leucine and Myelodysplastic Syndromes

leucine has been researched along with Myelodysplastic Syndromes in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (50.00)	18.2507
2000's	1 (10.00)	29.6817
2010's	3 (30.00)	24.3611
2020's	1 (10.00)	2.80

Authors

Authors	Studies
Cermak, J; Dyr, JE; Gasova, Z; Ignjatovic, V; Majek, P; Pecankova, K; Pecherkova, P; Sovova, Z	1
Bello, E; Boultwood, J; Kerry, J; Killick, S; Kušec, R; Pellagatti, A; Raynaud, S; Singh, S; Yip, BH	1
Ebert, BL; Steensma, DP	1
Berliner, N; Ebert, BL; Khanna-Gupta, A; Levine, M; Look, AT; Narla, A; Paw, BH; Payne, EM; Sun, H; Virgilio, M	1
Hishita, T; Kawanishi, S; Miura, Y; Nishihara, T; Tada-Oikawa, S; Tohyama, K; Tohyama, Y; Uchiyama, T; Yoshida, Y	1
Arima, T; Chyuma, Y; Hanada, S; Nishimata, H; Saito, T; Utsunomiya, A	1
Saito, Y; Usuka, Y	1
Im, T; Nakao, H; Oohira, H; Ota, K; Sannomiya, Y; Sasaki, A; Tatsumi, N; Yasui, Y	1
Fukutani, H; Kimura, I; Miura, Y; Mizoguchi, H; Naoe, T; Ohno, R; Ohshima, T; Omine, M; Saito, H; Tomonaga, M	1
Saito, Y; Uzuka, Y	1

Trials

1 trial(s) available for leucine and Myelodysplastic Syndromes

Article	Year
Treatment of myelodysplastic syndromes with orally administered N-(2S, 3R)-3-amino-2-hydroxy-4-phenylbutyryl-L-leucine (ubenimex). Japanese journal of clinical oncology, 1991, Volume: 21, Issue:4 Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aminopeptidases; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Child; Female; Humans; Leucine; Leukemia; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies	1991

Article

Year

Treatment of myelodysplastic syndromes with orally administered N-(2S, 3R)-3-amino-2-hydroxy-4-phenylbutyryl-L-leucine (ubenimex).

Japanese journal of clinical oncology, 1991, Volume: 21, Issue:4

Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aminopeptidases; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Child; Female; Humans; Leucine; Leukemia; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies

1991

Other Studies

9 other study(ies) available for leucine and Myelodysplastic Syndromes

Article	Year
Mass spectrometry, data re-analysis, and homology modelling predict posttranslational modifications of leucine-rich alpha-2-glycoprotein as a marker of myelodysplastic syndrome. Cancer biomarkers : section A of Disease markers, 2022, Volume: 34, Issue:3 Topics: Biomarkers; Glycoproteins; Humans; Leucine; Mass Spectrometry; Myelodysplastic Syndromes; Protein Processing, Post-Translational	2022
L-leucine increases translation of Haematologica, 2018, Volume: 103, Issue:11 Topics: Autoantigens; Cells, Cultured; Chromosome Deletion; Chromosomes, Human, Pair 5; Erythroblasts; Female; Humans; Leucine; Male; Myelodysplastic Syndromes; Protein Biosynthesis; Ribonucleoproteins; Ribosomal Proteins; SS-B Antigen	2018
Initial experience with L-leucine therapy in myelodysplastic syndromes with associated chromosome 5q deletion. Blood, 2013, May-23, Volume: 121, Issue:21 Topics: Aged; Chromosome Deletion; Chromosomes, Human, Pair 5; Female; Humans; Leucine; Male; Middle Aged; Myelodysplastic Syndromes; Treatment Outcome	2013
L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway. Blood, 2012, Sep-13, Volume: 120, Issue:11 Topics: Anemia, Diamond-Blackfan; Anemia, Macrocytic; Animals; Animals, Genetically Modified; Cells, Cultured; Chromosome Deletion; Chromosomes, Human, Pair 5; Disease Models, Animal; Embryo, Nonmammalian; Embryonic Development; Hematinics; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leucine; Myelodysplastic Syndromes; Ribosomal Proteins; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation; Zebrafish; Zebrafish Proteins	2012
Caspase-3 activation by lysosomal enzymes in cytochrome c-independent apoptosis in myelodysplastic syndrome-derived cell line P39. Cancer research, 2001, Apr-01, Volume: 61, Issue:7 Topics: Anti-Bacterial Agents; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cathepsin L; Cathepsins; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Endopeptidases; Enzyme Activation; Enzyme Inhibitors; Etoposide; Humans; Hydrogen-Ion Concentration; Intracellular Membranes; Leucine; Lysosomes; Macrolides; Membrane Potentials; Mitochondria; Myelodysplastic Syndromes; Proton-Translocating ATPases; Vacuolar Proton-Translocating ATPases	2001
[Hemolytic anemia complicated with Behçet's disease and myelodysplastic syndrome]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1992, Volume: 33, Issue:3 Topics: Adult; Anemia, Hemolytic; Behcet Syndrome; Female; Humans; Leucine; Myelodysplastic Syndromes	1992
Bestatin treatment of myelodysplastic syndromes and chronic myelogenous leukemia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1991, Volume: 45, Issue:2-3 Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Busulfan; Drug Therapy, Combination; Female; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Myelodysplastic Syndromes	1991
Effects of ubenimex, a biological response modifier, on myelodysplastic syndrome and chronic leukemia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1991, Volume: 45, Issue:2-3 Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Female; Humans; Immunologic Factors; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Myelodysplastic Syndromes	1991
Bestatin treatment of myelodysplastic syndromes (MDS) and the effects of bestatin on hematopoiesis in MDS. Acta oncologica (Stockholm, Sweden), 1990, Volume: 29, Issue:6 Topics: Aged; Aged, 80 and over; Bone Marrow; Cells, Cultured; Colony-Forming Units Assay; Female; Hematopoiesis; Humans; Leucine; Male; Middle Aged; Myelodysplastic Syndromes; T-Lymphocytes	1990