leucine and Non-alcoholic Fatty Liver Disease

leucine has been researched along with Non-alcoholic Fatty Liver Disease in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (35.71)24.3611
2020's9 (64.29)2.80

Authors

AuthorsStudies
Capparelli, R; Cuomo, P; Iannelli, A; Iannelli, D1
Chen, R; Guo, F; Hao, H; Hu, W; Kong, L; Liu, Z; Lu, Y; Wang, X; Wei, P1
Bloks, VW; Bournez, C; de Bruin, A; de Neck, SM; Fuh, MM; Ginsberg, HN; Heeren, J; Huijkman, NCA; Hussain, MM; Kloosterhuis, NJ; Koster, MH; Kuipers, J; Kuivenhoven, JA; Rajan, S; Rimbert, A; Scheja, L; Smit, M; Tharehalli, U; van de Sluis, B; van Westen, GJP; van Zwol, W; Wolters, JC; Zimmerman, P1
Abraham, SJK; Dedeepiya, VD; Ikewaki, N; Iwasaki, M; Levy, GA; Preethy, S; Raghavan, K; Ranganathan, N; Senthilkumar, R; Srinivasan, S; Yamamoto, N1
Hu, Q; Hua, C; Huo, G; Jiang, H; Li, S; Wu, Y; Zhou, F; Zhu, H1
Aebi, A; Annunziato, S; Beckmann, N; Bollepalli, L; Bouwmeester, T; Brousseau, M; Brun, V; Carbone, W; d'Ario, G; Fischer, A; Fischer, B; Genoud, C; Graff Meyer, A; Ksiazek, I; Ley, S; Matadamas-Guzman, ML; Nigsch, F; O'Donnell, P; Obrecht, M; Orsini, V; Osmont, A; Penno, C; Richards, SM; Roma, G; Ruffner, H; Saponara, E; Saravanan, C; Schadt, HS; Tchorz, JS; Terracciano, LM; Tropberger, P; Turner, J; Wang, ZY1
Bi, Y; Chen, Y; Kong, L; Li, M; Lu, J; Ning, G; Wang, T; Wang, W; Wang, Y; Xu, M; Xu, Y; Ye, C; Zhao, Z; Zheng, J1
Hao, H; Hu, W; Li, J; Li, S; Liu, Z; Lu, Y; Qi, X; Wang, X; Wen, S; Yu, W; Zhou, H1
Baum, SJ; Chakravarthy, MV; Chera, H; Gunn, NT; Harrison, SA; Kohli, A; Koziel, MJ; Patil, R; Younes, ZH; Zhao, J1
Alonso, C; Barritt, AS; Chalasani, N; Flores, O; Gil-Redondo, R; Iruarrizaga-Lejarreta, M; Kolterman, O; Middleton, MS; Rinella, M; Siddiqui, MS; Sirlin, CB; Vuppalanchi, R; Zemel, MB1
Afolabi, PR; Almehmadi, AA; Byrne, CD; Calder, PC; Scorletti, E; Smith, DE1
Loomba, R; Noureddin, M1
Chen, X; Dong, B; Geng, L; Li, T; Li, X; Miskowiec, M1
Aranibar, N; Cherrington, NJ; Lake, AD; Lehman-McKeeman, LD; Novak, P; Reily, MD; Robertson, DG; Shipkova, P; Vaillancourt, RR1

Reviews

2 review(s) available for leucine and Non-alcoholic Fatty Liver Disease

ArticleYear
Role of Branched-Chain Amino Acid Metabolism in Type 2 Diabetes, Obesity, Cardiovascular Disease and Non-Alcoholic Fatty Liver Disease.
    International journal of molecular sciences, 2022, Apr-13, Volume: 23, Issue:8

    Topics: Amino Acids, Branched-Chain; Animals; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Metabolic Diseases; Non-alcoholic Fatty Liver Disease; Obesity

2022
Causal effect of lower birthweight on non-alcoholic fatty liver disease and mediating roles of insulin resistance and metabolites.
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:4

    Topics: Adult; Alanine; Birth Weight; Child; Genome-Wide Association Study; Humans; Insulin Resistance; Isoleucine; Leucine; Non-alcoholic Fatty Liver Disease; Pediatric Obesity; Polymorphism, Single Nucleotide; Valine

2023

Trials

2 trial(s) available for leucine and Non-alcoholic Fatty Liver Disease

ArticleYear
Safety, Tolerability, and Biologic Activity of AXA1125 and AXA1957 in Subjects With Nonalcoholic Fatty Liver Disease.
    The American journal of gastroenterology, 2021, 12-01, Volume: 116, Issue:12

