leucine has been researched along with Insulinoma in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, L; Han, W; Jiang, X; Li, M; Zhang, X; Zhao, JJ | 1 |
| Cui, B; Gao, L; Guan, Q; Guo, H; Sun, N; Tian, L; Wang, L; Zhang, X; Zhao, J | 1 |
| Bonner, C; Byrne, MM; Farrelly, AM; Kilbride, SM; Prehn, JH | 1 |
| Hedeskov, CJ; Knudsen, P; Kofod, H; Lernmark, A | 1 |
| Chick, WL; Gishizky, ML; Gold, G; Grodsky, GM | 1 |
| Battezzati, A; Bianchi, E; Di Carlo, V; Luzi, L; Perseghin, G; Pozza, G; Terruzzi, I | 1 |
| Sandler, S; Welsh, N | 1 |
| Flatt, PR; McClenaghan, NH | 1 |
| Fiedorek, FT; Parkinson, D | 1 |
| Blachier, F; Leclercq-Meyer, V; Malaisse, WJ; Marchand, J; Sener, A | 1 |
| Schonbrunn, A; Sullivan, SJ | 2 |
12 other study(ies) available for leucine and Insulinoma
| Article | Year |
|---|---|
Chronic leucine exposure results in reduced but reversible glucose-stimulated insulin secretion in INS-1 cells.
Topics: Animals; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 2; Homeodomain Proteins; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Leucine; Rats; Trans-Activators; Tumor Cells, Cultured | 2014 |
AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin secretion under high leucine exposure in rat insulinoma beta-cells.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Death; Cell Line, Tumor; Enzyme Inhibitors; Glucokinase; Glucose Transporter Type 2; Homeodomain Proteins; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Leucine; Pancreatic Neoplasms; Rats; Ribonucleotides; Trans-Activators | 2009 |
Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Survival; Diabetes Mellitus, Type 1; Gene Expression Regulation; Genes, Dominant; Hepatocyte Nuclear Factor 1-alpha; Insulin-Secreting Cells; Insulinoma; Leucine; Mutation; Pancreatic Neoplasms; Protein Processing, Post-Translational; Rats; Real-Time Polymerase Chain Reaction; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2011 |
L-leucine methyl ester stimulates insulin secretion and islet glutamate dehydrogenase.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Glucagon; Glucose; Glutamate Dehydrogenase; Glutamine; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Leucine; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pancreatic Neoplasms; Rats | 1983 |
Contrasting patterns of insulin biosynthesis, compartmental storage, and secretion. Rat tumor versus islet cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Leucine; Male; Neoplasm Transplantation; Pancreatic Neoplasms; Proinsulin; Rats; Rats, Inbred Strains | 1984 |
Defective insulin action on protein and glucose metabolism during chronic hyperinsulinemia in subjects with benign insulinoma.
Topics: Adult; Blood Glucose; Carbon Radioisotopes; Chronic Disease; Glucose; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Insulinoma; Keto Acids; Leucine; Liver; Middle Aged; Pancreatic Neoplasms; Proteins; Radioisotope Dilution Technique; Reference Values; Tritium | 1995 |
Interleukin-10 stimulates rat pancreatic islets in vitro, but fails to protect against interleukin-1.
Topics: Animals; Cells, Cultured; DNA; Drug Interactions; Glucose; Humans; Insulin; Insulin Secretion; Insulinoma; Interleukin-1; Interleukin-10; Islets of Langerhans; Kinetics; Leucine; Male; Pancreatic Neoplasms; Proinsulin; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tritium; Tumor Cells, Cultured | 1993 |
Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion.
Topics: Animals; Arginine; Butyrates; Calcium; Calcium Channel Blockers; Calcium Channels; Coumaric Acids; Diazoxide; Glucose; Insulin; Insulin Secretion; Insulinoma; Ion Channel Gating; Ion Transport; Islets of Langerhans; Isoleucine; Keto Acids; Leucine; Membrane Potentials; Membrane Proteins; Mitochondria; Pancreatic Neoplasms; Phenylpyruvic Acids; Potassium Channels; Secretory Rate; Sodium Azide; Sodium Cyanide; Tumor Cells, Cultured; Valine; Verapamil | 2000 |
Carboxypeptidase H processing and secretion in rat clonal beta-cell lines.
Topics: Animals; Carboxypeptidase H; Carboxypeptidases; Cell Membrane; Clone Cells; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Insulin; Insulin Secretion; Insulinoma; Kinetics; Leucine; Pancreatic Neoplasms; Protein Processing, Post-Translational; Rats | 1992 |
Effects of L-leucine, its 2-keto acid metabolite and its non-metabolized analogue on rat tumoral islet cell function.
Topics: Adenine Nucleotides; Adenoma, Islet Cell; Amino Acids; Amino Acids, Cyclic; Animals; Calcium Radioisotopes; Cell Line; Insulin; Insulinoma; Keto Acids; Leucine; Phosphatidylinositols; Phosphorus Radioisotopes; Rats; Rubidium Radioisotopes; Time Factors; Tumor Cells, Cultured | 1988 |
Characterization of somatostatin receptors which mediate inhibition of insulin secretion in RINm5F insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Binding, Competitive; Cell Line; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Kinetics; Leucine; Pancreatic Neoplasms; Rats; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin | 1987 |
Distribution of somatostatin receptors in RINm5F insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Cell Fractionation; Cell Membrane; Colforsin; Cytoplasmic Granules; Cytosol; Glucagon; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Iodine Radioisotopes; Kinetics; Leucine; Microsomes; Pancreatic Neoplasms; Rats; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin; Tumor Cells, Cultured | 1988 |