leucine has been researched along with Metastase in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (51.61) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 2 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, G; Fang, C; Guo, L; Guo, S; Song, W; Wang, S; Wang, X; Wei, L; Yang, H; Zhang, H; Zhang, L; Zhao, X; Zhao, Y | 1 |
| Brunetto, SQ; Busanello, ENB; Castelucci, BG; Consonni, SR; de Oliveira, AG; Gomes-Marcondes, MCC; Lima, TI; Machado, G; Marques, AC; Ramos, CD; Silveira, LR; Tobar, N; Vercesi, AE; Viana, LR | 1 |
| Picklo, MJ; Rust, BM; Yan, L | 1 |
| Creighton, CJ; Fradette, JJ; Gibbons, DL; Gibson, LA; Grzeskowiak, CL; Kundu, ST; Rodriguez, LB; Scott, KL | 1 |
| Hou, J; Huang, Y; Jia, Y; Jiang, Y; Li, X; Wang, X; Xu, W; Zhang, J; Zhang, Y; Zou, M | 1 |
| Chen, WY; Hankinson, SE; Holmes, MD; Tamimi, RM; Wang, J | 1 |
| Edgington, T; Huang, H; Janda, K; Liu, C; Sun, C | 1 |
| EVERSOLE, JW; MOSELEY, T | 1 |
| ANAGNOSTOU, E; HADZIYANNIS, S; KAKARI, S; MERICAS, G | 1 |
| SCHOLTZ, DA | 1 |
| FIELD, JB | 1 |
| Bajaj, SP; Cascio, D; Chand, HS; Kisiel, W; Schmidt, AE | 1 |
| Glinskii, OV; Glinsky, GV; Glinsky, VV; Huxley, VH; Pienta, KJ; Raz, A | 1 |
| Hirano, K; Iguchi, K; Nakano, T; Usui, S | 1 |
| Degani, H; Eshhar, Z; Kalchenko, V; Makovitzki, A; Papo, N; Seger, D; Shai, Y | 1 |
| Nishimura, K; Nishino, Y; Noda, Y; Otsu, H; Sakiyama, H | 1 |
| Habu, H; Hoshi, K; Ishii, T; Sunagawa, M; Takeshita, K | 1 |
| Cheater, AJ; Davison, MD; Myers, KA; Rahi-Saund, V; Stern, PL; Young, JA | 1 |
| Glinsky, GV; Glinsky, VV; Kiriakova, G; Metcalf, JB; Mossine, VV; Price, JE | 1 |
| Bellingard-Dubouchaud, V; Bogyo, M; Greenbaum, D; Toba, S; Verhelst, S | 1 |
| Authier, F; Bergeron, JJ; Brodt, P; Chevet, E; Di Guglielmo, GM; Navab, R | 1 |
| Dorner, JL; Hoffmann, WE | 1 |
| Abe, F; Black, PL; Schneider, M; Talmadge, JE | 1 |
| Lenz, BF; Long, C; Pennington, R; Phillips, H; Schneider, M; Talmadge, JE; Tribble, H | 1 |
| Ahsan, A; Bain, DL; Ostrowski, LE; Pagast, P; Patel, A; Schultz, RM; Suthar, BP; Wong, C | 1 |
| DePeyster, FA | 1 |
| Fishman, WH | 1 |
| Hjern, B; Ljunggren, JG; Löwhagen, T | 1 |
| Beckman, L; Lundgren, E; Rydelius, PA | 1 |
| Brunner, G; Kattermann, R; Sommer, J | 1 |
| Bojan, O; Mustea, I; Preda, N | 1 |
1 review(s) available for leucine and Metastase
| Article | Year |
|---|---|
Carcinoplacental isoenzyme antigens.
Topics: Alkaline Phosphatase; Antigens, Neoplasm; Carcinoembryonic Antigen; Electrophoresis, Starch Gel; Female; HeLa Cells; Hot Temperature; Humans; Isoenzymes; Leucine; Male; Microscopy, Electron; Neoplasm Metastasis; Phenotype; Phenylalanine; Placenta; Placental Extracts; Pregnancy | 1973 |
30 other study(ies) available for leucine and Metastase
| Article | Year |
|---|---|
Inhibition of the proliferation, migration, and invasion of human breast cancer cells by leucine aminopeptidase 3 inhibitors derived from natural marine products.
