leucine has been researched along with Granulocytic Leukemia, Chronic in 16 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (12.50) | 18.7374 |
1990's | 7 (43.75) | 18.2507 |
2000's | 5 (31.25) | 29.6817 |
2010's | 2 (12.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Divoka, M; Divoky, V; Faber, E; Indrak, K; Jarosova, M; Mojzikova, R; Plachy, R; Rozmanova, S; Stastny, M | 1 |
Bassan, R; Bussini, A; Castagnetti, F; Gnani, A; Intermesoli, T; Rosti, G; Soverini, S; Spinelli, O | 1 |
Abe, F; Fujisaki, T; Gondo, H; Niho, Y; Ohhinata, A; Okamura, T; Otsuka, T | 1 |
AGOSTONI, A; DIOGUARDI, N; FIORELLI, G; IDEO, G; TITTOBELLO, A | 1 |
GAVOSTO, F; MARAINI, G; PILERI, A | 1 |
Griffin, JD; Ikeda, Y; Kizaki, M; Miyakawa, Y; Sawafuji, K; Weisberg, E | 1 |
Fujimaki, K; Ishigatsubo, Y; Kanamori, H; Koharazawa, H; Taguchi, J; Takabayashi, M; Takasaki, H; Yamaji, S | 1 |
Irvine, AE; Lynas, J; Magill, L; Morris, TC; Walker, B | 1 |
Baccarani, M; Bosi, C; Castagnetti, F; Cilloni, D; Colarossi, S; Giannoulia, P; Gnani, A; Iacobucci, I; Luatti, S; Martinelli, G; Marzocchi, G; Palandri, F; Paolini, S; Piccaluga, PP; Rondoni, M; Rosti, G; Saglio, G; Soverini, S; Testoni, N | 1 |
Abe, F; Fujii, H; Sukenaga, Y; Takeuchi, T; Yamada, M | 1 |
Saito, Y; Uzuka, Y | 2 |
Hiraoka, A; Masaoka, T; Shibata, H | 1 |
Catovsky, D; Gill, R; Levi, S; Marshall, CJ; Matutes, E; Urbano-Ispizua, A; Wiedemann, LM | 1 |
Saito, Y; Usuka, Y | 1 |
Im, T; Nakao, H; Oohira, H; Ota, K; Sannomiya, Y; Sasaki, A; Tatsumi, N; Yasui, Y | 1 |
1 trial(s) available for leucine and Granulocytic Leukemia, Chronic
Article | Year |
---|---|
Immunopotentiation with Ubenimex for prevention of leukemia relapse after allogeneic BMT. The Study Group of Ubenimex for BMT.
Topics: Adjuvants, Immunologic; Administration, Oral; Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Chronic Disease; Female; Graft vs Host Disease; Graft vs Host Reaction; Humans; Infant; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Recurrence | 1992 |
15 other study(ies) available for leucine and Granulocytic Leukemia, Chronic
Article | Year |
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Major molecular response achieved with dasatinib in a CML patient with F317L BCR-ABL kinase domain mutation.
Topics: Amino Acid Substitution; Antineoplastic Agents; Cytogenetic Analysis; Dasatinib; Drug Resistance, Neoplasm; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Phenylalanine; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcr; Pyrimidines; Thiazoles; Treatment Outcome | 2010 |
Durable molecular response despite F317L and E255K mutations: Successful treatment of chronic myeloid leukemia with sequential imatinib, nilotinib and dasatinib.
Topics: Adult; Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Pharmacological; Biomarkers, Tumor; Dasatinib; Female; Fusion Proteins, bcr-abl; Glutamic Acid; Humans; Imatinib Mesylate; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lysine; Mutation, Missense; Phenylalanine; Piperazines; Polymorphism, Single Nucleotide; Pyrimidines; Remission Induction; Thiazoles; Time Factors; Treatment Outcome | 2012 |
Bestatin selectively suppresses the growth of leukemic stem/progenitor cells with BCR/ABL mRNA transcript in patients with chronic myelogeneous leukemia.
