leucine has been researched along with Leukemia in 49 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 36 (73.47) | 18.7374 |
1990's | 7 (14.29) | 18.2507 |
2000's | 4 (8.16) | 29.6817 |
2010's | 2 (4.08) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Li, CX; Shen, SM; Wang, LS; Yu, Y | 1 |
Crouthamel, MH; Ho, RJ; Wu, D; Yang, Z | 1 |
Hamatani, S; Imai, T; Isobe, K; Itoh, S; Kuromi, T; Nanba, M; Nomi, K; Okada, H | 1 |
BAKER, WH; STEPHENSON, ML; ZAMECNIK, PC | 1 |
BEATTY, EC; HYMAN, CP; MURPHY, ML; PHERCE, MI; SEVERO, NC; SULLIVAN, MP | 1 |
AGOSTONI, A; DIOGUARDI, N; FIORELLI, G; IDEO, G; TITTOBELLO, A | 1 |
HEYWOOD, JD; KARON, M; WEISSMAN, S | 1 |
BARNABEI, O; BUDILLON, G; COLTORTI, M; PAPA, S; QUAGLIARIELLO, E | 1 |
ANKER, HS; RENNERT, OM | 1 |
GAVOSTO, F; MARAINI, G; PILERI, A | 1 |
Bayly, R; Casselman, R; Hyndman, BD; LeBrun, DP; Munro, K; Murase, T; Nurmohamed, S; Savage, R; Smith, SP | 1 |
Kimura, M | 1 |
Fewtrell, C; Metzger, H; Perez-Montfort, R | 1 |
Basala, M; Raso, V | 1 |
Kurita, S; Massaoka, T; Ogawa, N; Ota, K; Uzuka, Y; Yamada, K | 1 |
Ochi, T; Ohsawa, M; Takahashi, K | 1 |
Arimori, S; Komatsuda, M; Nagao, T; Shimizu, Y; Watanabe, K | 1 |
Kanno, T | 1 |
Abe, F; Fujii, H; Sekine, K | 1 |
Keppler-Hafkemeyer, A; Kreitman, RJ; Pastan, I | 1 |
Hatake, K; Hayasawa, H; Ikeda, K; Ishizaka, Y; Katsuyama, M; Matsumoto-Mishima, Y; Mishima, Y; Mizunuma, N; Mori, M; Terui, Y; Watanabe, J; Yamada, M | 1 |
Frengley, PA; Lichtman, MA; Peck, WA | 1 |
Lange Wantzin, G | 1 |
Caligaris, F; Marinone, C; Masera, P; Matera, L | 1 |
Farkas, WR | 1 |
Labie, D; Pagnier, J | 1 |
Ota, K; Uzuka, Y | 1 |
Chiba, S; Hino, M; Kitamura, T; Miyagawa, K; Miyazano, K; Shibuya, K; Takaku, F | 1 |
Cornelius, AS; Kratz, DA; Spector, AA; Yerram, NR | 1 |
Fukutani, H; Kimura, I; Miura, Y; Mizoguchi, H; Naoe, T; Ohno, R; Ohshima, T; Omine, M; Saito, H; Tomonaga, M | 1 |
Abe, K; Imamura, M; Kasai, M; Kobayashi, M; Morioka, M; Okabe, M; Sakurada, K; Sugiura, T; Tachibana, N; Tanaka, M | 1 |
Hiraoka, A | 1 |
Tsukagoshi, S | 1 |
Kurita, S; Masaoka, T; Ogawa, N; Ota, K; Uzuka, Y; Yamada, K | 2 |
Blinov, MN; Filanovskaia, LI; Togo, AV | 1 |
Chou, TC; Holland, JF; Ohnuma, T; Okano, T; Takemura, Y | 1 |
Kotlarek-Haus, S | 1 |
Jarrett, O | 1 |
Gross, J; Rachmilewitz, B; Rachmilewitz, M | 2 |
Apple, MA; Cline, MJ | 1 |
Bernardelli, R; Brusa, L; Gavosto, F; Pileri, A; Tarocco, RP | 1 |
Stacher, A; Stöckl, W; Weiser, M; Zacherl, MK | 1 |
Gallo, RC | 1 |
Kaplan, JG; Quastel, MR | 1 |
Todo, A | 1 |
Bachi, C; Gavosto, F; Pegoraro, L; Pileri, A | 2 |
1 review(s) available for leucine and Leukemia
Article | Year |
---|---|
Clinical trials of bestatin for leukemia and solid tumors.