Topics: Antineoplastic Agents; Biological Products; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Enzyme Inhibitors; Female; Humans; K562 Cells; Leucine; Leucyl Aminopeptidase; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Molecular Docking Simulation; Neoplasm Invasiveness; Neoplasm Metastasis | 2020 |
Leucine-rich diet induces a shift in tumour metabolism from glycolytic towards oxidative phosphorylation, reducing glucose consumption and metastasis in Walker-256 tumour-bearing rats.
Topics: Animals; Carcinoma 256, Walker; Female; Food, Formulated; Glucose; Glycolysis; Leucine; Neoplasm Metastasis; Oxidative Phosphorylation; Rats; Rats, Wistar | 2019 |
Plasma Metabolomic Changes in Mice With Time-restricted Feeding-attenuated Spontaneous Metastasis of Lewis Lung Carcinoma.
Topics: alpha-Tocopherol; Animals; Carcinoma, Lewis Lung; Cholestanol; Cholesterol; Diet, High-Fat; Disease Models, Animal; Docosahexaenoic Acids; Fasting; Humans; Insulin; Isoleucine; Lactic Acid; Leucine; Metabolomics; Mice; Neoplasm Metastasis; Phenylalanine; Pyruvic Acid | 2020 |
TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins.
Topics: Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Calcium; Cathepsins; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Exocytosis; Gene Expression Regulation, Neoplastic; Humans; Leucine; Lung Neoplasms; Lysosomes; Membrane Proteins; Mice; Neoplasm Metastasis; Nerve Tissue Proteins; Prognosis; Protein Isoforms; Proteolysis; Signal Transduction; Survival Analysis; Xenograft Model Antitumor Assays | 2018 |
Discovery of BC-01, a novel mutual prodrug (hybrid drug) of ubenimex and fluorouracil as anticancer agent.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Fluorouracil; Leucine; Mice; Neoplasm Metastasis; Prodrugs; Xenograft Model Antitumor Assays | 2016 |
Protein Intake and Breast Cancer Survival in the Nurses' Health Study.
Topics: Adult; Amino Acids, Branched-Chain; Amino Acids, Essential; Breast Neoplasms; Dietary Proteins; Disease Progression; Energy Metabolism; Female; Humans; Kaplan-Meier Estimate; Leucine; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasm Staging; Nurses; Nutritional Status; Odds Ratio; Proportional Hazards Models; Prospective Studies; Protective Factors; Recommended Dietary Allowances; Risk Assessment; Risk Factors; Time Factors; United States | 2017 |
Overexpression of legumain in tumors is significant for invasion/metastasis and a candidate enzymatic target for prodrug therapy.
Topics: Animals; Antibiotics, Antineoplastic; Biotransformation; Colonic Neoplasms; Cysteine Endopeptidases; Doxorubicin; Enzyme Activation; Enzyme Precursors; Gelatinases; Gene Expression Profiling; Humans; Leucine; Metalloendopeptidases; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Plant Proteins; Prodrugs; RNA, Messenger | 2003 |
ELEVATED SERUM LEUCINE AMINOPEPTIDASE ACTIVITY: CLINICAL SIGNIFICANCE IN PANCREATIC CARCINOMA.
Topics: Aminopeptidases; Clinical Enzyme Tests; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms | 1963 |
THE DIAGNOSTIC VALUE OF SERUM LEUCINE AMINOPEPTIDASE.
Topics: Adolescent; Aminopeptidases; Chemical and Drug Induced Liver Injury; Child; Cholecystitis; Cholelithiasis; Clinical Enzyme Tests; Gallstones; Geriatrics; Hepatitis; Hepatitis A; Jaundice; Jaundice, Obstructive; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms | 1964 |
SPONTANEOUS HYPOGLYCEMIA: DIAGNOSTIC CONSIDERATIONS AND MANAGEMENT.