    Topics: Acetylcysteine; Administration, Oral; Arginine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Female; Glutamine; Humans; Isoleucine; Leucine; Liver; Magnetic Resonance Imaging; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Single-Blind Method; Treatment Outcome; Valine

2021
Randomised clinical trial: a leucine-metformin-sildenafil combination (NS-0200) vs placebo in patients with non-alcoholic fatty liver disease.
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:12

    Topics: Adult; Alanine Transaminase; Cohort Studies; Double-Blind Method; Drug Combinations; Female; Humans; Leucine; Lipids; Magnetic Resonance Imaging; Male; Metformin; Non-alcoholic Fatty Liver Disease; Sildenafil Citrate

2018

Other Studies

10 other study(ies) available for leucine and Non-alcoholic Fatty Liver Disease

ArticleYear
Effects of serum branched-chain amino acids on nonalcoholic fatty liver disease and subsequent cardiovascular disease.
    Hepatology international, 2022, Volume: 16, Issue:6

    Topics: Amino Acids, Branched-Chain; Cardiovascular Diseases; Cohort Studies; Humans; Isoleucine; Leucine; Non-alcoholic Fatty Liver Disease; Valine

2022
Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.
    Hepatology (Baltimore, Md.), 2023, 11-01, Volume: 78, Issue:5

    Topics: Animals; Apolipoproteins B; Atherosclerosis; Female; Humans; Leucine; Lipoproteins, VLDL; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Small Leucine-Rich Proteoglycans; Triglycerides

2023
Two unique biological response-modifier glucans beneficially regulating gut microbiota and faecal metabolome in a non-alcoholic steatohepatitis animal model, with potential applications in human health and disease.
    BMJ open gastroenterology, 2022, Volume: 9, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Firmicutes; Fructose; Gastrointestinal Microbiome; Glucans; Humans; Isoleucine; Leucine; Metabolome; Mice; Non-alcoholic Fatty Liver Disease; Ornithine; RNA, Ribosomal, 16S; Spermidine; Succinic Acid; Telmisartan; Tryptophan; Water

2022
    Nutrients, 2022, Oct-01, Volume: 14, Issue:19

    Topics: Agaricales; Animals; Antioxidants; Arginine; Biomarkers; Diet, High-Fat; Fucose; Galactose; Glucose; Glycerides; Glycerol; Isoleucine; Leucine; Lipid Metabolism; Lipid Metabolism Disorders; Liver; Mannose; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phospholipids; Polysaccharides; Proline; Spectroscopy, Fourier Transform Infrared; Steroids; Valine; Xylose

2022
Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease.
    The American journal of pathology, 2023, Volume: 193, Issue:2

    Topics: Animals; beta Catenin; Cholesterol; Diet, High-Fat; Leucine; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Receptors, G-Protein-Coupled

2023
Effects of
    Annals of medicine, 2021, Volume: 53, Issue:1

    Topics: Aged; Amino Acids, Branched-Chain; Cardiovascular Diseases; China; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Incidence; Isoleucine; Leucine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Polymorphism, Single Nucleotide; Protein Phosphatase 2C; Valine

2021
The characterisation of hepatic mitochondrial function in patients with non-alcoholic fatty liver disease (NAFLD) using the
    Journal of breath research, 2018, 07-19, Volume: 12, Issue:4

    Topics: Adult; Breath Tests; Carbon Isotopes; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Keto Acids; Leucine; Linear Models; Male; Middle Aged; Mitochondria, Liver; Multivariate Analysis; Non-alcoholic Fatty Liver Disease

2018
Editorial: role of leucine-metformin-sildenafil combination in the treatment of nonalcoholic fatty liver disease (NAFLD).
    Alimentary pharmacology & therapeutics, 2018, Volume: 48, Issue:3

    Topics: Humans; Hypoglycemic Agents; Leucine; Metformin; Non-alcoholic Fatty Liver Disease; Sildenafil Citrate

2018
Branched-chain amino acids alleviate nonalcoholic steatohepatitis in rats.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2013, Volume: 38, Issue:8

    Topics: Amino Acids, Branched-Chain; Animals; Diet, High-Fat; Leucine; Liver; Non-alcoholic Fatty Liver Disease; Rats

2013
Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease.
    Amino acids, 2015, Volume: 47, Issue:3

    Topics: Carnitine; Female; Gene Expression Profiling; Humans; Isoleucine; Leucine; Male; Metabolomics; Non-alcoholic Fatty Liver Disease; Signal Transduction; Valine

2015