Topics: Humans; Immunologic Factors; Leucine; Leukemia; Neoplasms | 1992 |
5 trial(s) available for leucine and Leukemia
Article | Year |
---|---|
[Immunotherapy with bestatin for acute non-lymphocytic leukemia (ANLL) in adults].
Topics: Acute Disease; Adjuvants, Immunologic; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Female; Humans; Leucine; Leukemia; Male; Middle Aged | 1984 |
Clinical trials of bestatin for leukemia and solid tumors.
Topics: Humans; Immunologic Factors; Leucine; Leukemia; Neoplasms | 1992 |
Treatment of myelodysplastic syndromes with orally administered N-(2S, 3R)-3-amino-2-hydroxy-4-phenylbutyryl-L-leucine (ubenimex).
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aminopeptidases; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Child; Female; Humans; Leucine; Leukemia; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies | 1991 |
Immunotherapy with bestatin for acute nonlymphocytic leukemia in adults.
Topics: Acute Disease; Adjuvants, Immunologic; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Female; Humans; Leucine; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Random Allocation | 1986 |
[Results of follow-up studies on prognosis after immunotherapy with bestatin in acute nonlymphocytic leukemia].
Topics: Aclarubicin; Acute Disease; Adjuvants, Immunologic; Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leucine; Leukemia; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone; Prognosis; Random Allocation | 1986 |
44 other study(ies) available for leucine and Leukemia
Article | Year |
---|---|
Caspase-3-resistant uncleavable form of acidic leucine-rich nuclear phosphoprotein 32B potentiates leukemic cell apoptosis.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Gene Expression; Humans; Leucine; Leukemia; Mutation; Nuclear Proteins; Protein Interaction Domains and Motifs; Protein Kinase C-delta; Proteolysis; Proto-Oncogene Proteins c-bcl-2 | 2015 |
A novel MDR1 GT1292-3TG (Cys431Leu) genetic variation and its effect on P-glycoprotein biologic functions.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line; Cysteine; Genetic Variation; Humans; Leucine; Leukemia; Mutation; Plasmids; Rhodamine 123 | 2010 |
Induction of graft-versus-host disease and a graft-versus-leukemia effect using ubenimex in a patient with infantile leukemia relapsing after an unrelated cord blood transplant.
Topics: Cord Blood Stem Cell Transplantation; Graft vs Host Disease; Graft vs Leukemia Effect; Humans; Infant; Leucine; Leukemia; Male; Recurrence; Remission Induction; Transplantation, Homologous | 2002 |
In vitro incorporation of C14-DL-leucine into normal and leukemic white cells.
Topics: In Vitro Techniques; Leucine; Leukemia | 1957 |
A comparison of the effectiveness of standard dose 6-mercaptopurine, combination 6-mercaptopurine and DON, and high-loading 6-mercaptopurine therapies in the treatment of acute leukemia in children: results of cooperative study.
Topics: Acute Disease; Antineoplastic Agents; Biomedical Research; Child; Humans; Infant; Leucine; Leukemia; Mercaptopurine | 1962 |
CHROMATOGRAPHIC STUDIES ON LEUCINE AMINOPEPTIDASE IN NORMAL HUMAN GRANULOCYTES AND IN CELLS OF ACUTE AND CHRONIC MYELOID LEUKEMIA.
Topics: Aminopeptidases; Blood Chemical Analysis; Chromatography; Granulocytes; Humans; Leucine; Leucyl Aminopeptidase; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukocytes | 1963 |
AMINO ACIDS: INCORPORATION INTO ALPHA- AND BETA-CHAINS OF HEMOGLOBIN BY NORMAL AND THALASSEMIC RETICULOCYTES.