Topics: Adenoma, Islet Cell; Diabetes Mellitus; Diagnosis, Differential; Humans; Hypoglycemia; Leucine; Malingering; Neoplasm Metastasis; Pancreatic Neoplasms; Surgical Procedures, Operative; Tolbutamide | 1964 |
CLINICAL AND BIOCHEMICAL STUDIES IN PATIENTS WITH FUNCTIONING ISLET CELL TUMORS.
Topics: Adenoma, Islet Cell; Amino Acids; Biochemical Phenomena; Biochemistry; Biomedical Research; Carbohydrate Metabolism; Glucose; Glucose Tolerance Test; Glutarates; Humans; Hypoglycemia; Insulin; Isoleucine; Leucine; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Research; Valine | 1964 |
Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition.
Topics: Animals; Cattle; Chymotrypsin; Crystallography, X-Ray; Escherichia coli; Factor VIIa; Fibrinolysin; Glycoproteins; Humans; Leucine; Models, Molecular; Neoplasm Metastasis; Oxygen; Phenylalanine; Protease Inhibitors; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Static Electricity; Trypsin | 2005 |
Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Bone Neoplasms; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Citrus; Female; Galectin 3; Humans; Leucine; Lung Neoplasms; Male; Mice; Mice, Inbred ICR; Mice, SCID; Neoplasm Metastasis; Neoplasm Transplantation; Pectins; Prostatic Neoplasms | 2005 |
Incadronate inhibits aminopeptidase N expression in prostatic PC-3 cells.
Topics: Antineoplastic Agents; Bone and Bones; Bone Density Conservation Agents; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Cytosol; Diphosphonates; Enzyme Inhibitors; Humans; Leucine; Male; Mevalonic Acid; Neoplasm Invasiveness; Neoplasm Metastasis; rap1 GTP-Binding Proteins | 2006 |
Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Female; Humans; Leucine; Lung Neoplasms; Lysine; Male; Membrane Potentials; Mice; Mice, SCID; Neoplasm Metastasis; Peptides; Phosphatidylserines; Prostate-Specific Antigen; Prostatic Neoplasms; Xenograft Model Antitumor Assays | 2006 |
Phagocytosis and solubilization of fixed cells by metastatic hamster embryo fibroblasts, Nil2C2.
Topics: Animals; Autoradiography; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cricetinae; Embryo, Mammalian; Leucine; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Microscopy, Electron; Neoplasm Metastasis; Phagocytosis; Salmonella typhimurium; Solubility; Tritium | 1984 |
[Effect of bestatin on immuno-suppressive acidic protein in patients with stomach cancer].
Topics: Adjuvants, Immunologic; Adult; Aged; Female; Humans; Leucine; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Staging; Stomach Neoplasms | 1984 |
Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein. An antigen associated with metastasis contains leucine-rich repeats.
Topics: Amino Acid Sequence; Antigens, Neoplasm; Base Sequence; Biomarkers, Tumor; Chromosome Mapping; Chromosomes, Human, Pair 6; Cloning, Molecular; Consensus Sequence; DNA Primers; DNA, Complementary; Gene Expression; Humans; Leucine; Membrane Glycoproteins; Molecular Sequence Data; Neoplasm Metastasis; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Trophoblasts | 1994 |
Inhibition of human breast cancer metastasis in nude mice by synthetic glycoamines.
Topics: Amino Acids; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Drug Screening Assays, Antitumor; Female; Glycoconjugates; Humans; Lectins; Leucine; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Peanut Agglutinin; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs.
