leucine and Idiopathic Parkinson Disease

leucine has been researched along with Idiopathic Parkinson Disease in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (4.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (14.00)	29.6817
2010's	15 (30.00)	24.3611
2020's	26 (52.00)	2.80

Authors

Authors	Studies
Bendjebara, M; Damak, M; Farhat, N; Gargouri, A; Gharbi, A; Gouider, R; Kacem, I; Mhiri, C; Nasri, A; Sakka, S; Souissi, A; Zidi, S	1
Bloodgood, DW; Chen, P; Ding, JB; Huang, G; Kaganovsky, K; Kang, J; Kim, JI; Shahapal, A; Shen, J	1
Bryant, N; Bukhari, SA; Chartier-Harlin, MC; Chittoor-Vinod, VG; Cookson, MR; Fdez, E; Fernández, B; Hilfiker, S; Kelly, K; Kluss, JH; Lara Ordóñez, AJ; Montine, TJ; Moore, DJ; Nguyen, APT; Nichols, RJ; Smith, N; West, AB; Wilson, MA	1
Al-Nusaif, M; Cheng, C; Le, W; Li, S; Liu, X; Wang, Y; Yu, H	1
Greggio, E; Kluss, JH; Lewis, PA	1
Chen, J; Chen, S; Luo, Q; Ma, J; Pan, J; Tang, H; Wang, P	1
Alexander, A; Dolga, AM; Galuh, S; Kortholt, A; Oun, A; Sabogal-Guaqueta, AM	1
Kim, YE; Kim, YJ; Lai, TT; Lee, YK; Ma, HI; Nguyen, HD; Nguyen, LTN; Nguyen, TT	1
Chien, CT; Dewadas, HD; Foo, CN; Lim, YM; Lin, YE; Ravinther, AI; Tong, SR	1
Fujino, Y; Kasai, T; Kitani-Morii, F; Menjo, K; Mizuno, T; Ohmichi, T; Shinomoto, M	1
Amin, RP; Besteman, EG; Ciaccio, PJ; Gatto, NT; Glaab, WE; Gu, YZ; Kuruvilla, S; Lebron, J; Miller, G; Reynolds, SJ; Sistare, FD; Smith, R; Vlasakova, K; Wollenberg, G	1
Groeneveld, GJ; Heuberger, JAAC; Huntwork-Rodriguez, S; Pereira, DR; Thijssen, E; Troyer, MD; Vissers, MFJM	1
Kortholt, A; Zhang, X	1
Herbst, S; Lewis, PA; Zhu, C	1
Albus, A; Burg-Roderfeld, M; Dodel, R; Kronimus, Y; Ross, JA; van der Wurp, H; Willbold, D; Ziehm, T	1
Cao, R; Chen, C; Shan, L; Sun, H; Sun, L; Wen, J; Wu, C; Xi, M; Yuan, L; Zhang, C; Zhao, W	1
A, A; Ahmed, SS; K, S; Kumar, S; Kuriakose, B; Murugesan, R; Rs, AH; S, V; V, R	1
Alcalay, RN; Bressman, S; Brumm, MC; Caspell-Garcia, C; Chahine, LM; Coffey, CS; Foroud, T; Galasko, D; Hutten, S; Kieburtz, K; Marek, K; Mollenhauer, B; Nudelman, K; Poston, K; Reimer, A; Seibyl, J; Shaw, LM; Siderowf, A; Simuni, T; Singleton, A; Tanner, CM; Toga, AW; Tosun-Turgut, D; Trojanowski, JQ; Uribe, L; Weintraub, D	1
Datta, I; Jagtap, S; Pal, P; Potdar, C; Yadav, R	1
Chen, J; Ge, YL; Gu, CC; Jin, H; Li, K; Liu, CF; Mao, CJ; Wang, F; Yang, YP; Zhang, JR; Zhang, YC	1
Bonet-Ponce PhD, L; Cookson, MR	1
Alcalay, RN; Baptista, MAS; Hutten, SJ; Joshi, N; Kang, MS; Kang, UJ; Kopil, K; Levers, N; Liong, C; Melachroinou, K; Narayan, S; Padmanabhan, S; Rideout, HJ; Stefanis, L	1
