leucine has been researched along with Liver Neoplasms in 172 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 138 (80.23) | 18.7374 |
1990's | 10 (5.81) | 18.2507 |
2000's | 6 (3.49) | 29.6817 |
2010's | 11 (6.40) | 24.3611 |
2020's | 7 (4.07) | 2.80 |
Authors | Studies |
---|---|
Hou, X; Jia, G; Jiang, Y; Li, P; Li, X; Tan, L; Wang, X; Xu, W; Yue, K; Zhang, J; Zhang, L; Zhang, Z | 1 |
Cheng, X; Guo, Z; He, M; Huang, L; Liu, Z; Lu, X; Ma, T; Peng, W; Tang, F; Tian, S; Tu, F; Wang, X; Wu, Y; Xu, X; Yang, J; Ye, J; Zeng, X; Zhang, L; Zhang, P; Zou, J | 1 |
Kim, B; Park, C; Park, T | 1 |
Chen, JY; He, Y; Li, YJ; Liu, CH; Lu, Y; Song, ZJ; Wang, YL; Zhu, XQ | 1 |
Hirayama, A; Ikemoto, T; Imura, S; Kinoshita, S; Morine, Y; Saito, Y; Shimada, M; Tanaka, Y; Utsunomiya, T; Yamada, S; Yamanaka-Okumura, H | 1 |
Chung, RT; Holmes, JA | 1 |
Bondin, M; Brown, A; Burroughs, M; Chayama, K; Dylla, DE; Emmett, A; Feld, JJ; Forns, X; Gordon, SC; Heo, J; Hou, J; Jacobson, IM; Lampertico, P; Marcinak, J; Pol, S; Tatsch, F; Zhang, Z | 1 |
Dou, C; Fang, C; Fu, X; Li, D; Liu, H; Liu, Z; Wang, H; Wang, X; Wu, H; Xu, W; Zhang, J; Zhang, Y; Zhao, Y; Zhu, D | 1 |
Aida, T; Akiyama, Y; Arii, S; Ban, D; Kudo, A; Mitsunori, Y; Mizuno, Y; Ogawa, K; Ono, H; Shimada, S; Tanabe, M; Tanaka, S; Watanabe, S; Yamaoka, S | 1 |
Cao, J; Ding, Q; Gao, Q; Gao, S; Kong, X; Liang, X; Ma, C; Wang, B; Xu, W; Yan, Y; Zang, J; Zhang, Y; Zhao, C | 1 |
Liu, S; Su, M; Wei, M; Zhou, Z | 1 |
Li, Y; Liu, XJ; Wu, SY; Zhen, YS; Zheng, YB | 1 |
Cao, J; Huang, Y; Li, Y; Liang, X; Ma, C; Wu, P; Xu, W; Zhang, Y | 1 |
Dai, G; Duan, Y; Shi, LH; Sun, ZP; Wang, XJ; Xu, WF; Zhang, J; Zhang, XR | 1 |
Asaoka, T; Doki, Y; Eguchi, H; Gotoh, K; Kawamoto, K; Mori, M; Noda, T; Ogawa, H; Umeshita, K; Wada, H; Yamada, D; Yamashita, M | 1 |
Ali, R; Duan, C; Gupta, MB; Han, VK; Kamei, H; Khosravi, JM; Liu, S; Nazarian, S; Seferovic, MD | 1 |
Bukh, J; Ghanem, L; Gottwein, JM; Jensen, TB; Scheel, TK | 1 |
Kaneoka, Y; Kumada, T; Maeda, A; Toyoda, H | 1 |
Bäuerl, C; Blaas, PM; Mach, L; Mikula, M; Mikulits, W; Ng, KM; Nimmerfall, E; Puxbaum, V; Taub, N; Wieser, J; Yeoh, GC | 1 |
Cao, X; Ma, J; Novotny-Diermayr, V; Tan, AL; Zhang, T | 1 |
BARDAWILL, C; CHANG, C | 1 |
EVERSOLE, JW; MOSELEY, T | 1 |
AFZELIUS, BA; ARRHENIUS, E; GUSTAFSSON, RG; MUKHERJEE, T | 1 |
BAUER, JM; WU, C | 1 |
GREEN, JB | 1 |
HARTJE, J; OEHLERT, W | 1 |
FEO, F; GABRIEL, L; GRAVELA, E; TERRANOVA, T | 1 |
ANAGNOSTOU, E; HADZIYANNIS, S; KAKARI, S; MERICAS, G | 1 |
BASSI, R; GUANTI, G; SALONNA, L; TRIGGIANI, G | 1 |
MANDEL, P | 1 |
LORINCZ, AB; RYAN, WL | 1 |
FIELD, JB | 1 |
CIARANFI, E; FONNESU, A; GUIDOTTI, GG | 1 |
BLOEMENDAL, H; BONT, WS; BOSCH, L | 1 |
FISCHL, J; PRUZANSKI, W | 1 |
GINSBERG, DM | 1 |
CLARKE, DW; EHRLICH, R; EVANS, J; FORBATH, N; VOLPE, R | 1 |
GRECO, AE; MAVER, ME | 1 |
Kojima, H; Kunimoto, H; Nakajima, K; Nakajima, R; Sasaki, T; Zhao, H | 1 |
Heo, YS; Hwang, SH; Kwon, OJ; Lim, YS; Oh, HB | 1 |
Aoyagi, Y; Ichida, F; Odani, S; Ogata, K; Ono, T; Takahashi, Y | 1 |
Almersjö, O; Gustavsson, B; Hasselgren, PO; Rosengren, K | 1 |
Faquin, WC; Goldberg, MA; Schneider, TJ | 1 |
Lei, KY; Wang, Y; Zhang, JJ | 1 |
Eremin, O; Garlick, PJ; Heys, SD; McNurlan, MA; Park, KG | 1 |
Bode, BP; Souba, WW; Wasa, M | 1 |
Ginsberg, HN; Jiang, H; Shang, A; Wu, X | 1 |
Brandt-Rauf, PW; Chen, JM; Marion, MJ; Pincus, MR; Smith, SJ | 1 |
Bode, BP; Pawlik, TM; Souba, WW; Sweeney, TJ | 1 |
Dong, X; Ekström, U; Nilsson-Ehle, P; Xu, N; Ye, Q; Zhang, XY | 1 |
Hirano, K; Ito, Y; Sasaki, M; Sawaki, S; Sugiura, M | 1 |
Bannon, M; Busch, H; Crooke, ST; Sitz, TO | 1 |
Endo, Y; Kanai, K; Kaneko, Y; Oda, T | 1 |
Ichihara, A | 2 |
Kanatani, M; Kojima, J; Nakamura, N; Tateishi, R; Yamamoto, T | 1 |
Coetzee, ML; Dolan, ML; Ove, P; Spangler, M | 2 |
Colten, HR; Strunk, RC; Tashjian, AH | 1 |
Ballard, FJ; Gunn, JM; Hanson, RW; Reshef, L; Tilghman, SM | 1 |
Ballard, FJ; Knowles, SE | 1 |
Bourrillon, R; Moreau-Gachelin, F | 1 |
Katunuma, N; Kobayashi, K; Morris, HP | 1 |
Cochran, RA; Ledford, BE; Warner, RW | 1 |
Beaven, MA; De Mello, MC; Hial, V; Horakova, Z | 1 |
Goto, M; Ichihara, A; Shinno, H | 1 |
Agostini, C | 1 |
Levinson, BB; Steinberg, RA; Tomkins, GM | 1 |
Dorner, JL; Hoffmann, WE | 1 |
Kolarov, J; Krempaský, V; Kuzela, S; Ujházy, V | 1 |
Anghileri, LJ; Heidbreder, M | 1 |
Brunda, MJ; Ferguson, HR; Minden, P | 1 |
Chu, C; Mirvish, SS | 1 |
Arima, T; Fujii, S; Niinobe, M; Okuda, H; Tamura, Y | 1 |
Bhargava, PM; Bornecque, CA; Szafarz, D; Zajdela, F | 1 |
Delhaye, M; Galand, P; Gulbis, B; Mairesse, N | 1 |
Adler, R; Galun, E; Hurwitz, E; Sela, M; Shahaar, M; Shouval, D; Wilchek, M | 1 |
O'Keefe, SJ; Ogden, J; Ramjee, G; Rund, J | 1 |
Hortin, GL | 1 |
Begley, JA; Green-Colligan, PD; Hall, CA | 1 |
Danko, IM; Korotkoruchko, VP | 1 |
Cihák, A; Pitot, HC; Weiss, JW | 1 |
Boctor, A; Grossman, A | 1 |
Fritz, JE; Kenney, FT; Lee, KL; Stiles, CD | 1 |
Barker, KL; Kenney, FT; Lee, KL | 2 |
Emanuel, JR; Gelehrter, TD | 1 |
Albert, Z; Szewczuk, A | 1 |
Becker, JE; Bushnell, DE; Potter, VR; Yager, JD | 1 |
Blomberg, F; Perlmann, P; Raftell, M | 1 |
Gelboin, HV; Miller, H; Whitlock, JP | 1 |
Beck, G; Beck, JP; Bollack, C | 1 |
Potter, VR; Webb, TE | 1 |
Boutwell, RK; Morris, HP; Potter, VR; Schreiber, G | 1 |
Busch, H; Nakamura, T; Prestayko, AW | 1 |
Uehleke, H | 1 |
Weinstein, IB | 1 |
Arora, DJ; de Lamirande, G | 1 |
Grossman, A; Lele, KP; Levy, M; Schenkein, I; Sheldon, J | 1 |
Henshaw, EC; Hiatt, HH; Hirsch, CA; Milosevic, F | 1 |
Lesch, R; Maeno, H; Rotermund, HM; Schreiber, G; Weigand, K | 1 |
Rizzo, AJ; Webb, TE | 1 |
Akino, T; Amano, M; Mitsui, H | 1 |
Hancock, RL; Rennert, OM | 1 |
Akino, T; Amano, M | 2 |
Maeno, H; Rotermund, HM; Schreiber, G; Weigand, K; Weinssen, U | 1 |
Dickson, JA | 1 |
Chen, CC; Kao, WY; Lin, JY; Tserng, KY; Tung, TC | 1 |
Agostini, C; Comi, P | 2 |
Ichihara, A; Ogawa, K; Yokojima, A | 1 |
Shimizu, T | 2 |
Estensen, RD | 1 |
Corbascio, AN; Ishii, DN | 1 |
Rennert, OM | 1 |
Sarma, DS; Sidransky, H; Verney, E | 1 |
Bachellerie, JP; Martin-Prevel, C; Zalta, JP | 2 |
Jackson, SH | 1 |
Chandrasekhara, N; Narayan, KA | 1 |
Lee, JC | 1 |
Taylor, MW; Volkers, SA | 1 |
Inoue, H; Kaplan, JH; Pitot, HC | 1 |
Arnaboldi, A; Ciaranfi, E; Perin, A; Scalabrino, G; Sessa, A | 1 |
Higashi, T; Kashiwagi, K; Tobe, T | 1 |
Agostini, C; Comi, P; Mortara, G | 1 |
Higashi, T; Kashiwagi, K; Tobe, T; Warabioka, K | 1 |
Kuff, EL; Miller, JV; Thompson, EB; Wilson, SH | 1 |
Hashinotsume, M; Higashino, K; Yamamura, Y | 2 |
Kartenbeck, J; Müller, M; Schreiber, G; Schreiber, M | 2 |
Irvin, JL; Jones, RB | 1 |
Castagna, M; Chauveau, J; Hamon, G | 1 |
Kartenbeck, J; Lesch, R; Schreiber, G; Timko, J; Urban, J; Zimber, P | 1 |
Blomberg, F; Raftell, M | 1 |
Morris, HP; Narayan, KA | 2 |
Arnold, EA; Buksas, MM; Young, KE | 1 |
Moyer, GH; Pitot, HC | 2 |
Kolarov, J; Krempaský, V; Kuzela, S | 1 |
Schreiber, G; Urban, J; Zimber, P | 1 |
Hogan, BL; Murden, S | 1 |
Endo, Y; Kanai, K; Oda, T; Tanaka, N | 1 |
Kartenbeck, J; Schreiber, G; Schreiber, M | 1 |
Hogan, BL; McIlhinney, A | 1 |
Dunaway, GA; Morris, HP; Trahan, LJ; Weber, G | 1 |
Roberts, J; Schmid, FA; Takai, K | 1 |
