leucine has been researched along with Multiple Myeloma in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (91.18) | 18.7374 |
| 1990's | 2 (2.94) | 18.2507 |
| 2000's | 2 (2.94) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Kaçmaz, M; Oğuzman, H | 1 |
| Ichijo, T; Joshita, S; Kawakami, F; Kobayashi, H; Nakazawa, H; Sugiura, A; Umemura, T; Wakabayashi, SI; Yamashita, Y; Yamazaki, T | 1 |
| Irvine, AE; Lynas, J; Magill, L; Morris, TC; Walker, B | 1 |
| Abbas, AK; Bach, BA; Greene, MI; Perry, LL | 1 |
| Galfrè, G; Milstein, C | 1 |
| Hossfeld, DK; Linder, KH; Lunscken, C; Schmitt-Gräff, A; Wetter, O | 1 |
| Cohen, AM; Djaldetti, M; Fishman, P; Winder, A | 1 |
| Bast, BJ; De Gast, GC; Post, J; Vooijs, WC | 1 |
| Grujić, M; Renko, M | 1 |
| Bernengo, MG; Boccadoro, M; Conte, P; Marinone, C; Masera, P; Pileri, A | 1 |
| Eagon, PK; Heath, EC | 1 |
| Honjo, T; Kawakami, M; Kondo, T; Ono, M | 1 |
| Cooper, DA; Duckett, M; Hammerton, K; Penny, R | 1 |
| Schechter, I | 3 |
| Kaji, H; Parkhouse, ME | 1 |
| Ackermann, A; Baumal, R; Wilson, B | 1 |
| Cieplinski, W; Hajjar, J; Schwink, A; Tomicic, T | 1 |
| Melchers, F; Sela, M | 1 |
| Melchers, F | 1 |
| Coffino, P; Knowles, B; Nathenson, SG; Scharff, MD | 1 |
| Knopf, PM; Lennox, ES; Parkhouse, RM | 1 |
| Schubert, D | 2 |
| Forbes, IJ; Lawton, JM | 1 |
| Munro, A; Ohno, S; Schubert, D | 1 |
| Cohn, M; Schubert, D | 2 |
| Horibata, K; Schubert, D | 1 |
| Salmon, SE; Smith, BA | 1 |
| Della Corte, E; Parkhouse, RM | 1 |
| Goedde, HW; Hoffbauer, RW; Weile, HG | 1 |
| Hanaoka, M; Namba, Y | 1 |
| Epstein, LB; Salmon, SE | 1 |
| Adams, JM; Cory, S; Schmeckpeper, BJ | 1 |
| Parkhouse, RM | 2 |
| Aviv, H; Leder, P; Swan, D | 1 |
| Faust, C; Mach, B; Vassalli, P | 1 |
| Cioli, D; Lennox, ES | 2 |
| Chatterjee, NK; Chuang, DM; Weissbach, H | 1 |
| Knopf, PM; Lennox, ES; Munro, AJ | 1 |
| Buxbaum, J; Scharff, MD | 1 |
| Destree, A; Hyman, R; Knopf, PM | 1 |
| Forbes, IJ; Lawton, JW | 1 |
| Jamieson, JD; Palade, GE; Uhr, JW; Zagury, D | 1 |
| Cohen, S; Cwynarski, MT | 1 |
| Austin, KE; Fudenberg, HH; Levin, AS; Stites, DP | 1 |
| Bargellesi, A; Periman, P; Scharff, MD | 1 |
| Krueger, RG; Shutt, RH | 1 |
| Kimmel, CB; Wang, CZ | 1 |
| Grant, GF; Horibata, K | 1 |
| Fujioka, S; Gallo, RC | 1 |
| Lanzerotti, R; Laskov, R; Scharff, MD | 1 |
| Baumal, R; Potter, M; Scharff, MD | 1 |
| Askonas, BA; Parkhouse, RM | 1 |
| Bevan, MJ | 1 |
| Mushinski, JF | 1 |
| Sherr, CJ; Uhr, JW | 1 |
| Kern, M; Sutherland, EW; Zimmerman, DH | 1 |
| Schenkein, I; Uhr, JW | 1 |
| Buxbaum, J; Franklin, EC; Scharff, MD; Zolla, S | 1 |
| Kabat, EA; Wu, TT | 1 |
| Askonas, BA; Williamson, AR | 1 |
| Todo, A | 1 |
| Hartman, BK; Pettengill, OS; Sorenson, GD | 1 |
1 review(s) available for leucine and Multiple Myeloma
| Article | Year |
|---|---|
Successful treatment by glecaprevir/pibrentasvir followed by hepatoprotective therapy of acute chronic hepatitis exacerbation caused by daratumumab-based regimen for multiple myeloma: Case report and review of the literature.