Das, P; Halder, T; Joshi, D; Pandey, S; Raj, J; Sharma, V; Singh, RK; Verma, SP	1
Azeggagh, S; Berwick, DC	1
Beylina, A; Cookson, MR; Langston, RG; Reed, X; Rosen, D	1
Ganesan, S; Heijjer, CN; Hwang, IY; Karlsson, MCI; Kehrl, JH; Nabar, NR; Shi, CS	1
de Michele, G; de Rosa, A; Dubbioso, R; Esposito, M; Iodice, R; Manganelli, F; Peluso, S; Santoro, L	1
Aarabi, MH; Ghazi Sherbaf, F; Same, K	1
Roosen, DA; Singleton, AB	1
Barichella, M; Bolliri, C; Caroli, D; Caronni, S; Cassani, E; Cereda, E; Ferrazzoli, D; Ferri, V; Frazzitta, G; Iorio, L; Maggio, M; Maras, A; Masiero, I; Ortelli, P; Pezzoli, G; Pinelli, G; Riboldazzi, G	1
Sun, HM; Wang, ZZ; Zhang, Y	1
Baekelandt, V; Bandopadhyay, R; Beilina, A; Belluzzi, E; Bubacco, L; Cirnaru, MD; Civiero, L; Cookson, MR; Greggio, E; Hondhamuni, G; Lewis, PA; Lobbestael, E; Piccoli, G; Reyniers, L; Rodella, U; Russo, I; Taymans, JM; Van den Haute, C	1
de Boer, AH; Frijlink, HW; Grasmeijer, F; Hagedoorn, P; Luinstra, M; Moes, JR	1
Dinelle, K; Ding, YS; Farrer, M; McKenzie, J; Schaffer, P; Sossi, V; Stoessl, AJ; Tsui, JK; Vafai, N; Wile, DJ	1
An, R; Chen, Y; Tian, S; Xu, Y; Yang, X; Zhao, Q; Zheng, J	1
Cookson, MR	1
Cheng, L; Li, JY; Li, NN; Lu, ZJ; Peng, R; Sun, XY; Tan, EK; Wang, L; Zhang, JH	1
Balck, A; Klein, C	1
Borompokas, N; Bronstein, JM; Hadjigeorgiou, GM; Kanavouras, K; Latsoudis, H; Mastorodemos, V; Papapetropoulos, S; Plaitakis, A; Ritz, B; Skoula, I; Spanaki, C; Xiromerisiou, G; Zaganas, I	1
Guo, JF; Pan, Q; Sun, QY; Tang, BS; Wang, L; Xia, K; Yao, LY; Yu, RH; Zuo, X	1
Augustin, J; Ayrignac, X; Campion, D; Clanet, M; Coutant, S; Defebvre, L; Frébourg, T; Guyant-Maréchal, L; Hannequin, D; Krystkowiak, P; Labauge, P; Le Ber, I; Lefaucheur, R; Legallic, S; Maltête, D; Martinaud, O; Nicolas, G; Pariente, J; Pottier, C; Rousseau, S; Rovelet-Lecrux, A; Vaschalde, Y	1
Anvret, M; Buervenich, S; Carmine, A; Olson, L; Sydow, O	1
Clarimon, J; Eerola, J; Hellström, O; Singleton, A; Tienari, PJ	1
Aasly, JO; Farrer, MJ; Pielsticker, L; Ross, OA; Toft, M	1
Chen, S; Deng, X; Ding, X; Dong, H; Li, W; Li, X; Ma, G; Wu, T; Yao, J; Zeng, Y; Zhang, X	1
Annesi, F; Annesi, G; Carrideo, S; Cirò Candiano, IC; Civitelli, D; Condino, F; De Marco, EV; Messina, D; Morelli, M; Nicoletti, G; Novellino, F; Provenzano, G; Quattrone, A; Rocca, FE; Tarantino, P	1
Bird, TD; Griffith, A; Leis, BC; Leverenz, JB; Mata, IF; Roberts, JW; Samii, A; Schellenberg, GD; Schneer, SH; Sidransky, E; Tsuang, D; Zabetian, CP	1
Bock, H; Hilbig, A; Jardim, LB; Michelin-Tirelli, K; Rieder, CR; Saraiva-Pereira, ML; Socal, MP	1
Chase, TN; Lipton, MA; Morris, CE; Woods, AC	1
Barbeau, A; Kastin, AJ	1