Bonner, J; Garrard, WT | 1 |
Dybing, E | 1 |
Higashino, K; Kudo, S; Yamamura, Y | 1 |
Curran, JF; Thompson, EB; Tomkins, GM | 1 |
Kenney, FT; Reel, JR | 1 |
Auricchio, F; Martin, D; Tompkins, G | 1 |
Kenney, FT; Lee, KL; Reel, JR | 1 |
Levitan, IB; Morris, HP; Webb, TE | 1 |
Levinson, BB; Stellwagen, RH; Tomkins, GM | 1 |
Barnett, CA; Wicks, WD | 1 |
Kenney, FT; Lee, KL | 1 |
McKibbin, JB; Wicks, WD | 1 |
Kenney, FT; Lee, KL; Stiles, CD | 1 |
Higashi, T | 1 |
Ogawa, K | 1 |
Kattermann, R; Schlaeger, R | 1 |
Beckman, L; Lundgren, E; Rydelius, PA | 1 |
Bouhunická, E; Krempaský, V; Ujházy, V; Whisson, ME | 1 |
Brunner, G; Kattermann, R; Sommer, J | 1 |
Izawa, M; Kawashima, K | 1 |
4 review(s) available for leucine and Liver Neoplasms
Article | Year |
---|---|
New approaches in viraemic organ transplantation and antiviral therapies.
Topics: Aminoisobutyric Acids; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Cyclopropanes; Guanine; Hepatitis B, Chronic; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Lactams, Macrocyclic; Leucine; Liver Neoplasms; Liver Transplantation; Macrocyclic Compounds; Proline; Quinoxalines; Salvage Therapy; Sofosbuvir; Sulfonamides; Tenofovir; Transplants | 2020 |
HYPOGLYCEMIA ASSOCIATED WITH EXTRAPANCREATIC NEOPLASMS, WITH A NOTE ON OTHER UNUSUAL FORMS OF HYPOGLYCEMIA.
Topics: Adrenogenital Syndrome; Carcinoma, Hepatocellular; Drug Therapy; Glycogen Storage Disease Type I; Humans; Hypoglycemia; Leucine; Liver Glycogen; Liver Neoplasms; Mesenchymoma; Neoplasms; Retroperitoneal Neoplasms; Thoracic Neoplasms; Tolbutamide | 1964 |
[Biosynthesis of catalase in liver (author's transl)].
Topics: Animals; Carbon Radioisotopes; Catalase; In Vitro Techniques; Iron; Iron Radioisotopes; Leucine; Levulinic Acids; Liver; Liver Neoplasms; Polyribosomes; Rats; RNA, Messenger; Tritium | 1973 |
Further chapters in the hydrazine story.
Topics: Adenocarcinoma; Anemia, Hemolytic; Animals; Carbon Isotopes; Carcinogens; Colonic Neoplasms; Cricetinae; DNA; Female; Humans; Hydrazines; Intestinal Mucosa; Leucine; Liver; Liver Neoplasms; Male; Mice; Occupational Medicine; Rats; RNA; Sulfates; Sulfur Isotopes; Urethane | 1971 |
168 other study(ies) available for leucine and Liver Neoplasms
Article | Year |
---|---|
Design, synthesis and biological evaluation of hybrid of ubenimex-fluorouracil for hepatocellular carcinoma therapy.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Leucine; Liver Neoplasms; Molecular Structure; Structure-Activity Relationship | 2021 |
Tripartite motif-containing protein 11 promotes hepatocellular carcinogenesis through ubiquitin-proteasome-mediated degradation of pleckstrin homology domain leucine-rich repeats protein phosphatase 1.
Topics: Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Leucine; Liver Neoplasms; Pleckstrin Homology Domains; Proteasome Endopeptidase Complex; Protein Phosphatase 1; Proto-Oncogene Proteins c-akt; Tripartite Motif Proteins; Ubiquitin; Ubiquitin-Protein Ligases | 2022 |
DeepHisCoM: deep learning pathway analysis using hierarchical structural component models.
Topics: Biological Factors; Carcinoma, Hepatocellular; COVID-19; Deep Learning; Gonadotropin-Releasing Hormone; Humans; Isoleucine; Leucine; Liver Neoplasms; Lysine; Mitogen-Activated Protein Kinases; Phenylalanine; Tryptophan; Tyrosine; Valine | 2022 |
[Cell metabolomics study of ginkgo flavone aglycone combined with doxorubicin against liver cancer in synergy].
Topics: Arginine; beta-Alanine; Doxorubicin; Flavones; Ginkgo biloba; Glutathione; Humans; Isoleucine; Leucine; Liver Neoplasms; Metabolomics; Phenylalanine; Proline; Tandem Mass Spectrometry; Tyrosine; Valine | 2022 |
Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis.
Topics: Amino Acids, Essential; Carcinoma, Hepatocellular; Humans; Leucine; Liver Neoplasms; Tryptophan; Valine | 2022 |
Safety of Patients with Hepatitis C Virus Treated with Glecaprevir/Pibrentasvir from Clinical Trials and Real-World Cohorts.
Topics: Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Carcinoma, Hepatocellular; Cyclopropanes; Genotype; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Leucine; Liver Neoplasms; Proline; Pyrrolidines; Quinoxalines; Sulfonamides | 2021 |
BC-02 eradicates liver cancer stem cells by upregulating the ROS-dependent DNA damage.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; DNA Damage; Female; Fluorouracil; Humans; Leucine; Liver Neoplasms; Mice; Mice, Nude; Neoplastic Stem Cells; Reactive Oxygen Species; Up-Regulation; Xenograft Model Antitumor Assays | 2017 |
DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma.
Topics: Animals; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Gene Knockout Techniques; GTPase-Activating Proteins; Humans; Leucine; Liver Neoplasms; Male; Mice; Oxidative Stress; Reactive Oxygen Species; Repressor Proteins; RNA-Binding Proteins; Signal Transduction; Starvation; Tumor Suppressor Proteins | 2018 |
Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry.
Topics: Animals; Antineoplastic Agents; Binding Sites; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Molecular Docking Simulation; Neovascularization, Physiologic; Protease Inhibitors; Protein Structure, Tertiary; Structure-Activity Relationship | 2018 |
Application of capillary electrophoresis coupling with electrochemiluminescence detection to estimate activity of leucine aminopeptidas.
Topics: Case-Control Studies; Cholestasis; Electrophoresis, Capillary; Enzyme Stability; Female; Hepatitis; Humans; Hydrogen-Ion Concentration; Leucine; Leucyl Aminopeptidase; Limit of Detection; Liver Neoplasms; Luminescent Measurements; Male; Proline; Reproducibility of Results; Signal-To-Noise Ratio | 2013 |
A multifunctional drug combination shows highly potent therapeutic efficacy against human cancer xenografts in athymic mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Proliferation; Dexamethasone; Dipyridamole; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured; Tumor Microenvironment; Vasodilator Agents; Xenograft Model Antitumor Assays | 2014 |
Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation.
Topics: Animals; Antineoplastic Agents; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship | 2016 |
Aminopeptidase N inhibitor 4cc synergizes antitumor effects of 5-fluorouracil on human liver cancer cells through ROS-dependent CD13 inhibition.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; CD13 Antigens; Cell Line, Tumor; Drug Synergism; Female; Fluorouracil; Humans; Hydroxamic Acids; Leucine; Liver Neoplasms; Membrane Potential, Mitochondrial; Mice; Mitochondria; Reactive Oxygen Species; Urea; Xenograft Model Antitumor Assays | 2015 |
A CD13 inhibitor, ubenimex, synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; CD13 Antigens; Cell Cycle; Cell Line, Tumor; Cisplatin; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Leucine; Liver Neoplasms; Neoplastic Stem Cells; Niacinamide; Phenylurea Compounds; Reactive Oxygen Species; Sorafenib | 2016 |
Hypoxia and leucine deprivation induce human insulin-like growth factor binding protein-1 hyperphosphorylation and increase its biological activity.