Topics: Cell Count; Cells, Cultured; Clone Cells; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukotriene C4; Protease Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Stem Cells | 2003 |
CHROMATOGRAPHIC STUDIES ON LEUCINE AMINOPEPTIDASE IN NORMAL HUMAN GRANULOCYTES AND IN CELLS OF ACUTE AND CHRONIC MYELOID LEUKEMIA.
Topics: Aminopeptidases; Blood Chemical Analysis; Chromatography; Granulocytes; Humans; Leucine; Leucyl Aminopeptidase; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukocytes | 1963 |
[Incorporation of tritium-labeled DL-leucine into the blood cells in acute leukosis and in chronic myeloid leukemia].
Topics: Blood Cells; Humans; Leucine; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Tritium | 1960 |
Aminopeptidase inhibitors inhibit proliferation and induce apoptosis of K562 and STI571-resistant K562 cell lines through the MAPK and GSK-3beta pathways.
Topics: Aminopeptidases; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Benzamides; Caspase 3; Caspases; Cell Division; Cyclin D1; Drug Resistance, Neoplasm; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hydroxamic Acids; Imatinib Mesylate; K562 Cells; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mitogen-Activated Protein Kinases; Phosphorylation; Piperazines; Protease Inhibitors; Pyrimidines; Serine; Signal Transduction | 2003 |
Long-term cytogenetic remission with ubenimex monotherapy in a case of chronic myeloid leukemia.
Topics: Aged; Bone Marrow Cells; Busulfan; Humans; Immunologic Factors; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Philadelphia Chromosome; Remission Induction; Time Factors | 2004 |
Proteasome proteolytic activity in hematopoietic cells from patients with chronic myeloid leukemia and multiple myeloma.
Topics: Apoptosis; Bone Marrow Cells; Cell Line, Tumor; Edetic Acid; Fusion Proteins, bcr-abl; Hematopoietic Stem Cells; HL-60 Cells; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Multiple Myeloma; Neoplasm Proteins; Pepstatins; Protease Inhibitors; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Sulfones; Transfection | 2004 |
Presence or the emergence of a F317L BCR-ABL mutation may be associated with resistance to dasatinib in Philadelphia chromosome-positive leukemia.
Topics: Adult; Antineoplastic Agents; Blast Crisis; Clinical Trials, Phase II as Topic; Dasatinib; Disease Progression; Drug Resistance, Neoplasm; Female; Genes, abl; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Mutation; Phenylalanine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrimidines; Thiazoles; Treatment Failure | 2006 |
Purification and characterization of a ubenimex (Bestatin)-sensitive aminopeptidase B-like enzyme from K562 human chronic myeloid leukemia cells.
Topics: Amino Acid Sequence; Aminopeptidases; Cations, Divalent; Chlorides; Humans; Hydrogen-Ion Concentration; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Sequence Data; Molecular Weight; Substrate Specificity; Tumor Cells, Cultured | 1994 |
[Bestatin therapy of chronic myelogenous leukemia].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Female; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Accelerated Phase; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Remission Induction; Survival Rate | 1993 |
Low frequency of ras oncogene mutations in Philadelphia-positive acute leukemia and report of a novel mutation H61 Leu in a single case.
Topics: Codon; Fusion Proteins, bcr-abl; Gene Expression Regulation, Neoplastic; Genes, ras; Glutamine; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Mutation; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transcriptional Activation | 1992 |
Bestatin treatment of myelodysplastic syndromes and chronic myelogenous leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Busulfan; Drug Therapy, Combination; Female; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Myelodysplastic Syndromes | 1991 |
Effects of ubenimex, a biological response modifier, on myelodysplastic syndrome and chronic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Female; Humans; Immunologic Factors; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Myelodysplastic Syndromes | 1991 |
[Combination therapy of chronic myelogenous leukemia with busulfan and bestatin].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Female; Gene Rearrangement; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Remission Induction | 1991 |