Reviews

10 review(s) available for leucine and Idiopathic Parkinson Disease

Article	Year
Leucine-rich repeat kinase 2 (LRRK2): an update on the potential therapeutic target for Parkinson's disease. Expert opinion on therapeutic targets, 2022, Volume: 26, Issue:6 Topics: Animals; Drug Design; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Parkinson Disease	2022
The multifaceted role of LRRK2 in Parkinson's disease: From human iPSC to organoids. Neurobiology of disease, 2022, 10-15, Volume: 173 Topics: Aged; Humans; Induced Pluripotent Stem Cells; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Neurodegenerative Diseases; Organoids; Parkinson Disease	2022
Role of NLRP3 Inflammasome in Parkinson's Disease and Therapeutic Considerations. Journal of Parkinson's disease, 2022, Volume: 12, Issue:7 Topics: alpha-Synuclein; Cytokines; Humans; Inflammasomes; Inflammation; Leucine; Neurodegenerative Diseases; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides; Parkinson Disease	2022
Molecular Pathways Involved in LRRK2-Linked Parkinson's Disease: A Systematic Review. International journal of molecular sciences, 2022, Oct-03, Volume: 23, Issue:19 Topics: Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Neurodegenerative Diseases; Parkinson Disease	2022
LRRK2 Structure-Based Activation Mechanism and Pathogenesis. Biomolecules, 2023, 03-28, Volume: 13, Issue:4 Topics: GTP Phosphohydrolases; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases	2023
Recent advances in targeting leucine-rich repeat kinase 2 as a potential strategy for the treatment of Parkinson's disease. Bioorganic chemistry, 2023, Volume: 141 Topics: Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Neurodegenerative Diseases; Parkinson Disease; Protein Serine-Threonine Kinases	2023
Association of leucine-rich repeat kinase 2 gene rs10878307 polymorphism and Parkinson's disease risk in South India-A meta-analysis and molecular dynamics simulation. Journal of biomolecular structure & dynamics, 2020, Volume: 38, Issue:18 Topics: Humans; India; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Molecular Dynamics Simulation; Parkinson Disease; Protein Serine-Threonine Kinases	2020
The development of inhibitors of leucine-rich repeat kinase 2 (LRRK2) as a therapeutic strategy for Parkinson's disease: the current state of play. British journal of pharmacology, 2022, Volume: 179, Issue:8 Topics: Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease	2022
A meta-analysis of the relationship of the Parkin p.Val380Leu polymorphism to Parkinson's disease. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2013, Volume: 162B, Issue:3 Topics: Adult; Age of Onset; Aged; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Heterozygote; Homozygote; Humans; Leucine; Male; Middle Aged; Odds Ratio; Parkinson Disease; Polymorphism, Genetic; Ubiquitin-Protein Ligases; Valine	2013
Mutational scanning of the CHCHD2 gene in Han Chinese patients with Parkinson's disease and meta-analysis of the literature. Parkinsonism & related disorders, 2016, Volume: 29 Topics: Adult; Aged; Asian People; DNA Mutational Analysis; DNA-Binding Proteins; Genetic Association Studies; Genotype; Humans; Leucine; Middle Aged; Mitochondrial Proteins; Mutation; Parkinson Disease; Proline; Transcription Factors	2016

Trials

1 trial(s) available for leucine and Idiopathic Parkinson Disease

Article	Year
Muscle-targeted nutritional support for rehabilitation in patients with parkinsonian syndrome. Neurology, 2019, 07-30, Volume: 93, Issue:5 Topics: Aged; Amino Acids, Essential; Body Weight; Cholecalciferol; Dietary Proteins; Dietary Supplements; Female; Food, Fortified; Humans; Leucine; Male; Middle Aged; Muscle, Skeletal; Nutritional Support; Parkinson Disease; Parkinsonian Disorders; Physical Functional Performance; Treatment Outcome; Vitamins; Walk Test; Walking Speed; Whey Proteins	2019

Article

Year

Muscle-targeted nutritional support for rehabilitation in patients with parkinsonian syndrome.