Topics: Aged; Aminoisobutyric Acids; Antibodies, Monoclonal; Antiviral Agents; Benzimidazoles; Cyclopropanes; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Leucine; Multiple Myeloma; Proline; Pyrrolidines; Quinoxalines; Sulfonamides | 2021 |
67 other study(ies) available for leucine and Multiple Myeloma
| Article | Year |
|---|---|
The Leucine-Rich α2-Glycoprotein-1 Levels in Patients with Multiple Myeloma.
Topics: Glycoproteins; Humans; Interleukin-6; Interleukin-8; Leucine; Multiple Myeloma; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2023 |
Proteasome proteolytic activity in hematopoietic cells from patients with chronic myeloid leukemia and multiple myeloma.
Topics: Apoptosis; Bone Marrow Cells; Cell Line, Tumor; Edetic Acid; Fusion Proteins, bcr-abl; Hematopoietic Stem Cells; HL-60 Cells; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Multiple Myeloma; Neoplasm Proteins; Pepstatins; Protease Inhibitors; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Sulfones; Transfection | 2004 |
Idiotype-specific T cell immunity. I. Generation of effector and suppressor T lymphocytes reactive with myeloma idiotypic determinants.
Topics: Animals; Antibody Formation; Dinitrobenzenes; Epitopes; Hypersensitivity, Delayed; Immunization; Immunoglobulin A; Immunoglobulin Idiotypes; Leucine; Mice; Mice, Inbred BALB C; Multiple Myeloma; T-Lymphocytes; Trinitrobenzenes | 1980 |
Chemical typing of human kappa light chain subgroups expressed by human hybrid myelomas.
Topics: Animals; Cell Line; Humans; Hybridomas; Immunoglobulin kappa-Chains; Immunoglobulin Light Chains; Leucine; Mice; Multiple Myeloma; Spleen | 1982 |
Plasma cell dyscrasias--a comparative study of cell surface properties in plasma cell leukemia and myeloma.
Topics: Adult; Cells, Cultured; Concanavalin A; Dactinomycin; Humans; Leucine; Leukemia, Plasma Cell; Lymphocyte Activation; Lymphocytes; Male; Multiple Myeloma; Phytohemagglutinins; Plasma Cells; Pokeweed Mitogens; Thymidine | 1980 |
The effect of alpha-interferon on thymidine, uridine, and leucine uptake and ultrastructure of peripheral blood mononuclear cells from multiple myeloma patients.
Topics: Aged; Female; Humans; Interferon alpha-2; Interferon-alpha; Leucine; Leukocytes, Mononuclear; Lymphocytes; Male; Microscopy, Electron, Scanning; Multiple Myeloma; Recombinant Proteins; Thymidine; Uridine | 1993 |
Efficacy of an anti-CD138 immunotoxin and doxorubicin on drug-resistant and drug-sensitive myeloma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Survival; DNA; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Humans; Immunotoxins; Leucine; Membrane Glycoproteins; Multiple Myeloma; Protein Biosynthesis; Proteoglycans; Syndecan-1; Syndecans; Tumor Cells, Cultured; Tumor Stem Cell Assay; Verapamil | 1999 |
Aminopeptidase inhibitors bestatin and actinonin inhibit cell proliferation of myeloma cells predominantly by intracellular interactions.
Topics: Aminopeptidases; Buthionine Sulfoximine; Cell Division; Cell Membrane; Enzyme Inhibitors; Humans; Hydroxamic Acids; K562 Cells; Leucine; Multiple Myeloma; Substrate Specificity; U937 Cells | 2002 |
Early recruitment in the human myeloma cell population after cytostatic treatment.
Topics: Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Dactinomycin; Humans; Leucine; Multiple Myeloma; Thymidine; Uridine; Vincristine | 1976 |
Glycoprotein biosynthesis in myeloma cells. Characterization on nonglycosylated immunoglobulin light chain secreted in presence of 2-deoxy-D-glucose.
