leucine and Metastase

leucine has been researched along with Metastase in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199016 (51.61)18.7374
1990's2 (6.45)18.2507
2000's7 (22.58)29.6817
2010's4 (12.90)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Dai, G; Fang, C; Guo, L; Guo, S; Song, W; Wang, S; Wang, X; Wei, L; Yang, H; Zhang, H; Zhang, L; Zhao, X; Zhao, Y1
Brunetto, SQ; Busanello, ENB; Castelucci, BG; Consonni, SR; de Oliveira, AG; Gomes-Marcondes, MCC; Lima, TI; Machado, G; Marques, AC; Ramos, CD; Silveira, LR; Tobar, N; Vercesi, AE; Viana, LR1
Picklo, MJ; Rust, BM; Yan, L1
Creighton, CJ; Fradette, JJ; Gibbons, DL; Gibson, LA; Grzeskowiak, CL; Kundu, ST; Rodriguez, LB; Scott, KL1
Hou, J; Huang, Y; Jia, Y; Jiang, Y; Li, X; Wang, X; Xu, W; Zhang, J; Zhang, Y; Zou, M1
Chen, WY; Hankinson, SE; Holmes, MD; Tamimi, RM; Wang, J1
Edgington, T; Huang, H; Janda, K; Liu, C; Sun, C1
EVERSOLE, JW; MOSELEY, T1
ANAGNOSTOU, E; HADZIYANNIS, S; KAKARI, S; MERICAS, G1
SCHOLTZ, DA1
FIELD, JB1
Bajaj, SP; Cascio, D; Chand, HS; Kisiel, W; Schmidt, AE1
Glinskii, OV; Glinsky, GV; Glinsky, VV; Huxley, VH; Pienta, KJ; Raz, A1
Hirano, K; Iguchi, K; Nakano, T; Usui, S1
Degani, H; Eshhar, Z; Kalchenko, V; Makovitzki, A; Papo, N; Seger, D; Shai, Y1
Nishimura, K; Nishino, Y; Noda, Y; Otsu, H; Sakiyama, H1
Habu, H; Hoshi, K; Ishii, T; Sunagawa, M; Takeshita, K1
Cheater, AJ; Davison, MD; Myers, KA; Rahi-Saund, V; Stern, PL; Young, JA1
Glinsky, GV; Glinsky, VV; Kiriakova, G; Metcalf, JB; Mossine, VV; Price, JE1
Bellingard-Dubouchaud, V; Bogyo, M; Greenbaum, D; Toba, S; Verhelst, S1
Authier, F; Bergeron, JJ; Brodt, P; Chevet, E; Di Guglielmo, GM; Navab, R1
Dorner, JL; Hoffmann, WE1
Abe, F; Black, PL; Schneider, M; Talmadge, JE1
Lenz, BF; Long, C; Pennington, R; Phillips, H; Schneider, M; Talmadge, JE; Tribble, H1
Ahsan, A; Bain, DL; Ostrowski, LE; Pagast, P; Patel, A; Schultz, RM; Suthar, BP; Wong, C1
DePeyster, FA1
Fishman, WH1
Hjern, B; Ljunggren, JG; Löwhagen, T1
Beckman, L; Lundgren, E; Rydelius, PA1
Brunner, G; Kattermann, R; Sommer, J1
Bojan, O; Mustea, I; Preda, N1

Reviews

1 review(s) available for leucine and Metastase

ArticleYear
Carcinoplacental isoenzyme antigens.
    Advances in enzyme regulation, 1973, Volume: 11

    Topics: Alkaline Phosphatase; Antigens, Neoplasm; Carcinoembryonic Antigen; Electrophoresis, Starch Gel; Female; HeLa Cells; Hot Temperature; Humans; Isoenzymes; Leucine; Male; Microscopy, Electron; Neoplasm Metastasis; Phenotype; Phenylalanine; Placenta; Placental Extracts; Pregnancy

1973

Other Studies

30 other study(ies) available for leucine and Metastase

ArticleYear
Inhibition of the proliferation, migration, and invasion of human breast cancer cells by leucine aminopeptidase 3 inhibitors derived from natural marine products.
    Anti-cancer drugs, 2020, Volume: 31, Issue:1

    Topics: Antineoplastic Agents; Biological Products; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Enzyme Inhibitors; Female; Humans; K562 Cells; Leucine; Leucyl Aminopeptidase; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Molecular Docking Simulation; Neoplasm Invasiveness; Neoplasm Metastasis