Topics: Amino Acids; Anemia, Sickle Cell; Carbon Isotopes; Globins; Hemoglobins; Humans; Leucine; Leukemia; Proteins; Research; Reticulocytes; Thalassemia; Valine | 1964 |
PROTEIN SYNTHESIS IN THE SPLEEN OF MICE INFECTED WITH FRIEND VIRUS.
Topics: Adenosine Triphosphate; Blood Proteins; Friend murine leukemia virus; Leucine; Leukemia; Leukemia Virus, Murine; Leukemia, Experimental; Liver; Mice; Oncogenic Viruses; Pharmacology; Protein Biosynthesis; Protein Hydrolysates; Proteins; Puromycin; Pyruvates; Research; Spleen; Threonine; Virus Diseases | 1964 |
EFFECT OF 5',5',5'-TRIFLUOROLEUCINE ON A NUMBER OF MOUSE LEUKAEMIAS.
Topics: Amino Acids; Animals; Chromatography; Hair; Leucine; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Liver; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Pharmacology; Proteins; Research; Skin | 1964 |
[Incorporation of tritium-labeled DL-leucine into the blood cells in acute leukosis and in chronic myeloid leukemia].
Topics: Blood Cells; Humans; Leucine; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Tritium | 1960 |
Critical role for a single leucine residue in leukemia induction by E2A-PBX1.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Transformation, Neoplastic; CREB-Binding Protein; Female; Homeodomain Proteins; Humans; Leucine; Leukemia; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Myeloid Cells; NIH 3T3 Cells; Oncogene Proteins, Fusion; Protein Binding; Protein Interaction Mapping; Protein Structure, Tertiary; Thermodynamics | 2006 |
[Autoradiographic studies on DNA, RNA and protein synthesis in vitro of human bone marrow cells].
Topics: Anemia; Autoradiography; Bone Marrow; Bone Marrow Cells; DNA; Humans; In Vitro Techniques; Leucine; Leukemia; Proteins; RNA; Thymidine; Tritium; Uridine | 1966 |
Changes in the receptor for immunoglobulin E coincident with receptor-mediated stimulation of basophilic leukemia cells.
Topics: Animals; Basophils; Cell Line; Exocytosis; Leucine; Leukemia; Macromolecular Substances; Mast Cells; Molecular Weight; Phosphates; Rats; Receptors, IgE; Receptors, Immunologic | 1983 |
A highly cytotoxic human transferrin-ricin A chain conjugate used to select receptor-modified cells.
Topics: Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leucine; Leukemia; Receptors, Cell Surface; Receptors, Transferrin; Ricin; Time Factors; Transferrin | 1984 |
A mechanism for the stimulation by inorganic mercury of [3H] thymidine incorporation into DNA in cultured Molt-4F cells.
Topics: Cell Line; DNA, Neoplasm; Humans; Leucine; Leukemia; Mercury; Methotrexate; T-Lymphocytes; Thymidine; Thymidine Kinase; Tritium | 1983 |
The effect of bestatin on patients with acute and chronic leukemia and malignant lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Female; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Male; Middle Aged | 1980 |
[Leucinamide specific cytosol leucine aminopeptidase].
Topics: Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Cytosol; Humans; Leucine; Leucyl Aminopeptidase; Leukemia; Lymphoma; Substrate Specificity | 1982 |
Induction of apoptosis by bestatin (ubenimex) in human leukemic cell lines.
Topics: Aminopeptidases; Apoptosis; Caspase 3; Caspases; CD13 Antigens; Cell Division; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Leucine; Leukemia; Protease Inhibitors; Tumor Cells, Cultured | 1999 |
Apoptosis induced by immunotoxins used in the treatment of hematologic malignancies.
Topics: Amino Acid Chloromethyl Ketones; Antibodies; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Apoptosis; Burkitt Lymphoma; Caspase 3; Caspases; Cell Adhesion Molecules; Cell Survival; Coumarins; DNA Fragmentation; Dose-Response Relationship, Drug; Hematologic Neoplasms; Immunoblotting; Immunotoxins; Lectins; Leucine; Leukemia; Lymphoma, T-Cell; Oligopeptides; Protease Inhibitors; Recombinant Proteins; Sialic Acid Binding Ig-like Lectin 2; Tetrazolium Salts; Tumor Cells, Cultured | 2000 |
Leukemic cell-surface CD13/aminopeptidase N and resistance to apoptosis mediated by endothelial cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; Blotting, Northern; CD13 Antigens; Cell Division; Cells, Cultured; Endothelium, Vascular; Fluorescent Antibody Technique; Humans; In Situ Nick-End Labeling; Interleukin-8; K562 Cells; Leucine; Leukemia; Transfection; Umbilical Veins | 2002 |
Adaptive enhancement of amino acid transport in human leukemia leukocytes: studies with alpha-aminoisobutyric acid.