Neurology, 2019, 07-30, Volume: 93, Issue:5

Topics: Aged; Amino Acids, Essential; Body Weight; Cholecalciferol; Dietary Proteins; Dietary Supplements; Female; Food, Fortified; Humans; Leucine; Male; Middle Aged; Muscle, Skeletal; Nutritional Support; Parkinson Disease; Parkinsonian Disorders; Physical Functional Performance; Treatment Outcome; Vitamins; Walk Test; Walking Speed; Whey Proteins

2019

Other Studies

39 other study(ies) available for leucine and Idiopathic Parkinson Disease

Article	Year
Heart rate variability and sympathetic skin response for the assessment of autonomic dysfunction in leucine-rich repeat kinase 2 associated Parkinson's disease. Neurophysiologie clinique = Clinical neurophysiology, 2022, Volume: 52, Issue:1 Topics: Cross-Sectional Studies; Female; Heart Rate; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mutation; Parkinson Disease; Primary Dysautonomias	2022
Motor Impairments and Dopaminergic Defects Caused by Loss of Leucine-Rich Repeat Kinase Function in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022, 06-08, Volume: 42, Issue:23 Topics: Animals; Dopamine; Dopaminergic Neurons; Female; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mice; Mice, Knockout; Motor Disorders; Parkinson Disease	2022
Evaluation of Current Methods to Detect Cellular Leucine-Rich Repeat Kinase 2 (LRRK2) Kinase Activity. Journal of Parkinson's disease, 2022, Volume: 12, Issue:5 Topics: Animals; Fibroblasts; HEK293 Cells; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mutation; Parkinson Disease; Phosphorylation; rab GTP-Binding Proteins; Rats; Reproducibility of Results	2022
Altered Motor Performance, Sleep EEG, and Parkinson's Disease Pathology Induced by Chronic Sleep Deprivation in Lrrk2 Neuroscience bulletin, 2022, Volume: 38, Issue:10 Topics: alpha-Synuclein; Animals; Electroencephalography; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Transgenic; Mutation; Parkinson Disease; Sleep Deprivation	2022
A 10-Year Community-Based Study of Leucine-Rich Repeat Kinase 2 G2385R Carriers' Conversion to Parkinson's Disease. Movement disorders : official journal of the Movement Disorder Society, 2022, Volume: 37, Issue:8 Topics: China; Heterozygote; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease	2022
Serum leucine-rich α2 glycoprotein as a potential biomarker for systemic inflammation in Parkinson's disease. PloS one, 2023, Volume: 18, Issue:2 Topics: Animals; Biomarkers; Dementia; Glycoproteins; Inflammation; Leucine; Parkinson Disease	2023
Early-Onset albuminuria and Associated Renal Pathology in Leucine-Rich Repeat Kinase 2 Knockout Rats. Toxicologic pathology, 2023, Volume: 51, Issue:1-2 Topics: Albuminuria; Animals; Biomarkers; Female; Kidney; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mice; Mice, Knockout; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Rats; Rats, Long-Evans	2023
A leucine-rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls. Clinical and translational science, 2023, Volume: 16, Issue:8 Topics: Biomarkers; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Leukocytes, Mononuclear; Mutation; Parkinson Disease	2023
Leucine-rich repeat kinase 2 at a glance. Journal of cell science, 2023, 09-01, Volume: 136, Issue:17 Topics: Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease	2023
The Avidity of Autoreactive Alpha-Synuclein Antibodies in Leucine-Rich Repeat Kinase 2 Mutation Carriers Is Not Altered Compared to Healthy Controls or Patients with Parkinson's Disease. Biomolecules, 2023, 08-25, Volume: 13, Issue:9 Topics: alpha-Synuclein; Autoantibodies; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease	2023
Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study. Movement disorders : official journal of the Movement Disorder Society, 2020, Volume: 35, Issue:5 Topics: Cross-Sectional Studies; Disabled Persons; Dopamine Plasma Membrane Transport Proteins; Glucosylceramidase; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Longitudinal Studies; Motor Disorders; Mutation; Parkinson Disease	2020
Generation of induced pluripotent stem cells (NIMHi001-A) from a Parkinson's disease patient of East Indian ethnicity carrying LRRK2 I1371V variant. Stem cell research, 2020, Volume: 44 Topics: Ethnicity; Humans; Induced Pluripotent Stem Cells; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Leukocytes, Mononuclear; Mutation; Parkinson Disease	2020
Substantia nigra hyperechogenicity in Parkinson disease patients with leucine-rich repeat kinase 2 variants in the Chinese Han population. Chinese medical journal, 2020, 06-20, Volume: 133, Issue:12 Topics: China; Humans; Leucine; Parkinson Disease; Substantia Nigra; Ultrasonography, Doppler, Transcranial	2020
