia.
Topics: Adenoma, Islet Cell; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Tolbutamide | 1970 |
[Apropos of 2 cases of insulinoma. Note on the effect of hypoglycemic effect of leucine].
Topics: Adenoma, Islet Cell; Aortography; Female; Humans; Hyperglycemia; Hypoglycemia; Leucine; Middle Aged; Pancreas; Pancreatic Neoplasms | 1969 |
Islet cell tumor with hypoglycemia.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Radioimmunoassay; Tolbutamide | 1971 |
[2 cases of Langerhans adenoma].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Islet Cell; Adult; Aged; Angiography; Celiac Artery; Female; Gastrointestinal Hemorrhage; Glucagon; Humans; Hypoglycemia; Insulin; Intracranial Arteriosclerosis; Leucine; Mesenteric Arteries; Obesity; Pancreatectomy; Pancreatic Neoplasms; Pregnancy; Pregnancy Complications; Prognosis; Tolbutamide | 1969 |
Islet cell adenomatosis and adenoma in an infant.
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Diazoxide; Glucose; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Leucine; Male; Pancreatectomy; Pancreatic Neoplasms; Prednisone; Tolbutamide | 1971 |
Insulin and glucose patterns in control subjects and in proved insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Child; False Negative Reactions; Fasting; Female; Glucagon; Humans; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Time Factors; Tolbutamide | 1971 |
Proinsulin and insulin content of subcellular fractions from an islet adenoma.
Topics: Adenoma, Islet Cell; Animals; Antigens; Cell Nucleus; Centrifugation; Chromatography, Gel; Electrophoresis, Disc; Guinea Pigs; Humans; Insulin; Iodine Isotopes; Islets of Langerhans; Leucine; Male; Microsomes; Middle Aged; Mitochondria; Pancreatic Neoplasms; Proinsulin; Subcellular Fractions; Swine; Tritium | 1972 |
Beta cell adenoma in a child with hypoglycemia controlled with diazoxide.
Topics: Adenoma, Islet Cell; Blood Glucose; Child, Preschool; Diazoxide; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Microscopy, Electron; Pancreatectomy; Pancreatic Neoplasms; Splenectomy; Tolbutamide | 1972 |
Insulinoma diagnosed by insulin immunoassay and angiography.
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Child; Humans; Hypoglycemia; Immunoassay; Insulin; Leucine; Male; Pancreatic Neoplasms; Proinsulin; Tolbutamide | 1972 |
Various tests in the evaluation of islet cell adenomas.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Glucagon; Humans; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Proinsulin; Tolbutamide | 1973 |
Proinsulin and insulin release with a human insulinoma and adjacent nonadenomatous pancreas.
Topics: Adenoma, Islet Cell; Chromatography, Gel; Diazoxide; Epinephrine; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Iodine Isotopes; Leucine; Pancreas; Pancreatic Neoplasms; Proinsulin; Tritium | 1973 |
[Functioning beta-insular tumors of the pancreas. Principal diagnostic tests].
Topics: Adenoma, Islet Cell; Aortography; Blood Glucose; Fasting; Glucose Tolerance Test; Humans; Leucine; Methods; Pancreatic Neoplasms; Radionuclide Imaging; Tolbutamide | 1973 |
[Exploration of hypoglycemia].
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Diazoxide; Diet; Fasting; Glucagon; Hormones, Ectopic; Humans; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Medical History Taking; Pancreatic Neoplasms; Physical Examination; Time Factors; Tolbutamide | 1974 |
[Atypical case of insulinoma (author's transl)].
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Fasting; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Middle Aged; Pancreatic Neoplasms; Tolbutamide; Ultrasonography | 1974 |
[Hypoglycemia].
Topics: Child; Dietary Carbohydrates; Epinephrine; Gastrointestinal Hormones; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Intestinal Absorption; Leucine; Liver Glycogen; Pancreatic Neoplasms; Thyroid Hormones; Tolbutamide | 1973 |
[Functional exploration of insulin secretion in sponteaneous hypoglycemia].
Topics: Adenoma; Arginine; Glucagon; Glucose; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Pancreas; Pancreatic Neoplasms; Tolbutamide | 1967 |
[On the behavior of the so-called leucine aminopeptidase (LAP) in the serum during the application of various substrates].
Topics: Adolescent; Adult; Aged; Animals; Aspartate Aminotransferases; Biliary Tract Diseases; Cholestasis; Female; Glycine; Humans; Leucine; Leucyl Aminopeptidase; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Myocardial Infarction; Neoplasm Metastasis; Pancreatic Neoplasms; Rats | 1968 |