Topics: Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Genetic Variation; Humans; Insulin-Like Growth Factor Binding Protein 1; Kinetics; Leucine; Liver Neoplasms; Mass Spectrometry; Phosphopeptides; Phosphorylation | 2009 |
Differential efficacy of protease inhibitors against HCV genotypes 2a, 3a, 5a, and 6a NS3/4A protease recombinant viruses.
Topics: Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Cyclopropanes; Genotype; Hepacivirus; Hepatitis C; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Isoindoles; Lactams; Lactams, Macrocyclic; Leucine; Liver Neoplasms; Molecular Sequence Data; Oligopeptides; Proline; Protease Inhibitors; Sulfonamides; Treatment Outcome; Viral Nonstructural Proteins | 2011 |
Amino acid substitutions in the hepatitis C virus core region are associated with postoperative recurrence and survival of patients with HCV genotype 1b-associated hepatocellular carcinoma.
Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Biomarkers, Tumor; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatectomy; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Leucine; Liver; Liver Function Tests; Liver Neoplasms; Male; Methionine; Middle Aged; Neoplasm Recurrence, Local; Polymerase Chain Reaction; Prognosis; RNA, Messenger; Survival Analysis; Viral Core Proteins | 2011 |
M6P/IGF2R modulates the invasiveness of liver cells via its capacity to bind mannose 6-phosphate residues.
Topics: Animals; Cell Line; Cell Movement; Cell Proliferation; Hepatocytes; Humans; Leucine; Liver Neoplasms; Lysosomes; Mannosephosphates; Mice; Neoplasm Invasiveness; Protein Binding; Rats; Receptor, IGF Type 2 | 2012 |
A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Biological Transport; Carcinoma, Hepatocellular; Cell Fractionation; Cell Nucleus; Conserved Sequence; COS Cells; DNA; DNA-Binding Proteins; Epidermal Growth Factor; Fluorescent Antibody Technique; Gene Deletion; Gene Expression; Humans; Immunosorbent Techniques; Leucine; Liver Neoplasms; Mice; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Phosphorylation; Polymerase Chain Reaction; Protein Structure, Secondary; Signal Transduction; STAT3 Transcription Factor; Structure-Activity Relationship; Trans-Activators; Transfection; Tumor Cells, Cultured; Tyrosine | 2003 |
SERUM LACTIC DEHYDROGENASE, LEUCINE AMINOPEPTIDASE AND 5-NUCLEOTIDASE ACTIVITIES: OBSERVATION IN PATIENTS WITH CARCINOMA OF THE PANCREAS AND HEPATOBILIARY DISEASE.
Topics: Aminopeptidases; Blood Chemical Analysis; Carcinoma; Carcinoma, Hepatocellular; Cholelithiasis; Clinical Enzyme Tests; Hepatitis; Hepatitis A; Humans; Jaundice; Jaundice, Obstructive; L-Lactate Dehydrogenase; Leucine; Leucyl Aminopeptidase; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Liver Neoplasms; Nucleotidases; Pancreas; Pancreatic Neoplasms; Pancreatitis | 1963 |
ELEVATED SERUM LEUCINE AMINOPEPTIDASE ACTIVITY: CLINICAL SIGNIFICANCE IN PANCREATIC CARCINOMA.
Topics: Aminopeptidases; Clinical Enzyme Tests; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms | 1963 |
EFFECTS OF CARCINOGENIC AMINES ON AMINO ACID INCORPORATION BY LIVER SYSTEMS. II. A MORPHOLOGICAL AND BIOCHEMICAL STUDY ON THE EFFECT OF DIMETHYLNITROSAMINE.
Topics: Amines; Amino Acids; Carbon Isotopes; Carcinogens; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Electrons; Hepatitis; Leucine; Liver; Liver Glycogen; Liver Neoplasms; Microscopy; Microscopy, Electron; Mitochondria; Nitrosamines; Proteins; Rats; Research; Toxicology | 1963 |
PEPITASE ACTIVITIES IN TISSUES OF TUMOR-BEARING RATS.
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Erythrocytes; Glycine; Leucine; Liver; Liver Neoplasms; Muscles; Neoplasms; Neoplasms, Experimental; Peptide Hydrolases; Peptides; Proline; Rats; Research; Sarcoma; Sarcoma, Experimental | 1963 |
LEUCINE AMINOPEPTIDASE ACTIVITY IN CEREBROSPINAL FLUID.
Topics: Aminopeptidases; Brain Diseases; Brain Neoplasms; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Clinical Enzyme Tests; Humans; Leucine; Leucyl Aminopeptidase; Liver Cirrhosis; Liver Neoplasms; Research; Spinal Cord Neoplasms | 1963 |
[THE CHANGES IN PROTEIN-RIBONUCLEIC ACID METABOLISM IN LIVER EPITHELIAL CELLS DURING EXPERIMENTAL CANCERIZATION WITH DIETHYLNITROSAMINE].
Topics: Autoradiography; Carcinogens; Cell Nucleus; Diethylnitrosamine; DNA; DNA, Neoplasm; Epithelial Cells; Leucine; Liver Neoplasms; Metabolism; Neoplasm Proteins; Nitrosamines; Proteins; Rats; Research; RNA; RNA, Neoplasm; Tritium | 1963 |
[ACTION OF METABOLIC INHIBITORS ON ENERGY METABOLISM AND ON PROTEIN SYNTHESIS OF TUMOR AND EMBRYONAL CELLS].
Topics: Adenosine Triphosphate; Amino Acids; Antimetabolites; Carcinoma, Hepatocellular; Cell Biology; Chick Embryo; Dinitrophenols; Embryo, Mammalian; Embryo, Nonmammalian; Energy Metabolism; Glycine; Hexoses; Leucine; Liver Neoplasms; Manometry; Metabolism; Neoplasms; Neoplasms, Experimental; Pharmacology; Protein Biosynthesis; Proteins; Rats; Research | 1963 |
THE DIAGNOSTIC VALUE OF SERUM LEUCINE AMINOPEPTIDASE.
Topics: Adolescent; Aminopeptidases; Chemical and Drug Induced Liver Injury; Child; Cholecystitis; Cholelithiasis; Clinical Enzyme Tests; Gallstones; Geriatrics; Hepatitis; Hepatitis A; Jaundice; Jaundice, Obstructive; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms | 1964 |
[LEUCINAMINOPEPTIDASE ACTIVITY OF THE BLOOD OF PATIENTS WITH VARIOUS TYPES OF LIVER DISEASES].
Topics: Aminopeptidases; Cholangitis; Cholecystitis; Cholelithiasis; Clinical Enzyme Tests; Hepatitis; Jaundice; Jaundice, Obstructive; Leucine; Liver Cirrhosis; Liver Diseases; Liver Neoplasms | 1963 |
[SOME ASPECTS OF THE REGULATION OF RIBONUCLEIC ACID BIOSYNTHESES IN HIGHER ANIMALS].
Topics: Carcinoma, Hepatocellular; Chromatography; Leucine; Liver; Liver Neoplasms; Metabolism; NAD; Neoplasms, Experimental; Niacinamide; Nucleoproteins; Nucleotidases; Phosphorus Isotopes; Proteins; Rats; Research; RNA; RNA, Messenger; Vitamin E Deficiency | 1964 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
CLINICAL AND BIOCHEMICAL STUDIES IN PATIENTS WITH FUNCTIONING ISLET CELL TUMORS.
Topics: Adenoma, Islet Cell; Amino Acids; Biochemical Phenomena; Biochemistry; Biomedical Research; Carbohydrate Metabolism; Glucose; Glucose Tolerance Test; Glutarates; Humans; Hypoglycemia; Insulin; Isoleucine; Leucine; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Research; Valine | 1964 |
INHIBITION OF AMINO ACID INCORPORATION INTO PROTEIN OF YOSHIDA ASCITES HEPATOMA CELLS BY GLYCERALDEHYDE.
Topics: Amino Acids; Ascites; Carbon Isotopes; Carcinoma, Hepatocellular; Glyceraldehyde; Leucine; Liver Neoplasms; Neoplasm Proteins; Pharmacology; Proteins; Radiometry; Rats; Research; Sarcoma; Sarcoma, Yoshida | 1964 |
RIBONUCLEOTIDE AND AMINO ACID TRANSFER FROM SOLUBLE RNA TO MICROSOMES FROM NORMAL AND NEOPLASTIC TISSUE.
Topics: Acetates; Adenosine Triphosphate; Amino Acids; Animals; Bile Acids and Salts; Carbon Isotopes; Carcinoma, Hepatocellular; Guanine Nucleotides; Leucine; Liver; Liver Neoplasms; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Metabolism; Microsomes; Neoplasms, Experimental; Pharmacology; Phosphorus Isotopes; Polynucleotides; Pyruvates; Rats; Research; Ribosomes; RNA; RNA, Neoplasm; Salts | 1964 |
THE EVALUATION OF SERUM LEUCINE-AMINOPEPTIDASE ESTIMATION; THE INFLUENCE OF THE ADMINISTRATION OF STEROIDS ON S-LAP ACTIVITY IN OBSTRUCTIVE DISEASES OF THE BILIARY TRACT. (PRELIMINARY REPORT).
Topics: Alkaline Phosphatase; Biliary Tract; Cholelithiasis; Clinical Enzyme Tests; Drug Therapy; Gallbladder Neoplasms; Humans; Leucine; Leucyl Aminopeptidase; Liver Diseases; Liver Neoplasms; Pancreatic Neoplasms; Prednisone; Surgical Procedures, Operative | 1964 |
EVIDENCE FAVORING THE SARCOMATOUS ORIGIN OF AN INSULIN-LIKE SUBSTANCE IN A CASE OF FIBROSARCOMA WITH HYPOGLYCEMIA.
Topics: Blood Glucose; Calcium Isotopes; Chemical Phenomena; Chemistry; Epinephrine; Fibrosarcoma; Glucagon; Glucose Tolerance Test; Growth Hormone; Human Growth Hormone; Humans; Hypoglycemia; Insulin; Leucine; Liver Neoplasms; Pathology; Prolactin; Radioisotopes; Radionuclide Imaging; Tolbutamide | 1965 |
The intra-cellular distribution of cathepsin, benzoylarginine amidase and leucine amidase activities in normal rat tissues and primary rat hepatoma.
Topics: Amidohydrolases; Animals; Carcinoma, Hepatocellular; Cathepsins; Leucine; Liver Neoplasms; Liver Neoplasms, Experimental; Rats | 1951 |
Region 752-761 of STAT3 is critical for SRC-1 recruitment and Ser727 phosphorylation.
Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Conserved Sequence; DNA-Binding Proteins; E1A-Associated p300 Protein; Gene Expression; Histone Acetyltransferases; Humans; Interleukin-6; Leucine; Liver Neoplasms; Mice; Nuclear Proteins; Nuclear Receptor Coactivator 1; Phenylalanine; Phosphorylation; Promoter Regions, Genetic; Protein Structure, Tertiary; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Serine; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Transcription, Genetic | 2004 |
Structural aspects of the B*3564 molecule, a novel HLA-B*35 allele identified by sequence-based typing.
Topics: Alleles; Base Pairing; Base Sequence; Carcinoma, Hepatocellular; Codon; Exons; Genetic Variation; Histocompatibility Testing; HLA-B Antigens; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Leucine; Liver Neoplasms; Models, Molecular; Sequence Analysis, DNA; Tyrosine | 2006 |
Inhibitory effect of alpha-fetoprotein on protein synthesis in a reticulocyte lysate cell-free system.
Topics: alpha-Fetoproteins; Carcinoma, Hepatocellular; Cell-Free System; Dose-Response Relationship, Drug; Fetal Blood; Humans; Leucine; Liver Neoplasms; Peptide Initiation Factors; Protein Biosynthesis; Reticulocytes; Serum Albumin | 1982 |
Amino acid incorporation into liver and tumor proteins in patients with hepatic neoplasms-effects of liver dearterialization.
Topics: Adult; Aged; Amino Acids; Female; Hepatic Artery; Humans; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Middle Aged; Neoplasm Proteins; Proteins | 1980 |
Modulators of protein kinase C inhibit hypoxia-induced erythropoietin production.
Topics: Blotting, Northern; Calcimycin; Carcinoma, Hepatocellular; Diglycerides; DNA; Dose-Response Relationship, Drug; Erythropoietin; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Leucine; Liver Neoplasms; Protein Kinase C; Radioimmunoassay; RNA; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured; Uridine | 1993 |
Apolipoprotein A-I synthesis and secretion are increased in Hep G2 cells depleted of copper by cupruretic tetramine.
Topics: Apolipoprotein A-I; Apolipoproteins B; Chelating Agents; Copper; Hepatoblastoma; Humans; Leucine; Liver Neoplasms; Polyamines; Precipitin Tests; Tritium; Tumor Cells, Cultured | 1995 |
Lymphocyte protein synthesis in vivo: a measure of activation.
Topics: Adult; Carbon Isotopes; Colorectal Neoplasms; Humans; Immunophenotyping; Interleukin-2; Leucine; Liver Neoplasms; Lymphocyte Activation; Lymphocytes; Male; Protein Biosynthesis; Recombinant Proteins; Thymidine | 1994 |
Adaptive regulation of amino acid transport in nutrient-deprived human hepatomas.
Topics: Adaptation, Physiological; Alanine; Amino Acids; Arginine; Biological Transport; Carcinoma, Hepatocellular; Cell Division; Cell Line; Glutamine; Humans; Leucine; Liver Neoplasms; Tumor Cells, Cultured | 1996 |
Low rates of apoB secretion from HepG2 cells result from reduced delivery of newly synthesized triglyceride to a "secretion-coupled" pool.
Topics: Apolipoproteins B; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Division; Cell Line; Glycerol; Humans; Kinetics; Leucine; Liver Neoplasms; Oleic Acid; Triglycerides; Tritium; Tumor Cells, Cultured | 1996 |
Common conformational effects in the p53 protein of vinyl chloride-induced mutations.
Topics: Animals; Carcinogens; Crystallography, X-Ray; Genes, p53; Hemangiosarcoma; Humans; Immunoenzyme Techniques; Leucine; Liver Neoplasms; Mice; Models, Molecular; Mutagenesis; Protein Conformation; Tumor Suppressor Protein p53; Vinyl Chloride | 1999 |
Amino acid uptake and regulation in multicellular hepatoma spheroids.
Topics: Amino Acid Transport System ASC; Amino Acids; Arginine; beta-Alanine; Biological Transport; Blotting, Northern; Carcinogens; Carcinoma, Hepatocellular; Carrier Proteins; Cell Culture Techniques; Cell Division; Gene Expression; Glutamine; Humans; Leucine; Liver Neoplasms; Microscopy, Electron, Scanning; Minor Histocompatibility Antigens; Protein Kinase C; Receptors, Virus; RNA, Messenger; Sodium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Effects of platelet-activating factor, tumor necrosis factor, and interleukin-1alpha on the expression of apolipoprotein M in HepG2 cells.
Topics: Apolipoprotein A-I; Apolipoproteins; Apolipoproteins B; Apolipoproteins E; Apolipoproteins M; Dose-Response Relationship, Drug; Gene Expression; Hepatoblastoma; Humans; Imidazoles; Interleukin-1; Leucine; Lipocalins; Liver Neoplasms; Platelet Activating Factor; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
A new method for peptidase activity measurement in serum and tissues, using L-Leu-L-Leu as substrate.
Topics: Adult; Aged; Alanine Transaminase; Amino Acid Oxidoreductases; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Carcinoma, Hepatocellular; Child; Clinical Enzyme Tests; Dipeptides; Female; Hepatitis; Humans; Hydrogen-Ion Concentration; Leucine; Liver Neoplasms; Male; Middle Aged; Peptide Hydrolases; Rats | 1977 |
Biochemical effects of bleomycin A2 on Novikoff hepatoma ascites cells.
Topics: Ascitic Fluid; Bleomycin; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; DNA, Neoplasm; Leucine; Liver Neoplasms; Neoplasms, Experimental; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Phosphorus; Phosphorus Radioisotopes; RNA, Neoplasm; RNA, Ribosomal; Thymidine; Transcription, Genetic; Tritium; Uridine | 1975 |
Synthesis of alpha-fetoprotein by rat ascites hepatoma cells.
Topics: alpha-Fetoproteins; Animals; Bucladesine; Carcinoma, Hepatocellular; Fetal Proteins; Kinetics; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Polyribosomes; Protein Biosynthesis; Rats; Ribosomes; Theophylline | 1975 |
Isozyme patterns of branched-chain amino acid transaminase during cellular differentiation and carcinogenesis.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Cell Differentiation; Cell Transformation, Neoplastic; Female; Isoenzymes; Isoleucine; Kinetics; Leucine; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; Organ Specificity; Rats; Transaminases; Valine | 1975 |
Carcinoembryonic proteins in gastric carcinoma metastatic to the liver.
Topics: Adult; Alkaline Phosphatase; alpha-Fetoproteins; Carcinoembryonic Antigen; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Female; Hot Temperature; Humans; Leucine; Liver Neoplasms; Male; Phenylalanine; Placenta; Pregnancy; Stomach Neoplasms | 1979 |
Effect of a normal serum protein absent from hepatoma-bearing animals on cell cultures.
Topics: Animals; Blood Proteins; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Contact Inhibition; Electrophoresis, Polyacrylamide Gel; Growth Substances; L Cells; Leucine; Liver Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Inbred BUF; Thymidine | 1975 |
Complement biosynthesis in vitro by rat hepatoma cell strains.
Topics: Animals; Autoradiography; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, Gel; Complement Inactivator Proteins; Complement System Proteins; Cycloheximide; Erythrocytes; Humans; Hydrocortisone; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Isoleucine; Leucine; Liver Neoplasms; Lysine; Male; Rabbits; Rats; Sheep; Valine | 1975 |
Effects of cyclic adenosine monophosphate, dexamethasone and insulin on phosphoenolpyruvate carboxykinase synthesis in Reuber H-35 hepatoma cells.
Topics: Animals; Bucladesine; Carcinoma, Hepatocellular; Cells, Cultured; Dactinomycin; Deoxyadenosines; Dexamethasone; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Glucagon; Glucose; Insulin; Kinetics; Leucine; Liver Neoplasms; Neoplasms, Experimental; Phosphoenolpyruvate Carboxykinase (GTP); Rats; RNA; RNA, Messenger; Theophylline | 1975 |
Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells.
Topics: Amino Acids; Arginine; Canavanine; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Fetal Blood; Insulin; Leucine; Leupeptins; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Pepstatins; Phenylmethylsulfonyl Fluoride; Phosphoenolpyruvate Carboxykinase (GTP); Puromycin | 1976 |
Stimulation of the biosynthesis of membrane glycoproteins from Zajdela ascites hepatoma cells by Robinia lectin.
Topics: Animals; Carcinoma, Hepatocellular; Cell Membrane; Glucosamine; Glycoproteins; Kinetics; Lectins; Leucine; Liver Neoplasms; Molecular Weight; Neoplasms, Experimental; Trypsin | 1976 |
Studies on the turnover rates of ornithine aminotransferase in Morris hepatoma 44 and host liver.
Topics: Animals; Carcinoma, Hepatocellular; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Ornithine-Oxo-Acid Transaminase; Rats; Transaminases | 1976 |
Albumin synthesis in cultured hempatoma cells. Regulation by essential amino acids.
Topics: Albumins; Amino Acids; Carcinoma, Hepatocellular; Cell Line; Histidine; Isoleucine; Kinetics; Leucine; Liver Neoplasms; Neoplasms, Experimental; Phenylalanine; Protein Biosynthesis; Tryptophan | 1977 |
Antiproliferative activity of anti-inflammatory drugs in two mammalian cell culture lines.
Topics: Animals; Anti-Inflammatory Agents; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cyclooxygenase Inhibitors; DNA; Dose-Response Relationship, Drug; Fibroblasts; In Vitro Techniques; Leucine; Liver Neoplasms; Protein Biosynthesis; Rats; RNA; Thymidine; Time Factors; Uridine | 1977 |
Isozyme patterns of branched-chain amino acid transaminase in human tissues and tumors.
Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Female; Fetus; Humans; In Vitro Techniques; Isoenzymes; Isoleucine; Kidney Neoplasms; Leucine; Liver Neoplasms; Male; Neoplasms; Rats; Species Specificity; Stomach Neoplasms; Substrate Specificity; Tissue Distribution; Transaminases; Valine | 1977 |
Effect of sodium octanoate on leucine incorporation into protein of rat liver slices and of Yoshida ascites hepatoma cells.