Topics: Animals; Cell Line; Deoxy Sugars; Deoxyglucose; Glucosamine; Glycoproteins; Immunoglobulin Light Chains; Kinetics; Leucine; Mice; Multiple Myeloma; Neoplasms, Experimental; Peptide Fragments | 1977 |
Purification of immunoglobulin heavy chain messenger RNA by immunoprecipitation from the mouse myeloma tumor, MOPC-31C.
Topics: Animals; Avian Myeloblastosis Virus; Cells, Cultured; DNA; DNA-Directed DNA Polymerase; Immunoglobulin Heavy Chains; Leucine; Mice; Molecular Weight; Multiple Myeloma; Myeloma Proteins; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Peptide Fragments; Polyribosomes; RNA, Messenger | 1977 |
Biosynthesis of immunoglobulin in human immunoproliferative diseases. I. Kinetics of synthesis and secretion of immunoglobulin and protein by bone marrow cells in myeloma.
Topics: Bence Jones Protein; Bone Marrow; Humans; Immunoglobulin A; Immunoglobulin G; Kinetics; Leucine; Multiple Myeloma; Myeloma Proteins | 1978 |
Partial amino acid sequence of the precursor of immunoglobulin light chain programmed by messenger RNA in vitro.
Topics: Amino Acid Sequence; Animals; Carbon Radioisotopes; Cell-Free System; Immunoglobulin Fragments; Immunoglobulin kappa-Chains; Immunoglobulins; Leucine; Mice; Molecular Weight; Multiple Myeloma; Polyribosomes; Protein Biosynthesis; Protein Precursors; RNA, Messenger | 1975 |
Control of J chain biosynthesis in relation to heavy and light chain synthesis, polymerization and secretion.
Topics: Animals; Antibody Formation; Cell Line; Cells, Cultured; Goats; Immune Sera; Immunoglobulin A; Immunoglobulin Fragments; Immunoglobulin G; Immunoglobulin Heavy Chains; Immunoglobulin J-Chains; Immunoglobulin M; Leucine; Leukemia, Experimental; Mice; Multiple Myeloma; Polymers; Precipitin Tests; Rabbits; Tritium | 1975 |
Immunoglobulin biosynthesis in myeloma-associated and casein- and endotoxin-induced murine amyloidosis.
Topics: Amyloid; Amyloidosis; Animals; Carbon Radioisotopes; Caseins; Endotoxins; Fluorescent Antibody Technique; Immune Sera; Immunoglobulins; Kidney; Leucine; Lipopolysaccharides; Liver; Lung; Lymphocytes; Mice; Mice, Inbred Strains; Multiple Myeloma; Myocardium; Plasma Cells; Salmonella typhi; Spleen; Threonine; Tritium; Valine | 1975 |
Kinetics of amino acid transport by human-mouse myeloma hybrids--difference between human immunoglobulin producers and nonproducers.
Topics: Amino Acids; Animals; Biological Transport; Humans; Hybrid Cells; Immunoglobulins; Leucine; Mice; Multiple Myeloma; Puromycin | 1985 |
Search for antibodies against the carbohydrate portion of two mouse myeloma proteins.
Topics: Animals; Antibodies; Antibody Specificity; Bence Jones Protein; Carbohydrates; Epitopes; Galactose; gamma-Globulins; Leucine; Mannose; Mice; Multiple Myeloma; Rabbits; Radioimmunoassay; Tritium; Trypsin | 1970 |
Biosynthesis of the carbohydrate portion of immunoglobulins. Kinetics of synthesis and secretion of [3H] leucine-, [3H] galactose- and [3H] mannose-labelled myeloma protein by two plasma-cell tumours.
Topics: Animals; Carbon Isotopes; Culture Techniques; Fucose; Galactose; gamma-Globulins; Glucosamine; Immunoglobulins; Kinetics; Leucine; Mannose; Mice; Multiple Myeloma; Tritium | 1970 |
Suppression of immunoglobulin synthesis by cellular hybridization.
Topics: Animals; Carbon Isotopes; Cell Fusion; Cell Line; Cytogenetics; Fibroblasts; gamma-Globulins; Hybridization, Genetic; Immunoglobulins; In Vitro Techniques; Leucine; Mice; Multiple Myeloma; Peptide Biosynthesis; Threonine; Tritium; Valine | 1971 |
Biosynthetic units of an immunoglobulin heavy chain.
