leucine and Intellectual Disability

Topics: Animals; Autism Spectrum Disorder; Autoradiography; Brain; Carbon Radioisotopes; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 22; Disease Models, Animal; Intellectual Disability; Leucine; Mice; Mice, Knockout; Microfilament Proteins; Nerve Tissue Proteins; Protein Biosynthesis; Synaptosomes

Topics: Adolescent; Autophagy; Biomarkers; Child; Exome; Fibroblasts; Heredodegenerative Disorders, Nervous System; Humans; Intellectual Disability; Leucine; Male; Mechanistic Target of Rapamycin Complex 1; Mutation; Oligosaccharides; Phagosomes; Phenotype; Protein Serine-Threonine Kinases; Puerto Rico

Topics: Amino Acid Sequence; Animals; Histamine; Histamine N-Methyltransferase; Humans; Intellectual Disability; Leucine; Molecular Dynamics Simulation; Point Mutation; Protein Conformation; Protein Stability; Sequence Alignment

Topics: Biochemical Phenomena; Child; Humans; Infant; Intellectual Disability; Isoleucine; Leucine; Maple Syrup Urine Disease; Metabolic Diseases; Valine

Topics: Biochemical Phenomena; Child; Humans; Infant; Intellectual Disability; Leucine; Maple Syrup Urine Disease; Metabolic Diseases

Topics: Amino Acids; Brain; Glutamate Decarboxylase; Humans; Intellectual Disability; Ketosis; Leucine; Lyases; Maple Syrup Urine Disease; Metabolic Diseases; Phenylalanine; Phenylketonurias; Valine

Topics: Biochemical Phenomena; Humans; Intellectual Disability; Leucine; Maple Syrup Urine Disease; Valine

Topics: Epilepsy; Humans; Hypersensitivity; Hypoglycemia; Intellectual Disability; Leucine; Male

Topics: Acer; Child; Humans; Infant; Intellectual Disability; Leucine; Maple Syrup Urine Disease; Metabolic Diseases; Methionine

Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Chromatography, Gas; Fatty Acids; Female; Humans; Infant; Intellectual Disability; Isoleucine; Leucine; Male; Valine

Topics: Diet Therapy; Dietary Carbohydrates; Female; Humans; Hypoglycemia; Infant; Intellectual Disability; Leucine; Male

Topics: Amino Acid Metabolism, Inborn Errors; Asian People; Carbon Isotopes; Child, Preschool; Female; Fetal Diseases; Humans; Intellectual Disability; Isoleucine; Japan; Keto Acids; Leucine; Leukocytes; Methionine; Phenylalanine; Placenta; Pregnancy; Transaminases; Valine

Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Female; Humans; Intellectual Disability; Intelligence; Intelligence Tests; Least-Squares Analysis; Leucine; Male; Maple Syrup Urine Disease; Phenylketonurias

Topics: Amino Acid Metabolism, Inborn Errors; Carbon-Carbon Ligases; Carnitine; Diet, Protein-Restricted; Failure to Thrive; Female; Gliosis; Hemiplegia; Humans; Infant; Intellectual Disability; Leucine; Seizures

Topics: Adult; Exons; Family Health; Female; Gene Silencing; Guanine Nucleotide Exchange Factors; Humans; Intellectual Disability; Leucine; Male; Mutation; Mutation, Missense; Pedigree; Polymorphism, Single-Stranded Conformational; Proteins; src Homology Domains; Syndrome; X Chromosome

Topics: Adult; Cells, Cultured; Dwarfism; Female; Fucose; Galactosamine; Glycoproteins; Glycosaminoglycans; Hexosamines; Humans; Hyaluronic Acid; Intellectual Disability; Leucine; Lymphocytes; Male; Mucopolysaccharidoses; Proteinuria; Syndrome; Time Factors; Uronic Acids

Topics: Amino Acid Metabolism, Inborn Errors; Athetosis; Brain Diseases, Metabolic; Child; Chorea; Female; Humans; Intellectual Disability; Leucine; Male; Muscle Spasticity; Optic Atrophy

Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Child; Female; Fibroblasts; Humans; Hypoglycemia; Intellectual Disability; Isoleucine; Keto Acids; Ketosis; Leucine; Leukocytes; Valine

Topics: Blood Glucose; Diazoxide; Dietary Proteins; Drug Hypersensitivity; Epilepsy; Female; Humans; Hypertrichosis; Hypoglycemia; Infant; Infant, Newborn; Insulin; Intellectual Disability; Leucine; Male

Topics: Adult; Child; Child, Preschool; Female; Humans; Infant; Intellectual Disability; Intelligence; Intelligence Tests; Leucine; Male; Maple Syrup Urine Disease; Prognosis; Prospective Studies; Regression Analysis

Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Developmental Disabilities; Diet Therapy; Fatty Acids; Female; Glycine; Humans; Infant, Newborn; Intellectual Disability; Intelligence Tests; Leucine; Male; Odorants; Pedigree; Valerates

Topics: Autopsy; Child, Preschool; Developmental Disabilities; Fasting; Gliosis; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Intellectual Disability; Leucine; Male; Methylprednisolone; Occipital Lobe; Seizures; Temporal Lobe