Topics: Animals; Caprylates; Carcinoma, Hepatocellular; Cell Line; Depression, Chemical; Female; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Protein Biosynthesis; Rats | 1978 |
Kinetics of steroid induction and deinduction of tyrosine aminotransferase synthesis in cultured hepatoma cells.
Topics: Animals; Blood; Carcinoma, Hepatocellular; Cattle; Cells, Cultured; Computers; Dexamethasone; Enzyme Induction; Insulin; Kinetics; Leucine; Liver Neoplasms; Models, Chemical; Precipitin Tests; Rats; RNA, Messenger; Tyrosine Transaminase | 1975 |
A comparison of canine normal hepatic alkaline phosphatase and variant alkaline phosphatase of serum and liver.
Topics: Adrenal Cortex Diseases; Adrenal Cortex Hormones; Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Dogs; Drug Stability; Enzyme Induction; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Leucine; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Neoplasm Metastasis; Phenylalanine; Time Factors | 1975 |
Formation, size, and solubility in chloroform/methanol of products of protein synthesis in isolated mitochondria of rat liver and Zajdela hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Chloramphenicol; Chloroform; Female; Hydrogen-Ion Concentration; Isoleucine; Leucine; Liver Neoplasms; Liver Regeneration; Male; Membranes; Methanol; Mitochondria, Liver; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Phenylalanine; Protein Biosynthesis; Rats; Solubility; Time Factors | 1975 |
Effects of extracellular Ca2+ and Mg2+ on nucleic acids and proteins syntheses by tumor and normal liver cells.
Topics: Animals; Calcium; Cell Membrane Permeability; DNA; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Magnesium; Protein Biosynthesis; Rats; RNA; Thymidine; Uridine | 1978 |
Specific killing of line-10 cells in vitro in the presence of normal lymphoid cells and antibodies from immune rabbits or tumor-resistant guinea pigs.
Topics: Animals; Antibodies; Antibody Specificity; Antibody-Dependent Cell Cytotoxicity; Binding Sites, Antibody; Cell Line; Guinea Pigs; Immune Sera; Immunity; Immunoglobulin Fc Fragments; Leucine; Liver Neoplasms; Lymphocytes; Rabbits; Thymidine | 1978 |
Effects of nine N-nitroso compounds on the specific radioactivity of liver proteins after injection of [14C]leucine into rats.
Topics: Animals; Cycloleucine; Diethylnitrosamine; Dimethylnitrosamine; Leucine; Liver; Liver Neoplasms; Male; Methylnitrosourea; Morpholines; Necrosis; Nitroso Compounds; Piperazines; Piperidines; Proteins; Rats; Sarcosine; Time Factors | 1977 |
Aminopeptidases and arylamidases in normal and cancer tissues in humans.
Topics: Alanine; Amides; Aminopeptidases; Colon; Digestive System; Humans; Ileum; Kidney; Leucine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Methionine; Naphthalenes; Neoplasms; Phenylalanine; Rectum; Stomach; Stomach Neoplasms | 1975 |
A comparison of the ability of normal liver, a premalignant liver, a solid hepatoma and the Zajdela ascitic hepatoma, to take up amino acids in vitro.
Topics: Amino Acids; Animals; Arginine; In Vitro Techniques; Kinetics; Leucine; Liver; Liver Neoplasms; Lysine; Methionine; Phenylalanine; Precancerous Conditions; Valine | 1976 |
Expression of 27-kD heat-shock protein isoforms in human neoplastic and nonneoplastic liver tissues.
Topics: Adolescent; Adult; Aged; Female; Heat-Shock Proteins; Humans; Infant; Leucine; Liver; Liver Neoplasms; Male; Middle Aged | 1992 |
The effect of anti-alpha-fetoprotein-adriamycin conjugate on a human hepatoma.
Topics: alpha-Fetoproteins; Animals; Antibodies, Monoclonal; Carcinoma, Hepatocellular; Cross-Linking Reagents; Dextrans; Doxorubicin; Humans; Immunotoxins; Leucine; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Polyglutamic Acid; Thymidine; Tumor Cells, Cultured | 1990 |
Contribution of elevated protein turnover and anorexia to cachexia in patients with hepatocellular carcinoma.
Topics: Adolescent; Adult; Aged; Amino Acids; Anorexia; Blood Proteins; Cachexia; Carcinoma, Hepatocellular; Feeding and Eating Disorders; Female; Humans; Leucine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Oxidation-Reduction; Protein Biosynthesis; Proteins | 1990 |
Sulfation of tyrosine residues in coagulation factor V.
Topics: Amino Acid Sequence; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Factor V; Factor VIII; Humans; Leucine; Liver Neoplasms; Molecular Sequence Data; Molecular Weight; Sulfates; Thrombin; Tritium; Tyrosine | 1990 |
Synthesis of transcobalamin II by cultured human hepatocytes.
Topics: Apoproteins; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Humans; Immunologic Techniques; Leucine; Liver Neoplasms; Transcobalamins | 1985 |
[Biosynthesis of proteins characteristic of the regeneration of liver and hepatoma].
Topics: Alpha-Globulins; Animals; Beta-Globulins; Blood Proteins; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Dactinomycin; gamma-Globulins; Hepatectomy; Injections, Intraperitoneal; Injections, Subcutaneous; Leucine; Liver Neoplasms; Liver Regeneration; Male; Neoplasm Transplantation; Rats | 1972 |
Characterization of polyribosomes and maturation of ribosomal RNA in hepatoma cells treated with 5-azacytidine.
Topics: Animals; Azacitidine; Carcinoma, Hepatocellular; Cell Fractionation; Cells, Cultured; Cytoplasm; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Polyribosomes; Rats; RNA, Ribosomal; Time Factors; Tritium | 1974 |
Post-transcriptional inhibition of protein synthesis by rifampicin in rat hepatoma cells.
Topics: Ammonium Sulfate; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; DNA-Directed RNA Polymerases; Enzyme Activation; Enzyme Induction; Hydrocortisone; Leucine; Liver Neoplasms; Magnesium; Manganese; Neoplasm Proteins; Protein Biosynthesis; Rats; Rifampin; RNA, Neoplasm; Transcription, Genetic; Tyrosine Transaminase; Uracil | 1973 |
Further evidence against post-transcriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells.
Topics: Adenosine; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Dactinomycin; Deoxyadenosines; Enzyme Induction; Enzyme Repression; Hydrocortisone; Kinetics; Leucine; Liver Neoplasms; RNA, Messenger; RNA, Ribosomal; Transcription, Genetic; Tritium; Tyrosine Transaminase | 1973 |
Hormonal mechanisms in regulation of gene expression.
Topics: Animals; Antigen-Antibody Reactions; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Enzyme Induction; Genes; Hydrocortisone; Immunodiffusion; Insulin; Isotope Labeling; Kinetics; Leucine; Liver; Liver Neoplasms; Rats; RNA, Messenger; Time Factors; Tyrosine Transaminase | 1973 |
Hormonal regulation of protein degradation in hepatoma cells in tissue culture.
Topics: Animals; Blood; Carcinoma, Hepatocellular; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; In Vitro Techniques; Insulin; Leucine; Liver Neoplasms; Proteins; Rats; Tritium; Tyrosine Transaminase | 1974 |
Activity of some hydrolases in animals with transplanted and spontaneous tumours.
Topics: Aminopeptidases; Animals; Carcinoma, Hepatocellular; Cricetinae; Female; gamma-Glutamyltransferase; Glycine; Hydrolases; Leucine; Liver; Liver Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Organ Specificity; Pyrrolidines; Rats; Rats, Inbred Strains; Sarcoma; Sarcoma, Yoshida; Species Specificity; Time Factors | 1973 |
Inhibition of messenger RNA accumulation but not translation in ultraviolet irradiated hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Dactinomycin; DNA, Neoplasm; Dose-Response Relationship, Radiation; Enzyme Induction; Hydrocortisone; Insulin; Leucine; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Radiation Effects; Rats; RNA, Messenger; RNA, Neoplasm; Spectrophotometry, Ultraviolet; Thymidine; Time Factors; Transcription, Genetic; Tritium; Tyrosine Transaminase; Ultraviolet Rays; Uridine | 1974 |
A comparison of enzyme-active membrane antigens from two different 4-dimethylaminoazobenzene-induced rat hepatomas with those of adult and fetal rat liver.
Topics: Acid Phosphatase; Aminopeptidases; Animals; Antigens; Carcinoma, Hepatocellular; Cell Membrane; Esterases; Fetus; Glutamates; Leucine; Liver; Liver Neoplasms; Microsomes, Liver; NADH, NADPH Oxidoreductases; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Phosphoric Monoester Hydrolases; Rats; Tetrazoles | 1974 |
Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase and tyrosine aminotransferase in hepatoma cells in culture.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Deoxyadenosines; Dexamethasone; Drug Synergism; Enzyme Induction; Leucine; Liver Neoplasms; Microsomes; Mixed Function Oxygenases; Neoplasm Proteins; Protein Biosynthesis; Rats; RNA, Neoplasm; Spectrophotometry; Transcription, Genetic; Tritium; Tyrosine Transaminase; Uridine | 1974 |
Synthesis of ferritin in cultured hepatoma cells.
Topics: Animals; Antigen-Antibody Reactions; Carcinoma, Hepatocellular; Cell Line; Cell-Free System; Dexamethasone; Enzyme Induction; Ferritins; Leucine; Liver Neoplasms; Neoplasm Proteins; Protein Biosynthesis; Rabbits; Spectrophotometry, Ultraviolet; Tritium; Tyrosine Transaminase | 1974 |
Polyribosomes in rat tissues. IV. On the abnormal dimer peak in hepatomas.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Carcinoma, Hepatocellular; Dactinomycin; In Vitro Techniques; Leucine; Liver Neoplasms; Neoplasms, Experimental; Rats; Ribosomes; RNA, Messenger; Temperature; Ultracentrifugation | 1966 |
Lack of secretion of serum protein by transplanted rat hepatomas.
Topics: Animals; Blood Protein Electrophoresis; Blood Proteins; Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Histidine; Leucine; Liver; Liver Neoplasms; Lysine; Neoplasm Proteins; Neoplasms, Experimental; Rats | 1966 |
Studies on nucleolar 4 to 6 S ribonucleic acid of Novikoff hepatoma cells.
Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Chromatography, Gel; Cytosine Nucleotides; Electrophoresis, Disc; Leucine; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphates; Phosphorus Isotopes; Rats; Ribosomes; RNA; Templates, Genetic; Uracil Nucleotides | 1968 |
[Old and new on butter yellow].
Topics: Animals; Carcinoma; Carcinoma, Hepatocellular; DNA; Glucose-6-Phosphatase; Leucine; Liver; Liver Neoplasms; Microsomes; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Proteins; Rats; RNA; Tritium | 1967 |
A possible role of transfer RNA in the mechanism of carcinogenesis.
Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Ethionine; Genetic Code; Leucine; Liver Neoplasms; Neoplasms, Experimental; RNA, Transfer; Tritium | 1968 |
Profiles of total ribonucleoprotein particles from normal rat liver, primary liver tumors, and Novikoff hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Histocytochemistry; Leucine; Liver; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Nucleoproteins; Rats; Ribonucleases; Ribosomes; RNA; RNA, Neoplasm; Sucrose | 1969 |
The effect of esteroproteases from mouse submaxillary gland on the growth of rat hepatoma cells in tissue culture.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Division; Culture Techniques; DNA; Esterases; Leucine; Liver Neoplasms; Mice; Neoplasms, Experimental; Peptide Hydrolases; Submandibular Gland; Thymidine | 1969 |
Studies of control of tissue protein levels: differential responses of tumor and liver to fasting.
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA; Fasting; Leucine; Liver; Liver Neoplasms; Lysine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Proteins; Rats; Ribosomes; RNA | 1968 |
The proption of the incorporation of leucine into albumin to that into totaprotein in rat liver and hepatoma Morris 5123 TC.
Topics: Animals; Blood Proteins; Carbon Isotopes; Carcinoma, Hepatocellular; Electrophoresis; Immune Sera; Immunochemistry; Immunodiffusion; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Rabbits; Rats; Serum Albumin; Time Factors; Tritium | 1969 |
Ribosome formation in rat liver: evidence for post-transcriptional control.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites; Azaguanine; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Density Gradient; Cycloheximide; Cytoplasm; Depression, Chemical; Feedback; Leucine; Liver; Liver Neoplasms; Male; Metabolism; Neoplasms, Experimental; Orotic Acid; Puromycin; Pyrrolidines; Rats; Ribosomes; RNA; Stimulation, Chemical; Time Factors; Tryptophan | 1969 |
Stimulation of 14C-leucine incorporation into protein in vitro by rapidly sedimenting nucleolar RNA from AH-130 hepatoma cells.
Topics: Amino Acids; Animals; Bacterial Proteins; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Escherichia coli; Leucine; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Rats; RNA, Neoplasm; Stimulation, Chemical; Templates, Genetic | 1969 |
Adult and embryonic transfer RNA.
Topics: Animals; Biological Assay; Carbon Isotopes; Carcinoma, Hepatocellular; Cattle; Electrophoresis; Fetus; Leucine; Liver; Liver Neoplasms; Mice; RNA, Transfer; Tritium | 1970 |
Stimulation of amino acid incorporation into protein in vitro by various nuclear RNA fractions of the AH-130 hepatoma cells.
Topics: Amino Acids; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Density Gradient; In Vitro Techniques; Leucine; Liver Neoplasms; Neoplasm Proteins; Phenylalanine; RNA, Neoplasm | 1970 |
The ratio of albumin synthesis to total protein synthesis in normal rat liver, in host liver, and in Morris hepatoma 9121.
Topics: Albumins; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Paper; Electrophoresis; Injections, Intravenous; Leucine; Liver; Liver Neoplasms; Lysine; Neoplasm Proteins; Neoplasms, Experimental; Protein Binding; Protein Biosynthesis; Rats | 1970 |
The uptake of non-metabolizable amino acids as an index of cell viability in vitro.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Leucine; Liver; Liver Neoplasms; Rats; Trypan Blue | 1970 |
Effect of crystalline abrin on the biosynthesis of protein, RNA, and DNA in experimental tumors.
Topics: Animals; Antimetabolites; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA, Neoplasm; Hot Temperature; Leucine; Liver Neoplasms; Male; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Oxygen Consumption; Plant Proteins; Protein Denaturation; Rats; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1970 |
[Incorporation in vitro of DL-leucine-1-C14 into the proteins of the cells of Yoshida's ascites hepatoma and of ascitic sarcoma 180 in presence of various concentrations of albumin].
Topics: Albumins; Animals; Carcinoma, Hepatocellular; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; Sarcoma 180 | 1969 |
Transaminase of branched chain amino acids. VII. Comparative studies on isozymes of ascites hepatoma and various normal tissues of rat.
Topics: Adipose Tissue; Animals; Brain; Carcinoma, Hepatocellular; Chromatography; Chromatography, DEAE-Cellulose; Immunodiffusion; Isoenzymes; Isoleucine; Kidney; Leucine; Liver; Liver Neoplasms; Male; Molecular Weight; Muscles; Neoplasms, Experimental; Rats; Sarcoma, Yoshida; Spleen; Swine; Testis; Transaminases; Ultracentrifugation; Valine | 1970 |
[Clinical studies on serum leucyl glycyl glycine hydrolyzing enzyme in cancer. I].
Topics: Adult; Aged; Carcinoma, Hepatocellular; Cobalt; Edetic Acid; Electrophoresis; Female; Glycine; Hepatitis; Humans; Leucine; Liver Neoplasms; Male; Manganese; Middle Aged; Neoplasms; Peptide Hydrolases; Pregnancy | 1971 |
Cytochalasin B. I. Effect on cytokinesis of Novikoff hepatoma cells.
Topics: Animals; Antineoplastic Agents; Benzocycloheptenes; Carcinoma, Hepatocellular; Cell Division; Choline; Depression, Chemical; Dimethyl Sulfoxide; DNA, Neoplasm; In Vitro Techniques; Leucine; Liver Neoplasms; Mitosporic Fungi; Neoplasm Proteins; Neoplasms, Experimental; Rats; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1971 |
Some metabolic effects of halothane on mammalian tissue culture cells in vitro.
Topics: Acetates; Animals; Autoradiography; Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; DNA, Neoplasm; Fatty Acids; Halothane; Leucine; Liver Neoplasms; Neoplasms, Experimental; Phospholipids; Protein Biosynthesis; Rats; RNA, Neoplasm; Thymidine; Time Factors; Tritium; Uridine | 1971 |
The template activities of nuclear RNAs from rat liver, regenerating liver and hepatoma AH-130 cells.
Topics: Amino Acids; Animals; Base Sequence; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Density Gradient; Female; Hepatectomy; Leucine; Liver; Liver Neoplasms; Liver Regeneration; Male; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Rats; RNA; Templates, Genetic | 1971 |
Transfer RNA's of embryonic tissue.
Topics: Animals; Carcinoma, Hepatocellular; Cattle; Cell-Free System; Embryo, Mammalian; Female; Gestational Age; Leucine; Ligases; Liver; Liver Neoplasms; Methylation; Mice; Pregnancy; Proteins; Rabbits; RNA, Transfer; Tritium | 1971 |
Effect of tryptophan on polyribosomes and protein synthesis in liver.
Topics: Animals; Bile Acids and Salts; Carbon Isotopes; Carcinoma, Hepatocellular; Cell-Free System; Centrifugation, Density Gradient; Enteral Nutrition; Fasting; Female; Leucine; Liver; Liver Neoplasms; Membranes; Mice; Microsomes, Liver; Mitochondria, Liver; Neoplasm Transplantation; Protein Binding; Protein Biosynthesis; Rats; Ribosomes; Stimulation, Chemical; Surface-Active Agents; Tryptophan | 1971 |
[Kinetics of the incorporation of uridine ( 3 H) in subnucleolar fractions of rat ascites hepatoma cells].
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Female; Heparin; In Vitro Techniques; Kinetics; Leucine; Liver Neoplasms; Neoplasms, Experimental; Nucleoproteins; Rats; Ribosomes; RNA, Neoplasm; Tritium; Uridine | 1971 |
The metabolic effects of nonvolatile anesthetics on mammalian hepatoma cells in vitro. II. Inhibition of macromolecular precursor incorporation.
Topics: Amobarbital; Animals; Carcinoma, Hepatocellular; Culture Techniques; DNA, Neoplasm; Leucine; Lidocaine; Liver; Liver Neoplasms; Methohexital; Neoplasm Proteins; Neoplasms, Experimental; Rats; RNA, Neoplasm; Thiopental; Thymidine; Uridine | 1971 |
Turnover of the plasma-membrane and microsomal proteins of rat liver containing primary hepatoma nodules.
Topics: Animals; Carbon Isotopes; Carcinogens; Carcinoma, Hepatocellular; Cell Membrane; Centrifugation, Density Gradient; Fluorenes; Leucine; Liver Neoplasms; Male; Microsomes, Liver; Neoplasm Proteins; Neoplasms, Experimental; Nucleotidases; Rats | 1971 |
Effects of partial hepatectomy in rats on two transplantable hepatomas. Changes in weight and in synthesis of DNA and ferritin.
Topics: Animals; Autoradiography; Body Weight; Carcinoma, Hepatocellular; DNA, Neoplasm; Female; Ferritins; Hepatectomy; Leucine; Liver Neoplasms; Liver Regeneration; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thymidine; Time Factors; Tritium | 1971 |
Alterations in the transfer RNA population of hepatoma 9618A as compared with normal rat liver.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Leucine; Liver; Liver Neoplasms; Lysine; Male; Neoplasms, Experimental; Phenylalanine; Rats; RNA, Neoplasm; RNA, Transfer; Serine; Tritium; Tyrosine | 1971 |
Mechanisms in cellular metabolic regulation.
Topics: Animals; Animals, Newborn; Carcinoma, Hepatocellular; Cortisone; Dactinomycin; Diabetes Mellitus, Experimental; Diet; Fasting; Glucagon; Hydro-Lyases; Isoenzymes; L-Serine Dehydratase; Leucine; Liver; Liver Neoplasms; Models, Biological; Molecular Biology; Neoplasms, Experimental; Rats; RNA, Messenger; Tritium | 1971 |
Studies on the anti-tumour activity of aliphatic aldehydes. V. Preferential inhibition of protein synthesis in normal or neoplastic tissues in relation to molecular structure.