Topics: Carbon Isotopes; gamma-Globulins; In Vitro Techniques; Leucine; Multiple Myeloma; Neoplasm Proteins; RNA, Messenger; Tritium | 1967 |
Immunoglobulin assembly in a mouse myeloma.
Topics: Animals; Antigen-Antibody Reactions; Centrifugation, Density Gradient; Chemical Precipitation; Clone Cells; Electrophoresis; gamma-Globulins; In Vitro Techniques; Leucine; Mice; Multiple Myeloma; Rabbits; Ribosomes; Tritium | 1968 |
Autoradiographic analysis of proteins synthesized by human lymphocytes. I. Multiple myeloma and macroglobulinaemia. Evidence relevant to clonal selection theory.
Topics: Antibody Formation; Autoradiography; Carbon Isotopes; gamma-Globulins; Humans; Immunoelectrophoresis; Immunoglobulin G; Immunoglobulin M; Leucine; Lymphocytes; Multiple Myeloma; Waldenstrom Macroglobulinemia | 1969 |
Immunoglobulin biosynthesis. I. A myeloma variant secreting light chain only.
Topics: Animals; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; gamma-Globulins; Immune Sera; Karyotyping; Kinetics; Leucine; Mice; Multiple Myeloma; Neoplasms, Experimental; Peptides; Proteinuria; Time Factors; Tritium; Trypsin | 1968 |
Immunoglobulin biosynthesis. 3. Blocks in defective synthesis.
Topics: Animals; Centrifugation, Density Gradient; Chemical Precipitation; Electrophoresis, Disc; gamma-Globulins; Leucine; Mice; Multiple Myeloma; Mutation; Neoplasms, Experimental; Proteins; Ribonucleases; Ribosomes; Spectrophotometry; Tritium | 1968 |
Immunoglobulin biosynthesis. II. Four independently isolated myeloma variants.
Topics: Animals; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; gamma-Globulins; Immune Sera; Karyotyping; Leucine; Mice; Multiple Myeloma; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Peptides; Proteins; Species Specificity; Transplantation, Homologous; Tritium | 1968 |
Sandwich solid phase radioimmunoassays for the characterization of human immunoglobulins synthesized in vitro.
Topics: Antibody Formation; Antibody-Producing Cells; Antigen-Antibody Reactions; Antigens; Bone Marrow; Bone Marrow Cells; Culture Techniques; Erythrocytes; gamma-Globulins; Humans; Leucine; Leukocyte Count; Methods; Multiple Myeloma; Plasma Cells; Radioimmunoassay; Tritium | 1970 |
Assembly and secretion of immunoglobulin A.
Topics: Animals; Antibody Specificity; Carbohydrate Metabolism; Carbon Radioisotopes; Carrier Proteins; Cattle; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chromatography, Gel; Disulfides; Electrophoresis, Polyacrylamide Gel; Immune Sera; Immunoglobulin A; Immunoglobulin J-Chains; Isomerases; Leucine; Liver; Mice; Multiple Myeloma; Myeloma Proteins; Oxidation-Reduction; Plasmacytoma; Polymers; Tritium | 1974 |
Incorporation of 14C- and 3H-L-leucine into immunoglobulins of different class specifity (radial-diffusion method).
Topics: Autoradiography; Carbon Radioisotopes; Cells, Cultured; Humans; Immune Sera; Immunodiffusion; Immunoglobulins; Isotope Labeling; Leucine; Multiple Myeloma; Myeloma Proteins; Tritium | 1974 |
Immunocytology of cultured IgM-forming cells of mouse. I. Requirement of phagocytic cell factor for the growth of IgM-forming tumor cells in tissue culture.
Topics: Acid Phosphatase; Animals; Antibody Specificity; Antibody-Producing Cells; Cattle; Cell Line; Cyclic AMP; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin Fragments; Immunoglobulin M; Leucine; Mice; Microscopy, Phase-Contrast; Mitosis; Multiple Myeloma; Phagocytosis; Rabbits; Thymidine; Tritium; Trypsin; Trypsin Inhibitors | 1972 |
The production of interferon by malignant plasma cells from patients with multiple myeloma.
Topics: Bone Marrow Cells; Cells, Cultured; Culture Techniques; Fibroblasts; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulins; Interferons; Lectins; Leucine; Macroglobulins; Multiple Myeloma; Myeloma Proteins; Plasma Cells; Radioimmunoassay; Tritium; Vesicular stomatitis Indiana virus; Viral Plaque Assay; Waldenstrom Macroglobulinemia | 1974 |
Translation of immunoglobulin mRNAs in a wheat germ cell-free system.
