leucine and Leukemia, Myeloid, Acute

leucine has been researched along with Leukemia, Myeloid, Acute in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199021 (58.33)18.7374
1990's9 (25.00)18.2507
2000's2 (5.56)29.6817
2010's3 (8.33)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Jiang, L; Ma, W; Tong, T; Wang, J; Wang, S; Wu, J; Xu, X; Zhang, W; Zhao, M; Zhou, D1
Huang, L; Wang, D; Wang, T; Xi, Y; Zhang, XE1
Bănescu, C; Benedek Lazar, E; Cândea, M; Crauciuc, A; Dobreanu, M; Duicu, C; Iancu, M; Moldovan, VG; Trifa, AP; Tripon, F1
Adachi, Y; Kimura, Y; Kiyoi, H; Komatsu, H; Kubo, K; Miyawaki, S; Miyazaki, Y; Naoe, T; Ohnishi, K; Ohno, R; Ohtake, S; Takada, S; Takeshita, A; Ueda, R; Wakita, A; Yagasaki, F; Yamaguchi, T; Yoshida, M1
Chiba, H; Hirayama, Y; Matsunaga, T; Niitsu, Y; Sagawa, T; Sakamaki, S; Takayanagi, N; Tsuji, Y1
de Koning, BA; de Laat, PC; Pieters, R; van der Schoor, SR; van Goudoever, JB; Wattimena, DL1
Bloch, A; Craig, RW; Frankfurt, OS; Sakagami, H; Takeda, K1
Arimori, S; Komatsuda, M; Nagao, T; Shimizu, Y; Watanabe, K1
Colbert, DA; Deisseroth, AB; Fontana, JA1
Mizoguchi, H; Mutoh, Y; Ogawa, N; Takaku, F; Urabe, A1
Ito, S; Miyairi, Y; Murai, K; Narigasawa, Y; Numaoka, H; Oikawa, H; Ono, Y; Shimosegawa, K; Sugawara, T; Utsugisawa, T1
Abe, F; Fujii, H; Maruyama, S; Yosizawa, K1
Schelen, AM; Touw, IP; van Aesch, YM; Ward, AC1
Frengley, PA; Lichtman, MA; Peck, WA1
Lange Wantzin, G1
Karle, H; Killmann, SA; Philip, P; Wantzin, GL1
Hiraoka, A; Masaoka, T; Shibata, H1
Catovsky, D; Gill, R; Levi, S; Marshall, CJ; Matutes, E; Urbano-Ispizua, A; Wiedemann, LM1
Ota, K1
Ogawa, N; Ota, K1
Ishikawa, T; Nagai, K; Nakayama, S; Yabe, H1
Hreniuk, D; Lenard, J; Wilson, PD1
Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H1
Malvoisin, E; Wild, F; Zwingelstein, G1
Miura, K; Sawa, T; Takeuchi, T; Umezawa, H1
Compagnoni, G; Falda, M; Genazzani, E; Infelise, V; Lovisone, E; Silvestro, L; Viano, I1
Mishina, H; Okuyama, S1
Kotlarek-Haus, S1
Gross, J; Rachmilewitz, B; Rachmilewitz, M1
Jacobs, A; Parry, DH; White, GP; Worwood, M1
Chan, BW2
Clarkson, B; Fried, J; Ohkita, T; Ota, K1
Emilia, G; Grossi, G; Quaglino, D; Sauli, S1
Bernardelli, R; Brusa, L; Gavosto, F; Pileri, A; Tarocco, RP2

Reviews

1 review(s) available for leucine and Leukemia, Myeloid, Acute

ArticleYear
Review of ubenimex (Bestatin): clinical research.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1991, Volume: 45, Issue:2-3

    Topics: Adolescent; Adult; Age Factors; Antibiotics, Antineoplastic; Humans; Leucine; Leukemia, Myeloid, Acute; Middle Aged; Neoplasms; Prospective Studies

1991

Trials

6 trial(s) available for leucine and Leukemia, Myeloid, Acute

ArticleYear
Randomized comparison of fixed-schedule versus response-oriented individualized induction therapy and use of ubenimex during and after consolidation therapy for elderly patients with acute myeloid leukemia: the JALSG GML200 Study.
    International journal of hematology, 2012, Volume: 96, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Female; Humans; Induction Chemotherapy; Leucine; Leukemia, Myeloid, Acute; Male; Survival Analysis; Treatment Outcome