Topics: Aldehydes; Animals; Carcinoma, Hepatocellular; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Mice; Neoplasm Proteins; Neoplasms, Experimental; Oxygen Consumption; Protein Biosynthesis; Rats; Structure-Activity Relationship | 1972 |
Studies on rat liver catalase. V. Incorporation of 14 C-leucine into catalase by isolated rat liver ribosomes.
Topics: Acetamides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cell-Free System; Cycloheximide; Dactinomycin; Depression, Chemical; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nucleotides; Puromycin; Rats; Ribonucleases; Ribosomes; Triazoles | 1971 |
[The kinetics of marking nucleolar proteins. Demonostration of a rapidly marked fraction].
Topics: Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cell Line; Cell Nucleolus; Centrifugation, Density Gradient; Culture Media; Female; Kinetics; Leucine; Liver Neoplasms; Methods; Nucleoproteins; Proteins; Rats; RNA; RNA, Ribosomal; Time Factors; Tritium | 1972 |
Action of ethionine, methionine, ATP, adenine, albumin and Ca 2+ on protein synthesis of normal and tumor cells.
Topics: Adenine; Adenosine Triphosphate; Albumins; Amino Acids; Analysis of Variance; Animals; Calcium; Carbon Isotopes; Carcinoma, Hepatocellular; Cells; Edetic Acid; Ethionine; Female; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Methionine; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1972 |
Impaired synthesis of liver catalase in tumor-bearing rats.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cell-Free System; Chromatography, DEAE-Cellulose; Goats; Immunoassay; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Ribosomes | 1972 |
Polydeoxythymidylate inhibition of rabbit reticulocyte RNA dependent protein synthesis in a Krebs II ascites cell system.
Topics: Animals; Carcinoma, Hepatocellular; Carcinoma, Krebs 2; Cell-Free System; Culture Techniques; Depression, Chemical; Leucine; Liver Neoplasms; Neoplasm Proteins; Peptide Biosynthesis; Polynucleotides; Rabbits; Reticulocytes; RNA, Messenger; RNA, Neoplasm; Thymine Nucleotides; Tritium | 1972 |
Effect of neuraminic acid removal on the properties of a variant alkaline phosphatase in hepatoma.
Topics: Alkaline Phosphatase; Aminocaproates; Carcinoma, Hepatocellular; Edetic Acid; Enzyme Activation; Genetic Variation; Guanidines; Hot Temperature; Humans; Isoenzymes; Leucine; Liver Neoplasms; Neuraminic Acids; Neuraminidase; Phenylalanine; Phosphates; Urea | 1972 |
[Preparation of single cell suspensions from normal and regenerating rat liver and from Morris hepatoma 9121 and 5123 TC].
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Leucine; Liver; Liver Neoplasms; Liver Regeneration; Methods; Neoplasms, Experimental; Rats; Suspensions; Trypan Blue | 1972 |
Preparation of single-cell suspensions from normal liver, regenerating liver, and Morris hepatomas 9121 and 5123tc.
Topics: Animals; Boric Acids; Carbon Isotopes; Carcinoma, Hepatocellular; Cells, Cultured; Cytological Techniques; Edetic Acid; Female; Hyaluronoglucosaminidase; Leucine; Liver; Liver Neoplasms; Liver Regeneration; Male; Microbial Collagenase; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Protein Biosynthesis; Rats; Transplantation, Homologous; Trypan Blue | 1972 |
Effect of hydrocortisone on the synthesis of DNA and histones and the acetylation of histones in regenerating liver.
Topics: Acetates; Acylation; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Chromatography, Ion Exchange; DNA; Electrophoresis, Polyacrylamide Gel; Hepatectomy; Histones; Hydrocortisone; Leucine; Liver; Liver Neoplasms; Liver Regeneration; Male; Neoplasms, Experimental; Rats; Thymidine; Tritium | 1972 |
Studies on the inhibition by ethionine of aminoazo dye carcinogenesis in rat liver.
Topics: Administration, Oral; Animals; Appetite; Carbon Isotopes; Carcinoma, Hepatocellular; DNA, Neoplasm; Ethionine; Growth; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Proteins; Rats; Thymidine; Tritium | 1972 |
Increase of extravascular albumin pool and the intracellular accumulation of vesicles in transplanted Morris hepatoma 9121.
Topics: Albumins; Animals; Carcinoma, Hepatocellular; Endoplasmic Reticulum; Extracellular Space; Injections, Intravenous; Leucine; Liver; Liver Neoplasms; Microscopy, Electron; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Polyribosomes; Rats; Rats, Inbred ACI; Serum Albumin; Tissue Extracts; Transplantation, Homologous; Tritium; Ultrafiltration | 1972 |
Membrane fractions from rat hepatoma. II. Immunochemical characterization of detergent-soluble membrane esterases, glycosidases and leucyl- -naphthylamidase.
Topics: Allergy and Immunology; Amidohydrolases; Animals; Carcinoma, Hepatocellular; Cell Membrane; Electron Transport; Esterases; Female; Glucosidases; Immunodiffusion; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Membranes; Microsomes, Liver; Naphthalenes; Neoplasm Transplantation; Precipitin Tests; Rabbits; Rats; Transplantation, Homologous | 1973 |
In vitro synthesis rat serum lipoproteins and proteins by Morris hepatoma 7777.
Topics: Animals; Blood Proteins; Carbon Isotopes; Carcinoma, Hepatocellular; In Vitro Techniques; Leucine; Lipoproteins; Lipoproteins, HDL; Lipoproteins, VLDL; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats | 1972 |
In vitro synthesis of rat serum lipoproteins and proteins by Morris hepatoma 7777.
Topics: Animals; Blood Proteins; Carbon Isotopes; Carcinoma, Hepatocellular; In Vitro Techniques; Leucine; Lipoproteins; Lipoproteins, HDL; Lipoproteins, VLDL; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats | 1972 |
A comparative study of some properties of chromatin from two "minimal deviation" hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Chromatin; DNA-Directed RNA Polymerases; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Histones; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Proteins; Rats; RNA, Neoplasm; Spectrophotometry; Templates, Genetic; Tritium | 1973 |
Protein turnover in microsomal subfractions of liver and Morris hepatomas 7800 and 9618A.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cholesterol; Citrates; Diphosphates; Electrophoresis, Polyacrylamide Gel; Half-Life; Leucine; Liver; Liver Neoplasms; Male; Methods; Microsomes, Liver; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Phospholipids; Polytetrafluoroethylene; Proteins; Rats; Sodium Dodecyl Sulfate; Urea | 1973 |
Electrophoretic properties of the product of protein synthesis in mitochondria of rat liver and Zajdela hepatoma.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Fractionation; Electrophoresis, Polyacrylamide Gel; Female; Leucine; Liver Neoplasms; Male; Mitochondria, Liver; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Rats; Sodium Dodecyl Sulfate | 1973 |
Kinetic studies of a hepatoma alkaline phosphatase.
Topics: Alkaline Phosphatase; Amino Acids; Ascitic Fluid; Binding, Competitive; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Glycerophosphates; Humans; Kinetics; Leucine; Liver Neoplasms; Mathematics; Nitrophenols; Norleucine; Phenols; Phenylalanine; Phosphates; Tryptophan | 1973 |
Cellular differentiation and isozymes of branched-chain amino acid transaminase.
Topics: Adrenal Glands; Adrenalectomy; Aging; Animals; Brain; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line; Chromatography, DEAE-Cellulose; Diabetes Mellitus; Female; Hydrocortisone; Hypophysectomy; Isoenzymes; Kidney; Lactation; Leucine; Liver; Liver Neoplasms; Liver Regeneration; Mammary Glands, Animal; Molecular Weight; Organ Specificity; Pituitary Gland; Pregnancy; Rats; Transaminases | 1973 |
Immunoprecipitation is inappropriate for the isolation of radiochemically pure albumin from tissues.
Topics: Albumins; Animals; Antigen-Antibody Reactions; Antigens; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Evaluation Studies as Topic; Kidney; Leucine; Liver; Liver Neoplasms; Male; Methods; Neoplasms, Experimental; Rabbits; Rats; Serum Albumin; Serum Albumin, Bovine; Testis; Time Factors; Ultrafiltration | 1974 |
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.
Topics: Amino Acids; Animals; Arginine; Asparagine; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Culture Media; Cycloheximide; Drug Synergism; Glutamine; Glycine; Immune Sera; Leucine; Liver Neoplasms; Neoplasm Proteins; Ornithine; Proline; Pyridoxal; Rats; Serine; Stimulation, Chemical; Time Factors | 1974 |
Synthesis of alpha-fetoprotein by membrane-bound polysomes of rat ascites hepatoma cells.
Topics: Animals; Ascitic Fluid; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Fractionation; Cell Membrane; Cell-Free System; Fetal Proteins; Leucine; Liver Neoplasms; Male; Neoplasm Proteins; Neoplasms, Experimental; Polyribosomes; Rats | 1974 |
Protein and ribonucleic acid metabolism in single-cell suspensions from Morris hepatoma 5123tc and from normal rat liver.
Topics: Albumins; Animals; Anti-Bacterial Agents; Calcium; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Kinetics; Leucine; Liver; Liver Neoplasms; Magnesium; Methionine; Mitochondria, Liver; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Potassium; Protein Biosynthesis; Rats; RNA; RNA, Neoplasm; Transplantation, Homologous | 1974 |
Rapid degradation of puromycyl peptides in hepatoma cells and reticulocytes.
Topics: Animals; Blood Proteins; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, Gel; Cycloheximide; Drug Stability; Kinetics; Leucine; Liver Neoplasms; Neoplasm Proteins; Puromycin; Rabbits; Rats; Reticulocytes; Time Factors | 1974 |
Synthesis and degradation of the major hepatic phosphofructokinase isozyme in rat liver and hepatoma 3924-A.
Topics: Animals; Antigen-Antibody Reactions; Carbon Radioisotopes; Carcinoma, Hepatocellular; Isoenzymes; Isotope Labeling; Kinetics; Leucine; Liver; Liver Neoplasms; Neoplasms, Experimental; Phosphofructokinase-1; Protein Biosynthesis; Rabbits; Rats; Solubility; Time Factors; Tritium | 1974 |
The in vivo effects of leucine dehydrogenase from Bacillus sphaericus.