Topics: Aminoacylation; Animals; Carbon Radioisotopes; Cell Line; Cell-Free System; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; Germ-Free Life; Immunoglobulin G; Immunoglobulins; Leucine; Methionine; Mice; Mice, Inbred BALB C; Molecular Weight; Multiple Myeloma; Peptide Chain Termination, Translational; Plants; Plasmacytoma; Protein Biosynthesis; RNA, Messenger; RNA, Neoplasm; Sulfur Radioisotopes; Time Factors; Triticum | 1974 |
Biosynthesis of J-chain in mouse IgA and IgM.
Topics: Animals; Electrophoresis, Starch Gel; Immunoglobulin A; Immunoglobulins; Leucine; Mice; Molecular Weight; Multiple Myeloma; Neoplasms, Experimental; Peptide Biosynthesis; Peptides; Tritium | 1972 |
Purification and properties of biologically active messenger RNA for a myeloma light chain.
Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Krebs 2; Centrifugation, Density Gradient; Chromatography, Affinity; Chromatography, Ion Exchange; Goats; Leucine; Multiple Myeloma; Myeloma Proteins; Peptides; Precipitin Tests; Ribosomes; RNA, Messenger; RNA, Neoplasm; Sodium Dodecyl Sulfate; Thymine Nucleotides; Tritium; Trypsin | 1972 |
Purification of 14S messenger RNA of immunoglobulin light chain that codes for a possible light-chain precursor.
Topics: Animals; Carbon Isotopes; Cell Fractionation; Cell-Free System; Centrifugation, Density Gradient; Culture Techniques; Electrophoresis, Polyacrylamide Gel; Genetic Code; Immunoglobulins; Leucine; Mice; Molecular Weight; Multiple Myeloma; Myeloma Proteins; Neoplasms, Experimental; Polyribosomes; Protein Precursors; Rabbits; Reticulocytes; RNA, Messenger; Sulfur Isotopes; Tritium | 1973 |
Biologically and chemically pure mRNA coding for a mouse immunoglobulin L-chain prepared with the aid of antibodies and immobilized oligothymidine.
Topics: Animals; Carbon Isotopes; Carcinoma, Krebs 2; Cell Line; Cell-Free System; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; Female; Goats; Immunoassay; Immunoglobulin Fragments; Immunoglobulins; Leucine; Mice; Mice, Inbred BALB C; Multiple Myeloma; Peptides; Polyribosomes; Precipitin Tests; Protein Biosynthesis; RNA, Messenger | 1973 |
Immunoglobulin nascent chains on membrane-bound ribosomes of myeloma cells.
Topics: Animals; Antibody Formation; Carbon Isotopes; Choline; Chromatography, Ion Exchange; Clone Cells; Cytological Techniques; Female; Immunoglobulin Fragments; Leucine; Membranes; Mice; Mice, Inbred BALB C; Multiple Myeloma; Neoplasm Transplantation; Peptides; Precipitin Tests; Rabbits; Ribosomes; RNA, Neoplasm; RNA, Transfer; Tritium | 1973 |
Further studies on eukaryote DNA stimulation of amino acid incorporation in E. coli extracts.
Topics: Adenoviridae; Amino Acids; Aminoacylation; Animals; Bacterial Proteins; Carbon Radioisotopes; Cell-Free System; DNA, Neoplasm; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Escherichia coli; HeLa Cells; Leucine; Mice; Multiple Myeloma; Nucleic Acid Hybridization; Peptide Chain Initiation, Translational; Polyribosomes; Precipitin Tests; Protein Biosynthesis; Rabbits; RNA, Bacterial; Sheep; Transcription, Genetic; Tritium; Uracil Nucleotides | 1974 |
Synthesis of an immunoglobulin light chain: pulse-labeling studies.
Topics: Amino Acid Sequence; Amino Acids; Animals; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Chromatography, Paper; Cyanogen Bromide; Electrophoresis, Paper; Immunoglobulin Fragments; Isotope Labeling; Leucine; Mice; Models, Biological; Multiple Myeloma; Neoplasm Transplantation; Oxidation-Reduction; Peptide Chain Elongation, Translational; Peptides; Templates, Genetic; Time Factors; Tritium; Trypsin; Ultrafiltration | 1973 |
The synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells. VI. Assembly of IgM proteins.