2012
Chemotherapy does not influence intestinal amino acid uptake in children.
    Pediatric research, 2007, Volume: 62, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Breath Tests; Carbon Dioxide; Carbon Isotopes; Child; Child, Preschool; Diarrhea; Enteral Nutrition; Humans; Infant; Intestinal Absorption; Leucine; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, B-Cell; Severity of Illness Index; Splanchnic Circulation; Stomatitis; Treatment Outcome

2007
Ubenimex in the treatment of acute nonlymphocytic leukemia in adults.
    Annals of hematology, 1993, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leucine; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1993
Immunopotentiation with Ubenimex for prevention of leukemia relapse after allogeneic BMT. The Study Group of Ubenimex for BMT.
    Transplantation proceedings, 1992, Volume: 24, Issue:6

    Topics: Adjuvants, Immunologic; Administration, Oral; Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Chronic Disease; Female; Graft vs Host Disease; Graft vs Host Reaction; Humans; Infant; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Recurrence

1992
Review of ubenimex (Bestatin): clinical research.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1991, Volume: 45, Issue:2-3

    Topics: Adolescent; Adult; Age Factors; Antibiotics, Antineoplastic; Humans; Leucine; Leukemia, Myeloid, Acute; Middle Aged; Neoplasms; Prospective Studies

1991
Randomized controlled study of chemoimmunotherapy with bestatin of acute nonlymphocytic leukemia in adults.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1990, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Drug Evaluation; Female; Follow-Up Studies; Humans; Leucine; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1990

Other Studies

30 other study(ies) available for leucine and Leukemia, Myeloid, Acute

ArticleYear
A self-assembled leucine polymer sensitizes leukemic stem cells to chemotherapy by inhibiting autophagy in acute myeloid leukemia.
    Haematologica, 2022, 10-01, Volume: 107, Issue:10

    Topics: Animals; Autophagy; Doxorubicin; Leucine; Leukemia, Myeloid, Acute; Mice; Neoplastic Stem Cells; Polymers; TOR Serine-Threonine Kinases

2022
Quantitative profiling of CD13 on single acute myeloid leukemia cells by super-resolution imaging and its implication in targeted drug susceptibility assessment.
    Nanoscale, 2019, Jan-23, Volume: 11, Issue:4

    Topics: Antibodies; Apoptosis; CD13 Antigens; Cell Cycle Checkpoints; Cell Line, Tumor; Humans; Leucine; Leukemia, Myeloid, Acute; Microscopy, Confocal; Quantum Dots

2019
From Six Gene Polymorphisms of the Antioxidant System, Only GPX Pro198Leu and GSTP1 Ile105Val Modulate the Risk of Acute Myeloid Leukemia.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Adult; Aged; Antioxidants; Case-Control Studies; Female; Gene Expression Regulation, Leukemic; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoleucine; Leucine; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Mutation; Polymorphism, Genetic; Proline; Reactive Oxygen Species; Risk; Romania; Superoxide Dismutase; Valine

2016
[Chemotherapy with ubenimex corresponding to patient age and organ disorder for 18 cases of acute myelogeneous leukemia in elderly patients--effects, complications and long-term survival].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:8

    Topics: Aclarubicin; Age Factors; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leucine; Leukemia, Myeloid, Acute; Male; Remission Induction; Survival Rate

2003
Macromolecular and cell cycle effects of different classes of agents inducing the maturation of human myeloblastic leukemia (ML-1) cells.
    Cancer research, 1984, Volume: 44, Issue:6

    Topics: Cell Cycle; Cell Differentiation; Cell Line; Cycloheximide; Cytarabine; Dactinomycin; Daunorubicin; DNA Replication; Humans; Kinetics; Leucine; Leukemia, Myeloid, Acute; Protein Biosynthesis; Thymidine; Transcription, Genetic; Tretinoin; Tritium; Uridine

1984
The effect of bestatin on patients with acute and chronic leukemia and malignant lymphoma.
    The Tokai journal of experimental and clinical medicine, 1980, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Female; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Male; Middle Aged

1980
Identification of a population of bipotent stem cells in the HL60 human promyelocytic leukemia cell line.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:6

    Topics: Cell Differentiation; Cell Line; Cells, Cultured; Clone Cells; Dimethylformamide; Hematopoietic Stem Cells; Humans; Kinetics; Leucine; Leukemia, Myeloid, Acute; Macrophages; Tetradecanoylphorbol Acetate

1981
[Hematological stability under ubenimex monotherapy in a patient with acute myelogenous leukemia developing marrow karyotypic changes during the course].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:11