Topics: Amino Acid Oxidoreductases; Animals; Autoanalysis; Bacillus; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Hydrogen-Ion Concentration; Kinetics; Leucine; Liver; Liver Neoplasms; Mathematics; Mice; Mice, Inbred Strains; NAD; Neoplasms, Experimental; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
Changes in chromatin proteins during liver regeneration.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Chromatin; DNA; Electrophoresis, Disc; Hepatectomy; Histones; Isotope Labeling; Leucine; Liver; Liver Neoplasms; Liver Regeneration; Male; Neoplasms, Experimental; Nucleoproteins; Rats; RNA; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1974 |
The stimulatory effect of a serum factor on DNA and protein synthesis in hepatoma cells.
Topics: Animals; Blood Proteins; Carcinoma, Hepatocellular; Cells, Cultured; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Leucine; Liver; Liver Neoplasms; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Stimulation, Chemical; Thymidine; Time Factors; Transplantation, Homologous; Tritium | 1974 |
Cycloheximide inhibition of hypoxanthine transport cultured cells.
Topics: Adenine; Aminoisobutyric Acids; Animals; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Epithelium; Hypoxanthines; Kinetics; Leucine; Liver Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Pentosyltransferases; Puromycin; Rats; Sarcoma, Experimental; Time Factors | 1974 |
Further investigation of a variant of the placental alkaline phosphatase in human hepatic carcinoma.
Topics: Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Chromatography, Gel; Cross Reactions; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Humans; Hydrogen-Ion Concentration; Immunodiffusion; Isoenzymes; Leucine; Liver Neoplasms; Molecular Weight; Phenylalanine; Placenta; Rabbits; Tryptophan; Urea | 1974 |
Induction of tyrosine alpha-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line.
Topics: Aldosterone; Animals; Carcinoma, Hepatocellular; Culture Techniques; Cycloheximide; Dactinomycin; Desoxycorticosterone; Dexamethasone; Diethylstilbestrol; Enzyme Induction; Estradiol; Hydrocortisone; Leucine; Liver Neoplasms; Mitomycins; Progesterone; Puromycin; Rats; Steroids; Testosterone; Transaminases; Triamcinolone; Tyrosine Transaminase | 1966 |
"Superinduction" of tyrosine transaminase in hepatoma cell cultures: differential inhibition of synthesis and turnover by actionomycin D.
Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; Dactinomycin; Enzyme Induction; Hydrocortisone; Immunoassay; Leucine; Liver Neoplasms; RNA, Messenger; Tritium; Tyrosine Transaminase | 1968 |
Control of degradation and synthesis of induced tyrosine aminotransferase studied in hepatoma cells in culture.
Topics: Carcinoma, Hepatocellular; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Enzyme Induction; Hydrocortisone; Leucine; Liver Neoplasms; Neoplasms, Experimental; Tritium; Tyrosine Transaminase | 1969 |
Regulation of tyrosine alpha-ketoglutarate transaminase in rat liver. 8. Inductions by hydrocortisone and insulin in cultured hepatoma cells.
Topics: Adenylyl Cyclases; Animals; Antigen-Antibody Reactions; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Drug Synergism; Enzyme Induction; Glucagon; Hydrocortisone; Insulin; Insulin Antibodies; Kinetics; Leucine; Liver Neoplasms; Metabolism; Peptides; Rats; Time Factors; Tyrosine Transaminase | 1970 |
Tyrosine transaminase induction: differential effect of 5-azacytidine on liver and hepatoma 5123D.
Topics: Adrenalectomy; Animals; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Dactinomycin; Enzyme Induction; Hindlimb; Hydrocortisone; Kinetics; Leucine; Liver; Liver Neoplasms; Macromolecular Substances; Male; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; Ornithine; Protein Biosynthesis; Rats; Ribosomes; Sodium Chloride; Tyrosine Transaminase | 1971 |
Turnover of tyrosine transaminase in cultured hepatoma cells after inhibition of protein synthesis.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Enzyme Induction; Half-Life; Hydrocortisone; Immunochemistry; Kinetics; Leucine; Liver Neoplasms; Neoplasm Proteins; Puromycin; Time Factors; Tritium; Tyrosine Transaminase | 1971 |
The regulation of tyrosine aminotransferase synthesis. Studies in HTC cells with inhibitors of ribonucleic acid synthesis.
Topics: Benzimidazoles; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Drug Antagonism; Kinetics; Leucine; Liver Neoplasms; Metabolism; Neoplasm Proteins; Phosphates; Phosphorus Isotopes; Pyridines; RNA, Neoplasm; Sulfhydryl Compounds; Templates, Genetic; Tritium; Tyrosine Transaminase; Uridine | 1971 |
Regulation of phosphoenolpyruvate carboxykinase and tyrosine transaminase in hepatoma cell cultures. I. Effects of glucocorticoids, N 6 ,O 2' -dibutyryl cyclic adenosine 3',5'-monophosphate and insulin in Reuber H35 cells.
Topics: Antibody Formation; Butyrates; Carboxy-Lyases; Carcinoma, Hepatocellular; Cells, Cultured; Culture Media; Cyclic AMP; Cycloheximide; Dexamethasone; Drug Interactions; Enzyme Induction; Glucagon; Humans; Hydrocortisone; Insulin; Isoproterenol; Leucine; Liver Neoplasms; Neoplasms, Experimental; Phosphoenolpyruvate; Progesterone; Stimulation, Chemical; Time Factors; Tritium; Tyrosine Transaminase | 1971 |
Regulation of tyrosine- -ketoglutarate transaminase in rat liver.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Induction; Fluorine; Half-Life; Hydrocortisone; Immunodiffusion; Insulin; Keto Acids; Kinetics; Leucine; Liver Neoplasms; Rats; Serine; Stereoisomerism; Tritium; Tyrosine Transaminase | 1971 |
Evidence for translational regulation of specific enzyme synthesis by N 6 , O 2' -dibutyryl cyclic AMP in hepatoma cell cultures.
Topics: Butyrates; Carboxy-Lyases; Carcinoma, Hepatocellular; Cyclic AMP; Dactinomycin; Dexamethasone; Enzyme Induction; Kinetics; Leucine; Liver Neoplasms; Oxaloacetates; Phosphoenolpyruvate; Precipitin Tests; RNA, Neoplasm; Tritium; Tyrosine Transaminase; Uridine | 1972 |
Degradation of messenger RNA in mammalian cells.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Depression, Chemical; Enzyme Induction; Half-Life; Hydrocortisone; Leucine; Liver; Liver Neoplasms; Methods; Molecular Biology; Protein Biosynthesis; Puromycin; Radioimmunoassay; Rats; Ribosomes; RNA, Messenger; Time Factors; Tyrosine Transaminase | 1972 |
Static and dynamic aspects of amino acid pools in rat liver and Morris hepatomas 9618A and 7800.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Kinetics; Leucine; Liver; Liver Neoplasms; Lysine; Male; Microsomes, Liver; Neoplasm Proteins; Neoplasms, Experimental; Proteins; Rats | 1974 |
In vitro DL-1- 14 C leucine incorporation into protein of rat liver slices during hepatic carcinogenesis induced by DAB in the presence and in the absence of albumin.
Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Isotopes; Diet; Dietary Proteins; Female; In Vitro Techniques; Leucine; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Riboflavin; Serum Albumin, Bovine; Stimulation, Chemical | 1972 |
[Branched chain amino acid transaminase isozymes in various cancer cells and in the process of oncogenesis].
Topics: Animals; Antibodies; Brain; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis; Immunodiffusion; Isoenzymes; Isoleucine; Leucine; Liver Neoplasms; Male; Neoplasms, Experimental; Neutralization Tests; Rats; Sarcoma, Yoshida; Transaminases; Ultracentrifugation; Valine | 1971 |
[Arylamidase and its isoenzymes in diseases of the pancreas and liver].
Topics: Acute Disease; Agar; Alanine; Alkaline Phosphatase; Amides; Aminohydrolases; Anilides; Cholestasis; Chronic Disease; Electrophoresis; Hepatitis; Humans; Isoenzymes; Leucine; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Naphthalenes; Nitro Compounds; Pancreatic Diseases; Pancreatitis | 1971 |
[Clinical studies on serum leucyl glycyl glycine hydrolyzing enzyme in cancer. II].
Topics: Adult; Aged; Amino Acids; Aminopeptidases; Female; Glycine; Humans; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Male; Neoplasms; Peptide Hydrolases; Peptides; Pregnancy; Protease Inhibitors; Stomach Neoplasms | 1971 |
Amino acid naphthylamidase isozymes in cancer cells and normal cells.
Topics: Aged; Aminopeptidases; Autopsy; Cell Line; Cells, Cultured; Copper; Electrophoresis; Female; Gels; Humans; Isoenzymes; Leucine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Middle Aged; Naphthalenes; Neoplasm Metastasis; Neoplasms; Starch; Tissue Extracts | 1971 |
Cytoplasmic inheritance in metazoa and its relationship to cell phenotype. 3. Uptake of mouse liver cell fractions by 6C3HED lymphosarcoma cells in vitro.
Topics: Animals; Carbon Isotopes; Cell Transformation, Neoplastic; Centrifugation; Culture Techniques; Female; Histocytochemistry; Leucine; Liver Neoplasms; Lymphoma, Non-Hodgkin; Mice; Mitochondria, Liver; Neoplasm Transplantation; Neoplasms, Experimental; Organoids; Phenotype | 1970 |
[On the behavior of the so-called leucine aminopeptidase (LAP) in the serum during the application of various substrates].
Topics: Adolescent; Adult; Aged; Animals; Aspartate Aminotransferases; Biliary Tract Diseases; Cholestasis; Female; Glycine; Humans; Leucine; Leucyl Aminopeptidase; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Myocardial Infarction; Neoplasm Metastasis; Pancreatic Neoplasms; Rats | 1968 |
Incorporation of L-[14C]leucine into the nucleoli of mouse ascites tumor cells.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Cell Nucleolus; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; Guanine Nucleotides; Kinetics; Leucine; Liver Neoplasms; Magnesium; Mice; Microsomes; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Ribonucleases; RNA, Transfer; Time Factors | 1969 |