2020
Leucine-rich diet induces a shift in tumour metabolism from glycolytic towards oxidative phosphorylation, reducing glucose consumption and metastasis in Walker-256 tumour-bearing rats.
    Scientific reports, 2019, 10-29, Volume: 9, Issue:1

    Topics: Animals; Carcinoma 256, Walker; Female; Food, Formulated; Glucose; Glycolysis; Leucine; Neoplasm Metastasis; Oxidative Phosphorylation; Rats; Rats, Wistar

2019
Plasma Metabolomic Changes in Mice With Time-restricted Feeding-attenuated Spontaneous Metastasis of Lewis Lung Carcinoma.
    Anticancer research, 2020, Volume: 40, Issue:4

    Topics: alpha-Tocopherol; Animals; Carcinoma, Lewis Lung; Cholestanol; Cholesterol; Diet, High-Fat; Disease Models, Animal; Docosahexaenoic Acids; Fasting; Humans; Insulin; Isoleucine; Lactic Acid; Leucine; Metabolomics; Mice; Neoplasm Metastasis; Phenylalanine; Pyruvic Acid

2020
TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins.
    Nature communications, 2018, 07-16, Volume: 9, Issue:1

    Topics: Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Calcium; Cathepsins; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Exocytosis; Gene Expression Regulation, Neoplastic; Humans; Leucine; Lung Neoplasms; Lysosomes; Membrane Proteins; Mice; Neoplasm Metastasis; Nerve Tissue Proteins; Prognosis; Protein Isoforms; Proteolysis; Signal Transduction; Survival Analysis; Xenograft Model Antitumor Assays

2018
Discovery of BC-01, a novel mutual prodrug (hybrid drug) of ubenimex and fluorouracil as anticancer agent.
    European journal of medicinal chemistry, 2016, Oct-04, Volume: 121

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Fluorouracil; Leucine; Mice; Neoplasm Metastasis; Prodrugs; Xenograft Model Antitumor Assays

2016
Protein Intake and Breast Cancer Survival in the Nurses' Health Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, 01-20, Volume: 35, Issue:3

    Topics: Adult; Amino Acids, Branched-Chain; Amino Acids, Essential; Breast Neoplasms; Dietary Proteins; Disease Progression; Energy Metabolism; Female; Humans; Kaplan-Meier Estimate; Leucine; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasm Staging; Nurses; Nutritional Status; Odds Ratio; Proportional Hazards Models; Prospective Studies; Protective Factors; Recommended Dietary Allowances; Risk Assessment; Risk Factors; Time Factors; United States

2017
Overexpression of legumain in tumors is significant for invasion/metastasis and a candidate enzymatic target for prodrug therapy.
    Cancer research, 2003, Jun-01, Volume: 63, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Biotransformation; Colonic Neoplasms; Cysteine Endopeptidases; Doxorubicin; Enzyme Activation; Enzyme Precursors; Gelatinases; Gene Expression Profiling; Humans; Leucine; Metalloendopeptidases; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Plant Proteins; Prodrugs; RNA, Messenger

2003
ELEVATED SERUM LEUCINE AMINOPEPTIDASE ACTIVITY: CLINICAL SIGNIFICANCE IN PANCREATIC CARCINOMA.
    The American surgeon, 1963, Volume: 29

    Topics: Aminopeptidases; Clinical Enzyme Tests; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms

1963
THE DIAGNOSTIC VALUE OF SERUM LEUCINE AMINOPEPTIDASE.
    Journal of clinical pathology, 1964, Volume: 17

    Topics: Adolescent; Aminopeptidases; Chemical and Drug Induced Liver Injury; Child; Cholecystitis; Cholelithiasis; Clinical Enzyme Tests; Gallstones; Geriatrics; Hepatitis; Hepatitis A; Jaundice; Jaundice, Obstructive; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms

1964
SPONTANEOUS HYPOGLYCEMIA: DIAGNOSTIC CONSIDERATIONS AND MANAGEMENT.
    Arizona medicine, 1964, Volume: 21

    Topics: Adenoma, Islet Cell; Diabetes Mellitus; Diagnosis, Differential; Humans; Hypoglycemia; Leucine; Malingering; Neoplasm Metastasis; Pancreatic Neoplasms; Surgical Procedures, Operative; Tolbutamide