Can Leucine-Rich Repeat Kinase 2 Inhibition Benefit GBA-Parkinson's Disease? Movement disorders : official journal of the Movement Disorder Society, 2020, Volume: 35, Issue:5 Topics: Glucosylceramidase; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease	2020
Elevated In Vitro Kinase Activity in Peripheral Blood Mononuclear Cells of Leucine-Rich Repeat Kinase 2 G2019S Carriers: A Novel Enzyme-Linked Immunosorbent Assay-Based Method. Movement disorders : official journal of the Movement Disorder Society, 2020, Volume: 35, Issue:11 Topics: Enzyme-Linked Immunosorbent Assay; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Leukocytes, Mononuclear; Mutation; Parkinson Disease	2020
Identification & characterization of leucine-rich repeat kinase 2 & parkin RBR E3 ubiquitin protein ligase variants in patients with Parkinson's disease. The Indian journal of medical research, 2020, Volume: 152, Issue:5 Topics: Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease; Ubiquitin-Protein Ligases	2020
Generation of fourteen isogenic cell lines for Parkinson's disease-associated leucine-rich repeat kinase (LRRK2). Stem cell research, 2021, Volume: 53 Topics: Cell Line; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases	2021
LRRK2 is required for CD38-mediated NAADP-Ca Autophagy, 2022, Volume: 18, Issue:1 Topics: Adenosine Diphosphate Ribose; Antibodies, Monoclonal; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Calcium; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Lipopolysaccharides; Lysosomes; NADP; Parkinson Disease; Transcription Factors	2022
Does motor cortex plasticity depend on the type of mutation in the leucine-rich repeat kinase 2 gene? Movement disorders : official journal of the Movement Disorder Society, 2017, Volume: 32, Issue:6 Topics: Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Motor Cortex; Mutation; Parkinson Disease	2017
New link between Parkinson's and Alzheimer's: Research uncovers the role of mutant leucine rich repeat kinase 2 and amyloid precursor protein. Movement disorders : official journal of the Movement Disorder Society, 2017, Volume: 32, Issue:10 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Parkinson Disease; Phosphorylation	2017
Leucine rich repeat kinase knockout (LRRK KO) mouse model: Linking pathological hallmarks of inherited and sporadic Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2018, Volume: 33, Issue:1 Topics: Animals; Autophagy; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Knockout; Parkinson Disease	2018
Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain. Journal of neurochemistry, 2015, Volume: 135, Issue:6 Topics: Actin Cytoskeleton; Animals; Brain; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mammals; Mice; Mutation; Neurites; p21-Activated Kinases; Parkinson Disease; Protein Serine-Threonine Kinases	2015
A levodopa dry powder inhaler for the treatment of Parkinson's disease patients in off periods. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2015, Volume: 97, Issue:Pt A Topics: Administration, Inhalation; Aerosols; Antiparkinson Agents; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Dry Powder Inhalers; Excipients; Humans; Leucine; Levodopa; Parkinson Disease; Reproducibility of Results; Tissue Distribution	2015
A scan without evidence is not evidence of absence: Scans without evidence of dopaminergic deficit in a symptomatic leucine-rich repeat kinase 2 mutation carrier. Movement disorders : official journal of the Movement Disorder Society, 2016, Volume: 31, Issue:3 Topics: Brain; Dopamine; Female; Heterozygote; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Middle Aged; Mutation; Parkinson Disease; Positron-Emission Tomography; Radionuclide Imaging	2016
Structure, function, and leucine-rich repeat kinase 2: On the importance of reproducibility in understanding Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America, 2016, 07-26, Volume: 113, Issue:30 Topics: Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Reproducibility of Results	2016
Genetic analysis of CHCHD2 gene in Chinese Parkinson's disease. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2016, Volume: 171, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Alleles; Asian People; China; DNA-Binding Proteins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Leucine; Male; Middle Aged; Mitochondrial Proteins; Mutation; Parkinson Disease; Proline; Risk Factors; Transcription Factors	2016