Topics: Affinity Labels; Animals; Binding Sites; Cathepsin B; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Electrophoresis, Polyacrylamide Gel; Humans; Indicators and Reagents; Iodine Radioisotopes; Isotope Labeling; Kinetics; Leucine; Lysosomes; Mice; Mice, Inbred BALB C; Mice, Knockout; Neoplasm Metastasis; Substrate Specificity | 2000 |
Inhibition of endosomal insulin-like growth factor-I processing by cysteine proteinase inhibitors blocks receptor-mediated functions.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Blotting, Western; Cell Membrane; Chromatography, High Pressure Liquid; Cysteine Proteinase Inhibitors; Dipeptides; DNA; Dose-Response Relationship, Drug; Endosomes; Female; Flow Cytometry; Humans; Insulin-Like Growth Factor I; Kinetics; Leucine; Ligands; Liver; Male; Mice; Models, Biological; Neoplasm Metastasis; Phosphorylation; Precipitin Tests; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Time Factors; Tumor Cells, Cultured; Tyrosine | 2001 |
A comparison of canine normal hepatic alkaline phosphatase and variant alkaline phosphatase of serum and liver.
Topics: Adrenal Cortex Diseases; Adrenal Cortex Hormones; Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Dogs; Drug Stability; Enzyme Induction; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Leucine; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Neoplasm Metastasis; Phenylalanine; Time Factors | 1975 |
Chemoimmunotherapy with cyclophosphamide and bestatin in experimental metastasis in mice.
Topics: Adjuvants, Immunologic; Animals; Combined Modality Therapy; Cyclophosphamide; Cytotoxicity, Immunologic; Immunity, Cellular; Killer Cells, Natural; Leucine; Lymphoma; Macrophages; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms, Experimental | 1989 |
Immunomodulatory and therapeutic properties of bestatin in mice.
Topics: Adjuvants, Immunologic; Animals; Cytotoxicity, Immunologic; Immunity, Cellular; Immunity, Innate; Killer Cells, Natural; Leucine; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Macrophage Activation; Mice; Neoplasm Metastasis; Neoplasms, Experimental | 1986 |
Selective inhibition of proteolytic enzymes in an in vivo mouse model for experimental metastasis.
Topics: Animals; Cathepsin B; Cathepsins; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Endopeptidases; Female; Fibrinolysis; Leucine; Leupeptins; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Peptide Hydrolases; Plasminogen Activators; Plasminogen Inactivators; Protease Inhibitors; Serine Endopeptidases; Thrombin; Thrombosis | 1986 |
Planning the appropriate operations for islet cell tumors of the pancreas.
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Glucose Tolerance Test; Humans; Leucine; Neoplasm Metastasis; Pancreatic Neoplasms; Radionuclide Imaging; Tolbutamide | 1970 |
The formation of thyroglobulin in human thyroid medullary carcinoma.
Topics: Ammonium Sulfate; Carcinoma; Centrifugation, Density Gradient; Chemical Precipitation; Humans; In Vitro Techniques; Iodine Radioisotopes; Leucine; Neoplasm Metastasis; Proteins; Thyroglobulin; Thyroid Neoplasms; Tritium | 1973 |
Amino acid naphthylamidase isozymes in cancer cells and normal cells.
Topics: Aged; Aminopeptidases; Autopsy; Cell Line; Cells, Cultured; Copper; Electrophoresis; Female; Gels; Humans; Isoenzymes; Leucine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Middle Aged; Naphthalenes; Neoplasm Metastasis; Neoplasms; Starch; Tissue Extracts | 1971 |
[On the behavior of the so-called leucine aminopeptidase (LAP) in the serum during the application of various substrates].
Topics: Adolescent; Adult; Aged; Animals; Aspartate Aminotransferases; Biliary Tract Diseases; Cholestasis; Female; Glycine; Humans; Leucine; Leucyl Aminopeptidase; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Myocardial Infarction; Neoplasm Metastasis; Pancreatic Neoplasms; Rats | 1968 |
[Modification of some free amino acids in the serum of cancer patients under the influence of glucose on tumoral metabolism].
Topics: Alanine; Amino Acids; Breast Neoplasms; Chromatography, Paper; Dietary Carbohydrates; Dietary Proteins; Female; Gastrointestinal Neoplasms; Glucose; Glycolysis; Leucine; Lung Neoplasms; Lysine; Neoplasm Metastasis; Perfusion; Stimulation, Chemical; Uterine Neoplasms; Valine | 1969 |