Topics: Animals; Carbon Isotopes; Culture Media; Electrophoresis, Polyacrylamide Gel; Immune Sera; Immunoglobulin Fragments; Immunoglobulin M; Leucine; Methods; Mice; Mice, Inbred BALB C; Molecular Weight; Multiple Myeloma; Neoplasm Transplantation; Threonine; Transplantation, Homologous; Valine | 1973 |
Purification and characterization of nascent chains from immunoglobulin producing cells.
Topics: Animals; Antibody Formation; Cell Fractionation; Chromatography, Ion Exchange; Cycloheximide; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Evaluation Studies as Topic; Female; Hydrogen-Ion Concentration; Immunoglobulin Fragments; Kinetics; Leucine; Mice; Mice, Inbred BALB C; Multiple Myeloma; Peptides; Puromycin; Ribonucleases; Ribosomes; RNA, Neoplasm; RNA, Transfer; Tritium | 1973 |
Antibody-induced changes in expression of an immunoglobulin surface antigen.
Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Antigen-Antibody Reactions; Antigens, Neoplasm; Cell Line; Cytotoxicity Tests, Immunologic; Immune Sera; Immunoglobulin Fab Fragments; Immunoglobulins; Iodine Radioisotopes; Leucine; Lymphoma; Mice; Monoiodotyrosine; Multiple Myeloma; Myeloma Proteins; Papain; Precipitin Tests; Pronase; Rabbits; Sheep; Temperature; Tritium | 1973 |
Use of antibodies for the isolation of biologically pure messenger ribonucleic acid from fully functional eukaryotic cells.
Topics: Amino Acids; Animals; Antibodies; Antigens; Autoradiography; Carbon Radioisotopes; Carcinoma, Krebs 2; Cell Fractionation; Cell-Free System; Female; Genetic Code; Goats; Immunoglobulin Fragments; Leucine; Mice; Multiple Myeloma; Myeloma Proteins; Polyribosomes; Precipitin Tests; RNA, Messenger; RNA, Ribosomal; Sheep; Tritium | 1974 |
Measurements of protein synthesis by lymphocytes in vitro in diseases of the lymphoid tissues.
Topics: Blood Proteins; Carbon Isotopes; Culture Techniques; Humans; Infectious Mononucleosis; Lectins; Leucine; Leukemia, Lymphoid; Leukocyte Count; Lymphocytes; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Plasma; Waldenstrom Macroglobulinemia | 1968 |
[Histoautoradiography study of immunoglobulin biosynthesis of mouse myeloma plasmacytes].
Topics: Animals; Autoradiography; Galactose; Glucosamine; Histocytochemistry; Immunoglobulin G; In Vitro Techniques; Leucine; Mice; Microscopy, Electron; Multiple Myeloma; Plasma Cells; Tritium | 1969 |
Polyclonal immunoglobulin deficiency in myelomatosis and macroglobulinaemia.
Topics: Adult; Agammaglobulinemia; Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Humans; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Isoelectric Focusing; Leucine; Lymph Nodes; Multiple Myeloma; Rabbits; Tritium; Waldenstrom Macroglobulinemia | 1971 |
Immunobiology of human lymphoid cell lines. I. Immunoglobulin biosynthesis in cultures from Hypogammaglobulinemias and paraproteinemias.
Topics: Agammaglobulinemia; Carbon Isotopes; Cell Line; Cells, Cultured; Culture Techniques; Fluorescent Antibody Technique; Humans; Immunoelectrophoresis; Immunoglobulins; Lectins; Leucine; Lymphocytes; Multiple Myeloma; Waldenstrom Macroglobulinemia | 1971 |
Synthesis, assembly, and secretion of globulin by mouse myeloma cells. IV. Assembly of IgA.
Topics: Animals; Carbon Isotopes; Cell Line; Immunoglobulin A; Immunoglobulins; Leucine; Mice; Multiple Myeloma; Myeloma Proteins; Neoplasms, Experimental; Rabbits; Sheep; Threonine; Valine | 1972 |
The effect of actinomycin D and 5-azacytidine on macromolecular synthesis in murine myeloma tumor cells.