    Topics: Aged; Antibiotics, Antineoplastic; Bone Marrow Cells; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 8; Female; Humans; Karyotyping; Leucine; Leukemia, Myeloid, Acute; Mutagenesis, Insertional; Trisomy

1995
[Growth inhibitory effects of ubenimex on leukemic cell lines resistant to chemotherapeutic agents].
    The Japanese journal of antibiotics, 1996, Volume: 49, Issue:12

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Division; Cytarabine; Daunorubicin; Depression, Chemical; Drug Combinations; Drug Resistance, Neoplasm; Drug Synergism; Humans; Leucine; Leukemia, Myeloid, Acute; Mercaptopurine; Tumor Cells, Cultured

1996
Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia.
    Blood, 1999, Jan-15, Volume: 93, Issue:2

    Topics: Animals; Cytochalasin D; DNA Mutational Analysis; DNA-Binding Proteins; Granulocyte Colony-Stimulating Factor; Humans; Leucine; Leukemia, Myeloid, Acute; Mice; Milk Proteins; Mutagenesis, Site-Directed; Mutation; Neutropenia; Receptors, Granulocyte Colony-Stimulating Factor; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Structure-Activity Relationship; Trans-Activators; Tumor Cells, Cultured; Tyrosine

1999
Adaptive enhancement of amino acid transport in human leukemia leukocytes: studies with alpha-aminoisobutyric acid.
    The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:6

    Topics: Acute Disease; Adenosine Triphosphate; Aminoisobutyric Acids; Cell Membrane; Cyclic AMP; Cycloheximide; Dactinomycin; Extracellular Space; Humans; Intracellular Fluid; Kinetics; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Proteins; Time Factors

1975
Leucine incorporation into leukaemic blast cells.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1979, Volume: 31, Issue:6

    Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Female; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Protein Biosynthesis; Puromycin; Thymidine

1979
The effect of daunomycin on cell proliferation and protein synthesis of human leukemic blast cells.
    European journal of cancer, 1976, Volume: 12, Issue:4

    Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Daunorubicin; DNA, Neoplasm; Female; Humans; Leucine; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitotic Index; Neoplasm Proteins; Time Factors

1976
Low frequency of ras oncogene mutations in Philadelphia-positive acute leukemia and report of a novel mutation H61 Leu in a single case.
    Leukemia, 1992, Volume: 6, Issue:4

    Topics: Codon; Fusion Proteins, bcr-abl; Gene Expression Regulation, Neoplastic; Genes, ras; Glutamine; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Mutation; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transcriptional Activation

1992
[Bestatin-induced intravascular hemolysis in a patient with acute myelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:1

    Topics: Acute Disease; Adjuvants, Immunologic; Adolescent; Anemia, Hemolytic; Female; Hemolysis; Humans; Leucine; Leukemia, Myeloid, Acute

1990
Reduced cytotoxicity of the lysosomotropic detergent N-dodecylimidazole after differentiation of HL60 promyelocytes.
    Cancer research, 1989, Feb-01, Volume: 49, Issue:3

    Topics: Cathepsins; Cell Differentiation; Cell Line; Cell Survival; Granulocytes; Humans; Imidazoles; Leucine; Leukemia, Myeloid, Acute; Lysosomes; Macrophages

1989
Magnesium deprivation inhibits the expression of differentiation-related phenotypes in human promyelocytic leukemia HL-60 cells.
    Journal of cellular physiology, 1987, Volume: 131, Issue:1

    Topics: Aclarubicin; Amanitins; Bucladesine; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cycloheximide; Dimethyl Sulfoxide; Drug Interactions; Humans; Leucine; Leukemia, Myeloid, Acute; Magnesium Deficiency; Naphthacenes; Oncogenes; Peptide Chain Elongation, Translational; Phenotype; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin

1987
Relationship between membrane sterol composition and responsiveness to 12-O-tetradecanoylphorbol 13-acetate in HL-60 human promyelocytic leukaemia cell lines.
    The Biochemical journal, 1988, Mar-01, Volume: 250, Issue:2

    Topics: Acetates; Carbon Radioisotopes; Cell Line; Cholesterol; Humans; Lanosterol; Leucine; Leukemia, Myeloid, Acute; Lipid Metabolism; Pyruvates; Pyruvic Acid; Sterols; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured

1988
Effects of enzyme inhibitors in inhibiting the growth and inducing the differentiation of human promyelocytic leukemia cells, HL-60.
    The Journal of antibiotics, 1986, Volume: 39, Issue:5