Reduced penetrance of Leucine-rich repeat kinase 2 mutations: Discovering genetic factors of endogenous disease protection. Movement disorders : official journal of the Movement Disorder Society, 2017, Volume: 32, Issue:4 Topics: Humans; Leucine; Mutation; Parkinson Disease; Penetrance; Protein Serine-Threonine Kinases	2017
Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset. European journal of human genetics : EJHG, 2010, Volume: 18, Issue:3 Topics: Adenosine Diphosphate; Age of Onset; Aged; Biocatalysis; California; Cohort Studies; Demography; Diethylstilbestrol; Female; Glutamate Dehydrogenase; Greece; Guanosine Triphosphate; Humans; Leucine; Male; Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Recombinant Proteins	2010
Glucocerebrosidase gene L444P mutation is a risk factor for Parkinson's disease in Chinese population. Movement disorders : official journal of the Movement Disorder Society, 2010, Jun-15, Volume: 25, Issue:8 Topics: Adult; Asian People; Case-Control Studies; Chi-Square Distribution; DNA Mutational Analysis; Female; Glucosylceramidase; Humans; Leucine; Male; Meta-Analysis as Topic; Middle Aged; Mutation; Parkinson Disease; Proline	2010
Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification. Neurology, 2013, Jan-08, Volume: 80, Issue:2 Topics: Adult; Aged; Amino Acid Substitution; Arginine; Basal Ganglia Diseases; Calcinosis; Child; Databases, Genetic; Exome; Female; Humans; Leucine; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neurologic Examination; Parkinson Disease; Pedigree; Polymerase Chain Reaction; Proline; Receptor, Platelet-Derived Growth Factor beta; Tomography, X-Ray Computed; Tryptophan	2013
Further evidence for an association of the paraoxonase 1 (PON1) Met-54 allele with Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2002, Volume: 17, Issue:4 Topics: Adult; Aged; Alleles; Amino Acid Substitution; Aryldialkylphosphatase; Esterases; Female; Gene Frequency; Genotype; Humans; Leucine; Lipid Peroxidation; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Reference Values; Sweden	2002
Paraoxonase 1 (PON1) gene polymorphisms and Parkinson's disease in a Finnish population. Neuroscience letters, 2004, Sep-02, Volume: 367, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Arginine; Aryldialkylphosphatase; Case-Control Studies; DNA Mutational Analysis; Female; Finland; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic	2004
Glucocerebrosidase gene mutations and Parkinson disease in the Norwegian population. Neurology, 2006, Feb-14, Volume: 66, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Asparagine; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Glucosylceramidase; Heterozygote; Humans; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine	2006
A novel P755L mutation in LRRK2 gene associated with Parkinson's disease. Neuroreport, 2006, Dec-18, Volume: 17, Issue:18 Topics: Adult; Aged; Aged, 80 and over; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2006
Glucocerebrosidase gene mutations are associated with Parkinson's disease in southern Italy. Movement disorders : official journal of the Movement Disorder Society, 2008, Feb-15, Volume: 23, Issue:3 Topics: Aged; Asparagine; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucosylceramidase; Humans; Italy; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine	2008
Glucocerebrosidase gene mutations: a risk factor for Lewy body disorders. Archives of neurology, 2008, Volume: 65, Issue:3 Topics: Aged; Asparagine; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucosylceramidase; Humans; Leucine; Lewy Body Disease; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Risk Factors; Serine	2008
Parkinson's disease and the heterozygous state for glucocerebrosidase mutations among Brazilians. Parkinsonism & related disorders, 2009, Volume: 15, Issue:1 Topics: Adult; Asparagine; Brazil; Female; Glucosylceramidase; Heterozygote; Humans; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine	2009
Hypothalamic releasing factors and Parkinson disease. Archives of neurology, 1974, Volume: 31, Issue:1 Topics: Antiparkinson Agents; Depression, Chemical; Dihydroxyphenylalanine; Drug Therapy, Combination; Glycine; Humans; Leucine; Melanocyte-Stimulating Hormones; Oligopeptides; Parkinson Disease; Pituitary Hormone-Releasing Hormones; Proline; Thyrotropin-Releasing Hormone	1974
Preliminary clinical studies with L-prolyl-L-leucyl-glycine amide in Parkinson's disease. Canadian Medical Association journal, 1972, Dec-09, Volume: 107, Issue:11 Topics: Administration, Oral; Aged; Amides; Antiparkinson Agents; Dihydroxyphenylalanine; Female; Glycine; Humans; Injections, Intravenous; Leucine; Male; Middle Aged; Movement Disorders; Parkinson Disease; Peptides; Proline	1972