Topics: Acute Disease; Adenosine Triphosphate; Aminoisobutyric Acids; Cell Membrane; Cyclic AMP; Cycloheximide; Dactinomycin; Extracellular Space; Humans; Intracellular Fluid; Kinetics; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Proteins; Time Factors | 1975 |
Leucine incorporation into leukaemic blast cells.
Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Female; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Protein Biosynthesis; Puromycin; Thymidine | 1979 |
An approach to simultaneous immunofluorescent and autoradiographic analysis of human normal and neoplastic blood cells.
Topics: Adult; Autoradiography; Bone Marrow; Fluorescent Antibody Technique; Humans; Infectious Mononucleosis; Leucine; Leukemia; Lymph Nodes; Lymphocytes; Lymphoma; Thymidine; Uridine | 1977 |
The effects of plumbous ion on protein biosynthesis in reticulocytes.
Topics: Amino Acids; Animals; Bacterial Proteins; Blood Proteins; Carbon Radioisotopes; Cell-Free System; Escherichia coli; Globins; HeLa Cells; Hemoglobins; Humans; Lead; Leucine; Leukemia; Proteins; Rabbits; Reticulocytes; RNA, Messenger; Sheep; Time Factors; Triticum; Tritium | 1975 |
Abnormal hemoglobin synthesis in some leukemic patients.
Topics: Carbon Radioisotopes; Chromatography, Gel; Fetal Hemoglobin; Globins; Hemoglobins, Abnormal; Humans; Leucine; Leukemia; Lysine; Reticulocytes; Tritium | 1975 |
Enhancing effect of ubenimex (bestatin) on proliferation and differentiation of hematopoietic progenitor cells, and the suppressive effect on proliferation of leukemic cell lines via peptidase regulation.
Topics: Aminopeptidases; Animals; Antibiotics, Antineoplastic; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; Leucine; Leukemia; Mice | 1991 |
Cytotoxic effect of cis-parinaric acid in cultured malignant cells.
Topics: Butylated Hydroxytoluene; Cell Differentiation; Cell Survival; Fatty Acids, Unsaturated; Humans; Leucine; Leukemia; Stereoisomerism; Tumor Cells, Cultured | 1991 |
Inhibitory effect of bestatin on the growth of human leukemic cells.
Topics: Antibiotics, Antineoplastic; B-Lymphocytes; Cell Division; Dose-Response Relationship, Drug; Humans; Leucine; Leukemia; Microscopy, Electron, Scanning; T-Lymphocytes; Tumor Cells, Cultured | 1990 |
[Control of graft-vs-host disease].
Topics: Adolescent; Adult; Bone Marrow Transplantation; Female; Graft vs Host Disease; Guanidines; Humans; Leucine; Leukemia; Male; Methylprednisolone; Ribonucleosides | 1990 |
[A new antitumor drug with immunomodulating activity, ubenimex (bestatin)].
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Animals; Female; Humans; Leucine; Leukemia; Leukemia P388; Leukemia, Myeloid; Lymphoma; Male; Mice; Middle Aged; T-Lymphocytes | 1987 |
[Effect of purine nucleosides on human leukocytes in normal conditions and in leukemias].
Topics: Blood Proteins; Cell Division; Granulocytes; Humans; In Vitro Techniques; Leucine; Leukemia; Leukocytes; Lymphocytes; Neoplasm Proteins; Purine Nucleosides | 1987 |
Biologic and pharmacologic effects of harringtonine on human leukemia-lymphoma cells.
Topics: Alkaloids; Cell Line; Dose-Response Relationship, Drug; Harringtonines; Humans; Leucine; Leukemia; Lymphoma; Time Factors; Tritium | 1985 |
[Behavior of aminopeptidase activity in human leukemic leukocytes].