Topics: Animals; Cell Line; Cell-Free System; Cytidine; Dactinomycin; Electrophoresis, Disc; Genetic Code; Half-Life; Immunogenetics; Immunoglobulin G; Leucine; Mice; Multiple Myeloma; Myeloma Proteins; Phenylalanine; Rabbits; RNA, Messenger; Tritium; Uridine; Valine | 1972 |
Cytoplasmic RNA in immunologlobulin-secreting myeloma tumor cells. I. Identification and characteristics of a class of heterogeneous RNA.
Topics: Animals; Carbon Isotopes; Cell Fractionation; Cell Line; Cytoplasm; Dactinomycin; Electrophoresis; Ethidium; Immunoelectrophoresis; Immunoglobulins; Kinetics; Leucine; Mice; Molecular Weight; Multiple Myeloma; Neoplasm Proteins; Phosphates; Phosphorus Isotopes; Rabbits; RNA, Messenger; RNA, Neoplasm; Tritium; Uridine | 1972 |
A variant mouse myeloma secreting excess heavy chain.
Topics: Acrylamides; Agar; Animals; Bence Jones Protein; Carbon Isotopes; Chromatography, Gel; Clone Cells; Dinitrophenols; Electrophoresis; Glucosamine; Immunoglobulin A; Immunoglobulins; In Vitro Techniques; Leucine; Mice; Multiple Myeloma; Peptides; Rabbits; Ribosomes; Tritium | 1972 |
Aminoacyl transfer RNA profiles in human myeloma cells.
Topics: Acyltransferases; Aspartic Acid; Carbon Isotopes; Cell Line; Chromatography; Culture Techniques; Humans; Leucine; Lymphocytes; Multiple Myeloma; RNA, Transfer; Serine; Tritium; Tyrosine | 1971 |
Synthesis, assembly and secretion of gamma globulin by mouse myeloma cells. II. Assembly of IgG2b immunoglobulin by MPC 11 tumor and culture cells.
Topics: Animals; Carbon Isotopes; Chromatography, DEAE-Cellulose; Culture Techniques; Cycloheximide; Cytoplasm; Electrophoresis; Immunoglobulin G; Immunoglobulins; Leucine; Mice; Molecular Weight; Multiple Myeloma; Neoplasms, Experimental; Threonine; Valine | 1971 |
Synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells. 3. Assembly of the three subclasses of IgG.
Topics: Animals; Antibody Formation; Carbon Isotopes; Cell Line; Immunoglobulin G; Immunoglobulins; Kinetics; Leucine; Lymph Nodes; Mice; Multiple Myeloma; Peptides; Ribosomes; Threonine; Valine | 1971 |
Assembly of immunoglobulin M. Blocked thiol groups of intracellular 7S subunits.
Topics: Alkylating Agents; Animals; Centrifugation, Density Gradient; Chromatography, Gel; Cysteine; Disulfides; Dithiothreitol; Electrophoresis, Disc; Immunoglobulin G; Immunoglobulins; In Vitro Techniques; Iodoacetates; Leucine; Mice; Multiple Myeloma; Neoplasms, Experimental; Oxidation-Reduction; Polymers; Tritium | 1971 |
Immunoglobulin M biosynthesis. Production of intermediates and excess of light-chain in mouse myeloma MOPC 104E.
Topics: Animals; Centrifugation, Density Gradient; Clone Cells; Disulfides; Electrophoresis, Disc; Immunoglobulin G; Immunoglobulins; In Vitro Techniques; Leucine; Mice; Models, Biological; Multiple Myeloma; Neoplasms, Experimental; Sucrose; Tritium | 1971 |
Interchain disulfide bond formation studied in two mouse myelomas which secrete immunoglobulin A.
Topics: Animals; Electrophoresis, Disc; Goats; Immunochemistry; Immunoglobulin A; Immunoglobulin G; Immunoglobulins; Leucine; Mice; Mice, Inbred Strains; Multiple Myeloma; Myeloma Proteins; Plasma Cells; Plasmacytoma; Polymers; Rabbits; Tritium; Valine | 1971 |
Stability of chromatographic patterns of aminoacyl transfer ribonucleic acid from individual mouse plasmacytomas and variability among different immunoglobulin A producing plasmacytomas and normal organs.