    Topics: Anti-Bacterial Agents; Cell Differentiation; Cell Line; Enzyme Inhibitors; Glycine; Guanidines; Humans; Leucine; Leukemia, Myeloid, Acute; Oligopeptides; Peptides; Protease Inhibitors

1986
A short-term chemosensitivity test with different labeled precursors of DNA or protein synthesis: correlation with clinical response.
    Tumori, 1986, Aug-31, Volume: 72, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; DNA; Drug Administration Schedule; Drug Evaluation, Preclinical; Humans; Leucine; Leukemia, Myeloid, Acute; Protein Biosynthesis; Thioguanine; Thymidine

1986
Principia of cancer therapy. XI. Prostaglandin D2 induces redifferentiation of M1 leukemia cells in vitro irrespective of bestatin.
    The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku, 1985, Volume: 32, Issue:1-4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Leucine; Leukemia, Myeloid, Acute; Mice; Prostaglandin D2; Prostaglandins D

1985
[Behavior of aminopeptidase activity in human leukemic leukocytes].
    Folia haematologica (Leipzig, Germany : 1928), 1971, Volume: 96, Issue:3

    Topics: Acyltransferases; Adolescent; Adult; Aged; Aminopeptidases; Aspartic Acid; Child; Clinical Enzyme Tests; Eosinophils; Female; Glutamine; Glycine; Histocytochemistry; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Naphthols; Peptide Hydrolases

1971
A vitamin B12 binder with transcobalmin I characteristics synthesized and released by human granulocytes in vitro.
    British journal of haematology, 1974, Volume: 26, Issue:4

    Topics: Biological Assay; Blood Proteins; Chromatography; Cobalt Radioisotopes; Humans; In Vitro Techniques; Kinetics; Leucine; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Protein Binding; Tritium; Vitamin B 12

1974
Ferritin synthesis in normal and leukaemic leukocytes.
    Nature, 1974, Aug-16, Volume: 250, Issue:467

    Topics: Adult; Carbon Radioisotopes; Cell Division; Cells, Cultured; Centrifugation, Density Gradient; Ferritins; Humans; Iron; Leucine; Leukemia, Myeloid, Acute; Leukocytes; Spleen

1974
Autoradiographic studies of RNA metabolism in human leukaemic blast cells.
    Acta haematologica, 1971, Volume: 45, Issue:1

    Topics: Autoradiography; Bone Marrow; Bone Marrow Cells; Culture Techniques; Dactinomycin; DNA; Humans; Leucine; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; RNA; Tritium; Uridine

1971
RNA and protein synthesis in proliferating and non-proliferating blast cells of human acute leukaemia.
    Acta haematologica, 1971, Volume: 45, Issue:2

    Topics: Autoradiography; Blood Cells; Blood Proteins; Bone Marrow; Bone Marrow Cells; Cell Division; Culture Techniques; Dactinomycin; DNA; Humans; Leucine; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; RNA; Thymidine; Tritium; Uridine

1971
Studies of cellular proliferation in human leukemia. I. Estimation of growth rates of leukemic and normal hematopoietic cells in two adults with acute leukemia given single injections of tritiated thymidine.
    The Journal of clinical investigation, 1967, Volume: 46, Issue:4

    Topics: Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Division; DNA; Erythrocytes; Humans; Leucine; Leukemia, Myeloid, Acute; Leukocytes; Thymidine; Tritium; Uridine

1967
[Cytoautoradiographic research on cells of acute leukemia].
    Bollettino della Societa italiana di biologia sperimentale, 1968, Jan-31, Volume: 44, Issue:2

    Topics: Autoradiography; Blood Cells; Dactinomycin; DNA; Humans; Leucine; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Proteins; RNA; Thymidine; Uridine

1968
Degradation of RNA and changes in protein metabolism in human acute leukaemia cells treated with actinomycin D.
    Revue francaise d'etudes cliniques et biologiques, 1967, Volume: 12, Issue:10

    Topics: Dactinomycin; Humans; Leucine; Leukemia; Leukemia, Myeloid, Acute; Proteins; RNA; Time Factors; Tritium; Uridine

1967
Changes in protein metabolism in proliferating and non-proliferating human acute leukaemia cells treated with actinomycin-D.
    Experientia, 1969, Aug-15, Volume: 25, Issue:8

    Topics: Blood Proteins; Dactinomycin; Depression, Chemical; Humans; In Vitro Techniques; Leucine; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; RNA; Tritium

1969