1964
CLINICAL AND BIOCHEMICAL STUDIES IN PATIENTS WITH FUNCTIONING ISLET CELL TUMORS.
    The American journal of medicine, 1964, Volume: 36

    Topics: Adenoma, Islet Cell; Amino Acids; Biochemical Phenomena; Biochemistry; Biomedical Research; Carbohydrate Metabolism; Glucose; Glucose Tolerance Test; Glutarates; Humans; Hypoglycemia; Insulin; Isoleucine; Leucine; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Research; Valine

1964
Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition.
    The Journal of biological chemistry, 2005, Jul-29, Volume: 280, Issue:30

    Topics: Animals; Cattle; Chymotrypsin; Crystallography, X-Ray; Escherichia coli; Factor VIIa; Fibrinolysin; Glycoproteins; Humans; Leucine; Models, Molecular; Neoplasm Metastasis; Oxygen; Phenylalanine; Protease Inhibitors; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Static Electricity; Trypsin

2005
Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:5

    Topics: Animals; Antibodies; Antibodies, Monoclonal; Bone Neoplasms; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Citrus; Female; Galectin 3; Humans; Leucine; Lung Neoplasms; Male; Mice; Mice, Inbred ICR; Mice, SCID; Neoplasm Metastasis; Neoplasm Transplantation; Pectins; Prostatic Neoplasms

2005
Incadronate inhibits aminopeptidase N expression in prostatic PC-3 cells.
    Cancer letters, 2006, Jun-18, Volume: 237, Issue:2

    Topics: Antineoplastic Agents; Bone and Bones; Bone Density Conservation Agents; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Cytosol; Diphosphonates; Enzyme Inhibitors; Humans; Leucine; Male; Mevalonic Acid; Neoplasm Invasiveness; Neoplasm Metastasis; rap1 GTP-Binding Proteins

2006
Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide.
    Cancer research, 2006, May-15, Volume: 66, Issue:10

    Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Female; Humans; Leucine; Lung Neoplasms; Lysine; Male; Membrane Potentials; Mice; Mice, SCID; Neoplasm Metastasis; Peptides; Phosphatidylserines; Prostate-Specific Antigen; Prostatic Neoplasms; Xenograft Model Antitumor Assays

2006
Phagocytosis and solubilization of fixed cells by metastatic hamster embryo fibroblasts, Nil2C2.
    Cancer research, 1984, Volume: 44, Issue:5

    Topics: Animals; Autoradiography; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cricetinae; Embryo, Mammalian; Leucine; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Microscopy, Electron; Neoplasm Metastasis; Phagocytosis; Salmonella typhimurium; Solubility; Tritium

1984
[Effect of bestatin on immuno-suppressive acidic protein in patients with stomach cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8

    Topics: Adjuvants, Immunologic; Adult; Aged; Female; Humans; Leucine; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Staging; Stomach Neoplasms

1984
Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein. An antigen associated with metastasis contains leucine-rich repeats.
    The Journal of biological chemistry, 1994, Mar-25, Volume: 269, Issue:12

    Topics: Amino Acid Sequence; Antigens, Neoplasm; Base Sequence; Biomarkers, Tumor; Chromosome Mapping; Chromosomes, Human, Pair 6; Cloning, Molecular; Consensus Sequence; DNA Primers; DNA, Complementary; Gene Expression; Humans; Leucine; Membrane Glycoproteins; Molecular Sequence Data; Neoplasm Metastasis; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Trophoblasts

1994
Inhibition of human breast cancer metastasis in nude mice by synthetic glycoamines.
    Cancer research, 1996, Dec-01, Volume: 56, Issue:23

    Topics: Amino Acids; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Drug Screening Assays, Antitumor; Female; Glycoconjugates; Humans; Lectins; Leucine; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Peanut Agglutinin; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Stem Cell Assay

1996
Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs.
    Chemistry & biology, 2000, Volume: 7, Issue:1

    Topics: Affinity Labels; Animals; Binding Sites; Cathepsin B; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Electrophoresis, Polyacrylamide Gel; Humans; Indicators and Reagents; Iodine Radioisotopes; Isotope Labeling; Kinetics; Leucine; Lysosomes; Mice; Mice, Inbred BALB C; Mice, Knockout; Neoplasm Metastasis; Substrate Specificity

2000
Inhibition of endosomal insulin-like growth factor-I processing by cysteine proteinase inhibitors blocks receptor-mediated functions.
    The Journal of biological chemistry, 2001, Apr-27, Volume: 276, Issue:17

