leucine and Insulinoma

leucine has been researched along with Insulinoma in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, L; Han, W; Jiang, X; Li, M; Zhang, X; Zhao, JJ1
Cui, B; Gao, L; Guan, Q; Guo, H; Sun, N; Tian, L; Wang, L; Zhang, X; Zhao, J1
Bonner, C; Byrne, MM; Farrelly, AM; Kilbride, SM; Prehn, JH1
Hedeskov, CJ; Knudsen, P; Kofod, H; Lernmark, A1
Chick, WL; Gishizky, ML; Gold, G; Grodsky, GM1
Battezzati, A; Bianchi, E; Di Carlo, V; Luzi, L; Perseghin, G; Pozza, G; Terruzzi, I1
Sandler, S; Welsh, N1
Flatt, PR; McClenaghan, NH1
Fiedorek, FT; Parkinson, D1
Blachier, F; Leclercq-Meyer, V; Malaisse, WJ; Marchand, J; Sener, A1
Schonbrunn, A; Sullivan, SJ2

Other Studies

12 other study(ies) available for leucine and Insulinoma

ArticleYear
Chronic leucine exposure results in reduced but reversible glucose-stimulated insulin secretion in INS-1 cells.
    Molecular medicine reports, 2014, Volume: 9, Issue:6

    Topics: Animals; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 2; Homeodomain Proteins; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Leucine; Rats; Trans-Activators; Tumor Cells, Cultured

2014
AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin secretion under high leucine exposure in rat insulinoma beta-cells.
    Journal of cellular and molecular medicine, 2009, Volume: 13, Issue:4

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Death; Cell Line, Tumor; Enzyme Inhibitors; Glucokinase; Glucose Transporter Type 2; Homeodomain Proteins; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Leucine; Pancreatic Neoplasms; Rats; Ribonucleotides; Trans-Activators

2009
Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:11

    Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Survival; Diabetes Mellitus, Type 1; Gene Expression Regulation; Genes, Dominant; Hepatocyte Nuclear Factor 1-alpha; Insulin-Secreting Cells; Insulinoma; Leucine; Mutation; Pancreatic Neoplasms; Protein Processing, Post-Translational; Rats; Real-Time Polymerase Chain Reaction; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2011
L-leucine methyl ester stimulates insulin secretion and islet glutamate dehydrogenase.
    The American journal of physiology, 1983, Volume: 245, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Glucagon; Glucose; Glutamate Dehydrogenase; Glutamine; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Leucine; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pancreatic Neoplasms; Rats

1983
Contrasting patterns of insulin biosynthesis, compartmental storage, and secretion. Rat tumor versus islet cells.
    Diabetes, 1984, Volume: 33, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Leucine; Male; Neoplasm Transplantation; Pancreatic Neoplasms; Proinsulin; Rats; Rats, Inbred Strains

1984
Defective insulin action on protein and glucose metabolism during chronic hyperinsulinemia in subjects with benign insulinoma.
    Diabetes, 1995, Volume: 44, Issue:7

    Topics: Adult; Blood Glucose; Carbon Radioisotopes; Chronic Disease; Glucose; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Insulinoma; Keto Acids; Leucine; Liver; Middle Aged; Pancreatic Neoplasms; Proteins; Radioisotope Dilution Technique; Reference Values; Tritium

1995
Interleukin-10 stimulates rat pancreatic islets in vitro, but fails to protect against interleukin-1.
    Biochemical and biophysical research communications, 1993, Sep-15, Volume: 195, Issue:2

    Topics: Animals; Cells, Cultured; DNA; Drug Interactions; Glucose; Humans; Insulin; Insulin Secretion; Insulinoma; Interleukin-1; Interleukin-10; Islets of Langerhans; Kinetics; Leucine; Male; Pancreatic Neoplasms; Proinsulin; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tritium; Tumor Cells, Cultured

1993
Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion.
    Pancreas, 2000, Volume: 20, Issue:1

    Topics: Animals; Arginine; Butyrates; Calcium; Calcium Channel Blockers; Calcium Channels; Coumaric Acids; Diazoxide; Glucose; Insulin; Insulin Secretion; Insulinoma; Ion Channel Gating; Ion Transport; Islets of Langerhans; Isoleucine; Keto Acids; Leucine; Membrane Potentials; Membrane Proteins; Mitochondria; Pancreatic Neoplasms; Phenylpyruvic Acids; Potassium Channels; Secretory Rate; Sodium Azide; Sodium Cyanide; Tumor Cells, Cultured; Valine; Verapamil

2000
Carboxypeptidase H processing and secretion in rat clonal beta-cell lines.
    Endocrinology, 1992, Volume: 131, Issue:3

    Topics: Animals; Carboxypeptidase H; Carboxypeptidases; Cell Membrane; Clone Cells; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Insulin; Insulin Secretion; Insulinoma; Kinetics; Leucine; Pancreatic Neoplasms; Protein Processing, Post-Translational; Rats

1992
Effects of L-leucine, its 2-keto acid metabolite and its non-metabolized analogue on rat tumoral islet cell function.
    Journal of molecular endocrinology, 1988, Volume: 1, Issue:1

    Topics: Adenine Nucleotides; Adenoma, Islet Cell; Amino Acids; Amino Acids, Cyclic; Animals; Calcium Radioisotopes; Cell Line; Insulin; Insulinoma; Keto Acids; Leucine; Phosphatidylinositols; Phosphorus Radioisotopes; Rats; Rubidium Radioisotopes; Time Factors; Tumor Cells, Cultured

1988
Characterization of somatostatin receptors which mediate inhibition of insulin secretion in RINm5F insulinoma cells.
    Endocrinology, 1987, Volume: 121, Issue:2

    Topics: Adenoma, Islet Cell; Animals; Binding, Competitive; Cell Line; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Kinetics; Leucine; Pancreatic Neoplasms; Rats; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin

1987
Distribution of somatostatin receptors in RINm5F insulinoma cells.
    Endocrinology, 1988, Volume: 122, Issue:3

    Topics: Adenoma, Islet Cell; Animals; Cell Fractionation; Cell Membrane; Colforsin; Cytoplasmic Granules; Cytosol; Glucagon; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Iodine Radioisotopes; Kinetics; Leucine; Microsomes; Pancreatic Neoplasms; Rats; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin; Tumor Cells, Cultured

1988