Topics: Adrenocorticotropic Hormone; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Diabetes Mellitus; Diet Therapy; Electroencephalography; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Insulin Secretion; Intellectual Disability; Leucine; Liver Glycogen; Male; Neurologic Manifestations; Pancreatectomy; Prednisone; Pregnancy; Tolbutamide

Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Diazoxide; Glucose; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Leucine; Male; Pancreatectomy; Pancreatic Neoplasms; Prednisone; Tolbutamide

Topics: Acidosis; Adult; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Coma; Female; Humans; Intellectual Disability; Leucine; Male; Oxidoreductases; Pentanoic Acids

Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Brain Chemistry; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Intellectual Disability; Leucine; Methionine; Phenylalanine; Phenylketonurias; Rats; Tyrosine; Valine

Topics: Age Factors; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Arginine; Biological Transport, Active; Brain; Caproates; Carbon Radioisotopes; Depression, Chemical; Drug Interactions; Humans; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Rats; Rats, Inbred Strains; Stimulation, Chemical; Threonine

Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Dental Enamel Hypoplasia; Epilepsy; Ethylamines; Glutamine; Glycine; Histidine; Humans; Ichthyosis; Intellectual Disability; Isoleucine; Leucine; Lysine; Male; Muscle Spasticity; Retinal Degeneration; Serine; Syndrome; Valine

Topics: Amino Acids; Animals; Arginine; Blood-Brain Barrier; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Female; Histidine; Humans; Intellectual Disability; Isoleucine; Leucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Phenylketonurias; Rats; Threonine; Tryptophan; Tyrosine; Valine

Topics: Adolescent; Adult; Alanine; Amino Acids; Arginine; Carbohydrates; Child; Child, Preschool; Chromatography, Thin Layer; Cystine; Epilepsy; Female; Glutamates; Glutamine; Humans; Intellectual Disability; Intelligence Tests; Isoleucine; Leucine; Lysine; Male; Metabolism, Inborn Errors; Methionine; Middle Aged; Ornithine; Phenylalanine; Pneumoencephalography; Threonine; Valine

Topics: Catecholamines; Child; Child, Preschool; Cyanosis; Diazoxide; Diet Therapy; Fasting; Female; Fever; Humans; Hypoglycemia; Infant; Infant, Newborn; Insulin; Intellectual Disability; Isoleucine; Leucine; Male; Microcephaly; Pregnancy; Seizures; Valine

Topics: Acidosis; Blood Glucose; Child, Preschool; Diazoxide; Follow-Up Studies; Glucose; Glucose Tolerance Test; Humans; Hypertrichosis; Hypoglycemia; Infant; Infant, Newborn; Insulin; Intellectual Disability; Leucine; Stimulation, Chemical; Time Factors

Topics: Abnormalities, Multiple; Administration, Oral; Adolescent; Blood Glucose; Child; Child, Preschool; Female; Glucose Tolerance Test; Humans; Hypogonadism; Insulin; Insulin Secretion; Intellectual Disability; Islets of Langerhans; Laurence-Moon Syndrome; Leucine; Male; Obesity; Stimulation, Chemical

Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Chemical Phenomena; Chemistry; Child; Child, Preschool; Female; Homocystine; Humans; Hypoglycemia; Infant; Intellectual Disability; Leucine; Male; Maple Syrup Urine Disease; Methionine; Pyridoxine; Valine

Topics: Child, Preschool; Humans; Hyperkinesis; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Pedigree; Pyruvates; Valine

Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Humans; Injections, Intraperitoneal; Intellectual Disability; Leucine; Nerve Tissue Proteins; Phenylalanine; Rats

Topics: Amino Acids; Child Behavior Disorders; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Diet Therapy; Dietary Proteins; Female; Heterozygote; Humans; Infant; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Methionine; Motor Skills; Pedigree; Phenylketonurias; Tyrosine; Valine

Topics: Adolescent; Biological Transport; Carbon Isotopes; Child; Culture Techniques; Feces; Genes, Recessive; Hartnup Disease; Humans; Intellectual Disability; Intestinal Mucosa; Jejunum; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Tryptophan

Topics: Acetates; Age Factors; Animals; Brain; Carbon Isotopes; Female; Glycine; Humans; Intellectual Disability; Leucine; Male; Methionine; Myelin Sheath; Phenylalanine; Phenylketonurias; Protein Biosynthesis; Rats; Sulfur Isotopes

Topics: Blood Glucose; Child; Child, Preschool; Diet Therapy; Fasting; Female; Humans; Hypoglycemia; Infant; Insulin; Intellectual Disability; Leucine; Male

Topics: Amino Acid Metabolism, Inborn Errors; Diet; Dietary Proteins; Glycine; Humans; Infant; Infant, Newborn; Intellectual Disability; Isoleucine; Isomerases; Leucine; Male; Malonates; Valine; Vitamin B 12

Topics: Diet Therapy; Humans; Infant, Newborn; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Valine

Topics: Child, Preschool; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Isoleucine; Leucine; Maple Syrup Urine Disease; Prognosis; Time Factors; Valine

Topics: Child, Preschool; Female; Humans; Intellectual Disability; Isoleucine; Leucine; Male; Pyridines; Pyridoxine; Tryptophan; Valine

Topics: Autoanalysis; Diazoxide; Drug Hypersensitivity; Female; Glucose Tolerance Test; Hirsutism; Humans; Hypoglycemia; Infant; Insulin; Intellectual Disability; Leucine