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Blotting, Western; Cell Membrane; Chromatography, High Pressure Liquid; Cysteine Proteinase Inhibitors; Dipeptides; DNA; Dose-Response Relationship, Drug; Endosomes; Female; Flow Cytometry; Humans; Insulin-Like Growth Factor I; Kinetics; Leucine; Ligands; Liver; Male; Mice; Models, Biological; Neoplasm Metastasis; Phosphorylation; Precipitin Tests; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Time Factors; Tumor Cells, Cultured; Tyrosine

2001
A comparison of canine normal hepatic alkaline phosphatase and variant alkaline phosphatase of serum and liver.
    Clinica chimica acta; international journal of clinical chemistry, 1975, Jul-09, Volume: 62, Issue:1

    Topics: Adrenal Cortex Diseases; Adrenal Cortex Hormones; Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Dogs; Drug Stability; Enzyme Induction; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Leucine; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Neoplasm Metastasis; Phenylalanine; Time Factors

1975
Chemoimmunotherapy with cyclophosphamide and bestatin in experimental metastasis in mice.
    Cancer immunology, immunotherapy : CII, 1989, Volume: 29, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Combined Modality Therapy; Cyclophosphamide; Cytotoxicity, Immunologic; Immunity, Cellular; Killer Cells, Natural; Leucine; Lymphoma; Macrophages; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms, Experimental

1989
Immunomodulatory and therapeutic properties of bestatin in mice.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: Adjuvants, Immunologic; Animals; Cytotoxicity, Immunologic; Immunity, Cellular; Immunity, Innate; Killer Cells, Natural; Leucine; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Macrophage Activation; Mice; Neoplasm Metastasis; Neoplasms, Experimental

1986
Selective inhibition of proteolytic enzymes in an in vivo mouse model for experimental metastasis.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Animals; Cathepsin B; Cathepsins; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Endopeptidases; Female; Fibrinolysis; Leucine; Leupeptins; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Peptide Hydrolases; Plasminogen Activators; Plasminogen Inactivators; Protease Inhibitors; Serine Endopeptidases; Thrombin; Thrombosis

1986
Planning the appropriate operations for islet cell tumors of the pancreas.
    The Surgical clinics of North America, 1970, Volume: 50, Issue:1

    Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Glucose Tolerance Test; Humans; Leucine; Neoplasm Metastasis; Pancreatic Neoplasms; Radionuclide Imaging; Tolbutamide

1970
The formation of thyroglobulin in human thyroid medullary carcinoma.
    Acta endocrinologica, 1973, Volume: 74, Issue:1

    Topics: Ammonium Sulfate; Carcinoma; Centrifugation, Density Gradient; Chemical Precipitation; Humans; In Vitro Techniques; Iodine Radioisotopes; Leucine; Neoplasm Metastasis; Proteins; Thyroglobulin; Thyroid Neoplasms; Tritium

1973
Amino acid naphthylamidase isozymes in cancer cells and normal cells.
    Clinical genetics, 1971, Volume: 2, Issue:1

    Topics: Aged; Aminopeptidases; Autopsy; Cell Line; Cells, Cultured; Copper; Electrophoresis; Female; Gels; Humans; Isoenzymes; Leucine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Middle Aged; Naphthalenes; Neoplasm Metastasis; Neoplasms; Starch; Tissue Extracts

1971
[On the behavior of the so-called leucine aminopeptidase (LAP) in the serum during the application of various substrates].
    Klinische Wochenschrift, 1968, May-15, Volume: 46, Issue:10

    Topics: Adolescent; Adult; Aged; Animals; Aspartate Aminotransferases; Biliary Tract Diseases; Cholestasis; Female; Glycine; Humans; Leucine; Leucyl Aminopeptidase; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Myocardial Infarction; Neoplasm Metastasis; Pancreatic Neoplasms; Rats

1968
[Modification of some free amino acids in the serum of cancer patients under the influence of glucose on tumoral metabolism].
    Clinica chimica acta; international journal of clinical chemistry, 1969, Volume: 23, Issue:2

    Topics: Alanine; Amino Acids; Breast Neoplasms; Chromatography, Paper; Dietary Carbohydrates; Dietary Proteins; Female; Gastrointestinal Neoplasms; Glucose; Glycolysis; Leucine; Lung Neoplasms; Lysine; Neoplasm Metastasis; Perfusion; Stimulation, Chemical; Uterine Neoplasms; Valine

1969