Topics: Amino Acyl-tRNA Synthetases; Animals; Carbon Isotopes; Chromatography; Drug Stability; Immunoglobulin A; Kidney; Leucine; Liver; Male; Mice; Mice, Inbred Strains; Multiple Myeloma; Plasmacytoma; RNA, Transfer; Serine; Spleen; Testis; Time Factors; Tritium; Tyrosine | 1971 |
Immunoglobulin synthesis and secretion. 3. Incorporation of glucosamine into immunoglobulin on polyribosomes.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Glucosamine; Immunoglobulin G; Leucine; Mice; Multiple Myeloma; Neoplasms, Experimental; Protein Binding; Ribosomes; Tritium | 1969 |
Synthesis and secretion of gamma-globulin by lymph node cells, VIII. Order of synthesis of the interchain disulfide linkages of immunoglobulins.
Topics: Animals; Carbon Isotopes; Electrophoresis, Disc; Immunoglobulin G; Immunoglobulins; In Vitro Techniques; Leucine; Lymph Nodes; Mice; Molecular Weight; Multiple Myeloma; Neoplasm Proteins; Peptide Biosynthesis; Rabbits; Sulfides; Surface-Active Agents; Tritium | 1970 |
Immunoglobulin synthesis and secretion, IV. Sites of incorporation of sugars as determined by subcellular fractionation.
Topics: Animals; Carbon Isotopes; Cell Line; Chromatography, Ion Exchange; Chromatography, Thin Layer; Endoplasmic Reticulum; Galactose; Glucosamine; Immunoglobulin G; Immunoglobulins; In Vitro Techniques; Leucine; Mice; Microsomes; Multiple Myeloma; Neoplasm Proteins; Tritium; Valine | 1970 |
Synthesis and assembly of immunoglobulins by malignant human plasmacytes. I. Myelomas producing gamma-chains and light chains.
Topics: Bence Jones Protein; Bone Marrow Examination; Carbon Isotopes; Chromatography, Gel; Culture Techniques; Cytoplasm; Electrophoresis; Glutamates; Humans; Immunoelectrophoresis; Immunoglobulin G; Immunoglobulins; Leucine; Leukemia, Plasma Cell; Multiple Myeloma; Neoplasm Proteins; Plasma Cells; Threonine; Tritium; Ultracentrifugation; Valine | 1970 |
An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity.
Topics: Alanine; Amino Acid Sequence; Analysis of Variance; Animals; Antibodies; Antibody Specificity; Bence Jones Protein; Binding Sites; Genes; Glycine; Histidine; Humans; Immunoglobulin G; Immunoglobulin M; Leucine; Lysine; Mice; Models, Chemical; Multiple Myeloma; Rabbits; Species Specificity; Valine | 1970 |
Immunoglobulin biosynthesis. IV. Carbohydrate attachment to immunoglobulin subunits.
Topics: Animals; Blood Protein Electrophoresis; Carbon Isotopes; Cell Line; Chromatography, Gel; Electrophoresis, Disc; Glucosamine; Glucose; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Leucine; Mice; Molecular Weight; Multiple Myeloma; Neoplasms, Experimental; Protein Binding; Rabbits; Tritium | 1970 |
Immunoglobulin biosynthesis. V. Light chain assembly.
Topics: Animals; Carbon Isotopes; Cell Line; Culture Techniques; Cycloheximide; Electrophoresis, Disc; Gels; Immune Sera; Immunoglobulin G; Immunoglobulins; Kinetics; Leucine; Mice; Molecular Weight; Multiple Myeloma; Rabbits; Ribosomes; Tritium | 1970 |
Interchain disulphide-bond formation in the assembly of immunoglobulin G. Heavy-chain dimer as an intermediate.
Topics: Animals; Ascites; Autoradiography; Carbon Isotopes; Chromatography, Ion Exchange; Electrophoresis; Immunoglobulin G; Leucine; Mice; Multiple Myeloma; Neoplasms, Experimental; Plasma Cells; Proteins; Sulfides; Tritium; Valine | 1968 |
Proliferation and differentiation of hematopoietic cells in hematologic disorders. II. In vitro radioautographic study of leukemic cells.
Topics: Adult; Aged; Culture Techniques; Female; Hematopoiesis; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Thymidine; Tritium; Uridine | 1968 |
Chloramphenicol: effects on mouse myeloma cells in tissue culture.
Topics: Animals; Carbon Isotopes; Cell Division; Chloramphenicol; Culture Techniques; Kinetics; Leucine; Mice; Multiple Myeloma; Neoplasm Proteins | 1969 |