Topics: Acyltransferases; Adolescent; Adult; Aged; Aminopeptidases; Aspartic Acid; Child; Clinical Enzyme Tests; Eosinophils; Female; Glutamine; Glycine; Histocytochemistry; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Naphthols; Peptide Hydrolases | 1971 |
Antigenic determinants shared by polypeptides of feline leukaemia virus.
Topics: Amino Acids; Animals; Antibodies, Viral; Antigens, Viral; Carbon Radioisotopes; Cats; Cross Reactions; Electrophoresis, Polyacrylamide Gel; Epitopes; Immune Sera; Leucine; Leukemia; Leukemia Virus, Feline; Molecular Weight; Peptides; Precipitin Tests; Rabbits; Sodium Dodecyl Sulfate; Tritium; Viral Proteins | 1973 |
A vitamin B12 binder with transcobalmin I characteristics synthesized and released by human granulocytes in vitro.
Topics: Biological Assay; Blood Proteins; Chromatography; Cobalt Radioisotopes; Humans; In Vitro Techniques; Kinetics; Leucine; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Protein Binding; Tritium; Vitamin B 12 | 1974 |
[Production of B12-binding protein by human leukocytes in vitro].
Topics: Carrier Proteins; Cobalt Isotopes; Humans; In Vitro Techniques; Leucine; Leukemia; Leukocytes; Methods; Protein Binding; Time Factors; Tritium; Vitamin B 12 | 1972 |
Anticancer effects of propanals: comparison between human and animal tumor systems.
Topics: Aldehydes; Animals; Antineoplastic Agents; Carbohydrate Metabolism; Carbon Isotopes; DNA, Neoplasm; Glyceraldehyde; Humans; In Vitro Techniques; Leucine; Leukemia; Leukemia, Experimental; Leukocytes; Mice; Neoplasm Proteins; Oxygen Consumption; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1971 |
Degradation of RNA and changes in protein metabolism in human acute leukaemia cells treated with actinomycin D.
Topics: Dactinomycin; Humans; Leucine; Leukemia; Leukemia, Myeloid, Acute; Proteins; RNA; Time Factors; Tritium; Uridine | 1967 |
[Behavior of free amino acids in the blood of leukemia patients following amino acid infusion].
Topics: Adult; Aged; Amino Acids; Arginine; Female; Glycine; Histidine; Humans; Infusions, Parenteral; Isoleucine; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Lysine; Male; Methionine; Phenylalanine; Threonine; Tryptophan; Valine | 1968 |
Transfer RNA's in human leukemia.
Topics: Amino Acid Sequence; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Chromatography; Humans; Leucine; Leukemia; Lymphocyte Activation; Lymphocytes; Methylation; RNA, Neoplasm; RNA, Transfer; Time Factors; Tyrosine | 1969 |
Lymphocyte stimulation: the effect of ouabain on nucleic acid and protein synthesis.
Topics: Animals; Autoradiography; Culture Techniques; DNA; Hydrocortisone; Lectins; Leucine; Leukemia; Lymphocyte Activation; Lymphocytes; Methionine; Methods; Ouabain; Potassium; Prednisolone; Protein Biosynthesis; RNA; Thymidine; Time Factors; Tritium; Uridine | 1970 |
Proliferation and differentiation of hematopoietic cells in hematologic disorders. II. In vitro radioautographic study of leukemic cells.
Topics: Adult; Aged; Culture Techniques; Female; Hematopoiesis; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Thymidine; Tritium; Uridine | 1968 |
[Influence of normal and leukemic RNA on the protein metabolism of acute leukemic cells].
Topics: Autoradiography; Blood Cells; Bone Marrow; Bone Marrow Cells; Humans; In Vitro Techniques; Leucine; Leukemia; Proteins; RNA; Tritium | 1965 |
[Stimulation of the protein metabolism of cells in acute human leukemia by native ribonucleic acid extracted from normal human bone marrow].
Topics: Blood Cells; Bone Marrow; Bone Marrow Cells; Humans; Leucine; Leukemia; RNA | 1964 |